GnRH1 receptor homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Intermediate
VERSION
2021-10-06
MODEL
TEMPLATES
3VW7 (PAR1)
5WQC (OX2 receptor)
7BR3 (GnRH1 receptor)
7EZM (CCK1 receptor)
4UHR (A2A receptor)
7E2X (5-HT1A receptor)
None
5WQC (OX2 receptor)
7BR3 (GnRH1 receptor)
7EZM (CCK1 receptor)
4UHR (A2A receptor)
7E2X (5-HT1A receptor)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 72.2 | 16.2 | 11.6 |
| Side-chains | 17.5 | 63.9 | 18.5 |
Number of backbone templates: 6
Number of rotamer templates: 32
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 27 | N | - | PAR1 | 3VW7 | PAR1 | 3VW7 |
| N-term | 28 | L | - | PAR1 | 3VW7 | PAR1 | 3VW7 |
| N-term | 29 | P | - | PAR1 | 3VW7 | PAR1 | 3VW7 |
| N-term | 30 | T | - | PAR1 | 3VW7 | PAR1 | 3VW7 |
| N-term | 31 | L | - | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM1 | 32 | T | 1.29x29 | PAR1 | 3VW7 | M2 receptor | 5YC8 |
| TM1 | 33 | L | 1.30x30 | PAR1 | 3VW7 | PAR2 | 5NDD |
| TM1 | 34 | S | 1.31x31 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 35 | G | 1.32x32 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 36 | K | 1.33x33 | PAR1 | 3VW7 | S1P1 receptor | 3V2Y |
| TM1 | 37 | I | 1.34x34 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 38 | R | 1.35x35 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 39 | V | 1.36x36 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 40 | T | 1.37x37 | PAR1 | 3VW7 | CysLT1 receptor | 6RZ4 |
| TM1 | 41 | V | 1.38x38 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM1 | 42 | T | 1.39x39 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 43 | F | 1.40x40 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 44 | F | 1.41x41 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 45 | L | 1.42x42 | PAR1 | 3VW7 | P2Y12 receptor | 4NTJ |
| TM1 | 46 | F | 1.43x43 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM1 | 47 | L | 1.44x44 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 48 | L | 1.45x45 | PAR1 | 3VW7 | PAF receptor | 5ZKQ |
| TM1 | 49 | S | 1.46x46 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM1 | 50 | A | 1.47x47 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 51 | T | 1.48x48 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 52 | F | 1.49x49 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 53 | N | 1.50x50 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM1 | 54 | A | 1.51x51 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 55 | S | 1.52x52 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 56 | F | 1.53x53 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 57 | L | 1.54x54 | PAR1 | 3VW7 | CysLT1 receptor | 6RZ4 |
| TM1 | 58 | L | 1.55x55 | PAR1 | 3VW7 | 5-HT2B receptor | 5TVN |
| TM1 | 59 | K | 1.56x56 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 60 | L | 1.57x57 | PAR1 | 3VW7 | CysLT1 receptor | 6RZ4 |
| TM1 | 61 | Q | 1.58x58 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM1 | 62 | K | 1.59x59 | PAR1 | 3VW7 | OX2 receptor | 5WQC |
| TM1 | 63 | W | 1.60x60 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| ICL1 | 64 | T | - | - | - | - | - |
| ICL1 | 65 | Q | - | - | - | - | - |
| ICL1 | 66 | K | - | - | - | - | - |
| ICL1 | 67 | K | - | - | - | - | - |
| ICL1 | 68 | E | - | - | - | - | - |
| ICL1 | 69 | K | - | - | - | - | - |
| ICL1 | 70 | G | - | - | - | - | - |
| ICL1 | 71 | K | 12.48x48 | OX2 receptor | 5WQC | 5-HT2B receptor | 4IB4 |
| ICL1 | 72 | K | 12.49x49 | OX2 receptor | 5WQC | 5-HT2B receptor | 4NC3 |
| ICL1 | 73 | L | 12.50x50 | OX2 receptor | 5WQC | 5-HT2B receptor | 5TVN |
| ICL1 | 74 | S | 12.51x51 | - | - | - | - |
| TM2 | 75 | R | 2.38x38 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM2 | 76 | M | 2.39x39 | PAR1 | 3VW7 | MC4 receptor | 6W25 |
| TM2 | 77 | K | 2.40x40 | PAR1 | 3VW7 | PAF receptor | 5ZKQ |
| TM2 | 78 | L | 2.41x41 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM2 | 79 | L | 2.42x42 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM2 | 80 | L | 2.43x43 | PAR1 | 3VW7 | 5-HT2B receptor | 5TVN |
| TM2 | 81 | K | 2.44x44 | PAR1 | 3VW7 | P2Y12 receptor | 4NTJ |
| TM2 | 82 | H | 2.45x45 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM2 | 83 | L | 2.46x46 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM2 | 84 | T | 2.47x47 | PAR1 | 3VW7 | PAF receptor | 5ZKQ |
| TM2 | 85 | L | 2.48x48 | PAR1 | 3VW7 | PAR2 | 5NDD |
| TM2 | 86 | A | 2.49x49 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM2 | 87 | N | 2.50x50 | PAR1 | 3VW7 | CysLT2 receptor | 6RZ6 |
| TM2 | 88 | L | 2.51x51 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM2 | 89 | L | 2.52x52 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM2 | 90 | E | 2.53x53 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM2 | 91 | T | 2.54x54 | PAR1 | 3VW7 | FFA1 receptor | 5TZY |
| TM2 | 92 | L | 2.55x55 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| TM2 | 93 | I | 2.56x551 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| TM2 | 94 | V | 2.57x56 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| TM2 | 95 | M | 2.58x57 | PAR1 | 3VW7 | 5-HT2B receptor | 5TVN |
| TM2 | 96 | P | 2.59x58 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM2 | 97 | L | 2.60x59 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM2 | 98 | D | 2.61x60 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM2 | 99 | G | 2.62x61 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM2 | 100 | M | 2.63x62 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM2 | 101 | W | 2.64x63 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM2 | 102 | N | 2.65x64 | PAR1 | 3VW7 | CCK1 receptor | 7EZM |
| ECL1 | 103 | I | - | - | - | - | - |
| ECL1 | 104 | T | - | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| ECL1 | 105 | V | - | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| ECL1 | 106 | Q | 23.49x49 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| ECL1 | 107 | W | 23.50x50 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| ECL1 | 108 | Y | 23.51x51 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| ECL1 | 109 | A | 23.52x52 | - | - | - | - |
| TM3 | 110 | G | 3.21x21 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 111 | E | 3.22x22 | PAR1 | 3VW7 | PAR2 | 5NDD |
| TM3 | 112 | L | 3.23x23 | PAR1 | 3VW7 | CysLT2 receptor | 6RZ6 |
| TM3 | 113 | L | 3.24x24 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 114 | C | 3.25x25 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 115 | K | 3.26x26 | PAR1 | 3VW7 | P2Y1 receptor | 4XNW |
| TM3 | 116 | V | 3.27x27 | PAR1 | 3VW7 | PAF receptor | 5ZKQ |
| TM3 | 117 | L | 3.28x28 | PAR1 | 3VW7 | PAR2 | 5NDD |
| TM3 | 118 | S | 3.29x29 | PAR1 | 3VW7 | CysLT2 receptor | 6RZ6 |
| TM3 | 119 | Y | 3.30x30 | PAR1 | 3VW7 | CysLT2 receptor | 6RZ6 |
| TM3 | 120 | L | 3.31x31 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM3 | 121 | K | 3.32x32 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM3 | 122 | L | 3.33x33 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM3 | 123 | F | 3.34x34 | PAR1 | 3VW7 | P2Y12 receptor | 4NTJ |
| TM3 | 124 | S | 3.35x35 | PAR1 | 3VW7 | MC4 receptor | 6W25 |
| TM3 | 125 | M | 3.36x36 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 126 | Y | 3.37x37 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 127 | A | 3.38x38 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 128 | P | 3.39x39 | PAR1 | 3VW7 | TP receptor | 6IIV |
| TM3 | 129 | A | 3.40x40 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM3 | 130 | F | 3.41x41 | PAR1 | 3VW7 | CysLT1 receptor | 6RZ4 |
| TM3 | 131 | M | 3.42x42 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM3 | 132 | M | 3.43x43 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 133 | V | 3.44x44 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM3 | 134 | V | 3.45x45 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 135 | I | 3.46x46 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 136 | S | 3.47x47 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 137 | L | 3.48x48 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM3 | 138 | D | 3.49x49 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 139 | R | 3.50x50 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 140 | S | 3.51x51 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM3 | 141 | L | 3.52x52 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 142 | A | 3.53x53 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM3 | 143 | I | 3.54x54 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM3 | 144 | T | 3.55x55 | PAR1 | 3VW7 | PAF receptor | 5ZKQ |
| TM3 | 145 | R | 3.56x56 | PAR1 | 3VW7 | PAF receptor | 5ZKQ |
| ICL2 | 146 | P | 34.50x50 | - | - | - | - |
| ICL2 | 147 | L | 34.51x51 | CCK1 receptor | 7EZM | CCK1 receptor | 7EZM |
| ICL2 | 148 | A | 34.52x52 | CCK1 receptor | 7EZM | MT2 receptor | 6ME7 |
| ICL2 | 149 | L | 34.53x53 | CCK1 receptor | 7EZM | - | - |
| ICL2 | 150 | K | - | CCK1 receptor | 7EZM | - | - |
| ICL2 | 151 | S | - | CCK1 receptor | 7EZM | - | - |
| TM4 | 152 | N | 4.38x38 | PAR1 | 3VW7 | Y1 receptor | 5ZBH |
| TM4 | 153 | S | 4.39x39 | PAR1 | 3VW7 | NOP receptor | 5DHH |
| TM4 | 154 | K | 4.40x40 | PAR1 | 3VW7 | P2Y1 receptor | 4XNW |
| TM4 | 155 | V | 4.41x41 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM4 | 156 | G | 4.42x42 | PAR1 | 3VW7 | PAF receptor | 5ZKQ |
| TM4 | 157 | Q | 4.43x43 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM4 | 158 | S | 4.44x44 | PAR1 | 3VW7 | PAF receptor | 5ZKQ |
| TM4 | 159 | M | 4.45x45 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM4 | 160 | V | 4.46x46 | PAR1 | 3VW7 | TP receptor | 6IIV |
| TM4 | 161 | G | 4.47x47 | PAR1 | 3VW7 | CysLT2 receptor | 6RZ6 |
| TM4 | 162 | L | 4.48x48 | PAR1 | 3VW7 | P2Y1 receptor | 4XNW |
| TM4 | 163 | A | 4.49x49 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM4 | 164 | W | 4.50x50 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM4 | 165 | I | 4.51x51 | PAR1 | 3VW7 | CysLT2 receptor | 6RZ6 |
| TM4 | 166 | L | 4.52x52 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM4 | 167 | S | 4.53x53 | PAR1 | 3VW7 | 5-HT2B receptor | 5TVN |
| TM4 | 168 | S | 4.54x54 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM4 | 169 | V | 4.55x55 | PAR1 | 3VW7 | P2Y1 receptor | 4XNW |
| TM4 | 170 | F | 4.56x56 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM4 | 171 | A | 4.57x57 | PAR1 | 3VW7 | 5-HT2B receptor | 5TVN |
| TM4 | 172 | G | 4.58x59 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM4 | 173 | P | 4.59x60 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM4 | 174 | Q | 4.60x61 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM4 | 175 | L | 4.61x62 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM4 | 176 | Y | 4.62x63 | PAR1 | 3VW7 | P2Y1 receptor | 4XNW |
| TM4 | 177 | I | 4.63x64 | PAR1 | 3VW7 | - | - |
| TM4 | 178 | F | 4.64x65 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| ECL2 | 179 | R | - | - | - | - | - |
| ECL2 | 180 | M | - | - | - | - | - |
| ECL2 | 181 | I | - | - | - | - | - |
| ECL2 | 182 | H | - | - | - | - | - |
| ECL2 | 183 | L | - | - | - | - | - |
| ECL2 | 184 | A | - | - | - | - | - |
| ECL2 | 185 | D | - | - | - | - | - |
| ECL2 | 186 | S | - | - | - | - | - |
| ECL2 | 187 | S | - | - | - | - | - |
| ECL2 | 188 | G | - | - | - | - | - |
| ECL2 | 189 | Q | - | - | - | - | - |
| ECL2 | 190 | T | - | - | - | - | - |
| ECL2 | 191 | K | - | - | - | - | - |
| ECL2 | 192 | V | - | - | - | - | - |
| ECL2 | 193 | F | - | - | - | - | - |
| ECL2 | 194 | S | - | - | - | - | - |
| ECL2 | 195 | Q | - | - | - | - | - |
| ECL2 | 196 | C | 45.50x50 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| ECL2 | 197 | V | 45.51x51 | PAR1 | 3VW7 | - | - |
| ECL2 | 198 | T | 45.52x52 | PAR1 | 3VW7 | US28 | 4XT1 |
| ECL2 | 199 | H | - | - | - | - | - |
| ECL2 | 200 | C | - | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| ECL2 | 201 | S | - | GnRH1 receptor | 7BR3 | - | - |
| ECL2 | 202 | F | - | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| ECL2 | 203 | S | - | - | - | - | - |
| TM5 | 204 | Q | 5.31x32 | PAR1 | 3VW7 | - | - |
| TM5 | 205 | W | 5.32x33 | PAR1 | 3VW7 | - | - |
| TM5 | 206 | W | 5.33x34 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM5 | 207 | H | 5.34x35 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM5 | 208 | Q | 5.35x36 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM5 | 209 | A | 5.36x37 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM5 | 210 | F | 5.37x38 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM5 | 211 | Y | 5.38x39 | PAR1 | 3VW7 | PAR2 | 5NDD |
| TM5 | 212 | N | 5.39x40 | PAR1 | 3VW7 | CysLT2 receptor | 6RZ6 |
| TM5 | 213 | F | 5.40x41 | PAR1 | 3VW7 | FFA1 receptor | 5TZY |
| TM5 | 214 | F | 5.41x42 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM5 | 215 | T | 5.42x43 | PAR1 | 3VW7 | P2Y1 receptor | 4XNW |
| TM5 | 216 | F | 5.43x44 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM5 | 217 | S | 5.44x45 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM5 | 218 | C | 5.45x46 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| TM5 | 219 | L | 5.46x461 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| TM5 | 220 | F | 5.47x47 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| TM5 | 221 | I | 5.48x48 | PAR1 | 3VW7 | CysLT1 receptor | 6RZ4 |
| TM5 | 222 | I | 5.49x49 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM5 | 223 | P | 5.50x50 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM5 | 224 | L | 5.51x51 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM5 | 225 | F | 5.52x52 | PAR1 | 3VW7 | CysLT2 receptor | 6RZ6 |
| TM5 | 226 | I | 5.53x53 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM5 | 227 | M | 5.54x54 | PAR1 | 3VW7 | 5-HT2B receptor | 5TVN |
| TM5 | 228 | L | 5.55x55 | PAR1 | 3VW7 | PAF receptor | 5ZKQ |
| TM5 | 229 | I | 5.56x56 | PAR1 | 3VW7 | CysLT2 receptor | 6RZ6 |
| TM5 | 230 | C | 5.57x57 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM5 | 231 | N | 5.58x58 | PAR1 | 3VW7 | PAF receptor | 5ZKQ |
| TM5 | 232 | A | 5.59x59 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM5 | 233 | K | 5.60x60 | PAR1 | 3VW7 | succinate receptor | 6RNK |
| TM5 | 234 | I | 5.61x61 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM5 | 235 | I | 5.62x62 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM5 | 236 | F | 5.63x63 | PAR1 | 3VW7 | GPR52 | 6LI1 |
| TM5 | 237 | T | 5.64x64 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM5 | 238 | L | 5.65x65 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM5 | 239 | T | 5.66x66 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM5 | 240 | R | 5.67x67 | PAR1 | 3VW7 | CCR5 | 7F1T |
| TM5 | 241 | V | 5.68x68 | CCK1 receptor | 7EZM | CysLT2 receptor | 6RZ6 |
| TM5 | 242 | L | 5.69x69 | CCK1 receptor | 7EZM | GnRH1 receptor | 7BR3 |
| TM5 | 243 | H | 5.70x70 | CCK1 receptor | 7EZM | 5-HT1F receptor | 7EXD |
| TM5 | 244 | Q | 5.71x71 | CCK1 receptor | 7EZM | NTS1 receptor | 6OSA |
| TM5 | 245 | D | 5.72x72 | CCK1 receptor | 7EZM | - | - |
| TM5 | 246 | P | 5.73x73 | CCK1 receptor | 7EZM | - | - |
| TM5 | 247 | H | 5.74x74 | CCK1 receptor | 7EZM | - | - |
| ICL3 | 248 | E | - | - | - | - | - |
| ICL3 | 249 | L | - | A2A receptor | 4UHR | - | - |
| ICL3 | 250 | Q | - | A2A receptor | 4UHR | - | - |
| ICL3 | 251 | L | - | A2A receptor | 4UHR | - | - |
| ICL3 | 252 | N | - | - | - | - | - |
| TM6 | 253 | Q | 6.21x21 | 5-HT1A receptor | 7E2X | - | - |
| TM6 | 254 | S | 6.22x22 | 5-HT1A receptor | 7E2X | - | - |
| TM6 | 255 | K | 6.23x23 | 5-HT1A receptor | 7E2X | 5-HT1D receptor | 7E32 |
| TM6 | 256 | N | 6.24x24 | 5-HT1A receptor | 7E2X | Rhodopsin | 6I9K |
| TM6 | 257 | N | 6.25x25 | 5-HT1A receptor | 7E2X | - | - |
| TM6 | 258 | I | 6.26x26 | 5-HT1A receptor | 7E2X | D4 receptor | 6IQL |
| TM6 | 259 | P | 6.27x27 | PAR1 | 3VW7 | M2 receptor | 4MQT |
| TM6 | 260 | R | 6.28x28 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM6 | 261 | A | 6.29x29 | PAR1 | 3VW7 | MC4 receptor | 6W25 |
| TM6 | 262 | R | 6.30x30 | PAR1 | 3VW7 | FFA1 receptor | 5TZY |
| TM6 | 263 | L | 6.31x31 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM6 | 264 | K | 6.32x32 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM6 | 265 | T | 6.33x33 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM6 | 266 | L | 6.34x34 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM6 | 267 | K | 6.35x35 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM6 | 268 | M | 6.36x36 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM6 | 269 | T | 6.37x37 | PAR1 | 3VW7 | CysLT2 receptor | 6RZ6 |
| TM6 | 270 | V | 6.38x38 | PAR1 | 3VW7 | succinate receptor | 6RNK |
| TM6 | 271 | A | 6.39x39 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM6 | 272 | F | 6.40x40 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM6 | 273 | A | 6.41x41 | PAR1 | 3VW7 | FFA1 receptor | 5TZY |
| TM6 | 274 | T | 6.42x42 | PAR1 | 3VW7 | CysLT1 receptor | 6RZ4 |
| TM6 | 275 | S | 6.43x43 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM6 | 276 | F | 6.44x44 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM6 | 277 | T | 6.45x45 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM6 | 278 | V | 6.46x46 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| TM6 | 279 | C | 6.47x47 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| TM6 | 280 | W | 6.48x48 | PAR1 | 3VW7 | 5-HT2B receptor | 5TVN |
| TM6 | 281 | T | 6.49x49 | PAR1 | 3VW7 | PAR2 | 5NDD |
| TM6 | 282 | P | 6.50x50 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM6 | 283 | Y | 6.51x51 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM6 | 284 | Y | 6.52x52 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM6 | 285 | V | 6.53x53 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM6 | 286 | L | 6.54x54 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM6 | 287 | G | 6.55x55 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM6 | 288 | I | 6.56x56 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM6 | 289 | W | 6.57x57 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM6 | 290 | Y | 6.58x58 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM6 | 291 | W | 6.59x59 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM6 | 292 | F | 6.60x60 | PAR1 | 3VW7 | PAR2 | 5NDD |
| TM6 | 293 | D | 6.61x61 | PAR1 | 3VW7 | CCK1 receptor | 7EZM |
| ECL3 | 294 | P | - | - | - | - | - |
| ECL3 | 295 | E | - | GnRH1 receptor | 7BR3 | - | - |
| ECL3 | 296 | M | - | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| ECL3 | 297 | L | - | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| ECL3 | 298 | N | - | GnRH1 receptor | 7BR3 | - | - |
| ECL3 | 299 | R | - | GnRH1 receptor | 7BR3 | - | - |
| ECL3 | 300 | L | - | - | - | - | - |
| TM7 | 301 | S | 7.31x30 | PAR1 | 3VW7 | - | - |
| TM7 | 302 | D | 7.32x31 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM7 | 303 | P | 7.33x32 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM7 | 304 | V | 7.34x33 | PAR1 | 3VW7 | P2Y12 receptor | 4NTJ |
| TM7 | 305 | N | 7.35x34 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM7 | 306 | H | 7.36x35 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM7 | 307 | F | 7.37x36 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM7 | 308 | F | 7.38x37 | PAR1 | 3VW7 | 5-HT2B receptor | 5TVN |
| TM7 | 309 | F | 7.39x38 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM7 | 310 | L | 7.40x39 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM7 | 311 | F | 7.41x40 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM7 | 312 | A | 7.42x41 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM7 | 313 | F | 7.43x42 | PAR1 | 3VW7 | succinate receptor | 6RNK |
| TM7 | 314 | L | 7.44x43 | PAR1 | 3VW7 | PAR2 | 5NDD |
| TM7 | 315 | N | 7.45x45 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM7 | 316 | P | 7.46x46 | PAR1 | 3VW7 | GnRH1 receptor | 7BR3 |
| TM7 | 317 | C | 7.47x47 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM7 | 318 | F | 7.48x48 | PAR1 | 3VW7 | LPA6 receptor | 5XSZ |
| TM7 | 319 | D | 7.49x49 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM7 | 320 | P | 7.50x50 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM7 | 321 | L | 7.51x51 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM7 | 322 | I | 7.52x52 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM7 | 323 | Y | 7.53x53 | PAR1 | 3VW7 | PAR1 | 3VW7 |
| TM7 | 324 | G | 7.54x54 | PAR1 | 3VW7 | FFA1 receptor | 5TZY |
| TM7 | 325 | Y | 7.55x55 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| TM7 | 326 | F | 7.56x56 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| TM7 | 327 | S | 7.57x57 | GnRH1 receptor | 7BR3 | GnRH1 receptor | 7BR3 |
| C-term | 328 | L | - | - | - | - | - |