ADGRG4 homology model

PROTEIN CLASS

Class B2 (Adhesion)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active

VERSION

2021-04-08

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

NGL is a WebGL based 3D viewer powered by MMTF.

MAIN TEMPLATE

ADGRG3 (sequence similarity: 5%) PDB: 7D77

TEMPLATES

7D77 (ADGRG3)
6P9Y (PAC1 receptor)
6PB1 (CRF2 receptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 82.1 7.2 10.8
Side-chains 31.2 26.2 42.7

Number of backbone templates: 3
Number of rotamer templates: 16

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 2733 S - - - - -
N-term 2734 T - - - - -
N-term 2735 V - - - - -
N-term 2736 D - - - - -
N-term 2737 S - - - - -
TM1 2738 V 1.34x34 ADGRG3 7D77 CRF1 receptor 4Z9G
TM1 2739 N 1.35x35 ADGRG3 7D77 CT receptor 6NIY
TM1 2740 E 1.36x36 ADGRG3 7D77 - -
TM1 2741 Q 1.37x37 ADGRG3 7D77 - -
TM1 2742 I 1.38x38 ADGRG3 7D77 ADGRG3 7D77
TM1 2743 L 1.39x39 ADGRG3 7D77 ADGRG3 7D77
TM1 2744 A 1.40x40 ADGRG3 7D77 PTH1 receptor 6NBI
TM1 2745 L 1.41x41 ADGRG3 7D77 - -
TM1 2746 I 1.42x42 ADGRG3 7D77 ADGRG3 7D77
TM1 2747 T 1.43x43 ADGRG3 7D77 calcitonin receptor-like receptor 6UVA
TM1 2748 Y 1.44x44 ADGRG3 7D77 CRF2 receptor 6PB1
TM1 2749 T 1.45x45 ADGRG3 7D77 - -
TM1 2750 G 1.46x46 ADGRG3 7D77 ADGRG3 7D77
TM1 2751 C 1.47x47 ADGRG3 7D77 ADGRG3 7D77
TM1 2752 G 1.48x48 ADGRG3 7D77 ADGRG3 7D77
TM1 2753 I 1.49x49 ADGRG3 7D77 CRF1 receptor 6PB0
TM1 2754 S 1.50x50 ADGRG3 7D77 ADGRG3 7D77
TM1 2755 S 1.51x51 ADGRG3 7D77 - -
TM1 2756 I 1.52x52 ADGRG3 7D77 ADGRG3 7D77
TM1 2757 F 1.53x53 ADGRG3 7D77 ADGRG3 7D77
TM1 2758 L 1.54x54 ADGRG3 7D77 ADGRG3 7D77
TM1 2759 G 1.55x55 ADGRG3 7D77 - -
TM1 2760 V 1.56x56 ADGRG3 7D77 CRF1 receptor 6PB0
TM1 2761 A 1.57x57 ADGRG3 7D77 CRF2 receptor 6PB1
TM1 2762 V 1.58x58 ADGRG3 7D77 PTH1 receptor 6NBI
TM1 2763 V 1.59x59 ADGRG3 7D77 CRF1 receptor 6PB0
TM1 2764 T 1.60x60 ADGRG3 7D77 - -
TM1 2765 Y 1.61x61 ADGRG3 7D77 ADGRG3 7D77
TM1 2766 I 1.62x62 ADGRG3 7D77 - -
TM1 2767 A 1.63x63 ADGRG3 7D77 CRF2 receptor 6PB1
TM1 2768 F 1.64x64 ADGRG3 7D77 PAC1 receptor 6M1I
ICL1 2769 H 12.48x48 ADGRG3 7D77 - -
ICL1 2770 K 12.49x49 ADGRG3 7D77 glucagon receptor 6WPW
ICL1 2771 L 12.50x50 ADGRG3 7D77 calcitonin receptor-like receptor 6UVA
ICL1 2772 R 12.51x51 ADGRG3 7D77 CRF2 receptor 6PB1
ICL1 2773 K - ADGRG3 7D77 - -
TM2 2774 D 2.44x44 ADGRG3 7D77 - -
TM2 2775 Y 2.45x45 ADGRG3 7D77 - -
TM2 2776 P 2.46x46 ADGRG3 7D77 - -
TM2 2777 A 2.47x47 ADGRG3 7D77 - -
TM2 2778 K 2.48x48 ADGRG3 7D77 ADGRG3 7D77
TM2 2779 I 2.49x49 ADGRG3 7D77 ADGRG3 7D77
TM2 2780 L 2.50x50 ADGRG3 7D77 - -
TM2 2781 I 2.51x51 ADGRG3 7D77 - -
TM2 2782 N 2.52x52 ADGRG3 7D77 CRF2 receptor 6PB1
TM2 2783 L 2.53x53 ADGRG3 7D77 ADGRG3 7D77
TM2 2784 C 2.54x54 ADGRG3 7D77 - -
TM2 2785 T 2.55x55 ADGRG3 7D77 CRF2 receptor 6PB1
TM2 2786 A 2.56x56 ADGRG3 7D77 CRF1 receptor 6PB0
TM2 2787 L 2.57x57 ADGRG3 7D77 ADGRG3 7D77
TM2 2788 L 2.58x58 ADGRG3 7D77 - -
TM2 2789 M 2.59x59 ADGRG3 7D77 - -
TM2 2790 L 2.60x60 ADGRG3 7D77 ADGRG3 7D77
TM2 2791 N 2.61x61 ADGRG3 7D77 ADGRG3 7D77
TM2 2792 L 2.62x62 ADGRG3 7D77 ADGRG3 7D77
TM2 2793 V 2.63x63 ADGRG3 7D77 calcitonin receptor-like receptor 6UVA
TM2 2794 F 2.64x64 ADGRG3 7D77 ADGRG3 7D77
TM2 2795 L 2.65x65 ADGRG3 7D77 ADGRG3 7D77
TM2 2796 I 2.66x66 ADGRG3 7D77 PAC1 receptor 6P9Y
TM2 2797 N 2.67x67 ADGRG3 7D77 ADGRG3 7D77
TM2 2798 S 2.68x68 ADGRG3 7D77 - -
TM2 2799 W 2.69x69 ADGRG3 7D77 PAC1 receptor 6P9Y
TM2 2800 L 2.70x70 ADGRG3 7D77 glucagon receptor 6WPW
ECL1 2801 S - ADGRG3 7D77 - -
ECL1 2802 S - ADGRG3 7D77 ADGRG3 7D77
ECL1 2803 F - ADGRG3 7D77 - -
ECL1 2804 Q - ADGRG3 7D77 - -
TM3 2805 K 3.25x25 ADGRG3 7D77 - -
TM3 2806 V 3.26x26 ADGRG3 7D77 glucagon receptor 6WPW
TM3 2807 G 3.27x27 ADGRG3 7D77 CRF1 receptor 6PB0
TM3 2808 V 3.28x28 ADGRG3 7D77 - -
TM3 2809 C 3.29x29 ADGRG3 7D77 ADGRG3 7D77
TM3 2810 I 3.30x30 ADGRG3 7D77 - -
TM3 2811 T 3.31x31 ADGRG3 7D77 - -
TM3 2812 A 3.32x32 ADGRG3 7D77 glucagon receptor 6WPW
TM3 2813 A 3.33x33 ADGRG3 7D77 glucagon receptor 6WPW
TM3 2814 V 3.34x34 ADGRG3 7D77 PAC1 receptor 6P9Y
TM3 2815 A 3.35x35 ADGRG3 7D77 CRF1 receptor 6PB0
TM3 2816 L 3.36x36 ADGRG3 7D77 - -
TM3 2817 H 3.37x37 ADGRG3 7D77 ADGRG3 7D77
TM3 2818 Y 3.38x38 ADGRG3 7D77 ADGRG3 7D77
TM3 2819 F 3.39x39 ADGRG3 7D77 ADGRG3 7D77
TM3 2820 L 3.40x40 ADGRG3 7D77 ADGRG3 7D77
TM3 2821 L 3.41x41 ADGRG3 7D77 ADGRG3 7D77
TM3 2822 V 3.42x42 ADGRG3 7D77 - -
TM3 2823 S 3.43x43 ADGRG3 7D77 - -
TM3 2824 F 3.44x44 ADGRG3 7D77 ADGRG3 7D77
TM3 2825 T 3.45x45 ADGRG3 7D77 ADGRG3 7D77
TM3 2826 W 3.46x46 ADGRG3 7D77 ADGRG3 7D77
TM3 2827 M 3.47x47 ADGRG3 7D77 ADGRG3 7D77
TM3 2828 G 3.48x48 ADGRG3 7D77 ADGRG3 7D77
TM3 2829 L 3.49x49 ADGRG3 7D77 ADGRG3 7D77
TM3 2830 E 3.50x50 ADGRG3 7D77 ADGRG3 7D77
TM3 2831 A 3.51x51 ADGRG3 7D77 ADGRG3 7D77
TM3 2832 V 3.52x52 ADGRG3 7D77 GLP-1 receptor 6X19
TM3 2833 H 3.53x53 ADGRG3 7D77 ADGRG3 7D77
TM3 2834 M 3.54x54 ADGRG3 7D77 - -
TM3 2835 Y 3.55x55 ADGRG3 7D77 ADGRG3 7D77
TM3 2836 L 3.56x56 ADGRG3 7D77 ADGRG3 7D77
TM3 2837 A 3.57x57 ADGRG3 7D77 CRF2 receptor 6PB1
TM3 2838 L 3.58x58 ADGRG3 7D77 PAC1 receptor 6P9Y
TM3 2839 V 3.59x59 ADGRG3 7D77 ADGRG3 7D77
TM3 2840 K 3.60x60 ADGRG3 7D77 PTH1 receptor 6FJ3
ICL2 2841 V - ADGRG3 7D77 ADGRG3 7D77
ICL2 2842 F - ADGRG3 7D77 ADGRG3 7D77
ICL2 2843 N - ADGRG3 7D77 ADGRG3 7D77
ICL2 2844 I - ADGRG3 7D77 - -
ICL2 2845 Y - ADGRG3 7D77 ADGRG3 7D77
ICL2 2846 I - ADGRG3 7D77 - -
ICL2 2847 P - ADGRG3 7D77 - -
TM4 2848 N 4.40x41 ADGRG3 7D77 - -
TM4 2849 Y 4.41x42 ADGRG3 7D77 ADGRG3 7D77
TM4 2850 I 4.42x43 ADGRG3 7D77 - -
TM4 2851 L 4.43x44 ADGRG3 7D77 ADGRG3 7D77
TM4 2852 K 4.44x45 ADGRG3 7D77 ADGRG3 7D77
TM4 2853 F 4.45x46 ADGRG3 7D77 CRF2 receptor 6PB1
TM4 2854 C 4.46x47 ADGRG3 7D77 - -
TM4 2855 L 4.47x48 ADGRG3 7D77 ADGRG3 7D77
TM4 2856 V 4.48x49 ADGRG3 7D77 ADGRG3 7D77
TM4 2857 G 4.49x491 ADGRG3 7D77 ADGRG3 7D77
TM4 2858 W 4.50x50 ADGRG3 7D77 ADGRG3 7D77
TM4 2859 G 4.51x51 ADGRG3 7D77 ADGRG3 7D77
TM4 2860 I 4.52x52 ADGRG3 7D77 CRF2 receptor 6PB1
TM4 2861 P 4.53x53 ADGRG3 7D77 ADGRG3 7D77
TM4 2862 A 4.54x54 ADGRG3 7D77 ADGRG3 7D77
TM4 2863 I 4.55x55 ADGRG3 7D77 calcitonin receptor-like receptor 6UVA
TM4 2864 M 4.56x56 ADGRG3 7D77 ADGRG3 7D77
TM4 2865 V 4.57x57 ADGRG3 7D77 ADGRG3 7D77
TM4 2866 A 4.58x58 ADGRG3 7D77 secretin receptor 6WZG
TM4 2867 I 4.59x59 ADGRG3 7D77 calcitonin receptor-like receptor 6UVA
TM4 2868 T 4.60x60 ADGRG3 7D77 ADGRG3 7D77
TM4 2869 V 4.61x61 ADGRG3 7D77 PTH1 receptor 6NBI
TM4 2870 S 4.62x62 ADGRG3 7D77 ADGRG3 7D77
TM4 2871 V 4.63x63 ADGRG3 7D77 glucagon receptor 6WPW
TM4 2872 K 4.64x64 ADGRG3 7D77 CRF1 receptor 6PB0
ECL2 2873 K - - - - -
ECL2 2874 D - - - - -
ECL2 2875 L - - - - -
ECL2 2876 Y - - - - -
ECL2 2877 G - - - - -
ECL2 2878 T - - - - -
ECL2 2879 L - - - - -
ECL2 2880 S - - - - -
ECL2 2881 P - - - - -
ECL2 2882 T - - - - -
ECL2 2883 T - - - - -
ECL2 2884 P - - - - -
ECL2 2885 F - - - - -
ECL2 2886 C 45.50x50 ADGRG3 7D77 ADGRG3 7D77
ECL2 2887 W 45.51x51 ADGRG3 7D77 ADGRG3 7D77
ECL2 2888 I 45.52x52 ADGRG3 7D77 calcitonin receptor-like receptor 6E3Y
ECL2 2889 K - - - - -
ECL2 2890 D - PAC1 receptor 6P9Y - -
ECL2 2891 D - - - - -
TM5 2892 S 5.33x34 ADGRG3 7D77 VPAC1 receptor 6VN7
TM5 2893 I 5.34x35 ADGRG3 7D77 - -
TM5 2894 F 5.35x36 ADGRG3 7D77 glucagon receptor 6WPW
TM5 2895 Y 5.36x37 ADGRG3 7D77 ADGRG3 7D77
TM5 2896 I 5.37x38 ADGRG3 7D77 ADGRG3 7D77
TM5 2897 S 5.38x381 ADGRG3 7D77 - -
TM5 2898 V 5.39x39 ADGRG3 7D77 ADGRG3 7D77
TM5 2899 V 5.40x40 ADGRG3 7D77 - -
TM5 2900 A 5.41x41 ADGRG3 7D77 - -
TM5 2901 Y 5.42x42 ADGRG3 7D77 ADGRG3 7D77
TM5 2902 F 5.43x43 ADGRG3 7D77 ADGRG3 7D77
TM5 2903 C 5.44x44 ADGRG3 7D77 calcitonin receptor-like receptor 6UVA
TM5 2904 L 5.45x45 ADGRG3 7D77 CRF2 receptor 6PB1
TM5 2905 I 5.46x46 ADGRG3 7D77 - -
TM5 2906 F 5.47x47 ADGRG3 7D77 ADGRG3 7D77
TM5 2907 L 5.48x48 ADGRG3 7D77 ADGRG3 7D77
TM5 2908 M 5.49x49 ADGRG3 7D77 - -
TM5 2909 N 5.50x50 ADGRG3 7D77 CRF2 receptor 6PB1
TM5 2910 L 5.51x51 ADGRG3 7D77 calcitonin receptor-like receptor 6UVA
TM5 2911 S 5.52x52 ADGRG3 7D77 - -
TM5 2912 M 5.53x53 ADGRG3 7D77 - -
TM5 2913 F 5.54x54 ADGRG3 7D77 PAC1 receptor 6P9Y
TM5 2914 C 5.55x55 ADGRG3 7D77 - -
TM5 2915 T 5.56x56 ADGRG3 7D77 - -
TM5 2916 V 5.57x57 ADGRG3 7D77 ADGRG3 7D77
TM5 2917 L 5.58x58 ADGRG3 7D77 secretin receptor 6WZG
TM5 2918 V 5.59x59 ADGRG3 7D77 PAC1 receptor 6P9Y
TM5 2919 Q 5.60x60 ADGRG3 7D77 - -
TM5 2920 L 5.61x61 ADGRG3 7D77 CRF2 receptor 6PB1
TM5 2921 N 5.62x62 ADGRG3 7D77 - -
TM5 2922 S 5.63x63 ADGRG3 7D77 GLP-1 receptor 6X19
TM5 2923 V 5.64x64 ADGRG3 7D77 - -
TM5 2924 K 5.65x65 ADGRG3 7D77 - -
TM5 2925 S 5.66x66 ADGRG3 7D77 - -
TM5 2926 Q 5.67x67 ADGRG3 7D77 - -
TM5 2927 I 5.68x68 ADGRG3 7D77 - -
ICL3 2928 Q - ADGRG3 7D77 - -
ICL3 2929 K - ADGRG3 7D77 - -
ICL3 2930 T - ADGRG3 7D77 - -
ICL3 2931 R - ADGRG3 7D77 - -
ICL3 2932 R - ADGRG3 7D77 ADGRG3 7D77
ICL3 2933 K - ADGRG3 7D77 - -
TM6 2934 M 6.34x34 ADGRG3 7D77 CT receptor 6NIY
TM6 2935 I 6.35x35 ADGRG3 7D77 - -
TM6 2936 L 6.36x36 ADGRG3 7D77 PAC1 receptor 6P9Y
TM6 2937 H 6.37x37 ADGRG3 7D77 - -
TM6 2938 D 6.38x38 ADGRG3 7D77 - -
TM6 2939 L 6.39x39 ADGRG3 7D77 PTH1 receptor 6NBI
TM6 2940 K 6.40x40 ADGRG3 7D77 CRF2 receptor 6PB1
TM6 2941 G 6.41x41 ADGRG3 7D77 - -
TM6 2942 T 6.42x42 ADGRG3 7D77 CRF2 receptor 6PB1
TM6 2943 M 6.43x43 ADGRG3 7D77 CT receptor 6NIY
TM6 2944 S 6.44x44 ADGRG3 7D77 - -
TM6 2945 L 6.45x45 ADGRG3 7D77 ADGRG3 7D77
TM6 2946 T 6.46x46 ADGRG3 7D77 - -
TM6 2947 F 6.47x47 ADGRG3 7D77 - -
TM6 2948 L 6.48x48 ADGRG3 7D77 ADGRG3 7D77
TM6 2949 L 6.49x49 ADGRG3 7D77 CRF2 receptor 6PB1
TM6 2950 G 6.50x50 ADGRG3 7D77 ADGRG3 7D77
TM6 2951 L 6.51x51 ADGRG3 7D77 - -
TM6 2952 T 6.52x52 ADGRG3 7D77 ADGRG3 7D77
TM6 2953 W 6.53x53 ADGRG3 7D77 ADGRG3 7D77
TM6 2954 G 6.54x54 ADGRG3 7D77 ADGRG3 7D77
TM6 2955 F 6.55x55 ADGRG3 7D77 - -
TM6 2956 A 6.56x56 ADGRG3 7D77 ADGRG3 7D77
TM6 2957 F 6.57x57 ADGRG3 7D77 CRF1 receptor 4Z9G
TM6 2958 F 6.58x58 ADGRG3 7D77 ADGRG3 7D77
ECL3 2959 A - - - - -
ECL3 2960 W - - - - -
ECL3 2961 G - - - - -
ECL3 2962 P - - - - -
ECL3 2963 M - - - - -
TM7 2964 R 7.35x34 CRF2 receptor 6PB1 CRF1 receptor 6PB0
TM7 2965 N 7.36x35 CRF2 receptor 6PB1 - -
TM7 2966 F 7.37x36 CRF2 receptor 6PB1 - -
TM7 2967 F 7.38x37 ADGRG3 7D77 CRF2 receptor 6PB1
TM7 2968 L 7.39x38 ADGRG3 7D77 PAC1 receptor 6P9Y
TM7 2969 Y 7.40x39 ADGRG3 7D77 ADGRG3 7D77
TM7 2970 L 7.41x40 ADGRG3 7D77 GHRH receptor 7CZ5
TM7 2971 F 7.42x41 ADGRG3 7D77 ADGRG3 7D77
TM7 2972 A 7.43x42 ADGRG3 7D77 ADGRG3 7D77
TM7 2973 I 7.44x43 ADGRG3 7D77 calcitonin receptor-like receptor 6UVA
TM7 2974 F 7.45x44 ADGRG3 7D77 ADGRG3 7D77
TM7 2975 N 7.46x45 ADGRG3 7D77 ADGRG3 7D77
TM7 2976 T 7.47x46 ADGRG3 7D77 - -
TM7 2977 L 7.48x47 ADGRG3 7D77 ADGRG3 7D77
TM7 2978 Q 7.49x49 ADGRG3 7D77 ADGRG3 7D77
TM7 2979 G 7.50x50 ADGRG3 7D77 ADGRG3 7D77
TM7 2980 F 7.51x51 ADGRG3 7D77 CRF2 receptor 6PB1
TM7 2981 F 7.52x52 ADGRG3 7D77 ADGRG3 7D77
TM7 2982 I 7.53x53 ADGRG3 7D77 ADGRG3 7D77
TM7 2983 F 7.54x54 ADGRG3 7D77 - -
TM7 2984 V 7.55x55 ADGRG3 7D77 CRF2 receptor 6PB1
TM7 2985 F 7.56x56 ADGRG3 7D77 CRF2 receptor 6PB1
TM7 2986 H 7.57x57 ADGRG3 7D77 - -
TM7 2987 C 7.58x58 ADGRG3 7D77 CRF2 receptor 6PB1
TM7 2988 V 7.59x59 ADGRG3 7D77 - -
TM7 2989 M 7.60x60 ADGRG3 7D77 - -
TM7 2990 K 7.61x61 ADGRG3 7D77 - -
H8 2991 E 8.48x48 CRF2 receptor 6PB1 - -
H8 2992 S 8.49x49 CRF2 receptor 6PB1 - -
H8 2993 V 8.50x50 CRF2 receptor 6PB1 CRF2 receptor 6PB1
H8 2994 R 8.51x51 CRF2 receptor 6PB1 CRF2 receptor 6PB1
H8 2995 E 8.52x52 CRF2 receptor 6PB1 - -
H8 2996 Q 8.53x53 CRF2 receptor 6PB1 - -
H8 2997 W 8.54x54 CRF2 receptor 6PB1 - -
H8 2998 Q 8.55x55 CRF2 receptor 6PB1 secretin receptor 6WZG
H8 2999 I 8.56x56 CRF2 receptor 6PB1 - -
H8 3000 H 8.57x57 CRF2 receptor 6PB1 - -
H8 3001 L 8.58x58 CRF2 receptor 6PB1 - -
H8 3002 C 8.59x59 CRF2 receptor 6PB1 - -
H8 3003 C 8.60x60 CRF2 receptor 6PB1 - -
H8 3004 G 8.61x61 CRF2 receptor 6PB1 - -
H8 3005 W 8.62x62 CRF2 receptor 6PB1 - -
H8 3006 L 8.63x63 CRF2 receptor 6PB1 glucagon receptor 6WPW
C-term 3007 R - - - - -
C-term 3008 L - - - - -
C-term 3009 D - - - - -
C-term 3010 N - - - - -
C-term 3011 S - - - - -