GPCRdb

α_2C-adrenoceptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

α_2C-adrenoceptor

SPECIES

Homo sapiens

STATE

Intermediate

VERSION

2021-01-08

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

NGL is a WebGL based 3D viewer powered by MMTF.

MAIN TEMPLATE

5-HT_2B receptor (sequence similarity: 52%) PDB: 4IB4

Align

TEMPLATES

6KUW (α_2C-adrenoceptor)

4IB4 (5-HT_2B receptor)

6K41 (α_2B-adrenoceptor)

6K42 (α_2B-adrenoceptor)

3SN6 (β₂-adrenoceptor)

None

	Main template (%)	Additional templates (%)	No template - freely modelled (%)
Backbone	78.3	12.2	9.5
Side-chains	28.6	57.9	13.5

Number of backbone templates: 5
Number of rotamer templates: 30

Segment	Seq.num.	AA	GPCRdb#	Backbone	PDB	Rotamer	PDB

N-term	42	P		α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
N-term	43	R		α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
N-term	44	G		α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
N-term	45	Q		α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
N-term	46	Y		α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
TM1	47	S	1.28x28	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
TM1	48	A	1.29x29	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
TM1	49	G	1.30x30	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
TM1	50	A	1.31x31	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
TM1	51	V	1.32x32	5-HT_2B receptor	4IB4	M₅ receptor	6OL9
TM1	52	A	1.33x33	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM1	53	G	1.34x34	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM1	54	L	1.35x35	5-HT_2B receptor	4IB4	PAR2	5NDD
TM1	55	A	1.36x36	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	56	A	1.37x37	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	57	V	1.38x38	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM1	58	V	1.39x39	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM1	59	G	1.40x40	5-HT_2B receptor	4IB4	succinate receptor	6RNK
TM1	60	F	1.41x41	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
TM1	61	L	1.42x42	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
TM1	62	I	1.43x43	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	63	V	1.44x44	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM1	64	F	1.45x45	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM1	65	T	1.46x46	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	66	V	1.47x47	5-HT_2B receptor	4IB4	CysLT₂ receptor	6RZ6
TM1	67	V	1.48x48	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM1	68	G	1.49x49	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	69	N	1.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	70	V	1.51x51	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM1	71	L	1.52x52	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	72	V	1.53x53	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	73	V	1.54x54	5-HT_2B receptor	4IB4	succinate receptor	6RNK
TM1	74	I	1.55x55	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM1	75	A	1.56x56	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	76	V	1.57x57	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	77	L	1.58x58	5-HT_2B receptor	4IB4	PAR2	5NDD
TM1	78	T	1.59x59	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM1	79	S	1.60x60	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
ICL1	80	R	12.48x48	-	-	-	-
ICL1	81	A	12.49x49	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ICL1	82	L	12.50x50	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ICL1	83	R	12.51x51	-	-	-	-
TM2	84	A	2.37x37	5-HT_2B receptor	4IB4	PAR2	5NDD
TM2	85	P	2.38x38	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM2	86	Q	2.39x39	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM2	87	N	2.40x40	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	88	L	2.41x41	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM2	89	F	2.42x42	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	90	L	2.43x43	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	91	V	2.44x44	5-HT_2B receptor	4IB4	PAF receptor	5ZKQ
TM2	92	S	2.45x45	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	93	L	2.46x46	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	94	A	2.47x47	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	95	S	2.48x48	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM2	96	A	2.49x49	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	97	D	2.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	98	I	2.51x51	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM2	99	L	2.52x52	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	100	V	2.53x53	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	101	A	2.54x54	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM2	102	T	2.55x55	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM2	103	L	2.56x551	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM2	104	V	2.57x56	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	105	M	2.58x57	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	106	P	2.59x58	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	107	F	2.60x59	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM2	108	S	2.61x60	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM2	109	L	2.62x61	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	110	A	2.63x62	5-HT_2B receptor	4IB4	PAR2	5NDD
TM2	111	N	2.64x63	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM2	112	E	2.65x64	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM2	113	L	2.66x65	5-HT_2B receptor	4IB4	GPR52	6LI1
TM2	114	M	2.67x66	5-HT_2B receptor	4IB4	H₁ receptor	3RZE
TM2	115	A	2.68x67	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ECL1	116	Y	23.49x49	-	-	-	-
ECL1	117	W	23.50x50	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ECL1	118	Y	23.51x51	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ECL1	119	F	23.52x52	-	-	-	-
TM3	120	G	3.21x21	5-HT_2B receptor	4IB4	PAR1	3VW7
TM3	121	Q	3.22x22	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM3	122	V	3.23x23	5-HT_2B receptor	4IB4	5-HT_2B receptor	4NC3
TM3	123	W	3.24x24	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM3	124	C	3.25x25	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	125	G	3.26x26	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM3	126	V	3.27x27	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM3	127	Y	3.28x28	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM3	128	L	3.29x29	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	129	A	3.30x30	5-HT_2B receptor	4IB4	PAR1	3VW7
TM3	130	L	3.31x31	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	131	D	3.32x32	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	132	V	3.33x33	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	133	L	3.34x34	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	134	F	3.35x35	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	135	C	3.36x36	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM3	136	T	3.37x37	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	137	S	3.38x38	5-HT_2B receptor	4IB4	CysLT₂ receptor	6RZ6
TM3	138	S	3.39x39	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	139	I	3.40x40	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	140	V	3.41x41	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM3	141	H	3.42x42	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	142	L	3.43x43	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	143	C	3.44x44	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	144	A	3.45x45	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	145	I	3.46x46	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	146	S	3.47x47	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	147	L	3.48x48	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM3	148	D	3.49x49	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	149	R	3.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	150	Y	3.51x51	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	151	W	3.52x52	5-HT_2B receptor	4IB4	PAR2	5NDD
TM3	152	S	3.53x53	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM3	153	V	3.54x54	5-HT_2B receptor	4IB4	PAR1	3VW7
TM3	154	T	3.55x55	5-HT_2B receptor	4IB4	GPR52	6LI1
TM3	155	Q	3.56x56	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
ICL2	156	A	34.50x50	-	-	-	-
ICL2	157	V	34.51x51	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ICL2	158	E	34.52x52	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ICL2	159	Y	34.53x53	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ICL2	160	N	34.54x54	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ICL2	161	L	34.55x55	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ICL2	162	K	34.56x56	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ICL2	163	R	34.57x57	-	-	-	-
TM4	164	T	4.38x38	5-HT_2B receptor	4IB4	CysLT₁ receptor	6RZ4
TM4	165	P	4.39x39	5-HT_2B receptor	4IB4	GPR52	6LI1
TM4	166	R	4.40x40	5-HT_2B receptor	4IB4	CysLT₂ receptor	6RZ8
TM4	167	R	4.41x41	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM4	168	V	4.42x42	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM4	169	K	4.43x43	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM4	170	A	4.44x44	5-HT_2B receptor	4IB4	TP receptor	6IIV
TM4	171	T	4.45x45	5-HT_2B receptor	4IB4	PAR1	3VW7
TM4	172	I	4.46x46	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM4	173	V	4.47x47	5-HT_2B receptor	4IB4	P2Y₁ receptor	4XNW
TM4	174	A	4.48x48	5-HT_2B receptor	4IB4	PAR1	3VW7
TM4	175	V	4.49x49	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM4	176	W	4.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM4	177	L	4.51x51	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM4	178	I	4.52x52	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM4	179	S	4.53x53	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM4	180	A	4.54x54	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM4	181	V	4.55x55	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM4	182	I	4.56x56	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM4	183	S	4.57x57	α_2B-adrenoceptor	6K41	α_2B-adrenoceptor	6K41
TM4	184	F	4.58x58	α_2B-adrenoceptor	6K41	β₂-adrenoceptor	5JQH
TM4	185	P	4.59x59	α_2B-adrenoceptor	6K41	α_2B-adrenoceptor	6K41
TM4	186	P	4.60x60	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM4	187	L	4.61x61	5-HT_2B receptor	4IB4	PAR1	3VW7
TM4	188	V	4.62x62	5-HT_2B receptor	4IB4	κ receptor	6B73
ECL2	189	S		5-HT_2B receptor	4IB4	-	-
ECL2	190	L		5-HT_2B receptor	4IB4	-	-
ECL2	191	Y		5-HT_2B receptor	4IB4	-	-
ECL2	192	R		-	-	-	-
ECL2	193	Q		-	-	-	-
ECL2	194	P		-	-	-	-
ECL2	195	D		5-HT_2B receptor	4IB4	-	-
ECL2	196	G		5-HT_2B receptor	4IB4	-	-
ECL2	197	A		5-HT_2B receptor	4IB4	-	-
ECL2	198	A		5-HT_2B receptor	4IB4	-	-
ECL2	199	Y		5-HT_2B receptor	4IB4	-	-
ECL2	200	P		5-HT_2B receptor	4IB4	-	-
ECL2	201	Q		-	-	-	-
ECL2	202	C	45.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
ECL2	203	G	45.51x51	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
ECL2	204	L	45.52x52	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
ECL2	205	N		-	-	-	-
ECL2	206	D		-	-	-	-
TM5	207	E	5.35x36	5-HT_2B receptor	4IB4	μ receptor	5C1M
TM5	208	T	5.36x37	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM5	209	W	5.37x38	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM5	210	Y	5.38x39	5-HT_2B receptor	4IB4	PAR2	5NDD
TM5	211	I	5.39x40	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM5	212	L	5.40x41	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM5	213	S	5.41x42	5-HT_2B receptor	4IB4	PAR2	5NDD
TM5	214	S	5.42x43	5-HT_2B receptor	4IB4	PAR1	3VW7
TM5	215	C	5.43x44	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM5	216	I	5.44x45	5-HT_2B receptor	4IB4	PAR2	5NDD
TM5	217	G	5.45x46	5-HT_2B receptor	4IB4	PAR2	5NDD
TM5	218	S	5.46x461	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM5	219	F	5.47x47	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM5	220	F	5.48x48	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM5	221	A	5.49x49	5-HT_2B receptor	4IB4	GPR52	6LI1
TM5	222	P	5.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM5	223	C	5.51x51	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM5	224	L	5.52x52	5-HT_2B receptor	4IB4	P2Y₁₂ receptor	4NTJ
TM5	225	I	5.53x53	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM5	226	M	5.54x54	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM5	227	G	5.55x55	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM5	228	L	5.56x56	5-HT_2B receptor	4IB4	TP receptor	6IIV
TM5	229	V	5.57x57	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM5	230	Y	5.58x58	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM5	231	A	5.59x59	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM5	232	R	5.60x60	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM5	233	I	5.61x61	5-HT_2B receptor	4IB4	PAR1	3VW7
TM5	234	Y	5.62x62	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM5	235	R	5.63x63	5-HT_2B receptor	4IB4	PAR1	3VW7
TM5	236	V	5.64x64	5-HT_2B receptor	4IB4	CysLT₂ receptor	6RZ6
TM5	237	A	5.65x65	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM5	238	K	5.66x66	5-HT_2B receptor	4IB4	succinate receptor	6RNK
TM5	239	L	5.67x67	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM5	240	R	5.68x68	5-HT_2B receptor	4IB4	succinate receptor	6RNK
TM5	241	T	5.69x69	5-HT_2B receptor	4IB4	α_2A-adrenoceptor	6KUX
TM5	242	R	5.70x70	β₂-adrenoceptor	3SN6	M₁ receptor	6OIJ
TM5	243	T	5.71x71	β₂-adrenoceptor	3SN6	-	-
TM5	244	L	5.72x72	β₂-adrenoceptor	3SN6	M₁ receptor	6OIJ
TM5	245	S	5.73x73	β₂-adrenoceptor	3SN6	CB₂ receptor	6PT0
TM5	246	E	5.74x74	β₂-adrenoceptor	3SN6	Rhodopsin	6I9K
TM5	247	K	5.75x75	β₂-adrenoceptor	3SN6	-	-
ICL3	248	R		-	-	-	-
ICL3	249	A		-	-	-	-
ICL3	250	P		-	-	-	-
ICL3	251	V		-	-	-	-
ICL3	252	G		-	-	-	-
ICL3	366	S		-	-	-	-
ICL3	367	V		-	-	-	-
ICL3	368	C		-	-	-	-
ICL3	369	R		-	-	-	-
ICL3	370	R		-	-	-	-
TM6	371	K	6.24x24	α_2B-adrenoceptor	6K42	D₂ receptor	6VMS
TM6	372	V	6.25x25	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	373	A	6.26x26	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	374	Q	6.27x27	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	375	A	6.28x28	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	376	R	6.29x29	5-HT_2B receptor	4IB4	FFA1 receptor	5TZR
TM6	377	E	6.30x30	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	378	K	6.31x31	5-HT_2B receptor	4IB4	PAR1	3VW7
TM6	379	R	6.32x32	5-HT_2B receptor	4IB4	GPR52	6LI0
TM6	380	F	6.33x33	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	381	T	6.34x34	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	382	F	6.35x35	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	383	V	6.36x36	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	384	L	6.37x37	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	385	A	6.38x38	5-HT_2B receptor	4IB4	PAR2	5NDD
TM6	386	V	6.39x39	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM6	387	V	6.40x40	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	388	M	6.41x41	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	389	G	6.42x42	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM6	390	V	6.43x43	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM6	391	F	6.44x44	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	392	V	6.45x45	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM6	393	L	6.46x46	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	394	C	6.47x47	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM6	395	W	6.48x48	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	396	F	6.49x49	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	397	P	6.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	398	F	6.51x51	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	399	F	6.52x52	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	400	F	6.53x53	5-HT_2B receptor	4IB4	P2Y₁₂ receptor	4NTJ
TM6	401	S	6.54x54	5-HT_2B receptor	4IB4	FFA1 receptor	5TZY
TM6	402	Y	6.55x55	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	403	S	6.56x56	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	404	L	6.57x57	5-HT_2B receptor	4IB4	GPR52	6LI1
TM6	405	Y	6.58x58	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM6	406	G	6.59x59	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	407	I	6.60x60	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM6	408	C	6.61x61	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	409	R	6.62x62	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ECL3	410	E		-	-	-	-
ECL3	411	A		α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ECL3	412	C		α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ECL3	413	Q		α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
ECL3	414	V		-	-	-	-
TM7	415	P	7.31x30	5-HT_2B receptor	4IB4	-	-
TM7	416	G	7.32x31	5-HT_2B receptor	4IB4	FFA1 receptor	5TZY
TM7	417	P	7.33x32	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM7	418	L	7.34x33	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	419	F	7.35x34	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM7	420	K	7.36x35	5-HT_2B receptor	4IB4	FFA1 receptor	5TZY
TM7	421	F	7.37x36	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM7	422	F	7.38x37	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	423	F	7.39x38	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM7	424	W	7.40x39	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	425	I	7.41x40	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	426	G	7.42x41	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	427	Y	7.43x42	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	428	C	7.44x43	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM7	429	N	7.45x45	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM7	430	S	7.46x46	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	431	S	7.47x47	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM7	432	L	7.48x48	5-HT_2B receptor	4IB4	P2Y₁₂ receptor	4NTJ
TM7	433	N	7.49x49	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	434	P	7.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	435	V	7.51x51	5-HT_2B receptor	4IB4	GPR52	6LI1
TM7	436	I	7.52x52	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM7	437	Y	7.53x53	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	438	T	7.54x54	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	439	V	7.55x55	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM7	440	F	7.56x56	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
H8	441	N	8.47x47	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
H8	442	Q	8.48x48	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
H8	443	D	8.49x49	5-HT_2B receptor	4IB4	PAR2	5NDD
H8	444	F	8.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
H8	445	R	8.51x51	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
H8	446	R	8.52x52	5-HT_2B receptor	4IB4	TP receptor	6IIV
H8	447	S	8.53x53	5-HT_2B receptor	4IB4	P2Y₁₂ receptor	4NTJ
H8	448	F	8.54x54	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
H8	449	K	8.55x55	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
H8	450	H	8.56x56	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
H8	451	I	8.57x57	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
H8	452	L	8.58x58	5-HT_2B receptor	4IB4	PAR2	5NDD
H8	453	F	8.59x59	α_2C-adrenoceptor	6KUW	α_2C-adrenoceptor	6KUW
C-term	454	R		-	-	-	-
C-term	455	R		-	-	-	-
C-term	456	R		-	-	-	-
C-term	457	R		-	-	-	-
C-term	458	R		-	-	-	-

α2C-adrenoceptor homology model