LPA6 receptor homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Inactive
VERSION
2022-06-19
MODEL
TEMPLATES
6RZ4 (CysLT1 receptor)
4MBS (CCR5)
7O7F (CCR5)
7VL8 (CCR1)
5XSZ (LPA6 receptor)
7T10 (SST2 receptor)
None
4MBS (CCR5)
7O7F (CCR5)
7VL8 (CCR1)
5XSZ (LPA6 receptor)
7T10 (SST2 receptor)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 80.4 | 8.7 | 10.9 |
| Side-chains | 22.1 | 58.3 | 19.6 |
Number of backbone templates: 6
Number of rotamer templates: 40
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 1 | M | - | - | - | - | - |
| N-term | 2 | V | - | - | - | - | - |
| N-term | 3 | S | - | - | - | - | - |
| N-term | 4 | V | - | - | - | - | - |
| TM1 | 5 | N | 1.20x20 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 6 | S | 1.21x21 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 7 | S | 1.22x22 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 8 | H | 1.23x23 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 9 | C | 1.24x24 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 10 | F | 1.25x25 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 11 | Y | 1.26x26 | CysLT1 receptor | 6RZ4 | - | - |
| TM1 | 12 | N | 1.27x27 | CCR5 | 4MBS | - | - |
| TM1 | 13 | D | 1.28x28 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| TM1 | 14 | S | 1.29x29 | CCR5 | 4MBS | GPR183 | 7TUY |
| TM1 | 15 | F | 1.30x30 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| TM1 | 16 | K | 1.31x31 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM1 | 17 | Y | 1.32x32 | CCR5 | 4MBS | PAF receptor | 5ZKQ |
| TM1 | 18 | T | 1.33x33 | CCR5 | 4MBS | PAF receptor | 5ZKQ |
| TM1 | 19 | L | 1.34x34 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 20 | Y | 1.35x35 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM1 | 21 | G | 1.36x36 | CCR5 | 4MBS | β2-adrenoceptor | 3SN6 |
| TM1 | 22 | C | 1.37x37 | CCR5 | 4MBS | MT1 receptor | 7VGZ |
| TM1 | 23 | M | 1.38x38 | CCR5 | 4MBS | BILF1 | 7JHJ |
| TM1 | 24 | F | 1.39x39 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM1 | 25 | S | 1.40x40 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 26 | M | 1.41x41 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| TM1 | 27 | V | 1.42x42 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 28 | F | 1.43x43 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 29 | V | 1.44x44 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| TM1 | 30 | L | 1.45x45 | CCR5 | 4MBS | PAF receptor | 5ZKQ |
| TM1 | 31 | G | 1.46x46 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 32 | L | 1.47x47 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM1 | 33 | I | 1.48x48 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM1 | 34 | S | 1.49x49 | CCR5 | 4MBS | PAR2 | 5NDD |
| TM1 | 35 | N | 1.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 36 | C | 1.51x51 | CCR5 | 4MBS | - | - |
| TM1 | 37 | V | 1.52x52 | CCR5 | 4MBS | P2Y1 receptor | 4XNW |
| TM1 | 38 | A | 1.53x53 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM1 | 39 | I | 1.54x54 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 40 | Y | 1.55x55 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM1 | 41 | I | 1.56x56 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 42 | F | 1.57x57 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM1 | 43 | I | 1.58x58 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM1 | 44 | C | 1.59x59 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM1 | 45 | V | 1.60x60 | CCR5 | 4MBS | - | - |
| ICL1 | 46 | L | 12.48x48 | - | - | - | - |
| ICL1 | 47 | K | 12.49x49 | CCR1 | 7VL8 | Rhodopsin | 4X1H |
| ICL1 | 48 | V | 12.50x50 | CCR1 | 7VL8 | - | - |
| ICL1 | 49 | R | 12.51x51 | - | - | - | - |
| TM2 | 50 | N | 2.37x37 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 51 | E | 2.38x38 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 52 | T | 2.39x39 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 53 | T | 2.40x40 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 54 | T | 2.41x41 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 55 | Y | 2.42x42 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 56 | M | 2.43x43 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 57 | I | 2.44x44 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| TM2 | 58 | N | 2.45x45 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 59 | L | 2.46x46 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 60 | A | 2.47x47 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 61 | M | 2.48x48 | CCR5 | 4MBS | PAF receptor | 5ZKQ |
| TM2 | 62 | S | 2.49x49 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 63 | D | 2.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 64 | L | 2.51x51 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 65 | L | 2.52x52 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 66 | F | 2.53x53 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 67 | V | 2.54x54 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 68 | F | 2.55x55 | CCR5 | 4MBS | CCR1 | 7VL9 |
| TM2 | 69 | T | 2.56x56 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 70 | L | 2.57x57 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 71 | P | 2.58x58 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 72 | F | 2.59x59 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 73 | R | 2.60x60 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 74 | I | 2.61x61 | CCR5 | 4MBS | CCR1 | 7VL9 |
| TM2 | 75 | F | 2.62x62 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 76 | Y | 2.63x63 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM2 | 77 | F | 2.64x64 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM2 | 78 | T | 2.65x65 | CCR5 | 4MBS | GAL2 receptor | 7WQ4 |
| TM2 | 79 | T | 2.66x66 | CCR5 | 4MBS | CCR6 | 6WWZ |
| ECL1 | 80 | R | - | - | - | - | - |
| ECL1 | 81 | N | 23.49x49 | LPA6 receptor | 5XSZ | LPA6 receptor | 5XSZ |
| ECL1 | 82 | W | 23.50x50 | LPA6 receptor | 5XSZ | LPA6 receptor | 5XSZ |
| ECL1 | 83 | P | 23.51x51 | LPA6 receptor | 5XSZ | LPA6 receptor | 5XSZ |
| ECL1 | 84 | F | 23.52x52 | - | - | - | - |
| TM3 | 85 | G | 3.21x21 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 86 | D | 3.22x22 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| TM3 | 87 | L | 3.23x23 | CCR5 | 4MBS | CysLT2 receptor | 6RZ6 |
| TM3 | 88 | L | 3.24x24 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 89 | C | 3.25x25 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 90 | K | 3.26x26 | CCR5 | 4MBS | CCR1 | 7VL9 |
| TM3 | 91 | I | 3.27x27 | CCR5 | 4MBS | CCR1 | 7VL9 |
| TM3 | 92 | S | 3.28x28 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 93 | V | 3.29x29 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 94 | M | 3.30x30 | CCR5 | 4MBS | - | - |
| TM3 | 95 | L | 3.31x31 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 96 | F | 3.32x32 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 97 | Y | 3.33x33 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 98 | T | 3.34x34 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 99 | N | 3.35x35 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 100 | M | 3.36x36 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 101 | Y | 3.37x37 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 102 | G | 3.38x38 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 103 | S | 3.39x39 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 104 | I | 3.40x40 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 105 | L | 3.41x41 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 106 | F | 3.42x42 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 107 | L | 3.43x43 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 108 | T | 3.44x44 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 109 | C | 3.45x45 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 110 | I | 3.46x46 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 111 | S | 3.47x47 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 112 | V | 3.48x48 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 113 | D | 3.49x49 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 114 | R | 3.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 115 | F | 3.51x51 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 116 | L | 3.52x52 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 117 | A | 3.53x53 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 118 | I | 3.54x54 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM3 | 119 | V | 3.55x55 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM3 | 120 | Y | 3.56x56 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| ICL2 | 121 | P | 34.50x50 | - | - | - | - |
| ICL2 | 122 | F | 34.51x51 | LPA6 receptor | 5XSZ | LPA6 receptor | 5XSZ |
| ICL2 | 123 | K | 34.52x52 | LPA6 receptor | 5XSZ | AT1 receptor | 6DO1 |
| ICL2 | 124 | S | 34.53x53 | LPA6 receptor | 5XSZ | LPA6 receptor | 5XSZ |
| ICL2 | 125 | K | 34.54x54 | LPA6 receptor | 5XSZ | ghrelin receptor | 7NA7 |
| ICL2 | 126 | T | 34.55x55 | LPA6 receptor | 5XSZ | CXCR2 | 6LFO |
| ICL2 | 127 | L | 34.56x56 | LPA6 receptor | 5XSZ | LPA6 receptor | 5XSZ |
| ICL2 | 128 | R | 34.57x57 | - | - | - | - |
| TM4 | 129 | T | 4.38x38 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM4 | 130 | K | 4.39x39 | CCR5 | 4MBS | P2Y1 receptor | 4XNW |
| TM4 | 131 | R | 4.40x40 | CCR5 | 4MBS | CysLT2 receptor | 6RZ8 |
| TM4 | 132 | N | 4.41x41 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM4 | 133 | A | 4.42x42 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM4 | 134 | K | 4.43x43 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM4 | 135 | I | 4.44x44 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM4 | 136 | V | 4.45x45 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM4 | 137 | C | 4.46x46 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM4 | 138 | T | 4.47x47 | CCR5 | 4MBS | 5-HT2B receptor | 5TVN |
| TM4 | 139 | G | 4.48x48 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| TM4 | 140 | V | 4.49x49 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM4 | 141 | W | 4.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM4 | 142 | L | 4.51x51 | CCR5 | 4MBS | AT1 receptor | 6DO1 |
| TM4 | 143 | T | 4.52x52 | CCR5 | 4MBS | GPR139 | 7VUG |
| TM4 | 144 | V | 4.53x53 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM4 | 145 | I | 4.54x54 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| TM4 | 146 | G | 4.55x55 | CCR5 | 4MBS | PAF receptor | 5ZKQ |
| TM4 | 147 | G | 4.56x56 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM4 | 148 | S | 4.57x57 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM4 | 149 | A | 4.58x59 | CCR5 | 4MBS | β3-adrenoceptor | 7DH5 |
| TM4 | 150 | P | 4.59x60 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM4 | 151 | A | 4.60x61 | CCR5 | 4MBS | AT1 receptor | 6DO1 |
| TM4 | 152 | V | 4.61x62 | CCR5 | 4MBS | κ receptor | 6B73 |
| TM4 | 153 | F | 4.62x63 | CCR5 | 4MBS | NTS1 receptor | 6OSA |
| TM4 | 154 | V | 4.63x64 | CCR5 | 4MBS | US28 | 7RKN |
| ECL2 | 155 | Q | - | - | - | - | - |
| ECL2 | 156 | S | - | - | - | - | - |
| ECL2 | 157 | T | - | - | - | - | - |
| ECL2 | 158 | H | - | - | - | - | - |
| ECL2 | 159 | S | - | - | - | - | - |
| ECL2 | 160 | Q | - | - | - | - | - |
| ECL2 | 161 | G | - | - | - | - | - |
| ECL2 | 162 | N | - | - | - | - | - |
| ECL2 | 163 | N | - | - | - | - | - |
| ECL2 | 164 | A | - | - | - | - | - |
| ECL2 | 165 | S | - | - | - | - | - |
| ECL2 | 166 | E | - | - | - | - | - |
| ECL2 | 167 | A | - | - | - | - | - |
| ECL2 | 168 | C | 45.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| ECL2 | 169 | F | 45.51x51 | CCR5 | 4MBS | BLT1 receptor | 7VKT |
| ECL2 | 170 | E | 45.52x52 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| ECL2 | 171 | N | - | - | - | - | - |
| ECL2 | 172 | F | - | CysLT1 receptor | 6RZ4 | - | - |
| ECL2 | 173 | P | - | - | - | - | - |
| TM5 | 174 | E | 5.28x29 | CysLT1 receptor | 6RZ4 | - | - |
| TM5 | 175 | A | 5.29x30 | CysLT1 receptor | 6RZ4 | - | - |
| TM5 | 176 | T | 5.30x31 | CCR5 | 4MBS | - | - |
| TM5 | 177 | W | 5.31x32 | CCR5 | 4MBS | - | - |
| TM5 | 178 | K | 5.32x33 | CCR5 | 4MBS | NK1 receptor | 7P00 |
| TM5 | 179 | T | 5.33x34 | CCR5 | 4MBS | FPR2/ALX | 7WVX |
| TM5 | 180 | Y | 5.34x35 | CCR5 | 4MBS | PAR1 | 3VW7 |
| TM5 | 181 | L | 5.35x36 | CCR5 | 4MBS | GPR183 | 7TUZ |
| TM5 | 182 | S | 5.36x37 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 183 | R | 5.37x38 | CCR5 | 4MBS | - | - |
| TM5 | 184 | I | 5.38x39 | CCR5 | 4MBS | GPR183 | 7TUY |
| TM5 | 185 | V | 5.39x40 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 186 | I | 5.40x41 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 187 | F | 5.41x42 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 188 | I | 5.42x43 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 189 | E | 5.43x44 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 190 | I | 5.44x45 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 191 | V | 5.45x46 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 192 | G | 5.46x461 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 193 | F | 5.47x47 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 194 | F | 5.48x48 | CCR5 | 4MBS | PAR1 | 3VW7 |
| TM5 | 195 | I | 5.49x49 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 196 | P | 5.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 197 | L | 5.51x51 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 198 | I | 5.52x52 | CCR5 | 4MBS | GPR183 | 7TUY |
| TM5 | 199 | L | 5.53x53 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 200 | N | 5.54x54 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 201 | V | 5.55x55 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 202 | T | 5.56x56 | CCR5 | 4MBS | AT1 receptor | 6DO1 |
| TM5 | 203 | C | 5.57x57 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 204 | S | 5.58x58 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 205 | S | 5.59x59 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 206 | M | 5.60x60 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 207 | V | 5.61x61 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM5 | 208 | L | 5.62x62 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 209 | K | 5.63x63 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 210 | T | 5.64x64 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 211 | L | 5.65x65 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM5 | 212 | T | 5.66x66 | CCR5 | 4MBS | NTS1 receptor | 6OSA |
| TM5 | 213 | K | 5.67x67 | CCR5 | 4MBS | AT1 receptor | 6OS2 |
| TM5 | 214 | P | 5.68x68 | CCR5 | 7O7F | - | - |
| ICL3 | 215 | V | - | - | - | - | - |
| ICL3 | 216 | T | - | - | - | - | - |
| ICL3 | 217 | L | - | CCR5 | 4MBS | - | - |
| TM6 | 218 | S | 6.24x24 | SST2 receptor | 7T10 | GAL2 receptor | 7WQ4 |
| TM6 | 219 | R | 6.25x25 | SST2 receptor | 7T10 | - | - |
| TM6 | 220 | S | 6.26x26 | SST2 receptor | 7T10 | GAL1 receptor | 7WQ3 |
| TM6 | 221 | K | 6.27x27 | SST2 receptor | 7T10 | MT1 receptor | 7VGZ |
| TM6 | 222 | I | 6.28x28 | CCR5 | 4MBS | - | - |
| TM6 | 223 | N | 6.29x29 | CCR5 | 4MBS | SST2 receptor | 7T10 |
| TM6 | 224 | K | 6.30x30 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 225 | T | 6.31x31 | CCR5 | 4MBS | D1 receptor | 7JVQ |
| TM6 | 226 | K | 6.32x32 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 227 | V | 6.33x33 | CCR5 | 4MBS | SST2 receptor | 7T10 |
| TM6 | 228 | L | 6.34x34 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 229 | K | 6.35x35 | CCR5 | 4MBS | AT1 receptor | 6DO1 |
| TM6 | 230 | M | 6.36x36 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 231 | I | 6.37x37 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 232 | F | 6.38x38 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 233 | V | 6.39x39 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 234 | H | 6.40x40 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 235 | L | 6.41x41 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 236 | I | 6.42x42 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 237 | I | 6.43x43 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 238 | F | 6.44x44 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 239 | C | 6.45x45 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 240 | F | 6.46x46 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 241 | C | 6.47x47 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 242 | F | 6.48x48 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 243 | V | 6.49x49 | CCR5 | 4MBS | PAF receptor | 5ZKQ |
| TM6 | 244 | P | 6.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 245 | Y | 6.51x51 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 246 | N | 6.52x52 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 247 | I | 6.53x53 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 248 | N | 6.54x54 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 249 | L | 6.55x55 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 250 | I | 6.56x56 | CCR5 | 4MBS | GPR183 | 7TUY |
| TM6 | 251 | L | 6.57x57 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM6 | 252 | Y | 6.58x58 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 253 | S | 6.59x59 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 254 | L | 6.60x60 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 255 | V | 6.61x61 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 256 | R | 6.62x62 | CCR5 | 4MBS | P2Y1 receptor | 4XNW |
| TM6 | 257 | T | 6.63x63 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM6 | 258 | Q | 6.64x64 | CCR5 | 4MBS | B1 receptor | 7EIB |
| ECL3 | 259 | T | - | - | - | - | - |
| ECL3 | 260 | F | - | LPA6 receptor | 5XSZ | - | - |
| ECL3 | 261 | V | - | - | - | - | - |
| TM7 | 262 | N | 7.24x23 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 263 | C | 7.25x24 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 264 | S | 7.26x25 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 265 | V | 7.27x26 | CCR5 | 4MBS | AT2 receptor | 5UNG |
| TM7 | 266 | V | 7.28x27 | CCR5 | 4MBS | CysLT1 receptor | 6RZ4 |
| TM7 | 267 | A | 7.29x28 | CCR5 | 4MBS | AT2 receptor | 5UNG |
| TM7 | 268 | A | 7.30x29 | CCR5 | 4MBS | SST2 receptor | 7T10 |
| TM7 | 269 | V | 7.31x30 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 270 | R | 7.32x31 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 271 | T | 7.33x32 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 272 | M | 7.34x33 | CCR5 | 4MBS | GPR139 | 7VUG |
| TM7 | 273 | Y | 7.35x34 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 274 | P | 7.36x35 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 275 | I | 7.37x36 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 276 | T | 7.38x37 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 277 | L | 7.39x38 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 278 | C | 7.40x39 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 279 | I | 7.41x40 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 280 | A | 7.42x41 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 281 | V | 7.43x42 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 282 | S | 7.44x43 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 283 | N | 7.45x45 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 284 | C | 7.46x46 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 285 | C | 7.47x47 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 286 | F | 7.48x48 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 287 | D | 7.49x49 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 288 | P | 7.50x50 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 289 | I | 7.51x51 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 290 | V | 7.52x52 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 291 | Y | 7.53x53 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 292 | Y | 7.54x54 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| TM7 | 293 | F | 7.55x55 | CCR5 | 4MBS | CCR5 | 4MBS |
| TM7 | 294 | T | 7.56x56 | CCR5 | 4MBS | LPA6 receptor | 5XSZ |
| H8 | 295 | S | 8.47x47 | CCR5 | 4MBS | SST2 receptor | 7T10 |
| H8 | 296 | D | 8.48x48 | CCR5 | 4MBS | SST2 receptor | 7T10 |
| H8 | 297 | T | 8.49x49 | CCR5 | 4MBS | 5-HT2B receptor | 5TVN |
| H8 | 298 | I | 8.50x50 | CCR5 | 4MBS | CB2 receptor | 6PT0 |
| H8 | 299 | Q | 8.51x51 | CCR5 | 4MBS | AT2 receptor | 5UNF |
| H8 | 300 | N | 8.52x52 | CCR5 | 4MBS | CCR5 | 4MBS |
| H8 | 301 | S | 8.53x53 | CCR5 | 4MBS | P2Y12 receptor | 4NTJ |
| H8 | 302 | I | 8.54x54 | CCR5 | 4MBS | - | - |
| H8 | 303 | K | 8.55x55 | CCR5 | 4MBS | GAL1 receptor | 7WQ3 |
| H8 | 304 | M | 8.56x56 | CCR5 | 4MBS | - | - |
| H8 | 305 | K | 8.57x57 | CCR5 | 4MBS | succinate receptor | 6RNK |
| H8 | 306 | N | 8.58x58 | CCR5 | 4MBS | - | - |
| H8 | 307 | W | 8.59x59 | CCR5 | 4MBS | - | - |
| C-term | 308 | S | - | - | - | - | - |
| C-term | 309 | V | - | - | - | - | - |
| C-term | 310 | R | - | - | - | - | - |
| C-term | 311 | R | - | - | - | - | - |
| C-term | 312 | S | - | - | - | - | - |