LPA5 receptor (lpar5_mouse)
FAMILY
Class A (Rhodopsin) Lipid receptors Lysophospholipid (LPA) receptors LPA5 receptor
GENE
Lpar5 (Gm1072, Gpr92)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
Lysophosphatidic acid receptor 5, LPA receptor 5, LPA-5, G-protein coupled receptor 92
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
F
|
A
|
N
|
S
|
S
|
A
|
N
|
T
|
T
|
10 |
S
|
T
|
N
|
S
|
S
|
V
|
L
|
Q
|
C
|
P
|
20 |
TM1 | |||||||||
D
|
Y
|
R
|
D
|
T
|
H
|
R
|
L
|
H
|
M
|
30 |
V
|
V
|
Y
|
S
|
L
|
V
|
L
|
A
|
T
|
G
|
40 |
L
|
P
|
L
|
N
|
A
|
L
|
A
|
L
|
W
|
V
|
50 |
ICL1 | |||||||||
F
|
L
|
R
|
V
|
L
|
R
|
V
|
H
|
S
|
V
|
60 |
TM2 | |||||||||
V
|
S
|
V
|
Y
|
M
|
C
|
N
|
L
|
A
|
A
|
70 |
S
|
D
|
L
|
L
|
F
|
T
|
L
|
S
|
L
|
P
|
80 |
L
|
R
|
L
|
S
|
Y
|
Y
|
A
|
Q
|
H
|
H
|
90 |
ECL1 | TM3 | ||||||||
W
|
P
|
F
|
P
|
G
|
F
|
L
|
C
|
Q
|
T
|
100 |
S
|
G
|
A
|
I
|
F
|
Q
|
M
|
N
|
M
|
Y
|
110 |
G
|
S
|
C
|
L
|
F
|
L
|
M
|
L
|
I
|
N
|
120 |
V
|
D
|
R
|
Y
|
A
|
A
|
I
|
V
|
H
|
P
|
130 |
ICL2 | TM4 | ||||||||
L
|
R
|
L
|
R
|
H
|
L
|
R
|
R
|
P
|
R
|
140 |
V
|
A
|
R
|
R
|
L
|
C
|
L
|
G
|
V
|
W
|
150 |
A
|
L
|
I
|
L
|
L
|
F
|
A
|
V
|
P
|
A
|
160 |
ECL2 | |||||||||
A
|
R
|
V
|
H
|
S
|
P
|
S
|
H
|
C
|
T
|
170 |
Y
|
K
|
N
|
I
|
T
|
V
|
R
|
L
|
C
|
F
|
180 |
TM5 | |||||||||
E
|
S
|
F
|
S
|
D
|
E
|
L
|
W
|
K
|
G
|
190 |
R
|
L
|
L
|
P
|
L
|
L
|
L
|
L
|
A
|
E
|
200 |
I
|
L
|
G
|
F
|
L
|
L
|
P
|
L
|
A
|
A
|
210 |
V
|
V
|
Y
|
S
|
S
|
G
|
R
|
V
|
F
|
W
|
220 |
ICL3 | |||||||||
T
|
L
|
A
|
R
|
P
|
D
|
A
|
T
|
Q
|
S
|
230 |
TM6 | |||||||||
Q
|
R
|
R
|
R
|
K
|
T
|
V
|
R
|
L
|
L
|
240 |
L
|
A
|
N
|
L
|
I
|
I
|
F
|
L
|
L
|
C
|
250 |
F
|
V
|
P
|
Y
|
N
|
S
|
T
|
L
|
A
|
V
|
260 |
Y
|
G
|
L
|
L
|
R
|
A
|
N
|
L
|
V
|
K
|
270 |
ECL3 | TM7 | ||||||||
N
|
S
|
I
|
Q
|
D
|
R
|
D
|
Q
|
V
|
R
|
280 |
G
|
V
|
L
|
M
|
I
|
M
|
V
|
L
|
L
|
A
|
290 |
G
|
A
|
N
|
C
|
V
|
L
|
D
|
P
|
L
|
V
|
300 |
H8 | |||||||||
Y
|
Y
|
F
|
S
|
A
|
E
|
G
|
F
|
R
|
N
|
310 |
T
|
L
|
R
|
N
|
L
|
G
|
A
|
P
|
L
|
N
|
320 |
C-term | |||||||||
T
|
R
|
P
|
L
|
A
|
T
|
N
|
G
|
A
|
A
|
330 |
G
|
V
|
L
|
T
|
E
|
L
|
P
|
S
|
E
|
S
|
340 |
T
|
Q
|
N
|
T
|
G
|
Q
|
D
|
A
|
T
|
S
|
350 |
Q
|
V
|
L
|
L
|
Q
|
P
|
A
|
T
|
L
|
G
|
360 |
T
|
P
|
P
|
D
|
N
|
C
|
S
|
Q
|
D
|
S
|
370 |
A
|
L
|
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
ENDOGENOUS LIGANDS
No endogenous ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available