TAS2R40 (t2r40_mouse)

FAMILY

Class T (Taste 2) Sensory receptors Taste 2 receptors TAS2R40

GENE

Tas2r40 (T2r33, Tas2r144, Tas2r44)

ORGANISM

Mouse (Mus musculus)

ALT. NAMES

Taste receptor type 2 member 40, T2R40, mT2R33

SOURCE

SWISSPROT

SEQUENCE

N-term        
M
A
I
I
T
T
N
S
D
Y
10
    TM1          
F
A
H
R
Y
E
V
I
I
P
20
                   
F
V
V
S
T
I
C
S
I
V
30
                   
G
I
I
G
N
G
F
I
T
V
40
                   
I
Y
G
T
E
W
V
R
S
K
50
ICL1 TM2      
R
L
P
T
G
E
N
L
M
L
60
                   
M
L
S
F
S
R
L
L
L
Q
70
                   
I
W
M
M
V
E
I
T
Y
S
80
      ECL1 TM3
L
L
F
P
I
I
Y
N
H
N
90
                   
A
M
Y
K
L
F
K
A
I
S
100
                   
V
F
L
N
Y
C
N
L
W
F
110
                   
A
A
W
L
N
V
F
Y
C
L
120
      ICL2      
K
I
V
N
L
A
H
P
L
F
130
          TM4    
L
L
M
K
Q
K
I
I
G
L
140
                   
M
P
R
L
L
S
L
S
V
L
150
                   
V
S
F
S
L
S
S
F
F
S
160
        ECL2    
K
D
I
L
N
V
Y
V
N
T
170
                   
S
V
P
I
P
S
S
N
S
T
180
                   
K
M
K
Y
I
F
M
I
N
V
190
    TM5          
L
S
L
A
F
L
Y
Y
M
G
200
                   
I
F
L
P
L
F
M
F
I
M
210
                   
A
A
T
L
L
I
T
S
L
K
220
                   
R
H
T
L
H
M
E
N
S
T
230
ICL3 TM6      
T
G
S
R
D
S
S
M
E
A
240
                   
H
V
G
A
I
K
S
T
S
H
250
                   
S
L
I
L
Y
I
I
N
A
L
260
                   
A
L
F
I
S
M
S
N
I
L
270
  ECL3 TM7    
G
A
Y
S
V
W
N
S
L
C
280
                   
N
I
I
M
T
A
Y
P
A
G
290
                H8
Q
S
V
H
L
I
L
R
N
P
300
                   
G
L
R
R
A
W
R
R
F
Q
310
                 
H
H
V
H
L
Y
L
K
R

LINKS

UniProt

DIAGRAMS

ICL1 R L ICL1ECL1 P I ECL1ICL2 N L A H P L F L L M K Q ICL2ECL2 N V Y V N T S V P I P S S N S T K M K Y I F M I N V L S ECL2ICL3 T G S R ICL3ECL3 A Y ECL3N-term M A I I T T N S D Y F A N-termC-term K R C-term H R Y E V I I P F V V S T I C S I V G I I G N G F I T V I Y G T E W V R S K P T G E N L M L M L S F S R L L L Q I W M M V E I T Y S L L F I Y N H N A M Y K L F K A I S V F L N Y C N L W F A A W L N V F Y C L K I V K I I G L M P R L L S L S V L V S F S L S S F F S K D I L L A F L Y Y M G I F L P L F M F I M A A T L L I T S L K R H T L H M E N S T D S S M E A H V G A I K S T S H S L I L Y I I N A L A L F I S M S N I L G S V W N S L C N I I M T A Y P A G Q S V H L I L R N P G W R R V H L L R R A F Q H H Y L
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

G N G I I G V I S C I T S V V F P I I V 1 L M L S F S R L L L Q I W M M V E I T Y 2 W A A F W L N C Y N L F V S I A K F L K 3 M P R L L S L S V L V S F S L S S F F S 4 A A M I F M F L P L F I G M Y Y L F A L 5 T S H S L I L Y I I N A L A L F I S M S 6 V S Q G A P Y A T M I I N C L S N W V 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

ENDOGENOUS LIGANDS

No endogenous ligands available

STRUCTURE MODELS

No structure models available. Check the Archive on Structure models for earlier releases.

STRUCTURES

No structures available