SST1 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SST1 receptor

SPECIES

Homo sapiens

STATE

Active

VERSION

2021-10-06

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

κ receptor (sequence similarity: 50%) PDB: 6B73
Align

TEMPLATES

6B73 (κ receptor)
4DJH (κ receptor)
4ZUD (AT1 receptor)
5XSZ (LPA6 receptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 82.0 10.2 7.8
Side-chains 35.4 50.3 14.3

Number of backbone templates: 4
Number of rotamer templates: 47

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 51 L - - - - -
N-term 52 S - - - - -
N-term 53 E - κ receptor 6B73 κ receptor 6B73
N-term 54 G - κ receptor 6B73 κ receptor 6B73
N-term 55 Q - κ receptor 6B73 κ receptor 6B73
TM1 56 G 1.30x30 κ receptor 6B73 NOP receptor 5DHH
TM1 57 S 1.31x31 κ receptor 6B73 5-HT1F receptor 7EXD
TM1 58 A 1.32x32 κ receptor 6B73 μ receptor 5C1M
TM1 59 I 1.33x33 κ receptor 6B73 μ receptor 5C1M
TM1 60 L 1.34x34 κ receptor 6B73 CCR5 7O7F
TM1 61 I 1.35x35 κ receptor 6B73 κ receptor 6B73
TM1 62 S 1.36x36 κ receptor 6B73 5-HT1F receptor 7EXD
TM1 63 F 1.37x37 κ receptor 6B73 US28 5WB1
TM1 64 I 1.38x38 κ receptor 6B73 CXCR2 6LFO
TM1 65 Y 1.39x39 κ receptor 6B73 κ receptor 6B73
TM1 66 S 1.40x40 κ receptor 6B73 κ receptor 6B73
TM1 67 V 1.41x41 κ receptor 6B73 κ receptor 6B73
TM1 68 V 1.42x42 κ receptor 6B73 κ receptor 6B73
TM1 69 C 1.43x43 κ receptor 6B73 μ receptor 5C1M
TM1 70 L 1.44x44 κ receptor 6B73 CCK1 receptor 7EZM
TM1 71 V 1.45x45 κ receptor 6B73 κ receptor 6B73
TM1 72 G 1.46x46 κ receptor 6B73 κ receptor 6B73
TM1 73 L 1.47x47 κ receptor 6B73 κ receptor 6B73
TM1 74 C 1.48x48 κ receptor 6B73 - -
TM1 75 G 1.49x49 κ receptor 6B73 κ receptor 6B73
TM1 76 N 1.50x50 κ receptor 6B73 κ receptor 6B73
TM1 77 S 1.51x51 κ receptor 6B73 κ receptor 6B73
TM1 78 M 1.52x52 κ receptor 6B73 S1P3 receptor 7C4S
TM1 79 V 1.53x53 κ receptor 6B73 κ receptor 6B73
TM1 80 I 1.54x54 κ receptor 6B73 CCK1 receptor 7EZM
TM1 81 Y 1.55x55 κ receptor 6B73 μ receptor 5C1M
TM1 82 V 1.56x56 κ receptor 6B73 κ receptor 6B73
TM1 83 I 1.57x57 κ receptor 6B73 κ receptor 6B73
TM1 84 L 1.58x58 κ receptor 6B73 CXCR2 6LFO
TM1 85 R 1.59x59 κ receptor 6B73 μ receptor 5C1M
TM1 86 Y 1.60x60 κ receptor 6B73 κ receptor 6B73
ICL1 87 A 12.48x48 - - - -
ICL1 88 K 12.49x49 κ receptor 4DJH 5-HT1F receptor 7EXD
ICL1 89 M 12.50x50 κ receptor 4DJH κ receptor 4DJH
ICL1 90 K 12.51x51 - - - -
TM2 91 T 2.37x37 κ receptor 6B73 κ receptor 6B73
TM2 92 A 2.38x38 κ receptor 6B73 κ receptor 6B73
TM2 93 T 2.39x39 κ receptor 6B73 κ receptor 6B73
TM2 94 N 2.40x40 κ receptor 6B73 κ receptor 6B73
TM2 95 I 2.41x41 κ receptor 6B73 κ receptor 6B73
TM2 96 Y 2.42x42 κ receptor 6B73 κ receptor 6B73
TM2 97 I 2.43x43 κ receptor 6B73 κ receptor 6B73
TM2 98 L 2.44x44 κ receptor 6B73 AT1 receptor 6DO1
TM2 99 N 2.45x45 κ receptor 6B73 κ receptor 6B73
TM2 100 L 2.46x46 κ receptor 6B73 κ receptor 6B73
TM2 101 A 2.47x47 κ receptor 6B73 κ receptor 6B73
TM2 102 I 2.48x48 κ receptor 6B73 CCR5 7O7F
TM2 103 A 2.49x49 κ receptor 6B73 κ receptor 6B73
TM2 104 D 2.50x50 κ receptor 6B73 κ receptor 6B73
TM2 105 E 2.51x51 κ receptor 6B73 - -
TM2 106 L 2.52x52 κ receptor 6B73 κ receptor 6B73
TM2 107 L 2.53x53 κ receptor 6B73 CCK1 receptor 7EZM
TM2 108 M 2.54x54 κ receptor 6B73 - -
TM2 109 L 2.55x55 κ receptor 6B73 AT1 receptor 6DO1
TM2 110 S 2.56x56 κ receptor 6B73 M2 receptor 4MQT
TM2 111 V 2.57x57 κ receptor 6B73 CCR5 7O7F
TM2 112 P 2.58x58 κ receptor 6B73 κ receptor 6B73
TM2 113 F 2.59x59 κ receptor 6B73 κ receptor 6B73
TM2 114 L 2.60x60 κ receptor 6B73 FPR2/ALX 6OMM
TM2 115 V 2.61x61 κ receptor 6B73 D2 receptor 7JVR
TM2 116 T 2.62x62 κ receptor 6B73 κ receptor 6B73
TM2 117 S 2.63x63 κ receptor 6B73 CXCR2 6LFO
TM2 118 T 2.64x64 κ receptor 6B73 AT1 receptor 6DO1
TM2 119 L 2.65x65 κ receptor 6B73 κ receptor 6B73
TM2 120 L 2.66x66 κ receptor 6B73 CCK1 receptor 7EZM
ECL1 121 R - - - - -
ECL1 122 H 23.49x49 κ receptor 4DJH M1 receptor 6OIJ
ECL1 123 W 23.50x50 κ receptor 4DJH κ receptor 4DJH
ECL1 124 P 23.51x51 κ receptor 4DJH κ receptor 4DJH
ECL1 125 F 23.52x52 - - - -
TM3 126 G 3.21x21 κ receptor 6B73 κ receptor 6B73
TM3 127 A 3.22x22 κ receptor 6B73 β3-adrenoceptor 7DH5
TM3 128 L 3.23x23 κ receptor 6B73 δ receptor 6PT2
TM3 129 L 3.24x24 κ receptor 6B73 κ receptor 6B73
TM3 130 C 3.25x25 κ receptor 6B73 κ receptor 6B73
TM3 131 R 3.26x26 κ receptor 6B73 NTS1 receptor 4XES
TM3 132 L 3.27x27 κ receptor 6B73 CCR5 7O7F
TM3 133 V 3.28x28 κ receptor 6B73 κ receptor 6B73
TM3 134 L 3.29x29 κ receptor 6B73 κ receptor 6B73
TM3 135 S 3.30x30 κ receptor 6B73 κ receptor 6B73
TM3 136 V 3.31x31 κ receptor 6B73 β1-adrenoceptor 7BU7
TM3 137 D 3.32x32 κ receptor 6B73 κ receptor 6B73
TM3 138 A 3.33x33 κ receptor 6B73 CCR6 6WWZ
TM3 139 V 3.34x34 κ receptor 6B73 CXCR2 6LFO
TM3 140 N 3.35x35 κ receptor 6B73 κ receptor 6B73
TM3 141 M 3.36x36 κ receptor 6B73 κ receptor 6B73
TM3 142 F 3.37x37 κ receptor 6B73 κ receptor 6B73
TM3 143 T 3.38x38 κ receptor 6B73 κ receptor 6B73
TM3 144 S 3.39x39 κ receptor 6B73 κ receptor 6B73
TM3 145 I 3.40x40 κ receptor 6B73 κ receptor 6B73
TM3 146 Y 3.41x41 κ receptor 6B73 V2 receptor 7KH0
TM3 147 C 3.42x42 κ receptor 6B73 GPR52 6LI3
TM3 148 L 3.43x43 κ receptor 6B73 κ receptor 6B73
TM3 149 T 3.44x44 κ receptor 6B73 κ receptor 6B73
TM3 150 V 3.45x45 κ receptor 6B73 β1-adrenoceptor 7BU7
TM3 151 L 3.46x46 κ receptor 6B73 AT1 receptor 6DO1
TM3 152 S 3.47x47 κ receptor 6B73 κ receptor 6B73
TM3 153 V 3.48x48 κ receptor 6B73 κ receptor 6B73
TM3 154 D 3.49x49 κ receptor 6B73 κ receptor 6B73
TM3 155 R 3.50x50 κ receptor 6B73 κ receptor 6B73
TM3 156 Y 3.51x51 κ receptor 6B73 κ receptor 6B73
TM3 157 V 3.52x52 κ receptor 6B73 5-HT2C receptor 6BQG
TM3 158 A 3.53x53 κ receptor 6B73 κ receptor 6B73
TM3 159 V 3.54x54 κ receptor 6B73 κ receptor 6B73
TM3 160 V 3.55x55 κ receptor 6B73 AT1 receptor 6DO1
TM3 161 H 3.56x56 κ receptor 6B73 κ receptor 6B73
ICL2 162 P 34.50x50 κ receptor 6B73 κ receptor 6B73
ICL2 163 I 34.51x51 κ receptor 6B73 5-HT2A receptor 6WHA
ICL2 164 K 34.52x52 κ receptor 6B73 κ receptor 6B73
ICL2 165 A 34.53x53 κ receptor 6B73 κ receptor 6B73
ICL2 166 A 34.54x54 κ receptor 6B73 5-HT1F receptor 7EXD
ICL2 167 R 34.55x55 κ receptor 6B73 5-HT1F receptor 7EXD
ICL2 168 Y 34.56x56 κ receptor 6B73 EP4 receptor 7D7M
ICL2 169 R 34.57x57 κ receptor 6B73 κ receptor 6B73
TM4 170 R 4.38x38 κ receptor 6B73 OT receptor 6TPK
TM4 171 P 4.39x39 κ receptor 6B73 κ receptor 6B73
TM4 172 T 4.40x40 κ receptor 6B73 CCR5 7O7F
TM4 173 V 4.41x41 κ receptor 6B73 AT1 receptor 6DO1
TM4 174 A 4.42x42 κ receptor 6B73 κ receptor 6B73
TM4 175 K 4.43x43 κ receptor 6B73 κ receptor 6B73
TM4 176 V 4.44x44 κ receptor 6B73 AT1 receptor 6DO1
TM4 177 V 4.45x45 κ receptor 6B73 μ receptor 5C1M
TM4 178 N 4.46x46 κ receptor 6B73 κ receptor 6B73
TM4 179 L 4.47x47 κ receptor 6B73 CXCR2 6LFO
TM4 180 G 4.48x48 κ receptor 6B73 FPR2/ALX 6OMM
TM4 181 V 4.49x49 κ receptor 6B73 β1-adrenoceptor 7BU7
TM4 182 W 4.50x50 κ receptor 6B73 κ receptor 6B73
TM4 183 V 4.51x51 κ receptor 6B73 δ receptor 6PT2
TM4 184 L 4.52x52 κ receptor 6B73 κ receptor 6B73
TM4 185 S 4.53x53 κ receptor 6B73 κ receptor 6B73
TM4 186 L 4.54x54 κ receptor 6B73 CXCR2 6LFO
TM4 187 L 4.55x55 κ receptor 6B73 AT1 receptor 6DO1
TM4 188 V 4.56x56 κ receptor 6B73 κ receptor 6B73
TM4 189 I 4.57x57 AT1 receptor 4ZUD BILF1 7JHJ
TM4 190 L 4.58x59 AT1 receptor 4ZUD AT1 receptor 6DO1
TM4 191 P 4.59x60 κ receptor 6B73 AT1 receptor 6DO1
TM4 192 I 4.60x61 κ receptor 6B73 κ receptor 6B73
TM4 193 V 4.61x62 κ receptor 6B73 κ receptor 6B73
TM4 194 V 4.62x63 κ receptor 6B73 5-HT2C receptor 6BQG
TM4 195 F 4.63x64 κ receptor 6B73 CCR5 7F1S
TM4 196 S 4.64x65 LPA6 receptor 5XSZ CCK1 receptor 7EZM
ECL2 197 R - κ receptor 6B73 - -
ECL2 198 T - κ receptor 6B73 κ receptor 6B73
ECL2 199 A - κ receptor 6B73 - -
ECL2 200 A - κ receptor 6B73 - -
ECL2 201 N - κ receptor 6B73 - -
ECL2 202 S - - - - -
ECL2 203 D - - - - -
ECL2 204 G - - - - -
ECL2 205 T - κ receptor 6B73 - -
ECL2 206 V - κ receptor 6B73 - -
ECL2 207 A - κ receptor 6B73 - -
ECL2 208 C 45.50x50 κ receptor 6B73 κ receptor 6B73
ECL2 209 N 45.51x51 κ receptor 6B73 - -
ECL2 210 M 45.52x52 κ receptor 6B73 AT2 receptor 5UNG
ECL2 211 L - - - - -
ECL2 212 M - - - - -
ECL2 213 P - - - - -
ECL2 214 E - - - - -
TM5 215 P 5.30x31 κ receptor 4DJH - -
TM5 216 A 5.31x32 κ receptor 4DJH FPR2/ALX 6OMM
TM5 217 Q 5.32x33 κ receptor 4DJH CCR5 7O7F
TM5 218 R 5.33x34 κ receptor 6B73 CCR6 6WWZ
TM5 219 W 5.34x35 κ receptor 6B73 κ receptor 6B73
TM5 220 L 5.35x36 κ receptor 6B73 FPR2/ALX 6OMM
TM5 221 V 5.36x37 κ receptor 6B73 5-HT1E receptor 7E33
TM5 222 G 5.37x38 κ receptor 6B73 AT1 receptor 6DO1
TM5 223 F 5.38x39 κ receptor 6B73 D2 receptor 7JVR
TM5 224 V 5.39x40 κ receptor 6B73 D2 receptor 7JVR
TM5 225 L 5.40x41 κ receptor 6B73 AT1 receptor 6DO1
TM5 226 Y 5.41x42 κ receptor 6B73 D2 receptor 7JVR
TM5 227 T 5.42x43 κ receptor 6B73 H1 receptor 7DFL
TM5 228 F 5.43x44 κ receptor 6B73 κ receptor 6B73
TM5 229 L 5.44x45 κ receptor 6B73 δ receptor 6PT2
TM5 230 M 5.45x46 κ receptor 6B73 NTS1 receptor 4XES
TM5 231 G 5.46x461 κ receptor 6B73 AT1 receptor 6DO1
TM5 232 F 5.47x47 κ receptor 6B73 κ receptor 6B73
TM5 233 L 5.48x48 κ receptor 6B73 AT1 receptor 6DO1
TM5 234 L 5.49x49 κ receptor 6B73 CCR5 7O7F
TM5 235 P 5.50x50 κ receptor 6B73 κ receptor 6B73
TM5 236 V 5.51x51 κ receptor 6B73 κ receptor 6B73
TM5 237 G 5.52x52 κ receptor 6B73 D3 receptor 7CMV
TM5 238 A 5.53x53 κ receptor 6B73 EP4 receptor 7D7M
TM5 239 I 5.54x54 κ receptor 6B73 κ receptor 6B73
TM5 240 C 5.55x55 κ receptor 6B73 M1 receptor 6OIJ
TM5 241 L 5.56x56 κ receptor 6B73 α2B-adrenoceptor 6K42
TM5 242 C 5.57x57 κ receptor 6B73 κ receptor 6B73
TM5 243 Y 5.58x58 κ receptor 6B73 κ receptor 6B73
TM5 244 V 5.59x59 κ receptor 6B73 V2 receptor 7KH0
TM5 245 L 5.60x60 κ receptor 6B73 κ receptor 6B73
TM5 246 I 5.61x61 κ receptor 6B73 AT1 receptor 6DO1
TM5 247 I 5.62x62 κ receptor 6B73 κ receptor 6B73
TM5 248 A 5.63x63 κ receptor 6B73 FPR2/ALX 6OMM
TM5 249 K 5.64x64 κ receptor 6B73 OX2 receptor 7L1V
TM5 250 M 5.65x65 κ receptor 6B73 ETB receptor 5X93
TM5 251 R 5.66x66 κ receptor 6B73 δ receptor 6PT2
TM5 252 M 5.67x67 κ receptor 6B73 PAF receptor 5ZKQ
TM5 253 V 5.68x68 κ receptor 4DJH κ receptor 4DJH
ICL3 254 A - κ receptor 6B73 - -
ICL3 255 L - - - - -
ICL3 256 K - - - - -
ICL3 257 A - - - - -
ICL3 258 G - - - - -
TM6 259 W 6.23x23 κ receptor 6B73 - -
TM6 260 Q 6.24x24 κ receptor 6B73 A1 receptor 6D9H
TM6 261 Q 6.25x25 κ receptor 6B73 5-HT2B receptor 5TUD
TM6 262 R 6.26x26 κ receptor 6B73 NTS1 receptor 5T04
TM6 263 K 6.27x27 κ receptor 6B73 - -
TM6 264 R 6.28x28 κ receptor 6B73 μ receptor 6DDF
TM6 265 S 6.29x29 κ receptor 6B73 δ receptor 6PT2
TM6 266 E 6.30x30 κ receptor 6B73 β1-adrenoceptor 7BU7
TM6 267 R 6.31x31 κ receptor 6B73 μ receptor 5C1M
TM6 268 K 6.32x32 κ receptor 6B73 β1-adrenoceptor 7BU7
TM6 269 I 6.33x33 κ receptor 6B73 κ receptor 6B73
TM6 270 T 6.34x34 κ receptor 6B73 κ receptor 6B73
TM6 271 L 6.35x35 κ receptor 6B73 NTS1 receptor 4XES
TM6 272 M 6.36x36 κ receptor 6B73 μ receptor 5C1M
TM6 273 V 6.37x37 κ receptor 6B73 κ receptor 6B73
TM6 274 M 6.38x38 κ receptor 6B73 AT1 receptor 6DO1
TM6 275 M 6.39x39 κ receptor 6B73 CysLT1 receptor 6RZ4
TM6 276 V 6.40x40 κ receptor 6B73 κ receptor 6B73
TM6 277 V 6.41x41 κ receptor 6B73 κ receptor 6B73
TM6 278 M 6.42x42 κ receptor 6B73 TP receptor 6IIV
TM6 279 V 6.43x43 κ receptor 6B73 κ receptor 6B73
TM6 280 F 6.44x44 κ receptor 6B73 κ receptor 6B73
TM6 281 V 6.45x45 κ receptor 6B73 κ receptor 6B73
TM6 282 I 6.46x46 κ receptor 6B73 D2 receptor 7JVR
TM6 283 C 6.47x47 κ receptor 6B73 κ receptor 6B73
TM6 284 W 6.48x48 κ receptor 6B73 κ receptor 6B73
TM6 285 M 6.49x49 κ receptor 6B73 CCK1 receptor 7EZM
TM6 286 P 6.50x50 κ receptor 6B73 κ receptor 6B73
TM6 287 F 6.51x51 κ receptor 6B73 β1-adrenoceptor 7BU7
TM6 288 Y 6.52x52 κ receptor 6B73 CXCR4 3ODU
TM6 289 V 6.53x53 κ receptor 6B73 AT2 receptor 5UNG
TM6 290 V 6.54x54 κ receptor 6B73 CCR5 7O7F
TM6 291 Q 6.55x55 κ receptor 6B73 V2 receptor 7KH0
TM6 292 L 6.56x56 κ receptor 6B73 κ receptor 6B73
TM6 293 V 6.57x57 κ receptor 6B73 κ receptor 6B73
TM6 294 N 6.58x58 κ receptor 6B73 CCR5 7O7F
TM6 295 V 6.59x59 κ receptor 6B73 AT1 receptor 6DO1
TM6 296 F 6.60x60 κ receptor 6B73 CCR5 7O7F
TM6 297 A 6.61x61 κ receptor 6B73 - -
ECL3 298 E - - - - -
ECL3 299 Q - κ receptor 6B73 - -
ECL3 300 D - κ receptor 6B73 - -
ECL3 301 D - κ receptor 6B73 - -
TM7 302 A 7.32x31 κ receptor 6B73 OT receptor 6TPK
TM7 303 T 7.33x32 κ receptor 6B73 AT1 receptor 6DO1
TM7 304 V 7.34x33 κ receptor 6B73 β2-adrenoceptor 3SN6
TM7 305 S 7.35x34 κ receptor 6B73 5-HT1F receptor 7EXD
TM7 306 Q 7.36x35 κ receptor 6B73 CCR5 7O7F
TM7 307 L 7.37x36 κ receptor 6B73 δ receptor 6PT2
TM7 308 S 7.38x37 κ receptor 6B73 OX2 receptor 7L1V
TM7 309 V 7.39x38 κ receptor 6B73 5-HT2B receptor 5TUD
TM7 310 I 7.40x39 κ receptor 6B73 CXCR2 6LFO
TM7 311 L 7.41x40 κ receptor 6B73 κ receptor 6B73
TM7 312 G 7.42x41 κ receptor 6B73 κ receptor 6B73
TM7 313 Y 7.43x42 κ receptor 6B73 κ receptor 6B73
TM7 314 A 7.44x43 κ receptor 6B73 β1-adrenoceptor 7BU7
TM7 315 N 7.45x45 κ receptor 6B73 κ receptor 6B73
TM7 316 S 7.46x46 κ receptor 6B73 κ receptor 6B73
TM7 317 C 7.47x47 κ receptor 6B73 μ receptor 5C1M
TM7 318 A 7.48x48 κ receptor 6B73 OX2 receptor 7L1V
TM7 319 N 7.49x49 κ receptor 6B73 κ receptor 6B73
TM7 320 P 7.50x50 κ receptor 6B73 κ receptor 6B73
TM7 321 I 7.51x51 κ receptor 6B73 CCK1 receptor 7EZM
TM7 322 L 7.52x52 κ receptor 4DJH κ receptor 4DJH
TM7 323 Y 7.53x53 κ receptor 4DJH κ receptor 4DJH
TM7 324 G 7.54x54 κ receptor 4DJH AT1 receptor 6DO1
TM7 325 F 7.55x55 κ receptor 4DJH κ receptor 4DJH
TM7 326 L 7.56x56 κ receptor 4DJH κ receptor 4DJH
H8 327 S 8.47x47 κ receptor 4DJH β1-adrenoceptor 7BU7
H8 328 D 8.48x48 κ receptor 4DJH NK1 receptor 6HLP
H8 329 N 8.49x49 κ receptor 4DJH κ receptor 4DJH
H8 330 F 8.50x50 κ receptor 4DJH κ receptor 4DJH
H8 331 K 8.51x51 κ receptor 4DJH κ receptor 4DJH
H8 332 R 8.52x52 κ receptor 4DJH κ receptor 4DJH
H8 333 S 8.53x53 κ receptor 4DJH CB2 receptor 6PT0
H8 334 F 8.54x54 κ receptor 4DJH κ receptor 4DJH
H8 335 Q 8.55x55 κ receptor 4DJH β1-adrenoceptor 7BU7
H8 336 R 8.56x56 κ receptor 4DJH α2B-adrenoceptor 6K42
H8 337 I 8.57x57 κ receptor 4DJH CXCR2 6LFO
H8 338 L 8.58x58 κ receptor 4DJH AT1 receptor 6DO1
H8 339 C 8.59x59 κ receptor 4DJH α2B-adrenoceptor 6K41
C-term 340 L - - - - -
C-term 341 S - - - - -
C-term 342 W - - - - -
C-term 343 M - - - - -
C-term 344 D - - - - -