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MODEL RECEPTOR TEMPLATE
Date
TAS2R1 2022-08-16 Active No TA2R1 TAS2R1 Taste 2 T (Taste 2) Human - - ta2r1_human
Olfactory receptor 51J1 2022-08-16 Active No O51J1 Olfactory 51J1 Olfactory A (Rhodopsin) Human - - o51j1_human
MRGPRG 2022-08-16 Active No MRGRG MRGPRG A orphans A (Rhodopsin) Human - - mrgrg_human
Olfactory receptor 51E1 2022-08-16 Inactive No O51E1 Olfactory 51E1 Olfactory A (Rhodopsin) Human - - o51e1_human
FZD10 2022-08-16 Active No FZD10 FZD10 Frizzled F (Frizzled) Human - - fzd10_human
LPA1 receptor 2022-08-16 Inactive No LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human - - lpar1_human
GPR84 2022-08-16 Active No GPR84 GPR84 A orphans A (Rhodopsin) Human - - gpr84_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5IUB 5iub
GPR19 2022-08-16 Inactive No GPR19 GPR19 A orphans A (Rhodopsin) Human - - gpr19_human
H3 receptor 2023-03-05 Inactive Yes HRH3 H3 Histamine A (Rhodopsin) Human H3 receptor 7F61 7f61
CB2 receptor 2022-10-26 Inactive Yes CNR2 CB2 Cannabinoid A (Rhodopsin) Human CB2 receptor 5ZTY 5zty
CCR5 2022-10-26 Inactive Yes CCR5 CCR5 Chemokine A (Rhodopsin) Human CCR5 4MBS 4mbs
ADGRL4 2022-08-16 Active No AGRL4 ADGRL4 ADGRL B2 (Adhesion) Human - - agrl4_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 6FK7 6fk7
Y1 receptor 2022-08-16 Active No NPY1R Y1 Neuropeptide Y A (Rhodopsin) Human - - npy1r_human
C5a1 receptor 2022-08-16 Inactive No C5AR1 C5a1 Complement peptide A (Rhodopsin) Human - - c5ar1_human
δ receptor 2022-08-16 Active No OPRD δ Opioid A (Rhodopsin) Human - - oprd_human
OX2 receptor 2023-03-05 Inactive Yes OX2R OX2 Orexin A (Rhodopsin) Human OX2 receptor 7XRR 7xrr
CaS receptor 2023-06-27 Active Yes CASR CaS Calcium-sensing C (Glutamate) Human CaS receptor 7DTT 7dtt
Rhodopsin 2023-06-14 Inactive Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 2I37 2i37
ADGRG1 2022-08-16 Inactive No AGRG1 ADGRG1 ADGRG B2 (Adhesion) Human - - agrg1_human
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 6OBA 6oba
ACKR3 2023-03-05 Active Yes ACKR3 ACKR3 Chemokine A (Rhodopsin) Human ACKR3 7SK9 7sk9
PAR1 2022-10-26 Intermediate Yes PAR1 PAR1 Proteinase-activated A (Rhodopsin) Human PAR1 3VW7 3vw7
M2 receptor 2022-10-26 Inactive Yes ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human M2 receptor 5ZK8 5zk8
M5 receptor 2022-10-26 Inactive Yes ACM5 M5 Acetylcholine (muscarinic) A (Rhodopsin) Human M5 receptor 6OL9 6ol9
α1A-adrenoceptor 2022-08-16 Active No ADA1A α1A Adrenoceptors A (Rhodopsin) Human - - ada1a_human
ETB receptor 2022-10-26 Inactive Yes EDNRB ETB Endothelin A (Rhodopsin) Human ETB receptor 6LRY 6lry
CaS receptor 2023-06-27 Active Yes CASR CaS Calcium-sensing C (Glutamate) Human CaS receptor 7E6T 7e6t
mGlu8 receptor 2022-08-16 Inactive No GRM8 mGlu8 Metabotropic glutamate C (Glutamate) Human - - grm8_human
M4 receptor 2022-08-16 Inactive No ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human - - acm4_human
mGlu5 receptor 2022-08-16 Active No GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human - - grm5_human
TAS2R10 2022-08-16 Active No T2R10 TAS2R10 Taste 2 T (Taste 2) Human - - t2r10_human
TAS2R7 2022-08-16 Active No TA2R7 TAS2R7 Taste 2 T (Taste 2) Human - - ta2r7_human
DP1 receptor 2022-08-16 Inactive No PD2R DP1 Prostanoid A (Rhodopsin) Human - - pd2r_human
GLP-1 receptor 2023-03-05 Active Yes GLP1R GLP-1 Glucagon B1 (Secretin) Human GLP-1 receptor 7S15 7s15
ADGRE4P 2022-08-16 Active No AGRE4 ADGRE4P ADGRE B2 (Adhesion) Human - - agre4_human
MC5 receptor 2022-08-16 Inactive No MC5R MC5 Melanocortin A (Rhodopsin) Human - - mc5r_human
Rhodopsin 2022-10-26 Inactive Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 5TE5 5te5
GPR33 2022-08-16 Inactive No GPR33 GPR33 A orphans A (Rhodopsin) Human - - gpr33_human
AT1 receptor 2022-10-26 Inactive Yes AGTR1 AT1 Angiotensin A (Rhodopsin) Human AT1 receptor 4YAY 4yay
GPR78 2022-08-16 Inactive No GPR78 GPR78 A orphans A (Rhodopsin) Human - - gpr78_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 5EN0 5en0
FZD2 2022-08-16 Active No FZD2 FZD2 Frizzled F (Frizzled) Human - - fzd2_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 3REY 3rey
apelin receptor 2023-03-05 Inactive Yes APJ apelin Apelin A (Rhodopsin) Human apelin receptor 7SUS 7sus
B1 receptor 2022-08-16 Inactive No BKRB1 B1 Bradykinin A (Rhodopsin) Human - - bkrb1_human
FFA1 receptor 2022-10-26 Intermediate Yes FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human FFA1 receptor 4PHU 4phu
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 6MH8 6mh8
GAL3 receptor 2022-08-16 Inactive No GALR3 GAL3 Galanin A (Rhodopsin) Human - - galr3_human
CysLT2 receptor 2022-08-16 Inactive No CLTR2 CysLT2 Leukotriene A (Rhodopsin) Human - - cltr2_human
motilin receptor 2022-08-16 Active No MTLR motilin Motilin A (Rhodopsin) Human - - mtlr_human
TAAR9 2022-08-16 Active No TAAR9 TAAR9 A orphans A (Rhodopsin) Human - - taar9_human
DP1 receptor 2022-08-16 Active No PD2R DP1 Prostanoid A (Rhodopsin) Human - - pd2r_human
NTS1 receptor 2023-06-14 Intermediate Yes NTR1 NTS1 Neurotensin A (Rhodopsin) Rat NTS1 receptor 6Z8N 6z8n
MT2 receptor 2022-10-26 Inactive Yes MTR1B MT2 Melatonin A (Rhodopsin) Human MT2 receptor 6ME8 6me8
NTS1 receptor 2022-10-26 Active Yes NTR1 NTS1 Neurotensin A (Rhodopsin) Human NTS1 receptor 6UP7 6up7
FFA4 receptor 2022-08-16 Active No FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human - - ffar4_human
5-HT2A receptor 2022-10-26 Inactive Yes 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2A receptor 6A94 6a94
CB2 receptor 2022-10-26 Inactive Yes CNR2 CB2 Cannabinoid A (Rhodopsin) Human CB2 receptor 6KPC 6kpc
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 6S0Q 6s0q
mGlu5 receptor 2022-10-26 Inactive Yes GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human mGlu5 receptor 6FFI 6ffi
NPBW1 receptor 2022-08-16 Active No NPBW1 NPBW1 Neuropeptide W/neuropeptide B A (Rhodopsin) Human - - npbw1_human
OX1 receptor 2022-10-26 Inactive Yes OX1R OX1 Orexin A (Rhodopsin) Human OX1 receptor 6TQ4 6tq4
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 6PS7 6ps7
GABAB2 2022-08-16 Active No GABR2 GABAB2 GABAB C (Glutamate) Human - - gabr2_human
chemerin receptor 2 2022-08-16 Inactive No CML2 chemerin 2 Chemerin receptor A (Rhodopsin) Human - - cml2_human
ghrelin receptor 2022-10-26 Inactive Yes GHSR ghrelin Ghrelin A (Rhodopsin) Human ghrelin receptor 7F83 7f83
GABAB1 2022-08-16 Inactive No GABR1 GABAB1 GABAB C (Glutamate) Human - - gabr1_human
SMO 2022-10-26 Inactive Yes SMO SMO Frizzled F (Frizzled) Human SMO 4QIN 4qin
S1P5 receptor 2022-08-16 Inactive No S1PR5 S1P5 Lysophospholipid (S1P) A (Rhodopsin) Human - - s1pr5_human
ADGRE5 2022-08-16 Active No AGRE5 ADGRE5 ADGRE B2 (Adhesion) Human - - agre5_human
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 4GBR 4gbr
secretin receptor 2022-08-16 Active No SCTR secretin Glucagon B1 (Secretin) Human - - sctr_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 6FK6 6fk6
GPR101 2022-08-16 Inactive No GP101 GPR101 A orphans A (Rhodopsin) Human - - gp101_human
MRGPRX2 2022-08-16 Inactive No MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human - - mrgx2_human
Olfactory receptor 51B6 2022-08-16 Inactive No O51B6 Olfactory 51B6 Olfactory A (Rhodopsin) Human - - o51b6_human
GPR88 2022-08-16 Active No GPR88 GPR88 A orphans A (Rhodopsin) Human - - gpr88_human
M5 receptor 2022-08-16 Inactive No ACM5 M5 Acetylcholine (muscarinic) A (Rhodopsin) Human - - acm5_human
OX1 receptor 2022-10-26 Inactive Yes OX1R OX1 Orexin A (Rhodopsin) Human OX1 receptor 6TP3 6tp3
Olfactory receptor 51S1 2022-08-16 Inactive No O51S1 Olfactory 51S1 Olfactory A (Rhodopsin) Human - - o51s1_human
CRF1 receptor 2022-08-16 Active No CRFR1 CRF1 Corticotropin-releasing factor B1 (Secretin) Human - - crfr1_human
D3 receptor 2022-10-26 Inactive Yes DRD3 D3 Dopamine A (Rhodopsin) Human D3 receptor 3PBL 3pbl
GPR6 2022-08-16 Active No GPR6 GPR6 A orphans A (Rhodopsin) Human - - gpr6_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 6AQF 6aqf
TAS2R5 2022-08-16 Inactive No TA2R5 TAS2R5 Taste 2 T (Taste 2) Human - - ta2r5_human
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 6PS5 6ps5
GPR176 2022-08-16 Active No GP176 GPR176 A orphans A (Rhodopsin) Human - - gp176_human
US28 2022-10-26 Active Yes Q80KM9 US28 Unclassified A (Rhodopsin) strain AD169 US28 5WB2 5wb2
FPR3 2022-08-16 Inactive No FPR3 FPR3 Formylpeptide A (Rhodopsin) Human - - fpr3_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 5WKT 5wkt
5-HT6 receptor 2022-08-16 Active No 5HT6R 5-HT6 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht6r_human
CB2 receptor 2022-08-16 Active No CNR2 CB2 Cannabinoid A (Rhodopsin) Human - - cnr2_human
mGlu2 receptor 2022-08-16 Inactive No GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human - - grm2_human
EP4 receptor 2022-08-16 Active No PE2R4 EP4 Prostanoid A (Rhodopsin) Human - - pe2r4_human
RXFP4 2022-08-16 Active No RL3R2 RXFP4 Relaxin family peptide A (Rhodopsin) Human - - rl3r2_human
ADGRA3 2022-08-16 Active No AGRA3 ADGRA3 ADGRA B2 (Adhesion) Human - - agra3_human
PAC1 receptor 2022-08-16 Active No PACR PAC1 VIP and PACAP B1 (Secretin) Human - - pacr_human
MC2 receptor 2022-08-16 Active No ACTHR MC2 Melanocortin A (Rhodopsin) Human - - acthr_human
FZD7 2022-08-16 Active No FZD7 FZD7 Frizzled F (Frizzled) Human - - fzd7_human
CysLT1 receptor 2022-08-16 Inactive No CLTR1 CysLT1 Leukotriene A (Rhodopsin) Human - - cltr1_human
Olfactory receptor 51Q1 2022-08-16 Inactive No O51Q1 Olfactory 51Q1 Olfactory A (Rhodopsin) Human - - o51q1_human
M1 receptor 2022-10-26 Inactive Yes ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human M1 receptor 5CXV 5cxv
GPR151 2022-08-16 Active No GP151 GPR151 A orphans A (Rhodopsin) Human - - gp151_human
5-HT2A receptor 2022-10-26 Inactive Yes 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2A receptor 6WH4 6wh4
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 3NY9 3ny9
TA1 receptor 2022-08-16 Active No TAAR1 TA1 Trace amine A (Rhodopsin) Human - - taar1_human
CXCR6 2022-08-16 Inactive No CXCR6 CXCR6 Chemokine A (Rhodopsin) Human - - cxcr6_human
NTS1 receptor 2022-10-26 Active Yes NTR1 NTS1 Neurotensin A (Rhodopsin) Rat NTS1 receptor 4XES 4xes
ACKR4 2022-08-16 Active No ACKR4 ACKR4 Chemokine A (Rhodopsin) Human - - ackr4_human
GPR63 2022-08-16 Active No GPR63 GPR63 A orphans A (Rhodopsin) Human - - gpr63_human
P2Y1 receptor 2022-08-16 Inactive No P2RY1 P2Y1 P2Y A (Rhodopsin) Human - - p2ry1_human
D1 receptor 2022-08-16 Inactive No DRD1 D1 Dopamine A (Rhodopsin) Human - - drd1_human
NK1 receptor 2022-10-26 Inactive Yes NK1R NK1 Tachykinin A (Rhodopsin) Human NK1 receptor 6J21 6j21
P2RY10 2022-08-16 Inactive No P2Y10 P2RY10 A orphans A (Rhodopsin) Human - - p2y10_human
MAS1L 2022-08-16 Inactive No MAS1L MAS1L A orphans A (Rhodopsin) Human - - mas1l_human
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 5D5A 5d5a
Olfactory receptor 51V1 2022-08-16 Inactive No O51V1 Olfactory 51V1 Olfactory A (Rhodopsin) Human - - o51v1_human
GLP-1 receptor 2022-08-16 Inactive No GLP1R GLP-1 Glucagon B1 (Secretin) Human - - glp1r_human
CysLT2 receptor 2022-10-26 Intermediate Yes CLTR2 CysLT2 Leukotriene A (Rhodopsin) Human CysLT2 receptor 6RZ7 6rz7
MRGPRD 2022-08-16 Active No MRGRD MRGPRD A orphans A (Rhodopsin) Human - - mrgrd_human
ACKR3 2023-03-05 Active Yes ACKR3 ACKR3 Chemokine A (Rhodopsin) Human ACKR3 7SK5 7sk5
TAS2R14 2022-08-16 Active No T2R14 TAS2R14 Taste 2 T (Taste 2) Human - - t2r14_human
CCR3 2022-08-16 Active No CCR3 CCR3 Chemokine A (Rhodopsin) Human - - ccr3_human
GPR160 2022-08-16 Inactive No GP160 GPR160 A orphans A (Rhodopsin) Human - - gp160_human
ADGRL3 2022-08-16 Inactive No AGRL3 ADGRL3 ADGRL B2 (Adhesion) Human - - agrl3_human
GPR39 2022-08-16 Active No GPR39 GPR39 A orphans A (Rhodopsin) Human - - gpr39_human
CCK2 receptor 2022-08-16 Inactive No GASR CCK2 Cholecystokinin A (Rhodopsin) Human - - gasr_human
ADGRG4 2022-08-16 Active No AGRG4 ADGRG4 ADGRG B2 (Adhesion) Human - - agrg4_human
SMO 2022-10-26 Inactive Yes SMO SMO Frizzled F (Frizzled) Human SMO 4N4W 4n4w
GPR22 2022-08-16 Active No GPR22 GPR22 A orphans A (Rhodopsin) Human - - gpr22_human
S1P4 receptor 2022-08-16 Active No S1PR4 S1P4 Lysophospholipid (S1P) A (Rhodopsin) Human - - s1pr4_human
ACKR2 2022-08-16 Inactive No ACKR2 ACKR2 Chemokine A (Rhodopsin) Human - - ackr2_human
SMO 2022-10-26 Active Yes Q98SW5 SMO Frizzled F (Frizzled) African clawed frog SMO 6D35 6d35
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 6GT3 6gt3
TAS2R31 2022-08-16 Active No T2R31 TAS2R31 Taste 2 T (Taste 2) Human - - t2r31_human
β1-adrenoceptor 2022-10-26 Inactive Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Human β1-adrenoceptor 7BVQ 7bvq
Olfactory receptor 51A7 2022-08-16 Inactive No O51A7 Olfactory 51A7 Olfactory A (Rhodopsin) Human - - o51a7_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 6LPK 6lpk
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 2X72 2x72
HCA1 receptor 2022-08-16 Active No HCAR1 HCA1 Hydroxycarboxylic acid A (Rhodopsin) Human - - hcar1_human
MC1 receptor 2022-08-16 Inactive No MSHR MC1 Melanocortin A (Rhodopsin) Human - - mshr_human
P2Y1 receptor 2022-10-26 Intermediate Yes P2RY1 P2Y1 P2Y A (Rhodopsin) Human P2Y1 receptor 4XNW 4xnw
OXE receptor 2022-08-16 Inactive No OXER1 OXE Leukotriene A (Rhodopsin) Human - - oxer1_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 7MT8 7mt8
D4 receptor 2022-10-26 Inactive Yes DRD4 D4 Dopamine A (Rhodopsin) Mouse D4 receptor 6IQL 6iql
glucagon receptor 2022-08-16 Inactive No GLR glucagon Glucagon B1 (Secretin) Human - - glr_human
GLP-1 receptor 2022-10-26 Inactive Yes GLP1R GLP-1 Glucagon B1 (Secretin) Human GLP-1 receptor 5VEX 5vex
μ receptor 2022-08-16 Active No OPRM μ Opioid A (Rhodopsin) Human - - oprm_human
CCR6 2022-08-16 Inactive No CCR6 CCR6 Chemokine A (Rhodopsin) Human - - ccr6_human
AT1 receptor 2022-10-26 Active Yes AGTR1 AT1 Angiotensin A (Rhodopsin) Human AT1 receptor 6DO1 6do1
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 7MTB 7mtb
A2A receptor 2023-06-12 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 8FYN 8fyn
TAS2R50 2022-08-16 Active No T2R50 TAS2R50 Taste 2 T (Taste 2) Human - - t2r50_human
β1-adrenoceptor 2022-10-26 Inactive Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 2Y03 2y03
MCH1 receptor 2022-08-16 Active No MCHR1 MCH1 Melanin-concentrating hormone A (Rhodopsin) Human - - mchr1_human
PAR4 2022-08-16 Active No PAR4 PAR4 Proteinase-activated A (Rhodopsin) Human - - par4_human
TAS2R46 2022-08-16 Inactive No T2R46 TAS2R46 Taste 2 T (Taste 2) Human - - t2r46_human
ghrelin receptor 2022-08-16 Inactive No GHSR ghrelin Ghrelin A (Rhodopsin) Human - - ghsr_human
ETB receptor 2022-10-26 Inactive Yes EDNRB ETB Endothelin A (Rhodopsin) Human ETB receptor 5GLI 5gli
κ receptor 2022-10-26 Inactive Yes OPRK κ Opioid A (Rhodopsin) Human κ receptor 4DJH 4djh
NPFF1 receptor 2022-08-16 Active No NPFF1 NPFF1 Neuropeptide FF/neuropeptide AF A (Rhodopsin) Human - - npff1_human
GPR22 2022-08-16 Inactive No GPR22 GPR22 A orphans A (Rhodopsin) Human - - gpr22_human
LGR4 2022-08-16 Inactive No LGR4 LGR4 A orphans A (Rhodopsin) Human - - lgr4_human
5-HT2A receptor 2022-10-26 Inactive Yes 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2A receptor 7WC9 7wc9
β1-adrenoceptor 2022-10-26 Inactive Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 4AMJ 4amj
SMO 2023-03-05 Inactive Yes SMO SMO Frizzled F (Frizzled) Mouse SMO 8CXO 8cxo
mGlu2 receptor 2022-10-26 Inactive Yes GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human mGlu2 receptor 7EPE 7epe
GPR158 2022-08-16 Inactive No GP158 GPR158 C Orphans C (Glutamate) Human - - gp158_human
PTH1 receptor 2022-08-16 Inactive No PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human - - pth1r_human
succinate receptor 2022-08-16 Inactive No SUCR1 succinate Succinate A (Rhodopsin) Human - - sucr1_human
MT2 receptor 2022-10-26 Inactive Yes MTR1B MT2 Melatonin A (Rhodopsin) Human MT2 receptor 6ME9 6me9
CCR5 2022-10-26 Inactive Yes CCR5 CCR5 Chemokine A (Rhodopsin) Human CCR5 6MET 6met
BLT1 receptor 2022-10-26 Inactive Yes Q9WTK1 BLT1 Leukotriene A (Rhodopsin) Guinea pig BLT1 receptor 5X33 5x33
CT receptor 2022-08-16 Active No CALCR CT Calcitonin B1 (Secretin) Human - - calcr_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 7PYR 7pyr
GPR78 2022-08-16 Active No GPR78 GPR78 A orphans A (Rhodopsin) Human - - gpr78_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 3UZA 3uza
5-HT1F receptor 2022-08-16 Inactive No 5HT1F 5-HT1F 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht1f_human
GHRH receptor 2022-08-16 Active No GHRHR GHRH Glucagon B1 (Secretin) Human - - ghrhr_human
TAS2R46 2022-08-16 Active No T2R46 TAS2R46 Taste 2 T (Taste 2) Human - - t2r46_human
UT receptor 2022-08-16 Active No UR2R UT Urotensin A (Rhodopsin) Human - - ur2r_human
C3a receptor 2022-08-16 Inactive No C3AR C3a Complement peptide A (Rhodopsin) Human - - c3ar_human
GPR32 2022-08-16 Inactive No GPR32 GPR32 A orphans A (Rhodopsin) Human - - gpr32_human
D2 receptor 2022-08-16 Active No DRD2 D2 Dopamine A (Rhodopsin) Human - - drd2_human
GPR150 2022-08-16 Active No GP150 GPR150 A orphans A (Rhodopsin) Human - - gp150_human
BLT2 receptor 2022-08-16 Active No LT4R2 BLT2 Leukotriene A (Rhodopsin) Human - - lt4r2_human
M1 receptor 2022-10-26 Inactive Yes ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human M1 receptor 6ZG4 6zg4
GPR85 2022-08-16 Inactive No GPR85 GPR85 A orphans A (Rhodopsin) Human - - gpr85_human
C5a1 receptor 2022-08-16 Active No C5AR1 C5a1 Complement peptide A (Rhodopsin) Human - - c5ar1_human
SMO 2022-08-16 Active No SMO SMO Frizzled F (Frizzled) Human - - smo_human
VPAC1 receptor 2022-08-16 Active No VIPR1 VPAC1 VIP and PACAP B1 (Secretin) Human - - vipr1_human
GPRC5C 2022-08-16 Active No GPC5C GPRC5C C Orphans C (Glutamate) Human - - gpc5c_human
GPR135 2022-08-16 Active No GP135 GPR135 A orphans A (Rhodopsin) Human - - gp135_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 7MT9 7mt9
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 7ARO 7aro
y6 receptor 2022-08-16 Inactive No NPY6R y6 Neuropeptide Y A (Rhodopsin) Human - - npy6r_human
GPR63 2022-08-16 Inactive No GPR63 GPR63 A orphans A (Rhodopsin) Human - - gpr63_human
M3 receptor 2022-08-16 Inactive No ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Human - - acm3_human
5-HT5A receptor 2022-08-16 Inactive No 5HT5A 5-HT5A 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht5a_human
GPR83 2022-08-16 Inactive No GPR83 GPR83 A orphans A (Rhodopsin) Human - - gpr83_human
GPR3 2022-08-16 Inactive No GPR3 GPR3 A orphans A (Rhodopsin) Human - - gpr3_human
glucagon receptor 2022-10-26 Inactive Yes GLR glucagon Glucagon B1 (Secretin) Human glucagon receptor 5XEZ 5xez
IP receptor 2022-08-16 Inactive No PI2R IP Prostanoid A (Rhodopsin) Human - - pi2r_human
M4 receptor 2022-10-26 Inactive Yes ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human M4 receptor 5DSG 5dsg
LPA1 receptor 2022-10-26 Inactive Yes LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human LPA1 receptor 4Z36 4z36
δ receptor 2022-10-26 Active Yes OPRD δ Opioid A (Rhodopsin) Human δ receptor 6PT3 6pt3
CXCR4 2022-10-26 Inactive Yes CXCR4 CXCR4 Chemokine A (Rhodopsin) Human CXCR4 4RWS 4rws
A2A receptor 2022-10-26 Active Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 4UHR 4uhr
CXCR3 2022-08-16 Active No CXCR3 CXCR3 Chemokine A (Rhodopsin) Human - - cxcr3_human
ACKR3 2022-08-16 Active No ACKR3 ACKR3 Chemokine A (Rhodopsin) Human - - ackr3_human
TAS2R19 2022-08-16 Active No T2R19 TAS2R19 Taste 2 T (Taste 2) Human - - t2r19_human
ADGRG3 2022-08-16 Active No AGRG3 ADGRG3 ADGRG B2 (Adhesion) Human - - agrg3_human
5-HT2B receptor 2022-10-26 Intermediate Yes 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2B receptor 6DS0 6ds0
GPR4 2022-08-16 Inactive No GPR4 GPR4 A orphans A (Rhodopsin) Human - - gpr4_human
FFA2 receptor 2022-08-16 Active No FFAR2 FFA2 Free fatty acid A (Rhodopsin) Human - - ffar2_human
FZD3 2022-08-16 Inactive No FZD3 FZD3 Frizzled F (Frizzled) Human - - fzd3_human
β1-adrenoceptor 2022-10-26 Inactive Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 4BVN 4bvn
glucagon receptor 2022-10-26 Inactive Yes GLR glucagon Glucagon B1 (Secretin) Human glucagon receptor 4L6R 4l6r
SMO 2022-10-26 Inactive Yes SMO SMO Frizzled F (Frizzled) Human SMO 5V57 5v57
Olfactory receptor 51F1 2022-08-16 Inactive No O51F1 Olfactory 51F1 Olfactory A (Rhodopsin) Human - - o51f1_human
OX2 receptor 2022-10-26 Inactive Yes OX2R OX2 Orexin A (Rhodopsin) Human OX2 receptor 4S0V 4s0v
MRGPRX3 2022-08-16 Inactive No MRGX3 MRGPRX3 A orphans A (Rhodopsin) Human - - mrgx3_human
ACKR1 2022-08-16 Active No ACKR1 ACKR1 Chemokine A (Rhodopsin) Human - - ackr1_human
CXCR4 2023-06-14 Inactive Yes CXCR4 CXCR4 Chemokine A (Rhodopsin) Human CXCR4 3OE8 3oe8
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 6FKB 6fkb
A1 receptor 2022-08-16 Inactive No AA1R A1 Adenosine A (Rhodopsin) Human - - aa1r_human
D4 receptor 2022-08-16 Inactive No DRD4 D4 Dopamine A (Rhodopsin) Human - - drd4_human
ADGRA1 2022-08-16 Active No AGRA1 ADGRA1 ADGRA B2 (Adhesion) Human - - agra1_human
S1P1 receptor 2022-10-26 Inactive Yes S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human S1P1 receptor 3V2Y 3v2y
CysLT1 receptor 2022-10-26 Intermediate Yes CLTR1 CysLT1 Leukotriene A (Rhodopsin) Human CysLT1 receptor 6RZ5 6rz5
OPN4 2022-08-16 Inactive No OPN4 OPN4 Opsins A (Rhodopsin) Human - - opn4_human
5-HT7 receptor 2022-08-16 Inactive No 5HT7R 5-HT7 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht7r_human
NMU2 receptor 2022-08-16 Active No NMUR2 NMU2 Neuromedin U A (Rhodopsin) Human - - nmur2_human
OX1 receptor 2022-10-26 Inactive Yes OX1R OX1 Orexin A (Rhodopsin) Human OX1 receptor 6TOT 6tot
NPFF2 receptor 2022-08-16 Active No NPFF2 NPFF2 Neuropeptide FF/neuropeptide AF A (Rhodopsin) Human - - npff2_human
GABAB1 2022-08-16 Active No GABR1 GABAB1 GABAB C (Glutamate) Human - - gabr1_human
CCK1 receptor 2022-10-26 Inactive Yes CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human CCK1 receptor 7F8Y 7f8y
M4 receptor 2022-08-16 Active No ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human - - acm4_human
ADGRF4 2022-08-16 Active No AGRF4 ADGRF4 ADGRF B2 (Adhesion) Human - - agrf4_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 6FKA 6fka
EP2 receptor 2022-08-16 Inactive No PE2R2 EP2 Prostanoid A (Rhodopsin) Human - - pe2r2_human
H1 receptor 2022-08-16 Active No HRH1 H1 Histamine A (Rhodopsin) Human - - hrh1_human
NK3 receptor 2022-08-16 Active No NK3R NK3 Tachykinin A (Rhodopsin) Human - - nk3r_human
α1D-adrenoceptor 2022-08-16 Active No ADA1D α1D Adrenoceptors A (Rhodopsin) Human - - ada1d_human
5-HT2A receptor 2022-10-26 Inactive Yes 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2A receptor 7WC7 7wc7
TAAR2 2022-08-16 Active No TAAR2 TAAR2 A orphans A (Rhodopsin) Human - - taar2_human
β1-adrenoceptor 2022-10-26 Inactive Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 4AMI 4ami
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 3D4S 3d4s
ETA receptor 2022-08-16 Inactive No EDNRA ETA Endothelin A (Rhodopsin) Human - - ednra_human
GLP-2 receptor 2022-08-16 Active No GLP2R GLP-2 Glucagon B1 (Secretin) Human - - glp2r_human
5-HT1B receptor 2022-10-26 Inactive Yes 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT1B receptor 4IAQ 4iaq
TAS2R39 2022-08-16 Inactive No T2R39 TAS2R39 Taste 2 T (Taste 2) Human - - t2r39_human
A1 receptor 2022-10-26 Inactive Yes AA1R A1 Adenosine A (Rhodopsin) Human A1 receptor 5N2S 5n2s
C5a2 receptor 2022-08-16 Active No C5AR2 C5a2 Complement peptide A (Rhodopsin) Human - - c5ar2_human
β2-adrenoceptor 2022-10-26 Active Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 6N48 6n48
Y5 receptor 2022-08-16 Active No NPY5R Y5 Neuropeptide Y A (Rhodopsin) Human - - npy5r_human
MCH2 receptor 2022-08-16 Inactive No MCHR2 MCH2 Melanin-concentrating hormone A (Rhodopsin) Human - - mchr2_human
β1-adrenoceptor 2022-10-26 Active Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 6H7M 6h7m
M3 receptor 2022-08-16 Active No ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Human - - acm3_human
MRGPRF 2022-08-16 Inactive No MRGRF MRGPRF A orphans A (Rhodopsin) Human - - mrgrf_human
SMO 2022-10-26 Inactive Yes SMO SMO Frizzled F (Frizzled) Human SMO 5L7D 5l7d
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5K2A 5k2a
Olfactory receptor 2T11 2022-08-16 Inactive No O2T11 Olfactory 2T11 Olfactory A (Rhodopsin) Human - - o2t11_human
GIP receptor 2022-08-16 Inactive No GIPR GIP Glucagon B1 (Secretin) Human - - gipr_human
CCK2 receptor 2022-08-16 Active No GASR CCK2 Cholecystokinin A (Rhodopsin) Human - - gasr_human
TAAR6 2022-08-16 Active No TAAR6 TAAR6 A orphans A (Rhodopsin) Human - - taar6_human
GPR158 2022-10-26 Inactive Yes GP158 GPR158 C Orphans C (Glutamate) Human GPR158 7SHF 7shf
NOP receptor 2022-10-26 Inactive Yes OPRX NOP Opioid A (Rhodopsin) Human NOP receptor 5DHG 5dhg
GPR68 2022-08-16 Active No OGR1 GPR68 A orphans A (Rhodopsin) Human - - ogr1_human
GPR153 2022-08-16 Inactive No GP153 GPR153 A orphans A (Rhodopsin) Human - - gp153_human
TAS2R30 2022-08-16 Active No T2R30 TAS2R30 Taste 2 T (Taste 2) Human - - t2r30_human
S1P3 receptor 2022-08-16 Inactive No S1PR3 S1P3 Lysophospholipid (S1P) A (Rhodopsin) Human - - s1pr3_human
ghrelin receptor 2022-10-26 Inactive Yes GHSR ghrelin Ghrelin A (Rhodopsin) Human ghrelin receptor 6KO5 6ko5
calcitonin receptor-like receptor 2022-08-16 Inactive No CALRL calcitonin-like Calcitonin B1 (Secretin) Human - - calrl_human
GPR50 2022-08-16 Inactive No MTR1L GPR50 A orphans A (Rhodopsin) Human - - mtr1l_human
MRGPRX2 2022-10-26 Active Yes MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human MRGPRX2 7VV4 7vv4
M2 receptor 2022-10-26 Inactive Yes ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human M2 receptor 5ZK3 5zk3
CX3CR1 2022-08-16 Inactive No CX3C1 CX3CR1 Chemokine A (Rhodopsin) Human - - cx3c1_human
TSH receptor 2022-08-16 Inactive No TSHR TSH Glycoprotein hormone A (Rhodopsin) Human - - tshr_human
A1 receptor 2022-10-26 Inactive Yes AA1R A1 Adenosine A (Rhodopsin) Human A1 receptor 5UEN 5uen
GPR27 2022-08-16 Inactive No GPR27 GPR27 A orphans A (Rhodopsin) Human - - gpr27_human
κ receptor 2022-10-26 Active Yes OPRK κ Opioid A (Rhodopsin) Human κ receptor 6B73 6b73
α2A-adrenoceptor 2022-10-26 Inactive Yes ADA2A α2A Adrenoceptors A (Rhodopsin) Human α2A-adrenoceptor 6KUY 6kuy
EP4 receptor 2022-08-16 Inactive No PE2R4 EP4 Prostanoid A (Rhodopsin) Human - - pe2r4_human
NK1 receptor 2022-10-26 Inactive Yes NK1R NK1 Tachykinin A (Rhodopsin) Human NK1 receptor 6J20 6j20
M4 receptor 2022-10-26 Inactive Yes ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human M4 receptor 6KP6 6kp6
CCK1 receptor 2022-10-26 Inactive Yes CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human CCK1 receptor 7F8X 7f8x
y6 receptor 2022-08-16 Active No NPY6R y6 Neuropeptide Y A (Rhodopsin) Human - - npy6r_human
TAAR5 2022-08-16 Inactive No TAAR5 TAAR5 A orphans A (Rhodopsin) Human - - taar5_human
PKR1 2022-08-16 Inactive No PKR1 PKR1 Prokineticin A (Rhodopsin) Human - - pkr1_human
β1-adrenoceptor 2022-10-26 Active Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 6H7O 6h7o
A2A receptor 2023-03-05 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 8DU3 8du3
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5OLZ 5olz
TAS2R9 2022-08-16 Inactive No TA2R9 TAS2R9 Taste 2 T (Taste 2) Human - - ta2r9_human
FZD4 2022-08-16 Active No FZD4 FZD4 Frizzled F (Frizzled) Human - - fzd4_human
Rhodopsin 2022-10-26 Inactive Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 1F88 1f88
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5OLO 5olo
GPR173 2022-08-16 Inactive No GP173 GPR173 A orphans A (Rhodopsin) Human - - gp173_human
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 5D5B 5d5b
PAR2 2022-10-26 Intermediate Yes PAR2 PAR2 Proteinase-activated A (Rhodopsin) Human PAR2 5NDD 5ndd
GPR142 2022-08-16 Inactive No GP142 GPR142 A orphans A (Rhodopsin) Human - - gp142_human
LPA1 receptor 2022-10-26 Inactive Yes LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human LPA1 receptor 4Z34 4z34
Olfactory receptor 51I2 2022-08-16 Active No O51I2 Olfactory 51I2 Olfactory A (Rhodopsin) Human - - o51i2_human
ADGRE3 2022-08-16 Active No AGRE3 ADGRE3 ADGRE B2 (Adhesion) Human - - agre3_human
GPR18 2022-08-16 Inactive No GPR18 GPR18 GPR18, GPR55 and GPR119 A (Rhodopsin) Human - - gpr18_human
mGlu2 receptor 2022-10-26 Inactive Yes GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human mGlu2 receptor 7EPD 7epd
GAL3 receptor 2022-08-16 Active No GALR3 GAL3 Galanin A (Rhodopsin) Human - - galr3_human
ACKR3 2023-03-05 Active Yes ACKR3 ACKR3 Chemokine A (Rhodopsin) Human ACKR3 7SK8 7sk8
TAS2R45 2022-08-16 Inactive No T2R45 TAS2R45 Taste 2 T (Taste 2) Human - - t2r45_human
succinate receptor 2022-10-26 Intermediate Yes SUCR1 succinate Succinate A (Rhodopsin) Rat succinate receptor 6RNK 6rnk
β1-adrenoceptor 2022-10-26 Inactive Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 2Y02 2y02
GPR42 2022-08-16 Active No GPR42 GPR42 Free fatty acid A (Rhodopsin) Human - - gpr42_human
EP3 receptor 2022-10-26 Active Yes PE2R3 EP3 Prostanoid A (Rhodopsin) Human EP3 receptor 6M9T 6m9t
ADGRE2 2022-08-16 Inactive No AGRE2 ADGRE2 ADGRE B2 (Adhesion) Human - - agre2_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 7MTA 7mta
5-HT2C receptor 2022-08-16 Inactive No 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht2c_human
ADGRF3 2022-08-16 Inactive No AGRF3 ADGRF3 ADGRF B2 (Adhesion) Human - - agrf3_human
NTS1 receptor 2022-10-26 Inactive Yes NTR1 NTS1 Neurotensin A (Rhodopsin) Rat NTS1 receptor 4BUO 4buo
GPR119 2022-08-16 Active No GP119 GPR119 GPR18, GPR55 and GPR119 A (Rhodopsin) Human - - gp119_human
NPS receptor 2022-08-16 Active No NPSR1 NPS Neuropeptide S A (Rhodopsin) Human - - npsr1_human
β2-adrenoceptor 2022-10-26 Active Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 4QKX 4qkx
CXCR4 2022-08-16 Active No CXCR4 CXCR4 Chemokine A (Rhodopsin) Human - - cxcr4_human
mGlu5 receptor 2022-10-26 Inactive Yes GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human mGlu5 receptor 5CGC 5cgc
GPR137 2022-08-16 Active No G137A GPR137 Other GPCR orphans Other GPCRs Human - - g137a_human
OPN5 2022-08-16 Inactive No OPN5 OPN5 Opsins A (Rhodopsin) Human - - opn5_human
MC2 receptor 2022-08-16 Inactive No ACTHR MC2 Melanocortin A (Rhodopsin) Human - - acthr_human
κ receptor 2022-08-16 Inactive No OPRK κ Opioid A (Rhodopsin) Human - - oprk_human
AT1 receptor 2022-08-16 Active No AGTR1 AT1 Angiotensin A (Rhodopsin) Human - - agtr1_human
GPR52 2022-08-16 Inactive No GPR52 GPR52 A orphans A (Rhodopsin) Human - - gpr52_human
α2C-adrenoceptor 2022-08-16 Inactive No ADA2C α2C Adrenoceptors A (Rhodopsin) Human - - ada2c_human
GLP-1 receptor 2022-10-26 Inactive Yes GLP1R GLP-1 Glucagon B1 (Secretin) Human GLP-1 receptor 6LN2 6ln2
AT2 receptor 2022-10-26 Active Yes AGTR2 AT2 Angiotensin A (Rhodopsin) Human AT2 receptor 5UNG 5ung
TAS2R41 2022-08-16 Inactive No T2R41 TAS2R41 Taste 2 T (Taste 2) Human - - t2r41_human
FFA2 receptor 2022-08-16 Inactive No FFAR2 FFA2 Free fatty acid A (Rhodopsin) Human - - ffar2_human
CELSR3 2022-08-16 Active No CELR3 CELSR3 ADGRC B2 (Adhesion) Human - - celr3_human
SMO 2022-10-26 Inactive Yes SMO SMO Frizzled F (Frizzled) Human SMO 4QIM 4qim
NTS1 receptor 2023-06-14 Inactive Yes NTR1 NTS1 Neurotensin A (Rhodopsin) Rat NTS1 receptor 3ZEV 3zev
GAL1 receptor 2022-08-16 Active No GALR1 GAL1 Galanin A (Rhodopsin) Human - - galr1_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 6FK8 6fk8
succinate receptor 2022-10-26 Intermediate Yes SUCR1 succinate Succinate A (Rhodopsin) Rat succinate receptor 6IBB 6ibb
TAAR8 2022-08-16 Active No TAAR8 TAAR8 A orphans A (Rhodopsin) Human - - taar8_human
M1 receptor 2022-08-16 Active No ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human - - acm1_human
GPR62 2022-08-16 Inactive No GPR62 GPR62 A orphans A (Rhodopsin) Human - - gpr62_human
GPR45 2022-08-16 Active No GPR45 GPR45 A orphans A (Rhodopsin) Human - - gpr45_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5K2B 5k2b
Olfactory receptor 51S1 2022-08-16 Active No O51S1 Olfactory 51S1 Olfactory A (Rhodopsin) Human - - o51s1_human
OT receptor 2022-08-16 Active No OXYR OT Vasopressin and oxytocin A (Rhodopsin) Human - - oxyr_human
ghrelin receptor 2022-10-26 Active Yes GHSR ghrelin Ghrelin A (Rhodopsin) Human ghrelin receptor 7F9Z 7f9z
CCR5 2022-10-26 Inactive Yes CCR5 CCR5 Chemokine A (Rhodopsin) Human CCR5 6AKY 6aky
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 6PRZ 6prz
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 6FKD 6fkd
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 6WQA 6wqa
NK1 receptor 2022-10-26 Inactive Yes NK1R NK1 Tachykinin A (Rhodopsin) Human NK1 receptor 6HLL 6hll
ADGRB1 2022-08-16 Active No AGRB1 ADGRB1 ADGRB B2 (Adhesion) Human - - agrb1_human
GPR31 2022-08-16 Active No GPR31 GPR31 A orphans A (Rhodopsin) Human - - gpr31_human
ADGRF3 2022-08-16 Active No AGRF3 ADGRF3 ADGRF B2 (Adhesion) Human - - agrf3_human
CysLT2 receptor 2022-10-26 Intermediate Yes CLTR2 CysLT2 Leukotriene A (Rhodopsin) Human CysLT2 receptor 6RZ8 6rz8
MAS1L 2022-08-16 Active No MAS1L MAS1L A orphans A (Rhodopsin) Human - - mas1l_human
M2 receptor 2022-08-16 Active No ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human - - acm2_human
Olfactory receptor 51G1 2022-08-16 Inactive No O51G1 Olfactory 51G1 Olfactory A (Rhodopsin) Human - - o51g1_human
MC1 receptor 2022-08-16 Active No MSHR MC1 Melanocortin A (Rhodopsin) Human - - mshr_human
HCA1 receptor 2022-08-16 Inactive No HCAR1 HCA1 Hydroxycarboxylic acid A (Rhodopsin) Human - - hcar1_human
Rhodopsin 2022-10-26 Inactive Yes OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid Rhodopsin 4WW3 4ww3
OX1 receptor 2022-10-26 Inactive Yes OX1R OX1 Orexin A (Rhodopsin) Human OX1 receptor 6V9S 6v9s
5-HT2B receptor 2022-10-26 Intermediate Yes 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2B receptor 6DRZ 6drz
LPA5 receptor 2022-08-16 Active No LPAR5 LPA5 Lysophospholipid (LPA) A (Rhodopsin) Human - - lpar5_human
GLP-1 receptor 2022-10-26 Inactive Yes GLP1R GLP-1 Glucagon B1 (Secretin) Human GLP-1 receptor 6KK1 6kk1
AT1 receptor 2022-08-16 Inactive No AGTR1 AT1 Angiotensin A (Rhodopsin) Human - - agtr1_human
M2 receptor 2022-10-26 Active Yes ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human M2 receptor 6U1N 6u1n
GPR153 2022-08-16 Active No GP153 GPR153 A orphans A (Rhodopsin) Human - - gp153_human
M1 receptor 2022-10-26 Inactive Yes ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human M1 receptor 6ZG9 6zg9
TAS2R50 2022-08-16 Inactive No T2R50 TAS2R50 Taste 2 T (Taste 2) Human - - t2r50_human
TAS1R1 2022-08-16 Active No TS1R1 TAS1R1 Taste 1 C (Glutamate) Human - - ts1r1_human
δ receptor 2022-10-26 Inactive Yes OPRD δ Opioid A (Rhodopsin) Human δ receptor 4N6H 4n6h
PAR2 2022-08-16 Active No PAR2 PAR2 Proteinase-activated A (Rhodopsin) Human - - par2_human
MT1 receptor 2022-10-26 Inactive Yes MTR1A MT1 Melatonin A (Rhodopsin) Human MT1 receptor 6PS8 6ps8
mGlu2 receptor 2022-08-16 Active No GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human - - grm2_human
NTS1 receptor 2022-10-26 Active Yes NTR1 NTS1 Neurotensin A (Rhodopsin) Rat NTS1 receptor 4XEE 4xee
FPR2/ALX 2022-08-16 Active No FPR2 FPR2/ALX Formylpeptide A (Rhodopsin) Human - - fpr2_human
SST2 receptor 2023-06-14 Inactive Yes SSR2 SST2 Somatostatin A (Rhodopsin) Human SST2 receptor 7UL5 7ul5
GPR39 2022-08-16 Inactive No GPR39 GPR39 A orphans A (Rhodopsin) Human - - gpr39_human
NPBW2 receptor 2022-08-16 Active No NPBW2 NPBW2 Neuropeptide W/neuropeptide B A (Rhodopsin) Human - - npbw2_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 6FKC 6fkc
5-HT4 receptor 2022-08-16 Inactive No 5HT4R 5-HT4 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht4r_human
mGlu5 receptor 2022-10-26 Intermediate Yes GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human mGlu5 receptor 6N51 6n51
Olfactory receptor 51D1 2022-08-16 Active No O51D1 Olfactory 51D1 Olfactory A (Rhodopsin) Human - - o51d1_human
Olfactory receptor 1A1 2022-08-16 Active No OR1A1 Olfactory 1A1 Olfactory A (Rhodopsin) Human - - or1a1_human
LPA2 receptor 2022-08-16 Inactive No LPAR2 LPA2 Lysophospholipid (LPA) A (Rhodopsin) Human - - lpar2_human
LPA2 receptor 2022-08-16 Active No LPAR2 LPA2 Lysophospholipid (LPA) A (Rhodopsin) Human - - lpar2_human
TAS2R5 2022-08-16 Active No TA2R5 TAS2R5 Taste 2 T (Taste 2) Human - - ta2r5_human
μ receptor 2022-10-26 Active Yes OPRM μ Opioid A (Rhodopsin) Mouse μ receptor 5C1M 5c1m
NMU2 receptor 2022-08-16 Inactive No NMUR2 NMU2 Neuromedin U A (Rhodopsin) Human - - nmur2_human
GPR83 2022-08-16 Active No GPR83 GPR83 A orphans A (Rhodopsin) Human - - gpr83_human
ADGRF2 2022-08-16 Active No AGRF2 ADGRF2 ADGRF B2 (Adhesion) Human - - agrf2_human
glucagon receptor 2022-10-26 Inactive Yes GLR glucagon Glucagon B1 (Secretin) Human glucagon receptor 5YQZ 5yqz
RXFP3 2022-08-16 Active No RL3R1 RXFP3 Relaxin family peptide A (Rhodopsin) Human - - rl3r1_human
MC3 receptor 2022-08-16 Inactive No MC3R MC3 Melanocortin A (Rhodopsin) Human - - mc3r_human
mGlu1 receptor 2023-06-27 Intermediate Yes GRM1 mGlu1 Metabotropic glutamate C (Glutamate) Human mGlu1 receptor 7DGE 7dge
TPRA1 2022-08-16 Inactive No TPRA1 TPRA1 Other GPCR orphans Other GPCRs Human - - tpra1_human
A2A receptor 2023-03-05 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 7T32 7t32
ADGRF1 2022-08-16 Active No AGRF1 ADGRF1 ADGRF B2 (Adhesion) Human - - agrf1_human
TAS1R2 2022-08-16 Active No TS1R2 TAS1R2 Taste 1 C (Glutamate) Human - - ts1r2_human
SMO 2022-10-26 Inactive Yes SMO SMO Frizzled F (Frizzled) Human SMO 5V56 5v56
GPR75 2022-08-16 Inactive No GPR75 GPR75 A orphans A (Rhodopsin) Human - - gpr75_human
Olfactory receptor 51B6 2022-08-16 Active No O51B6 Olfactory 51B6 Olfactory A (Rhodopsin) Human - - o51b6_human
ADGRD2 2022-08-16 Inactive No AGRD2 ADGRD2 ADGRD B2 (Adhesion) Human - - agrd2_human
Rhodopsin 2023-06-14 Inactive Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 2G87 2g87
MRGPRX2 2022-10-26 Active Yes MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human MRGPRX2 7VV6 7vv6
FZD1 2022-08-16 Active No FZD1 FZD1 Frizzled F (Frizzled) Human - - fzd1_human
5-HT2A receptor 2022-10-26 Inactive Yes 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2A receptor 7WC6 7wc6
OX1 receptor 2022-08-16 Inactive No OX1R OX1 Orexin A (Rhodopsin) Human - - ox1r_human
MCH2 receptor 2022-08-16 Active No MCHR2 MCH2 Melanin-concentrating hormone A (Rhodopsin) Human - - mchr2_human
D2 receptor 2022-08-16 Inactive No DRD2 D2 Dopamine A (Rhodopsin) Human - - drd2_human
MRGPRD 2023-06-14 Active Yes MRGRD MRGPRD A orphans A (Rhodopsin) Human MRGPRD 7Y13 7y13
GPR52 2022-08-16 Active No GPR52 GPR52 A orphans A (Rhodopsin) Human - - gpr52_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 6ZDR 6zdr
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5UVI 5uvi
ADGRA3 2022-08-16 Inactive No AGRA3 ADGRA3 ADGRA B2 (Adhesion) Human - - agra3_human
PTH1 receptor 2022-08-16 Active No PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human - - pth1r_human
δ receptor 2022-10-26 Inactive Yes OPRD δ Opioid A (Rhodopsin) Human δ receptor 4RWD 4rwd
NTS1 receptor 2022-10-26 Active Yes NTR1 NTS1 Neurotensin A (Rhodopsin) Rat NTS1 receptor 4GRV 4grv
CELSR2 2022-08-16 Active No CELR2 CELSR2 ADGRC B2 (Adhesion) Human - - celr2_human
GPR174 2022-08-16 Active No GP174 GPR174 A orphans A (Rhodopsin) Human - - gp174_human
μ receptor 2023-03-05 Inactive Yes OPRM μ Opioid A (Rhodopsin) Mouse μ receptor 7UL4 7ul4
A2B receptor 2022-08-16 Inactive No AA2BR A2B Adenosine A (Rhodopsin) Human - - aa2br_human
GPR52 2022-10-26 Inactive Yes GPR52 GPR52 A orphans A (Rhodopsin) Human GPR52 6LI0 6li0
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 6NWE 6nwe
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Human Rhodopsin 5W0P 5w0p
OX1 receptor 2022-10-26 Inactive Yes OX1R OX1 Orexin A (Rhodopsin) Human OX1 receptor 4ZJ8 4zj8
Olfactory receptor 51B2 2022-08-16 Active No O51B2 Olfactory 51B2 Olfactory A (Rhodopsin) Human - - o51b2_human
A2A receptor 2022-08-16 Inactive No AA2AR A2A Adenosine A (Rhodopsin) Human - - aa2ar_human
S1P1 receptor 2023-06-14 Inactive Yes S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human S1P1 receptor 3V2W 3v2w
β2-adrenoceptor 2022-10-26 Active Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 4LDE 4lde
SST4 receptor 2022-08-16 Active No SSR4 SST4 Somatostatin A (Rhodopsin) Human - - ssr4_human
ADGRA1 2022-08-16 Inactive No AGRA1 ADGRA1 ADGRA B2 (Adhesion) Human - - agra1_human
MC5 receptor 2022-08-16 Active No MC5R MC5 Melanocortin A (Rhodopsin) Human - - mc5r_human
TAS2R40 2022-08-16 Active No T2R40 TAS2R40 Taste 2 T (Taste 2) Human - - t2r40_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5OM1 5om1
mGlu1 receptor 2022-10-26 Inactive Yes GRM1 mGlu1 Metabotropic glutamate C (Glutamate) Human mGlu1 receptor 7DGD 7dgd
5-HT2B receptor 2022-10-26 Active Yes 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2B receptor 5TUD 5tud
succinate receptor 2022-10-26 Intermediate Yes SUCR1 succinate Succinate A (Rhodopsin) Rat succinate receptor 6Z10 6z10
mGlu2 receptor 2022-10-26 Inactive Yes GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human mGlu2 receptor 7EPF 7epf
CCR10 2022-08-16 Inactive No CCR10 CCR10 Chemokine A (Rhodopsin) Human - - ccr10_human
ADGRF4 2022-08-16 Inactive No AGRF4 ADGRF4 ADGRF B2 (Adhesion) Human - - agrf4_human
5-HT2A receptor 2022-10-26 Inactive Yes 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2A receptor 6A93 6a93
CaS receptor 2022-10-26 Active Yes CASR CaS Calcium-sensing C (Glutamate) Human CaS receptor 7SIM 7sim
CaS receptor 2022-10-26 Inactive Yes CASR CaS Calcium-sensing C (Glutamate) Human CaS receptor 7M3J 7m3j
PAC1 receptor 2022-08-16 Inactive No PACR PAC1 VIP and PACAP B1 (Secretin) Human - - pacr_human
GPR20 2023-06-12 Intermediate Yes GPR20 GPR20 A orphans A (Rhodopsin) Human GPR20 8HS2 8hs2
PAF receptor 2022-10-26 Other Yes PTAFR PAF Platelet-activating factor A (Rhodopsin) Human PAF receptor 5ZKP 5zkp
ADGRB1 2022-08-16 Inactive No AGRB1 ADGRB1 ADGRB B2 (Adhesion) Human - - agrb1_human
Rhodopsin 2022-08-16 Inactive No OPSD Rhodopsin Opsins A (Rhodopsin) Human - - opsd_human
α2B-adrenoceptor 2022-08-16 Active No ADA2B α2B Adrenoceptors A (Rhodopsin) Human - - ada2b_human
H2 receptor 2023-03-05 Inactive Yes HRH2 H2 Histamine A (Rhodopsin) Human H2 receptor 7UL3 7ul3
SST5 receptor 2022-08-16 Active No SSR5 SST5 Somatostatin A (Rhodopsin) Human - - ssr5_human
β3-adrenoceptor 2022-08-16 Active No ADRB3 β3 Adrenoceptors A (Rhodopsin) Human - - adrb3_human
β3-adrenoceptor 2022-08-16 Inactive No ADRB3 β3 Adrenoceptors A (Rhodopsin) Human - - adrb3_human
GPR18 2022-08-16 Active No GPR18 GPR18 GPR18, GPR55 and GPR119 A (Rhodopsin) Human - - gpr18_human
CX3CR1 2022-08-16 Active No CX3C1 CX3CR1 Chemokine A (Rhodopsin) Human - - cx3c1_human
5-HT1D receptor 2022-08-16 Active No 5HT1D 5-HT1D 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht1d_human
β1-adrenoceptor 2022-10-26 Inactive Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 5F8U 5f8u
HCA2 receptor 2022-08-16 Inactive No HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human - - hcar2_human
NK1 receptor 2022-10-26 Inactive Yes NK1R NK1 Tachykinin A (Rhodopsin) Human NK1 receptor 6HLP 6hlp
α2C-adrenoceptor 2022-10-26 Inactive Yes ADA2C α2C Adrenoceptors A (Rhodopsin) Human α2C-adrenoceptor 6KUW 6kuw
EP1 receptor 2022-08-16 Active No PE2R1 EP1 Prostanoid A (Rhodopsin) Human - - pe2r1_human
ACKR1 2022-08-16 Inactive No ACKR1 ACKR1 Chemokine A (Rhodopsin) Human - - ackr1_human
LH receptor 2022-08-16 Inactive No LSHR LH Glycoprotein hormone A (Rhodopsin) Human - - lshr_human
ACKR3 2023-06-14 Active Yes ACKR3 ACKR3 Chemokine A (Rhodopsin) Human ACKR3 7SK4 7sk4
OX1 receptor 2022-10-26 Inactive Yes OX1R OX1 Orexin A (Rhodopsin) Human OX1 receptor 4ZJC 4zjc
NTS1 receptor 2023-06-14 Intermediate Yes NTR1 NTS1 Neurotensin A (Rhodopsin) Rat NTS1 receptor 6Z66 6z66
A2B receptor 2022-08-16 Active No AA2BR A2B Adenosine A (Rhodopsin) Human - - aa2br_human
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 6PS3 6ps3
GPR37 2022-08-16 Active No GPR37 GPR37 A orphans A (Rhodopsin) Human - - gpr37_human
GPR35 2022-08-16 Active No GPR35 GPR35 A orphans A (Rhodopsin) Human - - gpr35_human
GPR62 2022-08-16 Active No GPR62 GPR62 A orphans A (Rhodopsin) Human - - gpr62_human
Rhodopsin 2022-10-26 Inactive Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 1U19 1u19
MT2 receptor 2022-10-26 Inactive Yes MTR1B MT2 Melatonin A (Rhodopsin) Human MT2 receptor 6ME6 6me6
BB2 receptor 2023-06-12 Inactive Yes GRPR BB2 Bombesin A (Rhodopsin) Human BB2 receptor 7W41 7w41
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5MZJ 5mzj
GAL2 receptor 2022-08-16 Inactive No GALR2 GAL2 Galanin A (Rhodopsin) Human - - galr2_human
TPRA1 2022-08-16 Active No TPRA1 TPRA1 Other GPCR orphans Other GPCRs Human - - tpra1_human
CT receptor 2022-08-16 Inactive No CALCR CT Calcitonin B1 (Secretin) Human - - calcr_human
GPR82 2022-08-16 Inactive No GPR82 GPR82 A orphans A (Rhodopsin) Human - - gpr82_human
TAAR9 2022-08-16 Inactive No TAAR9 TAAR9 A orphans A (Rhodopsin) Human - - taar9_human
NK1 receptor 2022-10-26 Inactive Yes NK1R NK1 Tachykinin A (Rhodopsin) Human NK1 receptor 6E59 6e59
M2 receptor 2022-10-26 Inactive Yes ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human M2 receptor 5YC8 5yc8
UT receptor 2022-08-16 Inactive No UR2R UT Urotensin A (Rhodopsin) Human - - ur2r_human
CELSR3 2022-08-16 Inactive No CELR3 CELSR3 ADGRC B2 (Adhesion) Human - - celr3_human
TAS2R31 2022-08-16 Inactive No T2R31 TAS2R31 Taste 2 T (Taste 2) Human - - t2r31_human
Olfactory receptor 51I1 2022-08-16 Inactive No O51I1 Olfactory 51I1 Olfactory A (Rhodopsin) Human - - o51i1_human
OX2 receptor 2022-10-26 Inactive Yes OX2R OX2 Orexin A (Rhodopsin) Human OX2 receptor 5WS3 5ws3
FZD3 2022-08-16 Active No FZD3 FZD3 Frizzled F (Frizzled) Human - - fzd3_human
GPR37 2022-08-16 Inactive No GPR37 GPR37 A orphans A (Rhodopsin) Human - - gpr37_human
TAS2R40 2022-08-16 Inactive No T2R40 TAS2R40 Taste 2 T (Taste 2) Human - - t2r40_human
Olfactory receptor 51A2 2022-08-16 Active No O51A2 Olfactory 51A2 Olfactory A (Rhodopsin) Human - - o51a2_human
NOP receptor 2022-10-26 Inactive Yes OPRX NOP Opioid A (Rhodopsin) Human NOP receptor 4EA3 4ea3
GPR139 2022-08-16 Inactive No GP139 GPR139 A orphans A (Rhodopsin) Human - - gp139_human
CXCR4 2022-10-26 Inactive Yes CXCR4 CXCR4 Chemokine A (Rhodopsin) Human CXCR4 3ODU 3odu
ETB receptor 2022-10-26 Inactive Yes EDNRB ETB Endothelin A (Rhodopsin) Human ETB receptor 6IGK 6igk
LGR5 2022-08-16 Inactive No LGR5 LGR5 A orphans A (Rhodopsin) Human - - lgr5_human
FPR1 2022-08-16 Active No FPR1 FPR1 Formylpeptide A (Rhodopsin) Human - - fpr1_human
DP2 receptor 2022-08-16 Active No PD2R2 DP2 Prostanoid A (Rhodopsin) Human - - pd2r2_human
P2RY10 2022-08-16 Active No P2Y10 P2RY10 A orphans A (Rhodopsin) Human - - p2y10_human
α2B-adrenoceptor 2022-08-16 Inactive No ADA2B α2B Adrenoceptors A (Rhodopsin) Human - - ada2b_human
FZD5 2022-08-16 Inactive No FZD5 FZD5 Frizzled F (Frizzled) Human - - fzd5_human
H1 receptor 2022-10-26 Inactive Yes HRH1 H1 Histamine A (Rhodopsin) Human H1 receptor 3RZE 3rze
D1 receptor 2022-08-16 Active No DRD1 D1 Dopamine A (Rhodopsin) Human - - drd1_human
Olfactory receptor 51A7 2022-08-16 Active No O51A7 Olfactory 51A7 Olfactory A (Rhodopsin) Human - - o51a7_human
Olfactory receptor 51E1 2022-08-16 Active No O51E1 Olfactory 51E1 Olfactory A (Rhodopsin) Human - - o51e1_human
mGlu3 receptor 2022-08-16 Inactive No GRM3 mGlu3 Metabotropic glutamate C (Glutamate) Human - - grm3_human
GPR15 2022-08-16 Inactive No GPR15 GPR15 A orphans A (Rhodopsin) Human - - gpr15_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 4J4Q 4j4q
QRFP receptor 2022-08-16 Inactive No QRFPR QRFP Peptide P518 A (Rhodopsin) Human - - qrfpr_human
TAS1R1 2022-08-16 Inactive No TS1R1 TAS1R1 Taste 1 C (Glutamate) Human - - ts1r1_human
PrRP receptor 2022-08-16 Active No PRLHR PrRP Prolactin-releasing peptide A (Rhodopsin) Human - - prlhr_human
GAL1 receptor 2022-08-16 Inactive No GALR1 GAL1 Galanin A (Rhodopsin) Human - - galr1_human
CysLT2 receptor 2022-10-26 Intermediate Yes CLTR2 CysLT2 Leukotriene A (Rhodopsin) Human CysLT2 receptor 6RZ6 6rz6
MAS1 2022-08-16 Inactive No MAS MAS1 A orphans A (Rhodopsin) Human - - mas_human
Olfactory receptor 51G2 2022-08-16 Active No O51G2 Olfactory 51G2 Olfactory A (Rhodopsin) Human - - o51g2_human
LPA5 receptor 2022-08-16 Inactive No LPAR5 LPA5 Lysophospholipid (LPA) A (Rhodopsin) Human - - lpar5_human
Olfactory receptor 51I1 2022-08-16 Active No O51I1 Olfactory 51I1 Olfactory A (Rhodopsin) Human - - o51i1_human
mGlu5 receptor 2023-06-27 Active Yes GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human mGlu5 receptor 7FD8 7fd8
LGR5 2022-08-16 Active No LGR5 LGR5 A orphans A (Rhodopsin) Human - - lgr5_human
ADGRG7 2022-08-16 Inactive No AGRG7 ADGRG7 ADGRG B2 (Adhesion) Human - - agrg7_human
M3 receptor 2022-10-26 Inactive Yes ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat M3 receptor 4U16 4u16
glucagon receptor 2022-08-16 Active No GLR glucagon Glucagon B1 (Secretin) Human - - glr_human
GPRC6 receptor 2022-08-16 Inactive No GPC6A GPRC6 C Orphans C (Glutamate) Human - - gpc6a_human
GPR146 2022-08-16 Active No GP146 GPR146 A orphans A (Rhodopsin) Human - - gp146_human
Rhodopsin 2022-10-26 Inactive Yes OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid Rhodopsin 2Z73 2z73
OPN1LW 2022-08-16 Active No OPSR OPN1LW Opsins A (Rhodopsin) Human - - opsr_human
LH receptor 2022-10-26 Inactive Yes LSHR LH Glycoprotein hormone A (Rhodopsin) Human LH receptor 7FIJ 7fij
TAS2R13 2022-08-16 Active No T2R13 TAS2R13 Taste 2 T (Taste 2) Human - - t2r13_human
H1 receptor 2022-08-16 Inactive No HRH1 H1 Histamine A (Rhodopsin) Human - - hrh1_human
LPA3 receptor 2022-08-16 Active No LPAR3 LPA3 Lysophospholipid (LPA) A (Rhodopsin) Human - - lpar3_human
C5a1 receptor 2022-10-26 Inactive Yes C5AR1 C5a1 Complement peptide A (Rhodopsin) Human C5a1 receptor 5O9H 5o9h
BB1 receptor 2022-08-16 Active No NMBR BB1 Bombesin A (Rhodopsin) Human - - nmbr_human
GPR88 2022-08-16 Inactive No GPR88 GPR88 A orphans A (Rhodopsin) Human - - gpr88_human
GPR182 2022-08-16 Inactive No GP182 GPR182 A orphans A (Rhodopsin) Human - - gp182_human
α2A-adrenoceptor 2022-10-26 Inactive Yes ADA2A α2A Adrenoceptors A (Rhodopsin) Human α2A-adrenoceptor 6KUX 6kux
5-HT2A receptor 2022-10-26 Inactive Yes 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2A receptor 7VOD 7vod
ACKR3 2022-08-16 Inactive No ACKR3 ACKR3 Chemokine A (Rhodopsin) Human - - ackr3_human
mGlu6 receptor 2022-08-16 Inactive No GRM6 mGlu6 Metabotropic glutamate C (Glutamate) Human - - grm6_human
OX2 receptor 2022-08-16 Active No OX2R OX2 Orexin A (Rhodopsin) Human - - ox2r_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 6JZH 6jzh
ADGRD2 2022-08-16 Active No AGRD2 ADGRD2 ADGRD B2 (Adhesion) Human - - agrd2_human
GPR146 2022-08-16 Inactive No GP146 GPR146 A orphans A (Rhodopsin) Human - - gp146_human
ACKR3 2023-03-05 Active Yes ACKR3 ACKR3 Chemokine A (Rhodopsin) Human ACKR3 7SK3 7sk3
TAS2R45 2022-08-16 Active No T2R45 TAS2R45 Taste 2 T (Taste 2) Human - - t2r45_human
GLP-1 receptor 2022-10-26 Inactive Yes GLP1R GLP-1 Glucagon B1 (Secretin) Human GLP-1 receptor 5VEW 5vew
A2A receptor 2022-10-26 Active Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 4UG2 4ug2
GPR17 2022-08-16 Inactive No GPR17 GPR17 A orphans A (Rhodopsin) Human - - gpr17_human
ADGRA2 2022-08-16 Active No AGRA2 ADGRA2 ADGRA B2 (Adhesion) Human - - agra2_human
HCA3 receptor 2022-08-16 Active No HCAR3 HCA3 Hydroxycarboxylic acid A (Rhodopsin) Human - - hcar3_human
SMO 2022-08-16 Inactive No SMO SMO Frizzled F (Frizzled) Human - - smo_human
Rhodopsin 2022-10-26 Inactive Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 6OFJ 6ofj
PAR1 2022-08-16 Inactive No PAR1 PAR1 Proteinase-activated A (Rhodopsin) Human - - par1_human
RXFP4 2022-08-16 Inactive No RL3R2 RXFP4 Relaxin family peptide A (Rhodopsin) Human - - rl3r2_human
NK1 receptor 2022-08-16 Inactive No NK1R NK1 Tachykinin A (Rhodopsin) Human - - nk1r_human
β1-adrenoceptor 2022-10-26 Active Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Human β1-adrenoceptor 7BU6 7bu6
MRGPRX3 2022-08-16 Active No MRGX3 MRGPRX3 A orphans A (Rhodopsin) Human - - mrgx3_human
Y2 receptor 2023-06-12 Active Yes NPY2R Y2 Neuropeptide Y A (Rhodopsin) Human Y2 receptor 7YOO 7yoo
P2Y2 receptor 2022-08-16 Active No P2RY2 P2Y2 P2Y A (Rhodopsin) Human - - p2ry2_human
5-HT7 receptor 2022-08-16 Active No 5HT7R 5-HT7 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht7r_human
P2Y13 receptor 2022-08-16 Inactive No P2Y13 P2Y13 P2Y A (Rhodopsin) Human - - p2y13_human
Rhodopsin 2022-10-26 Inactive Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 1GZM 1gzm
OPN4 2022-08-16 Active No OPN4 OPN4 Opsins A (Rhodopsin) Human - - opn4_human
FFA1 receptor 2022-10-26 Intermediate Yes FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human FFA1 receptor 5TZR 5tzr
GPR162 2022-08-16 Active No GP162 GPR162 A orphans A (Rhodopsin) Human - - gp162_human
NK1 receptor 2022-10-26 Inactive Yes NK1R NK1 Tachykinin A (Rhodopsin) Human NK1 receptor 6HLO 6hlo
CaS receptor 2022-08-16 Inactive No CASR CaS Calcium-sensing C (Glutamate) Human - - casr_human
FFA4 receptor 2022-08-16 Inactive No FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human - - ffar4_human
CXCR4 2023-06-14 Inactive Yes CXCR4 CXCR4 Chemokine A (Rhodopsin) Human CXCR4 3OE6 3oe6
GABAB2 2022-08-16 Inactive No GABR2 GABAB2 GABAB C (Glutamate) Human - - gabr2_human
Y2 receptor 2022-10-26 Inactive Yes NPY2R Y2 Neuropeptide Y A (Rhodopsin) Human Y2 receptor 7DDZ 7ddz
P2Y12 receptor 2022-10-26 Intermediate Yes P2Y12 P2Y12 P2Y A (Rhodopsin) Human P2Y12 receptor 4NTJ 4ntj
MRGPRX1 2022-08-16 Inactive No MRGX1 MRGPRX1 A orphans A (Rhodopsin) Human - - mrgx1_human
GPR37L1 2022-08-16 Inactive No G37L1 GPR37L1 A orphans A (Rhodopsin) Human - - g37l1_human
ADGRF2 2022-08-16 Inactive No AGRF2 ADGRF2 ADGRF B2 (Adhesion) Human - - agrf2_human
GPR143 2022-08-16 Inactive No GP143 GPR143 Other GPCR orphans Other GPCRs Human - - gp143_human
LGR6 2022-08-16 Active No LGR6 LGR6 A orphans A (Rhodopsin) Human - - lgr6_human
GPR107 2022-08-16 Active No GP107 GPR107 Other GPCR orphans Other GPCRs Human - - gp107_human
VPAC2 receptor 2022-08-16 Active No VIPR2 VPAC2 VIP and PACAP B1 (Secretin) Human - - vipr2_human
GPR183 2022-10-26 Intermediate Yes GP183 GPR183 A orphans A (Rhodopsin) Human GPR183 7TUY 7tuy
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 6PS0 6ps0
ADGRV1 2022-08-16 Inactive No AGRV1 ADGRV1 ADGRV B2 (Adhesion) Human - - agrv1_human
Y5 receptor 2022-08-16 Inactive No NPY5R Y5 Neuropeptide Y A (Rhodopsin) Human - - npy5r_human
ADGRL2 2022-08-16 Inactive No AGRL2 ADGRL2 ADGRL B2 (Adhesion) Human - - agrl2_human
EP3 receptor 2022-08-16 Active No PE2R3 EP3 Prostanoid A (Rhodopsin) Human - - pe2r3_human
ADGRB3 2022-08-16 Inactive No AGRB3 ADGRB3 ADGRB B2 (Adhesion) Human - - agrb3_human
ADGRB3 2022-08-16 Active No AGRB3 ADGRB3 ADGRB B2 (Adhesion) Human - - agrb3_human
CXCR3 2022-08-16 Inactive No CXCR3 CXCR3 Chemokine A (Rhodopsin) Human - - cxcr3_human
5-HT1F receptor 2022-08-16 Active No 5HT1F 5-HT1F 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht1f_human
M3 receptor 2023-03-05 Active Yes ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Human M3 receptor 8EA0 8ea0
CB1 receptor 2022-10-26 Active Yes CNR1 CB1 Cannabinoid A (Rhodopsin) Human CB1 receptor 5XRA 5xra
5-HT2C receptor 2022-08-16 Active No 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht2c_human
GPR32 2022-08-16 Active No GPR32 GPR32 A orphans A (Rhodopsin) Human - - gpr32_human
A2A receptor 2022-10-26 Active Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5G53 5g53
Olfactory receptor 51F2 2022-08-16 Active No O51F2 Olfactory 51F2 Olfactory A (Rhodopsin) Human - - o51f2_human
CysLT1 receptor 2022-08-16 Active No CLTR1 CysLT1 Leukotriene A (Rhodopsin) Human - - cltr1_human
OPN1SW 2022-08-16 Inactive No OPSB OPN1SW Opsins A (Rhodopsin) Human - - opsb_human
GPR158 2022-10-26 Inactive Yes GP158 GPR158 C Orphans C (Glutamate) Human GPR158 7EWL 7ewl
CB1 receptor 2022-10-26 Inactive Yes CNR1 CB1 Cannabinoid A (Rhodopsin) Human CB1 receptor 6KQI 6kqi
CB1 receptor 2022-10-26 Inactive Yes CNR1 CB1 Cannabinoid A (Rhodopsin) Human CB1 receptor 5TGZ 5tgz
ADGRG2 2022-08-16 Active No AGRG2 ADGRG2 ADGRG B2 (Adhesion) Human - - agrg2_human
NTS1 receptor 2022-08-16 Inactive No NTR1 NTS1 Neurotensin A (Rhodopsin) Human - - ntr1_human
mGlu5 receptor 2022-10-26 Inactive Yes GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human mGlu5 receptor 6N52 6n52
B2 receptor 2022-08-16 Active No BKRB2 B2 Bradykinin A (Rhodopsin) Human - - bkrb2_human
Olfactory receptor 51B5 2022-08-16 Active No O51B5 Olfactory 51B5 Olfactory A (Rhodopsin) Human - - o51b5_human
mGlu5 receptor 2022-08-16 Inactive No GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human - - grm5_human
GPER 2022-08-16 Active No GPER1 GPER Estrogen (G protein-coupled) A (Rhodopsin) Human - - gper1_human
5-HT1B receptor 2022-10-26 Inactive Yes 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT1B receptor 7C61 7c61
GPR27 2022-08-16 Active No GPR27 GPR27 A orphans A (Rhodopsin) Human - - gpr27_human
NK3 receptor 2022-08-16 Inactive No NK3R NK3 Tachykinin A (Rhodopsin) Human - - nk3r_human
β1-adrenoceptor 2022-08-16 Inactive No ADRB1 β1 Adrenoceptors A (Rhodopsin) Human - - adrb1_human
TAS2R4 2022-08-16 Inactive No TA2R4 TAS2R4 Taste 2 T (Taste 2) Human - - ta2r4_human
TAS2R8 2022-08-16 Active No TA2R8 TAS2R8 Taste 2 T (Taste 2) Human - - ta2r8_human
δ receptor 2022-08-16 Inactive No OPRD δ Opioid A (Rhodopsin) Human - - oprd_human
M1 receptor 2022-10-26 Inactive Yes ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human M1 receptor 6ZFZ 6zfz
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5OLV 5olv
GPR158 2022-10-26 Inactive Yes GP158 GPR158 C Orphans C (Glutamate) Human GPR158 7EWP 7ewp
CaS receptor 2023-06-14 Inactive Yes CASR CaS Calcium-sensing C (Glutamate) Human CaS receptor 7M3E 7m3e
β1-adrenoceptor 2022-10-26 Active Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 6TKO 6tko
ADGRB2 2022-08-16 Inactive No AGRB2 ADGRB2 ADGRB B2 (Adhesion) Human - - agrb2_human
5-HT1B receptor 2022-08-16 Active No 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht1b_human
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 3PDS 3pds
TA1 receptor 2022-08-16 Inactive No TAAR1 TA1 Trace amine A (Rhodopsin) Human - - taar1_human
kisspeptin receptor 2022-08-16 Inactive No KISSR kisspeptin Kisspeptin A (Rhodopsin) Human - - kissr_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5UIG 5uig
5-HT2A receptor 2022-10-26 Inactive Yes 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2A receptor 7VOE 7voe
GPR132 2022-08-16 Active No GP132 GPR132 A orphans A (Rhodopsin) Human - - gp132_human
PAR4 2022-08-16 Inactive No PAR4 PAR4 Proteinase-activated A (Rhodopsin) Human - - par4_human
GPR158 2022-08-16 Active No GP158 GPR158 C Orphans C (Glutamate) Human - - gp158_human
P2Y13 receptor 2022-08-16 Active No P2Y13 P2Y13 P2Y A (Rhodopsin) Human - - p2y13_human
FFA1 receptor 2022-08-16 Active No FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human - - ffar1_human
β2-adrenoceptor 2022-10-26 Active Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 6MXT 6mxt
5-HT6 receptor 2022-08-16 Inactive No 5HT6R 5-HT6 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht6r_human
EP2 receptor 2022-08-16 Active No PE2R2 EP2 Prostanoid A (Rhodopsin) Human - - pe2r2_human
NTS1 receptor 2022-08-16 Active No NTR1 NTS1 Neurotensin A (Rhodopsin) Human - - ntr1_human
GPR50 2022-08-16 Active No MTR1L GPR50 A orphans A (Rhodopsin) Human - - mtr1l_human
TAS2R41 2022-08-16 Active No T2R41 TAS2R41 Taste 2 T (Taste 2) Human - - t2r41_human
ADGRE4P 2022-08-16 Inactive No AGRE4 ADGRE4P ADGRE B2 (Adhesion) Human - - agre4_human
CXCR5 2022-08-16 Inactive No CXCR5 CXCR5 Chemokine A (Rhodopsin) Human - - cxcr5_human
GPR12 2022-08-16 Active No GPR12 GPR12 A orphans A (Rhodopsin) Human - - gpr12_human
S1P5 receptor 2022-08-16 Active No S1PR5 S1P5 Lysophospholipid (S1P) A (Rhodopsin) Human - - s1pr5_human
S1P2 receptor 2022-08-16 Inactive No S1PR2 S1P2 Lysophospholipid (S1P) A (Rhodopsin) Human - - s1pr2_human
A2A receptor 2023-03-05 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 8CU6 8cu6
GPR158 2022-10-26 Inactive Yes GP158 GPR158 C Orphans C (Glutamate) Human GPR158 7SHE 7she
PTH2 receptor 2022-08-16 Inactive No PTH2R PTH2 Parathyroid hormone B1 (Secretin) Human - - pth2r_human
GPBA receptor 2022-08-16 Active No GPBAR GPBA Bile acid A (Rhodopsin) Human - - gpbar_human
V1A receptor 2022-08-16 Inactive No V1AR V1A Vasopressin and oxytocin A (Rhodopsin) Human - - v1ar_human
succinate receptor 2022-08-16 Active No SUCR1 succinate Succinate A (Rhodopsin) Human - - sucr1_human
P2Y6 receptor 2022-08-16 Active No P2RY6 P2Y6 P2Y A (Rhodopsin) Human - - p2ry6_human
GnRH1 receptor 2022-10-26 Inactive Yes GNRHR GnRH1 Gonadotrophin-releasing hormone A (Rhodopsin) Human GnRH1 receptor 7BR3 7br3
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 3RFM 3rfm
S1P3 receptor 2022-08-16 Active No S1PR3 S1P3 Lysophospholipid (S1P) A (Rhodopsin) Human - - s1pr3_human
ACKR3 2023-03-05 Active Yes ACKR3 ACKR3 Chemokine A (Rhodopsin) Human ACKR3 7SK6 7sk6
CCRL2 2022-08-16 Inactive No CCRL2 CCRL2 Chemokine A (Rhodopsin) Human - - ccrl2_human
GPR183 2022-08-16 Inactive No GP183 GPR183 A orphans A (Rhodopsin) Human - - gp183_human
OPN3 2022-08-16 Active No OPN3 OPN3 Opsins A (Rhodopsin) Human - - opn3_human
NK2 receptor 2022-08-16 Active No NK2R NK2 Tachykinin A (Rhodopsin) Human - - nk2r_human
5-HT2C receptor 2022-10-26 Active Yes 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2C receptor 6BQG 6bqg
β1-adrenoceptor 2022-10-26 Inactive Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 3ZPQ 3zpq
TAS2R30 2022-08-16 Inactive No T2R30 TAS2R30 Taste 2 T (Taste 2) Human - - t2r30_human
GPR65 2022-08-16 Inactive No PSYR GPR65 A orphans A (Rhodopsin) Human - - psyr_human
P2Y14 receptor 2022-08-16 Inactive No P2Y14 P2Y14 P2Y A (Rhodopsin) Human - - p2y14_human
LPA4 receptor 2022-08-16 Inactive No LPAR4 LPA4 Lysophospholipid (LPA) A (Rhodopsin) Human - - lpar4_human
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 6PS1 6ps1
GPR21 2022-08-16 Active No GPR21 GPR21 A orphans A (Rhodopsin) Human - - gpr21_human
TAS2R39 2022-08-16 Active No T2R39 TAS2R39 Taste 2 T (Taste 2) Human - - t2r39_human
mGlu1 receptor 2022-08-16 Inactive No GRM1 mGlu1 Metabotropic glutamate C (Glutamate) Human - - grm1_human
GPR101 2022-08-16 Active No GP101 GPR101 A orphans A (Rhodopsin) Human - - gp101_human
β1-adrenoceptor 2022-10-26 Active Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 6H7J 6h7j
MRGPRE 2022-08-16 Active No MRGRE MRGPRE A orphans A (Rhodopsin) Human - - mrgre_human
TP receptor 2022-08-16 Active No TA2R TP Prostanoid A (Rhodopsin) Human - - ta2r_human
Olfactory receptor 51F1 2022-08-16 Active No O51F1 Olfactory 51F1 Olfactory A (Rhodopsin) Human - - o51f1_human
AT2 receptor 2022-10-26 Active Yes AGTR2 AT2 Angiotensin A (Rhodopsin) Human AT2 receptor 7JNI 7jni
calcitonin receptor-like receptor 2022-08-16 Active No CALRL calcitonin-like Calcitonin B1 (Secretin) Human - - calrl_human
GPR148 2022-08-16 Active No GP148 GPR148 A orphans A (Rhodopsin) Human - - gp148_human
GPR84 2022-08-16 Inactive No GPR84 GPR84 A orphans A (Rhodopsin) Human - - gpr84_human
TP receptor 2022-10-26 Intermediate Yes TA2R TP Prostanoid A (Rhodopsin) Human TP receptor 6IIV 6iiv
MRGPRE 2022-08-16 Inactive No MRGRE MRGPRE A orphans A (Rhodopsin) Human - - mrgre_human
Olfactory receptor 1G1 2022-08-16 Active No OR1G1 Olfactory 1G1 Olfactory A (Rhodopsin) Human - - or1g1_human
GPR15 2022-08-16 Active No GPR15 GPR15 A orphans A (Rhodopsin) Human - - gpr15_human
5-HT2A receptor 2022-10-26 Inactive Yes 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2A receptor 7WC5 7wc5
FFA3 receptor 2022-08-16 Inactive No FFAR3 FFA3 Free fatty acid A (Rhodopsin) Human - - ffar3_human
H2 receptor 2022-08-16 Inactive No HRH2 H2 Histamine A (Rhodopsin) Human - - hrh2_human
QRFP receptor 2022-08-16 Active No QRFPR QRFP Peptide P518 A (Rhodopsin) Human - - qrfpr_human
ADGRG2 2022-08-16 Inactive No AGRG2 ADGRG2 ADGRG B2 (Adhesion) Human - - agrg2_human
Olfactory receptor 51G2 2022-08-16 Inactive No O51G2 Olfactory 51G2 Olfactory A (Rhodopsin) Human - - o51g2_human
GPR182 2022-08-16 Active No GP182 GPR182 A orphans A (Rhodopsin) Human - - gp182_human
ghrelin receptor 2022-08-16 Active No GHSR ghrelin Ghrelin A (Rhodopsin) Human - - ghsr_human
GPR61 2022-08-16 Active No GPR61 GPR61 A orphans A (Rhodopsin) Human - - gpr61_human
OPN3 2022-08-16 Inactive No OPN3 OPN3 Opsins A (Rhodopsin) Human - - opn3_human
GPR25 2022-08-16 Inactive No GPR25 GPR25 A orphans A (Rhodopsin) Human - - gpr25_human
DP2 receptor 2022-10-26 Inactive Yes PD2R2 DP2 Prostanoid A (Rhodopsin) Human DP2 receptor 6D27 6d27
HCA2 receptor 2022-08-16 Active No HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human - - hcar2_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 7RM5 7rm5
ETB receptor 2022-10-26 Inactive Yes EDNRB ETB Endothelin A (Rhodopsin) Human ETB receptor 5GLH 5glh
TAS2R16 2022-08-16 Inactive No T2R16 TAS2R16 Taste 2 T (Taste 2) Human - - t2r16_human
PAF receptor 2022-10-26 Intermediate Yes PTAFR PAF Platelet-activating factor A (Rhodopsin) Human PAF receptor 5ZKQ 5zkq
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 4BEY 4bey
CRF2 receptor 2022-08-16 Inactive No CRFR2 CRF2 Corticotropin-releasing factor B1 (Secretin) Human - - crfr2_human
OX1 receptor 2022-08-16 Active No OX1R OX1 Orexin A (Rhodopsin) Human - - ox1r_human
P2Y2 receptor 2022-08-16 Inactive No P2RY2 P2Y2 P2Y A (Rhodopsin) Human - - p2ry2_human
TAAR6 2022-08-16 Inactive No TAAR6 TAAR6 A orphans A (Rhodopsin) Human - - taar6_human
SMO 2022-10-26 Inactive Yes SMO SMO Frizzled F (Frizzled) Human SMO 5L7I 5l7i
GPR37L1 2022-08-16 Active No G37L1 GPR37L1 A orphans A (Rhodopsin) Human - - g37l1_human
CELSR2 2022-08-16 Inactive No CELR2 CELSR2 ADGRC B2 (Adhesion) Human - - celr2_human
NPBW1 receptor 2022-08-16 Inactive No NPBW1 NPBW1 Neuropeptide W/neuropeptide B A (Rhodopsin) Human - - npbw1_human
5-HT5A receptor 2022-08-16 Active No 5HT5A 5-HT5A 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht5a_human
NPS receptor 2022-08-16 Inactive No NPSR1 NPS Neuropeptide S A (Rhodopsin) Human - - npsr1_human
MRGPRF 2022-08-16 Active No MRGRF MRGPRF A orphans A (Rhodopsin) Human - - mrgrf_human
Y2 receptor 2022-08-16 Inactive No NPY2R Y2 Neuropeptide Y A (Rhodopsin) Human - - npy2r_human
EP3 receptor 2022-10-26 Active Yes PE2R3 EP3 Prostanoid A (Rhodopsin) Human EP3 receptor 6AK3 6ak3
5-HT1A receptor 2022-08-16 Active No 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht1a_human
MT1 receptor 2022-08-16 Inactive No MTR1A MT1 Melatonin A (Rhodopsin) Human - - mtr1a_human
β1-adrenoceptor 2022-10-26 Active Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 6IBL 6ibl
GPR119 2022-08-16 Inactive No GP119 GPR119 GPR18, GPR55 and GPR119 A (Rhodopsin) Human - - gp119_human
β2-adrenoceptor 2023-06-14 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 2R4R 2r4r
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 5JQH 5jqh
GPRC5A 2022-08-16 Inactive No RAI3 GPRC5A C Orphans C (Glutamate) Human - - rai3_human
OX1 receptor 2022-10-26 Inactive Yes OX1R OX1 Orexin A (Rhodopsin) Human OX1 receptor 6TQ6 6tq6
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 3VG9 3vg9
CXCR2 2022-10-26 Inactive Yes CXCR2 CXCR2 Chemokine A (Rhodopsin) Human CXCR2 6LFL 6lfl
ADGRF5 2022-08-16 Active No AGRF5 ADGRF5 ADGRF B2 (Adhesion) Human - - agrf5_human
AT2 receptor 2022-10-26 Active Yes AGTR2 AT2 Angiotensin A (Rhodopsin) Human AT2 receptor 5UNH 5unh
P2Y12 receptor 2022-10-26 Intermediate Yes P2Y12 P2Y12 P2Y A (Rhodopsin) Human P2Y12 receptor 4PY0 4py0
GPRC5B 2022-08-16 Inactive No GPC5B GPRC5B C Orphans C (Glutamate) Human - - gpc5b_human
ETB receptor 2022-10-26 Inactive Yes EDNRB ETB Endothelin A (Rhodopsin) Human ETB receptor 6K1Q 6k1q
mGlu7 receptor 2022-08-16 Active No GRM7 mGlu7 Metabotropic glutamate C (Glutamate) Human - - grm7_human
FSH receptor 2022-08-16 Active No FSHR FSH Glycoprotein hormone A (Rhodopsin) Human - - fshr_human
β1-adrenoceptor 2022-10-26 Inactive Yes ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey β1-adrenoceptor 5A8E 5a8e
LH receptor 2022-08-16 Active No LSHR LH Glycoprotein hormone A (Rhodopsin) Human - - lshr_human
D5 receptor 2022-08-16 Active No DRD5 D5 Dopamine A (Rhodopsin) Human - - drd5_human
PKR2 2022-08-16 Inactive No PKR2 PKR2 Prokineticin A (Rhodopsin) Human - - pkr2_human
CCR10 2022-08-16 Active No CCR10 CCR10 Chemokine A (Rhodopsin) Human - - ccr10_human
5-HT1B receptor 2022-08-16 Inactive No 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht1b_human
V2 receptor 2022-08-16 Active No V2R V2 Vasopressin and oxytocin A (Rhodopsin) Human - - v2r_human
apelin receptor 2022-10-26 Inactive Yes APJ apelin Apelin A (Rhodopsin) Human apelin receptor 6KNM 6knm
mGlu6 receptor 2022-08-16 Active No GRM6 mGlu6 Metabotropic glutamate C (Glutamate) Human - - grm6_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5IU4 5iu4
5-HT1A receptor 2022-08-16 Inactive No 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human - - 5ht1a_human
GPR26 2022-08-16 Inactive No GPR26 GPR26 A orphans A (Rhodopsin) Human - - gpr26_human
Olfactory receptor 51T1 2022-08-16 Inactive No O51T1 Olfactory 51T1 Olfactory A (Rhodopsin) Human - - o51t1_human
chemerin receptor 2 2022-08-16 Active No CML2 chemerin 2 Chemerin receptor A (Rhodopsin) Human - - cml2_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5OM4 5om4
PKR1 2022-08-16 Active No PKR1 PKR1 Prokineticin A (Rhodopsin) Human - - pkr1_human
GPR33 2022-08-16 Active No GPR33 GPR33 A orphans A (Rhodopsin) Human - - gpr33_human
mGlu4 receptor 2022-08-16 Inactive No GRM4 mGlu4 Metabotropic glutamate C (Glutamate) Human - - grm4_human
α1B-adrenoceptor 2022-08-16 Active No ADA1B α1B Adrenoceptors A (Rhodopsin) Human - - ada1b_human
ACKR4 2022-08-16 Inactive No ACKR4 ACKR4 Chemokine A (Rhodopsin) Human - - ackr4_human
β2-adrenoceptor 2022-08-16 Active No ADRB2 β2 Adrenoceptors A (Rhodopsin) Human - - adrb2_human
Rhodopsin 2023-06-12 Inactive Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 7ZBE 7zbe
FZD4 2022-10-26 Inactive Yes FZD4 FZD4 Frizzled F (Frizzled) Human FZD4 6BD4 6bd4
mGlu7 receptor 2022-08-16 Inactive No GRM7 mGlu7 Metabotropic glutamate C (Glutamate) Human - - grm7_human
LGR4 2022-08-16 Active No LGR4 LGR4 A orphans A (Rhodopsin) Human - - lgr4_human
P2Y6 receptor 2022-08-16 Inactive No P2RY6 P2Y6 P2Y A (Rhodopsin) Human - - p2ry6_human
α1D-adrenoceptor 2022-08-16 Inactive No ADA1D α1D Adrenoceptors A (Rhodopsin) Human - - ada1d_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Human Rhodopsin 4ZWJ 4zwj
5-HT2B receptor 2022-10-26 Intermediate Yes 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2B receptor 6DRX 6drx
PAF receptor 2022-08-16 Inactive No PTAFR PAF Platelet-activating factor A (Rhodopsin) Human - - ptafr_human
CCR2 2022-10-26 Inactive Yes CCR2 CCR2 Chemokine A (Rhodopsin) Human CCR2 6GPS 6gps
D3 receptor 2022-08-16 Inactive No DRD3 D3 Dopamine A (Rhodopsin) Human - - drd3_human
TSH receptor 2022-08-16 Active No TSHR TSH Glycoprotein hormone A (Rhodopsin) Human - - tshr_human
OX2 receptor 2022-08-16 Inactive No OX2R OX2 Orexin A (Rhodopsin) Human - - ox2r_human
GPR3 2022-08-16 Active No GPR3 GPR3 A orphans A (Rhodopsin) Human - - gpr3_human
HCA3 receptor 2022-08-16 Inactive No HCAR3 HCA3 Hydroxycarboxylic acid A (Rhodopsin) Human - - hcar3_human
CysLT2 receptor 2022-08-16 Active No CLTR2 CysLT2 Leukotriene A (Rhodopsin) Human - - cltr2_human
SST3 receptor 2022-08-16 Active No SSR3 SST3 Somatostatin A (Rhodopsin) Human - - ssr3_human
NTS1 receptor 2023-06-14 Inactive Yes NTR1 NTS1 Neurotensin A (Rhodopsin) Rat NTS1 receptor 4BV0 4bv0
mGlu5 receptor 2022-10-26 Inactive Yes GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human mGlu5 receptor 5CGD 5cgd
GPR176 2022-08-16 Inactive No GP176 GPR176 A orphans A (Rhodopsin) Human - - gp176_human
β2-adrenoceptor 2022-10-26 Active Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 6E67 6e67
kisspeptin receptor 2022-08-16 Active No KISSR kisspeptin Kisspeptin A (Rhodopsin) Human - - kissr_human
MT1 receptor 2022-10-26 Inactive Yes MTR1A MT1 Melatonin A (Rhodopsin) Human MT1 receptor 6ME5 6me5
BB1 receptor 2022-08-16 Inactive No NMBR BB1 Bombesin A (Rhodopsin) Human - - nmbr_human
CXCR2 2022-08-16 Active No CXCR2 CXCR2 Chemokine A (Rhodopsin) Human - - cxcr2_human
P2Y11 receptor 2022-08-16 Active No P2Y11 P2Y11 P2Y A (Rhodopsin) Human - - p2y11_human
M2 receptor 2022-08-16 Inactive No ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human - - acm2_human
GPR183 2022-08-16 Active No GP183 GPR183 A orphans A (Rhodopsin) Human - - gp183_human
ADGRL1 2022-08-16 Inactive No AGRL1 ADGRL1 ADGRL B2 (Adhesion) Human - - agrl1_human
CaS receptor 2022-10-26 Inactive Yes CASR CaS Calcium-sensing C (Glutamate) Human CaS receptor 7DTW 7dtw
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 5X7D 5x7d
NTS2 receptor 2022-08-16 Inactive No NTR2 NTS2 Neurotensin A (Rhodopsin) Human - - ntr2_human
FZD7 2022-08-16 Inactive No FZD7 FZD7 Frizzled F (Frizzled) Human - - fzd7_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 6PEL 6pel
ADGRG7 2022-08-16 Active No AGRG7 ADGRG7 ADGRG B2 (Adhesion) Human - - agrg7_human
MRGPRD 2022-08-16 Inactive No MRGRD MRGPRD A orphans A (Rhodopsin) Human - - mrgrd_human
C5a1 receptor 2022-10-26 Inactive Yes C5AR1 C5a1 Complement peptide A (Rhodopsin) Human C5a1 receptor 6C1Q 6c1q
MRGPRD 2023-03-05 Active Yes MRGRD MRGPRD A orphans A (Rhodopsin) Human MRGPRD 7Y14 7y14
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 6PH7 6ph7
CCK1 receptor 2022-08-16 Inactive No CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human - - cckar_human
TAS2R16 2022-08-16 Active No T2R16 TAS2R16 Taste 2 T (Taste 2) Human - - t2r16_human
S1P3 receptor 2022-10-26 Active Yes S1PR3 S1P3 Lysophospholipid (S1P) A (Rhodopsin) Human S1P3 receptor 7C4S 7c4s
V2 receptor 2022-08-16 Inactive No V2R V2 Vasopressin and oxytocin A (Rhodopsin) Human - - v2r_human
AT1 receptor 2022-10-26 Inactive Yes AGTR1 AT1 Angiotensin A (Rhodopsin) Human AT1 receptor 4ZUD 4zud
GPR55 2022-08-16 Active No GPR55 GPR55 GPR18, GPR55 and GPR119 A (Rhodopsin) Human - - gpr55_human
GPRC5C 2022-08-16 Inactive No GPC5C GPRC5C C Orphans C (Glutamate) Human - - gpc5c_human
5-HT2B receptor 2023-03-05 Intermediate Yes 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2B receptor 7SRQ 7srq
CB1 receptor 2022-08-16 Inactive No CNR1 CB1 Cannabinoid A (Rhodopsin) Human - - cnr1_human
LGR6 2022-08-16 Inactive No LGR6 LGR6 A orphans A (Rhodopsin) Human - - lgr6_human
Rhodopsin 2022-10-26 Active Yes OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Rhodopsin 6FUF 6fuf
P2Y12 receptor 2022-10-26 Intermediate Yes P2Y12 P2Y12 P2Y A (Rhodopsin) Human P2Y12 receptor 4PXZ 4pxz
GPR68 2022-08-16 Inactive No OGR1 GPR68 A orphans A (Rhodopsin) Human - - ogr1_human
GPR12 2022-08-16 Inactive No GPR12 GPR12 A orphans A (Rhodopsin) Human - - gpr12_human
A2A receptor 2022-10-26 Inactive Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 6LPJ 6lpj
5-HT2B receptor 2022-10-26 Intermediate Yes 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human 5-HT2B receptor 6DRY 6dry
GLP-1 receptor 2022-10-26 Active Yes GLP1R GLP-1 Glucagon B1 (Secretin) Human GLP-1 receptor 7LCJ 7lcj
TSH receptor 2023-06-14 Inactive Yes TSHR TSH Glycoprotein hormone A (Rhodopsin) Human TSH receptor 7XW7 7xw7
TAS2R14 2022-08-16 Inactive No T2R14 TAS2R14 Taste 2 T (Taste 2) Human - - t2r14_human
μ receptor 2022-10-26 Inactive Yes OPRM μ Opioid A (Rhodopsin) Mouse μ receptor 4DKL 4dkl
ADGRG5 2022-08-16 Inactive No AGRG5 ADGRG5 ADGRG B2 (Adhesion) Human - - agrg5_human
TAS1R3 2022-08-16 Inactive No TS1R3 TAS1R3 Taste 1 C (Glutamate) Human - - ts1r3_human
A2A receptor 2022-10-26 Active Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 5WF5 5wf5
GPR45 2022-08-16 Inactive No GPR45 GPR45 A orphans A (Rhodopsin) Human - - gpr45_human
H3 receptor 2022-08-16 Inactive No HRH3 H3 Histamine A (Rhodopsin) Human - - hrh3_human
β2-adrenoceptor 2022-10-26 Inactive Yes ADRB2 β2 Adrenoceptors A (Rhodopsin) Human β2-adrenoceptor 6PS4 6ps4
α1B-adrenoceptor 2022-08-16 Inactive No ADA1B α1B Adrenoceptors A (Rhodopsin) Human - - ada1b_human
Rhodopsin 2022-08-16 Active No OPSD Rhodopsin Opsins A (Rhodopsin) Human - - opsd_human
P2Y4 receptor 2022-08-16 Inactive No P2RY4 P2Y4 P2Y A (Rhodopsin) Human - - p2ry4_human
MAS1 2022-08-16 Active No MAS MAS1 A orphans A (Rhodopsin) Human - - mas_human
TAS2R42 2022-08-16 Active No T2R42 TAS2R42 Taste 2 T (Taste 2) Human - - t2r42_human
A2A receptor 2022-10-26 Active Yes AA2AR A2A Adenosine A (Rhodopsin) Human A2A receptor 2YDV 2ydv
Y4 receptor 2022-08-16 Active No NPY4R Y4 Neuropeptide Y A (Rhodopsin) Human - - npy4r_human
FZD2 2022-08-16 Inactive No FZD2 FZD2 Frizzled F (Frizzled) Human - - fzd2_human
CCR2 2022-08-16 Inactive No CCR2 CCR2 Chemokine A (Rhodopsin) Human - - ccr2_human
calcitonin receptor-like receptor 2022-10-26 Inactive Yes CALRL calcitonin-like Calcitonin B1 (Secretin) Human calcitonin receptor-like receptor 7KNT 7knt
ETB receptor 2022-10-26 Inactive Yes EDNRB ETB Endothelin A (Rhodopsin) Human ETB receptor 5X93 5x93
S1P4 receptor 2022-08-16 Inactive No S1PR4 S1P4 Lysophospholipid (S1P) A (Rhodopsin) Human - - s1pr4_human
GIP receptor 2022-08-16 Active No GIPR GIP Glucagon B1 (Secretin) Human - - gipr_human
δ receptor 2022-10-26 Active Yes OPRD δ Opioid A (Rhodopsin) Human δ receptor 6PT2 6pt2
M3 receptor 2022-10-26 Inactive Yes ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat M3 receptor 4U14 4u14
GPER 2022-08-16 Inactive No GPER1 GPER Estrogen (G protein-coupled) A (Rhodopsin) Human - - gper1_human
CELSR1 2022-08-16 Inactive No CELR1 CELSR1 ADGRC B2 (Adhesion) Human - - celr1_human
CB1 receptor 2023-03-05 Inactive Yes CNR1 CB1 Cannabinoid A (Rhodopsin) Human CB1 receptor 7FEE 7fee
CaS receptor 2022-08-16 Active No CASR CaS Calcium-sensing C (Glutamate) Human - - casr_human
CELSR1 2022-08-16 Active No CELR1 CELSR1 ADGRC B2 (Adhesion) Human - - celr1_human
GPRC5D 2022-08-16 Inactive No GPC5D GPRC5D C Orphans C (Glutamate) Human - - gpc5d_human
LPA6 receptor 2022-08-16 Inactive No LPAR6 LPA6 Lysophospholipid (LPA) A (Rhodopsin) Human - - lpar6_human
α1A-adrenoceptor 2022-08-16 Inactive No ADA1A α1A Adrenoceptors A (Rhodopsin) Human - - ada1a_human
GPRC6 receptor