MCH2 receptor homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Intermediate
VERSION
2022-06-19
MODEL
TEMPLATES
5NDD (PAR2)
7M8W (DP2 receptor)
7T11 (SST2 receptor)
7T10 (SST2 receptor)
7WQ3 (GAL1 receptor)
6LW5 (FPR2/ALX)
6Z8N (NTS1 receptor)
7E2X (5-HT1A receptor)
7E32 (5-HT1D receptor)
4N6H (δ receptor)
None
7M8W (DP2 receptor)
7T11 (SST2 receptor)
7T10 (SST2 receptor)
7WQ3 (GAL1 receptor)
6LW5 (FPR2/ALX)
6Z8N (NTS1 receptor)
7E2X (5-HT1A receptor)
7E32 (5-HT1D receptor)
4N6H (δ receptor)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 78.5 | 13.9 | 7.6 |
| Side-chains | 21.9 | 60.6 | 17.5 |
Number of backbone templates: 10
Number of rotamer templates: 55
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 26 | Y | - | PAR2 | 5NDD | PAR2 | 5NDD |
| N-term | 27 | Q | - | PAR2 | 5NDD | PAR2 | 5NDD |
| N-term | 28 | T | - | PAR2 | 5NDD | PAR2 | 5NDD |
| N-term | 29 | A | - | PAR2 | 5NDD | PAR2 | 5NDD |
| N-term | 30 | S | - | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 31 | V | 1.29x29 | PAR2 | 5NDD | - | - |
| TM1 | 32 | V | 1.30x30 | PAR2 | 5NDD | μ receptor | 4DKL |
| TM1 | 33 | D | 1.31x31 | PAR2 | 5NDD | - | - |
| TM1 | 34 | T | 1.32x32 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 35 | V | 1.33x33 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 36 | I | 1.34x34 | PAR2 | 5NDD | κ receptor | 4DJH |
| TM1 | 37 | L | 1.35x35 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 38 | P | 1.36x36 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 39 | S | 1.37x37 | PAR2 | 5NDD | - | - |
| TM1 | 40 | M | 1.38x38 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM1 | 41 | I | 1.39x39 | PAR2 | 5NDD | B1 receptor | 7EIB |
| TM1 | 42 | G | 1.40x40 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| TM1 | 43 | I | 1.41x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 44 | I | 1.42x42 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| TM1 | 45 | C | 1.43x43 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM1 | 46 | S | 1.44x44 | PAR2 | 5NDD | S1P3 receptor | 7EW4 |
| TM1 | 47 | T | 1.45x45 | PAR2 | 5NDD | CXCR4 | 3ODU |
| TM1 | 48 | G | 1.46x46 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM1 | 49 | L | 1.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 50 | V | 1.48x48 | PAR2 | 5NDD | κ receptor | 4DJH |
| TM1 | 51 | G | 1.49x49 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM1 | 52 | N | 1.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 53 | I | 1.51x51 | PAR2 | 5NDD | B2 receptor | 7F2O |
| TM1 | 54 | L | 1.52x52 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM1 | 55 | I | 1.53x53 | PAR2 | 5NDD | CCK2 receptor | 7F8W |
| TM1 | 56 | V | 1.54x54 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM1 | 57 | F | 1.55x55 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM1 | 58 | T | 1.56x56 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM1 | 59 | I | 1.57x57 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM1 | 60 | I | 1.58x58 | PAR2 | 5NDD | κ receptor | 6B73 |
| TM1 | 61 | R | 1.59x59 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM1 | 62 | S | 1.60x60 | PAR2 | 5NDD | EP4 receptor | 7D7M |
| ICL1 | 63 | R | - | - | - | - | - |
| ICL1 | 64 | K | - | DP2 receptor | 7M8W | - | - |
| ICL1 | 65 | K | - | - | - | - | - |
| TM2 | 66 | T | 2.37x37 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM2 | 67 | V | 2.38x38 | PAR2 | 5NDD | B2 receptor | 7F2O |
| TM2 | 68 | P | 2.39x39 | PAR2 | 5NDD | ETB receptor | 5X93 |
| TM2 | 69 | D | 2.40x40 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM2 | 70 | I | 2.41x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 71 | Y | 2.42x42 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 72 | I | 2.43x43 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM2 | 73 | C | 2.44x44 | PAR2 | 5NDD | 5-HT1E receptor | 7E33 |
| TM2 | 74 | N | 2.45x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 75 | L | 2.46x46 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 76 | A | 2.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 77 | V | 2.48x48 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM2 | 78 | A | 2.49x49 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 79 | D | 2.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 80 | L | 2.51x51 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 81 | V | 2.52x52 | PAR2 | 5NDD | β1-adrenoceptor | 7BVQ |
| TM2 | 82 | H | 2.53x53 | PAR2 | 5NDD | ETB receptor | 5X93 |
| TM2 | 83 | I | 2.54x54 | PAR2 | 5NDD | GAL2 receptor | 7WQ4 |
| TM2 | 84 | V | 2.55x55 | PAR2 | 5NDD | CCK2 receptor | 7F8W |
| TM2 | 85 | G | 2.56x56 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM2 | 86 | M | 2.57x57 | PAR2 | 5NDD | κ receptor | 4DJH |
| TM2 | 87 | P | 2.58x58 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 88 | F | 2.59x59 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM2 | 89 | L | 2.60x60 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM2 | 90 | I | 2.61x61 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 91 | H | 2.62x62 | PAR2 | 5NDD | CCR5 | 4MBS |
| TM2 | 92 | Q | 2.63x63 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM2 | 93 | W | 2.64x64 | PAR2 | 5NDD | - | - |
| TM2 | 94 | A | 2.65x65 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM2 | 95 | R | 2.66x66 | PAR2 | 5NDD | apelin receptor | 5VBL |
| ECL1 | 96 | G | - | - | - | - | - |
| ECL1 | 97 | G | - | - | - | - | - |
| ECL1 | 98 | E | 23.49x49 | SST2 receptor | 7T11 | D2 receptor | 7JVR |
| ECL1 | 99 | W | 23.50x50 | SST2 receptor | 7T11 | SST2 receptor | 7T11 |
| ECL1 | 100 | V | 23.51x51 | SST2 receptor | 7T11 | GAL1 receptor | 7WQ3 |
| ECL1 | 101 | F | 23.52x52 | - | - | - | - |
| TM3 | 102 | G | 3.21x21 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 103 | G | 3.22x22 | PAR2 | 5NDD | D1 receptor | 7JVQ |
| TM3 | 104 | P | 3.23x23 | PAR2 | 5NDD | H1 receptor | 3RZE |
| TM3 | 105 | L | 3.24x24 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 106 | C | 3.25x25 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 107 | T | 3.26x26 | PAR2 | 5NDD | US28 | 5WB1 |
| TM3 | 108 | I | 3.27x27 | PAR2 | 5NDD | μ receptor | 4DKL |
| TM3 | 109 | I | 3.28x28 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| TM3 | 110 | T | 3.29x29 | PAR2 | 5NDD | β1-adrenoceptor | 7BVQ |
| TM3 | 111 | S | 3.30x30 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM3 | 112 | L | 3.31x31 | PAR2 | 5NDD | CCK2 receptor | 7F8W |
| TM3 | 113 | D | 3.32x32 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM3 | 114 | T | 3.33x33 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| TM3 | 115 | C | 3.34x34 | PAR2 | 5NDD | MRGPRX2 | 7VDL |
| TM3 | 116 | N | 3.35x35 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 117 | Q | 3.36x36 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM3 | 118 | F | 3.37x37 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM3 | 119 | A | 3.38x38 | PAR2 | 5NDD | GAL2 receptor | 7WQ4 |
| TM3 | 120 | C | 3.39x39 | PAR2 | 5NDD | CCR9 | 5LWE |
| TM3 | 121 | S | 3.40x40 | PAR2 | 5NDD | GAL2 receptor | 7WQ4 |
| TM3 | 122 | A | 3.41x41 | PAR2 | 5NDD | LPA1 receptor | 4Z35 |
| TM3 | 123 | I | 3.42x42 | PAR2 | 5NDD | EP4 receptor | 5YWY |
| TM3 | 124 | M | 3.43x43 | PAR2 | 5NDD | GPR183 | 7TUZ |
| TM3 | 125 | T | 3.44x44 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 126 | V | 3.45x45 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM3 | 127 | M | 3.46x46 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM3 | 128 | S | 3.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 129 | V | 3.48x48 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 130 | D | 3.49x49 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM3 | 131 | R | 3.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 132 | Y | 3.51x51 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM3 | 133 | F | 3.52x52 | PAR2 | 5NDD | ghrelin receptor | 7NA7 |
| TM3 | 134 | A | 3.53x53 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM3 | 135 | L | 3.54x54 | PAR2 | 5NDD | B2 receptor | 7F2O |
| TM3 | 136 | V | 3.55x55 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 137 | Q | 3.56x56 | PAR2 | 5NDD | H1 receptor | 3RZE |
| ICL2 | 138 | P | 34.50x50 | - | - | - | - |
| ICL2 | 139 | F | 34.51x51 | SST2 receptor | 7T10 | NTS1 receptor | 6OSA |
| ICL2 | 140 | R | 34.52x52 | SST2 receptor | 7T10 | GAL1 receptor | 7WQ3 |
| ICL2 | 141 | L | 34.53x53 | SST2 receptor | 7T10 | - | - |
| ICL2 | 142 | T | 34.54x54 | SST2 receptor | 7T10 | - | - |
| ICL2 | 143 | R | 34.55x55 | SST2 receptor | 7T10 | CCR1 | 7VL9 |
| ICL2 | 144 | W | 34.56x56 | SST2 receptor | 7T10 | SST2 receptor | 7T10 |
| ICL2 | 145 | R | 34.57x57 | - | - | - | - |
| TM4 | 146 | T | 4.38x38 | PAR2 | 5NDD | κ receptor | 4DJH |
| TM4 | 147 | R | 4.39x39 | PAR2 | 5NDD | CCK2 receptor | 7F8W |
| TM4 | 148 | Y | 4.40x40 | PAR2 | 5NDD | CXCR2 | 6LFL |
| TM4 | 149 | K | 4.41x41 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM4 | 150 | T | 4.42x42 | PAR2 | 5NDD | NTS1 receptor | 6OSA |
| TM4 | 151 | I | 4.43x43 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 152 | R | 4.44x44 | PAR2 | 5NDD | CCK2 receptor | 7F8W |
| TM4 | 153 | I | 4.45x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 154 | N | 4.46x46 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM4 | 155 | L | 4.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 156 | G | 4.48x48 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM4 | 157 | L | 4.49x49 | PAR2 | 5NDD | apelin receptor | 5VBL |
| TM4 | 158 | W | 4.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 159 | A | 4.51x51 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| TM4 | 160 | A | 4.52x52 | PAR2 | 5NDD | NTS1 receptor | 6OSA |
| TM4 | 161 | S | 4.53x53 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM4 | 162 | F | 4.54x54 | PAR2 | 5NDD | H1 receptor | 3RZE |
| TM4 | 163 | I | 4.55x55 | PAR2 | 5NDD | M2 receptor | 5YC8 |
| TM4 | 164 | L | 4.56x56 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM4 | 165 | A | 4.57x57 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| TM4 | 166 | L | 4.58x59 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM4 | 167 | P | 4.59x60 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 168 | V | 4.60x61 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| TM4 | 169 | W | 4.61x62 | PAR2 | 5NDD | - | - |
| TM4 | 170 | V | 4.62x63 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 171 | Y | 4.63x64 | GAL1 receptor | 7WQ3 | SST2 receptor | 7T10 |
| TM4 | 172 | S | 4.64x65 | GAL1 receptor | 7WQ3 | CCR1 | 7VL9 |
| ECL2 | 173 | K | - | - | - | - | - |
| ECL2 | 174 | V | - | FPR2/ALX | 6LW5 | - | - |
| ECL2 | 175 | I | - | FPR2/ALX | 6LW5 | - | - |
| ECL2 | 176 | K | - | FPR2/ALX | 6LW5 | - | - |
| ECL2 | 177 | F | - | FPR2/ALX | 6LW5 | - | - |
| ECL2 | 178 | K | - | FPR2/ALX | 6LW5 | - | - |
| ECL2 | 179 | D | - | FPR2/ALX | 6LW5 | - | - |
| ECL2 | 180 | G | - | FPR2/ALX | 6LW5 | FPR2/ALX | 6LW5 |
| ECL2 | 181 | V | - | FPR2/ALX | 6LW5 | - | - |
| ECL2 | 182 | E | - | FPR2/ALX | 6LW5 | - | - |
| ECL2 | 183 | S | - | - | - | - | - |
| ECL2 | 184 | C | 45.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| ECL2 | 185 | A | 45.51x51 | PAR2 | 5NDD | GPR52 | 6LI1 |
| ECL2 | 186 | F | 45.52x52 | PAR2 | 5NDD | β2-adrenoceptor | 5D5A |
| ECL2 | 187 | D | - | - | - | - | - |
| ECL2 | 188 | L | - | GAL1 receptor | 7WQ3 | - | - |
| ECL2 | 189 | T | - | - | - | - | - |
| TM5 | 190 | S | 5.31x32 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM5 | 191 | P | 5.32x33 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| TM5 | 192 | D | 5.33x34 | PAR2 | 5NDD | - | - |
| TM5 | 193 | D | 5.34x35 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 194 | V | 5.35x36 | PAR2 | 5NDD | NTS1 receptor | 6OSA |
| TM5 | 195 | L | 5.36x37 | PAR2 | 5NDD | κ receptor | 4DJH |
| TM5 | 196 | W | 5.37x38 | PAR2 | 5NDD | H1 receptor | 3RZE |
| TM5 | 197 | Y | 5.38x39 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 198 | T | 5.39x40 | PAR2 | 5NDD | CCR5 | 4MBS |
| TM5 | 199 | L | 5.40x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 200 | Y | 5.41x42 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM5 | 201 | L | 5.42x43 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 202 | T | 5.43x44 | PAR2 | 5NDD | NTS1 receptor | 6OSA |
| TM5 | 203 | I | 5.44x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 204 | T | 5.45x46 | PAR2 | 5NDD | BLT1 receptor | 7K15 |
| TM5 | 205 | T | 5.46x461 | PAR2 | 5NDD | OX2 receptor | 5WQC |
| TM5 | 206 | F | 5.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 207 | F | 5.48x48 | PAR2 | 5NDD | CCK2 receptor | 7F8W |
| TM5 | 208 | F | 5.49x49 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 209 | P | 5.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 210 | L | 5.51x51 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM5 | 211 | P | 5.52x52 | PAR2 | 5NDD | D4 receptor | 5WIV |
| TM5 | 212 | L | 5.53x53 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 213 | I | 5.54x54 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM5 | 214 | L | 5.55x55 | PAR2 | 5NDD | H1 receptor | 3RZE |
| TM5 | 215 | V | 5.56x56 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM5 | 216 | C | 5.57x57 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM5 | 217 | Y | 5.58x58 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 218 | I | 5.59x59 | PAR2 | 5NDD | D2 receptor | 7JVR |
| TM5 | 219 | L | 5.60x60 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 220 | I | 5.61x61 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM5 | 221 | L | 5.62x62 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM5 | 222 | C | 5.63x63 | PAR2 | 5NDD | GPR183 | 7TUZ |
| TM5 | 223 | Y | 5.64x64 | PAR2 | 5NDD | GAL2 receptor | 7WQ4 |
| TM5 | 224 | T | 5.65x65 | PAR2 | 5NDD | M3 receptor | 5ZHP |
| TM5 | 225 | W | 5.66x66 | NTS1 receptor | 6Z8N | GAL2 receptor | 7WQ4 |
| TM5 | 226 | E | 5.67x67 | NTS1 receptor | 6Z8N | Rhodopsin | 5W0P |
| TM5 | 227 | M | 5.68x68 | NTS1 receptor | 6Z8N | NTS1 receptor | 6Z8N |
| TM5 | 228 | Y | 5.69x69 | NTS1 receptor | 6Z8N | AT1 receptor | 6DO1 |
| TM5 | 229 | Q | 5.70x70 | NTS1 receptor | 6Z8N | β2-adrenoceptor | 3SN6 |
| TM5 | 230 | Q | 5.71x71 | NTS1 receptor | 6Z8N | NTS1 receptor | 6Z8N |
| TM5 | 231 | N | 5.72x72 | NTS1 receptor | 6Z8N | - | - |
| TM5 | 232 | K | 5.73x73 | NTS1 receptor | 6Z8N | MT1 receptor | 7VGY |
| ICL3 | 233 | D | - | - | - | - | - |
| ICL3 | 234 | A | - | - | - | - | - |
| ICL3 | 235 | R | - | - | - | - | - |
| ICL3 | 236 | C | - | - | - | - | - |
| ICL3 | 237 | C | - | - | - | - | - |
| TM6 | 238 | N | 6.22x22 | 5-HT1A receptor | 7E2X | - | - |
| TM6 | 239 | P | 6.23x23 | 5-HT1A receptor | 7E2X | - | - |
| TM6 | 240 | S | 6.24x24 | 5-HT1A receptor | 7E2X | GAL2 receptor | 7WQ4 |
| TM6 | 241 | V | 6.25x25 | 5-HT1A receptor | 7E2X | M5 receptor | 6OL9 |
| TM6 | 242 | P | 6.26x26 | 5-HT1A receptor | 7E2X | - | - |
| TM6 | 243 | K | 6.27x27 | PAR2 | 5NDD | MT1 receptor | 7VGZ |
| TM6 | 244 | Q | 6.28x28 | PAR2 | 5NDD | NTS1 receptor | 6OSA |
| TM6 | 245 | R | 6.29x29 | PAR2 | 5NDD | H1 receptor | 3RZE |
| TM6 | 246 | V | 6.30x30 | PAR2 | 5NDD | V2 receptor | 7KH0 |
| TM6 | 247 | M | 6.31x31 | PAR2 | 5NDD | LPA1 receptor | 4Z35 |
| TM6 | 248 | K | 6.32x32 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 249 | L | 6.33x33 | PAR2 | 5NDD | apelin receptor | 5VBL |
| TM6 | 250 | T | 6.34x34 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM6 | 251 | K | 6.35x35 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM6 | 252 | M | 6.36x36 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM6 | 253 | V | 6.37x37 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM6 | 254 | L | 6.38x38 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM6 | 255 | V | 6.39x39 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 256 | L | 6.40x40 | PAR2 | 5NDD | apelin receptor | 5VBL |
| TM6 | 257 | V | 6.41x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 258 | V | 6.42x42 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| TM6 | 259 | V | 6.43x43 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM6 | 260 | F | 6.44x44 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM6 | 261 | I | 6.45x45 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM6 | 262 | L | 6.46x46 | SST2 receptor | 7T10 | CCR1 | 7VL9 |
| TM6 | 263 | S | 6.47x47 | SST2 receptor | 7T10 | GAL1 receptor | 7WQ3 |
| TM6 | 264 | A | 6.48x48 | PAR2 | 5NDD | - | - |
| TM6 | 265 | A | 6.49x49 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM6 | 266 | P | 6.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 267 | Y | 6.51x51 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM6 | 268 | H | 6.52x52 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM6 | 269 | V | 6.53x53 | PAR2 | 5NDD | NOP receptor | 5DHG |
| TM6 | 270 | I | 6.54x54 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| TM6 | 271 | Q | 6.55x55 | PAR2 | 5NDD | Y2 receptor | 7DDZ |
| TM6 | 272 | L | 6.56x56 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| TM6 | 273 | V | 6.57x57 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 274 | N | 6.58x58 | PAR2 | 5NDD | CCR5 | 4MBS |
| TM6 | 275 | L | 6.59x59 | PAR2 | 5NDD | ETB receptor | 5X93 |
| TM6 | 276 | Q | 6.60x60 | PAR2 | 5NDD | - | - |
| TM6 | 277 | M | 6.61x61 | PAR2 | 5NDD | CXCR2 | 6LFL |
| ECL3 | 278 | E | - | - | - | - | - |
| ECL3 | 279 | Q | - | 5-HT1D receptor | 7E32 | - | - |
| ECL3 | 280 | P | - | 5-HT1D receptor | 7E32 | - | - |
| ECL3 | 281 | T | - | 5-HT1D receptor | 7E32 | - | - |
| ECL3 | 282 | L | - | 5-HT1D receptor | 7E32 | - | - |
| ECL3 | 283 | A | - | - | - | - | - |
| TM7 | 284 | F | 7.31x30 | PAR2 | 5NDD | GPR183 | 7TUZ |
| TM7 | 285 | Y | 7.32x31 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 286 | V | 7.33x32 | PAR2 | 5NDD | μ receptor | 4DKL |
| TM7 | 287 | G | 7.34x33 | PAR2 | 5NDD | B1 receptor | 7EIB |
| TM7 | 288 | Y | 7.35x34 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 289 | Y | 7.36x35 | PAR2 | 5NDD | κ receptor | 4DJH |
| TM7 | 290 | L | 7.37x36 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM7 | 291 | S | 7.38x37 | PAR2 | 5NDD | GAL2 receptor | 7WQ4 |
| TM7 | 292 | I | 7.39x38 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM7 | 293 | C | 7.40x39 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 294 | L | 7.41x40 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 295 | S | 7.42x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 296 | Y | 7.43x42 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM7 | 297 | A | 7.44x43 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM7 | 298 | S | 7.45x45 | PAR2 | 5NDD | CCK2 receptor | 7F8W |
| TM7 | 299 | S | 7.46x46 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 300 | S | 7.47x47 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM7 | 301 | I | 7.48x48 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 302 | N | 7.49x49 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM7 | 303 | P | 7.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 304 | F | 7.51x51 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 305 | L | 7.52x52 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| TM7 | 306 | Y | 7.53x53 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 307 | I | 7.54x54 | PAR2 | 5NDD | EP4 receptor | 5YWY |
| TM7 | 308 | L | 7.55x55 | PAR2 | 5NDD | GAL2 receptor | 7WQ4 |
| TM7 | 309 | L | 7.56x56 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| H8 | 310 | S | 8.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| H8 | 311 | G | 8.48x48 | PAR2 | 5NDD | OX2 receptor | 5WQC |
| H8 | 312 | N | 8.49x49 | PAR2 | 5NDD | SST2 receptor | 7T10 |
| H8 | 313 | F | 8.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| H8 | 314 | Q | 8.51x51 | PAR2 | 5NDD | AT2 receptor | 5UNF |
| H8 | 315 | K | 8.52x52 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| H8 | 316 | R | 8.53x53 | PAR2 | 5NDD | FPR2/ALX | 7WVX |
| H8 | 317 | L | 8.54x54 | PAR2 | 5NDD | CCR1 | 7VL9 |
| H8 | 318 | P | 8.55x55 | PAR2 | 5NDD | - | - |
| H8 | 319 | Q | 8.56x56 | PAR2 | 5NDD | GAL1 receptor | 7WQ3 |
| H8 | 320 | I | 8.57x57 | PAR2 | 5NDD | GAL2 receptor | 7WQ4 |
| H8 | 321 | Q | 8.58x58 | PAR2 | 5NDD | - | - |
| H8 | 322 | R | 8.59x59 | δ receptor | 4N6H | AT2 receptor | 6JOD |
| C-term | 323 | R | - | - | - | - | - |
| C-term | 324 | A | - | - | - | - | - |
| C-term | 325 | T | - | - | - | - | - |
| C-term | 326 | E | - | - | - | - | - |
| C-term | 327 | K | - | - | - | - | - |