Number of structures, including multiple of same receptor (complex)

Class
(Family)		 A (Rhodopsin) B1 (Secretin) B2 (Adhesion) C (Glutamate) D1
(Ste2-like fungal pheromone) 		F (Frizzled) T2 (Taste 2) Total
Receptors 1021 137 32 80 1 22 3 1296
Receptor - ligand complexes 1019 137 30 80 1 22 3 1292
Receptor - G protein complexes 524 112 31 8 1 6 3 685
Active-state receptors* 613 117 31 25 1 7 3 797


Number of unique receptor complexes

Class
(Family)		 A (Rhodopsin) B1 (Secretin) B2 (Adhesion) C (Glutamate) D1
(Ste2-like fungal pheromone) 		F (Frizzled) T2 (Taste 2) Total
Receptors** 160 15 9 10 1 4 1 200
Receptor - ligand complexes 672 91 13 49 1 16 2 844
Receptor - G protein complexes 139 15 9 4 1 2 1 171
Active-state receptors* 143 15 9 6 1 2 1 177
*Active state is defined as agonist-bound and opened intracellular TM bundle. **Receptor-orthologues are only counted once.

Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2024-01-10.



By class By ligand type The number of unique receptors with structures available. The number of unique receptors GPCR-ligand complexes. The number of structures available. The number of unique receptors with structures. The number of unique GPCR-ligand complexes. The number of structures available.


Structural coverage of GPCR Classes


Receptor names:

Class A
(Rhodopsin)


Structure state frequency (from low to high)
Structure state
○ Active ○ Intermediate ○ Inactive




Class A
Orphans

Class B1
(Secretin)

Class B2
(Adhesion)




Class C
(Glutamate)

Class F
(Frizzled)

Class T
(Taste 2)