ADGRB1 homology model

PROTEIN CLASS

Class B2 (Adhesion)

RECEPTOR

ADGRB1

SPECIES

Homo sapiens

STATE

Intermediate

VERSION

2021-11-02

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

GLP-1 receptor (sequence similarity: 7%) PDB: 5NX2
Align

TEMPLATES

5NX2 (GLP-1 receptor)
4Z9G (CRF1 receptor)
6PB0 (CRF1 receptor)
7D77 (ADGRG3)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 81.3 3.7 15.0
Side-chains 19.4 33.3 47.3

Number of backbone templates: 4
Number of rotamer templates: 18

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 937 A - GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
N-term 938 D - GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
N-term 939 A - GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
N-term 940 N - GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
N-term 941 M - GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 942 E 1.34x34 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 943 K 1.35x35 GLP-1 receptor 5NX2 - -
TM1 944 A 1.36x36 GLP-1 receptor 5NX2 CT receptor 6NIY
TM1 945 T 1.37x37 GLP-1 receptor 5NX2 - -
TM1 946 L 1.38x38 GLP-1 receptor 5NX2 - -
TM1 947 P 1.39x39 GLP-1 receptor 5NX2 - -
TM1 948 S 1.40x40 GLP-1 receptor 5NX2 - -
TM1 949 V 1.41x41 GLP-1 receptor 5NX2 CRF2 receptor 6PB1
TM1 950 T 1.42x42 GLP-1 receptor 5NX2 - -
TM1 951 L 1.43x43 GLP-1 receptor 5NX2 - -
TM1 952 I 1.44x44 GLP-1 receptor 5NX2 CT receptor 6NIY
TM1 953 V 1.45x45 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 954 G 1.46x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 955 C 1.47x47 GLP-1 receptor 5NX2 ADGRG3 7D77
TM1 956 G 1.48x48 GLP-1 receptor 5NX2 calcitonin receptor-like receptor 6UVA
TM1 957 V 1.49x49 GLP-1 receptor 5NX2 CRF2 receptor 6PB1
TM1 958 S 1.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 959 S 1.51x51 GLP-1 receptor 5NX2 - -
TM1 960 L 1.52x52 GLP-1 receptor 5NX2 - -
TM1 961 T 1.53x53 GLP-1 receptor 5NX2 CT receptor 6NIY
TM1 962 L 1.54x54 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 963 L 1.55x55 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM1 964 M 1.56x56 GLP-1 receptor 5NX2 - -
TM1 965 L 1.57x57 GLP-1 receptor 5NX2 - -
TM1 966 V 1.58x58 GLP-1 receptor 5NX2 PTH1 receptor 6FJ3
TM1 967 I 1.59x59 GLP-1 receptor 5NX2 ADGRG3 7D77
TM1 968 I 1.60x60 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 969 Y 1.61x61 GLP-1 receptor 5NX2 ADGRG3 7D77
TM1 970 V 1.62x62 GLP-1 receptor 5NX2 CT receptor 6NIY
TM1 971 S 1.63x63 GLP-1 receptor 5NX2 - -
TM1 972 V 1.64x64 GLP-1 receptor 5NX2 - -
ICL1 973 W - - - - -
ICL1 974 R 12.48x48 CRF1 receptor 4Z9G CRF1 receptor 4Z9G
ICL1 975 Y 12.49x49 CRF1 receptor 4Z9G - -
ICL1 976 I 12.50x50 CRF1 receptor 4Z9G CRF1 receptor 4Z9G
ICL1 977 R 12.51x51 - - - -
TM2 978 S 2.44x44 GLP-1 receptor 5NX2 - -
TM2 979 E 2.45x45 GLP-1 receptor 5NX2 - -
TM2 980 R 2.46x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 981 S 2.47x47 GLP-1 receptor 5NX2 - -
TM2 982 V 2.48x48 GLP-1 receptor 5NX2 CRF2 receptor 6PB1
TM2 983 I 2.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 984 L 2.50x50 GLP-1 receptor 5NX2 - -
TM2 985 I 2.51x51 GLP-1 receptor 5NX2 GIP receptor 7DTY
TM2 986 N 2.52x52 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 987 F 2.53x53 GLP-1 receptor 5NX2 - -
TM2 988 C 2.54x54 GLP-1 receptor 5NX2 - -
TM2 989 L 2.55x55 GLP-1 receptor 5NX2 CT receptor 6NIY
TM2 990 S 2.56x56 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 991 I 2.57x57 GLP-1 receptor 5NX2 - -
TM2 992 I 2.58x58 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 993 S 2.59x59 GLP-1 receptor 5NX2 - -
TM2 994 S 2.60x60 GLP-1 receptor 5NX2 - -
TM2 995 N 2.61x61 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM2 996 A 2.62x62 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM2 997 L 2.63x63 GLP-1 receptor 5NX2 - -
TM2 998 I 2.64x64 GLP-1 receptor 5NX2 CT receptor 6NIY
TM2 999 L 2.65x65 GLP-1 receptor 5NX2 ADGRG3 7D77
TM2 1000 I 2.66x66 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 1001 G 2.67x67 GLP-1 receptor 5NX2 - -
TM2 1002 Q 2.68x68 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM2 1003 T 2.69x69 GLP-1 receptor 5NX2 calcitonin receptor-like receptor 6UVA
TM2 1004 Q 2.70x70 GLP-1 receptor 5NX2 - -
ECL1 1005 T - - - - -
ECL1 1006 R - - - - -
ECL1 1007 N - - - - -
ECL1 1008 K - - - - -
TM3 1009 V 3.27x27 GLP-1 receptor 5NX2 CRF2 receptor 6PB1
TM3 1010 V 3.28x28 GLP-1 receptor 5NX2 - -
TM3 1011 C 3.29x29 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 1012 T 3.30x30 GLP-1 receptor 5NX2 - -
TM3 1013 L 3.31x31 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 1014 V 3.32x32 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 1015 A 3.33x33 GLP-1 receptor 5NX2 glucagon receptor 5YQZ
TM3 1016 A 3.34x34 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM3 1017 F 3.35x35 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 1018 L 3.36x36 GLP-1 receptor 5NX2 GLP-2 receptor 7D68
TM3 1019 H 3.37x37 GLP-1 receptor 5NX2 ADGRG3 7D77
TM3 1020 F 3.38x38 GLP-1 receptor 5NX2 GHRH receptor 7CZ5
TM3 1021 F 3.39x39 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM3 1022 F 3.40x40 GLP-1 receptor 5NX2 - -
TM3 1023 L 3.41x41 GLP-1 receptor 5NX2 ADGRG3 7D77
TM3 1024 S 3.42x42 GLP-1 receptor 5NX2 PAC1 receptor 6P9Y
TM3 1025 S 3.43x43 GLP-1 receptor 5NX2 - -
TM3 1026 F 3.44x44 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM3 1027 C 3.45x45 GLP-1 receptor 5NX2 glucagon receptor 5YQZ
TM3 1028 W 3.46x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 1029 V 3.47x47 GLP-1 receptor 5NX2 - -
TM3 1030 L 3.48x48 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 1031 T 3.49x49 GLP-1 receptor 5NX2 - -
TM3 1032 E 3.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 1033 A 3.51x51 GLP-1 receptor 5NX2 ADGRG3 7D77
TM3 1034 W 3.52x52 GLP-1 receptor 5NX2 - -
TM3 1035 Q 3.53x53 GLP-1 receptor 5NX2 - -
TM3 1036 S 3.54x54 GLP-1 receptor 5NX2 - -
TM3 1037 Y 3.55x55 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 1038 M 3.56x56 GLP-1 receptor 5NX2 - -
TM3 1039 A 3.57x57 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM3 1040 V 3.58x58 GLP-1 receptor 5NX2 - -
TM3 1041 T 3.59x59 GLP-1 receptor 5NX2 - -
TM3 1042 G 3.60x60 GLP-1 receptor 5NX2 - -
ICL2 1043 H - - - - -
ICL2 1044 L - - - - -
ICL2 1045 R - - - - -
ICL2 1046 N - - - - -
ICL2 1047 R - - - - -
TM4 1048 L 4.40x41 GLP-1 receptor 5NX2 - -
TM4 1049 I 4.41x42 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 1050 R 4.42x43 GLP-1 receptor 5NX2 - -
TM4 1051 K 4.43x44 GLP-1 receptor 5NX2 GLP-1 receptor 5VAI
TM4 1052 R 4.44x45 GLP-1 receptor 5NX2 GLP-2 receptor 7D68
TM4 1053 F 4.45x46 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM4 1054 L 4.46x47 GLP-1 receptor 5NX2 CRF2 receptor 6PB1
TM4 1055 C 4.47x48 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM4 1056 L 4.48x49 GLP-1 receptor 5NX2 CT receptor 6NIY
TM4 1057 G 4.49x491 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 1058 W 4.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 1059 G 4.51x51 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 1060 L 4.52x52 GLP-1 receptor 5NX2 ADGRG3 7D77
TM4 1061 P 4.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 1062 A 4.54x54 GLP-1 receptor 5NX2 ADGRG3 7D77
TM4 1063 L 4.55x55 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 1064 V 4.56x56 GLP-1 receptor 5NX2 - -
TM4 1065 V 4.57x57 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 1066 A 4.58x58 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM4 1067 I 4.59x59 GLP-1 receptor 5NX2 CT receptor 6NIY
TM4 1068 S 4.60x60 GLP-1 receptor 5NX2 - -
TM4 1069 V 4.61x61 GLP-1 receptor 5NX2 GHRH receptor 7CZ5
TM4 1070 G 4.62x62 GLP-1 receptor 5NX2 - -
TM4 1071 F 4.63x63 GLP-1 receptor 5NX2 - -
TM4 1072 T 4.64x64 GLP-1 receptor 5NX2 - -
ECL2 1073 K - - - - -
ECL2 1074 A - - - - -
ECL2 1075 K - - - - -
ECL2 1076 G - - - - -
ECL2 1077 Y - - - - -
ECL2 1078 S - - - - -
ECL2 1079 T - - - - -
ECL2 1080 M - - - - -
ECL2 1081 N - - - - -
ECL2 1082 Y - - - - -
ECL2 1083 C 45.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ECL2 1084 W 45.51x51 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ECL2 1085 L 45.52x52 GLP-1 receptor 5NX2 CT receptor 6NIY
ECL2 1086 S - GLP-1 receptor 5NX2 - -
ECL2 1087 L - GLP-1 receptor 5NX2 - -
ECL2 1088 E - GLP-1 receptor 5NX2 - -
TM5 1089 G 5.33x33 GLP-1 receptor 5NX2 - -
TM5 1090 G 5.34x34 GLP-1 receptor 5NX2 PTH2 receptor 7F16
TM5 1091 L 5.35x35 GLP-1 receptor 5NX2 - -
TM5 1092 L 5.36x36 GLP-1 receptor 5NX2 calcitonin receptor-like receptor 6UVA
TM5 1093 Y 5.37x37 GLP-1 receptor 5NX2 ADGRG3 7D77
TM5 1094 A 5.38x38 GLP-1 receptor 5NX2 - -
TM5 1095 F 5.39x39 GLP-1 receptor 5NX2 - -
TM5 1096 V 5.40x40 GLP-1 receptor 5NX2 - -
TM5 1097 G 5.41x41 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM5 1098 P 5.42x42 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1099 A 5.43x43 GLP-1 receptor 5NX2 - -
TM5 1100 A 5.44x44 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM5 1101 A 5.45x45 GLP-1 receptor 5NX2 CT receptor 6NIY
TM5 1102 V 5.46x46 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM5 1103 V 5.47x47 GLP-1 receptor 5NX2 GHRH receptor 7CZ5
TM5 1104 L 5.48x48 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM5 1105 V 5.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1106 N 5.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1107 M 5.51x51 GLP-1 receptor 5NX2 ADGRG3 7D77
TM5 1108 V 5.52x52 GLP-1 receptor 5NX2 CRF2 receptor 6PB1
TM5 1109 I 5.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1110 G 5.54x54 GLP-1 receptor 5NX2 - -
TM5 1111 I 5.55x55 GLP-1 receptor 5NX2 VPAC1 receptor 6VN7
TM5 1112 L 5.56x56 GLP-1 receptor 5NX2 ADGRG3 7D77
TM5 1113 V 5.57x57 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1114 F 5.58x58 GLP-1 receptor 5NX2 - -
TM5 1115 N 5.59x59 GLP-1 receptor 5NX2 - -
TM5 1116 K 5.60x60 GLP-1 receptor 5NX2 ADGRG3 7D77
TM5 1117 L 5.61x61 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM5 1118 V 5.62x62 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1119 S 5.63x63 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1120 K 5.64x64 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1121 D 5.65x65 GLP-1 receptor 5NX2 - -
ICL3 1122 G - - - - -
ICL3 1123 I - - - - -
ICL3 1124 T - - - - -
ICL3 1125 D - - - - -
ICL3 1126 K - - - - -
ICL3 1127 K - - - - -
ICL3 1128 L - - - - -
ICL3 1129 K - - - - -
ICL3 1130 E - - - - -
TM6 1131 R 6.34x34 GLP-1 receptor 5NX2 - -
TM6 1132 A 6.35x35 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM6 1133 G 6.36x36 GLP-1 receptor 5NX2 - -
TM6 1134 A 6.37x37 GLP-1 receptor 5NX2 - -
TM6 1135 S 6.38x38 GLP-1 receptor 5NX2 - -
TM6 1136 L 6.39x39 GLP-1 receptor 5NX2 PTH1 receptor 6NBI
TM6 1137 W 6.40x40 GLP-1 receptor 5NX2 - -
TM6 1138 S 6.41x41 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 1139 S 6.42x42 GLP-1 receptor 5NX2 - -
TM6 1140 C 6.43x43 GLP-1 receptor 5NX2 - -
TM6 1141 V 6.44x44 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM6 1142 V 6.45x45 GLP-1 receptor 5NX2 - -
TM6 1143 L 6.46x46 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM6 1144 P 6.47x47 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM6 1145 L 6.48x48 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 1146 L 6.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 1147 A 6.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 1148 L 6.51x51 GLP-1 receptor 5NX2 - -
TM6 1149 T 6.52x52 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM6 1150 W 6.53x53 GLP-1 receptor 5NX2 ADGRG3 7D77
TM6 1151 M 6.54x54 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM6 1152 S 6.55x55 GLP-1 receptor 5NX2 - -
TM6 1153 A 6.56x56 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM6 1154 V 6.57x57 GLP-1 receptor 5NX2 PTH2 receptor 7F16
TM6 1155 L 6.58x58 GLP-1 receptor 5NX2 PTH1 receptor 6FJ3
ECL3 1156 A - - - - -
ECL3 1157 V - - - - -
ECL3 1158 T - - - - -
ECL3 1159 D - - - - -
ECL3 1160 R - - - - -
ECL3 1161 R - - - - -
TM7 1162 S 7.35x34 GLP-1 receptor 5NX2 - -
TM7 1163 A 7.36x35 GLP-1 receptor 5NX2 - -
TM7 1164 L 7.37x36 GLP-1 receptor 5NX2 - -
TM7 1165 F 7.38x37 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM7 1166 Q 7.39x38 GLP-1 receptor 5NX2 - -
TM7 1167 I 7.40x39 GLP-1 receptor 5NX2 - -
TM7 1168 L 7.41x40 GLP-1 receptor 5NX2 GHRH receptor 7CZ5
TM7 1169 F 7.42x41 GLP-1 receptor 5NX2 ADGRG3 7D77
TM7 1170 A 7.43x42 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM7 1171 V 7.44x43 GLP-1 receptor 5NX2 VPAC1 receptor 6VN7
TM7 1172 F 7.45x44 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 1173 D 7.46x45 GLP-1 receptor 5NX2 - -
TM7 1174 S 7.47x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 1175 L 7.48x47 GLP-1 receptor 5NX2 ADGRG3 7D77
TM7 1176 E 7.49x49 GLP-1 receptor 5NX2 - -
TM7 1177 G 7.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 1178 F 7.51x51 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM7 1179 V 7.52x52 GLP-1 receptor 5NX2 VPAC1 receptor 6VN7
TM7 1180 I 7.53x53 GLP-1 receptor 5NX2 ADGRG3 7D77
TM7 1181 V 7.54x54 GLP-1 receptor 5NX2 - -
TM7 1182 M 7.55x55 GLP-1 receptor 5NX2 - -
TM7 1183 V 7.56x56 GLP-1 receptor 5NX2 - -
TM7 1184 H 7.57x57 GLP-1 receptor 5NX2 - -
TM7 1185 C 7.58x58 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 1186 I 7.59x59 GLP-1 receptor 5NX2 ADGRG3 7D77
TM7 1187 L 7.60x60 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
TM7 1188 R 7.61x61 ADGRG3 7D77 - -
H8 1189 R 8.48x48 GLP-1 receptor 5NX2 - -
H8 1190 E 8.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
H8 1191 V 8.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
H8 1192 Q 8.51x51 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
H8 1193 D 8.52x52 GLP-1 receptor 5NX2 - -
H8 1194 A 8.53x53 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
H8 1195 V 8.54x54 GLP-1 receptor 5NX2 CRF2 receptor 6PB1
H8 1196 K 8.55x55 GLP-1 receptor 5NX2 CT receptor 6NIY
H8 1197 C 8.56x56 GLP-1 receptor 5NX2 - -
H8 1198 R 8.57x57 GLP-1 receptor 5NX2 CRF1 receptor 6PB0
H8 1199 V 8.58x58 CRF1 receptor 6PB0 - -
H8 1200 V 8.59x59 CRF1 receptor 6PB0 GLP-2 receptor 7D68
H8 1201 D 8.60x60 CRF1 receptor 6PB0 - -
H8 1202 R 8.61x61 CRF1 receptor 6PB0 - -
H8 1203 Q 8.62x62 CRF1 receptor 6PB0 CRF1 receptor 6PB0
H8 1204 E 8.63x63 CRF1 receptor 6PB0 - -
C-term 1205 E - - - - -
C-term 1206 G - - - - -
C-term 1207 N - - - - -
C-term 1208 G - - - - -
C-term 1209 D - - - - -