GPCRdb

TRH₁ receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

TRH₁ receptor

SPECIES

Homo sapiens

STATE

Intermediate

VERSION

2021-01-08

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

NGL is a WebGL based 3D viewer powered by MMTF.

MAIN TEMPLATE

5-HT_2B receptor (sequence similarity: 43%) PDB: 4IB4

Align

TEMPLATES

5DHG (NOP receptor)

4IB4 (5-HT_2B receptor)

5WS3 (OX₂ receptor)

5C1M (μ receptor)

5X93 (ET_B receptor)

6KO5 (ghrelin receptor)

3SN6 (β₂-adrenoceptor)

6I9K (Rhodopsin)

None

	Main template (%)	Additional templates (%)	No template - freely modelled (%)
Backbone	73.5	16.5	10.0
Side-chains	18.7	59.0	22.3

Number of backbone templates: 8
Number of rotamer templates: 45

Segment	Seq.num.	AA	GPCRdb#	Backbone	PDB	Rotamer	PDB

N-term	17	R		-	-	-	-
N-term	18	A		-	-	-	-
N-term	19	V		-	-	-	-
N-term	20	V		-	-	-	-
N-term	21	A		-	-	-	-
TM1	22	L	1.29x29	NOP receptor	5DHG	δ receptor	4EJ4
TM1	23	E	1.30x30	NOP receptor	5DHG	-	-
TM1	24	Y	1.31x31	NOP receptor	5DHG	OX₂ receptor	5WS3
TM1	25	Q	1.32x32	5-HT_2B receptor	4IB4	P2Y₁₂ receptor	4NTJ
TM1	26	V	1.33x33	5-HT_2B receptor	4IB4	PAR2	5NDD
TM1	27	V	1.34x34	5-HT_2B receptor	4IB4	CysLT₁ receptor	6RZ4
TM1	28	T	1.35x35	5-HT_2B receptor	4IB4	S1P₁ receptor	3V2Y
TM1	29	I	1.36x36	5-HT_2B receptor	4IB4	OX₂ receptor	5WS3
TM1	30	L	1.37x37	5-HT_2B receptor	4IB4	P2Y₁₂ receptor	4NTJ
TM1	31	L	1.38x38	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	32	V	1.39x39	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM1	33	L	1.40x40	5-HT_2B receptor	4IB4	CysLT₂ receptor	6RZ6
TM1	34	I	1.41x41	NOP receptor	5DHG	LPA₆ receptor	5XSZ
TM1	35	I	1.42x42	NOP receptor	5DHG	CysLT₂ receptor	6RZ6
TM1	36	C	1.43x43	5-HT_2B receptor	4IB4	TP receptor	6IIV
TM1	37	G	1.44x44	5-HT_2B receptor	4IB4	D₄ receptor	5WIV
TM1	38	L	1.45x45	5-HT_2B receptor	4IB4	GPR52	6LI1
TM1	39	G	1.46x46	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM1	40	I	1.47x47	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	41	V	1.48x48	5-HT_2B receptor	4IB4	OX₁ receptor	6TO7
TM1	42	G	1.49x49	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	43	N	1.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	44	I	1.51x51	5-HT_2B receptor	4IB4	PAR1	3VW7
TM1	45	M	1.52x52	5-HT_2B receptor	4IB4	PAR1	3VW7
TM1	46	V	1.53x53	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	47	V	1.54x54	5-HT_2B receptor	4IB4	succinate receptor	6RNK
TM1	48	L	1.55x55	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	49	V	1.56x56	5-HT_2B receptor	4IB4	PAR1	3VW7
TM1	50	V	1.57x57	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM1	51	M	1.58x58	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM1	52	R	1.59x59	5-HT_2B receptor	4IB4	NOP receptor	5DHG
TM1	53	T	1.60x60	5-HT_2B receptor	4IB4	CysLT₁ receptor	6RZ4
ICL1	54	K	12.48x48	-	-	-	-
ICL1	55	H	12.49x49	OX₂ receptor	5WS3	OX₂ receptor	5WS3
ICL1	56	M	12.50x50	OX₂ receptor	5WS3	OX₂ receptor	5WS3
ICL1	57	R	12.51x51	-	-	-	-
TM2	58	T	2.37x37	5-HT_2B receptor	4IB4	CysLT₂ receptor	6RZ6
TM2	59	P	2.38x38	5-HT_2B receptor	4IB4	PAR1	3VW7
TM2	60	T	2.39x39	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	61	N	2.40x40	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	62	C	2.41x41	5-HT_2B receptor	4IB4	A₁ receptor	5UEN
TM2	63	Y	2.42x42	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM2	64	L	2.43x43	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	65	V	2.44x44	5-HT_2B receptor	4IB4	PAF receptor	5ZKQ
TM2	66	S	2.45x45	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	67	L	2.46x46	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	68	A	2.47x47	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	69	V	2.48x48	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	70	A	2.49x49	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	71	D	2.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	72	L	2.51x51	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	73	M	2.52x52	5-HT_2B receptor	4IB4	-	-
TM2	74	V	2.53x53	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM2	75	L	2.54x54	5-HT_2B receptor	4IB4	succinate receptor	6RNK
TM2	76	V	2.55x55	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM2	77	A	2.56x551	5-HT_2B receptor	4IB4	β₂-adrenoceptor	5JQH
TM2	78	A	2.57x56	5-HT_2B receptor	4IB4	NTS₁ receptor	4BUO
TM2	79	G	2.58x57	5-HT_2B receptor	4IB4	TP receptor	6IIV
TM2	80	L	2.59x58	5-HT_2B receptor	4IB4	GPR52	6LI1
TM2	81	P	2.60x59	5-HT_2B receptor	4IB4	Rhodopsin	6I9K
TM2	82	N	2.61x60	5-HT_2B receptor	4IB4	H₁ receptor	3RZE
TM2	83	I	2.62x61	5-HT_2B receptor	4IB4	PAR1	3VW7
TM2	84	T	2.63x62	5-HT_2B receptor	4IB4	NOP receptor	5DHG
TM2	85	D	2.64x63	5-HT_2B receptor	4IB4	NOP receptor	5DHG
TM2	86	S	2.65x64	5-HT_2B receptor	4IB4	Rhodopsin	4ZWJ
TM2	87	I	2.66x65	5-HT_2B receptor	4IB4	PAR2	5NDD
TM2	88	Y	2.67x66	5-HT_2B receptor	4IB4	-	-
ECL1	89	G		-	-	-	-
ECL1	90	S	23.49x49	NOP receptor	5DHG	OX₁ receptor	6TO7
ECL1	91	W	23.50x50	NOP receptor	5DHG	NOP receptor	5DHG
ECL1	92	V	23.51x51	NOP receptor	5DHG	Rhodopsin	6I9K
ECL1	93	Y	23.52x52	-	-	-	-
TM3	94	G	3.21x21	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM3	95	Y	3.22x22	5-HT_2B receptor	4IB4	MT₁ receptor	6ME2
TM3	96	V	3.23x23	5-HT_2B receptor	4IB4	5-HT_2B receptor	4NC3
TM3	97	G	3.24x24	5-HT_2B receptor	4IB4	NTS₁ receptor	4BUO
TM3	98	C	3.25x25	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	99	L	3.26x26	5-HT_2B receptor	4IB4	H₁ receptor	3RZE
TM3	100	C	3.27x27	5-HT_2B receptor	4IB4	-	-
TM3	101	I	3.28x28	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM3	102	T	3.29x29	5-HT_2B receptor	4IB4	PAR1	3VW7
TM3	103	Y	3.30x30	5-HT_2B receptor	4IB4	CysLT₂ receptor	6RZ6
TM3	104	L	3.31x31	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	105	Q	3.32x32	5-HT_2B receptor	4IB4	OX₂ receptor	5WS3
TM3	106	Y	3.33x33	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM3	107	L	3.34x34	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	108	G	3.35x35	5-HT_2B receptor	4IB4	Rhodopsin	4ZWJ
TM3	109	I	3.36x36	5-HT_2B receptor	4IB4	NK₁ receptor	6HLP
TM3	110	N	3.37x37	5-HT_2B receptor	4IB4	M₂ receptor	5ZKC
TM3	111	A	3.38x38	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	112	S	3.39x39	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	113	S	3.40x40	5-HT_2B receptor	4IB4	-	-
TM3	114	C	3.41x41	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM3	115	S	3.42x42	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM3	116	I	3.43x43	5-HT_2B receptor	4IB4	ghrelin receptor	6KO5
TM3	117	T	3.44x44	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM3	118	A	3.45x45	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	119	F	3.46x46	5-HT_2B receptor	4IB4	-	-
TM3	120	T	3.47x47	5-HT_2B receptor	4IB4	P2Y₁₂ receptor	4NTJ
TM3	121	I	3.48x48	5-HT_2B receptor	4IB4	PAR1	3VW7
TM3	122	E	3.49x49	5-HT_2B receptor	4IB4	TP receptor	6IIV
TM3	123	R	3.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	124	Y	3.51x51	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	125	I	3.52x52	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	126	A	3.53x53	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	127	I	3.54x54	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM3	128	C	3.55x55	5-HT_2B receptor	4IB4	NOP receptor	5DHG
TM3	129	H	3.56x56	5-HT_2B receptor	4IB4	CysLT₂ receptor	6RZ6
ICL2	130	P	34.50x50	-	-	-	-
ICL2	131	I	34.51x51	μ receptor	5C1M	α_2A-adrenoceptor	6KUX
ICL2	132	K	34.52x52	μ receptor	5C1M	μ receptor	5C1M
ICL2	133	A	34.53x53	μ receptor	5C1M	μ receptor	5C1M
ICL2	134	Q	34.54x54	μ receptor	5C1M	FFA1 receptor	5TZY
ICL2	135	F	34.55x55	μ receptor	5C1M	-	-
ICL2	136	L	34.56x56	μ receptor	5C1M	LPA₆ receptor	5XSZ
ICL2	137	C	34.57x57	-	-	-	-
TM4	138	T	4.38x38	5-HT_2B receptor	4IB4	CysLT₁ receptor	6RZ4
TM4	139	F	4.39x39	5-HT_2B receptor	4IB4	-	-
TM4	140	S	4.40x40	5-HT_2B receptor	4IB4	NOP receptor	5DHG
TM4	141	R	4.41x41	5-HT_2B receptor	4IB4	PAR1	3VW7
TM4	142	A	4.42x42	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM4	143	K	4.43x43	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM4	144	K	4.44x44	5-HT_2B receptor	4IB4	NTS₁ receptor	4BUO
TM4	145	I	4.45x45	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM4	146	I	4.46x46	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM4	147	I	4.47x47	5-HT_2B receptor	4IB4	GPR52	6LI1
TM4	148	F	4.48x48	5-HT_2B receptor	4IB4	Rhodopsin	6I9K
TM4	149	V	4.49x49	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM4	150	W	4.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM4	151	A	4.51x51	5-HT_2B receptor	4IB4	PAR1	3VW7
TM4	152	F	4.52x52	5-HT_2B receptor	4IB4	CysLT₁ receptor	6RZ4
TM4	153	T	4.53x53	5-HT_2B receptor	4IB4	MT₁ receptor	6ME2
TM4	154	S	4.54x54	5-HT_2B receptor	4IB4	NOP receptor	5DHG
TM4	155	L	4.55x55	5-HT_2B receptor	4IB4	PAR2	5NDD
TM4	156	Y	4.56x56	5-HT_2B receptor	4IB4	-	-
TM4	157	C	4.57x57	NOP receptor	5DHG	CCR9	5LWE
TM4	158	M	4.58x58	NOP receptor	5DHG	-	-
TM4	159	L	4.59x59	NOP receptor	5DHG	MC₄ receptor	6W25
TM4	160	W	4.60x60	5-HT_2B receptor	4IB4	-	-
TM4	161	F	4.61x61	5-HT_2B receptor	4IB4	CysLT₁ receptor	6RZ4
TM4	162	F	4.62x62	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM4	163	L	4.63x63	5-HT_2B receptor	4IB4	PAR1	3VW7
TM4	164	L	4.64x64	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
ECL2	165	D		-	-	-	-
ECL2	166	L		ET_B receptor	5X93	-	-
ECL2	167	N		ET_B receptor	5X93	-	-
ECL2	168	I		ET_B receptor	5X93	-	-
ECL2	169	S		ET_B receptor	5X93	-	-
ECL2	170	T		ET_B receptor	5X93	-	-
ECL2	171	Y		ET_B receptor	5X93	ET_B receptor	5X93
ECL2	172	K		ET_B receptor	5X93	-	-
ECL2	173	D		ET_B receptor	5X93	-	-
ECL2	174	A		ET_B receptor	5X93	-	-
ECL2	175	I		ET_B receptor	5X93	-	-
ECL2	176	V		ET_B receptor	5X93	-	-
ECL2	177	I		ET_B receptor	5X93	-	-
ECL2	178	S		-	-	-	-
ECL2	179	C	45.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
ECL2	180	G	45.51x51	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
ECL2	181	Y	45.52x52	5-HT_2B receptor	4IB4	DP₂ receptor	6D27
ECL2	182	K		-	-	-	-
TM5	183	I	5.30x30	ET_B receptor	5X93	-	-
TM5	184	S	5.31x31	ET_B receptor	5X93	apelin receptor	5VBL
TM5	185	R	5.32x32	ET_B receptor	5X93	-	-
TM5	186	N	5.33x33	ET_B receptor	5X93	DP₂ receptor	6D27
TM5	187	Y	5.34x34	ET_B receptor	5X93	PAR1	3VW7
TM5	188	Y	5.35x35	ET_B receptor	5X93	ET_B receptor	5X93
TM5	189	S	5.36x36	5-HT_2B receptor	4IB4	succinate receptor	6RNK
TM5	190	P	5.37x37	5-HT_2B receptor	4IB4	NOP receptor	5DHG
TM5	191	I	5.38x38	5-HT_2B receptor	4IB4	succinate receptor	6RNK
TM5	192	Y	5.39x39	5-HT_2B receptor	4IB4	PAR2	5NDD
TM5	193	L	5.40x40	5-HT_2B receptor	4IB4	Rhodopsin	6I9K
TM5	194	M	5.41x41	5-HT_2B receptor	4IB4	P2Y₁ receptor	4XNW
TM5	195	D	5.42x42	5-HT_2B receptor	4IB4	-	-
TM5	196	F	5.43x43	5-HT_2B receptor	4IB4	GPR52	6LI1
TM5	197	G	5.44x44	5-HT_2B receptor	4IB4	-	-
TM5	198	V	5.45x45	5-HT_2B receptor	4IB4	PAR1	3VW7
TM5	199	F	5.46x46	ghrelin receptor	6KO5	ghrelin receptor	6KO5
TM5	200	Y	5.47x47	ghrelin receptor	6KO5	OX₂ receptor	5WS3
TM5	201	V	5.48x48	5-HT_2B receptor	4IB4	κ receptor	6B73
TM5	202	V	5.49x49	5-HT_2B receptor	4IB4	PAR1	3VW7
TM5	203	P	5.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM5	204	M	5.51x51	5-HT_2B receptor	4IB4	NTS₁ receptor	4BUO
TM5	205	I	5.52x52	5-HT_2B receptor	4IB4	PAR1	3VW7
TM5	206	L	5.53x53	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM5	207	A	5.54x54	5-HT_2B receptor	4IB4	NTS₁ receptor	4BUO
TM5	208	T	5.55x55	5-HT_2B receptor	4IB4	PAR1	3VW7
TM5	209	V	5.56x56	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM5	210	L	5.57x57	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM5	211	Y	5.58x58	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM5	212	G	5.59x59	5-HT_2B receptor	4IB4	P2Y₁ receptor	4XNW
TM5	213	F	5.60x60	5-HT_2B receptor	4IB4	GPR52	6LI1
TM5	214	I	5.61x61	5-HT_2B receptor	4IB4	PAR1	3VW7
TM5	215	A	5.62x62	5-HT_2B receptor	4IB4	NTS₁ receptor	4BUO
TM5	216	R	5.63x63	5-HT_2B receptor	4IB4	PAR1	3VW7
TM5	217	I	5.64x64	5-HT_2B receptor	4IB4	α_2A-adrenoceptor	6KUX
TM5	218	L	5.65x65	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM5	219	F	5.66x66	5-HT_2B receptor	4IB4	CXCR2	6LFL
TM5	220	L	5.67x67	5-HT_2B receptor	4IB4	α_2C-adrenoceptor	6KUW
TM5	221	N	5.68x68	5-HT_2B receptor	4IB4	-	-
TM5	222	P	5.69x69	5-HT_2B receptor	4IB4	-	-
TM5	223	I	5.70x70	β₂-adrenoceptor	3SN6	-	-
TM5	224	P	5.71x71	β₂-adrenoceptor	3SN6	-	-
TM5	225	S	5.72x72	β₂-adrenoceptor	3SN6	-	-
TM5	226	D	5.73x73	β₂-adrenoceptor	3SN6	β₂-adrenoceptor	3SN6
TM5	227	P	5.74x74	β₂-adrenoceptor	3SN6	-	-
TM5	228	K	5.75x75	β₂-adrenoceptor	3SN6	-	-
TM5	229	E	5.76x76	β₂-adrenoceptor	3SN6	β₂-adrenoceptor	3SN6
ICL3	230	N		-	-	-	-
ICL3	231	S		-	-	-	-
ICL3	232	K		-	-	-	-
ICL3	233	T		-	-	-	-
ICL3	234	W		-	-	-	-
ICL3	250	S		-	-	-	-
ICL3	251	N		-	-	-	-
ICL3	252	R		-	-	-	-
ICL3	253	C		-	-	-	-
ICL3	254	F		-	-	-	-
TM6	255	N	6.24x24	NOP receptor	5DHG	Rhodopsin	6I9K
TM6	256	S	6.25x25	5-HT_2B receptor	4IB4	A_2A receptor	4UHR
TM6	257	T	6.26x26	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	258	V	6.27x27	5-HT_2B receptor	4IB4	NTS₁ receptor	4BUO
TM6	259	S	6.28x28	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	260	S	6.29x29	5-HT_2B receptor	4IB4	PAR1	3VW7
TM6	261	R	6.30x30	5-HT_2B receptor	4IB4	FFA1 receptor	5TZY
TM6	262	K	6.31x31	5-HT_2B receptor	4IB4	PAR1	3VW7
TM6	263	Q	6.32x32	5-HT_2B receptor	4IB4	ghrelin receptor	6KO5
TM6	264	V	6.33x33	5-HT_2B receptor	4IB4	M₂ receptor	5ZKC
TM6	265	T	6.34x34	5-HT_2B receptor	4IB4	NOP receptor	5DHG
TM6	266	K	6.35x35	5-HT_2B receptor	4IB4	OX₁ receptor	6TO7
TM6	267	M	6.36x36	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM6	268	L	6.37x37	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	269	A	6.38x38	5-HT_2B receptor	4IB4	PAR2	5NDD
TM6	270	V	6.39x39	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM6	271	V	6.40x40	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	272	V	6.41x41	5-HT_2B receptor	4IB4	PAR1	3VW7
TM6	273	I	6.42x42	5-HT_2B receptor	4IB4	P2Y₁₂ receptor	4NTJ
TM6	274	L	6.43x43	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	275	F	6.44x44	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	276	A	6.45x45	5-HT_2B receptor	4IB4	TP receptor	6IIV
TM6	277	L	6.46x46	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	278	L	6.47x47	5-HT_2B receptor	4IB4	succinate receptor	6RNK
TM6	279	W	6.48x48	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	280	M	6.49x49	5-HT_2B receptor	4IB4	CysLT₁ receptor	6RZ4
TM6	281	P	6.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM6	282	Y	6.51x51	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM6	283	R	6.52x52	5-HT_2B receptor	4IB4	-	-
TM6	284	T	6.53x53	5-HT_2B receptor	4IB4	CysLT₂ receptor	6RZ6
TM6	285	L	6.54x54	5-HT_2B receptor	4IB4	PAR1	3VW7
TM6	286	V	6.55x55	5-HT_2B receptor	4IB4	NOP receptor	5DHG
TM6	287	V	6.56x56	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM6	288	V	6.57x57	5-HT_2B receptor	4IB4	PAR2	5NDD
TM6	289	N	6.58x58	5-HT_2B receptor	4IB4	P2Y₁ receptor	4XNW
TM6	290	S	6.59x59	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM6	291	F	6.60x60	5-HT_2B receptor	4IB4	PAR2	5NDD
TM6	292	L	6.61x61	5-HT_2B receptor	4IB4	ET_B receptor	5XPR
ECL3	293	S		-	-	-	-
ECL3	294	S		Rhodopsin	6I9K	-	-
ECL3	295	P		Rhodopsin	6I9K	-	-
ECL3	296	F		Rhodopsin	6I9K	-	-
ECL3	297	Q		-	-	-	-
TM7	298	E	7.31x30	5-HT_2B receptor	4IB4	OT receptor	6TPK
TM7	299	N	7.32x31	5-HT_2B receptor	4IB4	succinate receptor	6RNK
TM7	300	W	7.33x32	5-HT_2B receptor	4IB4	A_2A receptor	4UHR
TM7	301	F	7.34x33	5-HT_2B receptor	4IB4	NTS₁ receptor	4BUO
TM7	302	L	7.35x34	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	303	L	7.36x35	5-HT_2B receptor	4IB4	PAR1	3VW7
TM7	304	F	7.37x36	5-HT_2B receptor	4IB4	NOP receptor	5DHG
TM7	305	C	7.38x37	5-HT_2B receptor	4IB4	PAR1	3VW7
TM7	306	R	7.39x38	5-HT_2B receptor	4IB4	succinate receptor	6RNK
TM7	307	I	7.40x39	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM7	308	C	7.41x40	5-HT_2B receptor	4IB4	-	-
TM7	309	I	7.42x41	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
TM7	310	Y	7.43x42	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	311	L	7.44x43	5-HT_2B receptor	4IB4	PAR2	5NDD
TM7	312	N	7.45x45	5-HT_2B receptor	4IB4	LPA₆ receptor	5XSZ
TM7	313	S	7.46x46	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	314	A	7.47x47	5-HT_2B receptor	4IB4	succinate receptor	6RNK
TM7	315	I	7.48x48	5-HT_2B receptor	4IB4	PAR1	3VW7
TM7	316	N	7.49x49	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	317	P	7.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	318	V	7.51x51	5-HT_2B receptor	4IB4	GPR52	6LI1
TM7	319	I	7.52x52	5-HT_2B receptor	4IB4	PAR1	3VW7
TM7	320	Y	7.53x53	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	321	N	7.54x54	5-HT_2B receptor	4IB4	OX₂ receptor	5WS3
TM7	322	L	7.55x55	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
TM7	323	M	7.56x56	5-HT_2B receptor	4IB4	ghrelin receptor	6KO5
H8	324	S	8.47x47	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
H8	325	Q	8.48x48	5-HT_2B receptor	4IB4	MC₄ receptor	6W25
H8	326	K	8.49x49	5-HT_2B receptor	4IB4	OX₂ receptor	5WS3
H8	327	F	8.50x50	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
H8	328	R	8.51x51	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
H8	329	A	8.52x52	5-HT_2B receptor	4IB4	NOP receptor	5DHG
H8	330	A	8.53x53	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
H8	331	F	8.54x54	5-HT_2B receptor	4IB4	5-HT_2B receptor	4IB4
H8	332	R	8.55x55	5-HT_2B receptor	4IB4	GPR52	6LI1
H8	333	K	8.56x56	5-HT_2B receptor	4IB4	CXCR2	6LFL
H8	334	L	8.57x57	5-HT_2B receptor	4IB4	GPR52	6LI1
H8	335	C	8.58x58	5-HT_2B receptor	4IB4	μ receptor	4DKL
H8	336	N	8.59x59	OX₂ receptor	5WS3	A₁ receptor	5UEN
C-term	337	C		-	-	-	-
C-term	338	K		-	-	-	-
C-term	339	Q		-	-	-	-
C-term	340	K		-	-	-	-
C-term	341	P		-	-	-	-

TRH1 receptor homology model