Y4 receptor homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Intermediate
VERSION
2021-06-10
MODEL
TEMPLATES
5NDD (PAR2)
5ZBH (Y1 receptor)
5ZBQ (Y1 receptor)
5TZY (FFA1 receptor)
7MBX (CCK1 receptor)
7DDZ (Y2 receptor)
None
5ZBH (Y1 receptor)
5ZBQ (Y1 receptor)
5TZY (FFA1 receptor)
7MBX (CCK1 receptor)
7DDZ (Y2 receptor)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 75.9 | 16.7 | 7.4 |
| Side-chains | 19.6 | 62.1 | 18.3 |
Number of backbone templates: 6
Number of rotamer templates: 46
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 32 | E | - | PAR2 | 5NDD | PAR2 | 5NDD |
| N-term | 33 | H | - | PAR2 | 5NDD | PAR2 | 5NDD |
| N-term | 34 | C | - | PAR2 | 5NDD | PAR2 | 5NDD |
| N-term | 35 | Q | - | PAR2 | 5NDD | PAR2 | 5NDD |
| N-term | 36 | D | - | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 37 | S | 1.28x28 | PAR2 | 5NDD | 5-HT1B receptor | 4IAQ |
| TM1 | 38 | V | 1.29x29 | PAR2 | 5NDD | - | - |
| TM1 | 39 | D | 1.30x30 | PAR2 | 5NDD | - | - |
| TM1 | 40 | V | 1.31x31 | PAR2 | 5NDD | Y2 receptor | 7DDZ |
| TM1 | 41 | M | 1.32x32 | PAR2 | 5NDD | M4 receptor | 6KP6 |
| TM1 | 42 | V | 1.33x33 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 43 | F | 1.34x34 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 44 | I | 1.35x35 | PAR2 | 5NDD | κ receptor | 4DJH |
| TM1 | 45 | V | 1.36x36 | PAR2 | 5NDD | NOP receptor | 5DHG |
| TM1 | 46 | T | 1.37x37 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM1 | 47 | S | 1.38x38 | PAR2 | 5NDD | D3 receptor | 7CMV |
| TM1 | 48 | Y | 1.39x39 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 49 | S | 1.40x40 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM1 | 50 | I | 1.41x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 51 | E | 1.42x42 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM1 | 52 | T | 1.43x43 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM1 | 53 | V | 1.44x44 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 54 | V | 1.45x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 55 | G | 1.46x46 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM1 | 56 | V | 1.47x47 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM1 | 57 | L | 1.48x48 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM1 | 58 | G | 1.49x49 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM1 | 59 | N | 1.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 60 | L | 1.51x51 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM1 | 61 | C | 1.52x52 | PAR2 | 5NDD | 5-HT1A receptor | 7E2X |
| TM1 | 62 | L | 1.53x53 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM1 | 63 | M | 1.54x54 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM1 | 64 | C | 1.55x55 | PAR2 | 5NDD | CB1 receptor | 5TGZ |
| TM1 | 65 | V | 1.56x56 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 66 | T | 1.57x57 | PAR2 | 5NDD | Rhodopsin | 1U19 |
| TM1 | 67 | V | 1.58x58 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM1 | 68 | R | 1.59x59 | PAR2 | 5NDD | OX1 receptor | 6TO7 |
| TM1 | 69 | Q | 1.60x60 | PAR2 | 5NDD | CXCR4 | 3ODU |
| ICL1 | 70 | K | 12.48x48 | - | - | - | - |
| ICL1 | 71 | E | 12.49x49 | Y1 receptor | 5ZBH | Y1 receptor | 5ZBH |
| ICL1 | 72 | K | 12.50x50 | Y1 receptor | 5ZBH | - | - |
| ICL1 | 73 | A | 12.51x51 | - | - | - | - |
| TM2 | 74 | N | 2.37x37 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM2 | 75 | V | 2.38x38 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM2 | 76 | T | 2.39x39 | PAR2 | 5NDD | 5-HT2B receptor | 5TVN |
| TM2 | 77 | N | 2.40x40 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM2 | 78 | L | 2.41x41 | PAR2 | 5NDD | OX2 receptor | 6TPN |
| TM2 | 79 | L | 2.42x42 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM2 | 80 | I | 2.43x43 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM2 | 81 | A | 2.44x44 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 82 | N | 2.45x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 83 | L | 2.46x46 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 84 | A | 2.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 85 | F | 2.48x48 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM2 | 86 | S | 2.49x49 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM2 | 87 | D | 2.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 88 | F | 2.51x51 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM2 | 89 | L | 2.52x52 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 90 | M | 2.53x53 | PAR2 | 5NDD | P2Y12 receptor | 4NTJ |
| TM2 | 91 | C | 2.54x54 | PAR2 | 5NDD | CCK1 receptor | 7MBX |
| TM2 | 92 | L | 2.55x55 | Y1 receptor | 5ZBH | P2Y1 receptor | 4XNW |
| TM2 | 93 | L | 2.56x551 | Y1 receptor | 5ZBH | Y2 receptor | 7DDZ |
| TM2 | 94 | C | 2.57x56 | Y1 receptor | 5ZBH | Y1 receptor | 5ZBH |
| TM2 | 95 | Q | 2.58x57 | PAR2 | 5NDD | - | - |
| TM2 | 96 | P | 2.59x58 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 97 | L | 2.60x59 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 98 | T | 2.61x60 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM2 | 99 | A | 2.62x61 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM2 | 100 | V | 2.63x62 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM2 | 101 | Y | 2.64x63 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 102 | T | 2.65x64 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM2 | 103 | I | 2.66x65 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 104 | M | 2.67x66 | PAR2 | 5NDD | Y1 receptor | 5ZBQ |
| TM2 | 105 | D | 2.68x67 | Y1 receptor | 5ZBQ | Y1 receptor | 5ZBQ |
| ECL1 | 106 | Y | 23.49x49 | - | - | - | - |
| ECL1 | 107 | W | 23.50x50 | Y1 receptor | 5ZBQ | Y1 receptor | 5ZBQ |
| ECL1 | 108 | I | 23.51x51 | Y1 receptor | 5ZBQ | PAR2 | 5NDD |
| ECL1 | 109 | F | 23.52x52 | - | - | - | - |
| TM3 | 110 | G | 3.21x21 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 111 | E | 3.22x22 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 112 | T | 3.23x23 | PAR2 | 5NDD | Rhodopsin | 1U19 |
| TM3 | 113 | L | 3.24x24 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 114 | C | 3.25x25 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 115 | K | 3.26x26 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM3 | 116 | M | 3.27x27 | PAR2 | 5NDD | A1 receptor | 5UEN |
| TM3 | 117 | S | 3.28x28 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM3 | 118 | A | 3.29x29 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM3 | 119 | F | 3.30x30 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM3 | 120 | I | 3.31x31 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM3 | 121 | Q | 3.32x32 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM3 | 122 | C | 3.33x33 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM3 | 123 | M | 3.34x34 | PAR2 | 5NDD | D1 receptor | 7JVQ |
| TM3 | 124 | S | 3.35x35 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM3 | 125 | V | 3.36x36 | PAR2 | 5NDD | Y2 receptor | 7DDZ |
| TM3 | 126 | T | 3.37x37 | PAR2 | 5NDD | 5-HT2B receptor | 5TVN |
| TM3 | 127 | V | 3.38x38 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM3 | 128 | S | 3.39x39 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 129 | I | 3.40x40 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 130 | L | 3.41x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 131 | S | 3.42x42 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM3 | 132 | L | 3.43x43 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 133 | V | 3.44x44 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM3 | 134 | L | 3.45x45 | PAR2 | 5NDD | P2Y12 receptor | 4NTJ |
| TM3 | 135 | V | 3.46x46 | PAR2 | 5NDD | NK1 receptor | 6HLP |
| TM3 | 136 | A | 3.47x47 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM3 | 137 | L | 3.48x48 | PAR2 | 5NDD | Y2 receptor | 7DDZ |
| TM3 | 138 | E | 3.49x49 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM3 | 139 | R | 3.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 140 | H | 3.51x51 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM3 | 141 | Q | 3.52x52 | PAR2 | 5NDD | P2Y12 receptor | 4NTJ |
| TM3 | 142 | L | 3.53x53 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM3 | 143 | I | 3.54x54 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 144 | I | 3.55x55 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM3 | 145 | N | 3.56x56 | PAR2 | 5NDD | PAR2 | 5NDD |
| ICL2 | 146 | P | - | - | - | - | - |
| ICL2 | 147 | T | - | Y1 receptor | 5ZBH | - | - |
| ICL2 | 148 | G | - | Y1 receptor | 5ZBH | Y1 receptor | 5ZBH |
| ICL2 | 149 | W | - | Y1 receptor | 5ZBH | Y1 receptor | 5ZBH |
| ICL2 | 150 | K | - | Y1 receptor | 5ZBH | - | - |
| ICL2 | 151 | P | - | - | - | - | - |
| TM4 | 152 | S | 4.38x38 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM4 | 153 | I | 4.39x39 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM4 | 154 | S | 4.40x40 | PAR2 | 5NDD | CCK1 receptor | 7MBX |
| TM4 | 155 | Q | 4.41x41 | PAR2 | 5NDD | AT2 receptor | 5UNG |
| TM4 | 156 | A | 4.42x42 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 157 | Y | 4.43x43 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM4 | 158 | L | 4.44x44 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM4 | 159 | G | 4.45x45 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM4 | 160 | I | 4.46x46 | PAR2 | 5NDD | 5-HT2B receptor | 5TVN |
| TM4 | 161 | V | 4.47x47 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM4 | 162 | L | 4.48x48 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM4 | 163 | I | 4.49x49 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 164 | W | 4.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 165 | V | 4.51x51 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM4 | 166 | I | 4.52x52 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM4 | 167 | A | 4.53x53 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM4 | 168 | C | 4.54x54 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM4 | 169 | V | 4.55x55 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM4 | 170 | L | 4.56x56 | PAR2 | 5NDD | P2Y12 receptor | 4NTJ |
| TM4 | 171 | S | 4.57x57 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM4 | 172 | L | 4.58x59 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM4 | 173 | P | 4.59x60 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 174 | F | 4.60x61 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM4 | 175 | L | 4.61x62 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM4 | 176 | A | 4.62x63 | PAR2 | 5NDD | OX1 receptor | 6TO7 |
| TM4 | 177 | N | 4.63x64 | Y1 receptor | 5ZBQ | - | - |
| TM4 | 178 | S | 4.64x65 | Y1 receptor | 5ZBQ | CCK1 receptor | 7MBX |
| ECL2 | 179 | I | - | - | - | - | - |
| ECL2 | 180 | L | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 181 | E | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 182 | N | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 183 | V | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 184 | F | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 185 | H | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 186 | K | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 187 | N | - | FFA1 receptor | 5TZY | FFA1 receptor | 5TZY |
| ECL2 | 188 | H | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 189 | S | - | FFA1 receptor | 5TZY | FFA1 receptor | 5TZY |
| ECL2 | 190 | K | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 191 | A | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 192 | L | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 193 | E | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 194 | F | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 195 | L | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 196 | A | - | - | - | - | - |
| ECL2 | 197 | D | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 198 | K | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 199 | V | - | FFA1 receptor | 5TZY | - | - |
| ECL2 | 200 | V | - | - | - | - | - |
| ECL2 | 201 | C | 45.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| ECL2 | 202 | T | 45.51x51 | PAR2 | 5NDD | FPR2/ALX | 6OMM |
| ECL2 | 203 | E | 45.52x52 | PAR2 | 5NDD | PAF receptor | 5ZKQ |
| ECL2 | 204 | S | - | - | - | - | - |
| ECL2 | 205 | W | - | Y1 receptor | 5ZBQ | - | - |
| ECL2 | 206 | P | - | - | - | - | - |
| TM5 | 207 | L | 5.31x32 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 208 | A | 5.32x33 | PAR2 | 5NDD | AT2 receptor | 5UNG |
| TM5 | 209 | H | 5.33x34 | PAR2 | 5NDD | - | - |
| TM5 | 210 | H | 5.34x35 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM5 | 211 | R | 5.35x36 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM5 | 212 | T | 5.36x37 | PAR2 | 5NDD | Y2 receptor | 7DDZ |
| TM5 | 213 | I | 5.37x38 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM5 | 214 | Y | 5.38x39 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 215 | T | 5.39x40 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM5 | 216 | T | 5.40x41 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM5 | 217 | F | 5.41x42 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM5 | 218 | L | 5.42x43 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 219 | L | 5.43x44 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 220 | L | 5.44x45 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM5 | 221 | F | 5.45x46 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM5 | 222 | Q | 5.46x461 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM5 | 223 | Y | 5.47x47 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM5 | 224 | C | 5.48x48 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM5 | 225 | L | 5.49x49 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 226 | P | 5.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 227 | L | 5.51x51 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM5 | 228 | G | 5.52x52 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM5 | 229 | F | 5.53x53 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM5 | 230 | I | 5.54x54 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM5 | 231 | L | 5.55x55 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM5 | 232 | V | 5.56x56 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM5 | 233 | C | 5.57x57 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM5 | 234 | Y | 5.58x58 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 235 | A | 5.59x59 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM5 | 236 | R | 5.60x60 | PAR2 | 5NDD | Y2 receptor | 7DDZ |
| TM5 | 237 | I | 5.61x61 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM5 | 238 | Y | 5.62x62 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM5 | 239 | R | 5.63x63 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 240 | R | 5.64x64 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM5 | 241 | L | 5.65x65 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 242 | Q | 5.66x66 | CCK1 receptor | 7MBX | 5-HT2B receptor | 5TVN |
| TM5 | 243 | R | 5.67x67 | CCK1 receptor | 7MBX | GPR52 | 6LI1 |
| TM5 | 244 | Q | 5.68x68 | CCK1 receptor | 7MBX | GPR52 | 6LI2 |
| TM5 | 245 | G | 5.69x69 | CCK1 receptor | 7MBX | FPR2/ALX | 6OMM |
| TM5 | 246 | R | 5.70x70 | CCK1 receptor | 7MBX | 5-HT1A receptor | 7E2X |
| TM5 | 247 | V | 5.71x71 | CCK1 receptor | 7MBX | - | - |
| TM5 | 248 | F | 5.72x72 | CCK1 receptor | 7MBX | - | - |
| ICL3 | 249 | H | - | - | - | - | - |
| ICL3 | 250 | K | - | - | - | - | - |
| ICL3 | 251 | G | - | - | - | - | - |
| ICL3 | 252 | T | - | - | - | - | - |
| ICL3 | 253 | Y | - | - | - | - | - |
| TM6 | 254 | S | 6.24x24 | Y2 receptor | 7DDZ | - | - |
| TM6 | 255 | L | 6.25x25 | Y2 receptor | 7DDZ | D2 receptor | 6VMS |
| TM6 | 256 | R | 6.26x26 | Y2 receptor | 7DDZ | ghrelin receptor | 6KO5 |
| TM6 | 257 | A | 6.27x27 | PAR2 | 5NDD | β1-adrenoceptor | 7BVQ |
| TM6 | 258 | G | 6.28x28 | PAR2 | 5NDD | A1 receptor | 6D9H |
| TM6 | 259 | H | 6.29x29 | PAR2 | 5NDD | US28 | 5WB1 |
| TM6 | 260 | M | 6.30x30 | PAR2 | 5NDD | LPA1 receptor | 4Z35 |
| TM6 | 261 | K | 6.31x31 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM6 | 262 | Q | 6.32x32 | PAR2 | 5NDD | ghrelin receptor | 6KO5 |
| TM6 | 263 | V | 6.33x33 | PAR2 | 5NDD | CCK1 receptor | 7MBX |
| TM6 | 264 | N | 6.34x34 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM6 | 265 | V | 6.35x35 | PAR2 | 5NDD | MT1 receptor | 6ME2 |
| TM6 | 266 | V | 6.36x36 | PAR2 | 5NDD | 5-HT2B receptor | 5TVN |
| TM6 | 267 | L | 6.37x37 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 268 | V | 6.38x38 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM6 | 269 | V | 6.39x39 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 270 | M | 6.40x40 | PAR2 | 5NDD | Rhodopsin | 1U19 |
| TM6 | 271 | V | 6.41x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 272 | V | 6.42x42 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM6 | 273 | A | 6.43x43 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 274 | F | 6.44x44 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM6 | 275 | A | 6.45x45 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM6 | 276 | V | 6.46x46 | Y1 receptor | 5ZBH | Y1 receptor | 5ZBH |
| TM6 | 277 | L | 6.47x47 | Y1 receptor | 5ZBH | succinate receptor | 6RNK |
| TM6 | 278 | W | 6.48x48 | PAR2 | 5NDD | 5-HT2B receptor | 5TVN |
| TM6 | 279 | L | 6.49x49 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM6 | 280 | P | 6.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 281 | L | 6.51x51 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM6 | 282 | H | 6.52x52 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM6 | 283 | V | 6.53x53 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM6 | 284 | F | 6.54x54 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM6 | 285 | N | 6.55x55 | PAR2 | 5NDD | 5-HT2B receptor | 5TVN |
| TM6 | 286 | S | 6.56x56 | PAR2 | 5NDD | CXCR4 | 3ODU |
| TM6 | 287 | L | 6.57x57 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM6 | 288 | E | 6.58x58 | PAR2 | 5NDD | GPR52 | 6LI0 |
| TM6 | 289 | D | 6.59x59 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM6 | 290 | W | 6.60x60 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM6 | 291 | H | 6.61x61 | PAR2 | 5NDD | Rhodopsin | 1U19 |
| ECL3 | 292 | H | - | - | - | - | - |
| ECL3 | 293 | E | - | Y1 receptor | 5ZBH | - | - |
| ECL3 | 294 | A | - | Y1 receptor | 5ZBH | - | - |
| ECL3 | 295 | I | - | Y1 receptor | 5ZBH | Y1 receptor | 5ZBH |
| ECL3 | 296 | P | - | - | - | - | - |
| TM7 | 297 | I | 7.28x27 | Y1 receptor | 5ZBH | - | - |
| TM7 | 298 | C | 7.29x28 | Y1 receptor | 5ZBH | Y1 receptor | 5ZBH |
| TM7 | 299 | H | 7.30x29 | Y1 receptor | 5ZBH | CXCR2 | 6LFL |
| TM7 | 300 | G | 7.31x30 | PAR2 | 5NDD | - | - |
| TM7 | 301 | N | 7.32x31 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM7 | 302 | L | 7.33x32 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM7 | 303 | I | 7.34x33 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM7 | 304 | F | 7.35x34 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM7 | 305 | L | 7.36x35 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM7 | 306 | V | 7.37x36 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 307 | C | 7.38x37 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM7 | 308 | H | 7.39x38 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM7 | 309 | L | 7.40x39 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM7 | 310 | L | 7.41x40 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 311 | A | 7.42x41 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM7 | 312 | M | 7.43x42 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM7 | 313 | A | 7.44x43 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM7 | 314 | S | 7.45x45 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM7 | 315 | T | 7.46x46 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM7 | 316 | C | 7.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 317 | V | 7.48x48 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM7 | 318 | N | 7.49x49 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM7 | 319 | P | 7.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 320 | F | 7.51x51 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 321 | I | 7.52x52 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM7 | 322 | Y | 7.53x53 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 323 | G | 7.54x54 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM7 | 324 | F | 7.55x55 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 325 | L | 7.56x56 | PAR2 | 5NDD | P2Y12 receptor | 4NTJ |
| H8 | 326 | N | 8.47x47 | PAR2 | 5NDD | 5-HT2B receptor | 5TVN |
| H8 | 327 | T | 8.48x48 | PAR2 | 5NDD | US28 | 5WB1 |
| H8 | 328 | N | 8.49x49 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| H8 | 329 | F | 8.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| H8 | 330 | K | 8.51x51 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| H8 | 331 | K | 8.52x52 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| H8 | 332 | E | 8.53x53 | PAR2 | 5NDD | OX2 receptor | 5WQC |
| H8 | 333 | I | 8.54x54 | PAR2 | 5NDD | - | - |
| H8 | 334 | K | 8.55x55 | PAR2 | 5NDD | PAR2 | 5NDD |
| H8 | 335 | A | 8.56x56 | PAR2 | 5NDD | OX2 receptor | 5WQC |
| H8 | 336 | L | 8.57x57 | PAR2 | 5NDD | GPR52 | 6LI1 |
| H8 | 337 | V | 8.58x58 | PAR2 | 5NDD | 5-HT1D receptor | 7E32 |
| C-term | 338 | L | - | - | - | - | - |
| C-term | 339 | T | - | - | - | - | - |
| C-term | 340 | C | - | - | - | - | - |
| C-term | 341 | Q | - | - | - | - | - |
| C-term | 342 | Q | - | - | - | - | - |