ADGRL1 homology model

PROTEIN CLASS

Class B2 (Adhesion)

RECEPTOR

SPECIES

Homo sapiens

STATE

Intermediate

VERSION

2020-09-02

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

GLP-1 receptor (sequence similarity: 32%) PDB: 5NX2

TEMPLATES

5UZ7 (CT receptor)
5NX2 (GLP-1 receptor)
6WZG (secretin receptor)
6WI9 (secretin receptor)
4Z9G (CRF1 receptor)
6M1H (PAC1 receptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 78.5 7.2 14.3
Side-chains 19.7 23.7 56.6

Number of backbone templates: 6
Number of rotamer templates: 14

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 843 V - - - -
N-term 844 L - - - -
N-term 845 M - - - -
N-term 846 A - - - -
N-term 847 H - - - -
TM1 848 R 1.27x27 CT receptor 5UZ7 - -
TM1 849 E 1.28x28 CT receptor 5UZ7 - -
TM1 850 I 1.29x29 CT receptor 5UZ7 - -
TM1 851 Y 1.30x30 CT receptor 5UZ7 - -
TM1 852 Q 1.31x31 CT receptor 5UZ7 - -
TM1 853 G 1.32x32 CT receptor 5UZ7 - -
TM1 854 R 1.33x33 GLP-1 receptor 5NX2 - -
TM1 855 I 1.34x34 GLP-1 receptor 5NX2 - -
TM1 856 N 1.35x35 GLP-1 receptor 5NX2 CT receptor 6NIY
TM1 857 E 1.36x36 GLP-1 receptor 5NX2 - -
TM1 858 L 1.37x37 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 859 L 1.38x38 GLP-1 receptor 5NX2 - -
TM1 860 L 1.39x39 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 861 S 1.40x40 GLP-1 receptor 5NX2 - -
TM1 862 V 1.41x41 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM1 863 I 1.42x42 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 864 T 1.43x43 GLP-1 receptor 5NX2 calcitonin receptor-like receptor 6UUS
TM1 865 W 1.44x44 GLP-1 receptor 5NX2 - -
TM1 866 V 1.45x45 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 867 G 1.46x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 868 I 1.47x47 GLP-1 receptor 5NX2 - -
TM1 869 V 1.48x48 GLP-1 receptor 5NX2 - -
TM1 870 I 1.49x49 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM1 871 S 1.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 872 L 1.51x51 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM1 873 V 1.52x52 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM1 874 C 1.53x53 GLP-1 receptor 5NX2 - -
TM1 875 L 1.54x54 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 876 A 1.55x55 GLP-1 receptor 5NX2 - -
TM1 877 I 1.56x56 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM1 878 C 1.57x57 GLP-1 receptor 5NX2 - -
TM1 879 I 1.58x58 GLP-1 receptor 5NX2 - -
TM1 880 S 1.59x59 GLP-1 receptor 5NX2 - -
TM1 881 T 1.60x60 GLP-1 receptor 5NX2 - -
TM1 882 F 1.61x61 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM1 883 C 1.62x62 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM1 884 F 1.63x63 GLP-1 receptor 5NX2 CT receptor 6NIY
TM1 885 L 1.64x64 GLP-1 receptor 5NX2 CRF1 receptor 6P9X
ICL1 886 R 12.48x48 - - - -
ICL1 887 G 12.49x49 secretin receptor 6WZG - -
ICL1 888 L 12.50x50 secretin receptor 6WZG secretin receptor 6WZG
ICL1 889 Q 12.51x51 - - - -
TM2 890 T 2.44x44 GLP-1 receptor 5NX2 - -
TM2 891 D 2.45x45 GLP-1 receptor 5NX2 - -
TM2 892 R 2.46x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 893 N 2.47x47 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 894 T 2.48x48 GLP-1 receptor 5NX2 CT receptor 6NIY
TM2 895 I 2.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 896 H 2.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 897 K 2.51x51 GLP-1 receptor 5NX2 CT receptor 6NIY
TM2 898 N 2.52x52 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 899 L 2.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 900 C 2.54x54 GLP-1 receptor 5NX2 - -
TM2 901 I 2.55x55 GLP-1 receptor 5NX2 - -
TM2 902 N 2.56x56 GLP-1 receptor 5NX2 - -
TM2 903 L 2.57x57 GLP-1 receptor 5NX2 - -
TM2 904 F 2.58x58 GLP-1 receptor 5NX2 - -
TM2 905 L 2.59x59 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 906 A 2.60x60 GLP-1 receptor 5NX2 - -
TM2 907 E 2.61x61 GLP-1 receptor 5NX2 - -
TM2 908 L 2.62x62 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM2 909 L 2.63x63 GLP-1 receptor 5NX2 - -
TM2 910 F 2.64x64 GLP-1 receptor 5NX2 - -
TM2 911 L 2.65x65 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM2 912 V 2.66x66 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM2 913 G 2.67x67 GLP-1 receptor 5NX2 - -
TM2 914 I 2.68x68 GLP-1 receptor 5NX2 - -
TM2 915 D 2.69x69 GLP-1 receptor 5NX2 - -
TM2 916 K 2.70x70 GLP-1 receptor 5NX2 - -
ECL1 917 T - - - -
ECL1 918 Q - - - -
ECL1 919 Y - - - -
ECL1 920 E - - - -
TM3 921 I 3.27x27 GLP-1 receptor 5NX2 - -
TM3 922 A 3.28x28 GLP-1 receptor 5NX2 GLP-1 receptor 5VEW
TM3 923 C 3.29x29 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 924 P 3.30x30 GLP-1 receptor 5NX2 - -
TM3 925 I 3.31x31 GLP-1 receptor 5NX2 CT receptor 6NIY
TM3 926 F 3.32x32 GLP-1 receptor 5NX2 - -
TM3 927 A 3.33x33 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
TM3 928 G 3.34x34 GLP-1 receptor 5NX2 - -
TM3 929 L 3.35x35 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM3 930 L 3.36x36 GLP-1 receptor 5NX2 - -
TM3 931 H 3.37x37 GLP-1 receptor 5NX2 PAC1 receptor 6P9Y
TM3 932 Y 3.38x38 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 933 F 3.39x39 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM3 934 F 3.40x40 GLP-1 receptor 5NX2 - -
TM3 935 L 3.41x41 GLP-1 receptor 5NX2 - -
TM3 936 A 3.42x42 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 937 A 3.43x43 GLP-1 receptor 5NX2 - -
TM3 938 F 3.44x44 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM3 939 S 3.45x45 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM3 940 W 3.46x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 941 L 3.47x47 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 942 C 3.48x48 GLP-1 receptor 5NX2 - -
TM3 943 L 3.49x49 GLP-1 receptor 5NX2 - -
TM3 944 E 3.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 945 G 3.51x51 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 946 V 3.52x52 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 947 H 3.53x53 GLP-1 receptor 5NX2 - -
TM3 948 L 3.54x54 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 949 Y 3.55x55 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 950 L 3.56x56 GLP-1 receptor 5NX2 - -
TM3 951 L 3.57x57 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 952 L 3.58x58 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM3 953 V 3.59x59 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM3 954 E 3.60x60 GLP-1 receptor 5NX2 - -
ICL2 955 V - - - -
ICL2 956 F secretin receptor 6WI9 secretin receptor 6WI9
ICL2 957 E secretin receptor 6WI9 - -
ICL2 958 S secretin receptor 6WI9 secretin receptor 6WI9
ICL2 959 E secretin receptor 6WI9 secretin receptor 6WI9
ICL2 960 Y - - - -
TM4 961 S 4.40x41 GLP-1 receptor 5NX2 glucagon receptor 5EE7
TM4 962 R 4.41x42 GLP-1 receptor 5NX2 CT receptor 6NIY
TM4 963 T 4.42x43 GLP-1 receptor 5NX2 - -
TM4 964 K 4.43x44 GLP-1 receptor 5NX2 GLP-1 receptor 5VAI
TM4 965 Y 4.44x45 GLP-1 receptor 5NX2 - -
TM4 966 Y 4.45x46 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 967 Y 4.46x47 GLP-1 receptor 5NX2 CT receptor 6NIY
TM4 968 L 4.47x48 GLP-1 receptor 5NX2 CT receptor 6NIY
TM4 969 G 4.48x49 GLP-1 receptor 5NX2 - -
TM4 970 G 4.49x491 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 971 Y 4.50x50 GLP-1 receptor 5NX2 - -
TM4 972 C 4.51x51 GLP-1 receptor 5NX2 CRF2 receptor 6PB1
TM4 973 F 4.52x52 GLP-1 receptor 5NX2 CT receptor 6NIY
TM4 974 P 4.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 975 A 4.54x54 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM4 976 L 4.55x55 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 977 V 4.56x56 GLP-1 receptor 5NX2 - -
TM4 978 V 4.57x57 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 979 G 4.58x58 GLP-1 receptor 5NX2 - -
TM4 980 I 4.59x59 GLP-1 receptor 5NX2 CT receptor 6NIY
TM4 981 A 4.60x60 GLP-1 receptor 5NX2 - -
TM4 982 A 4.61x61 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM4 983 A 4.62x62 GLP-1 receptor 5NX2 - -
TM4 984 I 4.63x63 GLP-1 receptor 5NX2 - -
TM4 985 D 4.64x64 GLP-1 receptor 5NX2 - -
TM4 986 Y 4.65x65 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM4 987 R 4.66x66 GLP-1 receptor 5NX2 - -
TM4 988 S 4.67x67 GLP-1 receptor 5NX2 - -
TM4 989 Y 4.68x68 CRF1 receptor 4Z9G calcitonin receptor-like receptor 6UUS
ECL2 990 G - - - -
ECL2 991 T - - - -
ECL2 992 E - - - -
ECL2 993 K - - - -
ECL2 994 A - - - -
ECL2 995 C 45.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ECL2 996 W 45.51x51 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
ECL2 997 L 45.52x52 GLP-1 receptor 5NX2 CT receptor 6NIY
ECL2 998 R - - - -
ECL2 999 V - - - -
TM5 1000 D 5.32x32 - - - -
TM5 1001 N 5.33x33 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1002 Y 5.34x34 GLP-1 receptor 5NX2 - -
TM5 1003 F 5.35x35 GLP-1 receptor 5NX2 - -
TM5 1004 I 5.36x36 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM5 1005 W 5.37x37 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1006 S 5.38x38 GLP-1 receptor 5NX2 - -
TM5 1007 F 5.39x39 GLP-1 receptor 5NX2 - -
TM5 1008 I 5.40x40 GLP-1 receptor 5NX2 - -
TM5 1009 G 5.41x41 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM5 1010 P 5.42x42 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1011 V 5.43x43 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM5 1012 S 5.44x44 GLP-1 receptor 5NX2 - -
TM5 1013 F 5.45x45 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1014 V 5.46x46 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM5 1015 I 5.47x47 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1016 V 5.48x48 GLP-1 receptor 5NX2 CT receptor 6NIY
TM5 1017 V 5.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1018 N 5.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM5 1019 L 5.51x51 GLP-1 receptor 5NX2 calcitonin receptor-like receptor 6UUS
TM5 1020 V 5.52x52 GLP-1 receptor 5NX2 CRF2 receptor 6PB1
TM5 1021 F 5.53x53 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM5 1022 L 5.54x54 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM5 1023 M 5.55x55 GLP-1 receptor 5NX2 - -
TM5 1024 V 5.56x56 GLP-1 receptor 5NX2 - -
TM5 1025 T 5.57x57 GLP-1 receptor 5NX2 - -
TM5 1026 L 5.58x58 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM5 1027 H 5.59x59 GLP-1 receptor 5NX2 - -
TM5 1028 K 5.60x60 GLP-1 receptor 5NX2 - -
TM5 1029 M 5.61x61 GLP-1 receptor 5NX2 - -
TM5 1030 I 5.62x62 GLP-1 receptor 5NX2 calcitonin receptor-like receptor 6UUS
TM5 1031 R 5.63x63 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM5 1032 S 5.64x64 GLP-1 receptor 5NX2 - -
TM5 1033 S 5.65x65 GLP-1 receptor 5NX2 - -
ICL3 1034 S - - - -
ICL3 1035 V - - - -
ICL3 1036 L - - - -
ICL3 1037 K - - - -
ICL3 1038 P - - - -
ICL3 1040 S - - - -
ICL3 1041 S - - - -
ICL3 1042 R - - - -
ICL3 1043 L - - - -
ICL3 1044 D - - - -
TM6 1045 N 6.34x34 GLP-1 receptor 5NX2 - -
TM6 1046 I 6.35x35 GLP-1 receptor 5NX2 - -
TM6 1047 K 6.36x36 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM6 1048 S 6.37x37 GLP-1 receptor 5NX2 - -
TM6 1049 W 6.38x38 GLP-1 receptor 5NX2 - -
TM6 1050 A 6.39x39 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 1051 L 6.40x40 GLP-1 receptor 5NX2 - -
TM6 1052 G 6.41x41 GLP-1 receptor 5NX2 - -
TM6 1053 A 6.42x42 GLP-1 receptor 5NX2 - -
TM6 1054 I 6.43x43 GLP-1 receptor 5NX2 - -
TM6 1055 A 6.44x44 GLP-1 receptor 5NX2 - -
TM6 1056 L 6.45x45 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 1057 L 6.46x46 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM6 1058 F 6.47x47 GLP-1 receptor 5NX2 - -
TM6 1059 L 6.48x48 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 1060 L 6.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM6 1061 G 6.50x50 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM6 1062 L 6.51x51 GLP-1 receptor 5NX2 - -
TM6 1063 T 6.52x52 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM6 1064 W 6.53x53 GLP-1 receptor 5NX2 - -
TM6 1065 A 6.54x54 GLP-1 receptor 5NX2 - -
TM6 1066 F 6.55x55 GLP-1 receptor 5NX2 - -
TM6 1067 G 6.56x56 GLP-1 receptor 5NX2 - -
TM6 1068 L 6.57x57 GLP-1 receptor 5NX2 - -
TM6 1069 L 6.58x58 GLP-1 receptor 5NX2 PTH1 receptor 6FJ3
TM6 1070 F 6.59x59 PAC1 receptor 6M1H - -
ECL3 1071 I - - - -
ECL3 1072 N - - - -
ECL3 1073 K - - - -
ECL3 1074 E - - - -
TM7 1075 S 7.35x34 GLP-1 receptor 5NX2 - -
TM7 1076 V 7.36x35 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM7 1077 V 7.37x36 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM7 1078 M 7.38x37 GLP-1 receptor 5NX2 - -
TM7 1079 A 7.39x38 GLP-1 receptor 5NX2 - -
TM7 1080 Y 7.40x39 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM7 1081 L 7.41x40 GLP-1 receptor 5NX2 - -
TM7 1082 F 7.42x41 GLP-1 receptor 5NX2 - -
TM7 1083 T 7.43x42 GLP-1 receptor 5NX2 - -
TM7 1084 T 7.44x43 GLP-1 receptor 5NX2 - -
TM7 1085 F 7.45x44 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 1086 N 7.46x45 GLP-1 receptor 5NX2 PTH1 receptor 6FJ3
TM7 1087 A 7.47x46 GLP-1 receptor 5NX2 - -
TM7 1088 F 7.48x47 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 1089 Q 7.49x49 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 1090 G 7.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 1091 V 7.51x51 GLP-1 receptor 5NX2 - -
TM7 1092 F 7.52x52 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM7 1093 I 7.53x53 GLP-1 receptor 5NX2 - -
TM7 1094 F 7.54x54 GLP-1 receptor 5NX2 - -
TM7 1095 V 7.55x55 GLP-1 receptor 5NX2 secretin receptor 6WZG
TM7 1096 F 7.56x56 GLP-1 receptor 5NX2 CRF1 receptor 4Z9G
TM7 1097 H 7.57x57 GLP-1 receptor 5NX2 - -
TM7 1098 C 7.58x58 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
TM7 1099 A 7.59x59 GLP-1 receptor 5NX2 - -
TM7 1100 L 7.60x60 GLP-1 receptor 5NX2 secretin receptor 6WZG
H8 1101 Q 8.47x47 GLP-1 receptor 5NX2 - -
H8 1102 K 8.48x48 GLP-1 receptor 5NX2 glucagon receptor 5XEZ
H8 1103 K 8.49x49 GLP-1 receptor 5NX2 - -
H8 1104 V 8.50x50 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
H8 1105 H 8.51x51 GLP-1 receptor 5NX2 - -
H8 1106 K 8.52x52 GLP-1 receptor 5NX2 - -
H8 1107 E 8.53x53 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
H8 1108 Y 8.54x54 GLP-1 receptor 5NX2 - -
H8 1109 S 8.55x55 GLP-1 receptor 5NX2 - -
H8 1110 K 8.56x56 GLP-1 receptor 5NX2 GLP-1 receptor 5NX2
H8 1111 C 8.57x57 GLP-1 receptor 5NX2 - -
H8 1112 L 8.58x58 secretin receptor 6WZG - -
H8 1113 R 8.59x59 secretin receptor 6WZG PAC1 receptor 6P9Y
H8 1114 H 8.60x60 secretin receptor 6WZG - -
H8 1115 S 8.61x61 secretin receptor 6WZG - -
H8 1116 Y 8.62x62 secretin receptor 6WZG - -
H8 1117 C 8.63x63 secretin receptor 6WZG - -
C-term 1118 C - - - -
C-term 1119 I - - - -
C-term 1120 R - - - -
C-term 1121 S - - - -
C-term 1122 P - - - -