MRGPRD homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Intermediate
VERSION
2021-01-08
MODEL
TEMPLATES
6WWZ (CCR6)
5NDD (PAR2)
5O9H (C5a1 receptor)
5XSZ (LPA6 receptor)
4XNW (P2Y1 receptor)
3VG9 (A2A receptor)
None
5NDD (PAR2)
5O9H (C5a1 receptor)
5XSZ (LPA6 receptor)
4XNW (P2Y1 receptor)
3VG9 (A2A receptor)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 79.4 | 12.2 | 8.4 |
| Side-chains | 14.3 | 64.0 | 21.7 |
Number of backbone templates: 6
Number of rotamer templates: 54
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 15 | L | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| N-term | 16 | N | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| N-term | 17 | Y | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| N-term | 18 | S | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| N-term | 19 | R | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| TM1 | 20 | G | 1.25x25 | CCR6 | 6WWZ | - | - |
| TM1 | 21 | S | 1.26x26 | CCR6 | 6WWZ | - | - |
| TM1 | 22 | T | 1.27x27 | CCR6 | 6WWZ | - | - |
| TM1 | 23 | V | 1.28x28 | PAR2 | 5NDD | - | - |
| TM1 | 24 | H | 1.29x29 | PAR2 | 5NDD | - | - |
| TM1 | 25 | T | 1.30x30 | PAR2 | 5NDD | ETB receptor | 5X93 |
| TM1 | 26 | A | 1.31x31 | PAR2 | 5NDD | CCR5 | 5UIW |
| TM1 | 27 | Y | 1.32x32 | PAR2 | 5NDD | PAF receptor | 5ZKQ |
| TM1 | 28 | L | 1.33x33 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM1 | 29 | V | 1.34x34 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM1 | 30 | L | 1.35x35 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 31 | S | 1.36x36 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM1 | 32 | S | 1.37x37 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM1 | 33 | L | 1.38x38 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM1 | 34 | A | 1.39x39 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM1 | 35 | M | 1.40x40 | PAR2 | 5NDD | apelin receptor | 5VBL |
| TM1 | 36 | F | 1.41x41 | PAR2 | 5NDD | α2B-adrenoceptor | 6K41 |
| TM1 | 37 | T | 1.42x42 | PAR2 | 5NDD | FPR2/ALX | 6LW5 |
| TM1 | 38 | C | 1.43x43 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM1 | 39 | L | 1.44x44 | PAR2 | 5NDD | C5a1 receptor | 5O9H |
| TM1 | 40 | C | 1.45x45 | PAR2 | 5NDD | - | - |
| TM1 | 41 | G | 1.46x46 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM1 | 42 | M | 1.47x47 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM1 | 43 | A | 1.48x48 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM1 | 44 | G | 1.49x49 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM1 | 45 | N | 1.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 46 | S | 1.51x51 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM1 | 47 | M | 1.52x52 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 48 | V | 1.53x53 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM1 | 49 | I | 1.54x54 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM1 | 50 | W | 1.55x55 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 51 | L | 1.56x56 | PAR2 | 5NDD | AT2 receptor | 6JOD |
| TM1 | 52 | L | 1.57x57 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM1 | 53 | G | 1.58x58 | PAR2 | 5NDD | DP2 receptor | 6D27 |
| TM1 | 54 | F | 1.59x59 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 55 | R | 1.60x60 | PAR2 | 5NDD | PAR2 | 5NDD |
| ICL1 | 56 | M | - | - | - | - | |
| ICL1 | 57 | H | C5a1 receptor | 5O9H | - | - | |
| ICL1 | 58 | R | - | - | - | - | |
| TM2 | 59 | N | 2.37x37 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM2 | 60 | P | 2.38x38 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 61 | F | 2.39x39 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM2 | 62 | C | 2.40x40 | PAR2 | 5NDD | - | - |
| TM2 | 63 | I | 2.41x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 64 | Y | 2.42x42 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 65 | I | 2.43x43 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM2 | 66 | L | 2.44x44 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM2 | 67 | N | 2.45x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 68 | L | 2.46x46 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 69 | A | 2.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 70 | A | 2.48x48 | PAR2 | 5NDD | US28 | 5WB1 |
| TM2 | 71 | A | 2.49x49 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 72 | D | 2.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 73 | L | 2.51x51 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 74 | L | 2.52x52 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 75 | F | 2.53x53 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM2 | 76 | L | 2.54x54 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM2 | 77 | F | 2.55x55 | PAR2 | 5NDD | MT2 receptor | 6ME6 |
| TM2 | 78 | S | 2.56x56 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM2 | 79 | M | 2.57x57 | PAR2 | 5NDD | 5-HT2B receptor | 4IB4 |
| TM2 | 80 | A | 2.58x58 | PAR2 | 5NDD | CB2 receptor | 5ZTY |
| TM2 | 81 | S | 2.59x59 | PAR2 | 5NDD | Rhodopsin | 4ZWJ |
| TM2 | 82 | T | 2.60x60 | PAR2 | 5NDD | OX2 receptor | 5WS3 |
| TM2 | 83 | L | 2.61x61 | PAR2 | 5NDD | 5-HT2B receptor | 4IB4 |
| TM2 | 84 | S | 2.62x62 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM2 | 85 | L | 2.63x63 | PAR2 | 5NDD | S1P1 receptor | 3V2Y |
| TM2 | 86 | E | 2.64x64 | PAR2 | 5NDD | α2B-adrenoceptor | 6K41 |
| TM2 | 87 | T | 2.65x65 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM2 | 88 | Q | 2.66x66 | PAR2 | 5NDD | C5a1 receptor | 5O9H |
| ECL1 | 89 | P | - | - | - | - | |
| ECL1 | 90 | L | LPA6 receptor | 5XSZ | - | - | |
| ECL1 | 91 | V | LPA6 receptor | 5XSZ | - | - | |
| ECL1 | 92 | N | LPA6 receptor | 5XSZ | - | - | |
| ECL1 | 93 | T | - | - | - | - | |
| TM3 | 94 | T | 3.21x21 | PAR2 | 5NDD | S1P1 receptor | 3V2Y |
| TM3 | 95 | D | 3.22x22 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM3 | 96 | K | 3.23x23 | PAR2 | 5NDD | 5-HT2A receptor | 6A94 |
| TM3 | 97 | V | 3.24x24 | PAR2 | 5NDD | P2Y12 receptor | 4NTJ |
| TM3 | 98 | H | 3.25x25 | PAR2 | 5NDD | - | - |
| TM3 | 99 | E | 3.26x26 | PAR2 | 5NDD | α2B-adrenoceptor | 6K41 |
| TM3 | 100 | L | 3.27x27 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM3 | 101 | M | 3.28x28 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM3 | 102 | K | 3.29x29 | PAR2 | 5NDD | CCR6 | 6WWZ |
| TM3 | 103 | R | 3.30x30 | PAR2 | 5NDD | - | - |
| TM3 | 104 | L | 3.31x31 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM3 | 105 | M | 3.32x32 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM3 | 106 | Y | 3.33x33 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 107 | F | 3.34x34 | PAR2 | 5NDD | P2Y12 receptor | 4NTJ |
| TM3 | 108 | A | 3.35x35 | PAR2 | 5NDD | US28 | 5WB1 |
| TM3 | 109 | Y | 3.36x36 | PAR2 | 5NDD | CCR2 | 5T1A |
| TM3 | 110 | T | 3.37x37 | PAR2 | 5NDD | 5-HT2B receptor | 4IB4 |
| TM3 | 111 | V | 3.38x38 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM3 | 112 | G | 3.39x39 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM3 | 113 | L | 3.40x40 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM3 | 114 | S | 3.41x41 | PAR2 | 5NDD | P2Y12 receptor | 4NTJ |
| TM3 | 115 | L | 3.42x42 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 116 | L | 3.43x43 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 117 | T | 3.44x44 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 118 | A | 3.45x45 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM3 | 119 | I | 3.46x46 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 120 | S | 3.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 121 | T | 3.48x48 | PAR2 | 5NDD | - | - |
| TM3 | 122 | Q | 3.49x49 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 123 | R | 3.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 124 | C | 3.51x51 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM3 | 125 | L | 3.52x52 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 126 | S | 3.53x53 | PAR2 | 5NDD | AT2 receptor | 6JOD |
| TM3 | 127 | V | 3.54x54 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 128 | L | 3.55x55 | PAR2 | 5NDD | FPR2/ALX | 6LW5 |
| TM3 | 129 | F | 3.56x56 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| ICL2 | 130 | P | 34.50x50 | - | - | - | - |
| ICL2 | 131 | I | 34.51x51 | C5a1 receptor | 5O9H | C5a1 receptor | 6C1R |
| ICL2 | 132 | W | 34.52x52 | C5a1 receptor | 5O9H | C5a1 receptor | 5O9H |
| ICL2 | 133 | F | 34.53x53 | C5a1 receptor | 5O9H | - | - |
| ICL2 | 134 | K | 34.54x54 | C5a1 receptor | 5O9H | NTS1 receptor | 4XES |
| ICL2 | 135 | C | 34.55x55 | C5a1 receptor | 5O9H | - | - |
| ICL2 | 136 | H | 34.56x56 | C5a1 receptor | 5O9H | DP2 receptor | 6D27 |
| ICL2 | 137 | R | 34.57x57 | - | - | - | - |
| TM4 | 138 | P | 4.38x38 | PAR2 | 5NDD | - | - |
| TM4 | 139 | R | 4.39x39 | PAR2 | 5NDD | PAF receptor | 5ZKQ |
| TM4 | 140 | H | 4.40x40 | PAR2 | 5NDD | - | - |
| TM4 | 141 | L | 4.41x41 | PAR2 | 5NDD | C5a1 receptor | 5O9H |
| TM4 | 142 | S | 4.42x42 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM4 | 143 | A | 4.43x43 | PAR2 | 5NDD | apelin receptor | 5VBL |
| TM4 | 144 | W | 4.44x44 | PAR2 | 5NDD | BLT1 receptor | 5X33 |
| TM4 | 145 | V | 4.45x45 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM4 | 146 | C | 4.46x46 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM4 | 147 | G | 4.47x47 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM4 | 148 | L | 4.48x48 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM4 | 149 | L | 4.49x49 | PAR2 | 5NDD | DP2 receptor | 6D27 |
| TM4 | 150 | W | 4.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 151 | T | 4.51x51 | PAR2 | 5NDD | CB1 receptor | 5TGZ |
| TM4 | 152 | L | 4.52x52 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 153 | C | 4.53x53 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM4 | 154 | L | 4.54x54 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 155 | L | 4.55x55 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 156 | M | 4.56x56 | PAR2 | 5NDD | LPA1 receptor | 4Z35 |
| TM4 | 157 | N | 4.57x57 | P2Y1 receptor | 4XNW | - | - |
| TM4 | 158 | G | 4.58x58 | P2Y1 receptor | 4XNW | FFA1 receptor | 5TZY |
| TM4 | 159 | L | 4.59x59 | P2Y1 receptor | 4XNW | succinate receptor | 6RNK |
| TM4 | 160 | T | 4.60x60 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM4 | 161 | S | 4.61x61 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM4 | 162 | S | 4.62x62 | PAR2 | 5NDD | - | - |
| TM4 | 163 | F | 4.63x63 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM4 | 164 | C | 4.64x64 | C5a1 receptor | 5O9H | - | - |
| ECL2 | 165 | S | - | - | - | - | |
| ECL2 | 166 | K | - | - | - | - | |
| ECL2 | 167 | F | - | - | - | - | |
| ECL2 | 168 | L | - | - | - | - | |
| ECL2 | 169 | K | - | - | - | - | |
| ECL2 | 170 | F | - | - | - | - | |
| ECL2 | 171 | N | - | - | - | - | |
| ECL2 | 172 | E | - | - | - | - | |
| TM5 | 173 | D | 5.31x32 | PAR2 | 5NDD | C5a1 receptor | 6C1R |
| TM5 | 174 | R | 5.32x33 | PAR2 | 5NDD | - | - |
| TM5 | 175 | C | 5.33x34 | PAR2 | 5NDD | - | - |
| TM5 | 176 | F | 5.34x35 | PAR2 | 5NDD | - | - |
| TM5 | 177 | R | 5.35x36 | PAR2 | 5NDD | CXCR2 | 6LFO |
| TM5 | 178 | V | 5.36x37 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM5 | 179 | D | 5.37x38 | PAR2 | 5NDD | 5-HT2B receptor | 4IB4 |
| TM5 | 180 | M | 5.38x39 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 181 | V | 5.39x40 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM5 | 182 | Q | 5.40x41 | PAR2 | 5NDD | NTS1 receptor | 4BUO |
| TM5 | 183 | A | 5.41x42 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM5 | 184 | A | 5.42x43 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 185 | L | 5.43x44 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM5 | 186 | I | 5.44x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 187 | M | 5.45x46 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM5 | 188 | G | 5.46x461 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM5 | 189 | V | 5.47x47 | PAR2 | 5NDD | CB1 receptor | 5TGZ |
| TM5 | 190 | L | 5.48x48 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 191 | T | 5.49x49 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM5 | 192 | P | 5.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 193 | V | 5.51x51 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM5 | 194 | M | 5.52x52 | PAR2 | 5NDD | CCR6 | 6WWZ |
| TM5 | 195 | T | 5.53x53 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 196 | L | 5.54x54 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 197 | S | 5.55x55 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 198 | S | 5.56x56 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 199 | L | 5.57x57 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM5 | 200 | T | 5.58x58 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM5 | 201 | L | 5.59x59 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 202 | F | 5.60x60 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM5 | 203 | V | 5.61x61 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM5 | 204 | W | 5.62x62 | PAR2 | 5NDD | AT1 receptor | 6OS2 |
| TM5 | 205 | V | 5.63x63 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM5 | 206 | R | 5.64x64 | PAR2 | 5NDD | C5a1 receptor | 5O9H |
| TM5 | 207 | R | 5.65x65 | PAR2 | 5NDD | - | - |
| TM5 | 208 | S | 5.66x66 | C5a1 receptor | 5O9H | PAR1 | 3VW7 |
| TM5 | 209 | S | 5.67x67 | C5a1 receptor | 5O9H | C5a1 receptor | 5O9H |
| TM5 | 210 | Q | 5.68x68 | C5a1 receptor | 5O9H | β2-adrenoceptor | 6OBA |
| ICL3 | 211 | Q | - | - | - | - | |
| ICL3 | 212 | W | - | - | - | - | |
| ICL3 | 213 | R | - | - | - | - | |
| TM6 | 214 | R | 6.28x28 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM6 | 215 | Q | 6.29x29 | PAR2 | 5NDD | CXCR2 | 6LFO |
| TM6 | 216 | P | 6.30x30 | PAR2 | 5NDD | - | - |
| TM6 | 217 | T | 6.31x31 | PAR2 | 5NDD | C5a1 receptor | 6C1R |
| TM6 | 218 | R | 6.32x32 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM6 | 219 | L | 6.33x33 | PAR2 | 5NDD | apelin receptor | 5VBL |
| TM6 | 220 | F | 6.34x34 | PAR2 | 5NDD | AT1 receptor | 4ZUD |
| TM6 | 221 | V | 6.35x35 | PAR2 | 5NDD | MT1 receptor | 6ME2 |
| TM6 | 222 | V | 6.36x36 | PAR2 | 5NDD | P2Y12 receptor | 4PXZ |
| TM6 | 223 | V | 6.37x37 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM6 | 224 | L | 6.38x38 | PAR2 | 5NDD | κ receptor | 6B73 |
| TM6 | 225 | A | 6.39x39 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM6 | 226 | S | 6.40x40 | PAR2 | 5NDD | - | - |
| TM6 | 227 | V | 6.41x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 228 | L | 6.42x42 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM6 | 229 | V | 6.43x43 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM6 | 230 | F | 6.44x44 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM6 | 231 | L | 6.45x45 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM6 | 232 | I | 6.46x46 | C5a1 receptor | 5O9H | C5a1 receptor | 5O9H |
| TM6 | 233 | C | 6.47x47 | C5a1 receptor | 5O9H | PAR2 | 5NDD |
| TM6 | 234 | S | 6.48x48 | PAR2 | 5NDD | EP4 receptor | 5YWY |
| TM6 | 235 | L | 6.49x49 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM6 | 236 | P | 6.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 237 | L | 6.51x51 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM6 | 238 | S | 6.52x52 | PAR2 | 5NDD | OX1 receptor | 6TO7 |
| TM6 | 239 | I | 6.53x53 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM6 | 240 | Y | 6.54x54 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM6 | 241 | W | 6.55x55 | PAR2 | 5NDD | - | - |
| TM6 | 242 | F | 6.56x56 | PAR2 | 5NDD | AT1 receptor | 4ZUD |
| TM6 | 243 | V | 6.57x57 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 244 | L | 6.58x58 | PAR2 | 5NDD | 5-HT2B receptor | 4IB4 |
| TM6 | 245 | Y | 6.59x59 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 246 | W | 6.60x60 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM6 | 247 | L | 6.61x61 | PAR2 | 5NDD | PAR2 | 5NDD |
| ECL3 | 248 | S | - | - | - | - | |
| ECL3 | 249 | L | A2A receptor | 3VG9 | - | - | |
| ECL3 | 250 | P | A2A receptor | 3VG9 | - | - | |
| ECL3 | 251 | P | A2A receptor | 3VG9 | - | - | |
| ECL3 | 252 | E | A2A receptor | 3VG9 | - | - | |
| ECL3 | 253 | M | - | - | - | - | |
| TM7 | 254 | Q | 7.31x30 | PAR2 | 5NDD | μ receptor | 5C1M |
| TM7 | 255 | V | 7.32x31 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM7 | 256 | L | 7.33x32 | PAR2 | 5NDD | AT2 receptor | 6JOD |
| TM7 | 257 | C | 7.34x33 | PAR2 | 5NDD | OX1 receptor | 4ZJ8 |
| TM7 | 258 | F | 7.35x34 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM7 | 259 | S | 7.36x35 | PAR2 | 5NDD | C5a1 receptor | 5O9H |
| TM7 | 260 | L | 7.37x36 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM7 | 261 | S | 7.38x37 | PAR2 | 5NDD | OX1 receptor | 6TO7 |
| TM7 | 262 | R | 7.39x38 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM7 | 263 | L | 7.40x39 | PAR2 | 5NDD | AT2 receptor | 6JOD |
| TM7 | 264 | S | 7.41x40 | PAR2 | 5NDD | - | - |
| TM7 | 265 | S | 7.42x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 266 | S | 7.43x42 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM7 | 267 | V | 7.44x43 | PAR2 | 5NDD | 5-HT2B receptor | 4IB4 |
| TM7 | 268 | S | 7.45x45 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM7 | 269 | S | 7.46x46 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 270 | S | 7.47x47 | PAR2 | 5NDD | κ receptor | 6B73 |
| TM7 | 271 | A | 7.48x48 | PAR2 | 5NDD | DP2 receptor | 6D27 |
| TM7 | 272 | N | 7.49x49 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM7 | 273 | P | 7.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 274 | V | 7.51x51 | PAR2 | 5NDD | PAF receptor | 5ZKQ |
| TM7 | 275 | I | 7.52x52 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM7 | 276 | Y | 7.53x53 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 277 | F | 7.54x54 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM7 | 278 | L | 7.55x55 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM7 | 279 | V | 7.56x56 | PAR2 | 5NDD | PAR2 | 5NDD |
| H8 | 280 | G | 8.47x47 | PAR2 | 5NDD | CCR6 | 6WWZ |
| H8 | 281 | S | 8.48x48 | PAR2 | 5NDD | GPR52 | 6LI1 |
| H8 | 282 | R | 8.49x49 | PAR2 | 5NDD | apelin receptor | 5VBL |
| H8 | 283 | R | 8.50x50 | PAR2 | 5NDD | - | - |
| H8 | 284 | S | 8.51x51 | PAR2 | 5NDD | LPA1 receptor | 4Z35 |
| H8 | 285 | H | 8.52x52 | PAR2 | 5NDD | CXCR2 | 6LFL |
| H8 | 286 | R | 8.53x53 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| H8 | 287 | L | 8.54x54 | PAR2 | 5NDD | succinate receptor | 6RNK |
| H8 | 288 | P | 8.55x55 | PAR2 | 5NDD | - | - |
| H8 | 289 | T | 8.56x56 | PAR2 | 5NDD | M3 receptor | 5ZHP |
| H8 | 290 | R | 8.57x57 | PAR2 | 5NDD | - | - |
| H8 | 291 | S | 8.58x58 | PAR2 | 5NDD | GPR52 | 6LI1 |
| H8 | 292 | L | 8.59x59 | CCR6 | 6WWZ | apelin receptor | 5VBL |
| H8 | 293 | G | 8.60x60 | CCR6 | 6WWZ | - | - |
| H8 | 294 | T | 8.61x61 | CCR6 | 6WWZ | - | - |
| H8 | 295 | V | 8.62x62 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| C-term | 296 | L | - | - | - | - | |
| C-term | 297 | Q | - | - | - | - | |
| C-term | 298 | Q | - | - | - | - | |
| C-term | 299 | A | - | - | - | - | |
| C-term | 300 | L | - | - | - | - |