CysLT2 receptor homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Inactive
VERSION
2021-04-08
MODEL
TEMPLATES
6RZ6 (CysLT2 receptor)
4MBS (CCR5)
6RZ4 (CysLT1 receptor)
6RZ5 (CysLT1 receptor)
5UNG (AT2 receptor)
None
4MBS (CCR5)
6RZ4 (CysLT1 receptor)
6RZ5 (CysLT1 receptor)
5UNG (AT2 receptor)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 84.4 | 8.9 | 6.6 |
| Side-chains | 22.8 | 63.2 | 13.9 |
Number of backbone templates: 5
Number of rotamer templates: 44
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 26 | N | - | - | - | - | - |
| N-term | 27 | N | - | - | - | - | - |
| N-term | 28 | S | - | - | - | - | - |
| N-term | 29 | R | - | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| N-term | 30 | N | - | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| TM1 | 31 | C | 1.25x25 | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| TM1 | 32 | T | 1.26x26 | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| TM1 | 33 | I | 1.27x27 | CCR5 | 4MBS | ETB receptor | 5X93 |
| TM1 | 34 | E | 1.28x28 | CCR5 | 4MBS | M4 receptor | 5DSG |
| TM1 | 35 | N | 1.29x29 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM1 | 36 | F | 1.30x30 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM1 | 37 | K | 1.31x31 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM1 | 38 | R | 1.32x32 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM1 | 39 | E | 1.33x33 | CCR5 | 4MBS | CysLT2 receptor | 6RZ7 |
| TM1 | 40 | F | 1.34x34 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM1 | 41 | F | 1.35x35 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM1 | 42 | P | 1.36x36 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 43 | I | 1.37x37 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM1 | 44 | V | 1.38x38 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM1 | 45 | Y | 1.39x39 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 46 | L | 1.40x40 | CCR5 | 4MBS | NOP receptor | 5DHG |
| TM1 | 47 | I | 1.41x41 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM1 | 48 | I | 1.42x42 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM1 | 49 | F | 1.43x43 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 50 | F | 1.44x44 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM1 | 51 | W | 1.45x45 | CCR5 | 4MBS | - | - |
| TM1 | 52 | G | 1.46x46 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 53 | V | 1.47x47 | CCR5 | 4MBS | C5a1 receptor | 6C1Q |
| TM1 | 54 | L | 1.48x48 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM1 | 55 | G | 1.49x49 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 56 | N | 1.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 57 | G | 1.51x51 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM1 | 58 | L | 1.52x52 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 59 | S | 1.53x53 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM1 | 60 | I | 1.54x54 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 61 | Y | 1.55x55 | CCR5 | 4MBS | μ receptor | 4DKL |
| TM1 | 62 | V | 1.56x56 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM1 | 63 | F | 1.57x57 | CCR5 | 4MBS | M3 receptor | 5ZHP |
| TM1 | 64 | L | 1.58x58 | CCR5 | 4MBS | CXCR2 | 6LFL |
| TM1 | 65 | Q | 1.59x59 | CCR5 | 4MBS | Rhodopsin | 1U19 |
| TM1 | 66 | P | 1.60x60 | CCR5 | 4MBS | - | - |
| ICL1 | 67 | Y | - | - | - | - | - |
| ICL1 | 68 | K | - | CysLT1 receptor | 6RZ4 | - | - |
| ICL1 | 69 | K | - | CysLT1 receptor | 6RZ4 | - | - |
| ICL1 | 70 | S | - | - | - | - | - |
| TM2 | 71 | T | 2.37x37 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM2 | 72 | S | 2.38x38 | CCR5 | 4MBS | apelin receptor | 5VBL |
| TM2 | 73 | V | 2.39x39 | CCR5 | 4MBS | DP2 receptor | 6D27 |
| TM2 | 74 | N | 2.40x40 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM2 | 75 | V | 2.41x41 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM2 | 76 | F | 2.42x42 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM2 | 77 | M | 2.43x43 | CCR5 | 4MBS | OT receptor | 6TPK |
| TM2 | 78 | L | 2.44x44 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 79 | N | 2.45x45 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 80 | L | 2.46x46 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 81 | A | 2.47x47 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 82 | I | 2.48x48 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 83 | S | 2.49x49 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 84 | D | 2.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 85 | L | 2.51x51 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 86 | L | 2.52x52 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM2 | 87 | F | 2.53x53 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 88 | I | 2.54x54 | CCR5 | 4MBS | ETB receptor | 5X93 |
| TM2 | 89 | S | 2.55x55 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM2 | 90 | T | 2.56x56 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 91 | L | 2.57x57 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM2 | 92 | P | 2.58x58 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 93 | F | 2.59x59 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 94 | R | 2.60x60 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM2 | 95 | A | 2.61x61 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 96 | D | 2.62x62 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM2 | 97 | Y | 2.63x63 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 98 | Y | 2.64x64 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM2 | 99 | L | 2.65x65 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM2 | 100 | R | 2.66x66 | CCR5 | 4MBS | - | - |
| TM2 | 101 | G | 2.67x67 | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| ECL1 | 102 | S | - | - | - | - | - |
| ECL1 | 103 | N | 23.49x49 | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| ECL1 | 104 | W | 23.50x50 | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| ECL1 | 105 | I | 23.51x51 | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| ECL1 | 106 | F | 23.52x52 | - | - | - | - |
| TM3 | 107 | G | 3.21x21 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 108 | D | 3.22x22 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM3 | 109 | L | 3.23x23 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM3 | 110 | A | 3.24x24 | CCR5 | 4MBS | C5a1 receptor | 6C1Q |
| TM3 | 111 | C | 3.25x25 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 112 | R | 3.26x26 | CCR5 | 4MBS | NTS1 receptor | 4BUO |
| TM3 | 113 | I | 3.27x27 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 114 | M | 3.28x28 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM3 | 115 | S | 3.29x29 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 116 | Y | 3.30x30 | CCR5 | 4MBS | apelin receptor | 5VBL |
| TM3 | 117 | S | 3.31x31 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 118 | L | 3.32x32 | CCR5 | 4MBS | EP4 receptor | 5YWY |
| TM3 | 119 | Y | 3.33x33 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM3 | 120 | V | 3.34x34 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM3 | 121 | N | 3.35x35 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM3 | 122 | M | 3.36x36 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM3 | 123 | Y | 3.37x37 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM3 | 124 | S | 3.38x38 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 125 | S | 3.39x39 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM3 | 126 | I | 3.40x40 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 127 | Y | 3.41x41 | CCR5 | 4MBS | NK1 receptor | 6HLP |
| TM3 | 128 | F | 3.42x42 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 129 | L | 3.43x43 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM3 | 130 | T | 3.44x44 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 131 | V | 3.45x45 | CCR5 | 4MBS | Rhodopsin | 1U19 |
| TM3 | 132 | L | 3.46x46 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 133 | S | 3.47x47 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM3 | 134 | V | 3.48x48 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM3 | 135 | V | 3.49x49 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM3 | 136 | R | 3.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 137 | F | 3.51x51 | CCR5 | 4MBS | C5a1 receptor | 6C1Q |
| TM3 | 138 | L | 3.52x52 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 139 | A | 3.53x53 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 140 | M | 3.54x54 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM3 | 141 | V | 3.55x55 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 142 | H | 3.56x56 | CCR5 | 4MBS | CCR5 | 4MBS |
| ICL2 | 143 | P | 34.50x50 | - | - | - | - |
| ICL2 | 144 | F | 34.51x51 | CysLT1 receptor | 6RZ5 | - | - |
| ICL2 | 145 | R | 34.52x52 | CysLT1 receptor | 6RZ5 | CCR9 | 5LWE |
| ICL2 | 146 | L | 34.53x53 | CysLT1 receptor | 6RZ5 | - | - |
| ICL2 | 147 | L | 34.54x54 | CysLT1 receptor | 6RZ5 | CCR5 | 4MBS |
| ICL2 | 148 | H | 34.55x55 | CysLT1 receptor | 6RZ5 | D3 receptor | 3PBL |
| ICL2 | 149 | V | 34.56x56 | CysLT1 receptor | 6RZ5 | BLT1 receptor | 5X33 |
| ICL2 | 150 | T | 34.57x57 | - | - | - | - |
| TM4 | 151 | S | 4.38x38 | CCR5 | 4MBS | NTS1 receptor | 4BUO |
| TM4 | 152 | I | 4.39x39 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM4 | 153 | R | 4.40x40 | CCR5 | 4MBS | μ receptor | 4DKL |
| TM4 | 154 | S | 4.41x41 | CCR5 | 4MBS | apelin receptor | 5VBL |
| TM4 | 155 | A | 4.42x42 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM4 | 156 | W | 4.43x43 | CCR5 | 4MBS | C5a1 receptor | 6C1Q |
| TM4 | 157 | I | 4.44x44 | CCR5 | 4MBS | μ receptor | 4DKL |
| TM4 | 158 | L | 4.45x45 | CCR5 | 4MBS | C5a1 receptor | 5O9H |
| TM4 | 159 | C | 4.46x46 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM4 | 160 | G | 4.47x47 | CCR5 | 4MBS | Y2 receptor | 7DDZ |
| TM4 | 161 | I | 4.48x48 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM4 | 162 | I | 4.49x49 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM4 | 163 | W | 4.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM4 | 164 | I | 4.51x51 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM4 | 165 | L | 4.52x52 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM4 | 166 | I | 4.53x53 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM4 | 167 | M | 4.54x54 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM4 | 168 | A | 4.55x55 | CCR5 | 4MBS | μ receptor | 4DKL |
| TM4 | 169 | S | 4.56x56 | CCR5 | 4MBS | ghrelin receptor | 6KO5 |
| TM4 | 170 | S | 4.57x57 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM4 | 171 | I | 4.58x59 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM4 | 172 | M | 4.59x60 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM4 | 173 | L | 4.60x61 | CCR5 | 4MBS | Rhodopsin | 1U19 |
| TM4 | 174 | L | 4.61x62 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM4 | 175 | D | 4.62x63 | CCR5 | 4MBS | CysLT2 receptor | 6RZ8 |
| TM4 | 176 | S | 4.63x64 | CCR5 | 4MBS | D1 receptor | 7CKZ |
| ECL2 | 177 | G | - | CCR5 | 4MBS | - | - |
| ECL2 | 178 | S | - | CCR5 | 4MBS | CCR5 | 4MBS |
| ECL2 | 179 | E | - | CCR5 | 4MBS | - | - |
| ECL2 | 180 | Q | - | CCR5 | 4MBS | - | - |
| ECL2 | 181 | N | - | CCR5 | 4MBS | - | - |
| ECL2 | 182 | G | - | CCR5 | 4MBS | CCR5 | 4MBS |
| ECL2 | 183 | S | - | CCR5 | 4MBS | - | - |
| ECL2 | 184 | V | - | CCR5 | 4MBS | - | - |
| ECL2 | 185 | T | - | CCR5 | 4MBS | - | - |
| ECL2 | 186 | S | - | CCR5 | 4MBS | - | - |
| ECL2 | 187 | C | 45.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| ECL2 | 188 | L | 45.51x51 | CCR5 | 4MBS | NOP receptor | 5DHG |
| ECL2 | 189 | E | 45.52x52 | CCR5 | 4MBS | CXCR2 | 6LFL |
| ECL2 | 190 | L | - | CCR5 | 4MBS | - | - |
| ECL2 | 191 | N | - | CCR5 | 4MBS | - | - |
| ECL2 | 192 | L | - | CCR5 | 4MBS | - | - |
| ECL2 | 193 | Y | - | CCR5 | 4MBS | CCR5 | 4MBS |
| ECL2 | 194 | K | - | CCR5 | 4MBS | - | - |
| TM5 | 195 | I | 5.32x33 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM5 | 196 | A | 5.33x34 | CCR5 | 4MBS | apelin receptor | 5VBL |
| TM5 | 197 | K | 5.34x35 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM5 | 198 | L | 5.35x36 | CCR5 | 4MBS | ghrelin receptor | 6KO5 |
| TM5 | 199 | Q | 5.36x37 | CCR5 | 4MBS | β2-adrenoceptor | 2RH1 |
| TM5 | 200 | T | 5.37x38 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM5 | 201 | M | 5.38x39 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM5 | 202 | N | 5.39x40 | CCR5 | 4MBS | GnRH1 receptor | 7BR3 |
| TM5 | 203 | Y | 5.40x41 | CCR5 | 4MBS | EP4 receptor | 5YWY |
| TM5 | 204 | I | 5.41x42 | CCR5 | 4MBS | 5-HT2A receptor | 6A94 |
| TM5 | 205 | A | 5.42x43 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM5 | 206 | L | 5.43x44 | CCR5 | 4MBS | C5a1 receptor | 6C1Q |
| TM5 | 207 | V | 5.44x45 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM5 | 208 | V | 5.45x46 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM5 | 209 | G | 5.46x461 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 210 | C | 5.47x47 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM5 | 211 | L | 5.48x48 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM5 | 212 | L | 5.49x49 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 213 | P | 5.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 214 | F | 5.51x51 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM5 | 215 | F | 5.52x52 | CCR5 | 4MBS | ghrelin receptor | 6KO5 |
| TM5 | 216 | T | 5.53x53 | CCR5 | 4MBS | C5a1 receptor | 6C1Q |
| TM5 | 217 | L | 5.54x54 | CCR5 | 4MBS | ghrelin receptor | 6KO5 |
| TM5 | 218 | S | 5.55x55 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM5 | 219 | I | 5.56x56 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 220 | C | 5.57x57 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 221 | Y | 5.58x58 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 222 | L | 5.59x59 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM5 | 223 | L | 5.60x60 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM5 | 224 | I | 5.61x61 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 225 | I | 5.62x62 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM5 | 226 | R | 5.63x63 | CCR5 | 4MBS | CCR2 | 5T1A |
| TM5 | 227 | V | 5.64x64 | CCR5 | 4MBS | D3 receptor | 3PBL |
| TM5 | 228 | L | 5.65x65 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 229 | L | 5.66x66 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 230 | K | 5.67x67 | CCR5 | 4MBS | CXCR2 | 6LFL |
| TM5 | 231 | V | 5.68x68 | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| ICL3 | 232 | E | - | - | - | - | - |
| ICL3 | 233 | V | - | - | - | - | - |
| ICL3 | 234 | P | - | - | - | - | - |
| ICL3 | 235 | E | - | - | - | - | - |
| TM6 | 236 | S | 6.24x25 | AT2 receptor | 5UNG | A1 receptor | 5UEN |
| TM6 | 237 | G | 6.25x26 | AT2 receptor | 5UNG | - | - |
| TM6 | 238 | L | 6.26x27 | AT2 receptor | 5UNG | ETB receptor | 5X93 |
| TM6 | 239 | R | 6.27x28 | CCR5 | 4MBS | CB2 receptor | 6PT0 |
| TM6 | 240 | V | 6.28x29 | CCR5 | 4MBS | - | - |
| TM6 | 241 | S | 6.29x30 | CCR5 | 4MBS | C5a1 receptor | 6C1Q |
| TM6 | 242 | H | 6.30x31 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 243 | R | 6.31x32 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 244 | K | 6.32x33 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM6 | 245 | A | 6.33x34 | CCR5 | 4MBS | ETB receptor | 5X93 |
| TM6 | 246 | L | 6.34x35 | CCR5 | 4MBS | NTS1 receptor | 4BUO |
| TM6 | 247 | T | 6.35x36 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM6 | 248 | T | 6.36x37 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM6 | 249 | I | 6.37x38 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM6 | 250 | I | 6.38x39 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM6 | 251 | I | 6.39x40 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 252 | T | 6.40x41 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM6 | 253 | L | 6.41x42 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM6 | 254 | I | 6.42x43 | CCR5 | 4MBS | CXCR2 | 6LFL |
| TM6 | 255 | I | 6.43x44 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM6 | 256 | F | 6.44x45 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 257 | F | 6.45x46 | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| TM6 | 258 | L | 6.46x461 | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| TM6 | 259 | C | 6.47x47 | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| TM6 | 260 | F | 6.48x48 | CCR5 | 4MBS | MT1 receptor | 6ME2 |
| TM6 | 261 | L | 6.49x49 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM6 | 262 | P | 6.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 263 | Y | 6.51x51 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 264 | H | 6.52x52 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM6 | 265 | T | 6.53x53 | CCR5 | 4MBS | Rhodopsin | 6I9K |
| TM6 | 266 | L | 6.54x54 | CCR5 | 4MBS | OX1 receptor | 6TO7 |
| TM6 | 267 | R | 6.55x55 | CCR5 | 4MBS | ghrelin receptor | 6KO5 |
| TM6 | 268 | T | 6.56x56 | CCR5 | 4MBS | apelin receptor | 5VBL |
| TM6 | 269 | V | 6.57x57 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM6 | 270 | H | 6.58x58 | CCR5 | 4MBS | β2-adrenoceptor | 2RH1 |
| TM6 | 271 | L | 6.59x59 | CCR5 | 4MBS | ETB receptor | 5X93 |
| TM6 | 272 | T | 6.60x60 | CCR5 | 4MBS | ETB receptor | 5X93 |
| TM6 | 273 | T | 6.61x61 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM6 | 274 | W | 6.62x62 | CCR5 | 4MBS | AT2 receptor | 5UNG |
| ECL3 | 275 | K | - | - | - | - | - |
| ECL3 | 276 | V | - | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| ECL3 | 277 | G | - | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| ECL3 | 278 | L | - | CysLT2 receptor | 6RZ6 | CysLT2 receptor | 6RZ6 |
| ECL3 | 279 | C | - | - | - | - | - |
| TM7 | 280 | K | 7.28x27 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM7 | 281 | D | 7.29x28 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM7 | 282 | R | 7.30x29 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 283 | L | 7.31x30 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 284 | H | 7.32x31 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM7 | 285 | K | 7.33x32 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM7 | 286 | A | 7.34x33 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 287 | L | 7.35x34 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM7 | 288 | V | 7.36x35 | CCR5 | 4MBS | MT1 receptor | 6ME2 |
| TM7 | 289 | I | 7.37x36 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM7 | 290 | T | 7.38x37 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 291 | L | 7.39x38 | CCR5 | 4MBS | S1P1 receptor | 3V2Y |
| TM7 | 292 | A | 7.40x39 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM7 | 293 | L | 7.41x40 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 294 | A | 7.42x41 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM7 | 295 | A | 7.43x42 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM7 | 296 | A | 7.44x43 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM7 | 297 | N | 7.45x45 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM7 | 298 | A | 7.46x46 | CCR5 | 4MBS | ghrelin receptor | 6KO5 |
| TM7 | 299 | C | 7.47x47 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 300 | F | 7.48x48 | CCR5 | 4MBS | β2-adrenoceptor | 2RH1 |
| TM7 | 301 | N | 7.49x49 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 302 | P | 7.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 303 | L | 7.51x51 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM7 | 304 | L | 7.52x52 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM7 | 305 | Y | 7.53x53 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 306 | Y | 7.54x54 | CCR5 | 4MBS | ETB receptor | 5X93 |
| TM7 | 307 | F | 7.55x55 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 308 | A | 7.56x56 | CCR5 | 4MBS | C5a1 receptor | 6C1Q |
| H8 | 309 | G | 8.47x47 | CCR5 | 4MBS | CCR5 | 4MBS |
| H8 | 310 | E | 8.48x48 | CCR5 | 4MBS | CCR5 | 4MBS |
| H8 | 311 | N | 8.49x49 | CCR5 | 4MBS | δ receptor | 4N6H |
| H8 | 312 | F | 8.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| H8 | 313 | K | 8.51x51 | CCR5 | 4MBS | μ receptor | 4DKL |
| H8 | 314 | D | 8.52x52 | CCR5 | 4MBS | M1 receptor | 6WJC |
| H8 | 315 | R | 8.53x53 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| H8 | 316 | L | 8.54x54 | CCR5 | 4MBS | CCR5 | 5UIW |
| H8 | 317 | K | 8.55x55 | CCR5 | 4MBS | ETB receptor | 5X93 |
| H8 | 318 | S | 8.56x56 | CCR5 | 4MBS | apelin receptor | 5VBL |
| H8 | 319 | A | 8.57x57 | CCR5 | 4MBS | ETB receptor | 5X93 |
| H8 | 320 | L | 8.58x58 | CCR5 | 4MBS | apelin receptor | 5VBL |
| H8 | 321 | R | 8.59x59 | CCR5 | 4MBS | A2A receptor | 3QAK |
| H8 | 322 | K | 8.60x60 | CysLT2 receptor | 6RZ6 | - | - |
| C-term | 323 | G | - | - | - | - | - |
| C-term | 324 | H | - | - | - | - | - |
| C-term | 325 | P | - | - | - | - | - |
| C-term | 326 | Q | - | - | - | - | - |
| C-term | 327 | K | - | - | - | - | - |