OR12D2 (o12d2_human)
FAMILY
Class O2 (tetrapod specific odorant) Odorant receptors Odorant family 12 OR12D2
GENE
OR12D2
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Olfactory receptor 12D2, Hs6M1-20, Olfactory receptor OR6-28
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
L
|
N
|
T
|
T
|
S
|
V
|
T
|
E
|
F
|
10 |
TM1 | |||||||||
L
|
L
|
L
|
G
|
V
|
T
|
D
|
I
|
Q
|
E
|
20 |
L
|
Q
|
P
|
F
|
L
|
F
|
V
|
V
|
F
|
L
|
30 |
T
|
I
|
Y
|
F
|
I
|
S
|
V
|
T
|
G
|
N
|
40 |
G
|
A
|
V
|
L
|
M
|
I
|
V
|
I
|
S
|
D
|
50 |
ICL1 | TM2 | ||||||||
P
|
R
|
L
|
H
|
S
|
L
|
M
|
Y
|
F
|
F
|
60 |
L
|
G
|
N
|
L
|
S
|
Y
|
L
|
D
|
I
|
C
|
70 |
Y
|
S
|
T
|
V
|
T
|
L
|
P
|
K
|
M
|
L
|
80 |
ECL1 | |||||||||
Q
|
N
|
F
|
L
|
S
|
T
|
H
|
K
|
A
|
I
|
90 |
TM3 | |||||||||
S
|
F
|
L
|
G
|
C
|
I
|
S
|
Q
|
L
|
H
|
100 |
F
|
F
|
H
|
S
|
L
|
G
|
S
|
T
|
E
|
S
|
110 |
M
|
L
|
F
|
A
|
V
|
M
|
A
|
F
|
D
|
L
|
120 |
ICL2 | |||||||||
S
|
V
|
A
|
I
|
C
|
K
|
P
|
L
|
R
|
Y
|
130 |
TM4 | |||||||||
T
|
V
|
I
|
M
|
N
|
P
|
Q
|
L
|
C
|
T
|
140 |
Q
|
M
|
A
|
I
|
T
|
I
|
W
|
V
|
I
|
G
|
150 |
F
|
F
|
H
|
A
|
L
|
L
|
H
|
S
|
V
|
M
|
160 |
ECL2 | |||||||||
T
|
S
|
R
|
L
|
N
|
F
|
C
|
G
|
S
|
N
|
170 |
R
|
I
|
H
|
H
|
F
|
L
|
C
|
D
|
I
|
K
|
180 |
P
|
L
|
L
|
K
|
L
|
A
|
C
|
G
|
N
|
T
|
190 |
TM5 | |||||||||
E
|
L
|
N
|
Q
|
W
|
L
|
L
|
S
|
T
|
V
|
200 |
T
|
G
|
T
|
I
|
A
|
M
|
G
|
P
|
F
|
F
|
210 |
L
|
T
|
L
|
L
|
S
|
Y
|
F
|
Y
|
I
|
I
|
220 |
T
|
Y
|
L
|
F
|
F
|
K
|
T
|
R
|
S
|
C
|
230 |
TM6 | |||||||||
S
|
M
|
L
|
C
|
K
|
A
|
L
|
S
|
T
|
C
|
240 |
A
|
S
|
H
|
F
|
M
|
V
|
V
|
I
|
L
|
F
|
250 |
Y
|
A
|
P
|
V
|
L
|
F
|
T
|
Y
|
I
|
H
|
260 |
ECL3 | TM7 | ||||||||
P
|
A
|
L
|
E
|
S
|
F
|
M
|
D
|
Q
|
D
|
270 |
R
|
I
|
V
|
A
|
I
|
M
|
Y
|
T
|
V
|
V
|
280 |
T
|
P
|
V
|
L
|
N
|
P
|
L
|
I
|
Y
|
T
|
290 |
H8 | |||||||||
L
|
R
|
N
|
K
|
E
|
V
|
K
|
G
|
A
|
L
|
300 |
G
|
R
|
V
|
I
|
R
|
R
|
L
|
LINKS
DIAGRAMS
7TM
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
No structures available