TAS2R3 (ta2r3_mouse)

FAMILY

Class T (Taste 2) Sensory receptors Taste 2 receptors TAS2R3

GENE

Tas2r3 (T2r41, Tas2r137, Tas2r37)

ORGANISM

Mouse (Mus musculus)

ALT. NAMES

Taste receptor type 2 member 3, T2R3, T2R137, T2R37, mT2r41

SOURCE

SWISSPROT

SEQUENCE

N-term TM1  
M
F
G
F
I
E
G
V
F
L
10
                   
V
L
T
I
T
E
F
I
L
G
20
                   
N
L
V
N
G
F
I
V
S
I
30
                   
N
S
S
Y
W
F
K
S
K
K
40
ICL1 TM2      
I
S
L
S
N
F
I
I
T
S
50
                   
L
A
L
F
R
I
F
L
L
W
60
                   
I
I
F
I
D
S
L
I
I
V
70
    ECL1   TM3
F
S
Y
Q
T
H
D
S
G
I
80
                   
M
M
Q
L
I
D
V
F
W
T
90
                   
F
T
N
H
F
S
I
W
L
I
100
                   
S
C
L
S
V
F
Y
C
L
K
110
    ICL2        
I
A
S
F
S
H
P
S
F
L
120
        TM4      
W
L
K
W
R
A
S
R
V
V
130
                   
V
G
M
L
W
G
A
L
L
L
140
                   
S
C
V
S
T
M
S
L
M
N
150
      ECL2      
E
F
K
I
Y
S
A
L
T
R
160
                   
S
K
D
T
P
N
M
T
E
Y
170
                   
I
R
L
K
R
Q
E
Y
N
L
180
TM5              
M
H
V
L
G
N
L
W
K
I
190
                   
P
S
L
I
V
S
L
V
A
Y
200
                   
L
L
L
L
L
S
L
G
K
H
210
                   
T
Q
Q
M
Q
Q
Y
S
I
D
220
ICL3 TM6      
S
R
D
Q
S
A
E
A
H
K
230
                   
R
A
M
R
I
I
S
S
F
L
240
                   
L
F
F
L
F
Y
F
L
S
F
250
                   
M
I
L
S
S
S
R
F
L
P
260
ECL3 TM7      
E
T
R
I
A
R
I
I
G
V
270
                   
V
I
S
M
S
Y
L
V
G
D
280
              H8  
S
F
I
L
I
V
C
N
N
K
290
                   
L
K
H
T
F
V
A
M
L
P
300
                   
C
E
C
G
H
L
K
P
G
S
310
C-term
K
G
P
S
A
S

LINKS

UniProt

DIAGRAMS

ICL1 K I ICL1ECL1 Y Q T H D ECL1ICL2 S F S H P S F L W L K W ICL2ECL2 I Y S A L T R S K D T P N M T E Y I R L K R Q E Y N L ECL2ICL3 I D S R ICL3ECL3 P E T ECL3N-term M N-termC-term K P G S K G P S A S C-term F G F I E G V F L V L T I T E F I L G N L V N G F I V S I N S S Y W F K S K S L S N F I I T S L A L F R I F L L W I I F I D S L I I V F S S G I M M Q L I D V F W T F T N H F S I W L I S C L S V F Y C L K I A R A S R V V V G M L W G A L L L S C V S T M S L M N E F K M H V L G N L W K I P S L I V S L V A Y L L L L L S L G K H T Q Q M Q Q Y S D Q S A E A H K R A M R I I S S F L L F F L F Y F L S F M I L S S S R F L R I A R I I G V V I S M S Y L V G D S F I L I V C N N K F V A E C G L K H T M L P C H L
Pick color:
 
 
 
 
 
 
 
 
 
 
 
 




Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

G N V L N G L I F E T I T L V L F V G E 1 T S L A L F R I F L L W I I F I D S L I 2 C S I L W I S F H N T F T W F V D I L Q 3 V V G M L W G A L L L S C V S T M S L M 4 Y A V L S V I L S P I K W L N G L V H M 5 I S S F L L F F L F Y F L S F M I L S S 6 F S D G V L Y S M S I V V G I I R A I 7
Pick color:
 
 
 
 
 
 
 
 
 
 
 
 




Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

ENDOGENOUS LIGANDS

No endogenous ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available