Number of structures, including multiple of same receptor (complex)

Class (Family) Total Class A (Rhodopsin) Class B1 (Secretin) Class B2 (Adhesion) Class C (Glutamate) Class F (Frizzled) Taste 2
Receptors 310 278 15 0 6 11 0
Receptor - ligand complexes 302 271 14 0 6 11 0
Receptor - G protein complexes 6 2 4 0 0 0 0
Active-state receptors* 71 67 4 0 0 0 0


Number of unique receptor complexes

Class (Family) Total Class A (Rhodopsin) Class B1 (Secretin) Class B2 (Adhesion) Class C (Glutamate) Class F (Frizzled) Taste 2
Receptors** 59 50 6 0 2 1 0
Receptor - ligand complexes 200 176 11 0 6 7 0
Receptor - G protein complexes 5 2 3 0 0 0 0
Active-state receptors* 21 18 3 0 0 0 0
*Active state is defined as agonist-bound and opened intracellular TM bundle. **Receptor-orthologues are only counted once.

Specific sets of structures can be downloaded from the structure browser
The latest released structure is from 2019-01-16



By class By ligand type The number of unique receptor with structures available. The number of unique receptors GPCR-ligand complexes. The number of structures available. The number of unique crystallized receptors available. The number of unique GPCR-ligand complexes. The number of structures available.


Structural coverage of GPCR Classes


Class A
(Rhodopsin)




Class B1
(Secretin)

Class B2
(Adhesion)

Class C
(Glutamate)

Class F
(Frizzled)

Taste 2