GPR171 homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Active
VERSION
2021-06-10
MODEL
TEMPLATES
4NTJ (P2Y12 receptor)
4PXZ (P2Y12 receptor)
6LFO (CXCR2)
6RZ4 (CysLT1 receptor)
5XSZ (LPA6 receptor)
6B73 (κ receptor)
None
4PXZ (P2Y12 receptor)
6LFO (CXCR2)
6RZ4 (CysLT1 receptor)
5XSZ (LPA6 receptor)
6B73 (κ receptor)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 81.3 | 11.7 | 7.0 |
| Side-chains | 21.3 | 57.3 | 21.3 |
Number of backbone templates: 6
Number of rotamer templates: 51
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 5 | S | - | P2Y12 receptor | 4NTJ | P2Y12 receptor | 4NTJ |
| N-term | 6 | F | - | P2Y12 receptor | 4NTJ | P2Y12 receptor | 4NTJ |
| N-term | 7 | F | - | P2Y12 receptor | 4NTJ | P2Y12 receptor | 4NTJ |
| N-term | 8 | C | - | P2Y12 receptor | 4NTJ | P2Y12 receptor | 4NTJ |
| N-term | 9 | P | - | P2Y12 receptor | 4NTJ | P2Y12 receptor | 4NTJ |
| TM1 | 10 | V | 1.28x28 | P2Y12 receptor | 4NTJ | BLT1 receptor | 7K15 |
| TM1 | 11 | Y | 1.29x29 | CXCR2 | 6LFO | - | - |
| TM1 | 12 | K | 1.30x30 | CXCR2 | 6LFO | - | - |
| TM1 | 13 | D | 1.31x31 | CXCR2 | 6LFO | - | - |
| TM1 | 14 | L | 1.32x32 | CXCR2 | 6LFO | ghrelin receptor | 6KO5 |
| TM1 | 15 | E | 1.33x33 | CXCR2 | 6LFO | CysLT2 receptor | 6RZ7 |
| TM1 | 16 | P | 1.34x34 | CXCR2 | 6LFO | 5-HT2C receptor | 6BQG |
| TM1 | 17 | F | 1.35x35 | CXCR2 | 6LFO | P2Y12 receptor | 4NTJ |
| TM1 | 18 | T | 1.36x36 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM1 | 19 | Y | 1.37x37 | CXCR2 | 6LFO | - | - |
| TM1 | 20 | F | 1.38x38 | CXCR2 | 6LFO | D1 receptor | 7JVQ |
| TM1 | 21 | F | 1.39x39 | CXCR2 | 6LFO | MC4 receptor | 7AUE |
| TM1 | 22 | Y | 1.40x40 | CXCR2 | 6LFO | AT2 receptor | 5UNG |
| TM1 | 23 | L | 1.41x41 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM1 | 24 | V | 1.42x42 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM1 | 25 | F | 1.43x43 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM1 | 26 | L | 1.44x44 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM1 | 27 | V | 1.45x45 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM1 | 28 | G | 1.46x46 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM1 | 29 | I | 1.47x47 | CXCR2 | 6LFO | AT1 receptor | 6DO1 |
| TM1 | 30 | I | 1.48x48 | CXCR2 | 6LFO | OX2 receptor | 7L1V |
| TM1 | 31 | G | 1.49x49 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM1 | 32 | S | 1.50x50 | CXCR2 | 6LFO | - | - |
| TM1 | 33 | C | 1.51x51 | CXCR2 | 6LFO | NOP receptor | 5DHG |
| TM1 | 34 | F | 1.52x52 | CXCR2 | 6LFO | 5-HT1D receptor | 7E32 |
| TM1 | 35 | A | 1.53x53 | CXCR2 | 6LFO | EP4 receptor | 7D7M |
| TM1 | 36 | T | 1.54x54 | CXCR2 | 6LFO | - | - |
| TM1 | 37 | W | 1.55x55 | CXCR2 | 6LFO | FPR2/ALX | 6OMM |
| TM1 | 38 | A | 1.56x56 | CXCR2 | 6LFO | OX2 receptor | 7L1V |
| TM1 | 39 | F | 1.57x57 | CXCR2 | 6LFO | CCR6 | 6WWZ |
| TM1 | 40 | I | 1.58x58 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM1 | 41 | Q | 1.59x59 | CXCR2 | 6LFO | Rhodopsin | 4X1H |
| TM1 | 42 | K | 1.60x60 | P2Y12 receptor | 4NTJ | NTS1 receptor | 6OSA |
| ICL1 | 43 | N | - | - | - | - | - |
| ICL1 | 44 | T | - | CysLT1 receptor | 6RZ4 | - | - |
| ICL1 | 45 | N | - | CysLT1 receptor | 6RZ4 | - | - |
| ICL1 | 46 | H | - | - | - | - | - |
| TM2 | 47 | R | 2.37x37 | P2Y12 receptor | 4NTJ | CB1 receptor | 6KPG |
| TM2 | 48 | C | 2.38x38 | CXCR2 | 6LFO | - | - |
| TM2 | 49 | V | 2.39x39 | CXCR2 | 6LFO | NTS1 receptor | 4XES |
| TM2 | 50 | S | 2.40x40 | CXCR2 | 6LFO | AT1 receptor | 6DO1 |
| TM2 | 51 | I | 2.41x41 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM2 | 52 | Y | 2.42x42 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM2 | 53 | L | 2.43x43 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM2 | 54 | I | 2.44x44 | CXCR2 | 6LFO | US28 | 5WB1 |
| TM2 | 55 | N | 2.45x45 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM2 | 56 | L | 2.46x46 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM2 | 57 | L | 2.47x47 | CXCR2 | 6LFO | GPBA receptor | 7CFN |
| TM2 | 58 | T | 2.48x48 | CXCR2 | 6LFO | 5-HT1D receptor | 7E32 |
| TM2 | 59 | A | 2.49x49 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM2 | 60 | D | 2.50x50 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM2 | 61 | F | 2.51x51 | CXCR2 | 6LFO | FPR2/ALX | 6OMM |
| TM2 | 62 | L | 2.52x52 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM2 | 63 | L | 2.53x53 | CXCR2 | 6LFO | AT2 receptor | 5UNG |
| TM2 | 64 | T | 2.54x54 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM2 | 65 | L | 2.55x55 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM2 | 66 | A | 2.56x56 | CXCR2 | 6LFO | NTS1 receptor | 4XES |
| TM2 | 67 | L | 2.57x57 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM2 | 68 | P | 2.58x58 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM2 | 69 | V | 2.59x59 | CXCR2 | 6LFO | NTS1 receptor | 4XES |
| TM2 | 70 | K | 2.60x60 | CXCR2 | 6LFO | D1 receptor | 7JVQ |
| TM2 | 71 | I | 2.61x61 | CXCR2 | 6LFO | FPR2/ALX | 6OMM |
| TM2 | 72 | V | 2.62x62 | CXCR2 | 6LFO | OX2 receptor | 7L1V |
| TM2 | 73 | V | 2.63x63 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM2 | 74 | D | 2.64x64 | CXCR2 | 6LFO | OX2 receptor | 7L1V |
| TM2 | 75 | L | 2.65x65 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM2 | 76 | G | 2.66x66 | CXCR2 | 6LFO | A1 receptor | 6D9H |
| ECL1 | 77 | V | - | - | - | - | - |
| ECL1 | 78 | A | - | P2Y12 receptor | 4PXZ | - | - |
| ECL1 | 79 | P | - | - | - | - | - |
| TM3 | 80 | W | 3.18x18 | P2Y12 receptor | 4PXZ | - | - |
| TM3 | 81 | K | 3.19x19 | P2Y12 receptor | 4PXZ | - | - |
| TM3 | 82 | L | 3.20x20 | P2Y12 receptor | 4PXZ | P2Y12 receptor | 4PXZ |
| TM3 | 83 | K | 3.21x21 | P2Y12 receptor | 4PXZ | - | - |
| TM3 | 84 | I | 3.22x22 | CXCR2 | 6LFO | - | - |
| TM3 | 85 | F | 3.23x23 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 86 | H | 3.24x24 | CXCR2 | 6LFO | D2 receptor | 7JVR |
| TM3 | 87 | C | 3.25x25 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 88 | Q | 3.26x26 | CXCR2 | 6LFO | GPR52 | 6LI3 |
| TM3 | 89 | V | 3.27x27 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 90 | T | 3.28x28 | CXCR2 | 6LFO | CCK1 receptor | 7MBX |
| TM3 | 91 | A | 3.29x29 | CXCR2 | 6LFO | A1 receptor | 6D9H |
| TM3 | 92 | C | 3.30x30 | CXCR2 | 6LFO | A1 receptor | 6D9H |
| TM3 | 93 | L | 3.31x31 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 94 | I | 3.32x32 | CXCR2 | 6LFO | MC4 receptor | 7AUE |
| TM3 | 95 | Y | 3.33x33 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM3 | 96 | I | 3.34x34 | CXCR2 | 6LFO | CCR6 | 6WWZ |
| TM3 | 97 | N | 3.35x35 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 98 | M | 3.36x36 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM3 | 99 | Y | 3.37x37 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 100 | L | 3.38x38 | CXCR2 | 6LFO | - | - |
| TM3 | 101 | S | 3.39x39 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM3 | 102 | I | 3.40x40 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 103 | I | 3.41x41 | CXCR2 | 6LFO | Y2 receptor | 7DDZ |
| TM3 | 104 | F | 3.42x42 | CXCR2 | 6LFO | US28 | 5WB1 |
| TM3 | 105 | L | 3.43x43 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 106 | A | 3.44x44 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 107 | F | 3.45x45 | CXCR2 | 6LFO | FPR2/ALX | 6OMM |
| TM3 | 108 | V | 3.46x46 | CXCR2 | 6LFO | GPBA receptor | 7CFN |
| TM3 | 109 | S | 3.47x47 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 110 | I | 3.48x48 | CXCR2 | 6LFO | AT1 receptor | 6DO1 |
| TM3 | 111 | D | 3.49x49 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 112 | R | 3.50x50 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 113 | C | 3.51x51 | CXCR2 | 6LFO | FPR2/ALX | 6OMM |
| TM3 | 114 | L | 3.52x52 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM3 | 115 | Q | 3.53x53 | CXCR2 | 6LFO | DP2 receptor | 6D27 |
| TM3 | 116 | L | 3.54x54 | CXCR2 | 6LFO | CB2 receptor | 6PT0 |
| TM3 | 117 | T | 3.55x55 | CXCR2 | 6LFO | β1-adrenoceptor | 7BU7 |
| TM3 | 118 | H | 3.56x56 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| ICL2 | 119 | S | 34.50x50 | - | - | - | - |
| ICL2 | 120 | C | 34.51x51 | LPA6 receptor | 5XSZ | - | - |
| ICL2 | 121 | K | 34.52x52 | LPA6 receptor | 5XSZ | κ receptor | 6B73 |
| ICL2 | 122 | I | 34.53x53 | LPA6 receptor | 5XSZ | - | - |
| ICL2 | 123 | Y | 34.54x54 | LPA6 receptor | 5XSZ | - | - |
| ICL2 | 124 | R | 34.55x55 | LPA6 receptor | 5XSZ | CCR6 | 6WWZ |
| ICL2 | 125 | I | 34.56x56 | LPA6 receptor | 5XSZ | MC4 receptor | 7AUE |
| ICL2 | 126 | Q | 34.57x57 | - | - | - | - |
| TM4 | 127 | E | 4.38x38 | P2Y12 receptor | 4NTJ | - | - |
| TM4 | 128 | P | 4.39x39 | P2Y12 receptor | 4NTJ | κ receptor | 6B73 |
| TM4 | 129 | G | 4.40x40 | P2Y12 receptor | 4NTJ | 5-HT1D receptor | 7E32 |
| TM4 | 130 | F | 4.41x41 | CXCR2 | 6LFO | succinate receptor | 6RNK |
| TM4 | 131 | A | 4.42x42 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM4 | 132 | K | 4.43x43 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM4 | 133 | M | 4.44x44 | CXCR2 | 6LFO | 5-HT2C receptor | 6BQG |
| TM4 | 134 | I | 4.45x45 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM4 | 135 | S | 4.46x46 | CXCR2 | 6LFO | US28 | 5WB1 |
| TM4 | 136 | T | 4.47x47 | CXCR2 | 6LFO | 5-HT2B receptor | 5TUD |
| TM4 | 137 | V | 4.48x48 | CXCR2 | 6LFO | CCR6 | 6WWZ |
| TM4 | 138 | V | 4.49x49 | CXCR2 | 6LFO | CCR6 | 6WWZ |
| TM4 | 139 | W | 4.50x50 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM4 | 140 | L | 4.51x51 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM4 | 141 | M | 4.52x52 | CXCR2 | 6LFO | AT2 receptor | 5UNG |
| TM4 | 142 | V | 4.53x53 | CXCR2 | 6LFO | EP3 receptor | 6M9T |
| TM4 | 143 | L | 4.54x54 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM4 | 144 | L | 4.55x55 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM4 | 145 | I | 4.56x56 | CXCR2 | 6LFO | OX2 receptor | 7L1V |
| TM4 | 146 | M | 4.57x57 | CXCR2 | 6LFO | OX2 receptor | 7L1V |
| TM4 | 147 | V | 4.58x59 | CXCR2 | 6LFO | 5-HT2C receptor | 6BQG |
| TM4 | 148 | P | 4.59x60 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM4 | 149 | N | 4.60x61 | CXCR2 | 6LFO | EP4 receptor | 7D7M |
| TM4 | 150 | M | 4.61x62 | CXCR2 | 6LFO | CB2 receptor | 6PT0 |
| TM4 | 151 | M | 4.62x63 | CXCR2 | 6LFO | μ receptor | 5C1M |
| TM4 | 152 | I | 4.63x64 | LPA6 receptor | 5XSZ | 5-HT2C receptor | 6BQG |
| TM4 | 153 | P | 4.64x65 | LPA6 receptor | 5XSZ | - | - |
| ECL2 | 154 | I | - | CXCR2 | 6LFO | - | - |
| ECL2 | 155 | K | - | CXCR2 | 6LFO | - | - |
| ECL2 | 156 | D | - | CXCR2 | 6LFO | - | - |
| ECL2 | 157 | I | - | CXCR2 | 6LFO | - | - |
| ECL2 | 158 | K | - | CXCR2 | 6LFO | - | - |
| ECL2 | 159 | E | - | CXCR2 | 6LFO | - | - |
| ECL2 | 160 | K | - | CXCR2 | 6LFO | - | - |
| ECL2 | 161 | S | - | CXCR2 | 6LFO | - | - |
| ECL2 | 162 | N | - | CXCR2 | 6LFO | - | - |
| ECL2 | 163 | V | - | CXCR2 | 6LFO | - | - |
| ECL2 | 164 | G | - | CXCR2 | 6LFO | - | - |
| ECL2 | 165 | C | 45.50x50 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| ECL2 | 166 | M | 45.51x51 | CXCR2 | 6LFO | δ receptor | 6PT2 |
| ECL2 | 167 | E | 45.52x52 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| ECL2 | 168 | F | - | - | - | - | - |
| ECL2 | 169 | K | - | - | - | - | - |
| ECL2 | 170 | K | - | - | - | - | - |
| TM5 | 171 | E | 5.30x30 | P2Y12 receptor | 4NTJ | P2Y12 receptor | 4NTJ |
| TM5 | 172 | F | 5.31x31 | CXCR2 | 6LFO | P2Y12 receptor | 4NTJ |
| TM5 | 173 | G | 5.32x32 | CXCR2 | 6LFO | P2Y12 receptor | 4NTJ |
| TM5 | 174 | R | 5.33x33 | CXCR2 | 6LFO | - | - |
| TM5 | 175 | N | 5.34x34 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM5 | 176 | W | 5.35x35 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM5 | 177 | H | 5.36x36 | CXCR2 | 6LFO | EP4 receptor | 7D7M |
| TM5 | 178 | L | 5.37x37 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM5 | 179 | L | 5.38x38 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM5 | 180 | T | 5.39x39 | CXCR2 | 6LFO | δ receptor | 6PT2 |
| TM5 | 181 | N | 5.40x40 | CXCR2 | 6LFO | US28 | 5WB1 |
| TM5 | 182 | F | 5.41x41 | CXCR2 | 6LFO | M1 receptor | 6OIJ |
| TM5 | 183 | I | 5.42x42 | CXCR2 | 6LFO | FPR2/ALX | 6OMM |
| TM5 | 184 | C | 5.43x43 | CXCR2 | 6LFO | P2Y12 receptor | 4NTJ |
| TM5 | 185 | V | 5.44x44 | CXCR2 | 6LFO | GPBA receptor | 7CFN |
| TM5 | 186 | A | 5.45x45 | CXCR2 | 6LFO | - | - |
| TM5 | 187 | I | 5.46x46 | P2Y12 receptor | 4NTJ | P2Y12 receptor | 4NTJ |
| TM5 | 188 | F | 5.47x47 | P2Y12 receptor | 4NTJ | P2Y12 receptor | 4NTJ |
| TM5 | 189 | L | 5.48x48 | CXCR2 | 6LFO | AT1 receptor | 6DO1 |
| TM5 | 190 | N | 5.49x49 | CXCR2 | 6LFO | - | - |
| TM5 | 191 | F | 5.50x50 | CXCR2 | 6LFO | - | - |
| TM5 | 192 | S | 5.51x51 | CXCR2 | 6LFO | 5-HT1D receptor | 7E32 |
| TM5 | 193 | A | 5.52x52 | CXCR2 | 6LFO | 5-HT2B receptor | 5TUD |
| TM5 | 194 | I | 5.53x53 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM5 | 195 | I | 5.54x54 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM5 | 196 | L | 5.55x55 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM5 | 197 | I | 5.56x56 | CXCR2 | 6LFO | FPR2/ALX | 6OMM |
| TM5 | 198 | S | 5.57x57 | CXCR2 | 6LFO | AT1 receptor | 6DO1 |
| TM5 | 199 | N | 5.58x58 | CXCR2 | 6LFO | NTS1 receptor | 4XES |
| TM5 | 200 | C | 5.59x59 | CXCR2 | 6LFO | 5-HT2C receptor | 6BQG |
| TM5 | 201 | L | 5.60x60 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM5 | 202 | V | 5.61x61 | CXCR2 | 6LFO | β1-adrenoceptor | 7BU7 |
| TM5 | 203 | I | 5.62x62 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM5 | 204 | R | 5.63x63 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM5 | 205 | Q | 5.64x64 | CXCR2 | 6LFO | Rhodopsin | 6I9K |
| TM5 | 206 | L | 5.65x65 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM5 | 207 | Y | 5.66x66 | CXCR2 | 6LFO | CCK1 receptor | 7MBX |
| TM5 | 208 | R | 5.67x67 | CXCR2 | 6LFO | 5-HT2C receptor | 6BQG |
| ICL3 | 209 | N | - | - | - | - | - |
| ICL3 | 210 | K | - | - | - | - | - |
| ICL3 | 211 | D | - | - | - | - | - |
| ICL3 | 212 | N | - | - | - | - | - |
| ICL3 | 213 | E | - | - | - | - | - |
| TM6 | 214 | N | 6.26x26 | κ receptor | 6B73 | AT2 receptor | 5UNG |
| TM6 | 215 | Y | 6.27x27 | κ receptor | 6B73 | A1 receptor | 6D9H |
| TM6 | 216 | P | 6.28x28 | κ receptor | 6B73 | - | - |
| TM6 | 217 | N | 6.29x29 | CXCR2 | 6LFO | μ receptor | 5C1M |
| TM6 | 218 | V | 6.30x30 | CXCR2 | 6LFO | V2 receptor | 7KH0 |
| TM6 | 219 | K | 6.31x31 | CXCR2 | 6LFO | CCK1 receptor | 7MBX |
| TM6 | 220 | K | 6.32x32 | CXCR2 | 6LFO | OX2 receptor | 7L1V |
| TM6 | 221 | A | 6.33x33 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM6 | 222 | L | 6.34x34 | CXCR2 | 6LFO | FPR2/ALX | 6OMM |
| TM6 | 223 | I | 6.35x35 | CXCR2 | 6LFO | MC4 receptor | 7AUE |
| TM6 | 224 | N | 6.36x36 | CXCR2 | 6LFO | - | - |
| TM6 | 225 | I | 6.37x37 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM6 | 226 | L | 6.38x38 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM6 | 227 | L | 6.39x39 | CXCR2 | 6LFO | 5-ht1E receptor | 7E33 |
| TM6 | 228 | V | 6.40x40 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM6 | 229 | T | 6.41x41 | CXCR2 | 6LFO | GPR52 | 6LI3 |
| TM6 | 230 | T | 6.42x42 | CXCR2 | 6LFO | CysLT1 receptor | 6RZ4 |
| TM6 | 231 | G | 6.43x43 | CXCR2 | 6LFO | - | - |
| TM6 | 232 | Y | 6.44x44 | CXCR2 | 6LFO | V2 receptor | 7KH0 |
| TM6 | 233 | I | 6.45x45 | CXCR2 | 6LFO | μ receptor | 5C1M |
| TM6 | 234 | I | 6.46x46 | CXCR2 | 6LFO | OX2 receptor | 7L1V |
| TM6 | 235 | C | 6.47x47 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM6 | 236 | F | 6.48x48 | CXCR2 | 6LFO | P2Y12 receptor | 4NTJ |
| TM6 | 237 | V | 6.49x49 | CXCR2 | 6LFO | Rhodopsin | 5W0P |
| TM6 | 238 | P | 6.50x50 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM6 | 239 | Y | 6.51x51 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM6 | 240 | H | 6.52x52 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM6 | 241 | I | 6.53x53 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM6 | 242 | V | 6.54x54 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM6 | 243 | R | 6.55x55 | CXCR2 | 6LFO | NTS1 receptor | 4XES |
| TM6 | 244 | I | 6.56x56 | CXCR2 | 6LFO | μ receptor | 5C1M |
| TM6 | 245 | P | 6.57x57 | CXCR2 | 6LFO | P2Y12 receptor | 4NTJ |
| TM6 | 246 | Y | 6.58x58 | CXCR2 | 6LFO | MC4 receptor | 7AUE |
| TM6 | 247 | T | 6.59x59 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM6 | 248 | L | 6.60x60 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM6 | 249 | S | 6.61x61 | CXCR2 | 6LFO | 5-ht1E receptor | 7E33 |
| TM6 | 250 | Q | 6.62x62 | CXCR2 | 6LFO | AT1 receptor | 6OS2 |
| TM6 | 251 | T | 6.63x63 | P2Y12 receptor | 4PXZ | P2Y12 receptor | 4PXZ |
| TM6 | 252 | E | 6.64x64 | P2Y12 receptor | 4PXZ | - | - |
| ECL3 | 253 | V | - | - | - | - | - |
| ECL3 | 254 | I | - | P2Y12 receptor | 4PXZ | - | - |
| ECL3 | 255 | T | - | - | - | - | - |
| TM7 | 256 | D | 7.24x23 | CXCR2 | 6LFO | AT1 receptor | 6DO1 |
| TM7 | 257 | C | 7.25x24 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM7 | 258 | S | 7.26x25 | CXCR2 | 6LFO | CCR5 | 4MBS |
| TM7 | 259 | T | 7.27x26 | CXCR2 | 6LFO | C5a1 receptor | 6C1Q |
| TM7 | 260 | R | 7.28x27 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM7 | 261 | I | 7.29x28 | CXCR2 | 6LFO | - | - |
| TM7 | 262 | S | 7.30x29 | CXCR2 | 6LFO | US28 | 5WB1 |
| TM7 | 263 | L | 7.31x30 | CXCR2 | 6LFO | US28 | 5WB1 |
| TM7 | 264 | F | 7.32x31 | CXCR2 | 6LFO | P2Y12 receptor | 4NTJ |
| TM7 | 265 | K | 7.33x32 | CXCR2 | 6LFO | CB2 receptor | 6PT0 |
| TM7 | 266 | A | 7.34x33 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM7 | 267 | K | 7.35x34 | CXCR2 | 6LFO | CCR6 | 6WWZ |
| TM7 | 268 | E | 7.36x35 | CXCR2 | 6LFO | 5-HT2B receptor | 5TUD |
| TM7 | 269 | A | 7.37x36 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM7 | 270 | T | 7.38x37 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM7 | 271 | L | 7.39x38 | CXCR2 | 6LFO | CCK1 receptor | 7MBX |
| TM7 | 272 | L | 7.40x39 | CXCR2 | 6LFO | AT2 receptor | 5UNG |
| TM7 | 273 | L | 7.41x40 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM7 | 274 | A | 7.42x41 | CXCR2 | 6LFO | CCR6 | 6WWZ |
| TM7 | 275 | V | 7.43x42 | CXCR2 | 6LFO | LPA6 receptor | 5XSZ |
| TM7 | 276 | S | 7.44x43 | CXCR2 | 6LFO | GPR52 | 6LI3 |
| TM7 | 277 | N | 7.45x45 | CXCR2 | 6LFO | κ receptor | 6B73 |
| TM7 | 278 | L | 7.46x46 | CXCR2 | 6LFO | - | - |
| TM7 | 279 | C | 7.47x47 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM7 | 280 | F | 7.48x48 | CXCR2 | 6LFO | β1-adrenoceptor | 7BU7 |
| TM7 | 281 | D | 7.49x49 | CXCR2 | 6LFO | MC4 receptor | 7AUE |
| TM7 | 282 | P | 7.50x50 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM7 | 283 | I | 7.51x51 | CXCR2 | 6LFO | OX2 receptor | 7L1V |
| TM7 | 284 | L | 7.52x52 | CXCR2 | 6LFO | CCR6 | 6WWZ |
| TM7 | 285 | Y | 7.53x53 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| TM7 | 286 | Y | 7.54x54 | CXCR2 | 6LFO | LPA6 receptor | 5XSZ |
| TM7 | 287 | H | 7.55x55 | CXCR2 | 6LFO | - | - |
| TM7 | 288 | L | 7.56x56 | CXCR2 | 6LFO | OX2 receptor | 7L1V |
| H8 | 289 | S | 8.47x47 | CXCR2 | 6LFO | OX2 receptor | 7L1V |
| H8 | 290 | K | 8.48x48 | CXCR2 | 6LFO | δ receptor | 6PT2 |
| H8 | 291 | A | 8.49x49 | CXCR2 | 6LFO | M1 receptor | 6OIJ |
| H8 | 292 | F | 8.50x50 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| H8 | 293 | R | 8.51x51 | CXCR2 | 6LFO | CXCR2 | 6LFO |
| H8 | 294 | S | 8.52x52 | CXCR2 | 6LFO | 5-HT2A receptor | 6WHA |
| H8 | 295 | K | 8.53x53 | CXCR2 | 6LFO | AT2 receptor | 5UNG |
| H8 | 296 | V | 8.54x54 | CXCR2 | 6LFO | ghrelin receptor | 6KO5 |
| H8 | 297 | T | 8.55x55 | CXCR2 | 6LFO | apelin receptor | 5VBL |
| H8 | 298 | E | 8.56x56 | CXCR2 | 6LFO | β2-adrenoceptor | 3SN6 |
| H8 | 299 | T | 8.57x57 | CXCR2 | 6LFO | NTS1 receptor | 7L0P |
| C-term | 300 | F | - | - | - | - | - |
| C-term | 301 | A | - | - | - | - | - |
| C-term | 302 | S | - | - | - | - | - |
| C-term | 303 | P | - | - | - | - | - |
| C-term | 304 | K | - | - | - | - | - |