GPR78 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

GPR78

SPECIES

Homo sapiens

STATE

Intermediate

VERSION

2021-09-08

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

MC4 receptor (sequence similarity: 25%) PDB: 6W25
Align

TEMPLATES

7EXD (5-HT1F receptor)
6W25 (MC4 receptor)
7JVR (D2 receptor)
6VMS (D2 receptor)
6M9T (EP3 receptor)
6WH4 (5-HT2A receptor)
7JVQ (D1 receptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 69.9 18.0 12.1
Side-chains 11.1 65.4 23.5

Number of backbone templates: 7
Number of rotamer templates: 65

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 1 M - - - - -
TM1 2 G 1.29x29 5-HT1F receptor 7EXD CB2 receptor 5ZTY
TM1 3 P 1.30x30 5-HT1F receptor 7EXD 5-HT1F receptor 7EXD
TM1 4 G 1.31x31 5-HT1F receptor 7EXD A2A receptor 5IU4
TM1 5 E 1.32x32 5-HT1F receptor 7EXD OX2 receptor 5WQC
TM1 6 A 1.33x33 5-HT1F receptor 7EXD D4 receptor 6IQL
TM1 7 L 1.34x34 5-HT1F receptor 7EXD 5-HT1F receptor 7EXD
TM1 8 L 1.35x35 MC4 receptor 6W25 - -
TM1 9 A 1.36x36 MC4 receptor 6W25 D2 receptor 7JVR
TM1 10 G 1.37x37 MC4 receptor 6W25 A1 receptor 5UEN
TM1 11 L 1.38x38 MC4 receptor 6W25 D2 receptor 7JVR
TM1 12 L 1.39x39 MC4 receptor 6W25 D2 receptor 7JVR
TM1 13 V 1.40x40 MC4 receptor 6W25 MC4 receptor 6W25
TM1 14 M 1.41x41 MC4 receptor 6W25 CysLT1 receptor 6RZ4
TM1 15 V 1.42x42 MC4 receptor 6W25 M5 receptor 6OL9
TM1 16 L 1.43x43 MC4 receptor 6W25 EP3 receptor 6AK3
TM1 17 A 1.44x44 MC4 receptor 6W25 D2 receptor 7JVR
TM1 18 V 1.45x45 MC4 receptor 6W25 D2 receptor 7JVR
TM1 19 A 1.46x46 MC4 receptor 6W25 5-HT1A receptor 7E2X
TM1 20 L 1.47x47 MC4 receptor 6W25 MC4 receptor 6W25
TM1 21 L 1.48x48 MC4 receptor 6W25 MC4 receptor 6W25
TM1 22 S 1.49x49 MC4 receptor 6W25 5-HT1B receptor 4IAQ
TM1 23 N 1.50x50 MC4 receptor 6W25 MC4 receptor 6W25
TM1 24 A 1.51x51 MC4 receptor 6W25 5-HT1B receptor 4IAQ
TM1 25 L 1.52x52 MC4 receptor 6W25 MC4 receptor 6W25
TM1 26 V 1.53x53 MC4 receptor 6W25 MC4 receptor 6W25
TM1 27 L 1.54x54 MC4 receptor 6W25 5-HT1D receptor 7E32
TM1 28 L 1.55x55 MC4 receptor 6W25 α2B-adrenoceptor 6K42
TM1 29 C 1.56x56 MC4 receptor 6W25 - -
TM1 30 C 1.57x57 MC4 receptor 6W25 - -
TM1 31 A 1.58x58 MC4 receptor 6W25 MC4 receptor 6W25
TM1 32 Y 1.59x59 MC4 receptor 6W25 CXCR2 6LFL
TM1 33 S 1.60x60 MC4 receptor 6W25 α2C-adrenoceptor 6KUW
ICL1 34 A 12.48x48 - - - -
ICL1 35 E 12.49x49 D2 receptor 7JVR M1 receptor 6WJC
ICL1 36 L 12.50x50 D2 receptor 7JVR D2 receptor 7JVR
ICL1 37 R 12.51x51 - - - -
TM2 38 T 2.36x36 EP3 receptor 6M9T - -
TM2 39 R 2.37x37 MC4 receptor 6W25 apelin receptor 5VBL
TM2 40 A 2.38x38 MC4 receptor 6W25 5-HT2C receptor 6BQH
TM2 41 S 2.39x39 MC4 receptor 6W25 CB1 receptor 5TGZ
TM2 42 G 2.40x40 MC4 receptor 6W25 GPBA receptor 7CFN
TM2 43 V 2.41x41 MC4 receptor 6W25 β3-adrenoceptor 7DH5
TM2 44 L 2.42x42 MC4 receptor 6W25 D2 receptor 7JVR
TM2 45 L 2.43x43 MC4 receptor 6W25 M5 receptor 6OL9
TM2 46 V 2.44x44 MC4 receptor 6W25 D2 receptor 7JVR
TM2 47 N 2.45x45 MC4 receptor 6W25 OX2 receptor 5WQC
TM2 48 L 2.46x46 MC4 receptor 6W25 MC4 receptor 6W25
TM2 49 S 2.47x47 MC4 receptor 6W25 H1 receptor 3RZE
TM2 50 L 2.48x48 MC4 receptor 6W25 MT2 receptor 6ME7
TM2 51 G 2.49x49 MC4 receptor 6W25 ETB receptor 5X93
TM2 52 H 2.50x50 MC4 receptor 6W25 - -
TM2 53 L 2.51x51 MC4 receptor 6W25 GPR52 6LI1
TM2 54 L 2.52x52 MC4 receptor 6W25 MC4 receptor 6W25
TM2 55 L 2.53x53 MC4 receptor 6W25 D4 receptor 6IQL
TM2 56 A 2.54x54 MC4 receptor 6W25 D2 receptor 7JVR
TM2 57 A 2.55x55 D2 receptor 7JVR H1 receptor 3RZE
TM2 58 L 2.56x551 D2 receptor 7JVR D2 receptor 7JVR
TM2 59 D 2.57x56 D2 receptor 7JVR ETB receptor 6K1Q
TM2 60 M 2.58x57 MC4 receptor 6W25 D2 receptor 7JVR
TM2 61 P 2.59x58 MC4 receptor 6W25 D2 receptor 7JVR
TM2 62 F 2.60x59 MC4 receptor 6W25 MC4 receptor 6W25
TM2 63 T 2.61x60 MC4 receptor 6W25 OX2 receptor 5WQC
TM2 64 L 2.62x61 MC4 receptor 6W25 5-HT2C receptor 6BQH
TM2 65 L 2.63x62 MC4 receptor 6W25 GPR52 6LI1
TM2 66 G 2.64x63 MC4 receptor 6W25 - -
TM2 67 V 2.65x64 MC4 receptor 6W25 β1-adrenoceptor 7BVQ
TM2 68 M 2.66x65 MC4 receptor 6W25 5-HT2B receptor 5TVN
TM2 69 R 2.67x66 MC4 receptor 6W25 apelin receptor 5VBL
TM2 70 G 2.68x67 MC4 receptor 6W25 D2 receptor 7JVR
ECL1 71 R - - - - -
ECL1 72 T - D2 receptor 7JVR - -
ECL1 73 P - D2 receptor 7JVR - -
ECL1 74 S - - - - -
TM3 75 A 3.21x21 MC4 receptor 6W25 - -
TM3 76 P 3.22x22 MC4 receptor 6W25 D4 receptor 5WIV
TM3 77 G 3.23x23 MC4 receptor 6W25 - -
TM3 78 A 3.24x24 MC4 receptor 6W25 M5 receptor 6OL9
TM3 79 C 3.25x25 MC4 receptor 6W25 GPR52 6LI1
TM3 80 Q 3.26x26 MC4 receptor 6W25 GPR52 6LI1
TM3 81 V 3.27x27 MC4 receptor 6W25 MC4 receptor 6W25
TM3 82 I 3.28x28 MC4 receptor 6W25 MC4 receptor 6W25
TM3 83 G 3.29x29 MC4 receptor 6W25 GPR52 6LI1
TM3 84 F 3.30x30 MC4 receptor 6W25 MT1 receptor 6ME2
TM3 85 L 3.31x31 MC4 receptor 6W25 D2 receptor 7JVR
TM3 86 D 3.32x32 MC4 receptor 6W25 D2 receptor 7JVR
TM3 87 T 3.33x33 MC4 receptor 6W25 OX2 receptor 5WQC
TM3 88 F 3.34x34 MC4 receptor 6W25 AT1 receptor 4ZUD
TM3 89 L 3.35x35 MC4 receptor 6W25 GPR52 6LI1
TM3 90 A 3.36x36 MC4 receptor 6W25 A2A receptor 5IU4
TM3 91 S 3.37x37 MC4 receptor 6W25 GPR52 6LI1
TM3 92 N 3.38x38 MC4 receptor 6W25 - -
TM3 93 A 3.39x39 MC4 receptor 6W25 A2A receptor 5WF6
TM3 94 A 3.40x40 MC4 receptor 6W25 D2 receptor 6LUQ
TM3 95 L 3.41x41 MC4 receptor 6W25 D2 receptor 7JVR
TM3 96 S 3.42x42 MC4 receptor 6W25 MC4 receptor 6W25
TM3 97 V 3.43x43 MC4 receptor 6W25 H1 receptor 3RZE
TM3 98 A 3.44x44 MC4 receptor 6W25 GPR52 6LI1
TM3 99 A 3.45x45 MC4 receptor 6W25 D2 receptor 7JVR
TM3 100 L 3.46x46 MC4 receptor 6W25 β3-adrenoceptor 7DH5
TM3 101 S 3.47x47 MC4 receptor 6W25 GPR52 6LI1
TM3 102 A 3.48x48 MC4 receptor 6W25 P2Y1 receptor 4XNW
TM3 103 D 3.49x49 MC4 receptor 6W25 MC4 receptor 6W25
TM3 104 Q 3.50x50 MC4 receptor 6W25 - -
TM3 105 W 3.51x51 MC4 receptor 6W25 OX2 receptor 5WQC
TM3 106 L 3.52x52 MC4 receptor 6W25 GPR52 6LI1
TM3 107 A 3.53x53 MC4 receptor 6W25 GPR52 6LI1
TM3 108 V 3.54x54 MC4 receptor 6W25 D2 receptor 7JVR
TM3 109 G 3.55x55 MC4 receptor 6W25 EP2 receptor 7CX2
TM3 110 F 3.56x56 MC4 receptor 6W25 ghrelin receptor 6KO5
ICL2 111 P 34.50x50 - - - -
ICL2 112 L 34.51x51 5-HT1F receptor 7EXD MC4 receptor 6W25
ICL2 113 R 34.52x52 5-HT1F receptor 7EXD D1 receptor 7JVQ
ICL2 114 Y 34.53x53 5-HT1F receptor 7EXD 5-HT1F receptor 7EXD
ICL2 115 A 34.54x54 5-HT1F receptor 7EXD 5-HT1F receptor 7EXD
ICL2 116 G 34.55x55 5-HT1F receptor 7EXD A2A receptor 4UHR
ICL2 117 R 34.56x56 5-HT1F receptor 7EXD 5-HT1D receptor 7E32
ICL2 118 L 34.57x57 - - - -
TM4 119 R 4.38x38 MC4 receptor 6W25 OT receptor 6TPK
TM4 120 P 4.39x39 MC4 receptor 6W25 GPR52 6LI1
TM4 121 R 4.40x40 MC4 receptor 6W25 D2 receptor 7JVR
TM4 122 Y 4.41x41 MC4 receptor 6W25 CCR9 5LWE
TM4 123 A 4.42x42 MC4 receptor 6W25 5-HT1F receptor 7EXD
TM4 124 G 4.43x43 MC4 receptor 6W25 MC4 receptor 6W25
TM4 125 L 4.44x44 MC4 receptor 6W25 5-ht1E receptor 7E33
TM4 126 L 4.45x45 MC4 receptor 6W25 D1 receptor 7JVQ
TM4 127 L 4.46x46 MC4 receptor 6W25 CB2 receptor 5ZTY
TM4 128 G 4.47x47 MC4 receptor 6W25 D4 receptor 5WIV
TM4 129 C 4.48x48 MC4 receptor 6W25 MC4 receptor 6W25
TM4 130 A 4.49x49 MC4 receptor 6W25 D1 receptor 7JVQ
TM4 131 W 4.50x50 MC4 receptor 6W25 MC4 receptor 6W25
TM4 132 G 4.51x51 MC4 receptor 6W25 CXCR2 6LFL
TM4 133 Q 4.52x52 MC4 receptor 6W25 - -
TM4 134 S 4.53x53 MC4 receptor 6W25 GPR52 6LI1
TM4 135 L 4.54x54 MC4 receptor 6W25 MT1 receptor 6ME2
TM4 136 A 4.55x55 MC4 receptor 6W25 D4 receptor 6IQL
TM4 137 F 4.56x56 MC4 receptor 6W25 EP3 receptor 6AK3
TM4 138 S 4.57x57 MC4 receptor 6W25 D2 receptor 7JVR
TM4 139 G 4.58x58 MC4 receptor 6W25 S1P1 receptor 3V2Y
TM4 140 A 4.59x59 MC4 receptor 6W25 D4 receptor 5WIV
TM4 141 A 4.60x60 MC4 receptor 6W25 M5 receptor 6OL9
TM4 142 L 4.61x61 MC4 receptor 6W25 D2 receptor 7JVR
TM4 143 G 4.62x62 MC4 receptor 6W25 NK1 receptor 6HLP
TM4 144 C 4.63x63 MC4 receptor 6W25 D4 receptor 5WIV
ECL2 145 S - - - - -
ECL2 146 W - 5-HT2A receptor 6WH4 - -
ECL2 147 L - 5-HT2A receptor 6WH4 - -
ECL2 148 G - 5-HT2A receptor 6WH4 - -
ECL2 149 Y - 5-HT2A receptor 6WH4 - -
ECL2 150 S - 5-HT2A receptor 6WH4 - -
ECL2 151 S - 5-HT2A receptor 6WH4 - -
ECL2 152 A - 5-HT2A receptor 6WH4 - -
ECL2 153 F - 5-HT2A receptor 6WH4 - -
ECL2 154 A - - - - -
ECL2 155 S - - - - -
ECL2 156 C 45.50x50 D2 receptor 7JVR D2 receptor 7JVR
ECL2 157 S 45.51x51 D2 receptor 7JVR D3 receptor 7CMV
ECL2 158 L 45.52x52 D2 receptor 7JVR D4 receptor 5WIV
ECL2 159 R - - - - -
ECL2 160 L - - - - -
ECL2 161 P - - - - -
ECL2 162 P - - - - -
ECL2 163 E - - - - -
ECL2 164 P - - - - -
ECL2 165 E - - - - -
ECL2 166 R - - - - -
ECL2 167 P - - - - -
ECL2 168 R - - - - -
TM5 169 F 5.35x36 MC4 receptor 6W25 5-HT2B receptor 5TUD
TM5 170 A 5.36x37 MC4 receptor 6W25 α2B-adrenoceptor 6K42
TM5 171 A 5.37x38 MC4 receptor 6W25 MC4 receptor 6W25
TM5 172 F 5.38x39 MC4 receptor 6W25 D2 receptor 7JVR
TM5 173 T 5.39x40 MC4 receptor 6W25 5-HT1F receptor 7EXD
TM5 174 A 5.40x41 MC4 receptor 6W25 MT2 receptor 6ME7
TM5 175 T 5.41x42 MC4 receptor 6W25 AT1 receptor 4ZUD
TM5 176 L 5.42x43 MC4 receptor 6W25 MC4 receptor 6W25
TM5 177 H 5.43x44 MC4 receptor 6W25 - -
TM5 178 A 5.44x45 MC4 receptor 6W25 - -
TM5 179 V 5.45x46 D2 receptor 7JVR D2 receptor 7JVR
TM5 180 G 5.46x461 D2 receptor 7JVR 5-HT2B receptor 6DRZ
TM5 181 F 5.47x47 D2 receptor 7JVR D2 receptor 7JVR
TM5 182 V 5.48x48 MC4 receptor 6W25 κ receptor 4DJH
TM5 183 L 5.49x49 MC4 receptor 6W25 D4 receptor 6IQL
TM5 184 P 5.50x50 MC4 receptor 6W25 GPR52 6LI1
TM5 185 L 5.51x51 MC4 receptor 6W25 MC4 receptor 6W25
TM5 186 A 5.52x52 MC4 receptor 6W25 MC4 receptor 6W25
TM5 187 V 5.53x53 MC4 receptor 6W25 D2 receptor 7JVR
TM5 188 L 5.54x54 MC4 receptor 6W25 5-HT1B receptor 4IAQ
TM5 189 C 5.55x55 MC4 receptor 6W25 M1 receptor 6WJC
TM5 190 L 5.56x56 MC4 receptor 6W25 D2 receptor 7JVR
TM5 191 T 5.57x57 MC4 receptor 6W25 D1 receptor 7JVQ
TM5 192 S 5.58x58 MC4 receptor 6W25 LPA6 receptor 5XSZ
TM5 193 L 5.59x59 MC4 receptor 6W25 β1-adrenoceptor 7BVQ
TM5 194 Q 5.60x60 MC4 receptor 6W25 OX2 receptor 5WQC
TM5 195 V 5.61x61 MC4 receptor 6W25 β1-adrenoceptor 7BVQ
TM5 196 H 5.62x62 MC4 receptor 6W25 - -
TM5 197 R 5.63x63 MC4 receptor 6W25 5-HT1F receptor 7EXD
TM5 198 V 5.64x64 MC4 receptor 6W25 D2 receptor 7JVR
TM5 199 A 5.65x65 D1 receptor 7JVQ D1 receptor 7JVQ
TM5 200 R 5.66x66 D1 receptor 7JVQ D2 receptor 7JVR
TM5 201 R 5.67x67 D1 receptor 7JVQ GPR52 6LI1
TM5 202 H 5.68x68 D1 receptor 7JVQ MC4 receptor 7AUE
TM5 203 C 5.69x69 D1 receptor 7JVQ EP3 receptor 6AK3
TM5 204 Q 5.70x70 D1 receptor 7JVQ β2-adrenoceptor 3SN6
TM5 205 R 5.71x71 D1 receptor 7JVQ D1 receptor 7JVQ
TM5 206 M 5.72x72 D1 receptor 7JVQ A2A receptor 4UHR
TM5 207 D 5.73x73 D1 receptor 7JVQ β2-adrenoceptor 3SN6
TM5 208 T 5.74x74 D1 receptor 7JVQ - -
TM5 209 V 5.75x75 D1 receptor 7JVQ - -
TM5 210 T 5.76x76 D1 receptor 7JVQ - -
ICL3 211 M - - - - -
ICL3 212 K - - - - -
ICL3 213 A - - - - -
ICL3 214 L - - - - -
ICL3 215 A - - - - -
ICL3 225 R - - - - -
ICL3 226 Q - - - - -
ICL3 227 R - - - - -
ICL3 228 C - - - - -
ICL3 229 L - - - - -
TM6 230 I 6.24x24 D2 receptor 6VMS OX2 receptor 7L1V
TM6 231 Q 6.25x25 D2 receptor 6VMS 5-HT2A receptor 6A94
TM6 232 Q 6.26x26 D2 receptor 6VMS α2B-adrenoceptor 6K42
TM6 233 K 6.27x27 D2 receptor 6VMS - -
TM6 234 R 6.28x28 MC4 receptor 6W25 CB2 receptor 6PT0
TM6 235 R 6.29x29 MC4 receptor 6W25 5-HT1F receptor 7EXD
TM6 236 R 6.30x30 MC4 receptor 6W25 OX2 receptor 5WQC
TM6 237 H 6.31x31 MC4 receptor 6W25 β2-adrenoceptor 2RH1
TM6 238 R 6.32x32 MC4 receptor 6W25 GPR52 6LI1
TM6 239 A 6.33x33 MC4 receptor 6W25 D2 receptor 7JVR
TM6 240 T 6.34x34 MC4 receptor 6W25 D2 receptor 7JVR
TM6 241 R 6.35x35 MC4 receptor 6W25 5-ht1E receptor 7E33
TM6 242 K 6.36x36 MC4 receptor 6W25 PAR2 5NDD
TM6 243 I 6.37x37 MC4 receptor 6W25 M2 receptor 5YC8
TM6 244 G 6.38x38 MC4 receptor 6W25 5-HT1F receptor 7EXD
TM6 245 I 6.39x39 MC4 receptor 6W25 MC4 receptor 6W25
TM6 246 A 6.40x40 MC4 receptor 6W25 succinate receptor 6RNK
TM6 247 I 6.41x41 MC4 receptor 6W25 MC4 receptor 6W25
TM6 248 A 6.42x42 MC4 receptor 6W25 H1 receptor 3RZE
TM6 249 T 6.43x43 MC4 receptor 6W25 β3-adrenoceptor 7DH5
TM6 250 F 6.44x44 MC4 receptor 6W25 MC4 receptor 6W25
TM6 251 L 6.45x45 MC4 receptor 6W25 D4 receptor 6IQL
TM6 252 I 6.46x46 MC4 receptor 6W25 D2 receptor 7JVR
TM6 253 C 6.47x47 MC4 receptor 6W25 MC4 receptor 6W25
TM6 254 F 6.48x48 MC4 receptor 6W25 MT1 receptor 6ME2
TM6 255 A 6.49x49 MC4 receptor 6W25 MC4 receptor 6W25
TM6 256 P 6.50x50 MC4 receptor 6W25 MC4 receptor 6W25
TM6 257 Y 6.51x51 MC4 receptor 6W25 GPR52 6LI1
TM6 258 V 6.52x52 MC4 receptor 6W25 EP4 receptor 5YWY
TM6 259 M 6.53x53 MC4 receptor 6W25 CCR6 6WWZ
TM6 260 T 6.54x54 MC4 receptor 6W25 D2 receptor 7JVR
TM6 261 R 6.55x55 MC4 receptor 6W25 ghrelin receptor 6KO5
TM6 262 L 6.56x56 MC4 receptor 6W25 GPR52 6LI1
TM6 263 A 6.57x57 MC4 receptor 6W25 MT1 receptor 6ME2
TM6 264 E 6.58x58 MC4 receptor 6W25 GPR52 6LI0
TM6 265 L 6.59x59 MC4 receptor 6W25 A1 receptor 5UEN
TM6 266 V 6.60x60 MC4 receptor 6W25 5-HT1F receptor 7EXD
TM6 267 P 6.61x61 MC4 receptor 6W25 - -
ECL3 268 F - - - - -
ECL3 269 V - D2 receptor 7JVR - -
ECL3 270 T - D2 receptor 7JVR - -
ECL3 271 V - - - - -
TM7 272 N 7.31x30 D2 receptor 7JVR GPR52 6LI1
TM7 273 A 7.32x31 D2 receptor 7JVR OT receptor 6TPK
TM7 274 Q 7.33x32 D2 receptor 7JVR CCR5 7O7F
TM7 275 W 7.34x33 MC4 receptor 6W25 OX2 receptor 5WQC
TM7 276 G 7.35x34 MC4 receptor 6W25 5-HT1A receptor 7E2X
TM7 277 I 7.36x35 MC4 receptor 6W25 β2-adrenoceptor 3SN6
TM7 278 L 7.37x36 MC4 receptor 6W25 MC4 receptor 6W25
TM7 279 S 7.38x37 MC4 receptor 6W25 MT1 receptor 6ME2
TM7 280 K 7.39x38 MC4 receptor 6W25 - -
TM7 281 C 7.40x39 MC4 receptor 6W25 apelin receptor 5VBL
TM7 282 L 7.41x40 MC4 receptor 6W25 MC4 receptor 6W25
TM7 283 T 7.42x41 MC4 receptor 6W25 A1 receptor 5UEN
TM7 284 Y 7.43x42 MC4 receptor 6W25 D2 receptor 7JVR
TM7 285 S 7.44x43 MC4 receptor 6W25 GPR52 6LI1
TM7 286 K 7.45x45 MC4 receptor 6W25 - -
TM7 287 A 7.46x46 MC4 receptor 6W25 ghrelin receptor 6KO5
TM7 288 V 7.47x47 MC4 receptor 6W25 A2A receptor 4UHR
TM7 289 A 7.48x48 MC4 receptor 6W25 OX2 receptor 5WQC
TM7 290 D 7.49x49 MC4 receptor 6W25 MC4 receptor 7AUE
TM7 291 P 7.50x50 MC4 receptor 6W25 MC4 receptor 6W25
TM7 292 F 7.51x51 MC4 receptor 6W25 A2A receptor 4UHR
TM7 293 T 7.52x52 MC4 receptor 6W25 - -
TM7 294 Y 7.53x53 MC4 receptor 6W25 MC4 receptor 6W25
TM7 295 S 7.54x54 MC4 receptor 6W25 GPR52 6LI3
TM7 296 L 7.55x55 MC4 receptor 6W25 MC4 receptor 6W25
TM7 297 L 7.56x56 MC4 receptor 6W25 MT1 receptor 6ME2
H8 298 R 8.47x47 MC4 receptor 6W25 EP2 receptor 7CX2
H8 299 R 8.48x48 MC4 receptor 6W25 A2A receptor 4UHR
H8 300 P 8.49x49 MC4 receptor 6W25 EP2 receptor 7CX2
H8 301 F 8.50x50 MC4 receptor 6W25 GPR52 6LI1
H8 302 R 8.51x51 MC4 receptor 6W25 MC4 receptor 6W25
H8 303 Q 8.52x52 MC4 receptor 6W25 5-HT1D receptor 7E32
H8 304 V 8.53x53 MC4 receptor 6W25 D4 receptor 5WIV
H8 305 L 8.54x54 MC4 receptor 6W25 GPR52 6LI1
H8 306 A 8.55x55 MC4 receptor 6W25 - -
H8 307 G 8.56x56 MC4 receptor 6W25 β1-adrenoceptor 7BVQ
H8 308 M 8.57x57 MC4 receptor 6W25 apelin receptor 5VBL
H8 309 V 8.58x58 MC4 receptor 6W25 5-HT1D receptor 7E32
H8 310 H 8.59x59 MC4 receptor 6W25 D2 receptor 6VMS
C-term 311 R - - - - -
C-term 312 L - - - - -
C-term 313 L - - - - -
C-term 314 K - - - - -
C-term 315 R - - - - -