TAS2R1 (ta2r1_human)
FAMILY
Class T2 (Taste 2) Sensory receptors Taste 2 receptors TAS2R1
GENE
TAS2R1
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Taste receptor type 2 member 1, T2R1, Taste receptor family B member 7, TRB7
SOURCE
SWISSPROT
SEQUENCE
N-term | TM1 | ||||||||
M
|
L
|
E
|
S
|
H
|
L
|
I
|
I
|
Y
|
F
|
10 |
L
|
L
|
A
|
V
|
I
|
Q
|
F
|
L
|
L
|
G
|
20 |
I
|
F
|
T
|
N
|
G
|
I
|
I
|
V
|
V
|
V
|
30 |
N
|
G
|
I
|
D
|
L
|
I
|
K
|
H
|
R
|
K
|
40 |
ICL1 | TM2 | ||||||||
M
|
A
|
P
|
L
|
D
|
L
|
L
|
L
|
S
|
C
|
50 |
L
|
A
|
V
|
S
|
R
|
I
|
F
|
L
|
Q
|
L
|
60 |
F
|
I
|
F
|
Y
|
V
|
N
|
V
|
I
|
V
|
I
|
70 |
ECL1 | TM3 | ||||||||
F
|
F
|
I
|
E
|
F
|
I
|
M
|
C
|
S
|
A
|
80 |
N
|
C
|
A
|
I
|
L
|
L
|
F
|
I
|
N
|
E
|
90 |
L
|
E
|
L
|
W
|
L
|
A
|
T
|
W
|
L
|
G
|
100 |
V
|
F
|
Y
|
C
|
A
|
K
|
V
|
A
|
S
|
V
|
110 |
ICL2 | |||||||||
R
|
H
|
P
|
L
|
F
|
I
|
W
|
L
|
K
|
M
|
120 |
TM4 | |||||||||
R
|
I
|
S
|
K
|
L
|
V
|
P
|
W
|
M
|
I
|
130 |
L
|
G
|
S
|
L
|
L
|
Y
|
V
|
S
|
M
|
I
|
140 |
C
|
V
|
F
|
H
|
S
|
K
|
Y
|
A
|
G
|
F
|
150 |
ECL2 | |||||||||
M
|
V
|
P
|
Y
|
F
|
L
|
R
|
K
|
F
|
F
|
160 |
S
|
Q
|
N
|
A
|
T
|
I
|
Q
|
K
|
E
|
D
|
170 |
TM5 | |||||||||
T
|
L
|
A
|
I
|
Q
|
I
|
F
|
S
|
F
|
V
|
180 |
A
|
E
|
F
|
S
|
V
|
P
|
L
|
L
|
I
|
F
|
190 |
L
|
F
|
A
|
V
|
L
|
L
|
L
|
I
|
F
|
S
|
200 |
L
|
G
|
R
|
H
|
T
|
R
|
Q
|
M
|
R
|
N
|
210 |
ICL3 | TM6 | ||||||||
T
|
V
|
A
|
G
|
S
|
R
|
V
|
P
|
G
|
R
|
220 |
G
|
A
|
P
|
I
|
S
|
A
|
L
|
L
|
S
|
I
|
230 |
L
|
S
|
F
|
L
|
I
|
L
|
Y
|
F
|
S
|
H
|
240 |
C
|
M
|
I
|
K
|
V
|
F
|
L
|
S
|
S
|
L
|
250 |
ECL3 | TM7 | ||||||||
K
|
F
|
H
|
I
|
R
|
R
|
F
|
I
|
F
|
L
|
260 |
F
|
F
|
I
|
L
|
V
|
I
|
G
|
I
|
Y
|
P
|
270 |
S
|
G
|
H
|
S
|
L
|
I
|
L
|
I
|
L
|
G
|
280 |
H8 | |||||||||
N
|
P
|
K
|
L
|
K
|
Q
|
N
|
A
|
K
|
K
|
290 |
F
|
L
|
L
|
H
|
S
|
K
|
C
|
C
|
Q
|
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
No structures available