LPA6 receptor homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Inactive
VERSION
2021-06-10
MODEL
TEMPLATES
6RZ4 (CysLT1 receptor)
4MBS (CCR5)
6MEO (CCR5)
4ZUD (AT1 receptor)
5XSZ (LPA6 receptor)
6B73 (κ receptor)
None
4MBS (CCR5)
6MEO (CCR5)
4ZUD (AT1 receptor)
5XSZ (LPA6 receptor)
6B73 (κ receptor)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 80.4 | 8.7 | 10.9 |
| Side-chains | 22.1 | 59.3 | 18.6 |
Number of backbone templates: 6
Number of rotamer templates: 52
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 1 | M | - | - | - | - | - |
| N-term | 2 | V | - | - | - | - | - |
| N-term | 3 | S | - | - | - | - | - |
| N-term | 4 | V | - | - | - | - | - |
| TM1 | 5 | N | 1.20x20 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 6 | S | 1.21x21 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 7 | S | 1.22x22 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 8 | H | 1.23x23 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 9 | C | 1.24x24 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 10 | F | 1.25x25 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 11 | Y | 1.26x26 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 12 | N | 1.27x27 | CCR5 | 4MBS | CXCR4 | 4RWS |
| TM1 | 13 | D | 1.28x28 | CCR5 | 4MBS | β2-adrenoceptor | 5JQH |
| TM1 | 14 | S | 1.29x29 | CCR5 | 4MBS | MT1 receptor | 6ME3 |
| TM1 | 15 | F | 1.30x30 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM1 | 16 | K | 1.31x31 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM1 | 17 | Y | 1.32x32 | CCR5 | 4MBS | PAF receptor | 5ZKQ |
| TM1 | 18 | T | 1.33x33 | CCR5 | 4MBS | CB2 receptor | 5ZTY |
| TM1 | 19 | L | 1.34x34 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 20 | Y | 1.35x35 | CCR5 | 4MBS | D2 receptor | 6CM4 |
| TM1 | 21 | G | 1.36x36 | CCR5 | 4MBS | β2-adrenoceptor | 2RH1 |
| TM1 | 22 | C | 1.37x37 | CCR5 | 4MBS | MT1 receptor | 6ME2 |
| TM1 | 23 | M | 1.38x38 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM1 | 24 | F | 1.39x39 | CCR5 | 4MBS | C5a1 receptor | 6C1Q |
| TM1 | 25 | S | 1.40x40 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 26 | M | 1.41x41 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| TM1 | 27 | V | 1.42x42 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 28 | F | 1.43x43 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 29 | V | 1.44x44 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM1 | 30 | L | 1.45x45 | CCR5 | 4MBS | CXCR2 | 6LFL |
| TM1 | 31 | G | 1.46x46 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 32 | L | 1.47x47 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM1 | 33 | I | 1.48x48 | CCR5 | 4MBS | ETB receptor | 5X93 |
| TM1 | 34 | S | 1.49x49 | CCR5 | 4MBS | 5-HT1B receptor | 4IAQ |
| TM1 | 35 | N | 1.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 36 | C | 1.51x51 | CCR5 | 4MBS | NOP receptor | 5DHG |
| TM1 | 37 | V | 1.52x52 | CCR5 | 4MBS | NK1 receptor | 6HLP |
| TM1 | 38 | A | 1.53x53 | CCR5 | 4MBS | EP4 receptor | 5YWY |
| TM1 | 39 | I | 1.54x54 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 40 | Y | 1.55x55 | CCR5 | 4MBS | μ receptor | 4DKL |
| TM1 | 41 | I | 1.56x56 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 42 | F | 1.57x57 | CCR5 | 4MBS | M1 receptor | 6WJC |
| TM1 | 43 | I | 1.58x58 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 44 | C | 1.59x59 | CCR5 | 4MBS | DP2 receptor | 6D27 |
| TM1 | 45 | V | 1.60x60 | CCR5 | 4MBS | - | - |
| ICL1 | 46 | L | 12.48x48 | - | - | - | - |
| ICL1 | 47 | K | 12.49x49 | AT1 receptor | 4ZUD | AT1 receptor | 4YAY |
| ICL1 | 48 | V | 12.50x50 | AT1 receptor | 4ZUD | - | - |
| ICL1 | 49 | R | 12.51x51 | - | - | - | - |
| TM2 | 50 | N | 2.37x37 | CCR5 | 4MBS | ETB receptor | 6IGK |
| TM2 | 51 | E | 2.38x38 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 52 | T | 2.39x39 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 53 | T | 2.40x40 | CCR5 | 4MBS | DP2 receptor | 6D27 |
| TM2 | 54 | T | 2.41x41 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM2 | 55 | Y | 2.42x42 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 56 | M | 2.43x43 | CCR5 | 4MBS | OT receptor | 6TPK |
| TM2 | 57 | I | 2.44x44 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| TM2 | 58 | N | 2.45x45 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 59 | L | 2.46x46 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 60 | A | 2.47x47 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 61 | M | 2.48x48 | CCR5 | 4MBS | PAF receptor | 5ZKQ |
| TM2 | 62 | S | 2.49x49 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 63 | D | 2.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 64 | L | 2.51x51 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 65 | L | 2.52x52 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM2 | 66 | F | 2.53x53 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 67 | V | 2.54x54 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM2 | 68 | F | 2.55x55 | CCR5 | 4MBS | Rhodopsin | 1U19 |
| TM2 | 69 | T | 2.56x56 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 70 | L | 2.57x57 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM2 | 71 | P | 2.58x58 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 72 | F | 2.59x59 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 73 | R | 2.60x60 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 74 | I | 2.61x61 | CCR5 | 4MBS | H1 receptor | 3RZE |
| TM2 | 75 | F | 2.62x62 | CCR5 | 4MBS | NK1 receptor | 6HLP |
| TM2 | 76 | Y | 2.63x63 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 77 | F | 2.64x64 | CCR5 | 4MBS | NTS1 receptor | 4BUO |
| TM2 | 78 | T | 2.65x65 | CCR5 | 4MBS | BLT1 receptor | 5X33 |
| TM2 | 79 | T | 2.66x66 | CCR5 | 4MBS | OX2 receptor | 6TPN |
| ECL1 | 80 | R | - | - | - | - | - |
| ECL1 | 81 | N | 23.49x49 | LPA6 receptor | 5XSZ | LPA6 receptor | 5XSZ |
| ECL1 | 82 | W | 23.50x50 | LPA6 receptor | 5XSZ | LPA6 receptor | 5XSZ |
| ECL1 | 83 | P | 23.51x51 | LPA6 receptor | 5XSZ | LPA6 receptor | 5XSZ |
| ECL1 | 84 | F | 23.52x52 | - | - | - | - |
| TM3 | 85 | G | 3.21x21 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 86 | D | 3.22x22 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM3 | 87 | L | 3.23x23 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM3 | 88 | L | 3.24x24 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 89 | C | 3.25x25 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 90 | K | 3.26x26 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 91 | I | 3.27x27 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 92 | S | 3.28x28 | CCR5 | 4MBS | apelin receptor | 5VBL |
| TM3 | 93 | V | 3.29x29 | CCR5 | 4MBS | D3 receptor | 3PBL |
| TM3 | 94 | M | 3.30x30 | CCR5 | 4MBS | Rhodopsin | 6I9K |
| TM3 | 95 | L | 3.31x31 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 96 | F | 3.32x32 | CCR5 | 4MBS | DP2 receptor | 6D27 |
| TM3 | 97 | Y | 3.33x33 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM3 | 98 | T | 3.34x34 | CCR5 | 4MBS | 5-HT1B receptor | 4IAQ |
| TM3 | 99 | N | 3.35x35 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 100 | M | 3.36x36 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM3 | 101 | Y | 3.37x37 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 102 | G | 3.38x38 | CCR5 | 4MBS | CCR2 | 5T1A |
| TM3 | 103 | S | 3.39x39 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 104 | I | 3.40x40 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 105 | L | 3.41x41 | CCR5 | 4MBS | CCR9 | 5LWE |
| TM3 | 106 | F | 3.42x42 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 107 | L | 3.43x43 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 108 | T | 3.44x44 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 109 | C | 3.45x45 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 110 | I | 3.46x46 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM3 | 111 | S | 3.47x47 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 112 | V | 3.48x48 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM3 | 113 | D | 3.49x49 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 114 | R | 3.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 115 | F | 3.51x51 | CCR5 | 4MBS | C5a1 receptor | 6C1Q |
| TM3 | 116 | L | 3.52x52 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 117 | A | 3.53x53 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 118 | I | 3.54x54 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM3 | 119 | V | 3.55x55 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 120 | Y | 3.56x56 | CCR5 | 4MBS | Y2 receptor | 7DDZ |
| ICL2 | 121 | P | 34.50x50 | - | - | - | - |
| ICL2 | 122 | F | 34.51x51 | LPA6 receptor | 5XSZ | LPA6 receptor | 5XSZ |
| ICL2 | 123 | K | 34.52x52 | LPA6 receptor | 5XSZ | μ receptor | 4DKL |
| ICL2 | 124 | S | 34.53x53 | LPA6 receptor | 5XSZ | LPA6 receptor | 5XSZ |
| ICL2 | 125 | K | 34.54x54 | LPA6 receptor | 5XSZ | ghrelin receptor | 6KO5 |
| ICL2 | 126 | T | 34.55x55 | LPA6 receptor | 5XSZ | CCR9 | 5LWE |
| ICL2 | 127 | L | 34.56x56 | LPA6 receptor | 5XSZ | LPA6 receptor | 5XSZ |
| ICL2 | 128 | R | 34.57x57 | - | - | - | - |
| TM4 | 129 | T | 4.38x38 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM4 | 130 | K | 4.39x39 | CCR5 | 4MBS | BLT1 receptor | 7K15 |
| TM4 | 131 | R | 4.40x40 | CCR5 | 4MBS | μ receptor | 4DKL |
| TM4 | 132 | N | 4.41x41 | CCR5 | 4MBS | μ receptor | 4DKL |
| TM4 | 133 | A | 4.42x42 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM4 | 134 | K | 4.43x43 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM4 | 135 | I | 4.44x44 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM4 | 136 | V | 4.45x45 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM4 | 137 | C | 4.46x46 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM4 | 138 | T | 4.47x47 | CCR5 | 4MBS | D3 receptor | 3PBL |
| TM4 | 139 | G | 4.48x48 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM4 | 140 | V | 4.49x49 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM4 | 141 | W | 4.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM4 | 142 | L | 4.51x51 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM4 | 143 | T | 4.52x52 | CCR5 | 4MBS | - | - |
| TM4 | 144 | V | 4.53x53 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM4 | 145 | I | 4.54x54 | CCR5 | 4MBS | 5-HT2C receptor | 6BQH |
| TM4 | 146 | G | 4.55x55 | CCR5 | 4MBS | δ receptor | 4N6H |
| TM4 | 147 | G | 4.56x56 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM4 | 148 | S | 4.57x57 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM4 | 149 | A | 4.58x59 | CCR5 | 4MBS | Rhodopsin | 6I9K |
| TM4 | 150 | P | 4.59x60 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM4 | 151 | A | 4.60x61 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM4 | 152 | V | 4.61x62 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM4 | 153 | F | 4.62x63 | CCR5 | 4MBS | NTS1 receptor | 4BUO |
| TM4 | 154 | V | 4.63x64 | CCR5 | 4MBS | OX2 receptor | 5WQC |
| ECL2 | 155 | Q | - | - | - | - | - |
| ECL2 | 156 | S | - | - | - | - | - |
| ECL2 | 157 | T | - | - | - | - | - |
| ECL2 | 158 | H | - | - | - | - | - |
| ECL2 | 159 | S | - | - | - | - | - |
| ECL2 | 160 | Q | - | - | - | - | - |
| ECL2 | 161 | G | - | - | - | - | - |
| ECL2 | 162 | N | - | - | - | - | - |
| ECL2 | 163 | N | - | - | - | - | - |
| ECL2 | 164 | A | - | - | - | - | - |
| ECL2 | 165 | S | - | - | - | - | - |
| ECL2 | 166 | E | - | - | - | - | - |
| ECL2 | 167 | A | - | - | - | - | - |
| ECL2 | 168 | C | 45.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| ECL2 | 169 | F | 45.51x51 | CCR5 | 4MBS | BLT1 receptor | 7K15 |
| ECL2 | 170 | E | 45.52x52 | CCR5 | 4MBS | CXCR2 | 6LFL |
| ECL2 | 171 | N | - | - | - | - | - |
| ECL2 | 172 | F | - | CysLT1 receptor | 6RZ4 | - | - |
| ECL2 | 173 | P | - | - | - | - | - |
| TM5 | 174 | E | 5.28x29 | CysLT1 receptor | 6RZ4 | - | - |
| TM5 | 175 | A | 5.29x30 | CysLT1 receptor | 6RZ4 | ETB receptor | 5X93 |
| TM5 | 176 | T | 5.30x31 | CCR5 | 4MBS | DP2 receptor | 6D27 |
| TM5 | 177 | W | 5.31x32 | CCR5 | 4MBS | - | - |
| TM5 | 178 | K | 5.32x33 | CCR5 | 4MBS | NK1 receptor | 6HLP |
| TM5 | 179 | T | 5.33x34 | CCR5 | 4MBS | EP4 receptor | 5YWY |
| TM5 | 180 | Y | 5.34x35 | CCR5 | 4MBS | ETB receptor | 5X93 |
| TM5 | 181 | L | 5.35x36 | CCR5 | 4MBS | ghrelin receptor | 6KO5 |
| TM5 | 182 | S | 5.36x37 | CCR5 | 4MBS | MT1 receptor | 6ME2 |
| TM5 | 183 | R | 5.37x38 | CCR5 | 4MBS | - | - |
| TM5 | 184 | I | 5.38x39 | CCR5 | 4MBS | CCR7 | 6QZH |
| TM5 | 185 | V | 5.39x40 | CCR5 | 4MBS | ghrelin receptor | 6KO5 |
| TM5 | 186 | I | 5.40x41 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM5 | 187 | F | 5.41x42 | CCR5 | 4MBS | BLT1 receptor | 7K15 |
| TM5 | 188 | I | 5.42x43 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 189 | E | 5.43x44 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 190 | I | 5.44x45 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 191 | V | 5.45x46 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM5 | 192 | G | 5.46x461 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 193 | F | 5.47x47 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM5 | 194 | F | 5.48x48 | CCR5 | 4MBS | NK1 receptor | 6HLP |
| TM5 | 195 | I | 5.49x49 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM5 | 196 | P | 5.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 197 | L | 5.51x51 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 198 | I | 5.52x52 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM5 | 199 | L | 5.53x53 | CCR5 | 4MBS | OX2 receptor | 5WQC |
| TM5 | 200 | N | 5.54x54 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 201 | V | 5.55x55 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 202 | T | 5.56x56 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM5 | 203 | C | 5.57x57 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 204 | S | 5.58x58 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 205 | S | 5.59x59 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 206 | M | 5.60x60 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 207 | V | 5.61x61 | CCR5 | 4MBS | NK1 receptor | 6HLP |
| TM5 | 208 | L | 5.62x62 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 209 | K | 5.63x63 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 210 | T | 5.64x64 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 211 | L | 5.65x65 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 212 | T | 5.66x66 | CCR5 | 4MBS | NTS1 receptor | 4BUO |
| TM5 | 213 | K | 5.67x67 | CCR5 | 4MBS | CXCR2 | 6LFL |
| TM5 | 214 | P | 5.68x68 | CCR5 | 6MEO | - | - |
| ICL3 | 215 | V | - | - | - | - | - |
| ICL3 | 216 | T | - | - | - | - | - |
| ICL3 | 217 | L | - | CCR5 | 4MBS | - | - |
| TM6 | 218 | S | 6.24x24 | κ receptor | 6B73 | - | - |
| TM6 | 219 | R | 6.25x25 | κ receptor | 6B73 | LPA1 receptor | 4Z35 |
| TM6 | 220 | S | 6.26x26 | κ receptor | 6B73 | 5-HT2A receptor | 6A94 |
| TM6 | 221 | K | 6.27x27 | κ receptor | 6B73 | - | - |
| TM6 | 222 | I | 6.28x28 | CCR5 | 4MBS | - | - |
| TM6 | 223 | N | 6.29x29 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM6 | 224 | K | 6.30x30 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM6 | 225 | T | 6.31x31 | CCR5 | 4MBS | C5a1 receptor | 6C1Q |
| TM6 | 226 | K | 6.32x32 | CCR5 | 4MBS | CCR2 | 5T1A |
| TM6 | 227 | V | 6.33x33 | CCR5 | 4MBS | ETB receptor | 5X93 |
| TM6 | 228 | L | 6.34x34 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM6 | 229 | K | 6.35x35 | CCR5 | 4MBS | AT1 receptor | 4YAY |
| TM6 | 230 | M | 6.36x36 | CCR5 | 4MBS | μ receptor | 4DKL |
| TM6 | 231 | I | 6.37x37 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 232 | F | 6.38x38 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 233 | V | 6.39x39 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM6 | 234 | H | 6.40x40 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 235 | L | 6.41x41 | CCR5 | 4MBS | CCR9 | 5LWE |
| TM6 | 236 | I | 6.42x42 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 237 | I | 6.43x43 | CCR5 | 4MBS | CXCR2 | 6LFL |
| TM6 | 238 | F | 6.44x44 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM6 | 239 | C | 6.45x45 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 240 | F | 6.46x46 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM6 | 241 | C | 6.47x47 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM6 | 242 | F | 6.48x48 | CCR5 | 4MBS | MT1 receptor | 6ME2 |
| TM6 | 243 | V | 6.49x49 | CCR5 | 4MBS | PAF receptor | 5ZKQ |
| TM6 | 244 | P | 6.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 245 | Y | 6.51x51 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 246 | N | 6.52x52 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 247 | I | 6.53x53 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 248 | N | 6.54x54 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 249 | L | 6.55x55 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 250 | I | 6.56x56 | CCR5 | 4MBS | μ receptor | 4DKL |
| TM6 | 251 | L | 6.57x57 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 252 | Y | 6.58x58 | CCR5 | 4MBS | apelin receptor | 5VBL |
| TM6 | 253 | S | 6.59x59 | CCR5 | 4MBS | CXCR4 | 3ODU |
| TM6 | 254 | L | 6.60x60 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM6 | 255 | V | 6.61x61 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 256 | R | 6.62x62 | CCR5 | 4MBS | CXCR2 | 6LFL |
| TM6 | 257 | T | 6.63x63 | CCR5 | 4MBS | CXCR2 | 6LFL |
| TM6 | 258 | Q | 6.64x64 | CCR5 | 4MBS | GPBA receptor | 7CFN |
| ECL3 | 259 | T | - | - | - | - | - |
| ECL3 | 260 | F | - | LPA6 receptor | 5XSZ | - | - |
| ECL3 | 261 | V | - | - | - | - | - |
| TM7 | 262 | N | 7.24x23 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 263 | C | 7.25x24 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 264 | S | 7.26x25 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 265 | V | 7.27x26 | CCR5 | 4MBS | CCR9 | 5LWE |
| TM7 | 266 | V | 7.28x27 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| TM7 | 267 | A | 7.29x28 | CCR5 | 4MBS | AT2 receptor | 5UNG |
| TM7 | 268 | A | 7.30x29 | CCR5 | 4MBS | CCR9 | 5LWE |
| TM7 | 269 | V | 7.31x30 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM7 | 270 | R | 7.32x31 | CCR5 | 4MBS | BLT1 receptor | 5X33 |
| TM7 | 271 | T | 7.33x32 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM7 | 272 | M | 7.34x33 | CCR5 | 4MBS | - | - |
| TM7 | 273 | Y | 7.35x34 | CCR5 | 4MBS | κ receptor | 4DJH |
| TM7 | 274 | P | 7.36x35 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM7 | 275 | I | 7.37x36 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM7 | 276 | T | 7.38x37 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 277 | L | 7.39x38 | CCR5 | 4MBS | LPA1 receptor | 4Z35 |
| TM7 | 278 | C | 7.40x39 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM7 | 279 | I | 7.41x40 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM7 | 280 | A | 7.42x41 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM7 | 281 | V | 7.43x42 | CCR5 | 4MBS | S1P1 receptor | 3V2Y |
| TM7 | 282 | S | 7.44x43 | CCR5 | 4MBS | NK1 receptor | 6HLP |
| TM7 | 283 | N | 7.45x45 | CCR5 | 4MBS | AT1 receptor | 4ZUD |
| TM7 | 284 | C | 7.46x46 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 285 | C | 7.47x47 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 286 | F | 7.48x48 | CCR5 | 4MBS | β2-adrenoceptor | 2RH1 |
| TM7 | 287 | D | 7.49x49 | CCR5 | 4MBS | EP4 receptor | 5YWY |
| TM7 | 288 | P | 7.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 289 | I | 7.51x51 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 290 | V | 7.52x52 | CCR5 | 4MBS | 5-HT2A receptor | 6A94 |
| TM7 | 291 | Y | 7.53x53 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 292 | Y | 7.54x54 | CCR5 | 4MBS | ETB receptor | 5X93 |
| TM7 | 293 | F | 7.55x55 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 294 | T | 7.56x56 | CCR5 | 4MBS | DP2 receptor | 6D27 |
| H8 | 295 | S | 8.47x47 | CCR5 | 4MBS | ETB receptor | 5X93 |
| H8 | 296 | D | 8.48x48 | CCR5 | 4MBS | NK1 receptor | 6HLP |
| H8 | 297 | T | 8.49x49 | CCR5 | 4MBS | 5-HT2A receptor | 6A94 |
| H8 | 298 | I | 8.50x50 | CCR5 | 4MBS | CB2 receptor | 5ZTY |
| H8 | 299 | Q | 8.51x51 | CCR5 | 4MBS | Y1 receptor | 5ZBH |
| H8 | 300 | N | 8.52x52 | CCR5 | 4MBS | CCR5 | 4MBS |
| H8 | 301 | S | 8.53x53 | CCR5 | 4MBS | α2C-adrenoceptor | 6KUW |
| H8 | 302 | I | 8.54x54 | CCR5 | 4MBS | - | - |
| H8 | 303 | K | 8.55x55 | CCR5 | 4MBS | ETB receptor | 5X93 |
| H8 | 304 | M | 8.56x56 | CCR5 | 4MBS | M5 receptor | 6OL9 |
| H8 | 305 | K | 8.57x57 | CCR5 | 4MBS | EP4 receptor | 5YWY |
| H8 | 306 | N | 8.58x58 | CCR5 | 4MBS | - | - |
| H8 | 307 | W | 8.59x59 | CCR5 | 4MBS | - | - |
| C-term | 308 | S | - | - | - | - | - |
| C-term | 309 | V | - | - | - | - | - |
| C-term | 310 | R | - | - | - | - | - |
| C-term | 311 | R | - | - | - | - | - |
| C-term | 312 | S | - | - | - | - | - |