ADGRA3 homology model

PROTEIN CLASS

Class B2 (Adhesion)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate

VERSION

2020-10-08

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

GLP-1 receptor (sequence similarity: 23%) PDB: 5NX2

TEMPLATES

5UZ7 (CT receptor)
5NX2 (GLP-1 receptor)
6X1A (GLP-1 receptor)
4Z9G (CRF1 receptor)
6M1H (PAC1 receptor)
6WZG (secretin receptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 75.4 5.8 18.8
Side-chains 10.6 19.5 70.0

Number of backbone templates: 6
Number of rotamer templates: 15

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 745 D - - - -
N-term 746 L - - - -
N-term 747 T - - - -
N-term 748 G - - - -
N-term 749 S - - - -
TM1 750 E 1.27x27 CT receptor 5UZ7 - -
TM1 751 L 1.28x28 CT receptor 5UZ7 VPAC1 receptor 6VN7
TM1 752 Y 1.29x29 CT receptor 5UZ7 - -
TM1 753 T 1.30x30 CT receptor 5UZ7 PTH1 receptor 6NBI
TM1 754 Q 1.31x31 CT receptor 5UZ7 VPAC1 receptor 6VN7
TM1 755 A 1.32x32 CT receptor 5UZ7 - -
TM1 756 A 1.33x33 GLP-1 receptor 5NX2 - -
TM1 757 S 1.34x34 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM1 758 L 1.35x35 GLP-1 receptor 5NX2 - -
TM1 759 L 1.36x36 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 760 H 1.37x37 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM1 761 P 1.38x38 GLP-1 receptor 5NX2 - -
TM1 762 V 1.39x39 GLP-1 receptor 5NX2 PAC1 receptor 6P9Y
TM1 763 V 1.40x40 GLP-1 receptor 5NX2 CRF1 receptor 6P9X
TM1 764 Y 1.41x41 GLP-1 receptor 5NX2 CT receptor 6NIY
TM1 765 T 1.42x42 GLP-1 receptor 5NX2 - -
TM1 766 T 1.43x43 GLP-1 receptor 5NX2 calcitonin receptor-like receptor 6UUS
TM1 767 A 1.44x44 GLP-1 receptor 5NX2 - -
TM1 768 I 1.45x45 GLP-1 receptor 5NX2 calcitonin receptor-like receptor 6UUS
TM1 769 I 1.46x46 GLP-1 receptor 5NX2 - -
TM1 770 L 1.47x47 GLP-1 receptor 5NX2 - -
TM1 771 L 1.48x48 GLP-1 receptor 5NX2 - -
TM1 772 L 1.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 773 C 1.50x50 GLP-1 receptor 5NX2 - -
TM1 774 L 1.51x51 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM1 775 L 1.52x52 GLP-1 receptor 5NX2 - -
TM1 776 A 1.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 777 V 1.54x54 GLP-1 receptor 5NX2 - -
TM1 778 I 1.55x55 GLP-1 receptor 5NX2 - -
TM1 779 V 1.56x56 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM1 780 S 1.57x57 GLP-1 receptor 5NX2 CT receptor 6NIY
TM1 781 Y 1.58x58 GLP-1 receptor 5NX2 - -
TM1 782 I 1.59x59 GLP-1 receptor 5NX2 - -
TM1 783 Y 1.60x60 GLP-1 receptor 5NX2 - -
TM1 784 H 1.61x61 GLP-1 receptor 5NX2 - -
TM1 785 H 1.62x62 GLP-1 receptor 5NX2 - -
TM1 786 S 1.63x63 GLP-1 receptor 5NX2 - -
TM1 787 L 1.64x64 GLP-1 receptor 5NX2 CRF1 receptor 6P9X
ICL1 788 I - - - -
ICL1 789 R - - - -
TM2 790 I 2.44x44 GLP-1 receptor 5NX2 - -
TM2 791 S 2.45x45 GLP-1 receptor 5NX2 - -
TM2 792 L 2.46x46 GLP-1 receptor 5NX2 - -
TM2 793 K 2.47x47 GLP-1 receptor 5NX2 - -
TM2 794 S 2.48x48 GLP-1 receptor 5NX2 - -
TM2 795 W 2.49x49 GLP-1 receptor 5NX2 - -
TM2 796 H 2.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 797 M 2.51x51 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM2 798 L 2.52x52 GLP-1 receptor 5NX2 - -
TM2 799 V 2.53x53 GLP-1 receptor 5NX2 - -
TM2 800 N 2.54x54 GLP-1 receptor 5NX2 - -
TM2 801 L 2.55x55 GLP-1 receptor 5NX2 CT receptor 6NIY
TM2 802 C 2.56x56 GLP-1 receptor 5NX2 - -
TM2 803 F 2.57x57 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 804 H 2.58x58 GLP-1 receptor 5NX2 - -
TM2 805 I 2.59x59 GLP-1 receptor 5NX2 - -
TM2 806 F 2.60x60 GLP-1 receptor 5NX2 - -
TM2 807 L 2.61x61 GLP-1 receptor 5NX2 - -
TM2 808 T 2.62x62 GLP-1 receptor 5NX2 - -
TM2 809 C 2.63x63 GLP-1 receptor 5NX2 GLP-1 receptor 5VEW
TM2 810 V 2.64x64 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 811 V 2.65x65 GLP-1 receptor 5NX2 - -
TM2 812 F 2.66x66 GLP-1 receptor 5NX2 glucagon receptor 5EE7
TM2 813 V 2.67x67 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM2 814 G 2.68x68 GLP-1 receptor 5NX2 - -
TM2 815 G 2.69x69 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM2 816 I 2.70x70 GLP-1 receptor 5NX2 PAC1 receptor 6P9Y
ECL1 817 T - - - -
ECL1 818 Q - - - -
ECL1 819 T - - - -
ECL1 820 R - - - -
ECL1 821 N - - - -
ECL1 822 A - - - -
TM3 823 S 3.27x27 GLP-1 receptor 5NX2 - -
TM3 824 I 3.28x28 GLP-1 receptor 5NX2 - -
TM3 825 C 3.29x29 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 826 Q 3.30x30 GLP-1 receptor 5NX2 - -
TM3 827 A 3.31x31 GLP-1 receptor 5NX2 PAC1 receptor 6P9Y
TM3 828 V 3.32x32 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 829 G 3.33x33 GLP-1 receptor 5NX2 - -
TM3 830 I 3.34x34 GLP-1 receptor 5NX2 - -
TM3 831 I 3.35x35 GLP-1 receptor 5NX2 CRF2 receptor 6PB1
TM3 832 L 3.36x36 GLP-1 receptor 5NX2 - -
TM3 833 H 3.37x37 GLP-1 receptor 5NX2 PAC1 receptor 6P9Y
TM3 834 Y 3.38x38 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 835 S 3.39x39 GLP-1 receptor 5NX2 - -
TM3 836 T 3.40x40 GLP-1 receptor 5NX2 - -
TM3 837 L 3.41x41 GLP-1 receptor 5NX2 - -
TM3 838 A 3.42x42 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 839 T 3.43x43 GLP-1 receptor 5NX2 - -
TM3 840 V 3.44x44 GLP-1 receptor 5NX2 - -
TM3 841 L 3.45x45 GLP-1 receptor 5NX2 - -
TM3 842 W 3.46x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 843 V 3.47x47 GLP-1 receptor 5NX2 - -
TM3 844 G 3.48x48 GLP-1 receptor 5NX2 - -
TM3 845 V 3.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 846 T 3.50x50 GLP-1 receptor 5NX2 - -
TM3 847 A 3.51x51 GLP-1 receptor 5NX2 - -
TM3 848 R 3.52x52 GLP-1 receptor 5NX2 - -
TM3 849 N 3.53x53 GLP-1 receptor 5NX2 - -
TM3 850 I 3.54x54 GLP-1 receptor 5NX2 - -
TM3 851 Y 3.55x55 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 852 K 3.56x56 GLP-1 receptor 5NX2 - -
TM3 853 Q 3.57x57 GLP-1 receptor 5NX2 - -
TM3 854 V 3.58x58 GLP-1 receptor 5NX2 - -
TM3 855 T 3.59x59 GLP-1 receptor 5NX2 - -
TM3 856 K 3.60x60 GLP-1 receptor 5NX2 - -
ICL2 857 K - - - -
ICL2 858 A - - - -
ICL2 859 K - - - -
ICL2 860 R - - - -
ICL2 861 C - - - -
ICL2 862 Q - - - -
ICL2 863 D - - - -
ICL2 864 P - - - -
ICL2 865 D - - - -
ICL2 866 E - - - -
ICL2 867 P - - - -
ICL2 868 P - - - -
ICL2 869 P - - - -
ICL2 870 P - - - -
ICL2 871 P - - - -
TM4 872 R 4.40x41 GLP-1 receptor 5NX2 PAC1 receptor 6P9Y
TM4 873 P 4.41x42 GLP-1 receptor 5NX2 - -
TM4 874 M 4.42x43 GLP-1 receptor 5NX2 - -
TM4 875 L 4.43x44 GLP-1 receptor 5NX2 - -
TM4 876 R 4.44x45 GLP-1 receptor 5NX2 - -
TM4 877 F 4.45x46 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM4 878 Y 4.46x47 GLP-1 receptor 5NX2 CT receptor 6NIY
TM4 879 L 4.47x48 GLP-1 receptor 5NX2 CT receptor 6NIY
TM4 880 I 4.48x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 881 G 4.49x491 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 882 G 4.50x50 GLP-1 receptor 5NX2 - -
TM4 883 G 4.51x51 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 884 I 4.52x52 GLP-1 receptor 5NX2 CRF2 receptor 6PB1
TM4 885 P 4.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 886 I 4.54x54 GLP-1 receptor 5NX2 - -
TM4 887 I 4.55x55 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM4 888 V 4.56x56 GLP-1 receptor 5NX2 - -
TM4 889 C 4.57x57 GLP-1 receptor 5NX2 - -
TM4 890 G 4.58x58 GLP-1 receptor 5NX2 - -
TM4 891 I 4.59x59 GLP-1 receptor 5NX2 CT receptor 6NIY
TM4 892 T 4.60x60 GLP-1 receptor 5NX2 - -
TM4 893 A 4.61x61 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM4 894 A 4.62x62 GLP-1 receptor 5NX2 - -
TM4 895 A 4.63x63 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM4 896 N 4.64x64 GLP-1 receptor 5NX2 - -
TM4 897 I 4.65x65 GLP-1 receptor 5NX2 VPAC1 receptor 6VN7
TM4 898 K 4.66x66 GLP-1 receptor 5NX2 - -
TM4 899 N 4.67x67 GLP-1 receptor 5NX2 - -
TM4 900 Y 4.68x68 CRF1 receptor 4Z9G calcitonin receptor-like receptor 6UUS
ECL2 901 G - - - -
ECL2 902 S - - - -
ECL2 903 R - - - -
ECL2 904 P - - - -
ECL2 905 N - - - -
ECL2 906 A - - - -
ECL2 907 P - - - -
ECL2 908 Y - - - -
ECL2 909 C 45.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ECL2 910 W 45.51x51 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ECL2 911 M 45.52x52 GLP-1 receptor 5NX2 - -
ECL2 912 A - - - -
TM5 913 W 5.32x32 - - - -
TM5 914 E 5.33x33 GLP-1 receptor 5NX2 - -
TM5 915 P 5.34x34 GLP-1 receptor 5NX2 - -
TM5 916 S 5.35x35 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM5 917 L 5.36x36 GLP-1 receptor 5NX2 PAC1 receptor 6P9Y
TM5 918 G 5.37x37 GLP-1 receptor 5NX2 - -
TM5 919 A 5.38x38 GLP-1 receptor 5NX2 - -
TM5 920 F 5.39x39 GLP-1 receptor 5NX2 - -
TM5 921 Y 5.40x40 GLP-1 receptor 5NX2 - -
TM5 922 G 5.41x41 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM5 923 P 5.42x42 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 924 A 5.43x43 GLP-1 receptor 5NX2 - -
TM5 925 S 5.44x44 GLP-1 receptor 5NX2 - -
TM5 926 F 5.45x45 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 927 I 5.46x46 GLP-1 receptor 5NX2 - -
TM5 928 T 5.47x47 GLP-1 receptor 5NX2 - -
TM5 929 F 5.48x48 GLP-1 receptor 5NX2 - -
TM5 930 V 5.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 931 N 5.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 932 C 5.51x51 GLP-1 receptor 5NX2 - -
TM5 933 M 5.52x52 GLP-1 receptor 5NX2 - -
TM5 934 Y 5.53x53 GLP-1 receptor 5NX2 - -
TM5 935 F 5.54x54 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 936 L 5.55x55 GLP-1 receptor 5NX2 CT receptor 6NIY
TM5 937 S 5.56x56 GLP-1 receptor 5NX2 - -
TM5 938 I 5.57x57 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM5 939 F 5.58x58 GLP-1 receptor 5NX2 - -
TM5 940 I 5.59x59 GLP-1 receptor 5NX2 - -
TM5 941 Q 5.60x60 GLP-1 receptor 5NX2 - -
TM5 942 L 5.61x61 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM5 943 K 5.62x62 GLP-1 receptor 5NX2 - -
TM5 944 R 5.63x63 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM5 945 H 5.64x64 GLP-1 receptor 5NX2 - -
TM5 946 P 5.65x65 GLP-1 receptor 5NX2 - -
ICL3 947 E - - - -
ICL3 948 R - - - -
ICL3 949 K - - - -
ICL3 950 Y - - - -
ICL3 951 E - - - -
ICL3 986 L - - - -
ICL3 987 E - - - -
ICL3 988 N - - - -
ICL3 989 E - - - -
ICL3 990 H - - - -
TM6 991 T 6.34x34 GLP-1 receptor 5NX2 - -
TM6 992 F 6.35x35 GLP-1 receptor 5NX2 - -
TM6 993 H 6.36x36 GLP-1 receptor 5NX2 - -
TM6 994 S 6.37x37 GLP-1 receptor 5NX2 - -
TM6 995 Q 6.38x38 GLP-1 receptor 5NX2 - -
TM6 996 L 6.39x39 GLP-1 receptor 5NX2 PTH1 receptor 6NBI
TM6 997 L 6.40x40 GLP-1 receptor 5NX2 - -
TM6 998 G 6.41x41 GLP-1 receptor 5NX2 - -
TM6 999 A 6.42x42 GLP-1 receptor 5NX2 - -
TM6 1000 S 6.43x43 GLP-1 receptor 5NX2 - -
TM6 1001 L 6.44x44 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM6 1002 T 6.45x45 GLP-1 receptor 5NX2 - -
TM6 1003 L 6.46x46 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM6 1004 L 6.47x47 GLP-1 receptor 5NX2 - -
TM6 1005 L 6.48x48 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 1006 Y 6.49x49 GLP-1 receptor 5NX2 - -
TM6 1007 V 6.50x50 GLP-1 receptor 5NX2 - -
TM6 1008 A 6.51x51 GLP-1 receptor 5NX2 - -
TM6 1009 L 6.52x52 GLP-1 receptor 5NX2 - -
TM6 1010 W 6.53x53 GLP-1 receptor 5NX2 - -
TM6 1011 M 6.54x54 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM6 1012 F 6.55x55 GLP-1 receptor 5NX2 - -
TM6 1013 G 6.56x56 GLP-1 receptor 5NX2 - -
TM6 1014 A 6.57x57 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 1015 L 6.58x58 GLP-1 receptor 5NX2 PTH1 receptor 6FJ3
TM6 1016 A 6.59x59 PAC1 receptor 6M1H - -
ECL3 1017 V - - - -
ECL3 1018 S GLP-1 receptor 6X1A - -
ECL3 1019 L GLP-1 receptor 6X1A - -
ECL3 1020 Y GLP-1 receptor 6X1A - -
ECL3 1021 Y - - - -
TM7 1022 P 7.33x32 GLP-1 receptor 5NX2 - -
TM7 1023 L 7.34x33 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 1024 D 7.35x34 GLP-1 receptor 5NX2 - -
TM7 1025 L 7.36x35 GLP-1 receptor 5NX2 - -
TM7 1026 V 7.37x36 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM7 1027 F 7.38x37 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM7 1028 S 7.39x38 GLP-1 receptor 5NX2 - -
TM7 1029 F 7.40x39 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 1030 V 7.41x40 GLP-1 receptor 5NX2 CT receptor 6NIY
TM7 1031 F 7.42x41 GLP-1 receptor 5NX2 - -
TM7 1032 G 7.43x42 GLP-1 receptor 5NX2 - -
TM7 1033 A 7.44x43 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM7 1034 T 7.45x44 GLP-1 receptor 5NX2 - -
TM7 1035 S 7.46x45 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM7 1036 L 7.47x46 GLP-1 receptor 5NX2 - -
TM7 1037 S 7.48x47 GLP-1 receptor 5NX2 - -
TM7 1038 F 7.49x49 GLP-1 receptor 5NX2 - -
TM7 1039 S 7.50x50 GLP-1 receptor 5NX2 - -
TM7 1040 A 7.51x51 GLP-1 receptor 5NX2 - -
TM7 1041 F 7.52x52 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM7 1042 F 7.53x53 GLP-1 receptor 5NX2 - -
TM7 1043 V 7.54x54 GLP-1 receptor 5NX2 - -
TM7 1044 V 7.55x55 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM7 1045 H 7.56x56 GLP-1 receptor 5NX2 - -
TM7 1046 H 7.57x57 GLP-1 receptor 5NX2 - -
TM7 1047 C 7.58x58 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 1048 V 7.59x59 GLP-1 receptor 5NX2 - -
TM7 1049 N 7.60x60 GLP-1 receptor 5NX2 - -
H8 1050 R 8.47x47 GLP-1 receptor 5NX2 - -
H8 1051 E 8.48x48 GLP-1 receptor 5NX2 - -
H8 1052 D 8.49x49 GLP-1 receptor 5NX2 - -
H8 1053 V 8.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
H8 1054 R 8.51x51 GLP-1 receptor 5NX2 CRF1 receptor 6P9X
H8 1055 L 8.52x52 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
H8 1056 A 8.53x53 GLP-1 receptor 5NX2 CRF1 receptor 6P9X
H8 1057 W 8.54x54 GLP-1 receptor 5NX2 - -
H8 1058 I 8.55x55 GLP-1 receptor 5NX2 - -
H8 1059 M 8.56x56 GLP-1 receptor 5NX2 - -
H8 1060 T 8.57x57 GLP-1 receptor 5NX2 - -
H8 1061 C 8.58x58 secretin receptor 6WZG - -
H8 1062 C 8.59x59 secretin receptor 6WZG - -
H8 1063 P 8.60x60 secretin receptor 6WZG - -
H8 1064 G 8.61x61 secretin receptor 6WZG - -
H8 1065 R 8.62x62 secretin receptor 6WZG GLP-1 receptor 5VAI
H8 1066 S 8.63x63 secretin receptor 6WZG - -
C-term 1067 S - - - -
C-term 1068 Y - - - -
C-term 1069 S - - - -
C-term 1070 V - - - -
C-term 1071 Q - - - -