ACKR1 (ackr1_mouse)
FAMILY
Class A (Rhodopsin) Protein receptors Chemokine receptors ACKR1
GENE
Ackr1 (Darc, Dfy, Fy)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
Atypical chemokine receptor 1, Duffy antigen/chemokine receptor, CD234
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
G
|
N
|
C
|
L
|
Y
|
P
|
V
|
E
|
T
|
10 |
L
|
S
|
L
|
D
|
K
|
N
|
G
|
T
|
Q
|
F
|
20 |
T
|
F
|
D
|
S
|
W
|
N
|
Y
|
S
|
F
|
E
|
30 |
D
|
N
|
Y
|
S
|
Y
|
E
|
L
|
S
|
S
|
D
|
40 |
Y
|
S
|
L
|
T
|
P
|
A
|
A
|
P
|
C
|
Y
|
50 |
TM1 | |||||||||
S
|
C
|
N
|
L
|
L
|
D
|
R
|
S
|
S
|
L
|
60 |
P
|
F
|
F
|
M
|
L
|
T
|
S
|
V
|
L
|
G
|
70 |
M
|
L
|
A
|
S
|
G
|
S
|
I
|
L
|
F
|
A
|
80 |
ICL1 | |||||||||
I
|
L
|
R
|
P
|
F
|
F
|
H
|
W
|
Q
|
I
|
90 |
TM2 | |||||||||
C
|
P
|
S
|
W
|
P
|
I
|
L
|
A
|
E
|
L
|
100 |
A
|
V
|
G
|
S
|
A
|
L
|
F
|
S
|
I
|
A
|
110 |
V
|
P
|
I
|
L
|
A
|
P
|
G
|
L
|
H
|
S
|
120 |
ECL1 | TM3 | ||||||||
A
|
H
|
S
|
T
|
A
|
L
|
C
|
N
|
L
|
G
|
130 |
Y
|
W
|
V
|
W
|
Y
|
T
|
S
|
A
|
F
|
A
|
140 |
Q
|
A
|
L
|
L
|
I
|
G
|
C
|
Y
|
A
|
C
|
150 |
L
|
N
|
P
|
R
|
L
|
N
|
I
|
G
|
Q
|
L
|
160 |
TM4 | |||||||||
R
|
G
|
F
|
T
|
L
|
G
|
L
|
S
|
V
|
G
|
170 |
L
|
W
|
G
|
A
|
A
|
A
|
L
|
S
|
G
|
L
|
180 |
ECL2 | |||||||||
P
|
V
|
A
|
L
|
A
|
S
|
D
|
V
|
Y
|
N
|
190 |
G
|
F
|
C
|
T
|
F
|
P
|
S
|
S
|
R
|
D
|
200 |
TM5 | |||||||||
M
|
E
|
A
|
L
|
K
|
Y
|
T
|
H
|
Y
|
A
|
210 |
I
|
C
|
F
|
T
|
I
|
F
|
T
|
V
|
L
|
P
|
220 |
L
|
T
|
L
|
L
|
A
|
A
|
K
|
G
|
L
|
K
|
230 |
ICL3 | TM6 | ||||||||
I
|
A
|
L
|
S
|
K
|
G
|
P
|
G
|
P
|
W
|
240 |
V
|
S
|
V
|
L
|
W
|
I
|
W
|
F
|
I
|
F
|
250 |
W
|
W
|
P
|
H
|
G
|
M
|
V
|
L
|
I
|
F
|
260 |
D
|
A
|
L
|
V
|
R
|
S
|
K
|
T
|
V
|
L
|
270 |
ECL3 | TM7 | ||||||||
L
|
Y
|
T
|
C
|
Q
|
S
|
Q
|
K
|
I
|
L
|
280 |
D
|
A
|
M
|
L
|
N
|
V
|
T
|
E
|
A
|
L
|
290 |
S
|
M
|
L
|
H
|
C
|
V
|
A
|
T
|
P
|
L
|
300 |
H8 | |||||||||
L
|
L
|
A
|
L
|
F
|
C
|
H
|
Q
|
T
|
T
|
310 |
R
|
R
|
S
|
L
|
S
|
S
|
L
|
S
|
L
|
P
|
320 |
C-term | |||||||||
T
|
R
|
Q
|
A
|
S
|
Q
|
M
|
D
|
A
|
L
|
330 |
A
|
G
|
K
|
S
|
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
ENDOGENOUS LIGANDS
No endogenous ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available