The RMSD values compare the latest model before a structure of the same receptor in the same state was published. Documentation
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ROOT-MEAN-SQUARE DEVIATION (Å)
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RECEPTOR
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EXPERIMENTAL STRUCTURE
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MODEL
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall all |
Overall backbone |
7TM all |
7TM backbone |
H8 | ICL1 | ECL1 | ICL2 | ECL2 | ECL3 |
UniProt
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IUPHAR | Receptor family | Cl. |
PDB
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State | Degree active (%) |
Version | Note | |
| 3.8 | 2.9 | 2.4 | 2.0 | 3.0 | 1.6 | 3.7 | 1.7 | 6.8 | 3.3 | 5HT4R | 5-HT4 | 5-Hydroxytryptamine | A (Rhodopsin) | 7XT8 | Active | 100 | 2022-08-16 | - | |
| 3.1 | 2.2 | 2.7 | 1.9 | - | - | 3.1 | 2.5 | 4.4 | 2.3 | 5HT5A | 5-HT5A | 5-Hydroxytryptamine | A (Rhodopsin) | 7UM4 | Inactive | 28 | 2022-08-16 | - | |
| 1.9 | 1.5 | 1.8 | 1.2 | 1.6 | 1.7 | 1.9 | 2.7 | 2.6 | 1.3 | 5HT5A | 5-HT5A | 5-Hydroxytryptamine | A (Rhodopsin) | 7UM5 | Active | 100 | 2022-08-16 | - | |
| 2.3 | 1.6 | 1.6 | 1.1 | 2.4 | 0.9 | 1.8 | 1.3 | 3.3 | 2.7 | 5HT6R | 5-HT6 | 5-Hydroxytryptamine | A (Rhodopsin) | 7XTB | Active | 100 | 2022-08-16 | - | |
| 2.8 | 2.1 | 2.3 | 1.7 | 4.2 | 1.2 | 0.9 | 0.8 | 4.4 | 2.1 | 5HT7R | 5-HT7 | 5-Hydroxytryptamine | A (Rhodopsin) | 7XTC | Active | 100 | 2022-08-16 | - | |