Number of structures, including multiple of same receptor (complex)

Class (Family) Total Class A (Rhodopsin) Class B1 (Secretin) Class B2 (Adhesion) Class C (Glutamate) Class F (Frizzled) Taste 2
Receptors 346 306 19 0 8 13 0
Receptor - ligand complexes 338 299 18 0 8 13 0
Receptor - G protein complexes 10 2 8 0 0 0 0
Active-state receptors* 85 76 8 0 0 1 0


Number of unique receptor complexes

Class (Family) Total Class A (Rhodopsin) Class B1 (Secretin) Class B2 (Adhesion) Class C (Glutamate) Class F (Frizzled) Taste 2
Receptors** 64 54 6 0 2 2 0
Receptor - ligand complexes 220 192 13 0 7 8 0
Receptor - G protein complexes 6 2 4 0 0 0 0
Active-state receptors* 25 20 4 0 0 1 0
*Active state is defined as agonist-bound and opened intracellular TM bundle. **Receptor-orthologues are only counted once.

Specific sets of structures can be downloaded from the structure browser
The latest released structure is from 2019-07-24



By class By ligand type The number of unique receptor with structures available. The number of unique receptors GPCR-ligand complexes. The number of structures available. The number of unique crystallized receptors available. The number of unique GPCR-ligand complexes. The number of structures available.


Structural coverage of GPCR Classes


Class A
(Rhodopsin)




Class B1
(Secretin)

Class B2
(Adhesion)

Class C
(Glutamate)

Class F
(Frizzled)

Taste 2