P2Y2 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive (Δ distance (Å): -1.43 docs)

VERSION

2020-07-30

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

μ receptor (sequence similarity: 43%) PDB: 4DKL

TEMPLATES

4DKL (μ receptor)
4XNW (P2Y1 receptor)
4NTJ (P2Y12 receptor)
4BUO (NTS1 receptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 81.1 10.9 7.9
Side-chains 23.2 57.3 19.5

Number of backbone templates: 4
Number of rotamer templates: 40

Segment Seq.num. GPCRdb# Backbone PDB Rotamer PDB
N-term 26 - - - -
N-term 27 - - - -
N-term 28 - - - -
N-term 29 - - - -
N-term 30 - - - -
TM1 31 1.30x30 μ receptor 4DKL CXCR4 3ODU
TM1 32 1.31x31 μ receptor 4DKL CCR7 6QZH
TM1 33 1.32x32 μ receptor 4DKL PAF receptor 5ZKQ
TM1 34 1.33x33 μ receptor 4DKL κ receptor 4DJH
TM1 35 1.34x34 μ receptor 4DKL CCR5 5UIW
TM1 36 1.35x35 μ receptor 4DKL CXCR4 3ODU
TM1 37 1.36x36 μ receptor 4DKL CXCR4 3ODU
TM1 38 1.37x37 μ receptor 4DKL C5a1 receptor 5O9H
TM1 39 1.38x38 μ receptor 4DKL D3 receptor 3PBL
TM1 40 1.39x39 μ receptor 4DKL μ receptor 4DKL
TM1 41 1.40x40 μ receptor 4DKL DP2 receptor 6D27
TM1 42 1.41x41 μ receptor 4DKL κ receptor 6VI4
TM1 43 1.42x42 μ receptor 4DKL μ receptor 4DKL
TM1 44 1.43x43 μ receptor 4DKL μ receptor 4DKL
TM1 45 1.44x44 μ receptor 4DKL μ receptor 4DKL
TM1 46 1.45x45 μ receptor 4DKL 5-HT2B receptor 4IB4
TM1 47 1.46x46 μ receptor 4DKL μ receptor 4DKL
TM1 48 1.47x47 μ receptor 4DKL μ receptor 4DKL
TM1 49 1.48x48 μ receptor 4DKL - -
TM1 50 1.49x49 μ receptor 4DKL H1 receptor 3RZE
TM1 51 1.50x50 μ receptor 4DKL μ receptor 4DKL
TM1 52 1.51x51 μ receptor 4DKL C5a1 receptor 5O9H
TM1 53 1.52x52 μ receptor 4DKL DP2 receptor 6D27
TM1 54 1.53x53 μ receptor 4DKL EP4 receptor 5YWY
TM1 55 1.54x54 μ receptor 4DKL DP2 receptor 6D27
TM1 56 1.55x55 μ receptor 4DKL μ receptor 4DKL
TM1 57 1.56x56 μ receptor 4DKL CCR5 5UIW
TM1 58 1.57x57 μ receptor 4DKL M1 receptor 5CXV
TM1 59 1.58x58 μ receptor 4DKL BLT1 receptor 5X33
TM1 60 1.59x59 μ receptor 4DKL DP2 receptor 6D27
TM1 61 1.60x60 μ receptor 4DKL - -
ICL1 62 μ receptor 4DKL - -
ICL1 63 μ receptor 4DKL μ receptor 4DKL
ICL1 64 μ receptor 4DKL - -
ICL1 65 μ receptor 4DKL - -
TM2 66 2.37x37 μ receptor 4DKL Y1 receptor 5ZBH
TM2 67 2.38x38 μ receptor 4DKL μ receptor 4DKL
TM2 68 2.39x39 μ receptor 4DKL CB1 receptor 5TGZ
TM2 69 2.40x40 μ receptor 4DKL DP2 receptor 6D27
TM2 70 2.41x41 μ receptor 4DKL CCR7 6QZH
TM2 71 2.42x42 μ receptor 4DKL μ receptor 4DKL
TM2 72 2.43x43 μ receptor 4DKL LPA1 receptor 4Z35
TM2 73 2.44x44 μ receptor 4DKL μ receptor 4DKL
TM2 74 2.45x45 μ receptor 4DKL CXCR4 3ODU
TM2 75 2.46x46 μ receptor 4DKL μ receptor 4DKL
TM2 76 2.47x47 μ receptor 4DKL μ receptor 4DKL
TM2 77 2.48x48 μ receptor 4DKL CXCR4 3ODU
TM2 78 2.49x49 μ receptor 4DKL DP2 receptor 6D27
TM2 79 2.50x50 μ receptor 4DKL μ receptor 4DKL
TM2 80 2.51x51 μ receptor 4DKL μ receptor 4DKL
TM2 81 2.52x52 μ receptor 4DKL μ receptor 4DKL
TM2 82 2.53x53 μ receptor 4DKL P2Y1 receptor 4XNW
TM2 83 2.54x54 μ receptor 4DKL Y1 receptor 5ZBH
TM2 84 2.55x55 μ receptor 4DKL DP2 receptor 6D27
TM2 85 2.56x56 μ receptor 4DKL DP2 receptor 6D27
TM2 86 2.57x57 μ receptor 4DKL μ receptor 4DKL
TM2 87 2.58x58 μ receptor 4DKL μ receptor 4DKL
TM2 88 2.59x59 μ receptor 4DKL apelin receptor 5VBL
TM2 89 2.60x60 μ receptor 4DKL C5a1 receptor 5O9H
TM2 90 2.61x61 μ receptor 4DKL ETB receptor 5X93
TM2 91 2.62x62 μ receptor 4DKL CCR7 6QZH
TM2 92 2.63x63 μ receptor 4DKL CCR5 5UIW
TM2 93 2.64x64 μ receptor 4DKL μ receptor 4DKL
TM2 94 2.65x65 μ receptor 4DKL CCR7 6QZH
TM2 95 2.66x66 μ receptor 4DKL apelin receptor 5VBL
ECL1 96 - - - -
ECL1 97 P2Y1 receptor 4XNW - -
ECL1 98 23.49x49 P2Y1 receptor 4XNW C5a1 receptor 5O9H
ECL1 99 23.50x50 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
ECL1 100 23.51x51 P2Y1 receptor 4XNW μ receptor 4DKL
ECL1 101 23.52x52 - - - -
TM3 102 3.21x21 μ receptor 4DKL D3 receptor 3PBL
TM3 103 3.22x22 μ receptor 4DKL DP2 receptor 6D27
TM3 104 3.23x23 μ receptor 4DKL κ receptor 6VI4
TM3 105 3.24x24 μ receptor 4DKL μ receptor 4DKL
TM3 106 3.25x25 μ receptor 4DKL μ receptor 4DKL
TM3 107 3.26x26 μ receptor 4DKL μ receptor 4DKL
TM3 108 3.27x27 μ receptor 4DKL CCR7 6QZH
TM3 109 3.28x28 μ receptor 4DKL μ receptor 4DKL
TM3 110 3.29x29 μ receptor 4DKL P2Y1 receptor 4XNW
TM3 111 3.30x30 μ receptor 4DKL Y1 receptor 5ZBH
TM3 112 3.31x31 μ receptor 4DKL CCR5 5UIW
TM3 113 3.32x32 μ receptor 4DKL DP2 receptor 6D27
TM3 114 3.33x33 μ receptor 4DKL μ receptor 4DKL
TM3 115 3.34x34 μ receptor 4DKL 5-HT1B receptor 4IAQ
TM3 116 3.35x35 μ receptor 4DKL μ receptor 4DKL
TM3 117 3.36x36 μ receptor 4DKL CXCR4 3ODU
TM3 118 3.37x37 μ receptor 4DKL CXCR4 3ODU
TM3 119 3.38x38 μ receptor 4DKL PAR2 5NDD
TM3 120 3.39x39 μ receptor 4DKL μ receptor 4DKL
TM3 121 3.40x40 μ receptor 4DKL μ receptor 4DKL
TM3 122 3.41x41 μ receptor 4DKL CCR9 5LWE
TM3 123 3.42x42 μ receptor 4DKL CCR5 5UIW
TM3 124 3.43x43 μ receptor 4DKL μ receptor 4DKL
TM3 125 3.44x44 μ receptor 4DKL κ receptor 6VI4
TM3 126 3.45x45 μ receptor 4DKL CCR7 6QZH
TM3 127 3.46x46 μ receptor 4DKL CXCR4 3ODU
TM3 128 3.47x47 μ receptor 4DKL μ receptor 4DKL
TM3 129 3.48x48 μ receptor 4DKL μ receptor 4DKL
TM3 130 3.49x49 μ receptor 4DKL P2Y1 receptor 4XNW
TM3 131 3.50x50 μ receptor 4DKL μ receptor 4DKL
TM3 132 3.51x51 μ receptor 4DKL DP2 receptor 6D27
TM3 133 3.52x52 μ receptor 4DKL CXCR4 3ODU
TM3 134 3.53x53 μ receptor 4DKL P2Y1 receptor 4XNW
TM3 135 3.54x54 μ receptor 4DKL μ receptor 4DKL
TM3 136 3.55x55 μ receptor 4DKL FPR2/ALX 6LW5
TM3 137 3.56x56 μ receptor 4DKL DP2 receptor 6D27
ICL2 138 34.50x50 - - - -
ICL2 139 34.51x51 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
ICL2 140 34.52x52 P2Y1 receptor 4XNW CCR9 5LWE
ICL2 141 34.53x53 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
ICL2 142 34.54x54 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
ICL2 143 34.55x55 P2Y1 receptor 4XNW C5a1 receptor 5O9H
ICL2 144 34.56x56 P2Y1 receptor 4XNW CCR9 5LWE
ICL2 145 34.57x57 - - - -
TM4 146 4.38x38 μ receptor 4DKL FFA1 receptor 5TZY
TM4 147 4.39x39 μ receptor 4DKL C5a1 receptor 5O9H
TM4 148 4.40x40 μ receptor 4DKL μ receptor 4DKL
TM4 149 4.41x41 μ receptor 4DKL CCR9 5LWE
TM4 150 4.42x42 μ receptor 4DKL μ receptor 4DKL
TM4 151 4.43x43 μ receptor 4DKL BLT1 receptor 5X33
TM4 152 4.44x44 μ receptor 4DKL - -
TM4 153 4.45x45 μ receptor 4DKL μ receptor 4DKL
TM4 154 4.46x46 μ receptor 4DKL - -
TM4 155 4.47x47 μ receptor 4DKL M1 receptor 5CXV
TM4 156 4.48x48 μ receptor 4DKL NOP receptor 5DHG
TM4 157 4.49x49 μ receptor 4DKL CXCR4 3ODU
TM4 158 4.50x50 μ receptor 4DKL μ receptor 4DKL
TM4 159 4.51x51 μ receptor 4DKL CCR9 5LWE
TM4 160 4.52x52 μ receptor 4DKL μ receptor 4DKL
TM4 161 4.53x53 μ receptor 4DKL P2Y1 receptor 4XNW
TM4 162 4.54x54 μ receptor 4DKL CXCR4 3ODU
TM4 163 4.55x55 μ receptor 4DKL μ receptor 4DKL
TM4 164 4.56x56 μ receptor 4DKL Rhodopsin 1GZM
TM4 165 4.57x57 μ receptor 4DKL - -
TM4 166 4.58x58 μ receptor 4DKL Rhodopsin 1GZM
TM4 167 4.59x59 μ receptor 4DKL μ receptor 4DKL
TM4 168 4.60x60 μ receptor 4DKL μ receptor 4DKL
TM4 169 4.61x61 μ receptor 4DKL Rhodopsin 1GZM
TM4 170 4.62x62 μ receptor 4DKL PAR2 5NDD
TM4 171 4.63x63 μ receptor 4DKL NTS1 receptor 4BUO
TM4 172 4.64x64 μ receptor 4DKL - -
ECL2 173 μ receptor 4DKL μ receptor 4DKL
ECL2 174 μ receptor 4DKL μ receptor 4DKL
ECL2 175 μ receptor 4DKL - -
ECL2 176 μ receptor 4DKL - -
ECL2 177 μ receptor 4DKL μ receptor 4DKL
ECL2 178 μ receptor 4DKL - -
ECL2 179 μ receptor 4DKL μ receptor 4DKL
ECL2 180 μ receptor 4DKL - -
ECL2 181 μ receptor 4DKL - -
ECL2 182 μ receptor 4DKL - -
ECL2 183 45.50x50 μ receptor 4DKL μ receptor 4DKL
ECL2 184 45.51x51 μ receptor 4DKL - -
ECL2 185 45.52x52 μ receptor 4DKL Y1 receptor 5ZBH
ECL2 186 - - - -
ECL2 187 P2Y1 receptor 4XNW - -
ECL2 188 P2Y1 receptor 4XNW - -
ECL2 189 P2Y1 receptor 4XNW - -
ECL2 190 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
ECL2 191 - - - -
TM5 192 5.32x33 μ receptor 4DKL - -
TM5 193 5.33x34 μ receptor 4DKL DP2 receptor 6D27
TM5 194 5.34x35 μ receptor 4DKL DP2 receptor 6D27
TM5 195 5.35x36 μ receptor 4DKL CCR7 6QZH
TM5 196 5.36x37 μ receptor 4DKL CXCR4 3ODU
TM5 197 5.37x38 μ receptor 4DKL DP2 receptor 6D27
TM5 198 5.38x39 μ receptor 4DKL Y1 receptor 5ZBH
TM5 199 5.39x40 μ receptor 4DKL EP4 receptor 5YWY
TM5 200 5.40x41 μ receptor 4DKL OX1 receptor 6TO7
TM5 201 5.41x42 μ receptor 4DKL C5a1 receptor 5O9H
TM5 202 5.42x43 μ receptor 4DKL Rhodopsin 1GZM
TM5 203 5.43x44 μ receptor 4DKL C5a1 receptor 5O9H
TM5 204 5.44x45 μ receptor 4DKL EP4 receptor 5YWY
TM5 205 5.45x46 μ receptor 4DKL DP2 receptor 6D27
TM5 206 5.46x461 μ receptor 4DKL FFA1 receptor 5TZY
TM5 207 5.47x47 μ receptor 4DKL μ receptor 4DKL
TM5 208 5.48x48 μ receptor 4DKL OX2 receptor 6TPN
TM5 209 5.49x49 μ receptor 4DKL CCR7 6QZH
TM5 210 5.50x50 μ receptor 4DKL μ receptor 4DKL
TM5 211 5.51x51 μ receptor 4DKL apelin receptor 5VBL
TM5 212 5.52x52 μ receptor 4DKL DP2 receptor 6D27
TM5 213 5.53x53 μ receptor 4DKL CXCR4 3ODU
TM5 214 5.54x54 μ receptor 4DKL μ receptor 4DKL
TM5 215 5.55x55 μ receptor 4DKL CXCR4 3ODU
TM5 216 5.56x56 μ receptor 4DKL μ receptor 4DKL
TM5 217 5.57x57 μ receptor 4DKL μ receptor 4DKL
TM5 218 5.58x58 μ receptor 4DKL μ receptor 4DKL
TM5 219 5.59x59 μ receptor 4DKL EP4 receptor 5YWY
TM5 220 5.60x60 μ receptor 4DKL μ receptor 4DKL
TM5 221 5.61x61 μ receptor 4DKL μ receptor 4DKL
TM5 222 5.62x62 μ receptor 4DKL apelin receptor 5VBL
TM5 223 5.63x63 μ receptor 4DKL BLT1 receptor 5X33
TM5 224 5.64x64 P2Y12 receptor 4NTJ κ receptor 6VI4
TM5 225 5.65x65 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
TM5 226 5.66x66 P2Y12 receptor 4NTJ CCR5 5UIW
TM5 227 5.67x67 P2Y12 receptor 4NTJ 5-HT2A receptor 6A94
TM5 228 5.68x68 P2Y12 receptor 4NTJ - -
TM5 229 5.69x69 P2Y12 receptor 4NTJ 5-HT2C receptor 6BQH
TM5 230 5.70x70 P2Y12 receptor 4NTJ - -
TM5 231 5.71x71 P2Y12 receptor 4NTJ - -
TM5 232 5.72x72 P2Y12 receptor 4NTJ P2Y12 receptor 4NTJ
ICL3 233 - - - -
ICL3 234 - - - -
ICL3 235 - - - -
ICL3 236 - - - -
ICL3 237 - - - -
ICL3 238 - - - -
TM6 239 6.29x30 μ receptor 4DKL NK1 receptor 6HLP
TM6 240 6.30x31 μ receptor 4DKL Y1 receptor 5ZBH
TM6 241 6.31x32 μ receptor 4DKL μ receptor 4DKL
TM6 242 6.32x33 μ receptor 4DKL P2Y1 receptor 4XNW
TM6 243 6.33x34 μ receptor 4DKL 5-HT2C receptor 6BQH
TM6 244 6.34x35 μ receptor 4DKL MT1 receptor 6ME2
TM6 245 6.35x36 μ receptor 4DKL - -
TM6 246 6.36x37 μ receptor 4DKL CXCR4 3ODU
TM6 247 6.37x38 μ receptor 4DKL CCR7 6QZH
TM6 248 6.38x39 μ receptor 4DKL CCR7 6QZH
TM6 249 6.39x40 μ receptor 4DKL μ receptor 4DKL
TM6 250 6.40x41 μ receptor 4DKL μ receptor 4DKL
TM6 251 6.41x42 μ receptor 4DKL CXCR4 3ODU
TM6 252 6.42x43 μ receptor 4DKL CXCR4 3ODU
TM6 253 6.43x44 μ receptor 4DKL EP4 receptor 5YWY
TM6 254 6.44x45 μ receptor 4DKL CXCR4 3ODU
TM6 255 6.45x46 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
TM6 256 6.46x461 P2Y1 receptor 4XNW CysLT2 receptor 6RZ6
TM6 257 6.47x47 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
TM6 258 6.48x48 μ receptor 4DKL MT1 receptor 6ME2
TM6 259 6.49x49 μ receptor 4DKL CXCR4 3ODU
TM6 260 6.50x50 μ receptor 4DKL μ receptor 4DKL
TM6 261 6.51x51 μ receptor 4DKL NK1 receptor 6HLP
TM6 262 6.52x52 μ receptor 4DKL μ receptor 4DKL
TM6 263 6.53x53 μ receptor 4DKL DP2 receptor 6D27
TM6 264 6.54x54 μ receptor 4DKL C5a1 receptor 5O9H
TM6 265 6.55x55 μ receptor 4DKL NTS1 receptor 4BUO
TM6 266 6.56x56 μ receptor 4DKL apelin receptor 5VBL
TM6 267 6.57x57 μ receptor 4DKL DP2 receptor 6D27
TM6 268 6.58x58 μ receptor 4DKL apelin receptor 5VBL
TM6 269 6.59x59 μ receptor 4DKL NK1 receptor 6HLP
TM6 270 6.60x60 μ receptor 4DKL BLT1 receptor 5X33
TM6 271 6.61x61 μ receptor 4DKL OX1 receptor 4ZJ8
ECL3 272 - - - -
ECL3 273 NTS1 receptor 4BUO - -
ECL3 274 NTS1 receptor 4BUO - -
ECL3 275 NTS1 receptor 4BUO - -
ECL3 276 - - - -
TM7 277 7.24x23 P2Y1 receptor 4XNW - -
TM7 278 7.25x24 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
TM7 279 7.26x25 P2Y1 receptor 4XNW - -
TM7 280 7.27x26 P2Y1 receptor 4XNW C5a1 receptor 5O9H
TM7 281 7.28x27 μ receptor 4DKL - -
TM7 282 7.29x28 μ receptor 4DKL CXCR4 3ODU
TM7 283 7.30x29 μ receptor 4DKL CCR9 5LWE
TM7 284 7.31x30 μ receptor 4DKL CCR9 5LWE
TM7 285 7.32x31 μ receptor 4DKL CCR7 6QZH
TM7 286 7.33x32 μ receptor 4DKL 5-HT2B receptor 4IB4
TM7 287 7.34x33 μ receptor 4DKL CCR7 6QZH
TM7 288 7.35x34 μ receptor 4DKL κ receptor 6VI4
TM7 289 7.36x35 μ receptor 4DKL BLT1 receptor 5X33
TM7 290 7.37x36 μ receptor 4DKL CCR7 6QZH
TM7 291 7.38x37 μ receptor 4DKL CXCR4 3ODU
TM7 292 7.39x38 μ receptor 4DKL P2Y1 receptor 4XNW
TM7 293 7.40x39 μ receptor 4DKL succinate receptor 6RNK
TM7 294 7.41x40 μ receptor 4DKL μ receptor 4DKL
TM7 295 7.42x41 μ receptor 4DKL CXCR4 3ODU
TM7 296 7.43x42 μ receptor 4DKL ETB receptor 5X93
TM7 297 7.44x43 μ receptor 4DKL δ receptor 4N6H
TM7 298 7.45x45 μ receptor 4DKL μ receptor 4DKL
TM7 299 7.46x46 μ receptor 4DKL μ receptor 4DKL
TM7 300 7.47x47 μ receptor 4DKL μ receptor 4DKL
TM7 301 7.48x48 μ receptor 4DKL μ receptor 4DKL
TM7 302 7.49x49 μ receptor 4DKL EP4 receptor 5YWY
TM7 303 7.50x50 μ receptor 4DKL μ receptor 4DKL
TM7 304 7.51x51 μ receptor 4DKL μ receptor 4DKL
TM7 305 7.52x52 μ receptor 4DKL μ receptor 4DKL
TM7 306 7.53x53 μ receptor 4DKL μ receptor 4DKL
TM7 307 7.54x54 μ receptor 4DKL P2Y1 receptor 4XNW
TM7 308 7.55x55 μ receptor 4DKL DP2 receptor 6D27
TM7 309 7.56x56 μ receptor 4DKL C5a1 receptor 5O9H
H8 310 8.47x47 μ receptor 4DKL CCR9 5LWE
H8 311 8.48x48 μ receptor 4DKL MT1 receptor 6ME2
H8 312 8.49x49 μ receptor 4DKL CCR9 5LWE
H8 313 8.50x50 μ receptor 4DKL CB1 receptor 5TGZ
H8 314 8.51x51 μ receptor 4DKL - -
H8 315 8.52x52 μ receptor 4DKL μ receptor 4DKL
H8 316 8.53x53 μ receptor 4DKL - -
H8 317 8.54x54 μ receptor 4DKL EP4 receptor 5YWY
H8 318 8.55x55 μ receptor 4DKL κ receptor 6VI4
H8 319 8.56x56 μ receptor 4DKL κ receptor 6VI4
H8 320 8.57x57 μ receptor 4DKL ETB receptor 5X93
H8 321 8.58x58 μ receptor 4DKL - -
H8 322 8.59x59 μ receptor 4DKL - -
C-term 323 - - - -
C-term 324 - - - -
C-term 325 - - - -
C-term 326 - - - -
C-term 327 - - - -