ADGRB1 homology model
PROTEIN CLASS
Class B2 (Adhesion)
RECEPTOR
SPECIES
Homo sapiens
STATE
Inactive
VERSION
2022-06-19
MODEL
MAIN TEMPLATE
TEMPLATES
7WU2 (ADGRD1)
4K5Y (CRF1 receptor)
6PB0 (CRF1 receptor)
7WU3 (ADGRF1)
7WUJ (ADGRG4)
7SF7 (ADGRL3)
7D77 (ADGRG3)
None
4K5Y (CRF1 receptor)
6PB0 (CRF1 receptor)
7WU3 (ADGRF1)
7WUJ (ADGRG4)
7SF7 (ADGRL3)
7D77 (ADGRG3)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 69.8 | 18.5 | 11.6 |
| Side-chains | 17.1 | 44.0 | 38.9 |
Number of backbone templates: 7
Number of rotamer templates: 17
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 935 | L | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| N-term | 936 | S | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| N-term | 937 | A | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| N-term | 938 | D | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| N-term | 939 | A | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| TM1 | 940 | N | 1.32x32 | ADGRD1 | 7WU2 | - | - |
| TM1 | 941 | M | 1.33x33 | ADGRD1 | 7WU2 | - | - |
| TM1 | 942 | E | 1.34x34 | ADGRD1 | 7WU2 | GLP-1 receptor | 7DUQ |
| TM1 | 943 | K | 1.35x35 | ADGRD1 | 7WU2 | - | - |
| TM1 | 944 | A | 1.36x36 | ADGRD1 | 7WU2 | CT receptor | 6NIY |
| TM1 | 945 | T | 1.37x37 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 946 | L | 1.38x38 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM1 | 947 | P | 1.39x39 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 948 | S | 1.40x40 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM1 | 949 | V | 1.41x41 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM1 | 950 | T | 1.42x42 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 951 | L | 1.43x43 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 952 | I | 1.44x44 | CRF1 receptor | 4K5Y | CT receptor | 6NIY |
| TM1 | 953 | V | 1.45x45 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM1 | 954 | G | 1.46x46 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM1 | 955 | C | 1.47x47 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM1 | 956 | G | 1.48x48 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM1 | 957 | V | 1.49x49 | CRF1 receptor | 4K5Y | CRF2 receptor | 6PB1 |
| TM1 | 958 | S | 1.50x50 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM1 | 959 | S | 1.51x51 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM1 | 960 | L | 1.52x52 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM1 | 961 | T | 1.53x53 | CRF1 receptor | 4K5Y | CT receptor | 6NIY |
| TM1 | 962 | L | 1.54x54 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM1 | 963 | L | 1.55x55 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM1 | 964 | M | 1.56x56 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 965 | L | 1.57x57 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 966 | V | 1.58x58 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM1 | 967 | I | 1.59x59 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM1 | 968 | I | 1.60x60 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM1 | 969 | Y | 1.61x61 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM1 | 970 | V | 1.62x62 | CRF1 receptor | 4K5Y | CT receptor | 6NIY |
| TM1 | 971 | S | 1.63x63 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 972 | V | 1.64x64 | CRF1 receptor | 4K5Y | - | - |
| ICL1 | 973 | W | - | - | - | - | - |
| ICL1 | 974 | R | 12.48x48 | ADGRF1 | 7WU3 | CRF1 receptor | 6P9X |
| ICL1 | 975 | Y | 12.49x49 | ADGRF1 | 7WU3 | - | - |
| ICL1 | 976 | I | 12.50x50 | ADGRF1 | 7WU3 | ADGRF1 | 7WU3 |
| ICL1 | 977 | R | 12.51x51 | - | - | - | - |
| TM2 | 978 | S | 2.44x44 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 979 | E | 2.45x45 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 980 | R | 2.46x46 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM2 | 981 | S | 2.47x47 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 982 | V | 2.48x48 | CRF1 receptor | 4K5Y | CRF2 receptor | 6PB1 |
| TM2 | 983 | I | 2.49x49 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM2 | 984 | L | 2.50x50 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM2 | 985 | I | 2.51x51 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM2 | 986 | N | 2.52x52 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM2 | 987 | F | 2.53x53 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 988 | C | 2.54x54 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM2 | 989 | L | 2.55x55 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM2 | 990 | S | 2.56x56 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM2 | 991 | I | 2.57x57 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 992 | I | 2.58x58 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM2 | 993 | S | 2.59x59 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 994 | S | 2.60x60 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 995 | N | 2.61x61 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM2 | 996 | A | 2.62x62 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM2 | 997 | L | 2.63x63 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM2 | 998 | I | 2.64x64 | CRF1 receptor | 4K5Y | CT receptor | 6NIY |
| TM2 | 999 | L | 2.65x65 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM2 | 1000 | I | 2.66x66 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM2 | 1001 | G | 2.67x67 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| ECL1 | 1002 | Q | - | - | - | - | - |
| ECL1 | 1003 | T | - | - | - | - | - |
| ECL1 | 1004 | Q | - | - | - | - | - |
| ECL1 | 1005 | T | - | - | - | - | - |
| ECL1 | 1006 | R | - | - | - | - | - |
| ECL1 | 1007 | N | - | - | - | - | - |
| ECL1 | 1008 | K | - | - | - | - | - |
| TM3 | 1009 | V | 3.27x27 | CRF1 receptor | 4K5Y | CRF2 receptor | 6PB1 |
| TM3 | 1010 | V | 3.28x28 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM3 | 1011 | C | 3.29x29 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 1012 | T | 3.30x30 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM3 | 1013 | L | 3.31x31 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 1014 | V | 3.32x32 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 1015 | A | 3.33x33 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM3 | 1016 | A | 3.34x34 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 1017 | F | 3.35x35 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM3 | 1018 | L | 3.36x36 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM3 | 1019 | H | 3.37x37 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM3 | 1020 | F | 3.38x38 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM3 | 1021 | F | 3.39x39 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 1022 | F | 3.40x40 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM3 | 1023 | L | 3.41x41 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM3 | 1024 | S | 3.42x42 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 1025 | S | 3.43x43 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM3 | 1026 | F | 3.44x44 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 1027 | C | 3.45x45 | CRF1 receptor | 4K5Y | glucagon receptor | 6WPW |
| TM3 | 1028 | W | 3.46x46 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 1029 | V | 3.47x47 | CRF1 receptor | 4K5Y | - | - |
| TM3 | 1030 | L | 3.48x48 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 1031 | T | 3.49x49 | CRF1 receptor | 4K5Y | - | - |
| TM3 | 1032 | E | 3.50x50 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 1033 | A | 3.51x51 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM3 | 1034 | W | 3.52x52 | CRF1 receptor | 4K5Y | - | - |
| TM3 | 1035 | Q | 3.53x53 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM3 | 1036 | S | 3.54x54 | CRF1 receptor | 4K5Y | - | - |
| TM3 | 1037 | Y | 3.55x55 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM3 | 1038 | M | 3.56x56 | CRF1 receptor | 4K5Y | - | - |
| TM3 | 1039 | A | 3.57x57 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 1040 | V | 3.58x58 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 1041 | T | 3.59x59 | CRF1 receptor | 4K5Y | - | - |
| TM3 | 1042 | G | 3.60x60 | CRF1 receptor | 4K5Y | - | - |
| ICL2 | 1043 | H | - | - | - | - | - |
| ICL2 | 1044 | L | - | - | - | - | - |
| ICL2 | 1045 | R | - | - | - | - | - |
| ICL2 | 1046 | N | - | - | - | - | - |
| ICL2 | 1047 | R | - | - | - | - | - |
| ICL2 | 1048 | L | - | - | - | - | - |
| TM4 | 1049 | I | 4.41x42 | CRF1 receptor | 4K5Y | - | - |
| TM4 | 1050 | R | 4.42x43 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM4 | 1051 | K | 4.43x44 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM4 | 1052 | R | 4.44x45 | CRF1 receptor | 4K5Y | GLP-2 receptor | 7D68 |
| TM4 | 1053 | F | 4.45x46 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM4 | 1054 | L | 4.46x47 | CRF1 receptor | 4K5Y | CRF2 receptor | 6PB1 |
| TM4 | 1055 | C | 4.47x48 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM4 | 1056 | L | 4.48x49 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM4 | 1057 | G | 4.49x491 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM4 | 1058 | W | 4.50x50 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM4 | 1059 | G | 4.51x51 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM4 | 1060 | L | 4.52x52 | CRF1 receptor | 4K5Y | ADGRG3 | 7D77 |
| TM4 | 1061 | P | 4.53x53 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM4 | 1062 | A | 4.54x54 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM4 | 1063 | L | 4.55x55 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM4 | 1064 | V | 4.56x56 | CRF1 receptor | 4K5Y | - | - |
| TM4 | 1065 | V | 4.57x57 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM4 | 1066 | A | 4.58x58 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM4 | 1067 | I | 4.59x59 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM4 | 1068 | S | 4.60x60 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM4 | 1069 | V | 4.61x61 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM4 | 1070 | G | 4.62x62 | CRF1 receptor | 4K5Y | - | - |
| TM4 | 1071 | F | 4.63x63 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM4 | 1072 | T | 4.64x64 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| ECL2 | 1073 | K | - | - | - | - | - |
| ECL2 | 1074 | A | - | ADGRF1 | 7WU3 | - | - |
| ECL2 | 1075 | K | - | ADGRF1 | 7WU3 | - | - |
| ECL2 | 1076 | G | - | ADGRF1 | 7WU3 | - | - |
| ECL2 | 1077 | Y | - | ADGRF1 | 7WU3 | ADGRF1 | 7WU3 |
| ECL2 | 1078 | S | - | ADGRF1 | 7WU3 | - | - |
| ECL2 | 1079 | T | - | ADGRF1 | 7WU3 | - | - |
| ECL2 | 1080 | M | - | ADGRF1 | 7WU3 | - | - |
| ECL2 | 1081 | N | - | ADGRF1 | 7WU3 | - | - |
| ECL2 | 1082 | Y | - | - | - | - | - |
| ECL2 | 1083 | C | 45.50x50 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| ECL2 | 1084 | W | 45.51x51 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| ECL2 | 1085 | L | 45.52x52 | CRF1 receptor | 4K5Y | CT receptor | 6NIY |
| ECL2 | 1086 | S | - | - | - | - | - |
| ECL2 | 1087 | L | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| ECL2 | 1088 | E | - | ADGRD1 | 7WU2 | - | - |
| ECL2 | 1089 | G | - | - | - | - | - |
| TM5 | 1090 | G | 5.34x34 | ADGRG4 | 7WUJ | ADGRD1 | 7WU2 |
| TM5 | 1091 | L | 5.35x35 | ADGRG4 | 7WUJ | - | - |
| TM5 | 1092 | L | 5.36x36 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM5 | 1093 | Y | 5.37x37 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM5 | 1094 | A | 5.38x38 | ADGRL3 | 7SF7 | ADGRD1 | 7WU2 |
| TM5 | 1095 | F | 5.39x39 | ADGRL3 | 7SF7 | ADGRL3 | 7SF7 |
| TM5 | 1096 | V | 5.40x40 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM5 | 1097 | G | 5.41x41 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 1098 | P | 5.42x42 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 1099 | A | 5.43x43 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM5 | 1100 | A | 5.44x44 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 1101 | A | 5.45x45 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM5 | 1102 | V | 5.46x46 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 1103 | V | 5.47x47 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM5 | 1104 | L | 5.48x48 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 1105 | V | 5.49x49 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM5 | 1106 | N | 5.50x50 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 1107 | M | 5.51x51 | CRF1 receptor | 4K5Y | ADGRG3 | 7D77 |
| TM5 | 1108 | V | 5.52x52 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM5 | 1109 | I | 5.53x53 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM5 | 1110 | G | 5.54x54 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 1111 | I | 5.55x55 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM5 | 1112 | L | 5.56x56 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM5 | 1113 | V | 5.57x57 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM5 | 1114 | F | 5.58x58 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 1115 | N | 5.59x59 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 1116 | K | 5.60x60 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM5 | 1117 | L | 5.61x61 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 1118 | V | 5.62x62 | CRF1 receptor | 4K5Y | CT receptor | 6NIY |
| TM5 | 1119 | S | 5.63x63 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM5 | 1120 | K | 5.64x64 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 1121 | D | 5.65x65 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 1122 | G | 5.66x66 | ADGRL3 | 7SF7 | - | - |
| TM5 | 1123 | I | 5.67x67 | ADGRL3 | 7SF7 | ADGRL3 | 7SF7 |
| TM5 | 1124 | T | 5.68x68 | ADGRL3 | 7SF7 | CT receptor | 7TYF |
| ICL3 | 1125 | D | - | - | - | - | - |
| ICL3 | 1126 | K | - | ADGRG3 | 7D77 | - | - |
| ICL3 | 1127 | K | - | ADGRG3 | 7D77 | ADGRG3 | 7D77 |
| ICL3 | 1128 | L | - | ADGRG3 | 7D77 | - | - |
| ICL3 | 1129 | K | - | ADGRG3 | 7D77 | - | - |
| ICL3 | 1130 | E | - | - | - | - | - |
| TM6 | 1131 | R | 6.34x34 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 1132 | A | 6.35x35 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 1133 | G | 6.36x36 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 1134 | A | 6.37x37 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 1135 | S | 6.38x38 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 1136 | L | 6.39x39 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM6 | 1137 | W | 6.40x40 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 1138 | S | 6.41x41 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM6 | 1139 | S | 6.42x42 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 1140 | C | 6.43x43 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 1141 | V | 6.44x44 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM6 | 1142 | V | 6.45x45 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 1143 | L | 6.46x46 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM6 | 1144 | P | 6.47x47 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM6 | 1145 | L | 6.48x48 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM6 | 1146 | L | 6.49x49 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM6 | 1147 | A | 6.50x50 | CRF1 receptor | 4K5Y | GLP-1 receptor | 5NX2 |
| TM6 | 1148 | L | 6.51x51 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM6 | 1149 | T | 6.52x52 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM6 | 1150 | W | 6.53x53 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM6 | 1151 | M | 6.54x54 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM6 | 1152 | S | 6.55x55 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 1153 | A | 6.56x56 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM6 | 1154 | V | 6.57x57 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM6 | 1155 | L | 6.58x58 | CRF1 receptor | 4K5Y | - | - |
| ECL3 | 1156 | A | - | - | - | - | - |
| ECL3 | 1157 | V | - | - | - | - | - |
| ECL3 | 1158 | T | - | - | - | - | - |
| ECL3 | 1159 | D | - | - | - | - | - |
| ECL3 | 1160 | R | - | - | - | - | - |
| ECL3 | 1161 | R | - | - | - | - | - |
| TM7 | 1162 | S | 7.35x34 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 1163 | A | 7.36x35 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 1164 | L | 7.37x36 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 1165 | F | 7.38x37 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 1166 | Q | 7.39x38 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM7 | 1167 | I | 7.40x39 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 1168 | L | 7.41x40 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM7 | 1169 | F | 7.42x41 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM7 | 1170 | A | 7.43x42 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM7 | 1171 | V | 7.44x43 | CRF1 receptor | 4K5Y | VPAC1 receptor | 6VN7 |
| TM7 | 1172 | F | 7.45x44 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM7 | 1173 | D | 7.46x45 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 1174 | S | 7.47x46 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 1175 | L | 7.48x47 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM7 | 1176 | E | 7.49x49 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 1177 | G | 7.50x50 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 1178 | F | 7.51x51 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 1179 | V | 7.52x52 | CRF1 receptor | 4K5Y | secretin receptor | 6WZG |
| TM7 | 1180 | I | 7.53x53 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM7 | 1181 | V | 7.54x54 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 1182 | M | 7.55x55 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 1183 | V | 7.56x56 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 1184 | H | 7.57x57 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM7 | 1185 | C | 7.58x58 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 1186 | I | 7.59x59 | CRF1 receptor | 4K5Y | ADGRG3 | 7D77 |
| TM7 | 1187 | L | 7.60x60 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| H8 | 1188 | R | 8.47x47 | ADGRL3 | 7SF7 | - | - |
| H8 | 1189 | R | 8.48x48 | ADGRL3 | 7SF7 | - | - |
| H8 | 1190 | E | 8.49x49 | ADGRL3 | 7SF7 | ADGRL3 | 7SF7 |
| H8 | 1191 | V | 8.50x50 | ADGRL3 | 7SF7 | ADGRL3 | 7SF7 |
| H8 | 1192 | Q | 8.51x51 | ADGRL3 | 7SF7 | ADGRL3 | 7SF7 |
| H8 | 1193 | D | 8.52x52 | ADGRL3 | 7SF7 | - | - |
| H8 | 1194 | A | 8.53x53 | ADGRL3 | 7SF7 | ADGRD1 | 7WU2 |
| H8 | 1195 | V | 8.54x54 | ADGRL3 | 7SF7 | CRF2 receptor | 6PB1 |
| H8 | 1196 | K | 8.55x55 | ADGRL3 | 7SF7 | ADGRD1 | 7WU2 |
| H8 | 1197 | C | 8.56x56 | ADGRL3 | 7SF7 | - | - |
| H8 | 1198 | R | 8.57x57 | ADGRL3 | 7SF7 | CRF1 receptor | 6PB0 |
| H8 | 1199 | V | 8.58x58 | ADGRL3 | 7SF7 | - | - |
| H8 | 1200 | V | 8.59x59 | CRF1 receptor | 6PB0 | GLP-2 receptor | 7D68 |
| H8 | 1201 | D | 8.60x60 | CRF1 receptor | 6PB0 | - | - |
| H8 | 1202 | R | 8.61x61 | CRF1 receptor | 6PB0 | - | - |
| H8 | 1203 | Q | 8.62x62 | CRF1 receptor | 6PB0 | CRF1 receptor | 6PB0 |
| H8 | 1204 | E | 8.63x63 | CRF1 receptor | 6PB0 | - | - |
| C-term | 1205 | E | - | - | - | - | - |
| C-term | 1206 | G | - | - | - | - | - |
| C-term | 1207 | N | - | - | - | - | - |
| C-term | 1208 | G | - | - | - | - | - |
| C-term | 1209 | D | - | - | - | - | - |