P2RY8 homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Intermediate
VERSION
2021-01-08
MODEL
TEMPLATES
5NDD (PAR2)
5NDZ (PAR2)
4XNW (P2Y1 receptor)
3VW7 (PAR1)
6LFL (CXCR2)
None
5NDZ (PAR2)
4XNW (P2Y1 receptor)
3VW7 (PAR1)
6LFL (CXCR2)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 86.8 | 5.9 | 7.3 |
| Side-chains | 33.3 | 49.2 | 17.5 |
Number of backbone templates: 5
Number of rotamer templates: 43
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 14 | L | PAR2 | 5NDD | PAR2 | 5NDD | |
| N-term | 15 | Q | PAR2 | 5NDD | PAR2 | 5NDD | |
| N-term | 16 | M | PAR2 | 5NDD | PAR2 | 5NDD | |
| N-term | 17 | L | PAR2 | 5NDD | PAR2 | 5NDD | |
| N-term | 18 | R | PAR2 | 5NDD | PAR2 | 5NDD | |
| TM1 | 19 | N | 1.28x28 | PAR2 | 5NDD | CB1 receptor | 5U09 |
| TM1 | 20 | P | 1.29x29 | PAR2 | 5NDD | Rhodopsin | 1GZM |
| TM1 | 21 | A | 1.30x30 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM1 | 22 | I | 1.31x31 | PAR2 | 5NDD | κ receptor | 6B73 |
| TM1 | 23 | A | 1.32x32 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM1 | 24 | V | 1.33x33 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 25 | A | 1.34x34 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM1 | 26 | L | 1.35x35 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 27 | P | 1.36x36 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 28 | V | 1.37x37 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM1 | 29 | V | 1.38x38 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 30 | Y | 1.39x39 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 31 | S | 1.40x40 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM1 | 32 | L | 1.41x41 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM1 | 33 | V | 1.42x42 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 34 | A | 1.43x43 | PAR2 | 5NDD | A1 receptor | 5UEN |
| TM1 | 35 | A | 1.44x44 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM1 | 36 | V | 1.45x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 37 | S | 1.46x46 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM1 | 38 | I | 1.47x47 | PAR2 | 5NDD | 5-HT2B receptor | 4IB4 |
| TM1 | 39 | P | 1.48x48 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 40 | G | 1.49x49 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM1 | 41 | N | 1.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 42 | L | 1.51x51 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM1 | 43 | F | 1.52x52 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM1 | 44 | S | 1.53x53 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM1 | 45 | L | 1.54x54 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 46 | W | 1.55x55 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 47 | V | 1.56x56 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 48 | L | 1.57x57 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM1 | 49 | C | 1.58x58 | PAR2 | 5NDD | AT2 receptor | 6JOD |
| TM1 | 50 | R | 1.59x59 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM1 | 51 | R | 1.60x60 | PAR2 | 5NDD | PAR2 | 5NDD |
| ICL1 | 52 | M | PAR2 | 5NDD | - | - | |
| ICL1 | 53 | G | PAR2 | 5NDD | - | - | |
| ICL1 | 54 | P | PAR2 | 5NDD | - | - | |
| ICL1 | 55 | R | PAR2 | 5NDD | - | - | |
| TM2 | 56 | S | 2.37x37 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM2 | 57 | P | 2.38x38 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 58 | S | 2.39x39 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM2 | 59 | V | 2.40x40 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 60 | I | 2.41x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 61 | F | 2.42x42 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM2 | 62 | M | 2.43x43 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 63 | I | 2.44x44 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM2 | 64 | N | 2.45x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 65 | L | 2.46x46 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 66 | S | 2.47x47 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM2 | 67 | V | 2.48x48 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM2 | 68 | T | 2.49x49 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM2 | 69 | D | 2.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 70 | L | 2.51x51 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 71 | M | 2.52x52 | PAR2 | 5NDD | - | - |
| TM2 | 72 | L | 2.53x53 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM2 | 73 | A | 2.54x54 | PAR2 | 5NDD | CXCR2 | 6LFL |
| TM2 | 74 | S | 2.55x55 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM2 | 75 | V | 2.56x56 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM2 | 76 | L | 2.57x57 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM2 | 77 | P | 2.58x58 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 78 | F | 2.59x59 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM2 | 79 | Q | 2.60x60 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM2 | 80 | I | 2.61x61 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 81 | Y | 2.62x62 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM2 | 82 | Y | 2.63x63 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 83 | H | 2.64x64 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 84 | C | 2.65x65 | PAR2 | 5NDD | Rhodopsin | 6I9K |
| TM2 | 85 | N | 2.66x66 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| ECL1 | 86 | R | - | - | - | - | |
| ECL1 | 87 | H | PAR2 | 5NDZ | - | - | |
| ECL1 | 88 | H | 23.49x49 | PAR2 | 5NDZ | C5a1 receptor | 5O9H |
| ECL1 | 89 | W | 23.50x50 | PAR2 | 5NDZ | PAR2 | 5NDZ |
| ECL1 | 90 | V | 23.51x51 | PAR2 | 5NDZ | CCR7 | 6QZH |
| ECL1 | 91 | F | 23.52x52 | - | - | - | - |
| TM3 | 92 | G | 3.21x21 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 93 | V | 3.22x22 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM3 | 94 | L | 3.23x23 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM3 | 95 | L | 3.24x24 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 96 | C | 3.25x25 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 97 | N | 3.26x26 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 98 | V | 3.27x27 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 99 | V | 3.28x28 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 100 | T | 3.29x29 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 101 | V | 3.30x30 | PAR2 | 5NDD | P2Y12 receptor | 4NTJ |
| TM3 | 102 | A | 3.31x31 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 103 | F | 3.32x32 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 104 | Y | 3.33x33 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 105 | A | 3.34x34 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 106 | N | 3.35x35 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 107 | M | 3.36x36 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 108 | Y | 3.37x37 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 109 | S | 3.38x38 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM3 | 110 | S | 3.39x39 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 111 | I | 3.40x40 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 112 | L | 3.41x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 113 | T | 3.42x42 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM3 | 114 | M | 3.43x43 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 115 | T | 3.44x44 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 116 | C | 3.45x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 117 | I | 3.46x46 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 118 | S | 3.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 119 | V | 3.48x48 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 120 | E | 3.49x49 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM3 | 121 | R | 3.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 122 | F | 3.51x51 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 123 | L | 3.52x52 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 124 | G | 3.53x53 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM3 | 125 | V | 3.54x54 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 126 | L | 3.55x55 | PAR2 | 5NDD | FPR2/ALX | 6LW5 |
| TM3 | 127 | Y | 3.56x56 | PAR2 | 5NDD | PAR1 | 3VW7 |
| ICL2 | 128 | P | 34.50x50 | - | - | - | - |
| ICL2 | 129 | L | 34.51x51 | P2Y1 receptor | 4XNW | P2Y1 receptor | 4XNW |
| ICL2 | 130 | S | 34.52x52 | P2Y1 receptor | 4XNW | GPR52 | 6LI1 |
| ICL2 | 131 | S | 34.53x53 | P2Y1 receptor | 4XNW | P2Y1 receptor | 4XNW |
| ICL2 | 132 | K | 34.54x54 | P2Y1 receptor | 4XNW | ghrelin receptor | 6KO5 |
| ICL2 | 133 | R | 34.55x55 | P2Y1 receptor | 4XNW | C5a1 receptor | 5O9H |
| ICL2 | 134 | W | 34.56x56 | P2Y1 receptor | 4XNW | CCR9 | 5LWE |
| ICL2 | 135 | R | 34.57x57 | - | - | - | - |
| TM4 | 136 | R | 4.38x38 | PAR2 | 5NDD | CCR9 | 5LWE |
| TM4 | 137 | R | 4.39x39 | PAR2 | 5NDD | PAF receptor | 5ZKQ |
| TM4 | 138 | R | 4.40x40 | PAR2 | 5NDD | CysLT2 receptor | 6RZ8 |
| TM4 | 139 | Y | 4.41x41 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM4 | 140 | A | 4.42x42 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 141 | V | 4.43x43 | PAR2 | 5NDD | CCR5 | 5UIW |
| TM4 | 142 | A | 4.44x44 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM4 | 143 | A | 4.45x45 | PAR2 | 5NDD | apelin receptor | 5VBL |
| TM4 | 144 | C | 4.46x46 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM4 | 145 | A | 4.47x47 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM4 | 146 | G | 4.48x48 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM4 | 147 | T | 4.49x49 | PAR2 | 5NDD | CCR5 | 5UIW |
| TM4 | 148 | W | 4.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 149 | L | 4.51x51 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 150 | L | 4.52x52 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 151 | L | 4.53x53 | PAR2 | 5NDD | - | - |
| TM4 | 152 | L | 4.54x54 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 153 | T | 4.55x55 | PAR2 | 5NDD | D2 receptor | 6CM4 |
| TM4 | 154 | A | 4.56x56 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM4 | 155 | L | 4.57x57 | P2Y1 receptor | 4XNW | FFA1 receptor | 5TZY |
| TM4 | 156 | S | 4.58x58 | P2Y1 receptor | 4XNW | P2Y1 receptor | 4XNW |
| TM4 | 157 | P | 4.59x59 | P2Y1 receptor | 4XNW | P2Y1 receptor | 4XNW |
| TM4 | 158 | L | 4.60x60 | PAR2 | 5NDD | - | - |
| TM4 | 159 | A | 4.61x61 | PAR2 | 5NDD | AT1 receptor | 4ZUD |
| TM4 | 160 | R | 4.62x62 | PAR2 | 5NDD | - | - |
| ECL2 | 161 | T | PAR2 | 5NDD | - | - | |
| ECL2 | 162 | D | PAR2 | 5NDD | - | - | |
| ECL2 | 163 | L | PAR2 | 5NDD | - | - | |
| ECL2 | 164 | T | PAR2 | 5NDD | PAR2 | 5NDD | |
| ECL2 | 165 | Y | PAR2 | 5NDD | - | - | |
| ECL2 | 166 | P | PAR2 | 5NDD | - | - | |
| ECL2 | 167 | V | PAR2 | 5NDD | - | - | |
| ECL2 | 168 | H | PAR2 | 5NDD | - | - | |
| ECL2 | 169 | A | PAR2 | 5NDD | PAR2 | 5NDD | |
| ECL2 | 170 | L | PAR2 | 5NDD | PAR2 | 5NDD | |
| ECL2 | 171 | G | PAR2 | 5NDD | - | - | |
| ECL2 | 172 | I | PAR2 | 5NDD | PAR2 | 5NDD | |
| ECL2 | 173 | I | PAR2 | 5NDD | - | - | |
| ECL2 | 174 | T | PAR2 | 5NDD | PAR2 | 5NDD | |
| ECL2 | 175 | C | 45.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| ECL2 | 176 | F | 45.51x51 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| ECL2 | 177 | D | 45.52x52 | PAR2 | 5NDD | PAR2 | 5NDD |
| ECL2 | 178 | V | - | - | - | - | |
| ECL2 | 179 | L | - | - | - | - | |
| ECL2 | 180 | K | - | - | - | - | |
| ECL2 | 181 | W | - | - | - | - | |
| ECL2 | 182 | T | - | - | - | - | |
| ECL2 | 183 | M | - | - | - | - | |
| ECL2 | 184 | L | - | - | - | - | |
| ECL2 | 185 | P | - | - | - | - | |
| TM5 | 186 | S | 5.31x32 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM5 | 187 | V | 5.32x33 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 188 | A | 5.33x34 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 189 | M | 5.34x35 | PAR2 | 5NDD | FPR2/ALX | 6LW5 |
| TM5 | 190 | W | 5.35x36 | PAR2 | 5NDD | - | - |
| TM5 | 191 | A | 5.36x37 | PAR2 | 5NDD | AT2 receptor | 6JOD |
| TM5 | 192 | V | 5.37x38 | PAR2 | 5NDD | CysLT1 receptor | 6RZ5 |
| TM5 | 193 | F | 5.38x39 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM5 | 194 | L | 5.39x40 | PAR2 | 5NDD | CCR6 | 6WWZ |
| TM5 | 195 | F | 5.40x41 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM5 | 196 | T | 5.41x42 | PAR2 | 5NDD | AT1 receptor | 4ZUD |
| TM5 | 197 | I | 5.42x43 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM5 | 198 | F | 5.43x44 | PAR2 | 5NDD | δ receptor | 4N6H |
| TM5 | 199 | I | 5.44x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 200 | L | 5.45x46 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM5 | 201 | L | 5.46x461 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM5 | 202 | F | 5.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 203 | L | 5.48x48 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 204 | I | 5.49x49 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM5 | 205 | P | 5.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 206 | F | 5.51x51 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 207 | V | 5.52x52 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM5 | 208 | I | 5.53x53 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM5 | 209 | T | 5.54x54 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 210 | V | 5.55x55 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM5 | 211 | A | 5.56x56 | PAR2 | 5NDD | BLT1 receptor | 5X33 |
| TM5 | 212 | C | 5.57x57 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM5 | 213 | Y | 5.58x58 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 214 | T | 5.59x59 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM5 | 215 | A | 5.60x60 | PAR2 | 5NDD | DP2 receptor | 6D27 |
| TM5 | 216 | T | 5.61x61 | PAR2 | 5NDD | 5-HT2B receptor | 4IB4 |
| TM5 | 217 | I | 5.62x62 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 218 | L | 5.63x63 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM5 | 219 | K | 5.64x64 | PAR2 | 5NDD | GPR52 | 6LI1 |
| TM5 | 220 | L | 5.65x65 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 221 | L | 5.66x66 | PAR1 | 3VW7 | CysLT2 receptor | 6RZ6 |
| TM5 | 222 | R | 5.67x67 | PAR1 | 3VW7 | - | - |
| ICL3 | 223 | T | - | - | - | - | |
| ICL3 | 224 | E | - | - | - | - | |
| ICL3 | 225 | E | - | - | - | - | |
| ICL3 | 226 | A | - | - | - | - | |
| ICL3 | 227 | H | - | - | - | - | |
| TM6 | 228 | G | 6.26x27 | PAR2 | 5NDD | CXCR4 | 3ODU |
| TM6 | 229 | R | 6.27x28 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM6 | 230 | E | 6.28x29 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM6 | 231 | Q | 6.29x30 | PAR2 | 5NDD | - | - |
| TM6 | 232 | R | 6.30x31 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 233 | R | 6.31x32 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM6 | 234 | R | 6.32x33 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 235 | A | 6.33x34 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 236 | V | 6.34x35 | PAR2 | 5NDD | MT1 receptor | 6ME2 |
| TM6 | 237 | G | 6.35x36 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM6 | 238 | L | 6.36x37 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 239 | A | 6.37x38 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 240 | A | 6.38x39 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM6 | 241 | V | 6.39x40 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM6 | 242 | V | 6.40x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 243 | L | 6.41x42 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM6 | 244 | L | 6.42x43 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM6 | 245 | A | 6.43x44 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM6 | 246 | F | 6.44x45 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM6 | 247 | V | 6.45x46 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM6 | 248 | T | 6.46x461 | PAR2 | 5NDD | - | - |
| TM6 | 249 | C | 6.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 250 | F | 6.48x48 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 251 | A | 6.49x49 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| TM6 | 252 | P | 6.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 253 | N | 6.51x51 | PAR2 | 5NDD | - | - |
| TM6 | 254 | N | 6.52x52 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 255 | F | 6.53x53 | PAR2 | 5NDD | P2Y12 receptor | 4NTJ |
| TM6 | 256 | V | 6.54x54 | PAR2 | 5NDD | PAF receptor | 5ZKQ |
| TM6 | 257 | L | 6.55x55 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 258 | L | 6.56x56 | PAR2 | 5NDD | PAF receptor | 5ZKQ |
| TM6 | 259 | A | 6.57x57 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM6 | 260 | H | 6.58x58 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 261 | I | 6.59x59 | PAR2 | 5NDD | succinate receptor | 6RNK |
| TM6 | 262 | V | 6.60x60 | PAR2 | 5NDD | FPR2/ALX | 6LW5 |
| TM6 | 263 | S | 6.61x61 | PAR2 | 5NDD | P2Y12 receptor | 4PXZ |
| ECL3 | 264 | R | PAR2 | 5NDD | - | - | |
| ECL3 | 265 | L | PAR2 | 5NDD | - | - | |
| ECL3 | 266 | F | PAR2 | 5NDD | - | - | |
| ECL3 | 267 | Y | PAR2 | 5NDD | - | - | |
| ECL3 | 268 | G | PAR2 | 5NDD | - | - | |
| ECL3 | 269 | K | PAR2 | 5NDD | - | - | |
| ECL3 | 270 | S | PAR2 | 5NDD | - | - | |
| TM7 | 271 | Y | 7.31x30 | PAR2 | 5NDD | NTS1 receptor | 4BUO |
| TM7 | 272 | Y | 7.32x31 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 273 | H | 7.33x32 | PAR2 | 5NDD | H1 receptor | 3RZE |
| TM7 | 274 | V | 7.34x33 | PAR2 | 5NDD | P2Y12 receptor | 4NTJ |
| TM7 | 275 | Y | 7.35x34 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 276 | K | 7.36x35 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM7 | 277 | L | 7.37x36 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM7 | 278 | T | 7.38x37 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM7 | 279 | L | 7.39x38 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 280 | C | 7.40x39 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 281 | L | 7.41x40 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 282 | S | 7.42x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 283 | C | 7.43x42 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM7 | 284 | L | 7.44x43 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 285 | N | 7.45x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 286 | N | 7.46x46 | PAR2 | 5NDD | AT1 receptor | 4ZUD |
| TM7 | 287 | C | 7.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 288 | L | 7.48x48 | PAR2 | 5NDD | PAF receptor | 5ZKQ |
| TM7 | 289 | D | 7.49x49 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 290 | P | 7.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 291 | F | 7.51x51 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 292 | V | 7.52x52 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 293 | Y | 7.53x53 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 294 | Y | 7.54x54 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 295 | F | 7.55x55 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 296 | A | 7.56x56 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| H8 | 297 | S | 8.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| H8 | 298 | R | 8.48x48 | PAR2 | 5NDD | TP receptor | 6IIV |
| H8 | 299 | E | 8.49x49 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| H8 | 300 | F | 8.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| H8 | 301 | Q | 8.51x51 | PAR2 | 5NDD | AT2 receptor | 6JOD |
| H8 | 302 | L | 8.52x52 | PAR2 | 5NDD | GPR52 | 6LI1 |
| H8 | 303 | R | 8.53x53 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| H8 | 304 | L | 8.54x54 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| H8 | 305 | R | 8.55x55 | PAR2 | 5NDD | GPR52 | 6LI1 |
| H8 | 306 | E | 8.56x56 | PAR2 | 5NDD | MC4 receptor | 6W25 |
| H8 | 307 | Y | 8.57x57 | PAR2 | 5NDD | 5-HT2B receptor | 4IB4 |
| H8 | 308 | L | 8.58x58 | PAR2 | 5NDD | PAR2 | 5NDD |
| H8 | 309 | G | 8.59x59 | CXCR2 | 6LFL | ghrelin receptor | 6KO5 |
| H8 | 310 | C | 8.60x60 | CXCR2 | 6LFL | MC4 receptor | 6W25 |
| H8 | 311 | R | 8.61x61 | CXCR2 | 6LFL | - | - |
| C-term | 312 | R | - | - | - | - | |
| C-term | 313 | V | - | - | - | - | |
| C-term | 314 | P | - | - | - | - | |
| C-term | 315 | R | - | - | - | - | |
| C-term | 316 | D | - | - | - | - |