ADGRD1 homology model

PROTEIN CLASS

Class B2 (Adhesion)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active

VERSION

2021-06-10

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

CRF1 receptor (sequence similarity: 15%) PDB: 6PB0

TEMPLATES

6PB0 (CRF1 receptor)
4Z9G (CRF1 receptor)
4K5Y (CRF1 receptor)
6P9Y (PAC1 receptor)
7D77 (ADGRG3)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 78.9 4.7 16.4
Side-chains 24.4 29.8 45.8

Number of backbone templates: 5
Number of rotamer templates: 14

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 556 L - CRF1 receptor 6PB0 CRF1 receptor 6PB0
N-term 557 E - CRF1 receptor 6PB0 CRF1 receptor 6PB0
N-term 558 L - CRF1 receptor 6PB0 CRF1 receptor 6PB0
N-term 559 A - CRF1 receptor 6PB0 CRF1 receptor 6PB0
N-term 560 R - CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM1 561 G 1.34x34 CRF1 receptor 6PB0 - -
TM1 562 H 1.35x35 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM1 563 Q 1.36x36 CRF1 receptor 6PB0 - -
TM1 564 V 1.37x37 CRF1 receptor 6PB0 - -
TM1 565 A 1.38x38 CRF1 receptor 6PB0 - -
TM1 566 L 1.39x39 CRF1 receptor 6PB0 CT receptor 6NIY
TM1 567 S 1.40x40 CRF1 receptor 6PB0 - -
TM1 568 S 1.41x41 CRF1 receptor 6PB0 - -
TM1 569 I 1.42x42 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM1 570 S 1.43x43 CRF1 receptor 6PB0 ADGRG3 7D77
TM1 571 Y 1.44x44 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM1 572 V 1.45x45 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM1 573 G 1.46x46 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM1 574 C 1.47x47 CRF1 receptor 6PB0 ADGRG3 7D77
TM1 575 S 1.48x48 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM1 576 L 1.49x49 CRF1 receptor 6PB0 CT receptor 6NIY
TM1 577 S 1.50x50 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM1 578 V 1.51x51 CRF1 receptor 6PB0 CRF2 receptor 6PB1
TM1 579 L 1.52x52 CRF1 receptor 6PB0 - -
TM1 580 C 1.53x53 CRF1 receptor 6PB0 - -
TM1 581 L 1.54x54 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM1 582 V 1.55x55 CRF1 receptor 6PB0 CRF2 receptor 6PB1
TM1 583 A 1.56x56 CRF1 receptor 6PB0 CRF2 receptor 6PB1
TM1 584 T 1.57x57 CRF1 receptor 6PB0 ADGRG3 7D77
TM1 585 L 1.58x58 CRF1 receptor 6PB0 CT receptor 6NIY
TM1 586 V 1.59x59 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM1 587 T 1.60x60 CRF1 receptor 6PB0 - -
TM1 588 F 1.61x61 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM1 589 A 1.62x62 CRF1 receptor 6PB0 ADGRG3 7D77
TM1 590 V 1.63x63 CRF1 receptor 6PB0 - -
TM1 591 L 1.64x64 CRF1 receptor 6PB0 CRF1 receptor 6PB0
ICL1 592 S 12.48x48 - - - -
ICL1 593 S 12.49x49 - - - -
ICL1 594 V 12.50x50 - - - -
ICL1 595 S 12.51x51 - - - -
TM2 596 T 2.41x41 - - - -
TM2 597 I 2.42x42 - - - -
TM2 598 R 2.43x43 - - - -
TM2 599 N 2.44x44 CRF1 receptor 6PB0 - -
TM2 600 Q 2.45x45 CRF1 receptor 6PB0 CT receptor 6NIY
TM2 601 R 2.46x46 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM2 602 Y 2.47x47 CRF1 receptor 6PB0 - -
TM2 603 H 2.48x48 CRF1 receptor 6PB0 - -
TM2 604 I 2.49x49 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM2 605 H 2.50x50 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM2 606 A 2.51x51 CRF1 receptor 6PB0 glucagon receptor 6WPW
TM2 607 N 2.52x52 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM2 608 L 2.53x53 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM2 609 S 2.54x54 CRF1 receptor 6PB0 - -
TM2 610 F 2.55x55 CRF1 receptor 6PB0 calcitonin receptor-like receptor 6UVA
TM2 611 A 2.56x56 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM2 612 V 2.57x57 CRF1 receptor 6PB0 - -
TM2 613 L 2.58x58 CRF1 receptor 6PB0 - -
TM2 614 V 2.59x59 CRF1 receptor 6PB0 - -
TM2 615 A 2.60x60 CRF1 receptor 6PB0 - -
TM2 616 Q 2.61x61 CRF1 receptor 6PB0 - -
TM2 617 V 2.62x62 CRF1 receptor 6PB0 CRF2 receptor 6PB1
TM2 618 L 2.63x63 CRF1 receptor 6PB0 - -
TM2 619 L 2.64x64 CRF1 receptor 6PB0 - -
TM2 620 L 2.65x65 CRF1 receptor 6PB0 ADGRG3 7D77
TM2 621 I 2.66x66 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM2 622 S 2.67x67 CRF1 receptor 6PB0 - -
TM2 623 F 2.68x68 CRF1 receptor 6PB0 - -
TM2 624 R 2.69x69 CRF1 receptor 6PB0 - -
TM2 625 L 2.70x70 CRF1 receptor 6PB0 glucagon receptor 6WPW
ECL1 626 E - - - - -
ECL1 627 P - - - - -
ECL1 628 G - - - - -
ECL1 629 T - - - - -
TM3 630 T 3.27x27 CRF1 receptor 6PB0 GLP-2 receptor 7D68
TM3 631 P 3.28x28 CRF1 receptor 6PB0 - -
TM3 632 C 3.29x29 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM3 633 Q 3.30x30 CRF1 receptor 6PB0 - -
TM3 634 V 3.31x31 CRF1 receptor 6PB0 calcitonin receptor-like receptor 6UVA
TM3 635 M 3.32x32 CRF1 receptor 6PB0 - -
TM3 636 A 3.33x33 CRF1 receptor 6PB0 glucagon receptor 6WPW
TM3 637 V 3.34x34 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM3 638 L 3.35x35 CRF1 receptor 6PB0 secretin receptor 6WZG
TM3 639 L 3.36x36 CRF1 receptor 6PB0 GLP-2 receptor 7D68
TM3 640 H 3.37x37 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM3 641 Y 3.38x38 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM3 642 F 3.39x39 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM3 643 F 3.40x40 CRF1 receptor 6PB0 - -
TM3 644 L 3.41x41 CRF1 receptor 6PB0 ADGRG3 7D77
TM3 645 S 3.42x42 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM3 646 A 3.43x43 CRF1 receptor 6PB0 ADGRG3 7D77
TM3 647 F 3.44x44 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM3 648 A 3.45x45 CRF1 receptor 6PB0 - -
TM3 649 W 3.46x46 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM3 650 M 3.47x47 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM3 651 L 3.48x48 CRF1 receptor 6PB0 CT receptor 6NIY
TM3 652 V 3.49x49 CRF1 receptor 6PB0 CRF2 receptor 6PB1
TM3 653 E 3.50x50 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM3 654 G 3.51x51 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM3 655 L 3.52x52 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM3 656 H 3.53x53 CRF1 receptor 6PB0 ADGRG3 7D77
TM3 657 L 3.54x54 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM3 658 Y 3.55x55 CRF1 receptor 6PB0 ADGRG3 7D77
TM3 659 S 3.56x56 CRF1 receptor 6PB0 PTH1 receptor 6NBI
TM3 660 M 3.57x57 CRF1 receptor 6PB0 - -
TM3 661 V 3.58x58 CRF1 receptor 6PB0 - -
TM3 662 I 3.59x59 CRF1 receptor 6PB0 - -
TM3 663 K 3.60x60 CRF1 receptor 6PB0 PTH1 receptor 6FJ3
ICL2 664 V - - - - -
ICL2 665 F - - - - -
ICL2 666 G - - - - -
ICL2 667 S - - - - -
ICL2 668 E - - - - -
ICL2 669 D - - - - -
TM4 670 S 4.40x41 CRF1 receptor 4Z9G - -
TM4 671 K 4.41x42 CRF1 receptor 4Z9G - -
TM4 672 H 4.42x43 CRF1 receptor 6PB0 - -
TM4 673 R 4.43x44 CRF1 receptor 6PB0 CT receptor 6NIY
TM4 674 Y 4.44x45 CRF1 receptor 6PB0 - -
TM4 675 Y 4.45x46 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM4 676 Y 4.46x47 CRF1 receptor 6PB0 CT receptor 6NIY
TM4 677 G 4.47x48 CRF1 receptor 6PB0 glucagon receptor 6WPW
TM4 678 M 4.48x49 CRF1 receptor 6PB0 - -
TM4 679 G 4.49x491 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM4 680 W 4.50x50 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM4 681 G 4.51x51 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM4 682 F 4.52x52 CRF1 receptor 6PB0 CT receptor 6NIY
TM4 683 P 4.53x53 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM4 684 L 4.54x54 CRF1 receptor 6PB0 CT receptor 6NIY
TM4 685 L 4.55x55 CRF1 receptor 6PB0 ADGRG3 7D77
TM4 686 I 4.56x56 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM4 687 C 4.57x57 CRF1 receptor 6PB0 - -
TM4 688 I 4.58x58 CRF1 receptor 6PB0 ADGRG3 7D77
TM4 689 I 4.59x59 CRF1 receptor 6PB0 CT receptor 6NIY
TM4 690 S 4.60x60 CRF1 receptor 6PB0 - -
TM4 691 L 4.61x61 CRF1 receptor 6PB0 - -
TM4 692 S 4.62x62 CRF1 receptor 6PB0 ADGRG3 7D77
TM4 693 F 4.63x63 CRF1 receptor 6PB0 - -
TM4 694 A 4.64x64 CRF1 receptor 6PB0 - -
ECL2 695 M - - - - -
ECL2 696 D - - - - -
ECL2 697 S - - - - -
ECL2 698 Y - - - - -
ECL2 699 G - - - - -
ECL2 700 T - - - - -
ECL2 701 S - - - - -
ECL2 702 N - - - - -
ECL2 703 N - - - - -
ECL2 704 C 45.50x50 CRF1 receptor 6PB0 CRF1 receptor 6PB0
ECL2 705 W 45.51x51 CRF1 receptor 6PB0 CRF1 receptor 6PB0
ECL2 706 L 45.52x52 CRF1 receptor 6PB0 CT receptor 6NIY
ECL2 707 S - - - - -
ECL2 708 L - PAC1 receptor 6P9Y - -
ECL2 709 A - - - - -
TM5 710 S 5.33x33 PAC1 receptor 6P9Y PAC1 receptor 6P9Y
TM5 711 G 5.34x34 PAC1 receptor 6P9Y - -
TM5 712 A 5.35x35 PAC1 receptor 6P9Y PAC1 receptor 6P9Y
TM5 713 I 5.36x36 CRF1 receptor 6PB0 secretin receptor 6WZG
TM5 714 W 5.37x37 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM5 715 A 5.38x38 CRF1 receptor 6PB0 - -
TM5 716 F 5.39x39 CRF1 receptor 6PB0 - -
TM5 717 V 5.40x40 CRF1 receptor 6PB0 - -
TM5 718 A 5.41x41 CRF1 receptor 6PB0 - -
TM5 719 P 5.42x42 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM5 720 A 5.43x43 CRF1 receptor 6PB0 - -
TM5 721 L 5.44x44 CRF1 receptor 6PB0 ADGRG3 7D77
TM5 722 F 5.45x45 CRF1 receptor 6PB0 GLP-1 receptor 5VAI
TM5 723 V 5.46x46 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM5 724 I 5.47x47 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM5 725 V 5.48x48 CRF1 receptor 6PB0 CT receptor 6NIY
TM5 726 V 5.49x49 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM5 727 N 5.50x50 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM5 728 I 5.51x51 CRF1 receptor 6PB0 - -
TM5 729 G 5.52x52 CRF1 receptor 6PB0 GHRH receptor 7CZ5
TM5 730 I 5.53x53 CRF1 receptor 6PB0 glucagon receptor 6WPW
TM5 731 L 5.54x54 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM5 732 I 5.55x55 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM5 733 A 5.56x56 CRF1 receptor 6PB0 - -
TM5 734 V 5.57x57 CRF1 receptor 6PB0 ADGRG3 7D77
TM5 735 T 5.58x58 CRF1 receptor 6PB0 - -
TM5 736 R 5.59x59 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM5 737 V 5.60x60 CRF1 receptor 6PB0 CT receptor 6NIY
TM5 738 I 5.61x61 CRF1 receptor 6PB0 ADGRG3 7D77
TM5 739 S 5.62x62 CRF1 receptor 6PB0 - -
TM5 740 Q 5.63x63 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM5 741 I 5.64x64 CRF1 receptor 6PB0 - -
TM5 742 S 5.65x65 CRF1 receptor 6PB0 ADGRG3 7D77
ICL3 743 A - - - - -
ICL3 744 D - - - - -
ICL3 745 N - - - - -
ICL3 746 Y - - - - -
ICL3 747 K - - - - -
ICL3 749 H - - - - -
ICL3 750 G - - - - -
ICL3 751 D - - - - -
ICL3 752 P - - - - -
ICL3 753 S - - - - -
TM6 754 A 6.34x34 CRF1 receptor 6PB0 - -
TM6 755 F 6.35x35 CRF1 receptor 6PB0 - -
TM6 756 K 6.36x36 CRF1 receptor 6PB0 secretin receptor 6WZG
TM6 757 L 6.37x37 CRF1 receptor 6PB0 - -
TM6 758 T 6.38x38 CRF1 receptor 6PB0 - -
TM6 759 A 6.39x39 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
TM6 760 K 6.40x40 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM6 761 A 6.41x41 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM6 762 V 6.42x42 CRF1 receptor 6PB0 - -
TM6 763 A 6.43x43 CRF1 receptor 6PB0 - -
TM6 764 V 6.44x44 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM6 765 L 6.45x45 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM6 766 L 6.46x46 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM6 767 P 6.47x47 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM6 768 I 6.48x48 CRF1 receptor 6PB0 - -
TM6 769 L 6.49x49 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM6 770 G 6.50x50 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM6 771 T 6.51x51 CRF1 receptor 6PB0 GLP-1 receptor 5VAI
TM6 772 S 6.52x52 CRF1 receptor 6PB0 - -
TM6 773 W 6.53x53 CRF1 receptor 6PB0 ADGRG3 7D77
TM6 774 V 6.54x54 CRF1 receptor 6PB0 CT receptor 6NIY
TM6 775 F 6.55x55 CRF1 receptor 6PB0 - -
TM6 776 G 6.56x56 CRF1 receptor 4Z9G - -
TM6 777 V 6.57x57 CRF1 receptor 4Z9G - -
TM6 778 L 6.58x58 CRF1 receptor 4Z9G - -
ECL3 779 A - - - - -
ECL3 780 V - CRF1 receptor 4K5Y - -
ECL3 781 N - CRF1 receptor 4K5Y - -
ECL3 782 G - CRF1 receptor 4K5Y - -
ECL3 783 C - - - - -
TM7 784 A 7.35x34 CRF1 receptor 6PB0 - -
TM7 785 V 7.36x35 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM7 786 V 7.37x36 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM7 787 F 7.38x37 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM7 788 Q 7.39x38 CRF1 receptor 6PB0 - -
TM7 789 Y 7.40x39 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM7 790 M 7.41x40 CRF1 receptor 6PB0 - -
TM7 791 F 7.42x41 CRF1 receptor 6PB0 ADGRG3 7D77
TM7 792 A 7.43x42 CRF1 receptor 6PB0 ADGRG3 7D77
TM7 793 T 7.44x43 CRF1 receptor 6PB0 GLP-2 receptor 7D68
TM7 794 L 7.45x44 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM7 795 N 7.46x45 CRF1 receptor 6PB0 ADGRG3 7D77
TM7 796 S 7.47x46 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM7 797 L 7.48x47 CRF1 receptor 6PB0 ADGRG3 7D77
TM7 798 Q 7.49x49 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM7 799 G 7.50x50 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM7 800 L 7.51x51 CRF1 receptor 6PB0 calcitonin receptor-like receptor 6UVA
TM7 801 F 7.52x52 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM7 802 I 7.53x53 CRF1 receptor 6PB0 ADGRG3 7D77
TM7 803 F 7.54x54 CRF1 receptor 6PB0 - -
TM7 804 L 7.55x55 CRF1 receptor 6PB0 GLP-2 receptor 7D68
TM7 805 F 7.56x56 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM7 806 H 7.57x57 CRF1 receptor 6PB0 - -
TM7 807 C 7.58x58 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM7 808 L 7.59x59 CRF1 receptor 6PB0 - -
TM7 809 L 7.60x60 CRF1 receptor 6PB0 CRF1 receptor 6PB0
TM7 810 N 7.61x61 ADGRG3 7D77 - -
H8 811 S 8.48x48 CRF1 receptor 6PB0 CRF1 receptor 6PB0
H8 812 E 8.49x49 CRF1 receptor 6PB0 CRF1 receptor 6PB0
H8 813 V 8.50x50 CRF1 receptor 6PB0 CRF1 receptor 6PB0
H8 814 R 8.51x51 CRF1 receptor 6PB0 CRF1 receptor 6PB0
H8 815 A 8.52x52 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
H8 816 A 8.53x53 CRF1 receptor 6PB0 CRF1 receptor 6PB0
H8 817 F 8.54x54 CRF1 receptor 6PB0 GLP-1 receptor 5VAI
H8 818 K 8.55x55 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
H8 819 H 8.56x56 CRF1 receptor 6PB0 - -
H8 820 K 8.57x57 CRF1 receptor 6PB0 PAC1 receptor 6P9Y
H8 821 T 8.58x58 CRF1 receptor 6PB0 - -
H8 822 K 8.59x59 CRF1 receptor 6PB0 - -
H8 823 V 8.60x60 CRF1 receptor 6PB0 - -
H8 824 W 8.61x61 CRF1 receptor 6PB0 CRF1 receptor 6PB0
H8 825 S 8.62x62 CRF1 receptor 6PB0 - -
H8 826 L 8.63x63 CRF1 receptor 6PB0 secretin receptor 6WI9
C-term 827 T - - - - -
C-term 828 S - - - - -
C-term 829 S - - - - -
C-term 830 S - - - - -
C-term 831 A - - - - -