The RMSD values compare the latest model before a structure of the same receptor in the same state was published. Documentation


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ROOT-MEAN-SQUARE DEVIATION (Å)
RECEPTOR
EXPERIMENTAL STRUCTURE
MODEL
Overall
all
Overall
backbone
7TM
all
7TM
backbone
H8 ICL1 ECL1 ICL2 ECL2 ECL3
UniProt
IUPHAR Receptor family Cl.
PDB
State Degree
active (%)
Version Note
3.8 2.9 2.4 2.0 3.0 1.6 3.7 1.7 6.8 3.3 5HT4R 5-HT4 5-Hydroxytryptamine A (Rhodopsin) 7XT8 Active 100 2022-08-16 -
3.1 2.2 2.7 1.9 - - 3.1 2.5 4.4 2.3 5HT5A 5-HT5A 5-Hydroxytryptamine A (Rhodopsin) 7UM4 Inactive 28 2022-08-16 -
1.9 1.5 1.8 1.2 1.6 1.7 1.9 2.7 2.6 1.3 5HT5A 5-HT5A 5-Hydroxytryptamine A (Rhodopsin) 7UM5 Active 100 2022-08-16 -
2.3 1.6 1.6 1.1 2.4 0.9 1.8 1.3 3.3 2.7 5HT6R 5-HT6 5-Hydroxytryptamine A (Rhodopsin) 7XTB Active 100 2022-08-16 -
2.8 2.1 2.3 1.7 4.2 1.2 0.9 0.8 4.4 2.1 5HT7R 5-HT7 5-Hydroxytryptamine A (Rhodopsin) 7XTC Active 100 2022-08-16 -