5T1A_refined

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

CCR2

SPECIES

Homo sapiens

STATE

Inactive

VERSION

2020-09-02

MODEL

Download

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

CCR2 (sequence similarity: 100%) PDB: 5T1A

TEMPLATES

5T1A (CCR2)
6GPX (CCR2)
6GPS (CCR2)
6WWZ (CCR6)
6MEO (CCR5)
5UIW (CCR5)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 88.1 6.5 5.4
Side-chains 82.3 9.9 7.8

Number of backbone templates: 6
Number of rotamer templates: 11

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 32 C - - - -
N-term 33 H - - - -
N-term 34 K - - - -
N-term 35 F - - - -
N-term 36 D - - - -
TM1 37 V 1.27x27 CCR2 5T1A CCR2 5T1A
TM1 38 K 1.28x28 CCR2 5T1A CCR5 5UIW
TM1 39 Q 1.29x29 CCR2 5T1A CCR5 5UIW
TM1 40 I 1.30x30 CCR2 5T1A CCR2 5T1A
TM1 41 G 1.31x31 CCR2 5T1A CCR2 5T1A
TM1 42 A 1.32x32 CCR2 5T1A CCR2 5T1A
TM1 43 Q 1.33x33 CCR2 5T1A CCR2 5T1A
TM1 44 L 1.34x34 CCR2 5T1A CCR2 5T1A
TM1 45 L 1.35x35 CCR2 5T1A CCR2 5T1A
TM1 46 P 1.36x36 CCR2 5T1A CCR2 5T1A
TM1 47 P 1.37x37 CCR2 5T1A CCR2 5T1A
TM1 48 L 1.38x38 CCR2 5T1A CCR2 5T1A
TM1 49 Y 1.39x39 CCR2 5T1A CCR2 5T1A
TM1 50 S 1.40x40 CCR2 5T1A CCR2 5T1A
TM1 51 L 1.41x41 CCR2 5T1A CCR2 5T1A
TM1 52 V 1.42x42 CCR2 5T1A CCR2 5T1A
TM1 53 F 1.43x43 CCR2 5T1A CCR2 5T1A
TM1 54 I 1.44x44 CCR2 5T1A CCR2 5T1A
TM1 55 F 1.45x45 CCR2 5T1A CCR2 5T1A
TM1 56 G 1.46x46 CCR2 5T1A CCR2 5T1A
TM1 57 F 1.47x47 CCR2 5T1A CCR2 5T1A
TM1 58 V 1.48x48 CCR2 5T1A CCR2 5T1A
TM1 59 G 1.49x49 CCR2 5T1A CCR2 5T1A
TM1 60 N 1.50x50 CCR2 5T1A CCR2 5T1A
TM1 61 M 1.51x51 CCR2 5T1A CCR2 5T1A
TM1 62 L 1.52x52 CCR2 5T1A CCR2 5T1A
TM1 63 V 1.53x53 CCR2 5T1A CCR2 5T1A
TM1 64 V 1.54x54 CCR2 5T1A CCR2 5T1A
TM1 65 L 1.55x55 CCR2 5T1A CCR2 5T1A
TM1 66 I 1.56x56 CCR2 5T1A CCR2 5T1A
TM1 67 L 1.57x57 CCR2 5T1A CCR2 5T1A
TM1 68 I 1.58x58 CCR2 5T1A CCR2 5T1A
TM1 69 N 1.59x59 CCR2 5T1A CCR2 5T1A
TM1 70 C 1.60x60 CCR2 5T1A CCR2 5T1A
ICL1 71 K 12.48x48 - - - -
ICL1 72 K 12.49x49 CCR6 6WWZ - -
ICL1 73 L 12.50x50 CCR6 6WWZ CCR7 6QZH
ICL1 74 K 12.51x51 - - - -
TM2 75 C 2.37x37 CCR2 5T1A CCR2 5T1A
TM2 76 L 2.38x38 CCR2 5T1A CCR2 5T1A
TM2 77 T 2.39x39 CCR2 5T1A CCR2 5T1A
TM2 78 D 2.40x40 CCR2 5T1A CCR2 5T1A
TM2 79 I 2.41x41 CCR2 5T1A CCR2 5T1A
TM2 80 Y 2.42x42 CCR2 5T1A CCR2 5T1A
TM2 81 L 2.43x43 CCR2 5T1A CCR2 5T1A
TM2 82 L 2.44x44 CCR2 5T1A CCR2 5T1A
TM2 83 N 2.45x45 CCR2 5T1A CCR2 5T1A
TM2 84 L 2.46x46 CCR2 5T1A CCR2 5T1A
TM2 85 A 2.47x47 CCR2 5T1A CCR2 5T1A
TM2 86 I 2.48x48 CCR2 5T1A CCR2 5T1A
TM2 87 S 2.49x49 CCR2 5T1A CCR2 5T1A
TM2 88 D 2.50x50 CCR2 5T1A CCR2 5T1A
TM2 89 L 2.51x51 CCR2 5T1A CCR2 5T1A
TM2 90 L 2.52x52 CCR2 5T1A CCR2 5T1A
TM2 91 F 2.53x53 CCR2 5T1A CCR2 5T1A
TM2 92 L 2.54x54 CCR2 5T1A CCR2 5T1A
TM2 93 I 2.55x55 CCR2 5T1A CCR2 5T1A
TM2 94 T 2.56x56 CCR2 5T1A CCR2 5T1A
TM2 95 L 2.57x57 CCR2 5T1A CCR2 5T1A
TM2 96 P 2.58x58 CCR2 5T1A CCR2 5T1A
TM2 97 L 2.59x59 CCR2 5T1A CCR2 5T1A
TM2 98 W 2.60x60 CCR2 5T1A CCR2 5T1A
TM2 99 A 2.61x61 CCR2 5T1A CCR2 5T1A
TM2 100 H 2.62x62 CCR2 5T1A CCR2 5T1A
TM2 101 S 2.63x63 CCR2 5T1A CCR2 5T1A
TM2 102 A 2.64x64 CCR2 5T1A CCR2 5T1A
TM2 103 A 2.65x65 CCR2 5T1A CCR2 5T1A
TM2 104 N 2.66x66 CCR2 5T1A CCR2 5T1A
ECL1 105 E 23.49x49 CCR2 5T1A CCR2 5T1A
ECL1 106 W 23.50x50 CCR2 5T1A CCR2 5T1A
ECL1 107 V 23.51x51 CCR2 5T1A CCR2 5T1A
ECL1 108 F 23.52x52 CCR2 5T1A CCR2 5T1A
TM3 109 G 3.21x21 CCR2 5T1A CCR2 5T1A
TM3 110 N 3.22x22 CCR2 5T1A CCR2 5T1A
TM3 111 A 3.23x23 CCR2 5T1A CCR2 5T1A
TM3 112 M 3.24x24 CCR2 5T1A CCR2 5T1A
TM3 113 C 3.25x25 CCR2 5T1A CCR2 5T1A
TM3 114 K 3.26x26 CCR2 5T1A CCR2 5T1A
TM3 115 L 3.27x27 CCR2 5T1A CCR2 5T1A
TM3 116 F 3.28x28 CCR2 5T1A CCR2 5T1A
TM3 117 T 3.29x29 CCR2 5T1A CCR2 5T1A
TM3 118 G 3.30x30 CCR2 5T1A CCR2 5T1A
TM3 119 L 3.31x31 CCR2 5T1A CCR2 5T1A
TM3 120 Y 3.32x32 CCR2 5T1A CCR2 5T1A
TM3 121 H 3.33x33 CCR2 5T1A CCR2 5T1A
TM3 122 I 3.34x34 CCR2 5T1A CCR2 5T1A
TM3 123 G 3.35x35 CCR2 5T1A CCR2 5T1A
TM3 124 Y 3.36x36 CCR2 5T1A CCR2 5T1A
TM3 125 F 3.37x37 CCR2 5T1A CCR2 5T1A
TM3 126 G 3.38x38 CCR2 5T1A CCR2 5T1A
TM3 127 G 3.39x39 CCR2 5T1A CCR2 5T1A
TM3 128 I 3.40x40 CCR2 5T1A CCR2 5T1A
TM3 129 F 3.41x41 CCR2 5T1A CCR2 5T1A
TM3 130 F 3.42x42 CCR2 5T1A CCR2 5T1A
TM3 131 I 3.43x43 CCR2 5T1A CCR2 5T1A
TM3 132 I 3.44x44 CCR2 5T1A CCR2 5T1A
TM3 133 L 3.45x45 CCR2 5T1A CCR2 5T1A
TM3 134 L 3.46x46 CCR2 5T1A CCR2 5T1A
TM3 135 T 3.47x47 CCR2 5T1A CCR2 5T1A
TM3 136 I 3.48x48 CCR2 5T1A CCR2 5T1A
TM3 137 D 3.49x49 CCR2 5T1A CCR2 5T1A
TM3 138 R 3.50x50 CCR2 5T1A CCR2 5T1A
TM3 139 Y 3.51x51 CCR2 5T1A CCR2 5T1A
TM3 140 L 3.52x52 CCR2 5T1A CCR2 5T1A
TM3 141 A 3.53x53 CCR2 5T1A CCR2 5T1A
TM3 142 I 3.54x54 CCR2 5T1A CCR2 5T1A
TM3 143 V 3.55x55 CCR2 5T1A CCR2 5T1A
TM3 144 H 3.56x56 CCR2 5T1A CCR2 5T1A
ICL2 145 A 34.50x50 CCR2 5T1A CCR2 5T1A
ICL2 146 V 34.51x51 CCR2 5T1A CCR2 5T1A
ICL2 147 F 34.52x52 CCR2 5T1A CCR2 5T1A
ICL2 148 A 34.53x53 CCR2 5T1A CCR2 5T1A
ICL2 149 L 34.54x54 CCR2 5T1A CCR2 5T1A
ICL2 150 K 34.55x55 CCR2 5T1A CCR5 6MEO
ICL2 151 A 34.56x56 CCR2 5T1A CCR2 5T1A
ICL2 152 R 34.57x57 CCR2 5T1A CCR2 5T1A
TM4 153 T 4.38x38 CCR2 5T1A CCR2 5T1A
TM4 154 V 4.39x39 CCR2 5T1A CCR2 5T1A
TM4 155 T 4.40x40 CCR2 5T1A CCR2 5T1A
TM4 156 F 4.41x41 CCR2 5T1A CCR2 5T1A
TM4 157 G 4.42x42 CCR2 5T1A CCR2 5T1A
TM4 158 V 4.43x43 CCR2 5T1A CCR2 5T1A
TM4 159 V 4.44x44 CCR2 5T1A CCR2 5T1A
TM4 160 T 4.45x45 CCR2 5T1A CCR2 5T1A
TM4 161 S 4.46x46 CCR2 5T1A CCR2 5T1A
TM4 162 V 4.47x47 CCR2 5T1A CCR2 5T1A
TM4 163 I 4.48x48 CCR2 5T1A CCR2 5T1A
TM4 164 T 4.49x49 CCR2 5T1A CCR2 5T1A
TM4 165 W 4.50x50 CCR2 5T1A CCR2 5T1A
TM4 166 L 4.51x51 CCR2 5T1A CCR2 5T1A
TM4 167 V 4.52x52 CCR2 5T1A CCR2 5T1A
TM4 168 A 4.53x53 CCR2 5T1A CCR2 5T1A
TM4 169 V 4.54x54 CCR2 5T1A CCR2 5T1A
TM4 170 F 4.55x55 CCR2 5T1A CCR2 5T1A
TM4 171 A 4.56x56 CCR2 5T1A CCR2 5T1A
TM4 172 S 4.57x57 CCR2 5T1A CCR2 5T1A
TM4 173 V 4.58x59 CCR2 5T1A CCR2 5T1A
TM4 174 P 4.59x60 CCR2 5T1A CCR2 5T1A
TM4 175 G 4.60x61 CCR2 5T1A CCR2 5T1A
TM4 176 I 4.61x62 CCR2 5T1A CCR2 5T1A
TM4 177 I 4.62x63 CCR2 5T1A CCR2 5T1A
TM4 178 F 4.63x64 CCR2 5T1A CCR2 5T1A
TM4 179 T 4.64x65 CCR2 5T1A CCR2 5T1A
ECL2 180 K CCR2 5T1A CCR2 5T1A
ECL2 181 C CCR2 5T1A CCR2 5T1A
ECL2 182 Q CCR2 5T1A CCR2 5T1A
ECL2 183 K CCR2 5T1A - -
ECL2 184 E CCR2 5T1A CCR2 5T1A
ECL2 185 D CCR2 5T1A - -
ECL2 186 S CCR2 5T1A - -
ECL2 187 V CCR2 5T1A CCR2 5T1A
ECL2 188 Y CCR2 5T1A CCR2 5T1A
ECL2 189 V CCR2 5T1A CCR2 5T1A
ECL2 190 C 45.50x50 CCR2 5T1A CCR2 5T1A
ECL2 191 G 45.51x51 CCR2 5T1A CCR2 5T1A
ECL2 192 P 45.52x52 CCR2 5T1A CCR2 5T1A
ECL2 193 Y CCR2 5T1A CCR2 5T1A
ECL2 194 F CCR2 5T1A CCR2 5T1A
TM5 195 P 5.31x32 CCR2 5T1A CCR2 5T1A
TM5 196 R 5.32x33 CCR2 5T1A - -
TM5 197 G 5.33x34 CCR2 5T1A CCR2 5T1A
TM5 198 W 5.34x35 CCR2 5T1A CCR2 5T1A
TM5 199 N 5.35x36 CCR2 5T1A CCR2 5T1A
TM5 200 N 5.36x37 CCR2 5T1A CCR2 5T1A
TM5 201 F 5.37x38 CCR2 5T1A CCR2 5T1A
TM5 202 H 5.38x39 CCR2 5T1A CCR2 5T1A
TM5 203 T 5.39x40 CCR2 5T1A CCR2 5T1A
TM5 204 I 5.40x41 CCR2 5T1A CCR2 5T1A
TM5 205 M 5.41x42 CCR2 5T1A CCR2 5T1A
TM5 206 R 5.42x43 CCR2 5T1A CCR2 5T1A
TM5 207 N 5.43x44 CCR2 5T1A CCR2 5T1A
TM5 208 I 5.44x45 CCR2 5T1A CCR2 5T1A
TM5 209 L 5.45x46 CCR2 5T1A CCR2 5T1A
TM5 210 G 5.46x461 CCR2 5T1A CCR2 5T1A
TM5 211 L 5.47x47 CCR2 5T1A CCR2 5T1A
TM5 212 V 5.48x48 CCR2 5T1A CCR2 5T1A
TM5 213 L 5.49x49 CCR2 5T1A CCR2 5T1A
TM5 214 P 5.50x50 CCR2 5T1A CCR2 5T1A
TM5 215 L 5.51x51 CCR2 5T1A CCR2 5T1A
TM5 216 L 5.52x52 CCR2 5T1A CCR2 5T1A
TM5 217 I 5.53x53 CCR2 5T1A CCR2 5T1A
TM5 218 M 5.54x54 CCR2 5T1A CCR2 5T1A
TM5 219 V 5.55x55 CCR2 5T1A CCR2 5T1A
TM5 220 I 5.56x56 CCR2 5T1A CCR2 5T1A
TM5 221 C 5.57x57 CCR2 5T1A CCR2 5T1A
TM5 222 Y 5.58x58 CCR2 5T1A CCR2 5T1A
TM5 223 S 5.59x59 CCR2 5T1A CCR5 5UIW
TM5 224 G 5.60x60 CCR2 5T1A CCR2 5T1A
TM5 225 I 5.61x61 CCR2 5T1A CCR2 5T1A
TM5 226 L 5.62x62 CCR5 6MEO CCR5 6MEO
TM5 227 K 5.63x63 CCR5 6MEO CCR5 6MEO
TM5 228 T 5.64x64 CCR5 6MEO CCR5 6MEO
TM5 229 L 5.65x65 CCR5 6MEO CCR5 6MEO
TM5 230 L 5.66x66 CCR5 6MEO CCR5 6MEO
TM5 231 R 5.67x67 CCR5 6MEO CCR5 6MEO
TM5 232 C 5.68x68 CCR5 6MEO CCR5 6MEO
ICL3 233 R - - - -
ICL3 234 N CCR5 6MEO CCR5 6MEO
ICL3 235 E - - - -
TM6 236 K 6.28x28 CCR5 5UIW CCR5 5UIW
TM6 237 K 6.29x29 CCR5 5UIW CCR5 6AKX
TM6 238 R 6.30x30 CCR5 5UIW CCR5 5UIW
TM6 239 H 6.31x31 CCR5 5UIW CCR5 4MBS
TM6 240 R 6.32x32 CCR5 5UIW CCR5 5UIW
TM6 241 A 6.33x33 CCR2 5T1A CCR2 5T1A
TM6 242 V 6.34x34 CCR2 5T1A CCR2 5T1A
TM6 243 R 6.35x35 CCR2 5T1A CCR2 5T1A
TM6 244 V 6.36x36 CCR2 5T1A CCR2 5T1A
TM6 245 I 6.37x37 CCR2 5T1A CCR2 5T1A
TM6 246 F 6.38x38 CCR2 5T1A CCR2 5T1A
TM6 247 T 6.39x39 CCR2 5T1A CCR2 5T1A
TM6 248 I 6.40x40 CCR2 5T1A CCR2 5T1A
TM6 249 M 6.41x41 CCR2 5T1A CCR2 5T1A
TM6 250 I 6.42x42 CCR2 5T1A CCR2 5T1A
TM6 251 V 6.43x43 CCR2 5T1A CCR2 5T1A
TM6 252 Y 6.44x44 CCR2 5T1A CCR2 5T1A
TM6 253 F 6.45x45 CCR2 5T1A CCR2 5T1A
TM6 254 L 6.46x46 CCR2 5T1A CCR2 5T1A
TM6 255 F 6.47x47 CCR2 5T1A CCR2 5T1A
TM6 256 W 6.48x48 CCR2 5T1A CCR2 5T1A
TM6 257 T 6.49x49 CCR2 5T1A CCR2 5T1A
TM6 258 P 6.50x50 CCR2 5T1A CCR2 5T1A
TM6 259 Y 6.51x51 CCR2 5T1A CCR2 5T1A
TM6 260 N 6.52x52 CCR2 5T1A CCR2 5T1A
TM6 261 I 6.53x53 CCR2 5T1A CCR2 5T1A
TM6 262 V 6.54x54 CCR2 5T1A CCR2 5T1A
TM6 263 I 6.55x55 CCR2 5T1A CCR2 5T1A
TM6 264 L 6.56x56 CCR2 5T1A CCR2 5T1A
TM6 265 L 6.57x57 CCR2 5T1A CCR2 5T1A
TM6 266 N 6.58x58 CCR2 5T1A CCR2 5T1A
TM6 267 T 6.59x59 CCR2 5T1A CCR2 5T1A
TM6 268 F 6.60x60 CCR2 5T1A CCR5 5UIW
TM6 269 Q 6.61x61 CCR2 5T1A CCR2 5T1A
TM6 270 E 6.62x62 CCR2 5T1A CCR2 5T1A
TM6 271 F 6.63x63 CCR2 5T1A CCR5 6AKX
TM6 272 F 6.64x64 CCR2 5T1A CCR2 5T1A
TM6 273 G 6.65x65 CCR2 5T1A CCR2 5T1A
ECL3 274 L - - - -
ECL3 275 S - - - -
TM7 276 N 7.24x23 CCR2 6GPX CCR2 6GPX
TM7 277 C 7.25x24 CCR2 6GPX CCR2 6GPX
TM7 278 E 7.26x25 CCR2 5T1A CCR7 6QZH
TM7 279 S 7.27x26 CCR2 5T1A CCR2 5T1A
TM7 280 T 7.28x27 CCR2 5T1A CCR2 5T1A
TM7 281 S 7.29x28 CCR2 5T1A CCR2 5T1A
TM7 282 Q 7.30x29 CCR2 5T1A CCR2 5T1A
TM7 283 L 7.31x30 CCR2 5T1A CCR2 5T1A
TM7 284 D 7.32x31 CCR2 5T1A CCR2 5T1A
TM7 285 Q 7.33x32 CCR2 5T1A CCR5 5UIW
TM7 286 A 7.34x33 CCR2 5T1A CCR2 5T1A
TM7 287 T 7.35x34 CCR2 5T1A CCR2 5T1A
TM7 288 Q 7.36x35 CCR2 5T1A CCR2 5T1A
TM7 289 V 7.37x36 CCR2 5T1A CCR2 5T1A
TM7 290 T 7.38x37 CCR2 5T1A CCR2 5T1A
TM7 291 E 7.39x38 CCR2 5T1A CCR2 5T1A
TM7 292 T 7.40x39 CCR2 5T1A CCR2 5T1A
TM7 293 L 7.41x40 CCR2 5T1A CCR2 5T1A
TM7 294 G 7.42x41 CCR2 5T1A CCR2 5T1A
TM7 295 M 7.43x42 CCR2 5T1A CCR2 5T1A
TM7 296 T 7.44x43 CCR2 5T1A CCR2 5T1A
TM7 297 H 7.45x45 CCR2 5T1A CCR2 5T1A
TM7 298 C 7.46x46 CCR2 5T1A CCR2 5T1A
TM7 299 C 7.47x47 CCR2 5T1A CCR2 5T1A
TM7 300 I 7.48x48 CCR2 5T1A CCR2 5T1A
TM7 301 N 7.49x49 CCR2 5T1A CCR2 5T1A
TM7 302 P 7.50x50 CCR2 5T1A CCR2 5T1A
TM7 303 I 7.51x51 CCR2 5T1A CCR2 5T1A
TM7 304 I 7.52x52 CCR2 5T1A CCR2 5T1A
TM7 305 Y 7.53x53 CCR2 5T1A CCR2 5T1A
TM7 306 A 7.54x54 CCR2 5T1A CCR2 5T1A
TM7 307 F 7.55x55 CCR2 5T1A CCR2 5T1A
TM7 308 V 7.56x56 CCR2 5T1A CCR2 5T1A
H8 309 G 8.47x47 CCR2 5T1A CCR2 5T1A
H8 310 E 8.48x48 CCR2 5T1A CCR2 5T1A
H8 311 K 8.49x49 CCR2 5T1A CCR2 5T1A
H8 312 F 8.50x50 CCR2 5T1A CCR2 5T1A
H8 313 R 8.51x51 CCR2 5T1A CCR2 5T1A
H8 314 S 8.52x52 CCR2 5T1A 5-HT2A receptor 6A94
H8 315 L 8.53x53 CCR2 5T1A - -
H8 316 F 8.54x54 CCR2 5T1A κ receptor 6VI4
H8 317 H 8.55x55 CCR2 5T1A CB2 receptor 5ZTY
H8 318 I 8.56x56 CCR2 5T1A - -
H8 319 A 8.57x57 CCR2 6GPS CCR2 6GPS
H8 320 L 8.58x58 CCR2 6GPS CCR2 6GPS
C-term 321 G - - - -
C-term 322 C - - - -
C-term 323 R - - - -
C-term 324 I - - - -
C-term 325 A - - - -