ACKR3 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

ACKR3

SPECIES

Homo sapiens

STATE

Active

VERSION

2021-01-08

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

NGL is a WebGL based 3D viewer powered by MMTF.

MAIN TEMPLATE

CXCR2 (sequence similarity: 53%) PDB: 6LFO
Align

TEMPLATES

6LFO (CXCR2)
6LFL (CXCR2)
4ZUD (AT1 receptor)
5UIW (CCR5)
3ODU (CXCR4)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 84.8 5.9 9.2
Side-chains 29.4 52.1 18.5

Number of backbone templates: 5
Number of rotamer templates: 47

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 36 N CXCR2 6LFO CXCR2 6LFO
N-term 37 M CXCR2 6LFO CXCR2 6LFO
N-term 38 P CXCR2 6LFO CXCR2 6LFO
N-term 39 N CXCR2 6LFO CXCR2 6LFO
N-term 40 K CXCR2 6LFO CXCR2 6LFO
TM1 41 S 1.29x29 CXCR2 6LFO PAR1 3VW7
TM1 42 V 1.30x30 CXCR2 6LFO FPR2/ALX 6LW5
TM1 43 L 1.31x31 CXCR2 6LFO FPR2/ALX 6LW5
TM1 44 L 1.32x32 CXCR2 6LFO ghrelin receptor 6KO5
TM1 45 Y 1.33x33 CXCR2 6LFO CXCR2 6LFO
TM1 46 T 1.34x34 CXCR2 6LFO μ receptor 5C1M
TM1 47 L 1.35x35 CXCR2 6LFO Rhodopsin 4ZWJ
TM1 48 S 1.36x36 CXCR2 6LFO LPA6 receptor 5XSZ
TM1 49 F 1.37x37 CXCR2 6LFO US28 5WB1
TM1 50 I 1.38x38 CXCR2 6LFO CXCR2 6LFO
TM1 51 Y 1.39x39 CXCR2 6LFO CXCR2 6LFO
TM1 52 I 1.40x40 CXCR2 6LFO EP3 receptor 6M9T
TM1 53 F 1.41x41 CXCR2 6LFO α2B-adrenoceptor 6K41
TM1 54 I 1.42x42 CXCR2 6LFO AT1 receptor 6OS2
TM1 55 F 1.43x43 CXCR2 6LFO CXCR2 6LFO
TM1 56 V 1.44x44 CXCR2 6LFO AT1 receptor 6OS2
TM1 57 I 1.45x45 CXCR2 6LFO AT2 receptor 6JOD
TM1 58 G 1.46x46 CXCR2 6LFO AT1 receptor 6OS2
TM1 59 M 1.47x47 CXCR2 6LFO succinate receptor 6RNK
TM1 60 I 1.48x48 CXCR2 6LFO US28 5WB1
TM1 61 A 1.49x49 CXCR2 6LFO GPBA receptor 7CFN
TM1 62 N 1.50x50 CXCR2 6LFO CXCR2 6LFO
TM1 63 S 1.51x51 CXCR2 6LFO CXCR2 6LFO
TM1 64 V 1.52x52 CXCR2 6LFO AT2 receptor 6JOD
TM1 65 V 1.53x53 CXCR2 6LFO CXCR2 6LFO
TM1 66 V 1.54x54 CXCR2 6LFO AT1 receptor 6OS2
TM1 67 W 1.55x55 CXCR2 6LFO FPR2/ALX 6LW5
TM1 68 V 1.56x56 CXCR2 6LFO CXCR2 6LFO
TM1 69 N 1.57x57 CXCR2 6LFO - -
TM1 70 I 1.58x58 CXCR2 6LFO κ receptor 6B73
TM1 71 Q 1.59x59 CXCR2 6LFO Rhodopsin 4ZWJ
TM1 72 A 1.60x60 AT1 receptor 4ZUD TP receptor 6IIV
ICL1 73 K 12.48x48 - - - -
ICL1 74 T 12.49x49 AT1 receptor 4ZUD - -
ICL1 75 T 12.50x50 AT1 receptor 4ZUD - -
ICL1 76 G 12.51x51 - - - -
TM2 77 Y 2.37x37 CXCR2 6LFL 5-HT2B receptor 5TUD
TM2 78 D 2.38x38 CXCR2 6LFO - -
TM2 79 T 2.39x39 CXCR2 6LFO CXCR2 6LFO
TM2 80 H 2.40x40 CXCR2 6LFO NTS1 receptor 6OSA
TM2 81 C 2.41x41 CXCR2 6LFO A1 receptor 6D9H
TM2 82 Y 2.42x42 CXCR2 6LFO CXCR2 6LFO
TM2 83 I 2.43x43 CXCR2 6LFO κ receptor 6B73
TM2 84 L 2.44x44 CXCR2 6LFO CXCR2 6LFO
TM2 85 N 2.45x45 CXCR2 6LFO CXCR2 6LFO
TM2 86 L 2.46x46 CXCR2 6LFO CXCR2 6LFO
TM2 87 A 2.47x47 CXCR2 6LFO CXCR2 6LFO
TM2 88 I 2.48x48 CXCR2 6LFO CCR6 6WWZ
TM2 89 A 2.49x49 CXCR2 6LFO CXCR2 6LFO
TM2 90 D 2.50x50 CXCR2 6LFO CXCR2 6LFO
TM2 91 L 2.51x51 CXCR2 6LFO CXCR2 6LFO
TM2 92 W 2.52x52 CXCR2 6LFO - -
TM2 93 V 2.53x53 CXCR2 6LFO κ receptor 6B73
TM2 94 V 2.54x54 CXCR2 6LFO CCR6 6WWZ
TM2 95 L 2.55x55 CXCR2 6LFO CXCR2 6LFO
TM2 96 T 2.56x56 CXCR2 6LFO CXCR2 6LFO
TM2 97 I 2.57x57 CXCR2 6LFO α2B-adrenoceptor 6K41
TM2 98 P 2.58x58 CXCR2 6LFO CXCR2 6LFO
TM2 99 V 2.59x59 CXCR2 6LFO NTS1 receptor 6OSA
TM2 100 W 2.60x60 CXCR2 6LFO CXCR2 6LFO
TM2 101 V 2.61x61 CXCR2 6LFO D2 receptor 6VMS
TM2 102 V 2.62x62 CXCR2 6LFO AT1 receptor 6OS2
TM2 103 S 2.63x63 CXCR2 6LFO CXCR2 6LFO
TM2 104 L 2.64x64 CXCR2 6LFO US28 5WB1
TM2 105 V 2.65x65 CXCR2 6LFO CXCR2 6LFO
TM2 106 Q 2.66x66 CXCR2 6LFO C5a1 receptor 5O9H
ECL1 107 H - - - -
ECL1 108 N - - - -
ECL1 109 Q 23.49x49 CXCR2 6LFL CCR5 5UIW
ECL1 110 W 23.50x50 CXCR2 6LFL CXCR2 6LFL
ECL1 111 P 23.51x51 CXCR2 6LFL AT1 receptor 6OS2
ECL1 112 M 23.52x52 - - - -
TM3 113 G 3.21x21 CXCR2 6LFL CXCR2 6LFL
TM3 114 E 3.22x22 CXCR2 6LFO δ receptor 6PT2
TM3 115 L 3.23x23 CXCR2 6LFO δ receptor 6PT2
TM3 116 T 3.24x24 CXCR2 6LFO CCR6 6WWZ
TM3 117 C 3.25x25 CXCR2 6LFO CXCR2 6LFO
TM3 118 K 3.26x26 CXCR2 6LFO AT1 receptor 6OS2
TM3 119 V 3.27x27 CXCR2 6LFO CXCR2 6LFO
TM3 120 T 3.28x28 CXCR2 6LFO P2Y12 receptor 4NTJ
TM3 121 H 3.29x29 CXCR2 6LFO FPR2/ALX 6LW5
TM3 122 L 3.30x30 CXCR2 6LFO CXCR2 6LFO
TM3 123 I 3.31x31 CXCR2 6LFO CCR6 6WWZ
TM3 124 F 3.32x32 CXCR2 6LFO US28 5WB1
TM3 125 S 3.33x33 CXCR2 6LFO AT1 receptor 6OS2
TM3 126 I 3.34x34 CXCR2 6LFO CCR6 6WWZ
TM3 127 N 3.35x35 CXCR2 6LFO CXCR2 6LFO
TM3 128 L 3.36x36 CXCR2 6LFO AT1 receptor 6OS2
TM3 129 F 3.37x37 CXCR2 6LFO US28 5WB1
TM3 130 G 3.38x38 CXCR2 6LFO FPR2/ALX 6LW5
TM3 131 S 3.39x39 CXCR2 6LFO AT1 receptor 6OS2
TM3 132 I 3.40x40 CXCR2 6LFO CXCR2 6LFO
TM3 133 F 3.41x41 CXCR2 6LFO AT1 receptor 6OS2
TM3 134 F 3.42x42 CXCR2 6LFO US28 5WB1
TM3 135 L 3.43x43 CXCR2 6LFO CXCR2 6LFO
TM3 136 T 3.44x44 CXCR2 6LFO AT1 receptor 6OS2
TM3 137 C 3.45x45 CXCR2 6LFO CXCR2 6LFO
TM3 138 M 3.46x46 CXCR2 6LFO κ receptor 6B73
TM3 139 S 3.47x47 CXCR2 6LFO CXCR2 6LFO
TM3 140 V 3.48x48 CXCR2 6LFO CXCR2 6LFO
TM3 141 D 3.49x49 CXCR2 6LFO CXCR2 6LFO
TM3 142 R 3.50x50 CXCR2 6LFO CXCR2 6LFO
TM3 143 Y 3.51x51 CXCR2 6LFO CXCR2 6LFO
TM3 144 L 3.52x52 CXCR2 6LFO CXCR2 6LFO
TM3 145 S 3.53x53 CXCR2 6LFO AT2 receptor 6JOD
TM3 146 I 3.54x54 CXCR2 6LFO CXCR2 6LFO
TM3 147 T 3.55x55 CXCR2 6LFO M2 receptor 4MQT
TM3 148 Y 3.56x56 CXCR2 6LFO AT2 receptor 6JOD
ICL2 149 F - - - -
ICL2 150 T - - - -
ICL2 151 N - - - -
ICL2 152 T - - - -
ICL2 153 P - - - -
ICL2 154 S - - - -
ICL2 155 S - - - -
ICL2 156 R - - - -
ICL2 157 K - - - -
ICL2 158 K - - - -
ICL2 159 M - - - -
TM4 160 V 4.41x41 CXCR2 6LFO AT1 receptor 6OS2
TM4 161 R 4.42x42 CXCR2 6LFO - -
TM4 162 R 4.43x43 CXCR2 6LFO β2-adrenoceptor 3SN6
TM4 163 V 4.44x44 CXCR2 6LFO AT1 receptor 6OS2
TM4 164 V 4.45x45 CXCR2 6LFO FPR2/ALX 6LW5
TM4 165 C 4.46x46 CXCR2 6LFO CXCR2 6LFO
TM4 166 I 4.47x47 CXCR2 6LFO AT1 receptor 6OS2
TM4 167 L 4.48x48 CXCR2 6LFO AT2 receptor 6JOD
TM4 168 V 4.49x49 CXCR2 6LFO CCR6 6WWZ
TM4 169 W 4.50x50 CXCR2 6LFO CXCR2 6LFO
TM4 170 L 4.51x51 CXCR2 6LFO AT1 receptor 6OS2
TM4 171 L 4.52x52 CXCR2 6LFO CXCR2 6LFO
TM4 172 A 4.53x53 CXCR2 6LFO AT1 receptor 6OS2
TM4 173 F 4.54x54 CXCR2 6LFO M2 receptor 4MQT
TM4 174 C 4.55x55 CXCR2 6LFO ghrelin receptor 6KO5
TM4 175 V 4.56x56 CXCR2 6LFO κ receptor 6B73
TM4 176 S 4.57x57 CXCR2 6LFO AT1 receptor 6OS2
TM4 177 L 4.58x59 CXCR2 6LFO CXCR2 6LFO
TM4 178 P 4.59x60 CXCR2 6LFO CXCR2 6LFO
TM4 179 D 4.60x61 CXCR2 6LFO CXCR4 3ODU
TM4 180 T 4.61x62 CXCR2 6LFO - -
TM4 181 Y 4.62x63 CXCR2 6LFO AT2 receptor 6JOD
TM4 182 Y 4.63x64 CXCR2 6LFL CCR7 6QZH
TM4 183 L 4.64x65 CXCR2 6LFL FPR2/ALX 6LW5
ECL2 184 K CXCR2 6LFO - -
ECL2 185 T CXCR2 6LFO CXCR2 6LFO
ECL2 186 V CXCR2 6LFO CXCR2 6LFO
ECL2 187 T CXCR2 6LFO - -
ECL2 188 S CXCR2 6LFO CXCR2 6LFO
ECL2 189 A CXCR2 6LFO - -
ECL2 190 S CXCR2 6LFO - -
ECL2 191 N CXCR2 6LFO - -
ECL2 192 N CXCR2 6LFO - -
ECL2 193 E CXCR2 6LFO - -
ECL2 194 T CXCR2 6LFO - -
ECL2 195 Y - - - -
ECL2 196 C 45.50x50 CXCR2 6LFO CXCR2 6LFO
ECL2 197 R 45.51x51 CXCR2 6LFO ghrelin receptor 6KO5
ECL2 198 S 45.52x52 CXCR2 6LFO CCR5 5UIW
ECL2 199 F - - - -
ECL2 200 Y CCR5 5UIW CCR5 5UIW
ECL2 201 P CCR5 5UIW - -
ECL2 202 E CCR5 5UIW CCR5 5UIW
ECL2 203 H - - - -
TM5 204 S 5.30x31 CXCR2 6LFO apelin receptor 5VBL
TM5 205 I 5.31x32 CXCR2 6LFO - -
TM5 206 K 5.32x33 CXCR2 6LFO C5a1 receptor 5O9H
TM5 207 E 5.33x34 CXCR2 6LFO - -
TM5 208 W 5.34x35 CXCR2 6LFO CXCR2 6LFO
TM5 209 L 5.35x36 CXCR2 6LFO FPR2/ALX 6LW5
TM5 210 I 5.36x37 CXCR2 6LFO US28 5WB1
TM5 211 G 5.37x38 CXCR2 6LFO AT1 receptor 6OS0
TM5 212 M 5.38x39 CXCR2 6LFO CCR6 6WWZ
TM5 213 E 5.39x40 CXCR2 6LFO - -
TM5 214 L 5.40x41 CXCR2 6LFO AT1 receptor 6OS2
TM5 215 V 5.41x42 CXCR2 6LFO NTS1 receptor 6OSA
TM5 216 S 5.42x43 CXCR2 6LFO D2 receptor 6VMS
TM5 217 V 5.43x44 CXCR2 6LFO GPBA receptor 7CFN
TM5 218 V 5.44x45 CXCR2 6LFO FPR2/ALX 6LW5
TM5 219 L 5.45x46 CXCR2 6LFO AT1 receptor 6OS2
TM5 220 G 5.46x461 CXCR2 6LFO CXCR2 6LFO
TM5 221 F 5.47x47 CXCR2 6LFO CXCR2 6LFO
TM5 222 A 5.48x48 CXCR2 6LFO CB2 receptor 6PT0
TM5 223 V 5.49x49 CXCR2 6LFO CXCR2 6LFO
TM5 224 P 5.50x50 CXCR2 6LFO CXCR2 6LFO
TM5 225 F 5.51x51 CXCR2 6LFO AT1 receptor 6OS2
TM5 226 S 5.52x52 CXCR2 6LFO US28 5WB1
TM5 227 I 5.53x53 CXCR2 6LFO CXCR2 6LFO
TM5 228 I 5.54x54 CXCR2 6LFO AT1 receptor 6OS2
TM5 229 A 5.55x55 CXCR2 6LFO AT2 receptor 6JOD
TM5 230 V 5.56x56 CXCR2 6LFO κ receptor 6B73
TM5 231 F 5.57x57 CXCR2 6LFO GPR52 6LI3
TM5 232 Y 5.58x58 CXCR2 6LFO CXCR2 6LFO
TM5 233 F 5.59x59 CXCR2 6LFO AT2 receptor 6JOD
TM5 234 L 5.60x60 CXCR2 6LFO AT1 receptor 6OS2
TM5 235 L 5.61x61 CXCR2 6LFO Rhodopsin 4ZWJ
TM5 236 A 5.62x62 CXCR2 6LFO FPR2/ALX 6LW5
TM5 237 R 5.63x63 CXCR2 6LFO CXCR2 6LFO
TM5 238 A 5.64x64 CXCR2 6LFO AT1 receptor 6OS2
TM5 239 I 5.65x65 CXCR2 6LFO FPR2/ALX 6LW5
TM5 240 S 5.66x66 CXCR2 6LFO CXCR4 3OE0
TM5 241 A 5.67x67 CXCR2 6LFO BLT1 receptor 5X33
TM5 242 S 5.68x68 CXCR2 6LFO US28 5WB1
ICL3 243 S - - - -
ICL3 244 D - - - -
TM6 245 Q 6.28x28 CCR5 5UIW NTS1 receptor 6OSA
TM6 246 E 6.29x29 CXCR2 6LFO - -
TM6 247 K 6.30x30 CXCR2 6LFO CXCR2 6LFO
TM6 248 H 6.31x31 CXCR2 6LFO CXCR2 6LFO
TM6 249 S 6.32x32 CXCR2 6LFO PAR1 3VW7
TM6 250 S 6.33x33 CXCR2 6LFO MT2 receptor 6ME7
TM6 251 R 6.34x34 CXCR2 6LFO - -
TM6 252 K 6.35x35 CXCR2 6LFO AT1 receptor 6OS2
TM6 253 I 6.36x36 CXCR2 6LFO AT1 receptor 6OS2
TM6 254 I 6.37x37 CXCR2 6LFO CXCR2 6LFO
TM6 255 F 6.38x38 CXCR2 6LFO CXCR2 6LFO
TM6 256 S 6.39x39 CXCR2 6LFO Y1 receptor 5ZBH
TM6 257 Y 6.40x40 CXCR2 6LFO D2 receptor 6VMS
TM6 258 V 6.41x41 CXCR2 6LFO CXCR2 6LFO
TM6 259 V 6.42x42 CXCR2 6LFO δ receptor 6PT2
TM6 260 V 6.43x43 CXCR2 6LFO CCR6 6WWZ
TM6 261 F 6.44x44 CXCR2 6LFO CXCR2 6LFO
TM6 262 L 6.45x45 CXCR2 6LFO CXCR2 6LFO
TM6 263 V 6.46x46 CXCR2 6LFO κ receptor 6B73
TM6 264 C 6.47x47 CXCR2 6LFO CXCR2 6LFO
TM6 265 W 6.48x48 CXCR2 6LFO CXCR2 6LFO
TM6 266 L 6.49x49 CXCR2 6LFO CXCR2 6LFO
TM6 267 P 6.50x50 CXCR2 6LFO CXCR2 6LFO
TM6 268 Y 6.51x51 CXCR2 6LFO CXCR2 6LFO
TM6 269 H 6.52x52 CXCR2 6LFO US28 5WB1
TM6 270 V 6.53x53 CXCR2 6LFO AT2 receptor 6JOD
TM6 271 A 6.54x54 CXCR2 6LFO ETB receptor 5X93
TM6 272 V 6.55x55 CXCR2 6LFO μ receptor 5C1M
TM6 273 L 6.56x56 CXCR2 6LFO CXCR2 6LFO
TM6 274 L 6.57x57 CXCR2 6LFO AT1 receptor 6OS2
TM6 275 D 6.58x58 CXCR2 6LFO CXCR2 6LFO
TM6 276 I 6.59x59 CXCR2 6LFO D2 receptor 6VMS
TM6 277 F 6.60x60 CXCR2 6LFO M2 receptor 4MQT
TM6 278 S 6.61x61 CXCR2 6LFO ghrelin receptor 6KO5
TM6 279 I 6.62x62 CXCR2 6LFO PAR2 5NDD
TM6 280 L 6.63x63 AT1 receptor 4ZUD AT1 receptor 6OS2
TM6 281 H 6.64x64 AT1 receptor 4ZUD - -
ECL3 282 Y - - - -
ECL3 283 I CXCR4 3ODU CXCR4 3ODU
ECL3 284 P CXCR4 3ODU - -
ECL3 285 F - - - -
TM7 286 T 7.24x23 CXCR2 6LFO CXCR2 6LFO
TM7 287 C 7.25x24 CXCR2 6LFO CXCR2 6LFO
TM7 288 R 7.26x25 CXCR2 6LFO AT1 receptor 6DO1
TM7 289 L 7.27x26 CXCR2 6LFO NTS1 receptor 6OSA
TM7 290 E 7.28x27 CXCR2 6LFO CCR6 6WWZ
TM7 291 H 7.29x28 CXCR2 6LFO - -
TM7 292 A 7.30x29 CXCR2 6LFO κ receptor 6B73
TM7 293 L 7.31x30 CXCR2 6LFO US28 5WB1
TM7 294 F 7.32x31 CXCR2 6LFO P2Y12 receptor 4NTJ
TM7 295 T 7.33x32 CXCR2 6LFO AT1 receptor 6OS2
TM7 296 A 7.34x33 CXCR2 6LFO CXCR2 6LFO
TM7 297 L 7.35x34 CXCR2 6LFO CXCR2 6LFO
TM7 298 H 7.36x35 CXCR2 6LFO μ receptor 5C1M
TM7 299 V 7.37x36 CXCR2 6LFO CCR6 6WWZ
TM7 300 T 7.38x37 CXCR2 6LFO CXCR2 6LFO
TM7 301 Q 7.39x38 CXCR2 6LFO CCR9 5LWE
TM7 302 C 7.40x39 CXCR2 6LFO AT1 receptor 6OS2
TM7 303 L 7.41x40 CXCR2 6LFO CXCR2 6LFO
TM7 304 S 7.42x41 CXCR2 6LFO A2A receptor 4UHR
TM7 305 L 7.43x42 CXCR2 6LFO CB1 receptor 5XRA
TM7 306 V 7.44x43 CXCR2 6LFO NTS1 receptor 6OSA
TM7 307 H 7.45x45 CXCR2 6LFO CXCR2 6LFO
TM7 308 C 7.46x46 CXCR2 6LFO CCR6 6WWZ
TM7 309 C 7.47x47 CXCR2 6LFO CXCR2 6LFO
TM7 310 V 7.48x48 CXCR2 6LFO AT2 receptor 6JOD
TM7 311 N 7.49x49 CXCR2 6LFO CXCR2 6LFO
TM7 312 P 7.50x50 CXCR2 6LFO CXCR2 6LFO
TM7 313 V 7.51x51 CXCR2 6LFO CCR6 6WWZ
TM7 314 L 7.52x52 CXCR2 6LFO CCR6 6WWZ
TM7 315 Y 7.53x53 CXCR2 6LFO CXCR2 6LFO
TM7 316 S 7.54x54 CXCR2 6LFO GPR52 6LI3
TM7 317 F 7.55x55 CXCR2 6LFO CXCR2 6LFO
TM7 318 I 7.56x56 CXCR2 6LFO CXCR2 6LFO
H8 319 N 8.47x47 CXCR2 6LFO 5-HT2A receptor 6WHA
H8 320 R 8.48x48 CXCR2 6LFO A2A receptor 4UHR
H8 321 N 8.49x49 CXCR2 6LFO δ receptor 6PT2
H8 322 Y 8.50x50 CXCR2 6LFO 5-HT2A receptor 6WHA
H8 323 R 8.51x51 CXCR2 6LFO CXCR2 6LFO
H8 324 Y 8.52x52 CXCR2 6LFO - -
H8 325 E 8.53x53 CXCR2 6LFO US28 5WB1
H8 326 L 8.54x54 CXCR2 6LFO CXCR2 6LFO
H8 327 M 8.55x55 CXCR2 6LFO - -
H8 328 K 8.56x56 CXCR2 6LFO CXCR2 6LFO
H8 329 A 8.57x57 CXCR2 6LFO OX2 receptor 5WS3
H8 330 F 8.58x58 CXCR2 6LFO AT2 receptor 6JOD
H8 331 I 8.59x59 CXCR2 6LFO μ receptor 4DKL
H8 332 F 8.60x60 CXCR2 6LFO - -
H8 333 K 8.61x61 CXCR2 6LFO - -
C-term 334 Y - - - -
C-term 335 S - - - -
C-term 336 A - - - -
C-term 337 K - - - -
C-term 338 T - - - -