TAS2R5 homology model

PROTEIN CLASS

Class T (Taste 2)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive

VERSION

2021-11-02

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

H1 receptor (sequence similarity: 18%) PDB: 3RZE

TEMPLATES

7BVQ (β1-adrenoceptor)
3RZE (H1 receptor)
6M9T (EP3 receptor)
5ZKQ (PAF receptor)
5VBL (apelin receptor)
6KO5 (ghrelin receptor)
7EZM (CCK1 receptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 72.8 12.2 15.0
Side-chains 12.2 58.2 29.6

Number of backbone templates: 7
Number of rotamer templates: 56

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 1 M - - - - -
N-term 2 L - - - - -
N-term 3 S - - - - -
N-term 4 A - - - - -
N-term 5 G - - - - -
TM1 6 L 1.32x32 β1-adrenoceptor 7BVQ ghrelin receptor 6KO5
TM1 7 G 1.33x33 β1-adrenoceptor 7BVQ - -
TM1 8 L 1.34x34 β1-adrenoceptor 7BVQ apelin receptor 5VBL
TM1 9 L 1.35x35 β1-adrenoceptor 7BVQ α2A-adrenoceptor 6KUX
TM1 10 M 1.36x36 β1-adrenoceptor 7BVQ μ receptor 4DKL
TM1 11 L 1.37x37 β1-adrenoceptor 7BVQ β1-adrenoceptor 7BVQ
TM1 12 V 1.38x38 H1 receptor 3RZE H1 receptor 3RZE
TM1 13 A 1.39x39 H1 receptor 3RZE α2A-adrenoceptor 6KUX
TM1 14 V 1.40x40 H1 receptor 3RZE 5-HT2C receptor 6BQH
TM1 15 V 1.41x41 H1 receptor 3RZE κ receptor 4DJH
TM1 16 E 1.42x42 H1 receptor 3RZE β3-adrenoceptor 7DH5
TM1 17 F 1.43x43 H1 receptor 3RZE apelin receptor 5VBL
TM1 18 L 1.44x44 H1 receptor 3RZE H1 receptor 3RZE
TM1 19 I 1.45x45 H1 receptor 3RZE Rhodopsin 6I9K
TM1 20 G 1.46x46 H1 receptor 3RZE apelin receptor 5VBL
TM1 21 L 1.47x47 H1 receptor 3RZE κ receptor 4DJH
TM1 22 I 1.48x48 H1 receptor 3RZE ETB receptor 5X93
TM1 23 G 1.49x49 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM1 24 N 1.50x50 H1 receptor 3RZE H1 receptor 3RZE
TM1 25 G 1.51x51 H1 receptor 3RZE apelin receptor 5VBL
TM1 26 S 1.52x52 H1 receptor 3RZE GnRH1 receptor 7BR3
TM1 27 L 1.53x53 H1 receptor 3RZE ETB receptor 5X93
TM1 28 V 1.54x54 H1 receptor 3RZE α2C-adrenoceptor 6KUW
TM1 29 V 1.55x55 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM1 30 W 1.56x56 H1 receptor 3RZE - -
TM1 31 S 1.57x57 H1 receptor 3RZE - -
TM1 32 F 1.58x58 H1 receptor 3RZE apelin receptor 5VBL
TM1 33 R 1.59x59 H1 receptor 3RZE apelin receptor 5VBL
TM1 34 E 1.60x60 H1 receptor 3RZE H1 receptor 3RZE
TM1 35 W 1.61x61 EP3 receptor 6M9T - -
TM1 36 I 1.62x62 EP3 receptor 6M9T - -
ICL1 37 R 12.48x48 H1 receptor 3RZE H1 receptor 3RZE
ICL1 38 K 12.49x49 H1 receptor 3RZE H1 receptor 3RZE
ICL1 39 F 12.50x50 H1 receptor 3RZE LPA1 receptor 4Z35
ICL1 40 N 12.51x51 H1 receptor 3RZE - -
TM2 41 W 2.36x36 PAF receptor 5ZKQ - -
TM2 42 S 2.37x37 H1 receptor 3RZE CXCR2 6LFL
TM2 43 S 2.38x38 H1 receptor 3RZE apelin receptor 5VBL
TM2 44 Y 2.39x39 H1 receptor 3RZE - -
TM2 45 N 2.40x40 H1 receptor 3RZE H1 receptor 3RZE
TM2 46 L 2.41x41 H1 receptor 3RZE H1 receptor 3RZE
TM2 47 I 2.42x42 H1 receptor 3RZE Rhodopsin 1U19
TM2 48 I 2.43x43 H1 receptor 3RZE H1 receptor 3RZE
TM2 49 L 2.44x44 H1 receptor 3RZE Rhodopsin 6I9K
TM2 50 G 2.45x45 H1 receptor 3RZE EP4 receptor 5YWY
TM2 51 L 2.46x46 H1 receptor 3RZE H1 receptor 3RZE
TM2 52 A 2.47x47 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM2 53 G 2.48x48 H1 receptor 3RZE CB2 receptor 6PT0
TM2 54 C 2.49x49 H1 receptor 3RZE S1P3 receptor 7EW4
TM2 55 R 2.50x50 H1 receptor 3RZE - -
TM2 56 F 2.51x51 H1 receptor 3RZE Rhodopsin 6I9K
TM2 57 L 2.52x52 H1 receptor 3RZE α2A-adrenoceptor 6KUX
TM2 58 L 2.53x53 H1 receptor 3RZE 5-HT2A receptor 6A94
TM2 59 Q 2.54x54 H1 receptor 3RZE EP3 receptor 6AK3
TM2 60 W 2.55x55 apelin receptor 5VBL - -
TM2 61 L 2.56x56 apelin receptor 5VBL - -
TM2 62 I 2.57x57 H1 receptor 3RZE α2A-adrenoceptor 6KUX
TM2 63 I 2.58x58 H1 receptor 3RZE - -
TM2 64 L 2.59x59 H1 receptor 3RZE apelin receptor 5VBL
TM2 65 D 2.60x60 H1 receptor 3RZE ghrelin receptor 6KO5
TM2 66 L 2.61x61 H1 receptor 3RZE α2A-adrenoceptor 6KUX
TM2 67 S 2.62x62 H1 receptor 3RZE Rhodopsin 6I9K
TM2 68 L 2.63x63 H1 receptor 3RZE D2 receptor 6LUQ
TM2 69 F 2.64x64 H1 receptor 3RZE CB1 receptor 5TGZ
TM2 70 P 2.65x65 H1 receptor 3RZE - -
TM2 71 L 2.66x66 H1 receptor 3RZE - -
ECL1 72 F - H1 receptor 3RZE - -
ECL1 73 Q - H1 receptor 3RZE H1 receptor 3RZE
ECL1 74 S - H1 receptor 3RZE H1 receptor 3RZE
ECL1 75 S - H1 receptor 3RZE H1 receptor 3RZE
ECL1 76 R - H1 receptor 3RZE H1 receptor 3RZE
TM3 77 W 3.24x24 H1 receptor 3RZE β2-adrenoceptor 4GBR
TM3 78 L 3.25x25 H1 receptor 3RZE - -
TM3 79 R 3.26x26 H1 receptor 3RZE OT receptor 6TPK
TM3 80 Y 3.27x27 H1 receptor 3RZE EP4 receptor 5YWY
TM3 81 L 3.28x28 H1 receptor 3RZE CCR5 4MBS
TM3 82 S 3.29x29 H1 receptor 3RZE apelin receptor 5VBL
TM3 83 I 3.30x30 H1 receptor 3RZE FPR2/ALX 6OMM
TM3 84 F 3.31x31 H1 receptor 3RZE NK1 receptor 6HLP
TM3 85 W 3.32x32 H1 receptor 3RZE - -
TM3 86 V 3.33x33 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM3 87 L 3.34x34 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM3 88 V 3.35x35 H1 receptor 3RZE M2 receptor 5YC8
TM3 89 S 3.36x36 H1 receptor 3RZE H1 receptor 3RZE
TM3 90 Q 3.37x37 H1 receptor 3RZE A2A receptor 5IU4
TM3 91 A 3.38x38 H1 receptor 3RZE H1 receptor 3RZE
TM3 92 S 3.39x39 H1 receptor 3RZE H1 receptor 3RZE
TM3 93 L 3.40x40 H1 receptor 3RZE EP4 receptor 5YWY
TM3 94 W 3.41x41 H1 receptor 3RZE α2A-adrenoceptor 6KUX
TM3 95 F 3.42x42 H1 receptor 3RZE CCR5 4MBS
TM3 96 A 3.43x43 H1 receptor 3RZE EP3 receptor 6AK3
TM3 97 T 3.44x44 H1 receptor 3RZE apelin receptor 5VBL
TM3 98 F 3.45x45 H1 receptor 3RZE CXCR4 3ODU
TM3 99 L 3.46x46 H1 receptor 3RZE H1 receptor 3RZE
TM3 100 S 3.47x47 H1 receptor 3RZE apelin receptor 5VBL
TM3 101 V 3.48x48 H1 receptor 3RZE κ receptor 4DJH
TM3 102 F 3.49x49 H1 receptor 3RZE CysLT1 receptor 6RZ4
TM3 103 Y 3.50x50 H1 receptor 3RZE - -
TM3 104 C 3.51x51 H1 receptor 3RZE DP2 receptor 7M8W
TM3 105 K 3.52x52 H1 receptor 3RZE - -
TM3 106 K 3.53x53 H1 receptor 3RZE P2Y12 receptor 4NTJ
TM3 107 I 3.54x54 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM3 108 T 3.55x55 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM3 109 T 3.56x56 H1 receptor 3RZE - -
ICL2 110 F - - - - -
ICL2 111 D - - - - -
ICL2 112 R 34.50x50 β1-adrenoceptor 7BVQ - -
ICL2 113 P 34.51x51 β1-adrenoceptor 7BVQ CB2 receptor 5ZTY
ICL2 114 A 34.52x52 β1-adrenoceptor 7BVQ MT2 receptor 6ME7
ICL2 115 Y 34.53x53 β1-adrenoceptor 7BVQ β1-adrenoceptor 7BVQ
ICL2 116 L 34.54x54 β1-adrenoceptor 7BVQ κ receptor 6VI4
ICL2 117 W 34.55x55 β1-adrenoceptor 7BVQ - -
ICL2 118 L 34.56x56 β1-adrenoceptor 7BVQ β1-adrenoceptor 7BVQ
ICL2 119 K 34.57x57 - - - -
TM4 120 Q 4.38x38 H1 receptor 3RZE - -
TM4 121 R 4.39x39 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM4 122 A 4.40x40 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM4 123 Y 4.41x41 H1 receptor 3RZE CCR9 5LWE
TM4 124 N 4.42x42 H1 receptor 3RZE - -
TM4 125 L 4.43x43 H1 receptor 3RZE Rhodopsin 6I9K
TM4 126 S 4.44x44 H1 receptor 3RZE GnRH1 receptor 7BR3
TM4 127 L 4.45x45 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM4 128 W 4.46x46 H1 receptor 3RZE - -
TM4 129 C 4.47x47 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM4 130 L 4.48x48 H1 receptor 3RZE 5-HT1B receptor 4IAQ
TM4 131 L 4.49x49 H1 receptor 3RZE apelin receptor 5VBL
TM4 132 G 4.50x50 H1 receptor 3RZE - -
TM4 133 Y 4.51x51 H1 receptor 3RZE - -
TM4 134 F 4.52x52 H1 receptor 3RZE 5-HT1B receptor 4IAQ
TM4 135 I 4.53x53 H1 receptor 3RZE PAF receptor 5ZKQ
TM4 136 I 4.54x54 H1 receptor 3RZE 5-HT1B receptor 4IAQ
TM4 137 N 4.55x55 β1-adrenoceptor 7BVQ - -
TM4 138 L 4.56x56 β1-adrenoceptor 7BVQ apelin receptor 5VBL
TM4 139 L 4.57x57 β1-adrenoceptor 7BVQ MT2 receptor 6ME7
TM4 140 L 4.58x58 H1 receptor 3RZE 5-HT1B receptor 4IAQ
TM4 141 T 4.59x59 H1 receptor 3RZE A2A receptor 5IU4
TM4 142 V 4.60x60 H1 receptor 3RZE μ receptor 4DKL
TM4 143 Q 4.61x61 H1 receptor 3RZE NK1 receptor 6HLP
TM4 144 I 4.62x62 H1 receptor 3RZE CCR5 4MBS
TM4 145 G 4.63x63 H1 receptor 3RZE H1 receptor 3RZE
TM4 146 L 4.64x64 β1-adrenoceptor 7BVQ apelin receptor 5VBL
ECL2 147 T - - - - -
ECL2 148 F - - - - -
ECL2 149 Y - - - - -
ECL2 150 H - - - - -
ECL2 151 P - - - - -
ECL2 152 P - - - - -
ECL2 153 Q - - - - -
ECL2 154 G - - - - -
ECL2 155 N - - - - -
ECL2 156 S - - - - -
ECL2 157 S - - - - -
ECL2 158 I - - - - -
ECL2 159 R - - - - -
ECL2 160 Y - - - - -
ECL2 161 P - - - - -
TM5 162 F 5.32x32 apelin receptor 5VBL - -
TM5 163 E 5.33x33 apelin receptor 5VBL BLT1 receptor 7K15
TM5 164 S 5.34x34 apelin receptor 5VBL Y1 receptor 5ZBH
TM5 165 W 5.35x35 apelin receptor 5VBL apelin receptor 5VBL
TM5 166 Q 5.36x36 H1 receptor 3RZE M1 receptor 6WJC
TM5 167 Y 5.37x37 H1 receptor 3RZE PAR1 3VW7
TM5 168 L 5.38x38 H1 receptor 3RZE 5-HT1B receptor 4IAQ
TM5 169 Y 5.39x39 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM5 170 A 5.40x40 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM5 171 F 5.41x41 H1 receptor 3RZE CXCR4 3ODU
TM5 172 Q 5.42x42 H1 receptor 3RZE CXCR4 3ODU
TM5 173 L 5.43x43 H1 receptor 3RZE ETB receptor 5X93
TM5 174 N 5.44x44 H1 receptor 3RZE CCR2 5T1A
TM5 175 S 5.45x45 H1 receptor 3RZE CXCR2 6LFL
TM5 176 G 5.46x46 ghrelin receptor 6KO5 α2A-adrenoceptor 6KUX
TM5 177 S 5.47x47 ghrelin receptor 6KO5 EP4 receptor 5YWY
TM5 178 Y 5.48x48 H1 receptor 3RZE H1 receptor 3RZE
TM5 179 L 5.49x49 H1 receptor 3RZE H1 receptor 3RZE
TM5 180 P 5.50x50 H1 receptor 3RZE H1 receptor 3RZE
TM5 181 L 5.51x51 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM5 182 V 5.52x52 H1 receptor 3RZE β2-adrenoceptor 4GBR
TM5 183 V 5.53x53 H1 receptor 3RZE MT2 receptor 6ME7
TM5 184 F 5.54x54 H1 receptor 3RZE - -
TM5 185 L 5.55x55 H1 receptor 3RZE H1 receptor 3RZE
TM5 186 V 5.56x56 H1 receptor 3RZE κ receptor 4DJH
TM5 187 S 5.57x57 H1 receptor 3RZE DP2 receptor 7M8W
TM5 188 S 5.58x58 H1 receptor 3RZE LPA6 receptor 5XSZ
TM5 189 G 5.59x59 H1 receptor 3RZE 5-HT1B receptor 4IAQ
TM5 190 M 5.60x60 H1 receptor 3RZE LPA6 receptor 5XSZ
TM5 191 L 5.61x61 H1 receptor 3RZE Rhodopsin 1GZM
TM5 192 I 5.62x62 H1 receptor 3RZE κ receptor 4DJH
TM5 193 V 5.63x63 H1 receptor 3RZE 5-HT1B receptor 4IAQ
TM5 194 S 5.64x64 H1 receptor 3RZE 5-HT2A receptor 6A94
TM5 195 L 5.65x65 H1 receptor 3RZE κ receptor 4DJH
TM5 196 Y 5.66x66 CCK1 receptor 7EZM CCK1 receptor 7EZM
TM5 197 T 5.67x67 CCK1 receptor 7EZM S1P1 receptor 3V2Y
TM5 198 H 5.68x68 CCK1 receptor 7EZM Rhodopsin 6I9K
TM5 199 H 5.69x69 CCK1 receptor 7EZM EP4 receptor 5YWY
TM5 200 K 5.70x70 CCK1 receptor 7EZM CCK1 receptor 7EZM
TM5 201 K 5.71x71 CCK1 receptor 7EZM β2-adrenoceptor 3SN6
TM5 202 M 5.72x72 CCK1 receptor 7EZM A2A receptor 3VG9
ICL3 203 K - - - - -
ICL3 204 V - - - - -
ICL3 205 H - - - - -
ICL3 206 S - - - - -
ICL3 207 A - - - - -
ICL3 208 G - - - - -
ICL3 209 R - - - - -
ICL3 210 R - - - - -
ICL3 211 D - - - - -
TM6 212 V 6.29x29 H1 receptor 3RZE - -
TM6 213 R 6.30x30 H1 receptor 3RZE ETB receptor 5X93
TM6 214 A 6.31x31 H1 receptor 3RZE V2 receptor 7KH0
TM6 215 K 6.32x32 H1 receptor 3RZE H1 receptor 3RZE
TM6 216 A 6.33x33 H1 receptor 3RZE H1 receptor 3RZE
TM6 217 H 6.34x34 H1 receptor 3RZE - -
TM6 218 I 6.35x35 H1 receptor 3RZE Y1 receptor 5ZBH
TM6 219 T 6.36x36 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM6 220 A 6.37x37 H1 receptor 3RZE Rhodopsin 6I9K
TM6 221 L 6.38x38 H1 receptor 3RZE κ receptor 4DJH
TM6 222 K 6.39x39 H1 receptor 3RZE - -
TM6 223 S 6.40x40 H1 receptor 3RZE - -
TM6 224 L 6.41x41 H1 receptor 3RZE 5-HT1B receptor 4IAQ
TM6 225 G 6.42x42 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM6 226 C 6.43x43 H1 receptor 3RZE Rhodopsin 6I9K
TM6 227 F 6.44x44 H1 receptor 3RZE H1 receptor 3RZE
TM6 228 L 6.45x45 H1 receptor 3RZE 5-HT2C receptor 6BQH
TM6 229 L 6.46x46 H1 receptor 3RZE H1 receptor 3RZE
TM6 230 L 6.47x47 H1 receptor 3RZE succinate receptor 6RNK
TM6 231 H 6.48x48 H1 receptor 3RZE - -
TM6 232 L 6.49x49 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM6 233 V 6.50x50 H1 receptor 3RZE - -
TM6 234 Y 6.51x51 H1 receptor 3RZE H1 receptor 3RZE
TM6 235 I 6.52x52 H1 receptor 3RZE GPR52 6LI1
TM6 236 M 6.53x53 H1 receptor 3RZE CCR6 6WWZ
TM6 237 A 6.54x54 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM6 238 S 6.55x55 H1 receptor 3RZE 5-HT1B receptor 4IAQ
TM6 239 P 6.56x56 H1 receptor 3RZE - -
TM6 240 F 6.57x57 H1 receptor 3RZE A2A receptor 5IU4
TM6 241 S 6.58x58 H1 receptor 3RZE 5-HT2C receptor 6BQH
TM6 242 I 6.59x59 H1 receptor 3RZE Rhodopsin 6I9K
TM6 243 T 6.60x60 H1 receptor 3RZE ETB receptor 5X93
TM6 244 S 6.61x61 H1 receptor 3RZE ghrelin receptor 6KO5
ECL3 245 K - - - - -
ECL3 246 T - - - - -
ECL3 247 Y - - - - -
ECL3 248 P - - - - -
ECL3 249 P - - - - -
TM7 250 D 7.31x31 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM7 251 L 7.32x32 H1 receptor 3RZE Y1 receptor 5ZBH
TM7 252 T 7.33x33 H1 receptor 3RZE Rhodopsin 6I9K
TM7 253 S 7.34x34 H1 receptor 3RZE Rhodopsin 6I9K
TM7 254 V 7.35x35 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM7 255 F 7.36x36 H1 receptor 3RZE H1 receptor 3RZE
TM7 256 I 7.37x37 H1 receptor 3RZE NK1 receptor 6HLP
TM7 257 W 7.38x38 H1 receptor 3RZE - -
TM7 258 E 7.39x39 H1 receptor 3RZE - -
TM7 259 T 7.40x40 H1 receptor 3RZE Y1 receptor 5ZBH
TM7 260 L 7.41x41 H1 receptor 3RZE PAF receptor 5ZKQ
TM7 261 M 7.42x42 H1 receptor 3RZE NK1 receptor 6HLP
TM7 262 A 7.43x43 H1 receptor 3RZE β1-adrenoceptor 7BVQ
TM7 263 A 7.44x44 - - - -
TM7 264 Y 7.45x45 H1 receptor 3RZE - -
TM7 265 P 7.46x46 H1 receptor 3RZE EP4 receptor 5YWY
TM7 266 S 7.47x47 H1 receptor 3RZE α2A-adrenoceptor 6KUX
TM7 267 L 7.48x48 H1 receptor 3RZE H1 receptor 3RZE
TM7 268 H 7.49x49 H1 receptor 3RZE - -
TM7 269 S 7.50x50 H1 receptor 3RZE - -
TM7 270 L 7.51x51 H1 receptor 3RZE H1 receptor 3RZE
TM7 271 I 7.52x52 H1 receptor 3RZE H1 receptor 3RZE
TM7 272 L 7.53x53 H1 receptor 3RZE ETB receptor 5X93
TM7 273 I 7.54x54 H1 receptor 3RZE EP4 receptor 5YWY
TM7 274 M 7.55x55 H1 receptor 3RZE 5-HT1B receptor 4IAQ
ICL4 275 G - - - - -
H8 276 I 8.47x47 H1 receptor 3RZE A2A receptor 5IU4
H8 277 P 8.48x48 H1 receptor 3RZE β1-adrenoceptor 7BVQ
H8 278 R 8.49x49 H1 receptor 3RZE apelin receptor 5VBL
H8 279 V 8.50x50 H1 receptor 3RZE EP4 receptor 5YWY
H8 280 K 8.51x51 H1 receptor 3RZE H1 receptor 3RZE
H8 281 Q 8.52x52 H1 receptor 3RZE apelin receptor 5VBL
H8 282 T 8.53x53 H1 receptor 3RZE H1 receptor 3RZE
H8 283 C 8.54x54 H1 receptor 3RZE apelin receptor 5VBL
H8 284 Q 8.55x55 H1 receptor 3RZE β1-adrenoceptor 7BVQ
H8 285 K 8.56x56 H1 receptor 3RZE 5-HT1B receptor 4IAQ
H8 286 I 8.57x57 H1 receptor 3RZE H1 receptor 3RZE
H8 287 L 8.58x58 H1 receptor 3RZE H1 receptor 3RZE
H8 288 W 8.59x59 H1 receptor 3RZE - -
H8 289 K 8.60x60 apelin receptor 5VBL CCR5 7O7F
C-term 290 T - - - - -
C-term 291 V - - - - -
C-term 292 C - - - - -
C-term 293 A - - - - -
C-term 294 R - - - - -