OR1G1 (or1g1_human)

FAMILY

Class O2 (tetrapod specific odorant) Odorant receptors Odorant family 1 OR1G1

GENE

OR1G1 (OR1G2)

ORGANISM

Human (Homo sapiens)

ALT. NAMES

Olfactory receptor 1G1, Olfactory receptor 17-209, OR17-209, Olfactory receptor 1G2, Olfactory receptor OR17-8

SOURCE

SWISSPROT

SEQUENCE

N-term        
M
E
G
K
N
L
T
S
I
S
10
                   
E
C
F
L
L
G
F
S
E
Q
20
      TM1        
L
E
E
Q
K
P
L
F
G
S
30
                   
F
L
F
M
Y
L
V
T
V
A
40
                   
G
N
L
L
I
I
L
V
I
I
50
    ICL1 TM2  
T
D
T
Q
L
H
T
P
M
Y
60
                   
F
F
L
A
N
L
S
L
A
D
70
                   
A
C
F
V
S
T
T
V
P
K
80
                   
M
L
A
N
I
Q
I
Q
S
Q
90
ECL1 TM3      
A
I
S
Y
S
G
C
L
L
Q
100
                   
L
Y
F
F
M
L
F
V
M
L
110
                   
E
A
F
L
L
A
V
M
A
Y
120
                   
D
C
Y
V
A
I
C
H
P
L
130
ICL2     TM4  
H
Y
I
L
I
M
S
P
G
L
140
                   
C
I
F
L
V
S
A
S
W
I
150
                   
M
N
A
L
H
S
L
L
H
T
160
            ECL2
L
L
M
N
S
L
S
F
C
A
170
                   
N
H
E
I
P
H
F
F
C
D
180
                   
I
N
P
L
L
S
L
S
C
T
190
  TM5            
D
P
F
T
N
E
L
V
I
F
200
                   
I
T
G
G
L
T
G
L
I
C
210
                   
V
L
C
L
I
I
S
Y
T
N
220
                   
V
F
S
T
I
L
K
I
P
S
230
TM6              
A
Q
G
K
R
K
A
F
S
T
240
                   
C
S
S
H
L
S
V
V
S
L
250
                   
F
F
G
T
S
F
C
V
D
F
260
          ECL3  
S
S
P
S
T
H
S
A
Q
K
270
TM7              
D
T
V
A
S
V
M
Y
T
V
280
                   
V
T
P
M
L
N
P
F
I
Y
290
      H8          
S
L
R
N
Q
E
I
K
S
S
300
                   
L
R
K
L
I
W
V
R
K
I
310
C-term
H
S
P

LINKS

UniProt

DIAGRAMS

7TM

ICL1 T Q L H ICL1ECL1 S Q A I ECL1ICL2 P L H Y I L I M ICL2ECL2 S F C A N H E I P H F F C D I N P L L S L S C T D ECL2ICL3 I P ICL3ECL3 H S A Q ECL3N-term M E G K N L T S I S E C F L L G F S E Q L E E N-termC-term R K I H S P C-term Q K P L F G S F L F M Y L V T V A G N L L I I L V I I T D T P M Y F F L A N L S L A D A C F V S T T V P K M L A N I Q I Q S Y S G C L L Q L Y F F M L F V M L E A F L L A V M A Y D C Y V A I C H S P G L C I F L V S A S W I M N A L H S L L H T L L M N S L P F T N E L V I F I T G G L T G L I C V L C L I I S Y T N V F S T I L K S A Q G K R K A F S T C S S H L S V V S L F F G T S F C V D F S S P S T K D T V A S V M Y T V V T P M L N P F I Y S L R N Q E L R K I K S S L I W V
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

L N G A V T V L Y M F L F S G F L P K Q 1 A N L S L A D A C F V S T T V P K M L A 2 V A L L F A E L M V F L M F F Y L Q L L 3 C I F L V S A S W I M N A L H S L L H T 4 Y S I I L C L V C I L G T L G G T I F I 5 S S H L S V V S L F F G T S F C V D F S 6 F P N L M P T V V T Y M V S A V T D K 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

or1g1_human inactive,

or1g1_human active

STRUCTURES

No structures available