MRGPRF homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Active
VERSION
2021-06-10
MODEL
TEMPLATES
6WWZ (CCR6)
5O9H (C5a1 receptor)
4ZUD (AT1 receptor)
6DO1 (AT1 receptor)
4XNW (P2Y1 receptor)
None
5O9H (C5a1 receptor)
4ZUD (AT1 receptor)
6DO1 (AT1 receptor)
4XNW (P2Y1 receptor)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 87.3 | 3.5 | 9.2 |
| Side-chains | 19.7 | 59.5 | 20.8 |
Number of backbone templates: 5
Number of rotamer templates: 48
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 32 | F | - | CCR6 | 6WWZ | CCR6 | 6WWZ |
| N-term | 33 | L | - | CCR6 | 6WWZ | CCR6 | 6WWZ |
| N-term | 34 | T | - | CCR6 | 6WWZ | CCR6 | 6WWZ |
| N-term | 35 | I | - | CCR6 | 6WWZ | CCR6 | 6WWZ |
| N-term | 36 | E | - | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 37 | Q | 1.25x25 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 38 | I | 1.26x26 | CCR6 | 6WWZ | - | - |
| TM1 | 39 | A | 1.27x27 | CCR6 | 6WWZ | β2-adrenoceptor | 6N48 |
| TM1 | 40 | M | 1.28x28 | CCR6 | 6WWZ | - | - |
| TM1 | 41 | L | 1.29x29 | CCR6 | 6WWZ | δ receptor | 6PT2 |
| TM1 | 42 | P | 1.30x30 | CCR6 | 6WWZ | 5-HT1B receptor | 6G79 |
| TM1 | 43 | P | 1.31x31 | CCR6 | 6WWZ | C5a1 receptor | 6C1Q |
| TM1 | 44 | P | 1.32x32 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM1 | 45 | A | 1.33x33 | CCR6 | 6WWZ | A1 receptor | 6D9H |
| TM1 | 46 | V | 1.34x34 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM1 | 47 | M | 1.35x35 | CCR6 | 6WWZ | β1-adrenoceptor | 7BU7 |
| TM1 | 48 | N | 1.36x36 | CCR6 | 6WWZ | - | - |
| TM1 | 49 | Y | 1.37x37 | CCR6 | 6WWZ | - | - |
| TM1 | 50 | I | 1.38x38 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM1 | 51 | F | 1.39x39 | CCR6 | 6WWZ | MC4 receptor | 7AUE |
| TM1 | 52 | L | 1.40x40 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM1 | 53 | L | 1.41x41 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 54 | L | 1.42x42 | CCR6 | 6WWZ | MC4 receptor | 7AUE |
| TM1 | 55 | C | 1.43x43 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 56 | L | 1.44x44 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM1 | 57 | C | 1.45x45 | CCR6 | 6WWZ | 5-HT1A receptor | 7E2X |
| TM1 | 58 | G | 1.46x46 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 59 | L | 1.47x47 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 60 | V | 1.48x48 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM1 | 61 | G | 1.49x49 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 62 | N | 1.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 63 | G | 1.51x51 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| TM1 | 64 | L | 1.52x52 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 65 | V | 1.53x53 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 66 | L | 1.54x54 | CCR6 | 6WWZ | M1 receptor | 6OIJ |
| TM1 | 67 | W | 1.55x55 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| TM1 | 68 | F | 1.56x56 | CCR6 | 6WWZ | - | - |
| TM1 | 69 | F | 1.57x57 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 70 | G | 1.58x58 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| TM1 | 71 | F | 1.59x59 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 72 | S | 1.60x60 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| ICL1 | 73 | I | - | - | - | - | - |
| ICL1 | 74 | K | - | C5a1 receptor | 5O9H | C5a1 receptor | 5O9H |
| ICL1 | 75 | R | - | - | - | - | - |
| TM2 | 76 | N | 2.37x37 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM2 | 77 | P | 2.38x38 | CCR6 | 6WWZ | 5-ht1E receptor | 7E33 |
| TM2 | 78 | F | 2.39x39 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM2 | 79 | S | 2.40x40 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM2 | 80 | I | 2.41x41 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| TM2 | 81 | Y | 2.42x42 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 82 | F | 2.43x43 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM2 | 83 | L | 2.44x44 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 84 | H | 2.45x45 | CCR6 | 6WWZ | V2 receptor | 7KH0 |
| TM2 | 85 | L | 2.46x46 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM2 | 86 | A | 2.47x47 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 87 | S | 2.48x48 | CCR6 | 6WWZ | β1-adrenoceptor | 7BU7 |
| TM2 | 88 | A | 2.49x49 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 89 | D | 2.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 90 | V | 2.51x51 | CCR6 | 6WWZ | A1 receptor | 6D9H |
| TM2 | 91 | G | 2.52x52 | CCR6 | 6WWZ | Rhodopsin | 6I9K |
| TM2 | 92 | Y | 2.53x53 | CCR6 | 6WWZ | P2Y1 receptor | 4XNW |
| TM2 | 93 | L | 2.54x54 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM2 | 94 | F | 2.55x55 | CCR6 | 6WWZ | Rhodopsin | 4X1H |
| TM2 | 95 | S | 2.56x56 | CCR6 | 6WWZ | MC4 receptor | 7AUE |
| TM2 | 96 | K | 2.57x57 | CCR6 | 6WWZ | - | - |
| TM2 | 97 | A | 2.58x58 | CCR6 | 6WWZ | CB2 receptor | 6PT0 |
| TM2 | 98 | V | 2.59x59 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM2 | 99 | F | 2.60x60 | CCR6 | 6WWZ | DP2 receptor | 6D27 |
| TM2 | 100 | S | 2.61x61 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM2 | 101 | I | 2.62x62 | CCR6 | 6WWZ | MC4 receptor | 7AUE |
| TM2 | 102 | L | 2.63x63 | CCR6 | 6WWZ | D3 receptor | 7CMV |
| TM2 | 103 | N | 2.64x64 | CCR6 | 6WWZ | A1 receptor | 6D9H |
| TM2 | 104 | T | 2.65x65 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM2 | 105 | G | 2.66x66 | CCR6 | 6WWZ | A2A receptor | 3QAK |
| TM2 | 106 | G | 2.67x67 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| ECL1 | 107 | F | - | - | - | - | - |
| ECL1 | 108 | L | - | AT1 receptor | 4ZUD | - | - |
| ECL1 | 109 | G | - | AT1 receptor | 4ZUD | - | - |
| ECL1 | 110 | T | - | AT1 receptor | 4ZUD | - | - |
| ECL1 | 111 | F | - | - | - | - | - |
| TM3 | 112 | A | 3.21x21 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM3 | 113 | D | 3.22x22 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM3 | 114 | Y | 3.23x23 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM3 | 115 | I | 3.24x24 | CCR6 | 6WWZ | MC4 receptor | 7AUE |
| TM3 | 116 | R | 3.25x25 | CCR6 | 6WWZ | - | - |
| TM3 | 117 | S | 3.26x26 | CCR6 | 6WWZ | C5a1 receptor | 6C1Q |
| TM3 | 118 | V | 3.27x27 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM3 | 119 | C | 3.28x28 | CCR6 | 6WWZ | BLT1 receptor | 7K15 |
| TM3 | 120 | R | 3.29x29 | CCR6 | 6WWZ | P2Y1 receptor | 4XNW |
| TM3 | 121 | V | 3.30x30 | CCR6 | 6WWZ | CXCR4 | 3ODU |
| TM3 | 122 | L | 3.31x31 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM3 | 123 | G | 3.32x32 | CCR6 | 6WWZ | Rhodopsin | 6I9K |
| TM3 | 124 | L | 3.33x33 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM3 | 125 | C | 3.34x34 | CCR6 | 6WWZ | PAR1 | 3VW7 |
| TM3 | 126 | M | 3.35x35 | CCR6 | 6WWZ | D3 receptor | 7CMV |
| TM3 | 127 | F | 3.36x36 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 128 | L | 3.37x37 | CCR6 | 6WWZ | MC4 receptor | 7AUE |
| TM3 | 129 | T | 3.38x38 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM3 | 130 | G | 3.39x39 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 131 | V | 3.40x40 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM3 | 132 | S | 3.41x41 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM3 | 133 | L | 3.42x42 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 134 | L | 3.43x43 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 135 | P | 3.44x44 | CCR6 | 6WWZ | - | - |
| TM3 | 136 | A | 3.45x45 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM3 | 137 | V | 3.46x46 | CCR6 | 6WWZ | GPBA receptor | 7CFN |
| TM3 | 138 | S | 3.47x47 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 139 | A | 3.48x48 | CCR6 | 6WWZ | P2Y1 receptor | 4XNW |
| TM3 | 140 | E | 3.49x49 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM3 | 141 | R | 3.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 142 | C | 3.51x51 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| TM3 | 143 | A | 3.52x52 | CCR6 | 6WWZ | - | - |
| TM3 | 144 | S | 3.53x53 | CCR6 | 6WWZ | AT2 receptor | 5UNG |
| TM3 | 145 | V | 3.54x54 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| TM3 | 146 | I | 3.55x55 | CCR6 | 6WWZ | AT2 receptor | 5UNG |
| TM3 | 147 | F | 3.56x56 | AT1 receptor | 4ZUD | CysLT1 receptor | 6RZ4 |
| ICL2 | 148 | P | 34.50x50 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| ICL2 | 149 | A | 34.51x51 | CCR6 | 6WWZ | C5a1 receptor | 5O9H |
| ICL2 | 150 | W | 34.52x52 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| ICL2 | 151 | Y | 34.53x53 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| ICL2 | 152 | W | 34.54x54 | CCR6 | 6WWZ | - | - |
| ICL2 | 153 | R | 34.55x55 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| ICL2 | 154 | R | 34.56x56 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| ICL2 | 155 | R | 34.57x57 | - | - | - | - |
| TM4 | 156 | P | 4.38x38 | AT1 receptor | 6DO1 | US28 | 5WB1 |
| TM4 | 157 | K | 4.39x39 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM4 | 158 | R | 4.40x40 | CCR6 | 6WWZ | μ receptor | 5C1M |
| TM4 | 159 | L | 4.41x41 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| TM4 | 160 | S | 4.42x42 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 161 | A | 4.43x43 | CCR6 | 6WWZ | 5-HT1B receptor | 6G79 |
| TM4 | 162 | V | 4.44x44 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM4 | 163 | V | 4.45x45 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| TM4 | 164 | C | 4.46x46 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 165 | A | 4.47x47 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM4 | 166 | L | 4.48x48 | CCR6 | 6WWZ | AT2 receptor | 5UNG |
| TM4 | 167 | L | 4.49x49 | CCR6 | 6WWZ | DP2 receptor | 6D27 |
| TM4 | 168 | W | 4.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 169 | V | 4.51x51 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM4 | 170 | L | 4.52x52 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 171 | S | 4.53x53 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 172 | L | 4.54x54 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| TM4 | 173 | L | 4.55x55 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM4 | 174 | V | 4.56x56 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM4 | 175 | T | 4.57x57 | P2Y1 receptor | 4XNW | FPR2/ALX | 6OMM |
| TM4 | 176 | C | 4.58x58 | P2Y1 receptor | 4XNW | - | - |
| TM4 | 177 | L | 4.59x59 | P2Y1 receptor | 4XNW | AT1 receptor | 6DO1 |
| TM4 | 178 | H | 4.60x60 | CCR6 | 6WWZ | - | - |
| TM4 | 179 | N | 4.61x61 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM4 | 180 | Y | 4.62x62 | CCR6 | 6WWZ | PAR2 | 5NDD |
| TM4 | 181 | F | 4.63x63 | CCR6 | 6WWZ | M2 receptor | 4MQT |
| TM4 | 182 | C | 4.64x64 | CCR6 | 6WWZ | - | - |
| ECL2 | 183 | V | - | - | - | - | - |
| ECL2 | 184 | F | - | - | - | - | - |
| ECL2 | 185 | L | - | - | - | - | - |
| ECL2 | 186 | G | - | - | - | - | - |
| ECL2 | 187 | R | - | - | - | - | - |
| ECL2 | 188 | G | - | - | - | - | - |
| ECL2 | 189 | A | - | - | - | - | - |
| ECL2 | 190 | P | - | - | - | - | - |
| ECL2 | 191 | G | - | - | - | - | - |
| TM5 | 192 | A | 5.31x32 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| TM5 | 193 | A | 5.32x33 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM5 | 194 | C | 5.33x34 | CCR6 | 6WWZ | - | - |
| TM5 | 195 | R | 5.34x35 | CCR6 | 6WWZ | C5a1 receptor | 6C1Q |
| TM5 | 196 | H | 5.35x36 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM5 | 197 | M | 5.36x37 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM5 | 198 | D | 5.37x38 | CCR6 | 6WWZ | D3 receptor | 7CMV |
| TM5 | 199 | I | 5.38x39 | CCR6 | 6WWZ | AT2 receptor | 5UNG |
| TM5 | 200 | F | 5.39x40 | CCR6 | 6WWZ | GPR52 | 6LI3 |
| TM5 | 201 | L | 5.40x41 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM5 | 202 | G | 5.41x42 | CCR6 | 6WWZ | M2 receptor | 4MQT |
| TM5 | 203 | I | 5.42x43 | CCR6 | 6WWZ | V2 receptor | 7KH0 |
| TM5 | 204 | L | 5.43x44 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 205 | L | 5.44x45 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 206 | F | 5.45x46 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 207 | L | 5.46x461 | CCR6 | 6WWZ | GPR52 | 6LI3 |
| TM5 | 208 | L | 5.47x47 | CCR6 | 6WWZ | GPR52 | 6LI3 |
| TM5 | 209 | C | 5.48x48 | CCR6 | 6WWZ | P2Y1 receptor | 4XNW |
| TM5 | 210 | C | 5.49x49 | CCR6 | 6WWZ | - | - |
| TM5 | 211 | P | 5.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 212 | L | 5.51x51 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 213 | M | 5.52x52 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 214 | V | 5.53x53 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM5 | 215 | L | 5.54x54 | CCR6 | 6WWZ | 5-HT1B receptor | 6G79 |
| TM5 | 216 | P | 5.55x55 | CCR6 | 6WWZ | - | - |
| TM5 | 217 | C | 5.56x56 | CCR6 | 6WWZ | GPR52 | 6LI3 |
| TM5 | 218 | L | 5.57x57 | CCR6 | 6WWZ | 5-HT1B receptor | 6G79 |
| TM5 | 219 | A | 5.58x58 | CCR6 | 6WWZ | - | - |
| TM5 | 220 | L | 5.59x59 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM5 | 221 | I | 5.60x60 | CCR6 | 6WWZ | NTS1 receptor | 6OSA |
| TM5 | 222 | L | 5.61x61 | CCR6 | 6WWZ | Rhodopsin | 4X1H |
| TM5 | 223 | H | 5.62x62 | CCR6 | 6WWZ | - | - |
| TM5 | 224 | V | 5.63x63 | CCR6 | 6WWZ | 5-HT1B receptor | 6G79 |
| TM5 | 225 | E | 5.64x64 | CCR6 | 6WWZ | 5-HT1B receptor | 6G79 |
| TM5 | 226 | C | 5.65x65 | CCR6 | 6WWZ | - | - |
| TM5 | 227 | R | 5.66x66 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM5 | 228 | A | 5.67x67 | CCR6 | 6WWZ | V2 receptor | 7KH0 |
| TM5 | 229 | R | 5.68x68 | CCR6 | 6WWZ | C5a1 receptor | 6C1R |
| ICL3 | 230 | R | - | - | - | - | - |
| ICL3 | 231 | R | - | - | - | - | - |
| ICL3 | 232 | Q | - | - | - | - | - |
| ICL3 | 233 | R | - | - | - | - | - |
| TM6 | 234 | S | 6.30x30 | CCR6 | 6WWZ | C5a1 receptor | 6C1Q |
| TM6 | 235 | A | 6.31x31 | CCR6 | 6WWZ | V2 receptor | 7KH0 |
| TM6 | 236 | K | 6.32x32 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 237 | L | 6.33x33 | CCR6 | 6WWZ | CB2 receptor | 6PT0 |
| TM6 | 238 | N | 6.34x34 | CCR6 | 6WWZ | Y1 receptor | 5ZBH |
| TM6 | 239 | H | 6.35x35 | CCR6 | 6WWZ | - | - |
| TM6 | 240 | V | 6.36x36 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 241 | I | 6.37x37 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 242 | L | 6.38x38 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM6 | 243 | A | 6.39x39 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 244 | M | 6.40x40 | CCR6 | 6WWZ | Rhodopsin | 4X1H |
| TM6 | 245 | V | 6.41x41 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 246 | S | 6.42x42 | CCR6 | 6WWZ | GPR52 | 6LI3 |
| TM6 | 247 | V | 6.43x43 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 248 | F | 6.44x44 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 249 | L | 6.45x45 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 250 | V | 6.46x46 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM6 | 251 | S | 6.47x47 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM6 | 252 | S | 6.48x48 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM6 | 253 | I | 6.49x49 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 254 | Y | 6.50x50 | CCR6 | 6WWZ | - | - |
| TM6 | 255 | L | 6.51x51 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM6 | 256 | G | 6.52x52 | CCR6 | 6WWZ | - | - |
| TM6 | 257 | I | 6.53x53 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM6 | 258 | D | 6.54x54 | CCR6 | 6WWZ | - | - |
| TM6 | 259 | W | 6.55x55 | CCR6 | 6WWZ | - | - |
| TM6 | 260 | F | 6.56x56 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM6 | 261 | L | 6.57x57 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM6 | 262 | F | 6.58x58 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM6 | 263 | W | 6.59x59 | CCR6 | 6WWZ | GnRH1 receptor | 7BR3 |
| TM6 | 264 | V | 6.60x60 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| TM6 | 265 | F | 6.61x61 | AT1 receptor | 4ZUD | OX2 receptor | 7L1V |
| ECL3 | 266 | Q | - | - | - | - | - |
| ECL3 | 267 | I | - | - | - | - | - |
| ECL3 | 268 | P | - | - | - | - | - |
| ECL3 | 269 | A | - | - | - | - | - |
| TM7 | 270 | P | 7.32x31 | CCR6 | 6WWZ | D3 receptor | 7CMV |
| TM7 | 271 | F | 7.33x32 | CCR6 | 6WWZ | S1P1 receptor | 3V2Y |
| TM7 | 272 | P | 7.34x33 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM7 | 273 | E | 7.35x34 | CCR6 | 6WWZ | LPA1 receptor | 4Z35 |
| TM7 | 274 | Y | 7.36x35 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM7 | 275 | V | 7.37x36 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 276 | T | 7.38x37 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 277 | D | 7.39x38 | CCR6 | 6WWZ | - | - |
| TM7 | 278 | L | 7.40x39 | CCR6 | 6WWZ | AT2 receptor | 5UNG |
| TM7 | 279 | C | 7.41x40 | CCR6 | 6WWZ | - | - |
| TM7 | 280 | I | 7.42x41 | CCR6 | 6WWZ | MC4 receptor | 7AUE |
| TM7 | 281 | C | 7.43x42 | CCR6 | 6WWZ | CCR7 | 6QZH |
| TM7 | 282 | I | 7.44x43 | CCR6 | 6WWZ | δ receptor | 6PT2 |
| TM7 | 283 | N | 7.45x45 | CCR6 | 6WWZ | AT1 receptor | 6DO1 |
| TM7 | 284 | S | 7.46x46 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| TM7 | 285 | S | 7.47x47 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM7 | 286 | A | 7.48x48 | CCR6 | 6WWZ | OX2 receptor | 7L1V |
| TM7 | 287 | K | 7.49x49 | CCR6 | 6WWZ | OT receptor | 6TPK |
| TM7 | 288 | P | 7.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 289 | I | 7.51x51 | CCR6 | 6WWZ | 5-HT1B receptor | 6G79 |
| TM7 | 290 | V | 7.52x52 | CCR6 | 6WWZ | A1 receptor | 6D9H |
| TM7 | 291 | Y | 7.53x53 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 292 | F | 7.54x54 | CCR6 | 6WWZ | P2Y1 receptor | 4XNW |
| TM7 | 293 | L | 7.55x55 | CCR6 | 6WWZ | MC4 receptor | 7AUE |
| TM7 | 294 | A | 7.56x56 | CCR6 | 6WWZ | C5a1 receptor | 6C1Q |
| H8 | 295 | G | 8.47x47 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| H8 | 296 | R | 8.48x48 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| H8 | 297 | D | 8.49x49 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| H8 | 298 | K | 8.50x50 | CCR6 | 6WWZ | - | - |
| H8 | 299 | S | 8.51x51 | CCR6 | 6WWZ | V2 receptor | 7KH0 |
| H8 | 300 | Q | 8.52x52 | CCR6 | 6WWZ | US28 | 5WB1 |
| H8 | 301 | R | 8.53x53 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| H8 | 302 | L | 8.54x54 | CCR6 | 6WWZ | FPR2/ALX | 6OMM |
| H8 | 303 | W | 8.55x55 | CCR6 | 6WWZ | - | - |
| H8 | 304 | E | 8.56x56 | CCR6 | 6WWZ | MC4 receptor | 7AUE |
| H8 | 305 | P | 8.57x57 | CCR6 | 6WWZ | - | - |
| H8 | 306 | L | 8.58x58 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| H8 | 307 | R | 8.59x59 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| H8 | 308 | V | 8.60x60 | CCR6 | 6WWZ | - | - |
| H8 | 309 | V | 8.61x61 | CCR6 | 6WWZ | DP2 receptor | 6D27 |
| H8 | 310 | F | 8.62x62 | CCR6 | 6WWZ | succinate receptor | 6IBB |
| C-term | 311 | Q | - | CCR6 | 6WWZ | CCR6 | 6WWZ |
| C-term | 312 | R | - | - | - | - | - |
| C-term | 313 | A | - | - | - | - | - |
| C-term | 314 | L | - | - | - | - | - |
| C-term | 315 | R | - | - | - | - | - |