TAS2R10 (tr107_rat)

FAMILY

Class T (Taste 2) Sensory receptors Taste 2 receptors TAS2R10

GENE

Tas2r107 (Tas2r10, Tas2r4)

ORGANISM

Rat (Rattus norvegicus)

ALT. NAMES

Taste receptor type 2 member 107, T2R107, Taste receptor type 2 member 4, T2R4

SOURCE

SWISSPROT

SEQUENCE

N-term TM1  
M
L
S
A
A
E
G
I
L
L
10
                   
C
V
V
T
S
E
A
V
L
G
20
                   
V
L
G
D
T
F
I
A
L
A
30
                   
N
C
M
E
Y
A
K
N
K
K
40
ICL1 TM2      
L
S
K
I
G
F
I
L
I
G
50
                   
L
A
I
S
R
I
G
V
V
W
60
                   
I
I
I
L
Q
G
Y
M
Q
V
70
    ECL1   TM3
F
F
P
H
I
L
T
F
G
N
80
                   
I
T
E
Y
I
T
Y
I
W
V
90
                   
F
L
N
H
L
S
V
W
F
A
100
                   
T
N
L
N
I
L
Y
F
L
K
110
    ICL2        
I
A
N
F
S
N
S
V
F
L
120
        TM4      
W
L
K
S
R
V
R
V
V
F
130
                   
I
F
L
S
G
C
L
L
T
S
140
                   
W
L
L
C
F
P
Q
F
S
K
150
      ECL2      
M
L
N
N
S
K
M
Y
W
G
160
                   
N
T
S
W
L
Q
Q
Q
K
N
170
        TM5      
V
F
L
I
N
Q
S
L
T
N
180
                   
L
G
I
F
F
F
I
I
V
S
190
                   
L
I
T
C
F
L
L
I
V
F
200
                   
L
W
R
H
I
R
Q
M
H
S
210
    ICL3 TM6  
D
G
S
G
L
R
D
L
N
T
220
                   
E
A
H
V
K
A
M
R
V
L
230
                   
I
S
F
A
V
L
F
I
L
H
240
                   
F
V
G
L
S
I
Q
V
L
C
250
      ECL3 TM7
F
F
L
P
Q
N
N
L
L
F
260
                   
I
T
G
L
I
A
T
C
L
Y
270
                   
P
C
G
H
S
I
I
L
I
L
280
  H8              
G
N
K
Q
L
K
Q
A
S
L
290
                   
K
A
L
Q
H
L
T
C
C
E
300
C-term    
T
K
R
N
L
S
V
T

LINKS

UniProt

DIAGRAMS

ICL1 K K L ICL1ECL1 P H I L T ECL1ICL2 N F S N S V F L W L K S ICL2ECL2 N S K M Y W G N T S W L Q Q Q K N V F L I ECL2ICL3 S G L R ICL3ECL3 P Q N ECL3N-term M N-termC-term T K R N L S V T C-term L S A A E G I L L C V V T S E A V L G V L G D T F I A L A N C M E Y A K N S K I G F I L I G L A I S R I G V V W I I I L Q G Y M Q V F F F G N I T E Y I T Y I W V F L N H L S V W F A T N L N I L Y F L K I A R V R V V F I F L S G C L L T S W L L C F P Q F S K M L N N Q S L T N L G I F F F I I V S L I T C F L L I V F L W R H I R Q M H S D G D L N T E A H V K A M R V L I S F A V L F I L H F V G L S I Q V L C F F L N L L F I T G L I A T C L Y P C G H S I I L I L G N K Q S L K L T C L K Q A A L Q H C E
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

T D G L V G L V A E S T V V C L L I G E 1 I G L A I S R I G V V W I I I L Q G Y M 2 N T A F W V S L H N L F V W I Y T I Y E 3 F I F L S G C L L T S W L L C F P Q F S 4 C T I L S V I I F F F I G L N T L S Q N 5 L I S F A V L F I L H F V G L S I Q V L 6 I S H G C P Y L C T A I L G T I F L L 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

ENDOGENOUS LIGANDS

No endogenous ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available