oxoglutarate receptor (oxgr1_mouse)
FAMILY
Class A (Rhodopsin) Alicarboxylic acid receptors Oxoglutarate receptors oxoglutarate receptor
GENE
Oxgr1 (Gpr99)
ORGANISM
Mouse (Mus musculus)
ALT. NAMES
2-oxoglutarate receptor 1, Alpha-ketoglutarate receptor 1, G-protein coupled receptor 99
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
I
|
E
|
P
|
L
|
D
|
S
|
P
|
A
|
S
|
10 |
D
|
S
|
D
|
F
|
L
|
D
|
Y
|
P
|
S
|
A
|
20 |
L
|
G
|
N
|
C
|
T
|
D
|
E
|
Q
|
I
|
S
|
30 |
TM1 | |||||||||
F
|
K
|
M
|
Q
|
Y
|
L
|
P
|
V
|
I
|
Y
|
40 |
S
|
I
|
I
|
F
|
L
|
V
|
G
|
F
|
P
|
G
|
50 |
N
|
T
|
V
|
A
|
I
|
S
|
I
|
Y
|
I
|
F
|
60 |
ICL1 | TM2 | ||||||||
K
|
M
|
R
|
P
|
W
|
R
|
G
|
S
|
T
|
V
|
70 |
I
|
M
|
L
|
N
|
L
|
A
|
L
|
T
|
D
|
L
|
80 |
L
|
Y
|
L
|
T
|
S
|
L
|
P
|
F
|
L
|
I
|
90 |
ECL1 | |||||||||
H
|
Y
|
Y
|
A
|
S
|
G
|
E
|
N
|
W
|
I
|
100 |
TM3 | |||||||||
F
|
G
|
D
|
F
|
M
|
C
|
K
|
F
|
I
|
R
|
110 |
F
|
G
|
F
|
H
|
F
|
N
|
L
|
Y
|
S
|
S
|
120 |
I
|
L
|
F
|
L
|
T
|
C
|
F
|
S
|
L
|
F
|
130 |
R
|
Y
|
V
|
V
|
I
|
I
|
H
|
P
|
M
|
S
|
140 |
ICL2 | TM4 | ||||||||
C
|
F
|
S
|
I
|
Q
|
K
|
T
|
R
|
W
|
A
|
150 |
V
|
V
|
A
|
C
|
A
|
G
|
V
|
W
|
V
|
I
|
160 |
S
|
L
|
V
|
A
|
V
|
M
|
P
|
M
|
T
|
F
|
170 |
ECL2 | |||||||||
L
|
I
|
T
|
S
|
T
|
T
|
R
|
T
|
N
|
R
|
180 |
S
|
A
|
C
|
L
|
D
|
L
|
T
|
S
|
S
|
D
|
190 |
TM5 | |||||||||
D
|
L
|
T
|
T
|
I
|
K
|
W
|
Y
|
N
|
L
|
200 |
I
|
L
|
T
|
A
|
T
|
T
|
F
|
C
|
L
|
P
|
210 |
L
|
V
|
I
|
V
|
T
|
L
|
C
|
Y
|
T
|
T
|
220 |
I
|
I
|
S
|
T
|
L
|
T
|
H
|
G
|
P
|
R
|
230 |
ICL3 | TM6 | ||||||||
T
|
H
|
S
|
C
|
F
|
K
|
Q
|
K
|
A
|
R
|
240 |
R
|
L
|
T
|
I
|
L
|
L
|
L
|
L
|
V
|
F
|
250 |
Y
|
I
|
C
|
F
|
L
|
P
|
F
|
H
|
I
|
L
|
260 |
R
|
V
|
I
|
R
|
I
|
E
|
S
|
R
|
L
|
L
|
270 |
ECL3 | TM7 | ||||||||
S
|
I
|
S
|
C
|
S
|
I
|
E
|
S
|
H
|
I
|
280 |
H
|
E
|
A
|
Y
|
I
|
V
|
S
|
R
|
P
|
L
|
290 |
A
|
A
|
L
|
N
|
T
|
F
|
G
|
N
|
L
|
L
|
300 |
H8 | |||||||||
L
|
Y
|
V
|
V
|
V
|
S
|
N
|
N
|
F
|
Q
|
310 |
Q
|
A
|
F
|
C
|
S
|
I
|
V
|
R
|
C
|
K
|
320 |
C-term | |||||||||
A
|
S
|
G
|
D
|
L
|
E
|
Q
|
G
|
K
|
K
|
330 |
D
|
S
|
C
|
S
|
N
|
N
|
P
|
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
No structure models available. Check the Archive on Structure models for earlier releases.
STRUCTURES
No structures available