5UIW_refined

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): 10.11 docs)

VERSION

2019-09-03

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

NGL is a WebGL based 3D viewer powered by MMTF.

MAIN TEMPLATE

CCR5 (sequence similarity: 60%) PDB: 5UIW

TEMPLATES

5UIW (CCR5)
6MEO (CCR5)
4ZUD (AT1 receptor)
5LWE (CCR9)
6J21 (NK1 receptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 84.8 9.7 5.5
Side-chains 34.3 53.7 12.0

Number of backbone templates: 5
Number of rotamer templates: 24

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 38 CCR5 5UIW CCR5 5UIW
N-term 39 CCR5 5UIW CCR5 5UIW
N-term 40 CCR5 5UIW CCR5 5UIW
N-term 41 CCR5 5UIW CCR5 5UIW
N-term 42 CCR5 5UIW CCR5 5UIW
TM1 43 1.27x27 CCR5 5UIW CCR5 5UIW
TM1 44 1.28x28 CCR5 5UIW CCR9 5LWE
TM1 45 1.29x29 CCR5 5UIW CCR5 5UIW
TM1 46 1.30x30 CCR5 5UIW CCR9 5LWE
TM1 47 1.31x31 CCR5 5UIW CCR5 5UIW
TM1 48 1.32x32 CCR5 5UIW CCR9 5LWE
TM1 49 1.33x33 CCR5 5UIW CCR9 5LWE
TM1 50 1.34x34 CCR5 5UIW CCR9 5LWE
TM1 51 1.35x35 CCR5 5UIW CCR5 5UIW
TM1 52 1.36x36 CCR5 5UIW CCR5 5UIW
TM1 53 1.37x37 CCR5 5UIW CCR5 5UIW
TM1 54 1.38x38 CCR5 5UIW CCR5 5UIW
TM1 55 1.39x39 CCR5 5UIW CCR5 5UIW
TM1 56 1.40x40 CCR5 5UIW CCR9 5LWE
TM1 57 1.41x41 CCR5 5UIW CCR5 5UIW
TM1 58 1.42x42 CCR5 5UIW CCR5 5UIW
TM1 59 1.43x43 CCR5 5UIW CCR5 5UIW
TM1 60 1.44x44 CCR5 5UIW CCR5 5UIW
TM1 61 1.45x45 CCR5 5UIW CCR9 5LWE
TM1 62 1.46x46 CCR5 5UIW CCR5 5UIW
TM1 63 1.47x47 CCR5 5UIW CCR9 5LWE
TM1 64 1.48x48 CCR5 5UIW CCR9 5LWE
TM1 65 1.49x49 CCR5 5UIW CCR5 5UIW
TM1 66 1.50x50 CCR5 5UIW CCR5 5UIW
TM1 67 1.51x51 CCR5 5UIW CCR9 5LWE
TM1 68 1.52x52 CCR5 5UIW CCR5 5UIW
TM1 69 1.53x53 CCR5 5UIW CCR5 5UIW
TM1 70 1.54x54 CCR5 5UIW CCR5 5UIW
TM1 71 1.55x55 CCR5 5UIW CCR5 5UIW
TM1 72 1.56x56 CCR5 5UIW CCR9 5LWE
TM1 73 1.57x57 CCR5 5UIW CCR9 5LWE
TM1 74 1.58x58 CCR5 5UIW CCR9 5LWE
TM1 75 1.59x59 CCR5 5UIW CCR9 5LWE
TM1 76 1.60x60 CCR5 5UIW CCR9 5LWE
ICL1 77 12.48x48 - - - -
ICL1 78 12.49x49 AT1 receptor 4ZUD β1-adrenoceptor 4AMJ
ICL1 79 12.50x50 AT1 receptor 4ZUD - -
ICL1 80 12.51x51 - - - -
TM2 81 2.37x37 CCR5 5UIW CCR9 5LWE
TM2 82 2.38x38 CCR5 5UIW CCR5 5UIW
TM2 83 2.39x39 CCR5 5UIW CCR5 5UIW
TM2 84 2.40x40 CCR5 5UIW CCR5 5UIW
TM2 85 2.41x41 CCR5 5UIW CCR9 5LWE
TM2 86 2.42x42 CCR5 5UIW CCR9 5LWE
TM2 87 2.43x43 CCR5 5UIW CCR5 5UIW
TM2 88 2.44x44 CCR5 5UIW CCR5 5UIW
TM2 89 2.45x45 CCR5 5UIW CCR5 5UIW
TM2 90 2.46x46 CCR5 5UIW CCR5 5UIW
TM2 91 2.47x47 CCR5 5UIW CCR5 5UIW
TM2 92 2.48x48 CCR5 5UIW CCR5 5UIW
TM2 93 2.49x49 CCR5 5UIW CCR9 5LWE
TM2 94 2.50x50 CCR5 5UIW CCR5 5UIW
TM2 95 2.51x51 CCR5 5UIW CCR5 5UIW
TM2 96 2.52x52 CCR5 5UIW CCR9 5LWE
TM2 97 2.53x53 CCR5 5UIW CCR5 5UIW
TM2 98 2.54x54 CCR5 5UIW CCR5 5UIW
TM2 99 2.55x55 CCR5 5UIW CCR9 5LWE
TM2 100 2.56x56 CCR5 5UIW CCR5 5UIW
TM2 101 2.57x57 CCR5 5UIW CCR9 5LWE
TM2 102 2.58x58 CCR5 5UIW CCR5 5UIW
TM2 103 2.59x59 CCR5 5UIW CCR5 5UIW
TM2 104 2.60x60 CCR5 5UIW CCR5 5UIW
TM2 105 2.61x61 CCR5 5UIW CCR5 5UIW
TM2 106 2.62x62 CCR5 5UIW CCR9 5LWE
TM2 107 2.63x63 CCR5 5UIW CCR9 5LWE
TM2 108 2.64x64 CCR5 5UIW CCR5 5UIW
TM2 109 2.65x65 CCR5 5UIW CCR5 5UIW
TM2 110 2.66x66 CCR5 5UIW US28 5WB1
ECL1 111 23.49x49 CCR5 5UIW CCR5 5UIW
ECL1 112 23.50x50 CCR5 5UIW CCR5 5UIW
ECL1 113 23.51x51 CCR5 5UIW S1P1 receptor 3V2Y
ECL1 114 23.52x52 CCR5 5UIW CCR5 5UIW
TM3 115 3.21x21 CCR5 5UIW - -
TM3 116 3.22x22 CCR5 5UIW apelin receptor 5VBL
TM3 117 3.23x23 CCR5 5UIW CXCR4 3ODU
TM3 118 3.24x24 CCR5 5UIW CCR5 5UIW
TM3 119 3.25x25 CCR5 5UIW CCR5 5UIW
TM3 120 3.26x26 CCR5 5UIW CCR9 5LWE
TM3 121 3.27x27 CCR5 5UIW CCR9 5LWE
TM3 122 3.28x28 CCR5 5UIW CCR9 5LWE
TM3 123 3.29x29 CCR5 5UIW CCR9 5LWE
TM3 124 3.30x30 CCR5 5UIW CCR9 5LWE
TM3 125 3.31x31 CCR5 5UIW CCR9 5LWE
TM3 126 3.32x32 CCR5 5UIW CCR5 5UIW
TM3 127 3.33x33 CCR5 5UIW CCR9 5LWE
TM3 128 3.34x34 CCR5 5UIW CCR9 5LWE
TM3 129 3.35x35 CCR5 5UIW CCR9 5LWE
TM3 130 3.36x36 CCR5 5UIW CCR5 5UIW
TM3 131 3.37x37 CCR5 5UIW CCR9 5LWE
TM3 132 3.38x38 CCR5 5UIW CCR5 5UIW
TM3 133 3.39x39 CCR5 5UIW CCR9 5LWE
TM3 134 3.40x40 CCR5 5UIW CCR9 5LWE
TM3 135 3.41x41 CCR5 5UIW CCR9 5LWE
TM3 136 3.42x42 CCR5 5UIW CCR9 5LWE
TM3 137 3.43x43 CCR5 5UIW CCR5 5UIW
TM3 138 3.44x44 CCR5 5UIW CCR9 5LWE
TM3 139 3.45x45 CCR5 5UIW CCR9 5LWE
TM3 140 3.46x46 CCR5 5UIW CCR9 5LWE
TM3 141 3.47x47 CCR5 5UIW AT1 receptor 4ZUD
TM3 142 3.48x48 CCR5 5UIW CCR9 5LWE
TM3 143 3.49x49 CCR5 5UIW CCR5 5UIW
TM3 144 3.50x50 CCR5 5UIW CCR5 5UIW
TM3 145 3.51x51 CCR5 5UIW CCR5 5UIW
TM3 146 3.52x52 CCR5 5UIW CCR9 5LWE
TM3 147 3.53x53 CCR5 5UIW CCR5 5UIW
TM3 148 3.54x54 CCR5 5UIW CCR9 5LWE
TM3 149 3.55x55 CCR5 5UIW CCR9 5LWE
TM3 150 3.56x56 CCR5 5UIW CCR9 5LWE
ICL2 151 34.50x50 - - - -
ICL2 152 34.51x51 CCR9 5LWE CCR9 5LWE
ICL2 153 34.52x52 CCR9 5LWE CCR9 5LWE
ICL2 154 34.53x53 CCR9 5LWE CCR9 5LWE
ICL2 155 34.54x54 CCR9 5LWE CCR9 5LWE
ICL2 156 34.55x55 CCR9 5LWE CCR9 5LWE
ICL2 157 34.56x56 - - - -
TM4 158 4.35x35 CCR9 5LWE CCR9 5LWE
TM4 159 4.36x36 CCR9 5LWE CCR9 5LWE
TM4 160 4.37x37 CCR9 5LWE CCR9 5LWE
TM4 161 4.38x38 CCR5 5UIW FFA1 receptor 5TZY
TM4 162 4.39x39 CCR5 5UIW CCR9 5LWE
TM4 163 4.40x40 CCR5 5UIW CCR9 5LWE
TM4 164 4.41x41 CCR5 5UIW CCR9 5LWE
TM4 165 4.42x42 CCR5 5UIW CCR9 5LWE
TM4 166 4.43x43 CCR5 5UIW CCR9 5LWE
TM4 167 4.44x44 CCR5 5UIW CCR9 5LWE
TM4 168 4.45x45 CCR5 5UIW CCR9 5LWE
TM4 169 4.46x46 CCR5 5UIW CCR9 5LWE
TM4 170 4.47x47 CCR5 5UIW CCR9 5LWE
TM4 171 4.48x48 CCR5 5UIW CCR9 5LWE
TM4 172 4.49x49 CCR5 5UIW CCR9 5LWE
TM4 173 4.50x50 CCR5 5UIW CCR5 5UIW
TM4 174 4.51x51 CCR5 5UIW CCR5 5UIW
TM4 175 4.52x52 CCR5 5UIW CCR9 5LWE
TM4 176 4.53x53 CCR5 5UIW CCR5 5UIW
TM4 177 4.54x54 CCR5 5UIW CCR9 5LWE
TM4 178 4.55x55 CCR5 5UIW CCR9 5LWE
TM4 179 4.56x56 CCR5 5UIW CCR9 5LWE
TM4 180 4.57x57 CCR5 5UIW CCR9 5LWE
TM4 181 4.58x59 CCR5 5UIW CCR9 5LWE
TM4 182 4.59x60 CCR5 5UIW CCR5 5UIW
TM4 183 4.60x61 CCR5 5UIW CCR9 5LWE
TM4 184 4.61x62 CCR5 5UIW CCR5 5UIW
TM4 185 4.62x63 CCR5 5UIW κ receptor 4DJH
TM4 186 4.63x64 CCR5 5UIW C5a1 receptor 5O9H
TM4 187 4.64x65 CCR5 5UIW NK1 receptor 6HLP
ECL2 188 CCR5 5UIW - -
ECL2 189 CCR5 5UIW - -
ECL2 190 CCR5 5UIW - -
ECL2 191 CCR5 5UIW - -
ECL2 192 CCR5 5UIW CCR5 5UIW
ECL2 193 CCR5 5UIW - -
ECL2 194 CCR5 5UIW - -
ECL2 195 CCR5 5UIW - -
ECL2 196 CCR5 5UIW - -
ECL2 197 CCR5 5UIW - -
ECL2 198 45.50x50 CCR5 5UIW CCR5 5UIW
ECL2 199 45.51x51 CCR5 5UIW μ receptor 4DKL
ECL2 200 45.52x52 CCR5 5UIW apelin receptor 5VBL
ECL2 201 - - - -
ECL2 202 NK1 receptor 6J21 - -
ECL2 203 NK1 receptor 6J21 NK1 receptor 6J21
ECL2 204 NK1 receptor 6J21 - -
ECL2 205 NK1 receptor 6J21 - -
ECL2 206 NK1 receptor 6J21 - -
ECL2 207 NK1 receptor 6J21 - -
ECL2 208 - - - -
TM5 209 5.33x34 CCR5 5UIW - -
TM5 210 5.34x35 CCR5 5UIW AT1 receptor 4ZUD
TM5 211 5.35x36 CCR5 5UIW CCR5 5UIW
TM5 212 5.36x37 CCR5 5UIW MT1 receptor 6ME2
TM5 213 5.37x38 CCR5 5UIW C5a1 receptor 5O9H
TM5 214 5.38x39 CCR5 5UIW C5a1 receptor 5O9H
TM5 215 5.39x40 CCR5 5UIW BLT1 receptor 5X33
TM5 216 5.40x41 CCR5 5UIW Y1 receptor 5ZBH
TM5 217 5.41x42 CCR5 5UIW Y1 receptor 5ZBH
TM5 218 5.42x43 CCR5 5UIW AT1 receptor 4ZUD
TM5 219 5.43x44 CCR5 5UIW CCR5 5UIW
TM5 220 5.44x45 CCR5 5UIW CCR5 5UIW
TM5 221 5.45x46 CCR5 5UIW CCR5 5UIW
TM5 222 5.46x461 CCR5 5UIW CCR5 5UIW
TM5 223 5.47x47 CCR5 5UIW AT1 receptor 4YAY
TM5 224 5.48x48 CCR5 5UIW 5-HT2C receptor 6BQH
TM5 225 5.49x49 CCR5 5UIW CCR5 5UIW
TM5 226 5.50x50 CCR5 5UIW CCR5 5UIW
TM5 227 5.51x51 CCR5 5UIW AT1 receptor 4ZUD
TM5 228 5.52x52 CCR5 5UIW β2-adrenoceptor 5JQH
TM5 229 5.53x53 CCR5 5UIW CCR5 5UIW
TM5 230 5.54x54 CCR5 5UIW CCR5 5UIW
TM5 231 5.55x55 CCR5 5UIW DP2 receptor 6D27
TM5 232 5.56x56 CCR5 5UIW - -
TM5 233 5.57x57 CCR5 5UIW CCR5 5UIW
TM5 234 5.58x58 CCR5 5UIW CCR5 5UIW
TM5 235 5.59x59 CCR5 5UIW AT1 receptor 4ZUD
TM5 236 5.60x60 CCR5 5UIW CXCR4 3ODU
TM5 237 5.61x61 CCR5 5UIW CCR5 5UIW
TM5 238 5.62x62 CCR5 5UIW CXCR4 3ODU
TM5 239 5.63x63 CCR5 5UIW 5-HT2B receptor 4IB4
TM5 240 5.64x64 CCR5 5UIW CCR5 5UIW
TM5 241 5.65x65 CCR5 5UIW CCR5 5UIW
TM5 242 5.66x66 CCR5 5UIW P2Y1 receptor 4XNW
TM5 243 5.67x67 CCR5 5UIW - -
TM5 244 5.68x68 CCR5 6MEO C5a1 receptor 5O9H
ICL3 245 - - - -
ICL3 246 - - - -
ICL3 247 - - - -
ICL3 248 - - - -
TM6 249 6.30x30 CCR5 5UIW CCR9 5LWE
TM6 250 6.31x31 CCR5 5UIW CCR9 5LWE
TM6 251 6.32x32 CCR5 5UIW CCR9 5LWE
TM6 252 6.33x33 CCR5 5UIW CCR9 5LWE
TM6 253 6.34x34 CCR5 5UIW CCR9 5LWE
TM6 254 6.35x35 CCR5 5UIW CCR9 5LWE
TM6 255 6.36x36 CCR5 5UIW CCR2 5T1A
TM6 256 6.37x37 CCR5 5UIW CCR9 5LWE
TM6 257 6.38x38 CCR5 5UIW CCR9 5LWE
TM6 258 6.39x39 CCR5 5UIW CCR5 5UIW
TM6 259 6.40x40 CCR5 5UIW CCR9 5LWE
TM6 260 6.41x41 CCR5 5UIW CCR9 5LWE
TM6 261 6.42x42 CCR5 5UIW CCR9 5LWE
TM6 262 6.43x43 CCR5 5UIW CCR5 5UIW
TM6 263 6.44x44 CCR5 5UIW CCR9 5LWE
TM6 264 6.45x45 CCR5 5UIW CCR9 5LWE
TM6 265 6.46x46 CCR5 5UIW CCR5 5UIW
TM6 266 6.47x47 CCR5 5UIW CCR9 5LWE
TM6 267 6.48x48 CCR5 5UIW CCR9 5LWE
TM6 268 6.49x49 CCR5 5UIW CCR9 5LWE
TM6 269 6.50x50 CCR5 5UIW CCR5 5UIW
TM6 270 6.51x51 CCR5 5UIW CCR5 5UIW
TM6 271 6.52x52 CCR5 5UIW CCR5 5UIW
TM6 272 6.53x53 CCR5 5UIW CCR9 5LWE
TM6 273 6.54x54 CCR5 5UIW CCR9 5LWE
TM6 274 6.55x55 CCR5 5UIW CCR5 5UIW
TM6 275 6.56x56 CCR5 5UIW CCR5 5UIW
TM6 276 6.57x57 CCR5 5UIW CCR9 5LWE
TM6 277 6.58x58 CCR5 5UIW CCR9 5LWE
TM6 278 6.59x59 CCR5 5UIW CCR5 5UIW
TM6 279 6.60x60 CCR5 5UIW CCR9 5LWE
TM6 280 6.61x61 CCR5 5UIW CCR9 5LWE
TM6 281 6.62x62 CCR9 5LWE CCR9 5LWE
TM6 282 6.63x63 CCR9 5LWE CCR9 5LWE
TM6 283 6.64x64 CCR9 5LWE CCR9 5LWE
TM6 284 6.65x65 CCR9 5LWE CCR9 5LWE
ECL3 285 - - - -
ECL3 286 CCR9 5LWE CCR9 5LWE
ECL3 287 - - - -
TM7 288 7.24x23 CCR5 5UIW CCR5 5UIW
TM7 289 7.25x24 CCR5 5UIW CCR5 5UIW
TM7 290 7.26x25 CCR5 5UIW CCR9 5LWE
TM7 291 7.27x26 CCR5 5UIW CCR9 5LWE
TM7 292 7.28x27 CCR5 5UIW CCR5 5UIW
TM7 293 7.29x28 CCR5 5UIW CCR9 5LWE
TM7 294 7.30x29 CCR5 5UIW Y1 receptor 5ZBH
TM7 295 7.31x30 CCR5 5UIW CCR9 5LWE
TM7 296 7.32x31 CCR5 5UIW CCR5 5UIW
TM7 297 7.33x32 CCR5 5UIW CCR9 5LWE
TM7 298 7.34x33 CCR5 5UIW CCR9 5LWE
TM7 299 7.35x34 CCR5 5UIW CCR9 5LWE
TM7 300 7.36x35 CCR5 5UIW CCR5 5UIW
TM7 301 7.37x36 CCR5 5UIW CCR5 5UIW
TM7 302 7.38x37 CCR5 5UIW CCR5 5UIW
TM7 303 7.39x38 CCR5 5UIW CCR9 5LWE
TM7 304 7.40x39 CCR5 5UIW CCR5 5UIW
TM7 305 7.41x40 CCR5 5UIW CCR9 5LWE
TM7 306 7.42x41 CCR5 5UIW CCR9 5LWE
TM7 307 7.43x42 CCR5 5UIW CCR9 5LWE
TM7 308 7.44x43 CCR5 5UIW CCR9 5LWE
TM7 309 7.45x45 CCR5 5UIW CCR5 5UIW
TM7 310 7.46x46 CCR5 5UIW CCR9 5LWE
TM7 311 7.47x47 CCR5 5UIW CCR5 5UIW
TM7 312 7.48x48 CCR5 5UIW CCR9 5LWE
TM7 313 7.49x49 CCR5 5UIW CCR5 5UIW
TM7 314 7.50x50 CCR5 5UIW CCR5 5UIW
TM7 315 7.51x51 CCR5 5UIW CCR9 5LWE
TM7 316 7.52x52 CCR5 5UIW CCR9 5LWE
TM7 317 7.53x53 CCR5 5UIW CCR5 5UIW
TM7 318 7.54x54 CCR5 5UIW CCR9 5LWE
TM7 319 7.55x55 CCR5 5UIW CCR5 5UIW
TM7 320 7.56x56 CCR5 5UIW CCR5 5UIW
H8 321 8.47x47 CCR5 5UIW CCR5 5UIW
H8 322 8.48x48 CCR5 5UIW CCR9 5LWE
H8 323 8.49x49 CCR5 5UIW CCR9 5LWE
H8 324 8.50x50 CCR5 5UIW CCR5 5UIW
H8 325 8.51x51 CCR5 5UIW CCR5 5UIW
H8 326 8.52x52 CCR5 5UIW CCR9 5LWE
H8 327 8.53x53 CCR5 5UIW CCR9 5LWE
H8 328 8.54x54 CCR5 5UIW CCR5 5UIW
H8 329 8.55x55 CCR5 5UIW CCR9 5LWE
H8 330 8.56x56 CCR5 5UIW CCR9 5LWE
H8 331 8.57x57 CCR5 5UIW CCR9 5LWE
H8 332 8.58x58 CCR5 5UIW CCR9 5LWE
H8 333 8.59x59 CCR5 5UIW CCR9 5LWE
H8 334 8.60x60 CCR9 5LWE CCR9 5LWE
H8 335 8.61x61 CCR9 5LWE CCR9 5LWE
H8 336 8.62x62 CCR9 5LWE CCR9 5LWE
H8 337 8.63x63 CCR9 5LWE - -
H8 338 8.64x64 CCR9 5LWE CCR9 5LWE
H8 339 8.65x65 CCR9 5LWE CCR9 5LWE
H8 340 8.66x66 CCR9 5LWE CCR9 5LWE
H8 341 8.67x67 CCR9 5LWE CCR9 5LWE
C-term 342 - - - -
C-term 343 - - - -
C-term 344 - - - -
C-term 345 - - - -
C-term 346 - - - -