Olfactory receptor 2T11 homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Inactive

VERSION

2021-02-08

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

NOP receptor (sequence similarity: 36%) PDB: 5DHG

TEMPLATES

5DHG (NOP receptor)
6W25 (MC4 receptor)
3RZE (H1 receptor)
5C1M (μ receptor)
4BUO (NTS1 receptor)
7L0R (NTS1 receptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 76.1 6.8 17.1
Side-chains 15.4 56.7 28.0

Number of backbone templates: 6
Number of rotamer templates: 57

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 13 G - - - -
N-term 14 L - - - -
N-term 15 L - - - -
N-term 16 V - - - -
N-term 17 N NOP receptor 5DHG NOP receptor 5DHG
TM1 18 S 1.29x29 NOP receptor 5DHG A1 receptor 5UEN
TM1 19 E 1.30x30 NOP receptor 5DHG - -
TM1 20 A 1.31x31 NOP receptor 5DHG CCR5 5UIW
TM1 21 A 1.32x32 NOP receptor 5DHG μ receptor 4DKL
TM1 22 G 1.33x33 NOP receptor 5DHG - -
TM1 23 I 1.34x34 NOP receptor 5DHG κ receptor 4DJH
TM1 24 V 1.35x35 NOP receptor 5DHG LPA1 receptor 4Z35
TM1 25 F 1.36x36 NOP receptor 5DHG FFA1 receptor 5TZY
TM1 26 T 1.37x37 NOP receptor 5DHG M4 receptor 6KP6
TM1 27 V 1.38x38 NOP receptor 5DHG H1 receptor 3RZE
TM1 28 I 1.39x39 NOP receptor 5DHG 5-HT2C receptor 6BQH
TM1 29 L 1.40x40 NOP receptor 5DHG NOP receptor 5DHG
TM1 30 A 1.41x41 NOP receptor 5DHG NOP receptor 5DHG
TM1 31 V 1.42x42 NOP receptor 5DHG NOP receptor 5DHG
TM1 32 F 1.43x43 NOP receptor 5DHG ghrelin receptor 6KO5
TM1 33 L 1.44x44 NOP receptor 5DHG H1 receptor 3RZE
TM1 34 G 1.45x45 NOP receptor 5DHG NOP receptor 5DHG
TM1 35 A 1.46x46 NOP receptor 5DHG OT receptor 6TPK
TM1 36 V 1.47x47 NOP receptor 5DHG H1 receptor 3RZE
TM1 37 T 1.48x48 NOP receptor 5DHG GnRH1 receptor 7BR3
TM1 38 A 1.49x49 NOP receptor 5DHG LPA1 receptor 4Z35
TM1 39 N 1.50x50 NOP receptor 5DHG NOP receptor 5DHG
TM1 40 L 1.51x51 NOP receptor 5DHG LPA1 receptor 4Z35
TM1 41 V 1.52x52 NOP receptor 5DHG NTS1 receptor 4BUO
TM1 42 M 1.53x53 NOP receptor 5DHG - -
TM1 43 I 1.54x54 NOP receptor 5DHG 5-HT2C receptor 6BQH
TM1 44 F 1.55x55 NOP receptor 5DHG κ receptor 6VI4
TM1 45 L 1.56x56 NOP receptor 5DHG CB2 receptor 5ZTY
TM1 46 I 1.57x57 NOP receptor 5DHG NOP receptor 5DHG
TM1 47 Q 1.58x58 NOP receptor 5DHG GnRH1 receptor 7BR3
TM1 48 V 1.59x59 NOP receptor 5DHG LPA1 receptor 4Z35
TM1 49 D 1.60x60 NOP receptor 5DHG - -
ICL1 50 S 12.48x48 - - - -
ICL1 51 R 12.49x49 MC4 receptor 6W25 LPA1 receptor 4Z36
ICL1 52 L 12.50x50 MC4 receptor 6W25 MC4 receptor 6W25
ICL1 53 H 12.51x51 - - - -
TM2 54 T 2.37x37 NOP receptor 5DHG NOP receptor 5DHG
TM2 55 P 2.38x38 NOP receptor 5DHG LPA1 receptor 4Z35
TM2 56 M 2.39x39 NOP receptor 5DHG GnRH1 receptor 7BR3
TM2 57 Y 2.40x40 NOP receptor 5DHG LPA1 receptor 4Z35
TM2 58 F 2.41x41 NOP receptor 5DHG OT receptor 6TPK
TM2 59 L 2.42x42 NOP receptor 5DHG LPA1 receptor 4Z35
TM2 60 L 2.43x43 NOP receptor 5DHG ghrelin receptor 6KO5
TM2 61 S 2.44x44 NOP receptor 5DHG ghrelin receptor 6KO5
TM2 62 Q 2.45x45 NOP receptor 5DHG - -
TM2 63 L 2.46x46 NOP receptor 5DHG NOP receptor 5DHG
TM2 64 S 2.47x47 NOP receptor 5DHG H1 receptor 3RZE
TM2 65 I 2.48x48 NOP receptor 5DHG 5-HT2C receptor 6BQH
TM2 66 M 2.49x49 NOP receptor 5DHG - -
TM2 67 D 2.50x50 NOP receptor 5DHG NOP receptor 5DHG
TM2 68 T 2.51x51 NOP receptor 5DHG NOP receptor 5DHG
TM2 69 L 2.52x52 NOP receptor 5DHG NOP receptor 5DHG
TM2 70 F 2.53x53 NOP receptor 5DHG AT1 receptor 4ZUD
TM2 71 I 2.54x54 NOP receptor 5DHG ETB receptor 5X93
TM2 72 C 2.55x55 H1 receptor 3RZE CysLT1 receptor 6RZ4
TM2 73 T 2.56x551 H1 receptor 3RZE OX2 receptor 5WS3
TM2 74 T 2.57x56 H1 receptor 3RZE H1 receptor 3RZE
TM2 75 V 2.58x57 NOP receptor 5DHG β2-adrenoceptor 5JQH
TM2 76 P 2.59x58 NOP receptor 5DHG NOP receptor 5DHG
TM2 77 K 2.60x59 NOP receptor 5DHG - -
TM2 78 L 2.61x60 NOP receptor 5DHG LPA1 receptor 4Z35
TM2 79 L 2.62x61 NOP receptor 5DHG ghrelin receptor 6KO5
TM2 80 A 2.63x62 NOP receptor 5DHG δ receptor 4EJ4
TM2 81 D 2.64x63 NOP receptor 5DHG NOP receptor 5DHG
TM2 82 M 2.65x64 NOP receptor 5DHG FPR2/ALX 6LW5
TM2 83 V 2.66x65 NOP receptor 5DHG M2 receptor 5ZKC
ECL1 84 S - - - -
ECL1 85 K - - - -
ECL1 86 E - - - -
ECL1 87 K - - - -
ECL1 88 I - - - -
ECL1 89 I - - - -
TM3 90 S 3.21x21 NOP receptor 5DHG CB2 receptor 5ZTY
TM3 91 F 3.22x22 NOP receptor 5DHG A1 receptor 5UEN
TM3 92 V 3.23x23 NOP receptor 5DHG κ receptor 6VI4
TM3 93 A 3.24x24 NOP receptor 5DHG C5a1 receptor 5O9H
TM3 94 C 3.25x25 NOP receptor 5DHG NOP receptor 5DHG
TM3 95 G 3.26x26 NOP receptor 5DHG α2C-adrenoceptor 6KUW
TM3 96 I 3.27x27 NOP receptor 5DHG μ receptor 4DKL
TM3 97 Q 3.28x28 NOP receptor 5DHG Rhodopsin 4ZWJ
TM3 98 I 3.29x29 NOP receptor 5DHG NOP receptor 5DHG
TM3 99 F 3.30x30 NOP receptor 5DHG ghrelin receptor 6KO5
TM3 100 L 3.31x31 NOP receptor 5DHG LPA1 receptor 4Z35
TM3 101 Y 3.32x32 NOP receptor 5DHG CCR5 5UIW
TM3 102 L 3.33x33 NOP receptor 5DHG A1 receptor 5UEN
TM3 103 T 3.34x34 NOP receptor 5DHG LPA1 receptor 4Z35
TM3 104 M 3.35x35 NOP receptor 5DHG D2 receptor 6CM4
TM3 105 I 3.36x36 NOP receptor 5DHG NK1 receptor 6HLP
TM3 106 G 3.37x37 NOP receptor 5DHG ETB receptor 5X93
TM3 107 S 3.38x38 NOP receptor 5DHG A1 receptor 5UEN
TM3 108 E 3.39x39 NOP receptor 5DHG - -
TM3 109 F 3.40x40 NOP receptor 5DHG - -
TM3 110 F 3.41x41 NOP receptor 5DHG NOP receptor 5DHG
TM3 111 L 3.42x42 NOP receptor 5DHG C5a1 receptor 5O9H
TM3 112 L 3.43x43 NOP receptor 5DHG NOP receptor 5DHG
TM3 113 G 3.44x44 NOP receptor 5DHG FPR2/ALX 6LW5
TM3 114 L 3.45x45 NOP receptor 5DHG OT receptor 6TPK
TM3 115 M 3.46x46 NOP receptor 5DHG NOP receptor 5DHG
TM3 116 A 3.47x47 NOP receptor 5DHG LPA1 receptor 4Z35
TM3 117 Y 3.48x48 NOP receptor 5DHG PAF receptor 5ZKQ
TM3 118 D 3.49x49 NOP receptor 5DHG NOP receptor 5DHG
TM3 119 C 3.50x50 NOP receptor 5DHG - -
TM3 120 Y 3.51x51 NOP receptor 5DHG NOP receptor 5DHG
TM3 121 V 3.52x52 NOP receptor 5DHG NOP receptor 5DHG
TM3 122 A 3.53x53 NOP receptor 5DHG NOP receptor 5DHG
TM3 123 V 3.54x54 NOP receptor 5DHG μ receptor 4DKL
TM3 124 C 3.55x55 NOP receptor 5DHG NOP receptor 5DHG
TM3 125 N 3.56x56 NOP receptor 5DHG 5-HT2A receptor 6A94
ICL2 126 P 34.50x50 - - - -
ICL2 127 L 34.51x51 μ receptor 5C1M ghrelin receptor 6KO5
ICL2 128 R 34.52x52 μ receptor 5C1M ghrelin receptor 6KO5
ICL2 129 Y 34.53x53 μ receptor 5C1M A1 receptor 5UEN
ICL2 130 P 34.54x54 μ receptor 5C1M M2 receptor 5ZKC
ICL2 131 V 34.55x55 μ receptor 5C1M ghrelin receptor 6KO5
ICL2 132 L 34.56x56 μ receptor 5C1M A2A receptor 3VG9
ICL2 133 M 34.57x57 - - - -
TM4 134 N 4.38x38 NOP receptor 5DHG Y1 receptor 5ZBH
TM4 135 R 4.39x39 NOP receptor 5DHG 5-HT2C receptor 6BQH
TM4 136 K 4.40x40 NOP receptor 5DHG M2 receptor 5ZKC
TM4 137 K 4.41x41 NOP receptor 5DHG NOP receptor 5DHG
TM4 138 C 4.42x42 NOP receptor 5DHG - -
TM4 139 L 4.43x43 NOP receptor 5DHG MT1 receptor 6ME2
TM4 140 L 4.44x44 NOP receptor 5DHG ghrelin receptor 6KO5
TM4 141 L 4.45x45 NOP receptor 5DHG C5a1 receptor 5O9H
TM4 142 A 4.46x46 NOP receptor 5DHG - -
TM4 143 A 4.47x47 NOP receptor 5DHG 5-HT2C receptor 6BQH
TM4 144 G 4.48x48 NOP receptor 5DHG H1 receptor 3RZE
TM4 145 A 4.49x49 NOP receptor 5DHG H1 receptor 3RZE
TM4 146 W 4.50x50 NOP receptor 5DHG NOP receptor 5DHG
TM4 147 F 4.51x51 NOP receptor 5DHG H1 receptor 3RZE
TM4 148 G 4.52x52 NOP receptor 5DHG OT receptor 6TPK
TM4 149 G 4.53x53 NOP receptor 5DHG - -
TM4 150 S 4.54x54 NOP receptor 5DHG NOP receptor 5DHG
TM4 151 L 4.55x55 NOP receptor 5DHG H1 receptor 3RZE
TM4 152 D 4.56x56 NOP receptor 5DHG - -
TM4 153 G 4.57x57 NOP receptor 5DHG NOP receptor 5DHG
TM4 154 F 4.58x58 NOP receptor 5DHG β2-adrenoceptor 5JQH
TM4 155 L 4.59x59 NOP receptor 5DHG MT1 receptor 6ME2
TM4 156 L 4.60x60 NOP receptor 5DHG - -
TM4 157 T 4.61x61 NOP receptor 5DHG CCR6 6WWZ
TM4 158 P 4.62x62 NOP receptor 5DHG 5-HT2C receptor 6BQH
TM4 159 I 4.63x63 NOP receptor 5DHG AT1 receptor 4ZUD
TM4 160 T 4.64x64 NOP receptor 5DHG P2Y12 receptor 4PXZ
ECL2 161 M - - - -
ECL2 162 N - - - -
ECL2 163 V - - - -
ECL2 164 P - - - -
ECL2 165 Y - - - -
ECL2 166 C - - - -
ECL2 167 G - - - -
ECL2 168 S - - - -
ECL2 169 R - - - -
ECL2 170 S - - - -
ECL2 171 I - - - -
ECL2 172 N - - - -
ECL2 173 H - - - -
ECL2 174 F - - - -
ECL2 175 F - - - -
ECL2 176 C - - - -
ECL2 177 E - - - -
ECL2 178 I - - - -
ECL2 179 P - - - -
ECL2 180 A - - - -
ECL2 181 V - - - -
ECL2 182 L - - - -
ECL2 183 K - - - -
ECL2 184 L - - - -
ECL2 185 A - - - -
ECL2 186 C 45.50x50 NOP receptor 5DHG NOP receptor 5DHG
ECL2 187 A 45.51x51 NOP receptor 5DHG AT1 receptor 4ZUD
ECL2 188 D 45.52x52 NOP receptor 5DHG Y1 receptor 5ZBH
ECL2 189 T - - - -
ECL2 190 S NTS1 receptor 4BUO - -
ECL2 191 L - - - -
TM5 192 Y 5.35x36 NOP receptor 5DHG P2Y1 receptor 4XNW
TM5 193 E 5.36x37 NOP receptor 5DHG CB1 receptor 5U09
TM5 194 T 5.37x38 NOP receptor 5DHG M3 receptor 5ZHP
TM5 195 L 5.38x39 NOP receptor 5DHG μ receptor 4DKL
TM5 196 M 5.39x40 NOP receptor 5DHG A1 receptor 5UEN
TM5 197 Y 5.40x41 NOP receptor 5DHG EP4 receptor 5YWY
TM5 198 I 5.41x42 NOP receptor 5DHG 5-HT2C receptor 6BQH
TM5 199 C 5.42x43 NOP receptor 5DHG S1P1 receptor 3V2Y
TM5 200 C 5.43x44 NOP receptor 5DHG α2C-adrenoceptor 6KUW
TM5 201 V 5.44x45 NOP receptor 5DHG C5a1 receptor 5O9H
TM5 202 L 5.45x46 NOP receptor 5DHG C5a1 receptor 5O9H
TM5 203 M 5.46x461 NOP receptor 5DHG P2Y1 receptor 4XNW
TM5 204 L 5.47x47 NOP receptor 5DHG CCR5 5UIW
TM5 205 L 5.48x48 NOP receptor 5DHG LPA1 receptor 4Z35
TM5 206 I 5.49x49 NOP receptor 5DHG κ receptor 6VI4
TM5 207 P 5.50x50 NOP receptor 5DHG NOP receptor 5DHG
TM5 208 I 5.51x51 NOP receptor 5DHG δ receptor 4EJ4
TM5 209 S 5.52x52 NOP receptor 5DHG M5 receptor 6OL9
TM5 210 I 5.53x53 NOP receptor 5DHG μ receptor 4DKL
TM5 211 I 5.54x54 NOP receptor 5DHG NOP receptor 5DHG
TM5 212 S 5.55x55 NOP receptor 5DHG NOP receptor 5DHG
TM5 213 T 5.56x56 NOP receptor 5DHG OT receptor 6TPK
TM5 214 S 5.57x57 NOP receptor 5DHG AT1 receptor 4ZUD
TM5 215 Y 5.58x58 NOP receptor 5DHG NOP receptor 5DHG
TM5 216 S 5.59x59 NOP receptor 5DHG NOP receptor 5DHG
TM5 217 L 5.60x60 NOP receptor 5DHG NOP receptor 5DHG
TM5 218 I 5.61x61 NOP receptor 5DHG LPA1 receptor 4Z35
TM5 219 L 5.62x62 NOP receptor 5DHG δ receptor 4EJ4
TM5 220 L 5.63x63 NOP receptor 5DHG μ receptor 4DKL
TM5 221 T 5.64x64 NOP receptor 5DHG GnRH1 receptor 7BR3
TM5 222 I 5.65x65 NOP receptor 5DHG A1 receptor 5UEN
TM5 223 H 5.66x66 NTS1 receptor 7L0R CB2 receptor 5ZTY
TM5 224 R 5.67x67 NTS1 receptor 7L0R β2-adrenoceptor 5JQH
TM5 225 M 5.68x68 NTS1 receptor 7L0R NTS1 receptor 7L0R
TM5 226 P 5.69x69 NTS1 receptor 7L0R - -
TM5 227 S 5.70x70 NTS1 receptor 7L0R - -
TM5 228 A 5.71x71 NTS1 receptor 7L0R EP3 receptor 6AK3
TM5 229 E 5.72x72 NTS1 receptor 7L0R GPR52 6LI3
ICL3 230 G - - - -
ICL3 231 R - - - -
TM6 232 K 6.23x23 NOP receptor 5DHG - -
TM6 233 K 6.24x24 NOP receptor 5DHG δ receptor 4RWD
TM6 234 A 6.25x25 NOP receptor 5DHG α2B-adrenoceptor 6K42
TM6 235 F 6.26x26 NOP receptor 5DHG - -
TM6 236 T 6.27x27 NOP receptor 5DHG D4 receptor 6IQL
TM6 237 T 6.28x28 NOP receptor 5DHG α2B-adrenoceptor 6K41
TM6 238 C 6.29x29 NOP receptor 5DHG - -
TM6 239 S 6.30x30 NOP receptor 5DHG C5a1 receptor 6C1R
TM6 240 S 6.31x31 NOP receptor 5DHG FPR2/ALX 6OMM
TM6 241 H 6.32x32 NOP receptor 5DHG A2A receptor 3VG9
TM6 242 L 6.33x33 NOP receptor 5DHG LPA1 receptor 4Z35
TM6 243 T 6.34x34 NOP receptor 5DHG NOP receptor 5DHG
TM6 244 V 6.35x35 NOP receptor 5DHG MT1 receptor 6ME2
TM6 245 V 6.36x36 NOP receptor 5DHG 5-HT2C receptor 6BQH
TM6 246 S 6.37x37 NOP receptor 5DHG - -
TM6 247 I 6.38x38 NOP receptor 5DHG S1P1 receptor 3V2Y
TM6 248 F 6.39x39 NOP receptor 5DHG H1 receptor 3RZE
TM6 249 Y 6.40x40 NOP receptor 5DHG Rhodopsin 4ZWJ
TM6 250 G 6.41x41 NOP receptor 5DHG - -
TM6 251 A 6.42x42 NOP receptor 5DHG NOP receptor 5DHG
TM6 252 A 6.43x43 NOP receptor 5DHG LPA1 receptor 4Z35
TM6 253 F 6.44x44 NOP receptor 5DHG NOP receptor 5DHG
TM6 254 Y 6.45x45 NOP receptor 5DHG GPR52 6LI1
TM6 255 T 6.46x46 NOP receptor 5DHG - -
TM6 256 Y 6.47x47 NOP receptor 5DHG - -
TM6 257 V 6.48x48 NOP receptor 5DHG FFA1 receptor 5TZY
TM6 258 L 6.49x49 NOP receptor 5DHG ghrelin receptor 6KO5
TM6 259 P 6.50x50 NOP receptor 5DHG NOP receptor 5DHG
TM6 260 Q 6.51x51 NOP receptor 5DHG - -
TM6 261 S 6.52x52 NOP receptor 5DHG OX1 receptor 6TO7
TM6 262 F 6.53x53 NOP receptor 5DHG MT1 receptor 6ME2
TM6 263 H 6.54x54 NOP receptor 5DHG MC4 receptor 6W25
ECL3 264 T - - - -
ECL3 265 P - - - -
TM7 266 E 7.32x31 NOP receptor 5DHG H1 receptor 3RZE
TM7 267 Q 7.33x32 NOP receptor 5DHG NK1 receptor 6HLP
TM7 268 D 7.34x33 NOP receptor 5DHG - -
TM7 269 K 7.35x34 NOP receptor 5DHG CCR6 6WWZ
TM7 270 V 7.36x35 NOP receptor 5DHG MT1 receptor 6ME2
TM7 271 V 7.37x36 NOP receptor 5DHG ghrelin receptor 6KO5
TM7 272 S 7.38x37 NOP receptor 5DHG ghrelin receptor 6KO5
TM7 273 A 7.39x38 NOP receptor 5DHG Rhodopsin 6I9K
TM7 274 F 7.40x39 NOP receptor 5DHG A1 receptor 5UEN
TM7 275 Y 7.41x40 NOP receptor 5DHG - -
TM7 276 T 7.42x41 NOP receptor 5DHG A1 receptor 5UEN
TM7 277 I 7.43x42 NOP receptor 5DHG CXCR2 6LFL
TM7 278 V 7.44x43 NOP receptor 5DHG NOP receptor 5DHG
TM7 279 T 7.45x45 NOP receptor 5DHG - -
TM7 280 P 7.46x46 NOP receptor 5DHG GnRH1 receptor 7BR3
TM7 281 M 7.47x47 NOP receptor 5DHG CB2 receptor 5ZTY
TM7 282 L 7.48x48 NOP receptor 5DHG NOP receptor 5DHG
TM7 283 N 7.49x49 NOP receptor 5DHG NOP receptor 5DHG
TM7 284 P 7.50x50 NOP receptor 5DHG NOP receptor 5DHG
TM7 285 L 7.51x51 NOP receptor 5DHG H1 receptor 3RZE
TM7 286 I 7.52x52 NOP receptor 5DHG LPA1 receptor 4Z35
TM7 287 Y 7.53x53 NOP receptor 5DHG NOP receptor 5DHG
TM7 288 S 7.54x54 NOP receptor 5DHG LPA1 receptor 4Z35
TM7 289 L 7.55x55 NOP receptor 5DHG H1 receptor 3RZE
TM7 290 R 7.56x56 NOP receptor 5DHG LPA1 receptor 4Z35
H8 291 N 8.47x47 NOP receptor 5DHG H1 receptor 3RZE
H8 292 K 8.48x48 NOP receptor 5DHG LPA1 receptor 4Z35
H8 293 D 8.49x49 NOP receptor 5DHG β2-adrenoceptor 5JQH
H8 294 V 8.50x50 NOP receptor 5DHG EP4 receptor 5YWY
H8 295 I 8.51x51 NOP receptor 5DHG - -
H8 296 G 8.52x52 NOP receptor 5DHG - -
H8 297 A 8.53x53 NOP receptor 5DHG ghrelin receptor 6KO5
H8 298 F 8.54x54 NOP receptor 5DHG NOP receptor 5DHG
H8 299 K 8.55x55 NOP receptor 5DHG - -
H8 300 K 8.56x56 MC4 receptor 6W25 A1 receptor 5UEN
C-term 301 V - - - -
C-term 302 F - - - -
C-term 303 A - - - -
C-term 304 C - - - -
C-term 305 C - - - -