SST3 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SST3 receptor

SPECIES

Homo sapiens

STATE

Active

VERSION

2021-10-06

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

κ receptor (sequence similarity: 41%) PDB: 6B73
Align

TEMPLATES

6B73 (κ receptor)
4DJH (κ receptor)
6LFL (CXCR2)
7EZM (CCK1 receptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 79.2 11.4 9.4
Side-chains 31.2 54.4 14.4

Number of backbone templates: 4
Number of rotamer templates: 40

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 37 P - - - - -
N-term 38 A - - - - -
N-term 39 G - κ receptor 6B73 κ receptor 6B73
N-term 40 L - κ receptor 6B73 κ receptor 6B73
N-term 41 A - κ receptor 6B73 κ receptor 6B73
TM1 42 V 1.30x30 κ receptor 6B73 μ receptor 5C1M
TM1 43 S 1.31x31 κ receptor 6B73 CCR6 6WWZ
TM1 44 G 1.32x32 κ receptor 6B73 D4 receptor 5WIV
TM1 45 V 1.33x33 κ receptor 6B73 κ receptor 6B73
TM1 46 L 1.34x34 κ receptor 6B73 FPR2/ALX 6OMM
TM1 47 I 1.35x35 κ receptor 6B73 κ receptor 6B73
TM1 48 P 1.36x36 κ receptor 6B73 AT1 receptor 6DO1
TM1 49 L 1.37x37 κ receptor 6B73 CCK1 receptor 7EZM
TM1 50 V 1.38x38 κ receptor 6B73 κ receptor 6B73
TM1 51 Y 1.39x39 κ receptor 6B73 κ receptor 6B73
TM1 52 L 1.40x40 κ receptor 6B73 NTS1 receptor 6OSA
TM1 53 V 1.41x41 κ receptor 6B73 κ receptor 6B73
TM1 54 V 1.42x42 κ receptor 6B73 κ receptor 6B73
TM1 55 C 1.43x43 κ receptor 6B73 μ receptor 5C1M
TM1 56 V 1.44x44 κ receptor 6B73 κ receptor 6B73
TM1 57 V 1.45x45 κ receptor 6B73 κ receptor 6B73
TM1 58 G 1.46x46 κ receptor 6B73 κ receptor 6B73
TM1 59 L 1.47x47 κ receptor 6B73 κ receptor 6B73
TM1 60 L 1.48x48 κ receptor 6B73 δ receptor 6PT2
TM1 61 G 1.49x49 κ receptor 6B73 κ receptor 6B73
TM1 62 N 1.50x50 κ receptor 6B73 κ receptor 6B73
TM1 63 S 1.51x51 κ receptor 6B73 κ receptor 6B73
TM1 64 L 1.52x52 κ receptor 6B73 κ receptor 6B73
TM1 65 V 1.53x53 κ receptor 6B73 κ receptor 6B73
TM1 66 I 1.54x54 κ receptor 6B73 CCK1 receptor 7EZM
TM1 67 Y 1.55x55 κ receptor 6B73 μ receptor 5C1M
TM1 68 V 1.56x56 κ receptor 6B73 κ receptor 6B73
TM1 69 V 1.57x57 κ receptor 6B73 OX2 receptor 7L1V
TM1 70 L 1.58x58 κ receptor 6B73 CXCR2 6LFO
TM1 71 R 1.59x59 κ receptor 6B73 μ receptor 5C1M
TM1 72 H 1.60x60 κ receptor 6B73 NOP receptor 5DHH
ICL1 73 T 12.48x48 - - - -
ICL1 74 A 12.49x49 κ receptor 4DJH D2 receptor 7JVR
ICL1 75 S 12.50x50 κ receptor 4DJH - -
ICL1 76 P 12.51x51 - - - -
TM2 77 S 2.37x37 κ receptor 6B73 CXCR2 6LFM
TM2 78 V 2.38x38 κ receptor 6B73 CXCR2 6LFO
TM2 79 T 2.39x39 κ receptor 6B73 κ receptor 6B73
TM2 80 N 2.40x40 κ receptor 6B73 κ receptor 6B73
TM2 81 V 2.41x41 κ receptor 6B73 CXCR2 6LFO
TM2 82 Y 2.42x42 κ receptor 6B73 κ receptor 6B73
TM2 83 I 2.43x43 κ receptor 6B73 κ receptor 6B73
TM2 84 L 2.44x44 κ receptor 6B73 CXCR2 6LFO
TM2 85 N 2.45x45 κ receptor 6B73 κ receptor 6B73
TM2 86 L 2.46x46 κ receptor 6B73 κ receptor 6B73
TM2 87 A 2.47x47 κ receptor 6B73 κ receptor 6B73
TM2 88 L 2.48x48 κ receptor 6B73 κ receptor 6B73
TM2 89 A 2.49x49 κ receptor 6B73 κ receptor 6B73
TM2 90 D 2.50x50 κ receptor 6B73 κ receptor 6B73
TM2 91 E 2.51x51 κ receptor 6B73 - -
TM2 92 L 2.52x52 κ receptor 6B73 κ receptor 6B73
TM2 93 F 2.53x53 κ receptor 6B73 CXCR2 6LFO
TM2 94 M 2.54x54 κ receptor 6B73 - -
TM2 95 L 2.55x55 κ receptor 6B73 CXCR2 6LFO
TM2 96 G 2.56x56 κ receptor 6B73 Rhodopsin 4X1H
TM2 97 L 2.57x57 κ receptor 6B73 μ receptor 5C1M
TM2 98 P 2.58x58 κ receptor 6B73 κ receptor 6B73
TM2 99 F 2.59x59 κ receptor 6B73 κ receptor 6B73
TM2 100 L 2.60x60 κ receptor 6B73 FPR2/ALX 6OMM
TM2 101 A 2.61x61 κ receptor 6B73 CXCR2 6LFO
TM2 102 A 2.62x62 κ receptor 6B73 δ receptor 6PT2
TM2 103 Q 2.63x63 κ receptor 6B73 TP receptor 6IIV
TM2 104 N 2.64x64 κ receptor 6B73 CCK1 receptor 7EZM
TM2 105 A 2.65x65 κ receptor 6B73 AT1 receptor 6DO1
TM2 106 L 2.66x66 κ receptor 6B73 CCK1 receptor 7EZM
ECL1 107 S - - - - -
ECL1 108 Y 23.49x49 κ receptor 4DJH M2 receptor 4MQT
ECL1 109 W 23.50x50 κ receptor 4DJH κ receptor 4DJH
ECL1 110 P 23.51x51 κ receptor 4DJH κ receptor 4DJH
ECL1 111 F 23.52x52 - - - -
TM3 112 G 3.21x21 κ receptor 6B73 κ receptor 6B73
TM3 113 S 3.22x22 κ receptor 6B73 CCK1 receptor 7EZM
TM3 114 L 3.23x23 κ receptor 6B73 δ receptor 6PT2
TM3 115 M 3.24x24 κ receptor 6B73 AT2 receptor 5UNG
TM3 116 C 3.25x25 κ receptor 6B73 κ receptor 6B73
TM3 117 R 3.26x26 κ receptor 6B73 NTS1 receptor 6OSA
TM3 118 L 3.27x27 κ receptor 6B73 CCR6 6WWZ
TM3 119 V 3.28x28 κ receptor 6B73 κ receptor 6B73
TM3 120 M 3.29x29 κ receptor 6B73 D4 receptor 5WIV
TM3 121 A 3.30x30 κ receptor 6B73 AT1 receptor 6DO1
TM3 122 V 3.31x31 κ receptor 6B73 β1-adrenoceptor 7BU7
TM3 123 D 3.32x32 κ receptor 6B73 κ receptor 6B73
TM3 124 G 3.33x33 κ receptor 6B73 CCK1 receptor 7EZM
TM3 125 I 3.34x34 κ receptor 6B73 CCR6 6WWZ
TM3 126 N 3.35x35 κ receptor 6B73 κ receptor 6B73
TM3 127 Q 3.36x36 κ receptor 6B73 - -
TM3 128 F 3.37x37 κ receptor 6B73 κ receptor 6B73
TM3 129 T 3.38x38 κ receptor 6B73 κ receptor 6B73
TM3 130 S 3.39x39 κ receptor 6B73 κ receptor 6B73
TM3 131 I 3.40x40 κ receptor 6B73 κ receptor 6B73
TM3 132 F 3.41x41 κ receptor 6B73 κ receptor 6B73
TM3 133 C 3.42x42 κ receptor 6B73 GPR52 6LI3
TM3 134 L 3.43x43 κ receptor 6B73 κ receptor 6B73
TM3 135 T 3.44x44 κ receptor 6B73 κ receptor 6B73
TM3 136 V 3.45x45 κ receptor 6B73 β1-adrenoceptor 7BU7
TM3 137 M 3.46x46 κ receptor 6B73 κ receptor 6B73
TM3 138 S 3.47x47 κ receptor 6B73 κ receptor 6B73
TM3 139 V 3.48x48 κ receptor 6B73 κ receptor 6B73
TM3 140 D 3.49x49 κ receptor 6B73 κ receptor 6B73
TM3 141 R 3.50x50 κ receptor 6B73 κ receptor 6B73
TM3 142 Y 3.51x51 κ receptor 6B73 κ receptor 6B73
TM3 143 L 3.52x52 κ receptor 6B73 CXCR2 6LFO
TM3 144 A 3.53x53 κ receptor 6B73 κ receptor 6B73
TM3 145 V 3.54x54 κ receptor 6B73 κ receptor 6B73
TM3 146 V 3.55x55 κ receptor 6B73 CXCR2 6LFO
TM3 147 H 3.56x56 κ receptor 6B73 κ receptor 6B73
ICL2 148 P 34.50x50 κ receptor 6B73 κ receptor 6B73
ICL2 149 T 34.51x51 κ receptor 6B73 CXCR2 6LFO
ICL2 150 R 34.52x52 κ receptor 6B73 CXCR2 6LFO
ICL2 151 S 34.53x53 κ receptor 6B73 AT1 receptor 6DO1
ICL2 152 A 34.54x54 κ receptor 6B73 5-HT1F receptor 7EXD
ICL2 153 R 34.55x55 κ receptor 6B73 CCR6 6WWZ
ICL2 154 W 34.56x56 κ receptor 6B73 CCK1 receptor 7EZM
ICL2 155 R 34.57x57 κ receptor 6B73 κ receptor 6B73
TM4 156 T 4.38x38 κ receptor 6B73 κ receptor 6B73
TM4 157 A 4.39x39 κ receptor 6B73 OX2 receptor 7L1V
TM4 158 P 4.40x40 κ receptor 6B73 CCR6 6WWZ
TM4 159 V 4.41x41 κ receptor 6B73 AT1 receptor 6DO1
TM4 160 A 4.42x42 κ receptor 6B73 κ receptor 6B73
TM4 161 R 4.43x43 κ receptor 6B73 OX2 receptor 7L1V
TM4 162 T 4.44x44 κ receptor 6B73 5-HT1D receptor 7E32
TM4 163 V 4.45x45 κ receptor 6B73 μ receptor 5C1M
TM4 164 S 4.46x46 κ receptor 6B73 CCR5 7O7F
TM4 165 A 4.47x47 κ receptor 6B73 CCK1 receptor 7EZM
TM4 166 A 4.48x48 κ receptor 6B73 CCK1 receptor 7EZM
TM4 167 V 4.49x49 κ receptor 6B73 CCR6 6WWZ
TM4 168 W 4.50x50 κ receptor 6B73 κ receptor 6B73
TM4 169 V 4.51x51 κ receptor 6B73 δ receptor 6PT2
TM4 170 A 4.52x52 κ receptor 6B73 NTS1 receptor 6OSA
TM4 171 S 4.53x53 κ receptor 6B73 κ receptor 6B73
TM4 172 A 4.54x54 κ receptor 6B73 α2B-adrenoceptor 6K42
TM4 173 V 4.55x55 κ receptor 6B73 α2B-adrenoceptor 6K42
TM4 174 V 4.56x56 κ receptor 6B73 κ receptor 6B73
TM4 175 V 4.57x57 CXCR2 6LFL MT1 receptor 7DB6
TM4 176 L 4.58x59 CXCR2 6LFL CXCR2 6LFO
TM4 177 P 4.59x60 κ receptor 6B73 CXCR2 6LFO
TM4 178 V 4.60x61 κ receptor 6B73 CXCR2 6LFO
TM4 179 V 4.61x62 κ receptor 6B73 κ receptor 6B73
TM4 180 V 4.62x63 κ receptor 6B73 CCR6 6WWZ
TM4 181 F 4.63x64 κ receptor 6B73 CCR5 7F1S
TM4 182 S 4.64x65 CXCR2 6LFL CCK1 receptor 7EZM
ECL2 183 G - - - - -
ECL2 184 V - - - - -
ECL2 185 P - - - - -
ECL2 186 R - - - - -
ECL2 187 G - - - - -
ECL2 188 M - - - - -
ECL2 189 S - - - - -
ECL2 190 T - - - - -
ECL2 191 C 45.50x50 κ receptor 6B73 κ receptor 6B73
ECL2 192 H 45.51x51 κ receptor 6B73 - -
ECL2 193 M 45.52x52 κ receptor 6B73 AT2 receptor 5UNG
ECL2 194 Q - - - - -
ECL2 195 W - - - - -
ECL2 196 P - - - - -
ECL2 197 E - - - - -
TM5 198 P 5.30x31 κ receptor 4DJH - -
TM5 199 A 5.31x32 κ receptor 4DJH FPR2/ALX 6OMM
TM5 200 A 5.32x33 κ receptor 4DJH CXCR2 6LFO
TM5 201 A 5.33x34 κ receptor 6B73 NTS1 receptor 6OSA
TM5 202 W 5.34x35 κ receptor 6B73 κ receptor 6B73
TM5 203 R 5.35x36 κ receptor 6B73 CXCR2 6LFO
TM5 204 A 5.36x37 κ receptor 6B73 α2B-adrenoceptor 6K42
TM5 205 G 5.37x38 κ receptor 6B73 AT1 receptor 6DO1
TM5 206 F 5.38x39 κ receptor 6B73 D2 receptor 7JVR
TM5 207 I 5.39x40 κ receptor 6B73 α2B-adrenoceptor 6K42
TM5 208 I 5.40x41 κ receptor 6B73 κ receptor 6B73
TM5 209 Y 5.41x42 κ receptor 6B73 D2 receptor 7JVR
TM5 210 T 5.42x43 κ receptor 6B73 M2 receptor 4MQT
TM5 211 A 5.43x44 κ receptor 6B73 M2 receptor 4MQT
TM5 212 A 5.44x45 κ receptor 6B73 - -
TM5 213 L 5.45x46 κ receptor 6B73 AT1 receptor 6DO1
TM5 214 G 5.46x461 κ receptor 6B73 CXCR2 6LFO
TM5 215 F 5.47x47 κ receptor 6B73 κ receptor 6B73
TM5 216 F 5.48x48 κ receptor 6B73 CCR6 6WWZ
TM5 217 G 5.49x49 κ receptor 6B73 Y1 receptor 5ZBH
TM5 218 P 5.50x50 κ receptor 6B73 κ receptor 6B73
TM5 219 L 5.51x51 κ receptor 6B73 CXCR2 6LFO
TM5 220 L 5.52x52 κ receptor 6B73 κ receptor 6B73
TM5 221 V 5.53x53 κ receptor 6B73 CCK1 receptor 7EZM
TM5 222 I 5.54x54 κ receptor 6B73 κ receptor 6B73
TM5 223 C 5.55x55 κ receptor 6B73 M1 receptor 6OIJ
TM5 224 L 5.56x56 κ receptor 6B73 OX2 receptor 7L1V
TM5 225 C 5.57x57 κ receptor 6B73 κ receptor 6B73
TM5 226 Y 5.58x58 κ receptor 6B73 κ receptor 6B73
TM5 227 L 5.59x59 κ receptor 6B73 OX2 receptor 7L1V
TM5 228 L 5.60x60 κ receptor 6B73 κ receptor 6B73
TM5 229 I 5.61x61 κ receptor 6B73 AT1 receptor 6DO1
TM5 230 V 5.62x62 κ receptor 6B73 CCR6 6WWZ
TM5 231 V 5.63x63 κ receptor 6B73 D3 receptor 7CMV
TM5 232 K 5.64x64 κ receptor 6B73 OX2 receptor 7L1V
TM5 233 V 5.65x65 κ receptor 6B73 H1 receptor 7DFL
TM5 234 R 5.66x66 κ receptor 6B73 δ receptor 6PT2
TM5 235 S 5.67x67 κ receptor 6B73 κ receptor 6B73
TM5 236 A 5.68x68 CCK1 receptor 7EZM AT1 receptor 6DO1
TM5 237 G 5.69x69 CCK1 receptor 7EZM FPR2/ALX 6OMM
TM5 238 R 5.70x70 CCK1 receptor 7EZM D3 receptor 7CMV
TM5 239 R 5.71x71 CCK1 receptor 7EZM D2 receptor 7JVR
TM5 240 V 5.72x72 CCK1 receptor 7EZM D2 receptor 7JVR
ICL3 241 W - κ receptor 6B73 - -
ICL3 242 A - - - - -
ICL3 243 P - - - - -
ICL3 244 S - - - - -
ICL3 245 C - - - - -
TM6 246 Q 6.24x24 κ receptor 6B73 A1 receptor 6D9H
TM6 247 R 6.25x25 κ receptor 6B73 LPA1 receptor 4Z35
TM6 248 R 6.26x26 κ receptor 6B73 NTS1 receptor 6OSA
TM6 249 R 6.27x27 κ receptor 6B73 AT2 receptor 5UNG
TM6 250 R 6.28x28 κ receptor 6B73 μ receptor 6DDF
TM6 251 S 6.29x29 κ receptor 6B73 δ receptor 6PT2
TM6 252 E 6.30x30 κ receptor 6B73 α2B-adrenoceptor 6K42
TM6 253 R 6.31x31 κ receptor 6B73 μ receptor 5C1M
TM6 254 R 6.32x32 κ receptor 6B73 μ receptor 5C1M
TM6 255 V 6.33x33 κ receptor 6B73 CCK1 receptor 7EZM
TM6 256 T 6.34x34 κ receptor 6B73 κ receptor 6B73
TM6 257 R 6.35x35 κ receptor 6B73 κ receptor 6B73
TM6 258 M 6.36x36 κ receptor 6B73 μ receptor 5C1M
TM6 259 V 6.37x37 κ receptor 6B73 κ receptor 6B73
TM6 260 V 6.38x38 κ receptor 6B73 CB1 receptor 6N4B
TM6 261 A 6.39x39 κ receptor 6B73 CXCR2 6LFO
TM6 262 V 6.40x40 κ receptor 6B73 κ receptor 6B73
TM6 263 V 6.41x41 κ receptor 6B73 κ receptor 6B73
TM6 264 A 6.42x42 κ receptor 6B73 κ receptor 6B73
TM6 265 L 6.43x43 κ receptor 6B73 CCK1 receptor 7EZM
TM6 266 F 6.44x44 κ receptor 6B73 κ receptor 6B73
TM6 267 V 6.45x45 κ receptor 6B73 κ receptor 6B73
TM6 268 L 6.46x46 κ receptor 6B73 CXCR2 6LFO
TM6 269 C 6.47x47 κ receptor 6B73 κ receptor 6B73
TM6 270 W 6.48x48 κ receptor 6B73 κ receptor 6B73
TM6 271 M 6.49x49 κ receptor 6B73 CCK1 receptor 7EZM
TM6 272 P 6.50x50 κ receptor 6B73 κ receptor 6B73
TM6 273 F 6.51x51 κ receptor 6B73 α2B-adrenoceptor 6K42
TM6 274 Y 6.52x52 κ receptor 6B73 CXCR4 3ODU
TM6 275 V 6.53x53 κ receptor 6B73 AT2 receptor 5UNG
TM6 276 L 6.54x54 κ receptor 6B73 OX2 receptor 7L1V
TM6 277 N 6.55x55 κ receptor 6B73 CCK1 receptor 7EZM
TM6 278 I 6.56x56 κ receptor 6B73 μ receptor 5C1M
TM6 279 V 6.57x57 κ receptor 6B73 κ receptor 6B73
TM6 280 N 6.58x58 κ receptor 6B73 D2 receptor 7JVR
TM6 281 V 6.59x59 κ receptor 6B73 AT1 receptor 6DO1
TM6 282 V 6.60x60 κ receptor 6B73 OX2 receptor 7L1V
TM6 283 C 6.61x61 κ receptor 6B73 α2B-adrenoceptor 6K42
ECL3 284 P - - - - -
ECL3 285 L - κ receptor 6B73 - -
ECL3 286 P - κ receptor 6B73 - -
ECL3 287 E - κ receptor 6B73 - -
TM7 288 E 7.28x27 κ receptor 6B73 - -
TM7 289 P 7.29x28 κ receptor 6B73 δ receptor 6PT2
TM7 290 A 7.30x29 κ receptor 6B73 κ receptor 6B73
TM7 291 F 7.31x30 κ receptor 6B73 - -
TM7 292 F 7.32x31 κ receptor 6B73 P2Y12 receptor 4NTJ
TM7 293 G 7.33x32 κ receptor 6B73 α2B-adrenoceptor 6K41
TM7 294 L 7.34x33 κ receptor 6B73 α2B-adrenoceptor 6K42
TM7 295 Y 7.35x34 κ receptor 6B73 κ receptor 6B73
TM7 296 F 7.36x35 κ receptor 6B73 GPR52 6LI3
TM7 297 L 7.37x36 κ receptor 6B73 δ receptor 6PT2
TM7 298 V 7.38x37 κ receptor 6B73 D4 receptor 5WIV
TM7 299 V 7.39x38 κ receptor 6B73 5-HT2B receptor 5TUD
TM7 300 A 7.40x39 κ receptor 6B73 κ receptor 6B73
TM7 301 L 7.41x40 κ receptor 6B73 κ receptor 6B73
TM7 302 P 7.42x41 κ receptor 6B73 - -
TM7 303 Y 7.43x42 κ receptor 6B73 κ receptor 6B73
TM7 304 A 7.44x43 κ receptor 6B73 OX2 receptor 7L1V
TM7 305 N 7.45x45 κ receptor 6B73 κ receptor 6B73
TM7 306 S 7.46x46 κ receptor 6B73 κ receptor 6B73
TM7 307 C 7.47x47 κ receptor 6B73 μ receptor 5C1M
TM7 308 A 7.48x48 κ receptor 6B73 OX2 receptor 7L1V
TM7 309 N 7.49x49 κ receptor 6B73 κ receptor 6B73
TM7 310 P 7.50x50 κ receptor 6B73 κ receptor 6B73
TM7 311 I 7.51x51 κ receptor 6B73 CCK1 receptor 7EZM
TM7 312 L 7.52x52 κ receptor 4DJH κ receptor 4DJH
TM7 313 Y 7.53x53 κ receptor 4DJH κ receptor 4DJH
TM7 314 G 7.54x54 κ receptor 4DJH AT1 receptor 6DO1
TM7 315 F 7.55x55 κ receptor 4DJH κ receptor 4DJH
TM7 316 L 7.56x56 κ receptor 4DJH κ receptor 4DJH
H8 317 S 8.47x47 κ receptor 4DJH OX2 receptor 7L1V
H8 318 Y 8.48x48 κ receptor 4DJH - -
H8 319 R 8.49x49 κ receptor 4DJH CCK1 receptor 7EZM
H8 320 F 8.50x50 κ receptor 4DJH κ receptor 4DJH
H8 321 K 8.51x51 κ receptor 4DJH κ receptor 4DJH
H8 322 Q 8.52x52 κ receptor 4DJH AT2 receptor 5UNG
H8 323 G 8.53x53 κ receptor 4DJH CXCR2 6LFO
H8 324 F 8.54x54 κ receptor 4DJH κ receptor 4DJH
H8 325 R 8.55x55 κ receptor 4DJH α2B-adrenoceptor 6K42
H8 326 R 8.56x56 κ receptor 4DJH α2B-adrenoceptor 6K42
H8 327 V 8.57x57 κ receptor 4DJH AT2 receptor 5UNG
H8 328 L 8.58x58 κ receptor 4DJH CXCR2 6LFO
H8 329 L 8.59x59 κ receptor 4DJH M4 receptor 5DSG
C-term 330 R - - - - -
C-term 331 P - - - - -
C-term 332 S - - - - -
C-term 333 R - - - - -
C-term 334 R - - - - -