Latest GPCRdb article
GPCRdb in 2023: State-specific structure models using AlphaFold2 and expansion of ligand resources.
Pándy-Szekeres, G., Caroli, J., Mamyrbekov, A., Kermani, A.A., Keserű, G.M., Kooistra, A.J. and Gloriam, D.E.
Nucleic Acids Research, 2023
Structure analysis platform
An online GPCR structure analysis platform.
Kooistra, A.J., Munk, C., Hauser, A.S. and Gloriam, D.E.
Nature Structural & Molecular Biology, 2021
Drug resource
Trends in GPCR drug discovery: new agents, targets and indications.
Hauser, A.S., Attwood, M.M., Rask-Andersen, M., Schioth, H.B. and Gloriam, D.E.
Nature Reviews Drug Discovery, 2017
Generic residue numbers
Generic GPCR residue numbers - aligning topology maps while minding the gaps.
Isberg, V., de Graaf, C., Bortolato, A., Cherezov, V., Katritch, V., Marshall, F.H., Mordalski, S., Pin, J.P., Stevens, R.C., Vriend, G. and Gloriam, D.E.
Trends in pharmacological sciences, 2015
Other publications
GPCRdb in 2021: integrating GPCR sequence, structure and function.
Kooistra, A.J., Mordalski, S., Pándy-Szekeres, G., Esguerra, M., Mamyrbekov, A., Munk, C., Keserű, G.M. and Gloriam, D.E.
Nucleic Acids Research, 2021
Combinatorial expression of GPCR isoforms affects signalling and drug responses.
Marti-Solano, M., Crilly, S.E., Malinverni, D., Munk, C., Harris, M., Pearce, A., Quon, T., Mackenzie, A.E., Wang, X., Peng, J. et al.
Nature, 2020
An online resource for GPCR structure determination and analysis.
Munk, C., Mutt, E., Isberg, V., Nikolajsen, L.F., Bibbe, J.M., Flock, T., Hanson, M.A., Stevens, R.C., Deupi, X. and Gloriam, D.E.
Nature Methods, 2019
GPCRdb in 2018: adding GPCR structure models and ligands.
Pándy-Szekeres, G., Munk, C., Tsonkov, T.M., Mordalski, S., Harpsoe, K., Hauser, A.S., Bojarski, A.J. and Gloriam, D.E.
Nucleic Acids Research, 2018
Pharmacogenomics of GPCR Drug Targets.
Hauser, A.S., Chavali, S., Masuho, I., Jahn, L.J., Martemyanov, K.A., Gloriam, D.E. and Babu, M.M.
Cell, 2018
GPCRdb: an information system for G protein-coupled receptors.
Isberg, V., Mordalski, S., Munk, C., Rataj, K., Harpsoe, K., Hauser, A.S., Vroling, B., Bojarski, A.J., Vriend, G. and Gloriam, D.E.
Nucleic Acids Research, 2016
GPCRdb: the G protein-coupled receptor database - an introduction.
Munk, C., Isberg, V., Mordalski, S., Harpsoe, K., Rataj, K., Hauser, A.S., Kolb, P., Bojarski, A.J., Vriend, G. and Gloriam, D.E.
British Journal of Pharmacololgy, 2016
Integrating structural and mutagenesis data to elucidate GPCR ligand binding.
Munk, C., Harpsoe, K., Hauser, A.S., Isberg, V. and Gloriam, D.E.
Current Opinion in Pharmacology, 2016
GPCRDB: an information system for G protein-coupled receptors.
Isberg, V., Vroling, B., van der Kant, R., Li, K., Vriend, G. and Gloriam, D.
Nucleic Acids Research, 2014