Number of structures, including multiple of same receptor (complex)

Class (Family) Total Class A (Rhodopsin) Class B1 (Secretin) Class B2 (Adhesion) Class C (Glutamate) Class F (Frizzled) Taste 2
Receptors 321 285 16 0 8 12 0
Receptor - ligand complexes 313 278 15 0 8 12 0
Receptor - G protein complexes 7 2 5 0 0 0 0
Active-state receptors* 74 69 5 0 0 0 0


Number of unique receptor complexes

Class (Family) Total Class A (Rhodopsin) Class B1 (Secretin) Class B2 (Adhesion) Class C (Glutamate) Class F (Frizzled) Taste 2
Receptors** 62 52 6 0 2 2 0
Receptor - ligand complexes 206 180 12 0 7 7 0
Receptor - G protein complexes 5 2 3 0 0 0 0
Active-state receptors* 22 19 3 0 0 0 0
*Active state is defined as agonist-bound and opened intracellular TM bundle. **Receptor-orthologues are only counted once.

Specific sets of structures can be downloaded from the structure browser
The latest released structure is from 2019-03-06



By class By ligand type The number of unique receptor with structures available. The number of unique receptors GPCR-ligand complexes. The number of structures available. The number of unique crystallized receptors available. The number of unique GPCR-ligand complexes. The number of structures available.


Structural coverage of GPCR Classes


Class A
(Rhodopsin)




Class B1
(Secretin)

Class B2
(Adhesion)

Class C
(Glutamate)

Class F
(Frizzled)

Taste 2