oxoglutarate receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

oxoglutarate receptor

SPECIES

Homo sapiens

STATE

Inactive

VERSION

2021-01-08

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

CCR7 (sequence similarity: 47%) PDB: 6QZH
Align

TEMPLATES

6QZH (CCR7)
4XNW (P2Y1 receptor)
6RNK (succinate receptor)
5UIW (CCR5)
5UNF (AT2 receptor)
6JOD (AT2 receptor)
4BUO (NTS1 receptor)
6RZ6 (CysLT2 receptor)
5NDD (PAR2)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 74.2 18.5 7.4
Side-chains 23.8 57.7 18.5

Number of backbone templates: 9
Number of rotamer templates: 49

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 26 D - - - -
N-term 27 E CCR7 6QZH CCR7 6QZH
N-term 28 N CCR7 6QZH CCR7 6QZH
N-term 29 I CCR7 6QZH CCR7 6QZH
N-term 30 P CCR7 6QZH CCR7 6QZH
TM1 31 L 1.30x30 CCR7 6QZH GnRH1 receptor 7BR3
TM1 32 K 1.31x31 CCR7 6QZH CCR7 6QZH
TM1 33 M 1.32x32 CCR7 6QZH M4 receptor 6KP6
TM1 34 H 1.33x33 CCR7 6QZH CCR9 5LWE
TM1 35 Y 1.34x34 CCR7 6QZH P2Y1 receptor 4XNW
TM1 36 L 1.35x35 CCR7 6QZH CCR7 6QZH
TM1 37 P 1.36x36 CCR7 6QZH CCR7 6QZH
TM1 38 V 1.37x37 CCR7 6QZH C5a1 receptor 5O9H
TM1 39 I 1.38x38 CCR7 6QZH CXCR4 3ODU
TM1 40 Y 1.39x39 CCR7 6QZH CCR7 6QZH
TM1 41 G 1.40x40 CCR7 6QZH Y1 receptor 5ZBH
TM1 42 I 1.41x41 CCR7 6QZH CCR7 6QZH
TM1 43 I 1.42x42 CCR7 6QZH CCR7 6QZH
TM1 44 F 1.43x43 CCR7 6QZH CCR5 5UIW
TM1 45 L 1.44x44 CCR7 6QZH CXCR4 3ODU
TM1 46 V 1.45x45 CCR7 6QZH CCR7 6QZH
TM1 47 G 1.46x46 CCR7 6QZH CCR7 6QZH
TM1 48 F 1.47x47 CCR7 6QZH CCR5 5UIW
TM1 49 P 1.48x48 CCR7 6QZH BLT1 receptor 5X33
TM1 50 G 1.49x49 CCR7 6QZH CCR7 6QZH
TM1 51 N 1.50x50 CCR7 6QZH CCR7 6QZH
TM1 52 A 1.51x51 CCR7 6QZH C5a1 receptor 5O9H
TM1 53 V 1.52x52 CCR7 6QZH NTS1 receptor 4BUO
TM1 54 V 1.53x53 CCR7 6QZH CCR7 6QZH
TM1 55 I 1.54x54 CCR7 6QZH CCR5 5UIW
TM1 56 S 1.55x55 CCR7 6QZH TP receptor 6IIV
TM1 57 T 1.56x56 CCR7 6QZH CCR7 6QZH
TM1 58 Y 1.57x57 CCR7 6QZH CCR7 6QZH
TM1 59 I 1.58x58 CCR7 6QZH CCR7 6QZH
TM1 60 F 1.59x59 CCR7 6QZH P2Y1 receptor 4XNW
TM1 61 K 1.60x60 P2Y1 receptor 4XNW PAR1 3VW7
ICL1 62 M - - - -
ICL1 63 R P2Y1 receptor 4XNW - -
ICL1 64 P P2Y1 receptor 4XNW P2Y1 receptor 4XNW
ICL1 65 W - - - -
TM2 66 K 2.37x37 CCR7 6QZH CB2 receptor 5ZTY
TM2 67 S 2.38x38 CCR7 6QZH apelin receptor 5VBL
TM2 68 S 2.39x39 CCR7 6QZH CB1 receptor 5TGZ
TM2 69 T 2.40x40 CCR7 6QZH DP2 receptor 6D27
TM2 70 I 2.41x41 CCR7 6QZH CCR5 5UIW
TM2 71 I 2.42x42 CCR7 6QZH Rhodopsin 1GZM
TM2 72 M 2.43x43 CCR7 6QZH OT receptor 6TPK
TM2 73 L 2.44x44 CCR7 6QZH CCR7 6QZH
TM2 74 N 2.45x45 CCR7 6QZH CCR7 6QZH
TM2 75 L 2.46x46 CCR7 6QZH CCR7 6QZH
TM2 76 A 2.47x47 CCR7 6QZH CCR7 6QZH
TM2 77 C 2.48x48 CCR7 6QZH β2-adrenoceptor 5JQH
TM2 78 T 2.49x49 CCR7 6QZH 5-HT1B receptor 4IAQ
TM2 79 D 2.50x50 CCR7 6QZH CCR7 6QZH
TM2 80 L 2.51x51 CCR7 6QZH CCR5 5UIW
TM2 81 L 2.52x52 CCR7 6QZH CCR7 6QZH
TM2 82 Y 2.53x53 CCR7 6QZH P2Y1 receptor 4XNW
TM2 83 L 2.54x54 CCR7 6QZH CCR7 6QZH
TM2 84 T 2.55x55 CCR7 6QZH κ receptor 6VI4
TM2 85 S 2.56x56 CCR7 6QZH DP2 receptor 6D27
TM2 86 L 2.57x57 CCR7 6QZH CCR7 6QZH
TM2 87 P 2.58x58 CCR7 6QZH CCR7 6QZH
TM2 88 F 2.59x59 CCR7 6QZH CCR7 6QZH
TM2 89 L 2.60x60 CCR7 6QZH C5a1 receptor 5O9H
TM2 90 I 2.61x61 CCR7 6QZH H1 receptor 3RZE
TM2 91 H 2.62x62 CCR7 6QZH CCR5 5UIW
TM2 92 Y 2.63x63 CCR7 6QZH CCR5 5UIW
TM2 93 Y 2.64x64 CCR7 6QZH κ receptor 6VI4
TM2 94 A 2.65x65 CCR7 6QZH CCR7 6QZH
TM2 95 S 2.66x66 CCR7 6QZH EP3 receptor 6AK3
ECL1 96 G - - - -
ECL1 97 E P2Y1 receptor 4XNW - -
ECL1 98 N 23.49x49 P2Y1 receptor 4XNW CXCR4 3ODU
ECL1 99 W 23.50x50 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
ECL1 100 I 23.51x51 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
ECL1 101 F 23.52x52 - - - -
TM3 102 G 3.21x21 CCR7 6QZH CCR7 6QZH
TM3 103 D 3.22x22 CCR7 6QZH NTS1 receptor 4BUO
TM3 104 F 3.23x23 CCR7 6QZH CXCR4 3ODU
TM3 105 M 3.24x24 CCR7 6QZH CCR5 5UIW
TM3 106 C 3.25x25 CCR7 6QZH CCR7 6QZH
TM3 107 K 3.26x26 CCR7 6QZH CCR7 6QZH
TM3 108 F 3.27x27 CCR7 6QZH β2-adrenoceptor 5JQH
TM3 109 I 3.28x28 CCR7 6QZH CCR7 6QZH
TM3 110 R 3.29x29 CCR7 6QZH P2Y1 receptor 4XNW
TM3 111 F 3.30x30 CCR7 6QZH NTS1 receptor 4BUO
TM3 112 S 3.31x31 CCR7 6QZH AT1 receptor 4ZUD
TM3 113 F 3.32x32 CCR7 6QZH DP2 receptor 6D27
TM3 114 H 3.33x33 CCR7 6QZH CCR2 5T1A
TM3 115 F 3.34x34 CCR7 6QZH AT1 receptor 4ZUD
TM3 116 N 3.35x35 CCR7 6QZH CXCR4 3ODU
TM3 117 L 3.36x36 CCR7 6QZH CXCR4 3ODU
TM3 118 Y 3.37x37 CCR7 6QZH CXCR4 3ODU
TM3 119 S 3.38x38 CCR7 6QZH CCR7 6QZH
TM3 120 S 3.39x39 CCR7 6QZH CXCR4 3ODU
TM3 121 I 3.40x40 CCR7 6QZH CCR5 5UIW
TM3 122 L 3.41x41 CCR7 6QZH CCR9 5LWE
TM3 123 F 3.42x42 CCR7 6QZH CCR5 5UIW
TM3 124 L 3.43x43 CCR7 6QZH CCR7 6QZH
TM3 125 T 3.44x44 CCR7 6QZH apelin receptor 5VBL
TM3 126 C 3.45x45 CCR7 6QZH CCR7 6QZH
TM3 127 F 3.46x46 CCR7 6QZH - -
TM3 128 S 3.47x47 CCR7 6QZH CCR7 6QZH
TM3 129 I 3.48x48 CCR7 6QZH CCR7 6QZH
TM3 130 F 3.49x49 CCR7 6QZH CysLT1 receptor 6RZ4
TM3 131 R 3.50x50 CCR7 6QZH CCR7 6QZH
TM3 132 Y 3.51x51 CCR7 6QZH CCR7 6QZH
TM3 133 C 3.52x52 CCR7 6QZH - -
TM3 134 V 3.53x53 CCR7 6QZH Rhodopsin 1GZM
TM3 135 I 3.54x54 CCR7 6QZH CCR7 6QZH
TM3 136 I 3.55x55 CCR7 6QZH - -
TM3 137 H 3.56x56 P2Y1 receptor 4XNW CCR5 5UIW
ICL2 138 P 34.50x50 - - - -
ICL2 139 M 34.51x51 P2Y1 receptor 4XNW CCR9 5LWE
ICL2 140 S 34.52x52 P2Y1 receptor 4XNW M1 receptor 6WJC
ICL2 141 C 34.53x53 P2Y1 receptor 4XNW C5a1 receptor 5O9H
ICL2 142 F 34.54x54 P2Y1 receptor 4XNW CCR6 6WWZ
ICL2 143 S 34.55x55 P2Y1 receptor 4XNW β2-adrenoceptor 3SN6
ICL2 144 I 34.56x56 P2Y1 receptor 4XNW CB1 receptor 5TGZ
ICL2 145 H 34.57x57 - - - -
TM4 146 K 4.38x38 CCR7 6QZH CXCR4 3ODU
TM4 147 T 4.39x39 CCR7 6QZH M2 receptor 5ZKC
TM4 148 R 4.40x40 CCR7 6QZH μ receptor 4DKL
TM4 149 C 4.41x41 CCR7 6QZH - -
TM4 150 A 4.42x42 CCR7 6QZH C5a1 receptor 5O9H
TM4 151 V 4.43x43 CCR7 6QZH CCR5 5UIW
TM4 152 V 4.44x44 CCR7 6QZH CCR5 5UIW
TM4 153 A 4.45x45 CCR7 6QZH apelin receptor 5VBL
TM4 154 C 4.46x46 CCR7 6QZH CCR7 6QZH
TM4 155 A 4.47x47 CCR7 6QZH apelin receptor 5VBL
TM4 156 V 4.48x48 CCR7 6QZH apelin receptor 5VBL
TM4 157 V 4.49x49 CCR7 6QZH CXCR4 3ODU
TM4 158 W 4.50x50 CCR7 6QZH CCR7 6QZH
TM4 159 I 4.51x51 CCR7 6QZH CCR7 6QZH
TM4 160 I 4.52x52 CCR7 6QZH 5-HT2C receptor 6BQH
TM4 161 S 4.53x53 CCR7 6QZH NTS1 receptor 4BUO
TM4 162 L 4.54x54 CCR7 6QZH CXCR4 3ODU
TM4 163 V 4.55x55 CCR7 6QZH CCR7 6QZH
TM4 164 A 4.56x56 CCR7 6QZH CCR5 5UIW
TM4 165 V 4.57x57 CCR7 6QZH MT1 receptor 6ME2
TM4 166 I 4.58x59 CCR7 6QZH CCR7 6QZH
TM4 167 P 4.59x60 CCR7 6QZH CCR7 6QZH
TM4 168 M 4.60x61 CCR7 6QZH NTS1 receptor 4BUO
TM4 169 T 4.61x62 CCR7 6QZH - -
TM4 170 F 4.62x63 CCR7 6QZH NTS1 receptor 4BUO
TM4 171 L 4.63x64 CCR7 6QZH apelin receptor 5VBL
TM4 172 I 4.64x65 succinate receptor 6RNK succinate receptor 6RNK
ECL2 173 T - - - -
ECL2 174 S CCR5 5UIW CCR5 5UIW
ECL2 175 T CCR5 5UIW - -
ECL2 176 N CCR5 5UIW - -
ECL2 177 R CCR5 5UIW - -
ECL2 178 T CCR5 5UIW - -
ECL2 179 N CCR5 5UIW - -
ECL2 180 R CCR5 5UIW - -
ECL2 181 S CCR5 5UIW - -
ECL2 182 A - - - -
ECL2 183 C 45.50x50 CCR7 6QZH CCR7 6QZH
ECL2 184 L 45.51x51 CCR7 6QZH ETB receptor 5X93
ECL2 185 D 45.52x52 CCR7 6QZH Y1 receptor 5ZBH
ECL2 186 L - - - -
ECL2 187 T AT2 receptor 5UNF - -
ECL2 188 S AT2 receptor 5UNF - -
ECL2 189 S AT2 receptor 5UNF - -
ECL2 190 D AT2 receptor 5UNF - -
ECL2 191 E - - - -
TM5 192 L 5.32x33 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
TM5 193 N 5.33x34 P2Y1 receptor 4XNW CXCR2 6LFL
TM5 194 T 5.34x35 P2Y1 receptor 4XNW NTS1 receptor 4BUO
TM5 195 I 5.35x36 CCR7 6QZH - -
TM5 196 K 5.36x37 CCR7 6QZH NTS1 receptor 4BUO
TM5 197 W 5.37x38 CCR7 6QZH H1 receptor 3RZE
TM5 198 Y 5.38x39 CCR7 6QZH OX2 receptor 5WS3
TM5 199 N 5.39x40 CCR7 6QZH GnRH1 receptor 7BR3
TM5 200 L 5.40x41 CCR7 6QZH CCR5 5UIW
TM5 201 I 5.41x42 CCR7 6QZH 5-HT2C receptor 6BQH
TM5 202 L 5.42x43 CCR7 6QZH Y1 receptor 5ZBH
TM5 203 T 5.43x44 CCR7 6QZH NTS1 receptor 4BUO
TM5 204 A 5.44x45 CCR7 6QZH - -
TM5 205 T 5.45x46 CCR7 6QZH BLT1 receptor 5X33
TM5 206 T 5.46x461 CCR7 6QZH OX2 receptor 5WS3
TM5 207 F 5.47x47 CCR7 6QZH CCR7 6QZH
TM5 208 C 5.48x48 CCR7 6QZH ETB receptor 5X93
TM5 209 L 5.49x49 CCR7 6QZH CCR5 5UIW
TM5 210 P 5.50x50 CCR7 6QZH CCR7 6QZH
TM5 211 L 5.51x51 CCR7 6QZH CCR7 6QZH
TM5 212 V 5.52x52 CCR7 6QZH β2-adrenoceptor 5JQH
TM5 213 I 5.53x53 CCR7 6QZH CCR2 5T1A
TM5 214 V 5.54x54 CCR7 6QZH BLT1 receptor 5X33
TM5 215 T 5.55x55 CCR7 6QZH C5a1 receptor 5O9H
TM5 216 L 5.56x56 CCR7 6QZH OX2 receptor 5WS3
TM5 217 C 5.57x57 CCR7 6QZH CCR7 6QZH
TM5 218 Y 5.58x58 CCR7 6QZH CCR7 6QZH
TM5 219 T 5.59x59 CCR7 6QZH NTS1 receptor 4BUO
TM5 220 T 5.60x60 CCR7 6QZH - -
TM5 221 I 5.61x61 CCR7 6QZH CCR7 6QZH
TM5 222 I 5.62x62 CCR7 6QZH CCR7 6QZH
TM5 223 H 5.63x63 P2Y1 receptor 4XNW 5-HT2B receptor 4IB4
TM5 224 T 5.64x64 P2Y1 receptor 4XNW CCR5 5UIW
TM5 225 L 5.65x65 P2Y1 receptor 4XNW P2Y1 receptor 4XNW
TM5 226 T 5.66x66 P2Y1 receptor 4XNW NTS1 receptor 4BUO
TM5 227 H 5.67x67 P2Y1 receptor 4XNW CXCR4 3OE0
ICL3 228 G - - - -
ICL3 229 L - - - -
ICL3 230 Q - - - -
ICL3 231 T - - - -
TM6 232 D 6.26x26 AT2 receptor 6JOD - -
TM6 233 S 6.27x27 AT2 receptor 6JOD Y1 receptor 5ZBH
TM6 234 C 6.28x28 AT2 receptor 6JOD - -
TM6 235 L 6.29x29 AT2 receptor 6JOD CB2 receptor 5ZTY
TM6 236 K 6.30x30 AT2 receptor 6JOD CXCR4 3ODU
TM6 237 Q 6.31x31 AT2 receptor 6JOD 5-HT2A receptor 6A94
TM6 238 K 6.32x32 AT2 receptor 6JOD CXCR4 3ODU
TM6 239 A 6.33x33 AT2 receptor 6JOD CXCR4 3ODU
TM6 240 R 6.34x34 AT2 receptor 6JOD - -
TM6 241 R 6.35x35 CCR7 6QZH CCR5 5UIW
TM6 242 L 6.36x36 CCR7 6QZH CCR5 5UIW
TM6 243 T 6.37x37 CCR7 6QZH CXCR4 3ODU
TM6 244 I 6.38x38 CCR7 6QZH CCR7 6QZH
TM6 245 L 6.39x39 CCR7 6QZH CB1 receptor 5TGZ
TM6 246 L 6.40x40 CCR7 6QZH CXCR4 3ODU
TM6 247 L 6.41x41 CCR7 6QZH CCR9 5LWE
TM6 248 L 6.42x42 CCR7 6QZH CXCR4 3ODU
TM6 249 A 6.43x43 CCR7 6QZH CXCR4 3ODU
TM6 250 F 6.44x44 CCR7 6QZH CCR7 6QZH
TM6 251 Y 6.45x45 CCR7 6QZH PAR2 5NDD
TM6 252 V 6.46x46 CCR7 6QZH CCR7 6QZH
TM6 253 C 6.47x47 CCR7 6QZH CXCR4 3ODU
TM6 254 F 6.48x48 CCR7 6QZH MT2 receptor 6ME6
TM6 255 L 6.49x49 CCR7 6QZH CCR7 6QZH
TM6 256 P 6.50x50 CCR7 6QZH CCR7 6QZH
TM6 257 F 6.51x51 CCR7 6QZH ghrelin receptor 6KO5
TM6 258 H 6.52x52 CCR7 6QZH NTS1 receptor 4BUO
TM6 259 I 6.53x53 CCR7 6QZH CCR5 5UIW
TM6 260 L 6.54x54 CCR7 6QZH OX2 receptor 5WS3
TM6 261 R 6.55x55 CCR7 6QZH NTS1 receptor 4BUO
TM6 262 V 6.56x56 CCR7 6QZH OX2 receptor 5WS3
TM6 263 I 6.57x57 CCR7 6QZH CXCR4 3ODU
TM6 264 R 6.58x58 CCR7 6QZH succinate receptor 6RNK
TM6 265 I 6.59x59 P2Y1 receptor 4XNW D2 receptor 6CM4
TM6 266 E 6.60x60 P2Y1 receptor 4XNW - -
TM6 267 S 6.61x61 P2Y1 receptor 4XNW ghrelin receptor 6KO5
ECL3 268 R - - - -
ECL3 269 L NTS1 receptor 4BUO - -
ECL3 270 L NTS1 receptor 4BUO - -
ECL3 271 S NTS1 receptor 4BUO - -
ECL3 272 I - - - -
TM7 273 S 7.24x23 P2Y1 receptor 4XNW - -
TM7 274 C 7.25x24 CCR7 6QZH CCR7 6QZH
TM7 275 S 7.26x25 CCR7 6QZH CCR5 5UIW
TM7 276 I 7.27x26 CCR7 6QZH AT1 receptor 4ZUD
TM7 277 E 7.28x27 CCR7 6QZH CXCR4 3ODU
TM7 278 N 7.29x28 CCR7 6QZH CCR5 5UIW
TM7 279 Q 7.30x29 CCR7 6QZH CCR7 6QZH
TM7 280 I 7.31x30 CCR7 6QZH CCR9 5LWE
TM7 281 H 7.32x31 CCR7 6QZH CXCR4 3ODU
TM7 282 E 7.33x32 CCR7 6QZH β2-adrenoceptor 2RH1
TM7 283 A 7.34x33 CCR7 6QZH CCR7 6QZH
TM7 284 Y 7.35x34 CCR7 6QZH CCR7 6QZH
TM7 285 I 7.36x35 CCR7 6QZH β2-adrenoceptor 5JQH
TM7 286 V 7.37x36 CCR7 6QZH CCR7 6QZH
TM7 287 S 7.38x37 CCR7 6QZH OX2 receptor 5WS3
TM7 288 R 7.39x38 CCR7 6QZH P2Y1 receptor 4XNW
TM7 289 P 7.40x39 CCR7 6QZH succinate receptor 6RNK
TM7 290 L 7.41x40 CCR7 6QZH CCR7 6QZH
TM7 291 A 7.42x41 CCR7 6QZH CCR7 6QZH
TM7 292 A 7.43x42 CCR7 6QZH CysLT2 receptor 6RZ6
TM7 293 L 7.44x43 CCR7 6QZH CXCR2 6LFL
TM7 294 N 7.45x45 CCR7 6QZH apelin receptor 5VBL
TM7 295 T 7.46x46 CCR7 6QZH Y1 receptor 5ZBH
TM7 296 F 7.47x47 CCR7 6QZH GPR52 6LI1
TM7 297 G 7.48x48 CCR7 6QZH - -
TM7 298 N 7.49x49 CCR7 6QZH CCR7 6QZH
TM7 299 L 7.50x50 CCR7 6QZH - -
TM7 300 L 7.51x51 CCR7 6QZH CXCR2 6LFL
TM7 301 L 7.52x52 CCR7 6QZH CCR7 6QZH
TM7 302 Y 7.53x53 CCR7 6QZH CCR7 6QZH
TM7 303 V 7.54x54 CCR7 6QZH CCR9 5LWE
TM7 304 V 7.55x55 CCR7 6QZH C5a1 receptor 5O9H
TM7 305 V 7.56x56 CysLT2 receptor 6RZ6 CCR5 5UIW
H8 306 S 8.47x47 PAR2 5NDD PAR2 5NDD
H8 307 D 8.48x48 PAR2 5NDD NK1 receptor 6HLP
H8 308 N 8.49x49 CCR7 6QZH NTS1 receptor 4BUO
H8 309 F 8.50x50 CCR7 6QZH CCR7 6QZH
H8 310 Q 8.51x51 CCR7 6QZH Y1 receptor 5ZBH
H8 311 Q 8.52x52 CCR7 6QZH NTS1 receptor 4BUO
H8 312 A 8.53x53 CCR7 6QZH apelin receptor 5VBL
H8 313 V 8.54x54 CCR7 6QZH ghrelin receptor 6KO5
H8 314 C 8.55x55 CCR7 6QZH - -
H8 315 S 8.56x56 CCR7 6QZH NTS1 receptor 4BUO
H8 316 T 8.57x57 CCR7 6QZH CCR9 5LWE
H8 317 V 8.58x58 CCR7 6QZH - -
H8 318 R 8.59x59 CysLT2 receptor 6RZ6 DP2 receptor 6D27
C-term 319 C - - - -
C-term 320 K - - - -
C-term 321 V - - - -
C-term 322 S - - - -
C-term 323 G - - - -