SST4 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active

VERSION

2021-11-02

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

κ receptor (sequence similarity: 47%) PDB: 6B73

TEMPLATES

6B73 (κ receptor)
4DJH (κ receptor)
3ODU (CXCR4)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 82.6 10.2 7.2
Side-chains 35.8 50.2 14.0

Number of backbone templates: 3
Number of rotamer templates: 41

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
TM1 40 G 1.25x25 - - - -
TM1 41 D 1.26x26 - - - -
TM1 42 A 1.27x27 κ receptor 6B73 κ receptor 6B73
TM1 43 R 1.28x28 κ receptor 6B73 κ receptor 6B73
TM1 44 A 1.29x29 κ receptor 6B73 κ receptor 6B73
TM1 45 A 1.30x30 κ receptor 6B73 κ receptor 6B73
TM1 46 G 1.31x31 κ receptor 6B73 A2A receptor 5WF5
TM1 47 M 1.32x32 κ receptor 6B73 M4 receptor 6KP6
TM1 48 V 1.33x33 κ receptor 6B73 κ receptor 6B73
TM1 49 A 1.34x34 κ receptor 6B73 δ receptor 6PT2
TM1 50 I 1.35x35 κ receptor 6B73 κ receptor 6B73
TM1 51 Q 1.36x36 κ receptor 6B73 - -
TM1 52 C 1.37x37 κ receptor 6B73 D1 receptor 7JVQ
TM1 53 I 1.38x38 κ receptor 6B73 CXCR2 6LFO
TM1 54 Y 1.39x39 κ receptor 6B73 κ receptor 6B73
TM1 55 A 1.40x40 κ receptor 6B73 CXCR2 6LFO
TM1 56 L 1.41x41 κ receptor 6B73 CXCR2 6LFO
TM1 57 V 1.42x42 κ receptor 6B73 κ receptor 6B73
TM1 58 C 1.43x43 κ receptor 6B73 μ receptor 5C1M
TM1 59 L 1.44x44 κ receptor 6B73 CXCR2 6LFO
TM1 60 V 1.45x45 κ receptor 6B73 κ receptor 6B73
TM1 61 G 1.46x46 κ receptor 6B73 κ receptor 6B73
TM1 62 L 1.47x47 κ receptor 6B73 κ receptor 6B73
TM1 63 V 1.48x48 κ receptor 6B73 κ receptor 6B73
TM1 64 G 1.49x49 κ receptor 6B73 κ receptor 6B73
TM1 65 N 1.50x50 κ receptor 6B73 κ receptor 6B73
TM1 66 A 1.51x51 κ receptor 6B73 α2B-adrenoceptor 6K42
TM1 67 L 1.52x52 κ receptor 6B73 κ receptor 6B73
TM1 68 V 1.53x53 κ receptor 6B73 κ receptor 6B73
TM1 69 I 1.54x54 κ receptor 6B73 CCK1 receptor 7EZM
TM1 70 F 1.55x55 κ receptor 6B73 κ receptor 6B73
TM1 71 V 1.56x56 κ receptor 6B73 κ receptor 6B73
TM1 72 I 1.57x57 κ receptor 6B73 κ receptor 6B73
TM1 73 L 1.58x58 κ receptor 6B73 CXCR2 6LFO
TM1 74 R 1.59x59 κ receptor 6B73 μ receptor 5C1M
TM1 75 Y 1.60x60 κ receptor 6B73 κ receptor 6B73
ICL1 76 A 12.48x48 - - - -
ICL1 77 K 12.49x49 κ receptor 4DJH 5-HT2C receptor 6BQG
ICL1 78 M 12.50x50 κ receptor 4DJH κ receptor 4DJH
ICL1 79 K 12.51x51 - - - -
TM2 80 T 2.37x37 κ receptor 6B73 κ receptor 6B73
TM2 81 A 2.38x38 κ receptor 6B73 κ receptor 6B73
TM2 82 T 2.39x39 κ receptor 6B73 κ receptor 6B73
TM2 83 N 2.40x40 κ receptor 6B73 κ receptor 6B73
TM2 84 I 2.41x41 κ receptor 6B73 κ receptor 6B73
TM2 85 Y 2.42x42 κ receptor 6B73 κ receptor 6B73
TM2 86 L 2.43x43 κ receptor 6B73 AT1 receptor 6DO1
TM2 87 L 2.44x44 κ receptor 6B73 AT1 receptor 6DO1
TM2 88 N 2.45x45 κ receptor 6B73 κ receptor 6B73
TM2 89 L 2.46x46 κ receptor 6B73 κ receptor 6B73
TM2 90 A 2.47x47 κ receptor 6B73 κ receptor 6B73
TM2 91 V 2.48x48 κ receptor 6B73 CCK1 receptor 7EZM
TM2 92 A 2.49x49 κ receptor 6B73 κ receptor 6B73
TM2 93 D 2.50x50 κ receptor 6B73 κ receptor 6B73
TM2 94 E 2.51x51 κ receptor 6B73 - -
TM2 95 L 2.52x52 κ receptor 6B73 κ receptor 6B73
TM2 96 F 2.53x53 κ receptor 6B73 AT1 receptor 6DO1
TM2 97 M 2.54x54 κ receptor 6B73 - -
TM2 98 L 2.55x55 κ receptor 6B73 AT1 receptor 6DO1
TM2 99 S 2.56x56 κ receptor 6B73 M2 receptor 4MQT
TM2 100 V 2.57x57 κ receptor 6B73 CCR5 7O7F
TM2 101 P 2.58x58 κ receptor 6B73 κ receptor 6B73
TM2 102 F 2.59x59 κ receptor 6B73 κ receptor 6B73
TM2 103 V 2.60x60 κ receptor 6B73 MT1 receptor 7DB6
TM2 104 A 2.61x61 κ receptor 6B73 AT1 receptor 6DO1
TM2 105 S 2.62x62 κ receptor 6B73 LH receptor 7FIG
TM2 106 S 2.63x63 κ receptor 6B73 CXCR2 6LFO
TM2 107 A 2.64x64 κ receptor 6B73 CCR5 7O7F
TM2 108 A 2.65x65 κ receptor 6B73 AT1 receptor 6DO1
TM2 109 L 2.66x66 κ receptor 6B73 CCK1 receptor 7EZM
ECL1 110 R - - - - -
ECL1 111 H 23.49x49 κ receptor 4DJH M1 receptor 6OIJ
ECL1 112 W 23.50x50 κ receptor 4DJH κ receptor 4DJH
ECL1 113 P 23.51x51 κ receptor 4DJH κ receptor 4DJH
ECL1 114 F 23.52x52 - - - -
TM3 115 G 3.21x21 κ receptor 6B73 κ receptor 6B73
TM3 116 S 3.22x22 κ receptor 6B73 CCK1 receptor 7EZM
TM3 117 V 3.23x23 κ receptor 6B73 κ receptor 6B73
TM3 118 L 3.24x24 κ receptor 6B73 κ receptor 6B73
TM3 119 C 3.25x25 κ receptor 6B73 κ receptor 6B73
TM3 120 R 3.26x26 κ receptor 6B73 NTS1 receptor 6OSA
TM3 121 A 3.27x27 κ receptor 6B73 δ receptor 6PT2
TM3 122 V 3.28x28 κ receptor 6B73 κ receptor 6B73
TM3 123 L 3.29x29 κ receptor 6B73 κ receptor 6B73
TM3 124 S 3.30x30 κ receptor 6B73 κ receptor 6B73
TM3 125 V 3.31x31 κ receptor 6B73 β1-adrenoceptor 7BU7
TM3 126 D 3.32x32 κ receptor 6B73 κ receptor 6B73
TM3 127 G 3.33x33 κ receptor 6B73 CCK1 receptor 7EZM
TM3 128 L 3.34x34 κ receptor 6B73 β2-adrenoceptor 3SN6
TM3 129 N 3.35x35 κ receptor 6B73 κ receptor 6B73
TM3 130 M 3.36x36 κ receptor 6B73 κ receptor 6B73
TM3 131 F 3.37x37 κ receptor 6B73 κ receptor 6B73
TM3 132 T 3.38x38 κ receptor 6B73 κ receptor 6B73
TM3 133 S 3.39x39 κ receptor 6B73 κ receptor 6B73
TM3 134 V 3.40x40 κ receptor 6B73 AT1 receptor 6DO1
TM3 135 F 3.41x41 κ receptor 6B73 κ receptor 6B73
TM3 136 C 3.42x42 κ receptor 6B73 GPR52 6LI3
TM3 137 L 3.43x43 κ receptor 6B73 κ receptor 6B73
TM3 138 T 3.44x44 κ receptor 6B73 κ receptor 6B73
TM3 139 V 3.45x45 κ receptor 6B73 β2-adrenoceptor 3SN6
TM3 140 L 3.46x46 κ receptor 6B73 AT1 receptor 6DO1
TM3 141 S 3.47x47 κ receptor 6B73 κ receptor 6B73
TM3 142 V 3.48x48 κ receptor 6B73 κ receptor 6B73
TM3 143 D 3.49x49 κ receptor 6B73 κ receptor 6B73
TM3 144 R 3.50x50 κ receptor 6B73 κ receptor 6B73
TM3 145 Y 3.51x51 κ receptor 6B73 κ receptor 6B73
TM3 146 V 3.52x52 κ receptor 6B73 5-HT2C receptor 6BQG
TM3 147 A 3.53x53 κ receptor 6B73 κ receptor 6B73
TM3 148 V 3.54x54 κ receptor 6B73 κ receptor 6B73
TM3 149 V 3.55x55 κ receptor 6B73 AT1 receptor 6DO1
TM3 150 H 3.56x56 κ receptor 6B73 κ receptor 6B73
ICL2 151 P 34.50x50 κ receptor 6B73 κ receptor 6B73
ICL2 152 L 34.51x51 κ receptor 6B73 CCK1 receptor 7EZM
ICL2 153 R 34.52x52 κ receptor 6B73 CXCR2 6LFO
ICL2 154 A 34.53x53 κ receptor 6B73 κ receptor 6B73
ICL2 155 A 34.54x54 κ receptor 6B73 5-HT1F receptor 7EXD
ICL2 156 T 34.55x55 κ receptor 6B73 CXCR2 6LFO
ICL2 157 Y 34.56x56 κ receptor 6B73 EP4 receptor 7D7M
ICL2 158 R 34.57x57 κ receptor 6B73 κ receptor 6B73
TM4 159 R 4.38x38 κ receptor 6B73 LH receptor 7FIG
TM4 160 P 4.39x39 κ receptor 6B73 κ receptor 6B73
TM4 161 S 4.40x40 κ receptor 6B73 CCK1 receptor 7EZM
TM4 162 V 4.41x41 κ receptor 6B73 AT1 receptor 6DO1
TM4 163 A 4.42x42 κ receptor 6B73 κ receptor 6B73
TM4 164 K 4.43x43 κ receptor 6B73 κ receptor 6B73
TM4 165 L 4.44x44 κ receptor 6B73 δ receptor 6PT2
TM4 166 I 4.45x45 κ receptor 6B73 κ receptor 6B73
TM4 167 N 4.46x46 κ receptor 6B73 κ receptor 6B73
TM4 168 L 4.47x47 κ receptor 6B73 CXCR2 6LFO
TM4 169 G 4.48x48 κ receptor 6B73 FPR2/ALX 6OMM
TM4 170 V 4.49x49 κ receptor 6B73 β2-adrenoceptor 3SN6
TM4 171 W 4.50x50 κ receptor 6B73 κ receptor 6B73
TM4 172 L 4.51x51 κ receptor 6B73 κ receptor 6B73
TM4 173 A 4.52x52 κ receptor 6B73 NTS1 receptor 6OSA
TM4 174 S 4.53x53 κ receptor 6B73 κ receptor 6B73
TM4 175 L 4.54x54 κ receptor 6B73 CXCR2 6LFO
TM4 176 L 4.55x55 κ receptor 6B73 AT1 receptor 6DO1
TM4 177 V 4.56x56 κ receptor 6B73 κ receptor 6B73
TM4 178 T 4.57x57 CXCR4 3ODU FPR2/ALX 6OMM
TM4 179 L 4.58x59 CXCR4 3ODU AT1 receptor 6DO1
TM4 180 P 4.59x60 κ receptor 6B73 AT1 receptor 6DO1
TM4 181 I 4.60x61 κ receptor 6B73 κ receptor 6B73
TM4 182 A 4.61x62 κ receptor 6B73 OX2 receptor 7L1V
TM4 183 I 4.62x63 κ receptor 6B73 AT1 receptor 6DO1
TM4 184 F 4.63x64 κ receptor 6B73 CCR5 7F1S
TM4 185 A 4.64x65 CXCR4 3ODU CXCR4 3ODU
ECL2 186 D - κ receptor 6B73 - -
ECL2 187 T - κ receptor 6B73 κ receptor 6B73
ECL2 188 R - κ receptor 6B73 - -
ECL2 189 P - κ receptor 6B73 - -
ECL2 190 A - κ receptor 6B73 - -
ECL2 191 R - - - - -
ECL2 192 G - - - - -
ECL2 193 G - - - - -
ECL2 194 Q - κ receptor 6B73 - -
ECL2 195 A - κ receptor 6B73 - -
ECL2 196 V - κ receptor 6B73 - -
ECL2 197 A - κ receptor 6B73 - -
ECL2 198 C 45.50x50 κ receptor 6B73 κ receptor 6B73
ECL2 199 N 45.51x51 κ receptor 6B73 - -
ECL2 200 L 45.52x52 κ receptor 6B73 κ receptor 6B73
ECL2 201 Q - - - - -
ECL2 202 W - - - - -
TM5 203 P 5.30x31 κ receptor 4DJH - -
TM5 204 H 5.31x32 κ receptor 4DJH - -
TM5 205 P 5.32x33 κ receptor 4DJH succinate receptor 6RNK
TM5 206 A 5.33x34 κ receptor 6B73 NTS1 receptor 6OSA
TM5 207 W 5.34x35 κ receptor 6B73 κ receptor 6B73
TM5 208 S 5.35x36 κ receptor 6B73 AT2 receptor 5UNG
TM5 209 A 5.36x37 κ receptor 6B73 AT2 receptor 5UNG
TM5 210 V 5.37x38 κ receptor 6B73 δ receptor 6PT2
TM5 211 F 5.38x39 κ receptor 6B73 5-HT2B receptor 5TUD
TM5 212 V 5.39x40 κ receptor 6B73 D2 receptor 7JVR
TM5 213 V 5.40x41 κ receptor 6B73 H1 receptor 7DFL
TM5 214 Y 5.41x42 κ receptor 6B73 D2 receptor 7JVR
TM5 215 T 5.42x43 κ receptor 6B73 H1 receptor 7DFL
TM5 216 F 5.43x44 κ receptor 6B73 κ receptor 6B73
TM5 217 L 5.44x45 κ receptor 6B73 δ receptor 6PT2
TM5 218 L 5.45x46 κ receptor 6B73 AT1 receptor 6DO1
TM5 219 G 5.46x461 κ receptor 6B73 AT1 receptor 6DO1
TM5 220 F 5.47x47 κ receptor 6B73 κ receptor 6B73
TM5 221 L 5.48x48 κ receptor 6B73 AT1 receptor 6DO1
TM5 222 L 5.49x49 κ receptor 6B73 CCR5 7O7F
TM5 223 P 5.50x50 κ receptor 6B73 κ receptor 6B73
TM5 224 V 5.51x51 κ receptor 6B73 κ receptor 6B73
TM5 225 L 5.52x52 κ receptor 6B73 κ receptor 6B73
TM5 226 A 5.53x53 κ receptor 6B73 EP4 receptor 7D7M
TM5 227 I 5.54x54 κ receptor 6B73 κ receptor 6B73
TM5 228 G 5.55x55 κ receptor 6B73 NK1 receptor 6HLP
TM5 229 L 5.56x56 κ receptor 6B73 OX2 receptor 7L1V
TM5 230 C 5.57x57 κ receptor 6B73 κ receptor 6B73
TM5 231 Y 5.58x58 κ receptor 6B73 κ receptor 6B73
TM5 232 L 5.59x59 κ receptor 6B73 β1-adrenoceptor 7BU7
TM5 233 L 5.60x60 κ receptor 6B73 κ receptor 6B73
TM5 234 I 5.61x61 κ receptor 6B73 AT1 receptor 6DO1
TM5 235 V 5.62x62 κ receptor 6B73 CCR6 6WWZ
TM5 236 G 5.63x63 κ receptor 6B73 EP4 receptor 7D7M
TM5 237 K 5.64x64 κ receptor 6B73 FPR2/ALX 6OMM
TM5 238 M 5.65x65 κ receptor 6B73 ETB receptor 5X93
TM5 239 R 5.66x66 κ receptor 6B73 δ receptor 6PT2
TM5 240 A 5.67x67 κ receptor 6B73 V2 receptor 7KH0
TM5 241 V 5.68x68 κ receptor 4DJH κ receptor 4DJH
ICL3 242 A - κ receptor 6B73 - -
ICL3 243 L - - - - -
ICL3 244 R - - - - -
ICL3 245 A - - - - -
ICL3 246 G - - - - -
TM6 247 W 6.23x23 κ receptor 6B73 - -
TM6 248 Q 6.24x24 κ receptor 6B73 A1 receptor 6D9H
TM6 249 Q 6.25x25 κ receptor 6B73 5-HT2B receptor 5TUD
TM6 250 R 6.26x26 κ receptor 6B73 NTS1 receptor 6OSA
TM6 251 R 6.27x27 κ receptor 6B73 AT2 receptor 5UNG
TM6 252 R 6.28x28 κ receptor 6B73 μ receptor 6DDF
TM6 253 S 6.29x29 κ receptor 6B73 δ receptor 6PT2
TM6 254 E 6.30x30 κ receptor 6B73 β2-adrenoceptor 3SN6
TM6 255 K 6.31x31 κ receptor 6B73 CCK1 receptor 7EZM
TM6 256 K 6.32x32 κ receptor 6B73 β1-adrenoceptor 7BU7
TM6 257 I 6.33x33 κ receptor 6B73 κ receptor 6B73
TM6 258 T 6.34x34 κ receptor 6B73 κ receptor 6B73
TM6 259 R 6.35x35 κ receptor 6B73 κ receptor 6B73
TM6 260 L 6.36x36 κ receptor 6B73 κ receptor 6B73
TM6 261 V 6.37x37 κ receptor 6B73 κ receptor 6B73
TM6 262 L 6.38x38 κ receptor 6B73 κ receptor 6B73
TM6 263 M 6.39x39 κ receptor 6B73 CysLT1 receptor 6RZ4
TM6 264 V 6.40x40 κ receptor 6B73 κ receptor 6B73
TM6 265 V 6.41x41 κ receptor 6B73 κ receptor 6B73
TM6 266 V 6.42x42 κ receptor 6B73 δ receptor 6PT2
TM6 267 V 6.43x43 κ receptor 6B73 κ receptor 6B73
TM6 268 F 6.44x44 κ receptor 6B73 κ receptor 6B73
TM6 269 V 6.45x45 κ receptor 6B73 κ receptor 6B73
TM6 270 L 6.46x46 κ receptor 6B73 CXCR2 6LFO
TM6 271 C 6.47x47 κ receptor 6B73 κ receptor 6B73
TM6 272 W 6.48x48 κ receptor 6B73 κ receptor 6B73
TM6 273 M 6.49x49 κ receptor 6B73 CCK1 receptor 7EZM
TM6 274 P 6.50x50 κ receptor 6B73 κ receptor 6B73
TM6 275 F 6.51x51 κ receptor 6B73 β2-adrenoceptor 3SN6
TM6 276 Y 6.52x52 κ receptor 6B73 CXCR4 3ODU
TM6 277 V 6.53x53 κ receptor 6B73 AT2 receptor 5UNG
TM6 278 V 6.54x54 κ receptor 6B73 CXCR2 6LFO
TM6 279 Q 6.55x55 κ receptor 6B73 V2 receptor 7KH0
TM6 280 L 6.56x56 κ receptor 6B73 κ receptor 6B73
TM6 281 L 6.57x57 κ receptor 6B73 AT1 receptor 6DO1
TM6 282 N 6.58x58 κ receptor 6B73 CCR5 7O7F
TM6 283 L 6.59x59 κ receptor 6B73 A1 receptor 6D9H
TM6 284 F 6.60x60 κ receptor 6B73 CCR5 7O7F
TM6 285 V 6.61x61 κ receptor 6B73 δ receptor 6PT2
ECL3 286 T - - - - -
ECL3 287 S - κ receptor 6B73 - -
ECL3 288 L - κ receptor 6B73 - -
ECL3 289 D - κ receptor 6B73 - -
TM7 290 A 7.32x31 κ receptor 6B73 OT receptor 6TPK
TM7 291 T 7.33x32 κ receptor 6B73 AT1 receptor 6DO1
TM7 292 V 7.34x33 κ receptor 6B73 β2-adrenoceptor 3SN6
TM7 293 N 7.35x34 κ receptor 6B73 ghrelin receptor 6KO5
TM7 294 H 7.36x35 κ receptor 6B73 μ receptor 5C1M
TM7 295 V 7.37x36 κ receptor 6B73 CCR5 7O7F
TM7 296 S 7.38x37 κ receptor 6B73 OX2 receptor 7L1V
TM7 297 L 7.39x38 κ receptor 6B73 CCK1 receptor 7EZM
TM7 298 I 7.40x39 κ receptor 6B73 CXCR2 6LFO
TM7 299 L 7.41x40 κ receptor 6B73 κ receptor 6B73
TM7 300 S 7.42x41 κ receptor 6B73 CCK1 receptor 7EZM
TM7 301 Y 7.43x42 κ receptor 6B73 κ receptor 6B73
TM7 302 A 7.44x43 κ receptor 6B73 β1-adrenoceptor 7BU7
TM7 303 N 7.45x45 κ receptor 6B73 κ receptor 6B73
TM7 304 S 7.46x46 κ receptor 6B73 κ receptor 6B73
TM7 305 C 7.47x47 κ receptor 6B73 μ receptor 5C1M
TM7 306 A 7.48x48 κ receptor 6B73 OX2 receptor 7L1V
TM7 307 N 7.49x49 κ receptor 6B73 κ receptor 6B73
TM7 308 P 7.50x50 κ receptor 6B73 κ receptor 6B73
TM7 309 I 7.51x51 κ receptor 6B73 CCK1 receptor 7EZM
TM7 310 L 7.52x52 κ receptor 4DJH κ receptor 4DJH
TM7 311 Y 7.53x53 κ receptor 4DJH κ receptor 4DJH
TM7 312 G 7.54x54 κ receptor 4DJH AT1 receptor 6DO1
TM7 313 F 7.55x55 κ receptor 4DJH κ receptor 4DJH
TM7 314 L 7.56x56 κ receptor 4DJH κ receptor 4DJH
H8 315 S 8.47x47 κ receptor 4DJH β2-adrenoceptor 3SN6
H8 316 D 8.48x48 κ receptor 4DJH NK1 receptor 6HLP
H8 317 N 8.49x49 κ receptor 4DJH κ receptor 4DJH
H8 318 F 8.50x50 κ receptor 4DJH κ receptor 4DJH
H8 319 R 8.51x51 κ receptor 4DJH CXCR2 6LFO
H8 320 R 8.52x52 κ receptor 4DJH κ receptor 4DJH
H8 321 F 8.53x53 κ receptor 4DJH - -
H8 322 F 8.54x54 κ receptor 4DJH κ receptor 4DJH
H8 323 Q 8.55x55 κ receptor 4DJH β2-adrenoceptor 3SN6
H8 324 R 8.56x56 κ receptor 4DJH 5-HT2B receptor 5TUD
H8 325 V 8.57x57 κ receptor 4DJH AT2 receptor 5UNG
H8 326 L 8.58x58 κ receptor 4DJH AT1 receptor 6DO1
H8 327 C 8.59x59 κ receptor 4DJH β2-adrenoceptor 3SN6
H8 328 L 8.60x60 - - - -
C-term 329 R - - - - -
C-term 330 C - - - - -
C-term 331 C - - - - -
C-term 332 L - - - - -