GPR42 homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Inactive
VERSION
2021-09-08
MODEL
TEMPLATES
5NDD (PAR2)
5VBL (apelin receptor)
5TZY (FFA1 receptor)
6RZ6 (CysLT2 receptor)
5LWE (CCR9)
None
5VBL (apelin receptor)
5TZY (FFA1 receptor)
6RZ6 (CysLT2 receptor)
5LWE (CCR9)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 89.5 | 6.1 | 4.4 |
| Side-chains | 26.9 | 57.8 | 15.3 |
Number of backbone templates: 5
Number of rotamer templates: 46
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 6 | D | - | PAR2 | 5NDD | PAR2 | 5NDD |
| N-term | 7 | Q | - | PAR2 | 5NDD | PAR2 | 5NDD |
| N-term | 8 | S | - | PAR2 | 5NDD | PAR2 | 5NDD |
| N-term | 9 | Y | - | PAR2 | 5NDD | PAR2 | 5NDD |
| N-term | 10 | F | - | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 11 | S | 1.29x29 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM1 | 12 | G | 1.30x30 | PAR2 | 5NDD | NOP receptor | 5DHG |
| TM1 | 13 | N | 1.31x31 | PAR2 | 5NDD | CXCR2 | 6LFL |
| TM1 | 14 | H | 1.32x32 | PAR2 | 5NDD | Rhodopsin | 6I9K |
| TM1 | 15 | W | 1.33x33 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM1 | 16 | F | 1.34x34 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 17 | V | 1.35x35 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM1 | 18 | F | 1.36x36 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM1 | 19 | S | 1.37x37 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM1 | 20 | V | 1.38x38 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 21 | Y | 1.39x39 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 22 | L | 1.40x40 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM1 | 23 | L | 1.41x41 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM1 | 24 | T | 1.42x42 | PAR2 | 5NDD | MT1 receptor | 6ME2 |
| TM1 | 25 | F | 1.43x43 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 26 | L | 1.44x44 | PAR2 | 5NDD | CXCR2 | 6LFL |
| TM1 | 27 | V | 1.45x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 28 | G | 1.46x46 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM1 | 29 | L | 1.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 30 | P | 1.48x48 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 31 | L | 1.49x49 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM1 | 32 | N | 1.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 33 | L | 1.51x51 | PAR2 | 5NDD | MT1 receptor | 6ME2 |
| TM1 | 34 | L | 1.52x52 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM1 | 35 | A | 1.53x53 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 36 | L | 1.54x54 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 37 | V | 1.55x55 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM1 | 38 | V | 1.56x56 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 39 | F | 1.57x57 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM1 | 40 | V | 1.58x58 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM1 | 41 | G | 1.59x59 | PAR2 | 5NDD | TP receptor | 6IIV |
| TM1 | 42 | K | 1.60x60 | PAR2 | 5NDD | PAR1 | 3VW7 |
| ICL1 | 43 | L | - | - | - | - | - |
| ICL1 | 44 | R | - | apelin receptor | 5VBL | apelin receptor | 5VBL |
| ICL1 | 45 | C | - | apelin receptor | 5VBL | - | - |
| ICL1 | 46 | R | - | apelin receptor | 5VBL | - | - |
| ICL1 | 47 | P | - | - | - | - | - |
| TM2 | 48 | V | 2.37x37 | PAR2 | 5NDD | - | - |
| TM2 | 49 | A | 2.38x38 | PAR2 | 5NDD | μ receptor | 4DKL |
| TM2 | 50 | V | 2.39x39 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM2 | 51 | D | 2.40x40 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM2 | 52 | V | 2.41x41 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM2 | 53 | L | 2.42x42 | PAR2 | 5NDD | D3 receptor | 3PBL |
| TM2 | 54 | L | 2.43x43 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM2 | 55 | L | 2.44x44 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM2 | 56 | N | 2.45x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 57 | L | 2.46x46 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 58 | T | 2.47x47 | PAR2 | 5NDD | PAF receptor | 5ZKQ |
| TM2 | 59 | A | 2.48x48 | PAR2 | 5NDD | D4 receptor | 5WIV |
| TM2 | 60 | S | 2.49x49 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM2 | 61 | D | 2.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 62 | L | 2.51x51 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 63 | L | 2.52x52 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 64 | L | 2.53x53 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM2 | 65 | L | 2.54x54 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM2 | 66 | L | 2.55x55 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM2 | 67 | F | 2.56x56 | PAR2 | 5NDD | Rhodopsin | 6I9K |
| TM2 | 68 | L | 2.57x57 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM2 | 69 | P | 2.58x58 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM2 | 70 | F | 2.59x59 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM2 | 71 | R | 2.60x60 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM2 | 72 | M | 2.61x61 | PAR2 | 5NDD | 5-HT2A receptor | 6A94 |
| TM2 | 73 | V | 2.62x62 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM2 | 74 | E | 2.63x63 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM2 | 75 | A | 2.64x64 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM2 | 76 | A | 2.65x65 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM2 | 77 | N | 2.66x66 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| ECL1 | 78 | G | - | PAR2 | 5NDD | PAR2 | 5NDD |
| ECL1 | 79 | M | - | PAR2 | 5NDD | - | - |
| ECL1 | 80 | H | 23.49x49 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| ECL1 | 81 | W | 23.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| ECL1 | 82 | P | 23.51x51 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| ECL1 | 83 | L | 23.52x52 | PAR2 | 5NDD | DP2 receptor | 6D27 |
| TM3 | 84 | P | 3.21x21 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM3 | 85 | F | 3.22x22 | PAR2 | 5NDD | A1 receptor | 5UEN |
| TM3 | 86 | I | 3.23x23 | PAR2 | 5NDD | μ receptor | 4DKL |
| TM3 | 87 | L | 3.24x24 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 88 | C | 3.25x25 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 89 | P | 3.26x26 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM3 | 90 | L | 3.27x27 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM3 | 91 | S | 3.28x28 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM3 | 92 | G | 3.29x29 | PAR2 | 5NDD | PAF receptor | 5ZKQ |
| TM3 | 93 | F | 3.30x30 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM3 | 94 | I | 3.31x31 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM3 | 95 | F | 3.32x32 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 96 | F | 3.33x33 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM3 | 97 | T | 3.34x34 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM3 | 98 | T | 3.35x35 | PAR2 | 5NDD | P2Y12 receptor | 4NTJ |
| TM3 | 99 | I | 3.36x36 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| TM3 | 100 | Y | 3.37x37 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 101 | L | 3.38x38 | PAR2 | 5NDD | - | - |
| TM3 | 102 | T | 3.39x39 | PAR2 | 5NDD | NTS1 receptor | 4BUO |
| TM3 | 103 | A | 3.40x40 | PAR2 | 5NDD | apelin receptor | 5VBL |
| TM3 | 104 | L | 3.41x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 105 | F | 3.42x42 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 106 | L | 3.43x43 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 107 | A | 3.44x44 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM3 | 108 | A | 3.45x45 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM3 | 109 | V | 3.46x46 | PAR2 | 5NDD | NK1 receptor | 6HLP |
| TM3 | 110 | S | 3.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 111 | I | 3.48x48 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 112 | E | 3.49x49 | PAR2 | 5NDD | ghrelin receptor | 6KO5 |
| TM3 | 113 | R | 3.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM3 | 114 | F | 3.51x51 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 115 | L | 3.52x52 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 116 | S | 3.53x53 | PAR2 | 5NDD | H1 receptor | 3RZE |
| TM3 | 117 | V | 3.54x54 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM3 | 118 | A | 3.55x55 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM3 | 119 | H | 3.56x56 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| ICL2 | 120 | P | 34.50x50 | - | - | - | - |
| ICL2 | 121 | L | 34.51x51 | FFA1 receptor | 5TZY | FFA1 receptor | 5TZY |
| ICL2 | 122 | W | 34.52x52 | FFA1 receptor | 5TZY | DP2 receptor | 6D27 |
| ICL2 | 123 | Y | 34.53x53 | FFA1 receptor | 5TZY | FFA1 receptor | 5TZY |
| ICL2 | 124 | K | 34.54x54 | FFA1 receptor | 5TZY | ghrelin receptor | 6KO5 |
| ICL2 | 125 | T | 34.55x55 | FFA1 receptor | 5TZY | CCR9 | 5LWE |
| ICL2 | 126 | R | 34.56x56 | FFA1 receptor | 5TZY | P2Y1 receptor | 4XNW |
| ICL2 | 127 | P | 34.57x57 | - | - | - | - |
| TM4 | 128 | R | 4.38x38 | PAR2 | 5NDD | CCR9 | 5LWE |
| TM4 | 129 | L | 4.39x39 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM4 | 130 | G | 4.40x40 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM4 | 131 | Q | 4.41x41 | PAR2 | 5NDD | AT2 receptor | 5UNG |
| TM4 | 132 | A | 4.42x42 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 133 | G | 4.43x43 | PAR2 | 5NDD | M2 receptor | 5YC8 |
| TM4 | 134 | L | 4.44x44 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM4 | 135 | V | 4.45x45 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM4 | 136 | S | 4.46x46 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 137 | V | 4.47x47 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM4 | 138 | A | 4.48x48 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 139 | C | 4.49x49 | PAR2 | 5NDD | A1 receptor | 5UEN |
| TM4 | 140 | W | 4.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 141 | L | 4.51x51 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 142 | L | 4.52x52 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM4 | 143 | A | 4.53x53 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM4 | 144 | S | 4.54x54 | PAR2 | 5NDD | μ receptor | 4DKL |
| TM4 | 145 | A | 4.55x55 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM4 | 146 | H | 4.56x56 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM4 | 147 | C | 4.57x57 | FFA1 receptor | 5TZY | CCR9 | 5LWE |
| TM4 | 148 | S | 4.58x58 | FFA1 receptor | 5TZY | P2Y1 receptor | 4XNW |
| TM4 | 149 | V | 4.59x59 | FFA1 receptor | 5TZY | PAR1 | 3VW7 |
| TM4 | 150 | V | 4.60x60 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM4 | 151 | Y | 4.61x61 | PAR2 | 5NDD | DP2 receptor | 6D27 |
| TM4 | 152 | V | 4.62x62 | PAR2 | 5NDD | κ receptor | 4DJH |
| TM4 | 153 | I | 4.63x63 | PAR2 | 5NDD | AT1 receptor | 4ZUD |
| ECL2 | 154 | E | - | PAR2 | 5NDD | - | - |
| ECL2 | 155 | F | - | PAR2 | 5NDD | - | - |
| ECL2 | 156 | S | - | PAR2 | 5NDD | - | - |
| ECL2 | 157 | G | - | PAR2 | 5NDD | - | - |
| ECL2 | 158 | D | - | PAR2 | 5NDD | - | - |
| ECL2 | 159 | I | - | PAR2 | 5NDD | - | - |
| ECL2 | 160 | S | - | PAR2 | 5NDD | - | - |
| ECL2 | 161 | H | - | PAR2 | 5NDD | - | - |
| ECL2 | 162 | S | - | PAR2 | 5NDD | - | - |
| ECL2 | 163 | Q | - | PAR2 | 5NDD | - | - |
| ECL2 | 164 | G | - | PAR2 | 5NDD | - | - |
| ECL2 | 165 | T | - | PAR2 | 5NDD | - | - |
| ECL2 | 166 | N | - | PAR2 | 5NDD | - | - |
| ECL2 | 167 | G | - | PAR2 | 5NDD | - | - |
| ECL2 | 168 | T | - | - | - | - | - |
| ECL2 | 169 | C | 45.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| ECL2 | 170 | Y | 45.51x51 | PAR2 | 5NDD | - | - |
| ECL2 | 171 | L | 45.52x52 | PAR2 | 5NDD | α2B-adrenoceptor | 6K41 |
| ECL2 | 172 | E | - | PAR2 | 5NDD | - | - |
| ECL2 | 173 | F | - | PAR2 | 5NDD | - | - |
| ECL2 | 174 | W | - | PAR2 | 5NDD | - | - |
| ECL2 | 175 | K | - | PAR2 | 5NDD | - | - |
| ECL2 | 176 | D | - | PAR2 | 5NDD | - | - |
| ECL2 | 177 | Q | - | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 178 | L | 5.32x33 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM5 | 179 | A | 5.33x34 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM5 | 180 | I | 5.34x35 | PAR2 | 5NDD | - | - |
| TM5 | 181 | L | 5.35x36 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 182 | L | 5.36x37 | PAR2 | 5NDD | κ receptor | 4DJH |
| TM5 | 183 | P | 5.37x38 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM5 | 184 | V | 5.38x39 | PAR2 | 5NDD | LPA6 receptor | 5XSZ |
| TM5 | 185 | R | 5.39x40 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM5 | 186 | L | 5.40x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 187 | E | 5.41x42 | PAR2 | 5NDD | US28 | 5WB1 |
| TM5 | 188 | M | 5.42x43 | PAR2 | 5NDD | Rhodopsin | 1U19 |
| TM5 | 189 | A | 5.43x44 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 190 | V | 5.44x45 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM5 | 191 | V | 5.45x46 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 192 | L | 5.46x461 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM5 | 193 | F | 5.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 194 | V | 5.48x48 | PAR2 | 5NDD | κ receptor | 4DJH |
| TM5 | 195 | V | 5.49x49 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM5 | 196 | P | 5.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 197 | L | 5.51x51 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM5 | 198 | I | 5.52x52 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM5 | 199 | I | 5.53x53 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM5 | 200 | T | 5.54x54 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 201 | S | 5.55x55 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM5 | 202 | Y | 5.56x56 | PAR2 | 5NDD | Rhodopsin | 6I9K |
| TM5 | 203 | C | 5.57x57 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM5 | 204 | Y | 5.58x58 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 205 | S | 5.59x59 | PAR2 | 5NDD | NOP receptor | 5DHG |
| TM5 | 206 | R | 5.60x60 | PAR2 | 5NDD | MT1 receptor | 6ME2 |
| TM5 | 207 | L | 5.61x61 | PAR2 | 5NDD | Rhodopsin | 1GZM |
| TM5 | 208 | V | 5.62x62 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM5 | 209 | W | 5.63x63 | PAR2 | 5NDD | CB1 receptor | 5TGZ |
| TM5 | 210 | I | 5.64x64 | PAR2 | 5NDD | α2A-adrenoceptor | 6KUX |
| TM5 | 211 | L | 5.65x65 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM5 | 212 | G | 5.66x66 | CysLT2 receptor | 6RZ6 | - | - |
| TM5 | 213 | R | 5.67x67 | CysLT2 receptor | 6RZ6 | FFA1 receptor | 5TZR |
| TM5 | 214 | G | 5.68x68 | CysLT2 receptor | 6RZ6 | CCK1 receptor | 7MBX |
| ICL3 | 215 | G | - | - | - | - | - |
| ICL3 | 216 | S | - | - | - | - | - |
| ICL3 | 217 | H | - | - | - | - | - |
| TM6 | 218 | R | 6.28x29 | PAR2 | 5NDD | FFA1 receptor | 5TZR |
| TM6 | 219 | R | 6.29x30 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM6 | 220 | Q | 6.30x31 | PAR2 | 5NDD | 5-HT2A receptor | 6A94 |
| TM6 | 221 | R | 6.31x32 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM6 | 222 | R | 6.32x33 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 223 | V | 6.33x34 | PAR2 | 5NDD | DP2 receptor | 6D27 |
| TM6 | 224 | A | 6.34x35 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM6 | 225 | G | 6.35x36 | PAR2 | 5NDD | CysLT1 receptor | 6RZ4 |
| TM6 | 226 | L | 6.36x37 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 227 | V | 6.37x38 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM6 | 228 | A | 6.38x39 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM6 | 229 | A | 6.39x40 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM6 | 230 | T | 6.40x41 | PAR2 | 5NDD | CysLT2 receptor | 6RZ6 |
| TM6 | 231 | L | 6.41x42 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM6 | 232 | L | 6.42x43 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM6 | 233 | N | 6.43x44 | PAR2 | 5NDD | - | - |
| TM6 | 234 | F | 6.44x45 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM6 | 235 | L | 6.45x46 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 236 | V | 6.46x461 | PAR2 | 5NDD | P2Y1 receptor | 4XNW |
| TM6 | 237 | C | 6.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 238 | F | 6.48x48 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 239 | G | 6.49x49 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM6 | 240 | P | 6.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 241 | Y | 6.51x51 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM6 | 242 | N | 6.52x52 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 243 | V | 6.53x53 | PAR2 | 5NDD | PAR1 | 3VW7 |
| TM6 | 244 | S | 6.54x54 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM6 | 245 | H | 6.55x55 | PAR2 | 5NDD | D3 receptor | 3PBL |
| TM6 | 246 | V | 6.56x56 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 247 | V | 6.57x57 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 248 | G | 6.58x58 | PAR2 | 5NDD | Rhodopsin | 6I9K |
| TM6 | 249 | Y | 6.59x59 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM6 | 250 | I | 6.60x60 | PAR2 | 5NDD | CCR9 | 5LWE |
| TM6 | 251 | C | 6.61x61 | PAR2 | 5NDD | D2 receptor | 6CM4 |
| ECL3 | 252 | G | - | PAR2 | 5NDD | PAR2 | 5NDD |
| ECL3 | 253 | E | - | PAR2 | 5NDD | - | - |
| ECL3 | 254 | S | - | PAR2 | 5NDD | PAR2 | 5NDD |
| ECL3 | 255 | P | - | PAR2 | 5NDD | - | - |
| TM7 | 256 | V | 7.33x32 | PAR2 | 5NDD | μ receptor | 4DKL |
| TM7 | 257 | W | 7.34x33 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM7 | 258 | R | 7.35x34 | PAR2 | 5NDD | FFA1 receptor | 5TZY |
| TM7 | 259 | I | 7.36x35 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 260 | Y | 7.37x36 | PAR2 | 5NDD | apelin receptor | 5VBL |
| TM7 | 261 | V | 7.38x37 | PAR2 | 5NDD | DP2 receptor | 6D27 |
| TM7 | 262 | T | 7.39x38 | PAR2 | 5NDD | NOP receptor | 5DHG |
| TM7 | 263 | L | 7.40x39 | PAR2 | 5NDD | MT2 receptor | 6ME7 |
| TM7 | 264 | L | 7.41x40 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 265 | S | 7.42x41 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 266 | T | 7.43x42 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 267 | L | 7.44x43 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 268 | N | 7.45x45 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 269 | S | 7.46x46 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 270 | C | 7.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 271 | V | 7.48x48 | PAR2 | 5NDD | CCR7 | 6QZH |
| TM7 | 272 | D | 7.49x49 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 273 | P | 7.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 274 | F | 7.51x51 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 275 | V | 7.52x52 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 276 | Y | 7.53x53 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 277 | Y | 7.54x54 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 278 | F | 7.55x55 | PAR2 | 5NDD | PAR2 | 5NDD |
| TM7 | 279 | S | 7.56x56 | PAR2 | 5NDD | Rhodopsin | 6I9K |
| H8 | 280 | S | 8.47x47 | PAR2 | 5NDD | PAR2 | 5NDD |
| H8 | 281 | S | 8.48x48 | PAR2 | 5NDD | Y2 receptor | 7DDZ |
| H8 | 282 | G | 8.49x49 | PAR2 | 5NDD | - | - |
| H8 | 283 | F | 8.50x50 | PAR2 | 5NDD | PAR2 | 5NDD |
| H8 | 284 | Q | 8.51x51 | PAR2 | 5NDD | Y1 receptor | 5ZBH |
| H8 | 285 | A | 8.52x52 | PAR2 | 5NDD | NOP receptor | 5DHG |
| H8 | 286 | D | 8.53x53 | PAR2 | 5NDD | CCR7 | 6QZH |
| H8 | 287 | F | 8.54x54 | PAR2 | 5NDD | μ receptor | 4DKL |
| H8 | 288 | H | 8.55x55 | PAR2 | 5NDD | CB2 receptor | 5ZTY |
| H8 | 289 | E | 8.56x56 | PAR2 | 5NDD | EP4 receptor | 5YWY |
| H8 | 290 | L | 8.57x57 | PAR2 | 5NDD | δ receptor | 4N6H |
| H8 | 291 | L | 8.58x58 | PAR2 | 5NDD | PAR2 | 5NDD |
| H8 | 292 | R | 8.59x59 | CCR9 | 5LWE | DP2 receptor | 6D27 |
| H8 | 293 | R | 8.60x60 | CCR9 | 5LWE | - | - |
| H8 | 294 | L | 8.61x61 | CCR9 | 5LWE | CCR9 | 5LWE |
| C-term | 295 | C | - | - | - | - | - |
| C-term | 296 | G | - | - | - | - | - |
| C-term | 297 | L | - | - | - | - | - |
| C-term | 298 | W | - | - | - | - | - |
| C-term | 299 | G | - | - | - | - | - |