MRGPRD homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Active
VERSION
2021-01-08
MODEL
TEMPLATES
6WWZ (CCR6)
5O9H (C5a1 receptor)
5XSZ (LPA6 receptor)
4XNW (P2Y1 receptor)
6MEO (CCR5)
5NDD (PAR2)
3VG9 (A2A receptor)
None
5O9H (C5a1 receptor)
5XSZ (LPA6 receptor)
4XNW (P2Y1 receptor)
6MEO (CCR5)
5NDD (PAR2)
3VG9 (A2A receptor)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 84.3 | 8.0 | 7.7 |
| Side-chains | 19.2 | 59.1 | 21.7 |
Number of backbone templates: 7
Number of rotamer templates: 55
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 15 | L | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| N-term | 16 | N | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| N-term | 17 | Y | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| N-term | 18 | S | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| N-term | 19 | R | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| TM1 | 20 | G | 1.25x25 | CCR6 | 6WWZ | - | - |
| TM1 | 21 | S | 1.26x26 | CCR6 | 6WWZ | - | - |
| TM1 | 22 | T | 1.27x27 | CCR6 | 6WWZ | - | - |
| TM1 | 23 | V | 1.28x28 | CCR6 | 6WWZ | - | - |
| TM1 | 24 | H | 1.29x29 | CCR6 | 6WWZ | - | - |
| TM1 | 25 | T | 1.30x30 | CCR6 | 6WWZ | ETB receptor | 5X93 |
| TM1 | 26 | A | 1.31x31 | CCR6 | 6WWZ | CCR5 | 5UIW |
| TM1 | 27 | Y | 1.32x32 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM1 | 28 | L | 1.33x33 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 29 | V | 1.34x34 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM1 | 30 | L | 1.35x35 | CCR6 | 6WWZ | Rhodopsin | 4ZWJ |
| TM1 | 31 | S | 1.36x36 | CCR6 | 6WWZ | CysLT1 receptor | 6RZ4 |
| TM1 | 32 | S | 1.37x37 | CCR6 | 6WWZ | PAR1 | 3VW7 |
| TM1 | 33 | L | 1.38x38 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM1 | 34 | A | 1.39x39 | CCR6 | 6WWZ | M2 receptor | 4MQT |
| TM1 | 35 | M | 1.40x40 | CCR6 | 6WWZ | apelin receptor | 5VBL |
| TM1 | 36 | F | 1.41x41 | CCR6 | 6WWZ | α2B-adrenoceptor | 6K41 |
| TM1 | 37 | T | 1.42x42 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM1 | 38 | C | 1.43x43 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 39 | L | 1.44x44 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM1 | 40 | C | 1.45x45 | CCR6 | 6WWZ | - | - |
| TM1 | 41 | G | 1.46x46 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 42 | M | 1.47x47 | CCR6 | 6WWZ | succinate receptor | 6RNK |
| TM1 | 43 | A | 1.48x48 | CCR6 | 6WWZ | GPR52 | 6LI3 |
| TM1 | 44 | G | 1.49x49 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 45 | N | 1.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 46 | S | 1.51x51 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM1 | 47 | M | 1.52x52 | CCR6 | 6WWZ | PAR2 | 5NDD |
| TM1 | 48 | V | 1.53x53 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 49 | I | 1.54x54 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM1 | 50 | W | 1.55x55 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM1 | 51 | L | 1.56x56 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM1 | 52 | L | 1.57x57 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM1 | 53 | G | 1.58x58 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM1 | 54 | F | 1.59x59 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 55 | R | 1.60x60 | CCR6 | 6WWZ | - | - |
| ICL1 | 56 | M | - | - | - | - | |
| ICL1 | 57 | H | C5a1 receptor | 5O9H | - | - | |
| ICL1 | 58 | R | - | - | - | - | |
| TM2 | 59 | N | 2.37x37 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM2 | 60 | P | 2.38x38 | CCR6 | 6WWZ | Rhodopsin | 4ZWJ |
| TM2 | 61 | F | 2.39x39 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM2 | 62 | C | 2.40x40 | CCR6 | 6WWZ | - | - |
| TM2 | 63 | I | 2.41x41 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM2 | 64 | Y | 2.42x42 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 65 | I | 2.43x43 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM2 | 66 | L | 2.44x44 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 67 | N | 2.45x45 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 68 | L | 2.46x46 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM2 | 69 | A | 2.47x47 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 70 | A | 2.48x48 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM2 | 71 | A | 2.49x49 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 72 | D | 2.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 73 | L | 2.51x51 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM2 | 74 | L | 2.52x52 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 75 | F | 2.53x53 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 76 | L | 2.54x54 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM2 | 77 | F | 2.55x55 | CCR6 | 6WWZ | Rhodopsin | 5DYS |
| TM2 | 78 | S | 2.56x56 | CCR6 | 6WWZ | M1 receptor | 6OIJ |
| TM2 | 79 | M | 2.57x57 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM2 | 80 | A | 2.58x58 | CCR6 | 6WWZ | CB2 receptor | 6PT0 |
| TM2 | 81 | S | 2.59x59 | CCR6 | 6WWZ | Rhodopsin | 4ZWJ |
| TM2 | 82 | T | 2.60x60 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM2 | 83 | L | 2.61x61 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM2 | 84 | S | 2.62x62 | CCR6 | 6WWZ | PAR1 | 3VW7 |
| TM2 | 85 | L | 2.63x63 | CCR6 | 6WWZ | D2 receptor | 6VMS |
| TM2 | 86 | E | 2.64x64 | CCR6 | 6WWZ | α2B-adrenoceptor | 6K41 |
| TM2 | 87 | T | 2.65x65 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM2 | 88 | Q | 2.66x66 | CCR6 | 6WWZ | C5a1 receptor | 5O9H |
| ECL1 | 89 | P | - | - | - | - | |
| ECL1 | 90 | L | LPA6 receptor | 5XSZ | - | - | |
| ECL1 | 91 | V | LPA6 receptor | 5XSZ | - | - | |
| ECL1 | 92 | N | LPA6 receptor | 5XSZ | - | - | |
| ECL1 | 93 | T | - | - | - | - | |
| TM3 | 94 | T | 3.21x21 | CCR6 | 6WWZ | S1P1 receptor | 3V2Y |
| TM3 | 95 | D | 3.22x22 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM3 | 96 | K | 3.23x23 | CCR6 | 6WWZ | 5-HT2A receptor | 6A94 |
| TM3 | 97 | V | 3.24x24 | CCR6 | 6WWZ | CB1 receptor | 6N4B |
| TM3 | 98 | H | 3.25x25 | CCR6 | 6WWZ | - | - |
| TM3 | 99 | E | 3.26x26 | CCR6 | 6WWZ | α2B-adrenoceptor | 6K41 |
| TM3 | 100 | L | 3.27x27 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 101 | M | 3.28x28 | CCR6 | 6WWZ | CysLT2 receptor | 6RZ6 |
| TM3 | 102 | K | 3.29x29 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 103 | R | 3.30x30 | CCR6 | 6WWZ | - | - |
| TM3 | 104 | L | 3.31x31 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM3 | 105 | M | 3.32x32 | CCR6 | 6WWZ | EP3 receptor | 6M9T |
| TM3 | 106 | Y | 3.33x33 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM3 | 107 | F | 3.34x34 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM3 | 108 | A | 3.35x35 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM3 | 109 | Y | 3.36x36 | CCR6 | 6WWZ | CCR2 | 5T1A |
| TM3 | 110 | T | 3.37x37 | CCR6 | 6WWZ | CB1 receptor | 5XRA |
| TM3 | 111 | V | 3.38x38 | CCR6 | 6WWZ | GPR52 | 6LI3 |
| TM3 | 112 | G | 3.39x39 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 113 | L | 3.40x40 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM3 | 114 | S | 3.41x41 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM3 | 115 | L | 3.42x42 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 116 | L | 3.43x43 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 117 | T | 3.44x44 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 118 | A | 3.45x45 | CCR6 | 6WWZ | α2B-adrenoceptor | 6K41 |
| TM3 | 119 | I | 3.46x46 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 120 | S | 3.47x47 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 121 | T | 3.48x48 | CCR6 | 6WWZ | - | - |
| TM3 | 122 | Q | 3.49x49 | CCR6 | 6WWZ | PAR2 | 5NDD |
| TM3 | 123 | R | 3.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 124 | C | 3.51x51 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM3 | 125 | L | 3.52x52 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM3 | 126 | S | 3.53x53 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM3 | 127 | V | 3.54x54 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM3 | 128 | L | 3.55x55 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM3 | 129 | F | 3.56x56 | C5a1 receptor | 5O9H | CysLT1 receptor | 6RZ4 |
| ICL2 | 130 | P | 34.50x50 | - | - | - | - |
| ICL2 | 131 | I | 34.51x51 | C5a1 receptor | 5O9H | 5-HT2A receptor | 6WHA |
| ICL2 | 132 | W | 34.52x52 | C5a1 receptor | 5O9H | C5a1 receptor | 5O9H |
| ICL2 | 133 | F | 34.53x53 | C5a1 receptor | 5O9H | - | - |
| ICL2 | 134 | K | 34.54x54 | C5a1 receptor | 5O9H | NTS1 receptor | 4XES |
| ICL2 | 135 | C | 34.55x55 | C5a1 receptor | 5O9H | - | - |
| ICL2 | 136 | H | 34.56x56 | C5a1 receptor | 5O9H | FPR2/ALX | 6LW5 |
| ICL2 | 137 | R | 34.57x57 | - | - | - | - |
| TM4 | 138 | P | 4.38x38 | C5a1 receptor | 5O9H | US28 | 5WB1 |
| TM4 | 139 | R | 4.39x39 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM4 | 140 | H | 4.40x40 | CCR6 | 6WWZ | - | - |
| TM4 | 141 | L | 4.41x41 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM4 | 142 | S | 4.42x42 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 143 | A | 4.43x43 | CCR6 | 6WWZ | M1 receptor | 6OIJ |
| TM4 | 144 | W | 4.44x44 | CCR6 | 6WWZ | BLT1 receptor | 5X33 |
| TM4 | 145 | V | 4.45x45 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM4 | 146 | C | 4.46x46 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 147 | G | 4.47x47 | CCR6 | 6WWZ | CB2 receptor | 6PT0 |
| TM4 | 148 | L | 4.48x48 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM4 | 149 | L | 4.49x49 | CCR6 | 6WWZ | DP2 receptor | 6D27 |
| TM4 | 150 | W | 4.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 151 | T | 4.51x51 | CCR6 | 6WWZ | CB1 receptor | 5XRA |
| TM4 | 152 | L | 4.52x52 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 153 | C | 4.53x53 | CCR6 | 6WWZ | MC4 receptor | 6W25 |
| TM4 | 154 | L | 4.54x54 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM4 | 155 | L | 4.55x55 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM4 | 156 | M | 4.56x56 | CCR6 | 6WWZ | LPA1 receptor | 4Z35 |
| TM4 | 157 | N | 4.57x57 | P2Y1 receptor | 4XNW | - | - |
| TM4 | 158 | G | 4.58x58 | P2Y1 receptor | 4XNW | S1P1 receptor | 3V2Y |
| TM4 | 159 | L | 4.59x59 | P2Y1 receptor | 4XNW | AT1 receptor | 6OS2 |
| TM4 | 160 | T | 4.60x60 | CCR6 | 6WWZ | LPA6 receptor | 5XSZ |
| TM4 | 161 | S | 4.61x61 | CCR6 | 6WWZ | GPR52 | 6LI3 |
| TM4 | 162 | S | 4.62x62 | CCR6 | 6WWZ | - | - |
| TM4 | 163 | F | 4.63x63 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM4 | 164 | C | 4.64x64 | CCR6 | 6WWZ | - | - |
| ECL2 | 165 | S | - | - | - | - | |
| ECL2 | 166 | K | - | - | - | - | |
| ECL2 | 167 | F | - | - | - | - | |
| ECL2 | 168 | L | - | - | - | - | |
| ECL2 | 169 | K | - | - | - | - | |
| ECL2 | 170 | F | - | - | - | - | |
| ECL2 | 171 | N | - | - | - | - | |
| ECL2 | 172 | E | - | - | - | - | |
| TM5 | 173 | D | 5.31x32 | CCR6 | 6WWZ | - | - |
| TM5 | 174 | R | 5.32x33 | CCR6 | 6WWZ | - | - |
| TM5 | 175 | C | 5.33x34 | CCR6 | 6WWZ | - | - |
| TM5 | 176 | F | 5.34x35 | CCR6 | 6WWZ | - | - |
| TM5 | 177 | R | 5.35x36 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM5 | 178 | V | 5.36x37 | CCR6 | 6WWZ | CXCR4 | 3ODU |
| TM5 | 179 | D | 5.37x38 | CCR6 | 6WWZ | CB2 receptor | 6PT0 |
| TM5 | 180 | M | 5.38x39 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 181 | V | 5.39x40 | CCR6 | 6WWZ | Rhodopsin | 4ZWJ |
| TM5 | 182 | Q | 5.40x41 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM5 | 183 | A | 5.41x42 | CCR6 | 6WWZ | α2B-adrenoceptor | 6K41 |
| TM5 | 184 | A | 5.42x43 | CCR6 | 6WWZ | CysLT2 receptor | 6RZ6 |
| TM5 | 185 | L | 5.43x44 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 186 | I | 5.44x45 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM5 | 187 | M | 5.45x46 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM5 | 188 | G | 5.46x461 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 189 | V | 5.47x47 | CCR6 | 6WWZ | CB1 receptor | 5XRA |
| TM5 | 190 | L | 5.48x48 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM5 | 191 | T | 5.49x49 | CCR6 | 6WWZ | 5-HT2B receptor | 5TUD |
| TM5 | 192 | P | 5.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 193 | V | 5.51x51 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM5 | 194 | M | 5.52x52 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 195 | T | 5.53x53 | CCR6 | 6WWZ | C5a1 receptor | 5O9H |
| TM5 | 196 | L | 5.54x54 | CCR6 | 6WWZ | 5-HT1B receptor | 6G79 |
| TM5 | 197 | S | 5.55x55 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM5 | 198 | S | 5.56x56 | CCR6 | 6WWZ | EP3 receptor | 6M9T |
| TM5 | 199 | L | 5.57x57 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM5 | 200 | T | 5.58x58 | CCR6 | 6WWZ | GPR52 | 6LI3 |
| TM5 | 201 | L | 5.59x59 | CCR6 | 6WWZ | α2B-adrenoceptor | 6K41 |
| TM5 | 202 | F | 5.60x60 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 203 | V | 5.61x61 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM5 | 204 | W | 5.62x62 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM5 | 205 | V | 5.63x63 | CCR6 | 6WWZ | 5-HT1B receptor | 6G79 |
| TM5 | 206 | R | 5.64x64 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM5 | 207 | R | 5.65x65 | CCR6 | 6WWZ | - | - |
| TM5 | 208 | S | 5.66x66 | CCR6 | 6WWZ | PAR1 | 3VW7 |
| TM5 | 209 | S | 5.67x67 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM5 | 210 | Q | 5.68x68 | CCR6 | 6WWZ | β2-adrenoceptor | 6OBA |
| ICL3 | 211 | Q | - | - | - | - | |
| ICL3 | 212 | W | CCR5 | 6MEO | - | - | |
| ICL3 | 213 | R | - | - | - | - | |
| TM6 | 214 | R | 6.28x28 | PAR2 | 5NDD | μ receptor | 6DDF |
| TM6 | 215 | Q | 6.29x29 | PAR2 | 5NDD | CXCR2 | 6LFO |
| TM6 | 216 | P | 6.30x30 | CCR6 | 6WWZ | - | - |
| TM6 | 217 | T | 6.31x31 | CCR6 | 6WWZ | EP3 receptor | 6M9T |
| TM6 | 218 | R | 6.32x32 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM6 | 219 | L | 6.33x33 | CCR6 | 6WWZ | CB1 receptor | 6N4B |
| TM6 | 220 | F | 6.34x34 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM6 | 221 | V | 6.35x35 | CCR6 | 6WWZ | MT1 receptor | 6ME2 |
| TM6 | 222 | V | 6.36x36 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 223 | V | 6.37x37 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM6 | 224 | L | 6.38x38 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM6 | 225 | A | 6.39x39 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 226 | S | 6.40x40 | CCR6 | 6WWZ | - | - |
| TM6 | 227 | V | 6.41x41 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 228 | L | 6.42x42 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 229 | V | 6.43x43 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 230 | F | 6.44x44 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 231 | L | 6.45x45 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 232 | I | 6.46x46 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM6 | 233 | C | 6.47x47 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 234 | S | 6.48x48 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM6 | 235 | L | 6.49x49 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM6 | 236 | P | 6.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 237 | L | 6.51x51 | CCR6 | 6WWZ | CB1 receptor | 6N4B |
| TM6 | 238 | S | 6.52x52 | CCR6 | 6WWZ | OX1 receptor | 6TO7 |
| TM6 | 239 | I | 6.53x53 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM6 | 240 | Y | 6.54x54 | CCR6 | 6WWZ | μ receptor | 5C1M |
| TM6 | 241 | W | 6.55x55 | CCR6 | 6WWZ | - | - |
| TM6 | 242 | F | 6.56x56 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM6 | 243 | V | 6.57x57 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 244 | L | 6.58x58 | CCR6 | 6WWZ | 5-HT2B receptor | 5TUD |
| TM6 | 245 | Y | 6.59x59 | CCR6 | 6WWZ | PAR2 | 5NDD |
| TM6 | 246 | W | 6.60x60 | CCR6 | 6WWZ | Y1 receptor | 5ZBH |
| TM6 | 247 | L | 6.61x61 | C5a1 receptor | 5O9H | C5a1 receptor | 5O9H |
| ECL3 | 248 | S | - | - | - | - | |
| ECL3 | 249 | L | A2A receptor | 3VG9 | - | - | |
| ECL3 | 250 | P | A2A receptor | 3VG9 | - | - | |
| ECL3 | 251 | P | A2A receptor | 3VG9 | - | - | |
| ECL3 | 252 | E | A2A receptor | 3VG9 | - | - | |
| ECL3 | 253 | M | - | - | - | - | |
| TM7 | 254 | Q | 7.31x30 | CCR6 | 6WWZ | μ receptor | 5C1M |
| TM7 | 255 | V | 7.32x31 | CCR6 | 6WWZ | δ receptor | 6PT2 |
| TM7 | 256 | L | 7.33x32 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM7 | 257 | C | 7.34x33 | CCR6 | 6WWZ | OX1 receptor | 4ZJ8 |
| TM7 | 258 | F | 7.35x34 | CCR6 | 6WWZ | CB1 receptor | 6N4B |
| TM7 | 259 | S | 7.36x35 | CCR6 | 6WWZ | D2 receptor | 6VMS |
| TM7 | 260 | L | 7.37x36 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM7 | 261 | S | 7.38x37 | CCR6 | 6WWZ | OX1 receptor | 6TO7 |
| TM7 | 262 | R | 7.39x38 | CCR6 | 6WWZ | P2Y1 receptor | 4XNW |
| TM7 | 263 | L | 7.40x39 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM7 | 264 | S | 7.41x40 | CCR6 | 6WWZ | - | - |
| TM7 | 265 | S | 7.42x41 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM7 | 266 | S | 7.43x42 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM7 | 267 | V | 7.44x43 | CCR6 | 6WWZ | NTS1 receptor | 6OSA |
| TM7 | 268 | S | 7.45x45 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM7 | 269 | S | 7.46x46 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM7 | 270 | S | 7.47x47 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM7 | 271 | A | 7.48x48 | CCR6 | 6WWZ | GPBA receptor | 7CFN |
| TM7 | 272 | N | 7.49x49 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 273 | P | 7.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 274 | V | 7.51x51 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 275 | I | 7.52x52 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM7 | 276 | Y | 7.53x53 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 277 | F | 7.54x54 | CCR6 | 6WWZ | P2Y1 receptor | 4XNW |
| TM7 | 278 | L | 7.55x55 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM7 | 279 | V | 7.56x56 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| H8 | 280 | G | 8.47x47 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| H8 | 281 | S | 8.48x48 | CCR6 | 6WWZ | GPR52 | 6LI1 |
| H8 | 282 | R | 8.49x49 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| H8 | 283 | R | 8.50x50 | CCR6 | 6WWZ | - | - |
| H8 | 284 | S | 8.51x51 | CCR6 | 6WWZ | LPA1 receptor | 4Z35 |
| H8 | 285 | H | 8.52x52 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| H8 | 286 | R | 8.53x53 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| H8 | 287 | L | 8.54x54 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| H8 | 288 | P | 8.55x55 | CCR6 | 6WWZ | - | - |
| H8 | 289 | T | 8.56x56 | CCR6 | 6WWZ | Rhodopsin | 4ZWJ |
| H8 | 290 | R | 8.57x57 | CCR6 | 6WWZ | - | - |
| H8 | 291 | S | 8.58x58 | CCR6 | 6WWZ | GPR52 | 6LI3 |
| H8 | 292 | L | 8.59x59 | CCR6 | 6WWZ | apelin receptor | 5VBL |
| H8 | 293 | G | 8.60x60 | CCR6 | 6WWZ | - | - |
| H8 | 294 | T | 8.61x61 | CCR6 | 6WWZ | - | - |
| H8 | 295 | V | 8.62x62 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| C-term | 296 | L | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| C-term | 297 | Q | - | - | - | - | |
| C-term | 298 | Q | - | - | - | - | |
| C-term | 299 | A | - | - | - | - | |
| C-term | 300 | L | - | - | - | - |