3RZE_refined

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): 0.45 docs)

VERSION

2019-09-03

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

H1 receptor (sequence similarity: 100%) PDB: 3RZE

TEMPLATES

4AMJ (β1-adrenoceptor)
3RZE (H1 receptor)
3SN6 (β2-adrenoceptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 82.9 8.4 8.7
Side-chains 82.3 6.4 11.4

Number of backbone templates: 3
Number of rotamer templates: 17

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 24 - - - -
N-term 25 - - - -
N-term 26 - - - -
N-term 27 - - - -
N-term 28 - - - -
TM1 29 1.34x34 β1-adrenoceptor 4AMJ - -
TM1 30 1.35x35 β1-adrenoceptor 4AMJ MT1 receptor 6ME2
TM1 31 1.36x36 β1-adrenoceptor 4AMJ M2 receptor 5ZKC
TM1 32 1.37x37 β1-adrenoceptor 4AMJ D4 receptor 5WIV
TM1 33 1.38x38 H1 receptor 3RZE H1 receptor 3RZE
TM1 34 1.39x39 H1 receptor 3RZE H1 receptor 3RZE
TM1 35 1.40x40 H1 receptor 3RZE H1 receptor 3RZE
TM1 36 1.41x41 H1 receptor 3RZE H1 receptor 3RZE
TM1 37 1.42x42 H1 receptor 3RZE H1 receptor 3RZE
TM1 38 1.43x43 H1 receptor 3RZE H1 receptor 3RZE
TM1 39 1.44x44 H1 receptor 3RZE H1 receptor 3RZE
TM1 40 1.45x45 H1 receptor 3RZE H1 receptor 3RZE
TM1 41 1.46x46 H1 receptor 3RZE H1 receptor 3RZE
TM1 42 1.47x47 H1 receptor 3RZE H1 receptor 3RZE
TM1 43 1.48x48 H1 receptor 3RZE H1 receptor 3RZE
TM1 44 1.49x49 H1 receptor 3RZE H1 receptor 3RZE
TM1 45 1.50x50 H1 receptor 3RZE H1 receptor 3RZE
TM1 46 1.51x51 H1 receptor 3RZE H1 receptor 3RZE
TM1 47 1.52x52 H1 receptor 3RZE H1 receptor 3RZE
TM1 48 1.53x53 H1 receptor 3RZE H1 receptor 3RZE
TM1 49 1.54x54 H1 receptor 3RZE H1 receptor 3RZE
TM1 50 1.55x55 H1 receptor 3RZE H1 receptor 3RZE
TM1 51 1.56x56 H1 receptor 3RZE H1 receptor 3RZE
TM1 52 1.57x57 H1 receptor 3RZE H1 receptor 3RZE
TM1 53 1.58x58 H1 receptor 3RZE H1 receptor 3RZE
TM1 54 1.59x59 H1 receptor 3RZE H1 receptor 3RZE
TM1 55 1.60x60 H1 receptor 3RZE H1 receptor 3RZE
ICL1 56 12.48x48 H1 receptor 3RZE H1 receptor 3RZE
ICL1 57 12.49x49 H1 receptor 3RZE H1 receptor 3RZE
ICL1 58 12.50x50 H1 receptor 3RZE H1 receptor 3RZE
ICL1 59 12.51x51 H1 receptor 3RZE H1 receptor 3RZE
TM2 60 2.37x37 H1 receptor 3RZE H1 receptor 3RZE
TM2 61 2.38x38 H1 receptor 3RZE H1 receptor 3RZE
TM2 62 2.39x39 H1 receptor 3RZE H1 receptor 3RZE
TM2 63 2.40x40 H1 receptor 3RZE H1 receptor 3RZE
TM2 64 2.41x41 H1 receptor 3RZE H1 receptor 3RZE
TM2 65 2.42x42 H1 receptor 3RZE H1 receptor 3RZE
TM2 66 2.43x43 H1 receptor 3RZE H1 receptor 3RZE
TM2 67 2.44x44 H1 receptor 3RZE H1 receptor 3RZE
TM2 68 2.45x45 H1 receptor 3RZE H1 receptor 3RZE
TM2 69 2.46x46 H1 receptor 3RZE H1 receptor 3RZE
TM2 70 2.47x47 H1 receptor 3RZE H1 receptor 3RZE
TM2 71 2.48x48 H1 receptor 3RZE H1 receptor 3RZE
TM2 72 2.49x49 H1 receptor 3RZE H1 receptor 3RZE
TM2 73 2.50x50 H1 receptor 3RZE H1 receptor 3RZE
TM2 74 2.51x51 H1 receptor 3RZE H1 receptor 3RZE
TM2 75 2.52x52 H1 receptor 3RZE H1 receptor 3RZE
TM2 76 2.53x53 H1 receptor 3RZE H1 receptor 3RZE
TM2 77 2.54x54 H1 receptor 3RZE H1 receptor 3RZE
TM2 78 2.55x55 H1 receptor 3RZE H1 receptor 3RZE
TM2 79 2.56x551 H1 receptor 3RZE H1 receptor 3RZE
TM2 80 2.57x56 H1 receptor 3RZE H1 receptor 3RZE
TM2 81 2.58x57 H1 receptor 3RZE H1 receptor 3RZE
TM2 82 2.59x58 H1 receptor 3RZE H1 receptor 3RZE
TM2 83 2.60x59 H1 receptor 3RZE H1 receptor 3RZE
TM2 84 2.61x60 H1 receptor 3RZE H1 receptor 3RZE
TM2 85 2.62x61 H1 receptor 3RZE H1 receptor 3RZE
TM2 86 2.63x62 H1 receptor 3RZE H1 receptor 3RZE
TM2 87 2.64x63 H1 receptor 3RZE H1 receptor 3RZE
TM2 88 2.65x64 H1 receptor 3RZE H1 receptor 3RZE
TM2 89 2.66x65 H1 receptor 3RZE H1 receptor 3RZE
TM2 90 2.67x66 H1 receptor 3RZE H1 receptor 3RZE
ECL1 91 H1 receptor 3RZE H1 receptor 3RZE
ECL1 92 23.49x49 H1 receptor 3RZE H1 receptor 3RZE
ECL1 93 23.50x50 H1 receptor 3RZE H1 receptor 3RZE
ECL1 94 23.51x51 H1 receptor 3RZE H1 receptor 3RZE
ECL1 95 23.52x52 H1 receptor 3RZE H1 receptor 3RZE
TM3 96 3.21x21 H1 receptor 3RZE H1 receptor 3RZE
TM3 97 3.22x22 H1 receptor 3RZE H1 receptor 3RZE
TM3 98 3.23x23 H1 receptor 3RZE H1 receptor 3RZE
TM3 99 3.24x24 H1 receptor 3RZE H1 receptor 3RZE
TM3 100 3.25x25 H1 receptor 3RZE H1 receptor 3RZE
TM3 101 3.26x26 H1 receptor 3RZE H1 receptor 3RZE
TM3 102 3.27x27 H1 receptor 3RZE H1 receptor 3RZE
TM3 103 3.28x28 H1 receptor 3RZE H1 receptor 3RZE
TM3 104 3.29x29 H1 receptor 3RZE H1 receptor 3RZE
TM3 105 3.30x30 H1 receptor 3RZE H1 receptor 3RZE
TM3 106 3.31x31 H1 receptor 3RZE H1 receptor 3RZE
TM3 107 3.32x32 H1 receptor 3RZE H1 receptor 3RZE
TM3 108 3.33x33 H1 receptor 3RZE H1 receptor 3RZE
TM3 109 3.34x34 H1 receptor 3RZE H1 receptor 3RZE
TM3 110 3.35x35 H1 receptor 3RZE H1 receptor 3RZE
TM3 111 3.36x36 H1 receptor 3RZE H1 receptor 3RZE
TM3 112 3.37x37 H1 receptor 3RZE H1 receptor 3RZE
TM3 113 3.38x38 H1 receptor 3RZE H1 receptor 3RZE
TM3 114 3.39x39 H1 receptor 3RZE H1 receptor 3RZE
TM3 115 3.40x40 H1 receptor 3RZE H1 receptor 3RZE
TM3 116 3.41x41 H1 receptor 3RZE H1 receptor 3RZE
TM3 117 3.42x42 H1 receptor 3RZE H1 receptor 3RZE
TM3 118 3.43x43 H1 receptor 3RZE H1 receptor 3RZE
TM3 119 3.44x44 H1 receptor 3RZE H1 receptor 3RZE
TM3 120 3.45x45 H1 receptor 3RZE H1 receptor 3RZE
TM3 121 3.46x46 H1 receptor 3RZE H1 receptor 3RZE
TM3 122 3.47x47 H1 receptor 3RZE H1 receptor 3RZE
TM3 123 3.48x48 H1 receptor 3RZE H1 receptor 3RZE
TM3 124 3.49x49 H1 receptor 3RZE H1 receptor 3RZE
TM3 125 3.50x50 H1 receptor 3RZE H1 receptor 3RZE
TM3 126 3.51x51 H1 receptor 3RZE H1 receptor 3RZE
TM3 127 3.52x52 H1 receptor 3RZE H1 receptor 3RZE
TM3 128 3.53x53 H1 receptor 3RZE H1 receptor 3RZE
TM3 129 3.54x54 H1 receptor 3RZE H1 receptor 3RZE
TM3 130 3.55x55 H1 receptor 3RZE H1 receptor 3RZE
TM3 131 3.56x56 H1 receptor 3RZE H1 receptor 3RZE
ICL2 132 34.50x50 - - - -
ICL2 133 34.51x51 β1-adrenoceptor 4AMJ M3 receptor 5ZHP
ICL2 134 34.52x52 β1-adrenoceptor 4AMJ β1-adrenoceptor 4AMJ
ICL2 135 34.53x53 β1-adrenoceptor 4AMJ β1-adrenoceptor 4AMJ
ICL2 136 34.54x54 β1-adrenoceptor 4AMJ μ receptor 4DKL
ICL2 137 34.55x55 β1-adrenoceptor 4AMJ BLT1 receptor 5X33
ICL2 138 34.56x56 β1-adrenoceptor 4AMJ EP4 receptor 5YWY
ICL2 139 34.57x57 - - - -
TM4 140 4.38x38 H1 receptor 3RZE H1 receptor 3RZE
TM4 141 4.39x39 H1 receptor 3RZE H1 receptor 3RZE
TM4 142 4.40x40 H1 receptor 3RZE H1 receptor 3RZE
TM4 143 4.41x41 H1 receptor 3RZE H1 receptor 3RZE
TM4 144 4.42x42 H1 receptor 3RZE H1 receptor 3RZE
TM4 145 4.43x43 H1 receptor 3RZE H1 receptor 3RZE
TM4 146 4.44x44 H1 receptor 3RZE H1 receptor 3RZE
TM4 147 4.45x45 H1 receptor 3RZE H1 receptor 3RZE
TM4 148 4.46x46 H1 receptor 3RZE H1 receptor 3RZE
TM4 149 4.47x47 H1 receptor 3RZE H1 receptor 3RZE
TM4 150 4.48x48 H1 receptor 3RZE H1 receptor 3RZE
TM4 151 4.49x49 H1 receptor 3RZE H1 receptor 3RZE
TM4 152 4.50x50 H1 receptor 3RZE H1 receptor 3RZE
TM4 153 4.51x51 H1 receptor 3RZE H1 receptor 3RZE
TM4 154 4.52x52 H1 receptor 3RZE H1 receptor 3RZE
TM4 155 4.53x53 H1 receptor 3RZE H1 receptor 3RZE
TM4 156 4.54x54 H1 receptor 3RZE H1 receptor 3RZE
TM4 157 4.55x55 H1 receptor 3RZE H1 receptor 3RZE
TM4 158 4.56x57 H1 receptor 3RZE H1 receptor 3RZE
TM4 159 4.57x58 H1 receptor 3RZE H1 receptor 3RZE
TM4 160 4.58x59 H1 receptor 3RZE H1 receptor 3RZE
TM4 161 4.59x60 H1 receptor 3RZE H1 receptor 3RZE
TM4 162 4.60x61 H1 receptor 3RZE H1 receptor 3RZE
TM4 163 4.61x62 H1 receptor 3RZE H1 receptor 3RZE
TM4 164 4.62x63 H1 receptor 3RZE H1 receptor 3RZE
ECL2 165 H1 receptor 3RZE H1 receptor 3RZE
ECL2 166 H1 receptor 3RZE H1 receptor 3RZE
ECL2 167 H1 receptor 3RZE H1 receptor 3RZE
ECL2 168 - - - -
ECL2 169 - - - -
ECL2 170 - - - -
ECL2 171 - - - -
ECL2 172 - - - -
ECL2 173 - - - -
ECL2 174 - - - -
ECL2 175 H1 receptor 3RZE H1 receptor 3RZE
ECL2 176 H1 receptor 3RZE H1 receptor 3RZE
ECL2 177 H1 receptor 3RZE H1 receptor 3RZE
ECL2 178 H1 receptor 3RZE H1 receptor 3RZE
ECL2 179 H1 receptor 3RZE H1 receptor 3RZE
ECL2 180 45.50x50 H1 receptor 3RZE H1 receptor 3RZE
ECL2 181 45.51x51 H1 receptor 3RZE H1 receptor 3RZE
ECL2 182 45.52x52 H1 receptor 3RZE H1 receptor 3RZE
ECL2 183 H1 receptor 3RZE H1 receptor 3RZE
ECL2 184 H1 receptor 3RZE H1 receptor 3RZE
ECL2 185 H1 receptor 3RZE H1 receptor 3RZE
ECL2 186 H1 receptor 3RZE H1 receptor 3RZE
TM5 187 5.35x36 H1 receptor 3RZE H1 receptor 3RZE
TM5 188 5.36x37 H1 receptor 3RZE H1 receptor 3RZE
TM5 189 5.37x38 H1 receptor 3RZE H1 receptor 3RZE
TM5 190 5.38x39 H1 receptor 3RZE H1 receptor 3RZE
TM5 191 5.39x40 H1 receptor 3RZE H1 receptor 3RZE
TM5 192 5.40x41 H1 receptor 3RZE H1 receptor 3RZE
TM5 193 5.41x42 H1 receptor 3RZE H1 receptor 3RZE
TM5 194 5.42x43 H1 receptor 3RZE H1 receptor 3RZE
TM5 195 5.43x44 H1 receptor 3RZE H1 receptor 3RZE
TM5 196 5.44x45 H1 receptor 3RZE H1 receptor 3RZE
TM5 197 5.45x46 H1 receptor 3RZE H1 receptor 3RZE
TM5 198 5.46x461 H1 receptor 3RZE H1 receptor 3RZE
TM5 199 5.47x47 H1 receptor 3RZE H1 receptor 3RZE
TM5 200 5.48x48 H1 receptor 3RZE H1 receptor 3RZE
TM5 201 5.49x49 H1 receptor 3RZE H1 receptor 3RZE
TM5 202 5.50x50 H1 receptor 3RZE H1 receptor 3RZE
TM5 203 5.51x51 H1 receptor 3RZE H1 receptor 3RZE
TM5 204 5.52x52 H1 receptor 3RZE H1 receptor 3RZE
TM5 205 5.53x53 H1 receptor 3RZE H1 receptor 3RZE
TM5 206 5.54x54 H1 receptor 3RZE H1 receptor 3RZE
TM5 207 5.55x55 H1 receptor 3RZE H1 receptor 3RZE
TM5 208 5.56x56 H1 receptor 3RZE H1 receptor 3RZE
TM5 209 5.57x57 H1 receptor 3RZE H1 receptor 3RZE
TM5 210 5.58x58 H1 receptor 3RZE H1 receptor 3RZE
TM5 211 5.59x59 H1 receptor 3RZE H1 receptor 3RZE
TM5 212 5.60x60 H1 receptor 3RZE H1 receptor 3RZE
TM5 213 5.61x61 H1 receptor 3RZE H1 receptor 3RZE
TM5 214 5.62x62 H1 receptor 3RZE H1 receptor 3RZE
TM5 215 5.63x63 H1 receptor 3RZE H1 receptor 3RZE
TM5 216 5.64x64 H1 receptor 3RZE H1 receptor 3RZE
TM5 217 5.65x65 H1 receptor 3RZE H1 receptor 3RZE
TM5 218 5.66x66 β2-adrenoceptor 3SN6 5-HT2C receptor 6BQH
TM5 219 5.67x67 β2-adrenoceptor 3SN6 MT1 receptor 6ME2
TM5 220 5.68x68 β2-adrenoceptor 3SN6 CB1 receptor 5TGZ
TM5 221 5.69x69 β2-adrenoceptor 3SN6 EP3 receptor 6AK3
TM5 222 5.70x70 β2-adrenoceptor 3SN6 β2-adrenoceptor 3SN6
TM5 223 5.71x71 β2-adrenoceptor 3SN6 - -
TM5 224 5.72x72 β2-adrenoceptor 3SN6 - -
TM5 225 5.73x73 β2-adrenoceptor 3SN6 A2A receptor 3VG9
TM5 226 5.74x74 β2-adrenoceptor 3SN6 - -
TM5 227 5.75x75 β2-adrenoceptor 3SN6 - -
TM5 228 5.76x76 β2-adrenoceptor 3SN6 - -
ICL3 229 - - - -
ICL3 230 - - - -
ICL3 231 - - - -
ICL3 232 - - - -
ICL3 233 - - - -
ICL3 399 - - - -
ICL3 400 - - - -
ICL3 401 - - - -
ICL3 402 - - - -
ICL3 403 - - - -
TM6 404 6.24x24 β1-adrenoceptor 4AMJ AT2 receptor 5UNG
TM6 405 6.25x25 β1-adrenoceptor 4AMJ - -
TM6 406 6.26x26 β1-adrenoceptor 4AMJ ETB receptor 5X93
TM6 407 6.27x27 β1-adrenoceptor 4AMJ OX1 receptor 4ZJ8
TM6 408 6.28x28 H1 receptor 3RZE H1 receptor 3RZE
TM6 409 6.29x29 H1 receptor 3RZE H1 receptor 3RZE
TM6 410 6.30x30 H1 receptor 3RZE H1 receptor 3RZE
TM6 411 6.31x31 H1 receptor 3RZE H1 receptor 3RZE
TM6 412 6.32x32 H1 receptor 3RZE H1 receptor 3RZE
TM6 413 6.33x33 H1 receptor 3RZE H1 receptor 3RZE
TM6 414 6.34x34 H1 receptor 3RZE H1 receptor 3RZE
TM6 415 6.35x35 H1 receptor 3RZE H1 receptor 3RZE
TM6 416 6.36x36 H1 receptor 3RZE H1 receptor 3RZE
TM6 417 6.37x37 H1 receptor 3RZE H1 receptor 3RZE
TM6 418 6.38x38 H1 receptor 3RZE H1 receptor 3RZE
TM6 419 6.39x39 H1 receptor 3RZE H1 receptor 3RZE
TM6 420 6.40x40 H1 receptor 3RZE H1 receptor 3RZE
TM6 421 6.41x41 H1 receptor 3RZE H1 receptor 3RZE
TM6 422 6.42x42 H1 receptor 3RZE H1 receptor 3RZE
TM6 423 6.43x43 H1 receptor 3RZE H1 receptor 3RZE
TM6 424 6.44x44 H1 receptor 3RZE H1 receptor 3RZE
TM6 425 6.45x45 H1 receptor 3RZE H1 receptor 3RZE
TM6 426 6.46x46 H1 receptor 3RZE H1 receptor 3RZE
TM6 427 6.47x47 H1 receptor 3RZE H1 receptor 3RZE
TM6 428 6.48x48 H1 receptor 3RZE H1 receptor 3RZE
TM6 429 6.49x49 H1 receptor 3RZE H1 receptor 3RZE
TM6 430 6.50x50 H1 receptor 3RZE H1 receptor 3RZE
TM6 431 6.51x51 H1 receptor 3RZE H1 receptor 3RZE
TM6 432 6.52x52 H1 receptor 3RZE H1 receptor 3RZE
TM6 433 6.53x53 H1 receptor 3RZE H1 receptor 3RZE
TM6 434 6.54x54 H1 receptor 3RZE H1 receptor 3RZE
TM6 435 6.55x55 H1 receptor 3RZE H1 receptor 3RZE
TM6 436 6.56x56 H1 receptor 3RZE H1 receptor 3RZE
TM6 437 6.57x57 H1 receptor 3RZE H1 receptor 3RZE
TM6 438 6.58x58 H1 receptor 3RZE H1 receptor 3RZE
TM6 439 6.59x59 H1 receptor 3RZE H1 receptor 3RZE
TM6 440 6.60x60 H1 receptor 3RZE H1 receptor 3RZE
TM6 441 6.61x61 H1 receptor 3RZE H1 receptor 3RZE
ECL3 442 H1 receptor 3RZE - -
ECL3 443 H1 receptor 3RZE H1 receptor 3RZE
ECL3 444 H1 receptor 3RZE H1 receptor 3RZE
ECL3 445 H1 receptor 3RZE H1 receptor 3RZE
TM7 446 7.31x30 H1 receptor 3RZE H1 receptor 3RZE
TM7 447 7.32x31 H1 receptor 3RZE H1 receptor 3RZE
TM7 448 7.33x32 H1 receptor 3RZE H1 receptor 3RZE
TM7 449 7.34x33 H1 receptor 3RZE H1 receptor 3RZE
TM7 450 7.35x34 H1 receptor 3RZE H1 receptor 3RZE
TM7 451 7.36x35 H1 receptor 3RZE H1 receptor 3RZE
TM7 452 7.37x36 H1 receptor 3RZE H1 receptor 3RZE
TM7 453 7.38x37 H1 receptor 3RZE H1 receptor 3RZE
TM7 454 7.39x38 H1 receptor 3RZE H1 receptor 3RZE
TM7 455 7.40x39 H1 receptor 3RZE H1 receptor 3RZE
TM7 456 7.41x40 H1 receptor 3RZE H1 receptor 3RZE
TM7 457 7.42x41 H1 receptor 3RZE H1 receptor 3RZE
TM7 458 7.43x42 H1 receptor 3RZE H1 receptor 3RZE
TM7 459 7.44x43 H1 receptor 3RZE H1 receptor 3RZE
TM7 460 7.45x45 H1 receptor 3RZE H1 receptor 3RZE
TM7 461 7.46x46 H1 receptor 3RZE H1 receptor 3RZE
TM7 462 7.47x47 H1 receptor 3RZE H1 receptor 3RZE
TM7 463 7.48x48 H1 receptor 3RZE H1 receptor 3RZE
TM7 464 7.49x49 H1 receptor 3RZE H1 receptor 3RZE
TM7 465 7.50x50 H1 receptor 3RZE H1 receptor 3RZE
TM7 466 7.51x51 H1 receptor 3RZE H1 receptor 3RZE
TM7 467 7.52x52 H1 receptor 3RZE H1 receptor 3RZE
TM7 468 7.53x53 H1 receptor 3RZE H1 receptor 3RZE
TM7 469 7.54x54 H1 receptor 3RZE H1 receptor 3RZE
TM7 470 7.55x55 H1 receptor 3RZE H1 receptor 3RZE
TM7 471 7.56x56 H1 receptor 3RZE H1 receptor 3RZE
H8 472 8.47x47 H1 receptor 3RZE H1 receptor 3RZE
H8 473 8.48x48 H1 receptor 3RZE H1 receptor 3RZE
H8 474 8.49x49 H1 receptor 3RZE H1 receptor 3RZE
H8 475 8.50x50 H1 receptor 3RZE H1 receptor 3RZE
H8 476 8.51x51 H1 receptor 3RZE H1 receptor 3RZE
H8 477 8.52x52 H1 receptor 3RZE H1 receptor 3RZE
H8 478 8.53x53 H1 receptor 3RZE H1 receptor 3RZE
H8 479 8.54x54 H1 receptor 3RZE H1 receptor 3RZE
H8 480 8.55x55 H1 receptor 3RZE H1 receptor 3RZE
H8 481 8.56x56 H1 receptor 3RZE β1-adrenoceptor 4AMJ
H8 482 8.57x57 H1 receptor 3RZE H1 receptor 3RZE
H8 483 8.58x58 H1 receptor 3RZE H1 receptor 3RZE
H8 484 8.59x59 H1 receptor 3RZE H1 receptor 3RZE
C-term 485 H1 receptor 3RZE H1 receptor 3RZE
C-term 486 - - - -
C-term 487 - - - -