PAF receptor homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Inactive
VERSION
2021-01-08
MODEL
TEMPLATES
5UIW (CCR5)
4MBS (CCR5)
6RNK (succinate receptor)
5ZKQ (PAF receptor)
6RZ5 (CysLT1 receptor)
6PWC (NTS1 receptor)
4XNW (P2Y1 receptor)
6JOD (AT2 receptor)
5LWE (CCR9)
None
4MBS (CCR5)
6RNK (succinate receptor)
5ZKQ (PAF receptor)
6RZ5 (CysLT1 receptor)
6PWC (NTS1 receptor)
4XNW (P2Y1 receptor)
6JOD (AT2 receptor)
5LWE (CCR9)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 77.7 | 15.3 | 7.0 |
| Side-chains | 23.2 | 60.5 | 16.2 |
Number of backbone templates: 9
Number of rotamer templates: 49
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 5 | D | CCR5 | 5UIW | CCR5 | 5UIW | |
| N-term | 6 | S | CCR5 | 5UIW | CCR5 | 5UIW | |
| N-term | 7 | S | CCR5 | 5UIW | CCR5 | 5UIW | |
| N-term | 8 | H | CCR5 | 5UIW | CCR5 | 5UIW | |
| N-term | 9 | M | CCR5 | 5UIW | CCR5 | 5UIW | |
| TM1 | 10 | D | 1.27x27 | CCR5 | 5UIW | - | - |
| TM1 | 11 | S | 1.28x28 | CCR5 | 5UIW | δ receptor | 4N6H |
| TM1 | 12 | E | 1.29x29 | CCR5 | 5UIW | ETB receptor | 5X93 |
| TM1 | 13 | F | 1.30x30 | CCR5 | 5UIW | CCR7 | 6QZH |
| TM1 | 14 | R | 1.31x31 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM1 | 15 | Y | 1.32x32 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM1 | 16 | T | 1.33x33 | CCR5 | 5UIW | CB2 receptor | 5ZTY |
| TM1 | 17 | L | 1.34x34 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM1 | 18 | F | 1.35x35 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM1 | 19 | P | 1.36x36 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM1 | 20 | I | 1.37x37 | CCR5 | 5UIW | CCR7 | 6QZH |
| TM1 | 21 | V | 1.38x38 | CCR5 | 5UIW | κ receptor | 6VI4 |
| TM1 | 22 | Y | 1.39x39 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM1 | 23 | S | 1.40x40 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM1 | 24 | I | 1.41x41 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM1 | 25 | I | 1.42x42 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM1 | 26 | F | 1.43x43 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM1 | 27 | V | 1.44x44 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM1 | 28 | L | 1.45x45 | CCR5 | 5UIW | apelin receptor | 5VBL |
| TM1 | 29 | G | 1.46x46 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM1 | 30 | V | 1.47x47 | CCR5 | 5UIW | H1 receptor | 3RZE |
| TM1 | 31 | I | 1.48x48 | CCR5 | 5UIW | OX2 receptor | 5WS3 |
| TM1 | 32 | A | 1.49x49 | CCR5 | 5UIW | LPA1 receptor | 4Z35 |
| TM1 | 33 | N | 1.50x50 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM1 | 34 | G | 1.51x51 | CCR5 | 5UIW | CCR7 | 6QZH |
| TM1 | 35 | Y | 1.52x52 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM1 | 36 | V | 1.53x53 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM1 | 37 | L | 1.54x54 | CCR5 | 5UIW | apelin receptor | 5VBL |
| TM1 | 38 | W | 1.55x55 | CCR5 | 5UIW | apelin receptor | 5VBL |
| TM1 | 39 | V | 1.56x56 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM1 | 40 | F | 1.57x57 | CCR5 | 5UIW | M5 receptor | 6OL9 |
| TM1 | 41 | A | 1.58x58 | CCR5 | 5UIW | NTS1 receptor | 4BUO |
| TM1 | 42 | R | 1.59x59 | CCR5 | 5UIW | apelin receptor | 5VBL |
| TM1 | 43 | L | 1.60x60 | CCR5 | 5UIW | - | - |
| TM1 | 44 | Y | 1.61x61 | succinate receptor | 6RNK | - | - |
| ICL1 | 45 | P | - | - | - | - | |
| ICL1 | 46 | C | CCR5 | 4MBS | - | - | |
| ICL1 | 47 | K | CCR5 | 4MBS | - | - | |
| ICL1 | 48 | K | - | - | - | - | |
| TM2 | 49 | F | 2.36x36 | PAF receptor | 5ZKQ | - | - |
| TM2 | 50 | N | 2.37x37 | CCR5 | 5UIW | MT1 receptor | 6ME2 |
| TM2 | 51 | E | 2.38x38 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM2 | 52 | I | 2.39x39 | CCR5 | 5UIW | LPA1 receptor | 4Z35 |
| TM2 | 53 | K | 2.40x40 | CCR5 | 5UIW | GnRH1 receptor | 7BR3 |
| TM2 | 54 | I | 2.41x41 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM2 | 55 | F | 2.42x42 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM2 | 56 | M | 2.43x43 | CCR5 | 5UIW | OT receptor | 6TPK |
| TM2 | 57 | V | 2.44x44 | CCR5 | 5UIW | OX2 receptor | 5WS3 |
| TM2 | 58 | N | 2.45x45 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM2 | 59 | L | 2.46x46 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM2 | 60 | T | 2.47x47 | CCR5 | 5UIW | GnRH1 receptor | 7BR3 |
| TM2 | 61 | M | 2.48x48 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM2 | 62 | A | 2.49x49 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM2 | 63 | D | 2.50x50 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM2 | 64 | M | 2.51x51 | CCR5 | 5UIW | 5-HT2C receptor | 6BQH |
| TM2 | 65 | L | 2.52x52 | CCR5 | 5UIW | CCR2 | 5T1A |
| TM2 | 66 | F | 2.53x53 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM2 | 67 | L | 2.54x54 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM2 | 68 | I | 2.55x55 | CCR5 | 5UIW | CCR2 | 5T1A |
| TM2 | 69 | T | 2.56x56 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM2 | 70 | L | 2.57x57 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM2 | 71 | P | 2.58x58 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM2 | 72 | L | 2.59x59 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM2 | 73 | W | 2.60x60 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM2 | 74 | I | 2.61x61 | CCR5 | 5UIW | H1 receptor | 3RZE |
| TM2 | 75 | V | 2.62x62 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM2 | 76 | Y | 2.63x63 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM2 | 77 | Y | 2.64x64 | CCR5 | 5UIW | κ receptor | 6VI4 |
| TM2 | 78 | Q | 2.65x65 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM2 | 79 | N | 2.66x66 | CCR5 | 5UIW | CCR2 | 5T1A |
| TM2 | 80 | Q | 2.67x67 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| ECL1 | 81 | G | - | - | - | - | |
| ECL1 | 82 | N | 23.49x49 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| ECL1 | 83 | W | 23.50x50 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| ECL1 | 84 | I | 23.51x51 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| ECL1 | 85 | L | 23.52x52 | - | - | - | - |
| TM3 | 86 | P | 3.21x21 | CCR5 | 5UIW | 5-HT2C receptor | 6BQH |
| TM3 | 87 | K | 3.22x22 | CCR5 | 5UIW | α2A-adrenoceptor | 6KUX |
| TM3 | 88 | F | 3.23x23 | CCR5 | 5UIW | apelin receptor | 5VBL |
| TM3 | 89 | L | 3.24x24 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM3 | 90 | C | 3.25x25 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM3 | 91 | N | 3.26x26 | CCR5 | 5UIW | Rhodopsin | 1GZM |
| TM3 | 92 | V | 3.27x27 | CCR5 | 5UIW | CXCR2 | 6LFL |
| TM3 | 93 | A | 3.28x28 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM3 | 94 | G | 3.29x29 | CCR5 | 5UIW | Rhodopsin | 1GZM |
| TM3 | 95 | C | 3.30x30 | CCR5 | 5UIW | A2A receptor | 5IU4 |
| TM3 | 96 | L | 3.31x31 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM3 | 97 | F | 3.32x32 | CCR5 | 5UIW | DP2 receptor | 6D27 |
| TM3 | 98 | F | 3.33x33 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM3 | 99 | I | 3.34x34 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM3 | 100 | N | 3.35x35 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM3 | 101 | T | 3.36x36 | CCR5 | 5UIW | NTS1 receptor | 4BUO |
| TM3 | 102 | Y | 3.37x37 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM3 | 103 | C | 3.38x38 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM3 | 104 | S | 3.39x39 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM3 | 105 | V | 3.40x40 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM3 | 106 | A | 3.41x41 | CCR5 | 5UIW | LPA1 receptor | 4Z35 |
| TM3 | 107 | F | 3.42x42 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM3 | 108 | L | 3.43x43 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM3 | 109 | G | 3.44x44 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM3 | 110 | V | 3.45x45 | CCR5 | 5UIW | M5 receptor | 6OL9 |
| TM3 | 111 | I | 3.46x46 | CCR5 | 5UIW | CCR7 | 6QZH |
| TM3 | 112 | T | 3.47x47 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM3 | 113 | Y | 3.48x48 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM3 | 114 | N | 3.49x49 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM3 | 115 | R | 3.50x50 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM3 | 116 | F | 3.51x51 | CCR5 | 5UIW | C5a1 receptor | 5O9H |
| TM3 | 117 | Q | 3.52x52 | CCR5 | 5UIW | Y1 receptor | 5ZBH |
| TM3 | 118 | A | 3.53x53 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM3 | 119 | V | 3.54x54 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM3 | 120 | T | 3.55x55 | CCR5 | 5UIW | M5 receptor | 6OL9 |
| TM3 | 121 | R | 3.56x56 | CCR5 | 5UIW | apelin receptor | 5VBL |
| ICL2 | 122 | P | 34.50x50 | - | - | - | - |
| ICL2 | 123 | I | 34.51x51 | CysLT1 receptor | 6RZ5 | - | - |
| ICL2 | 124 | K | 34.52x52 | CysLT1 receptor | 6RZ5 | δ receptor | 4N6H |
| ICL2 | 125 | T | 34.53x53 | CysLT1 receptor | 6RZ5 | CXCR2 | 6LFO |
| ICL2 | 126 | A | 34.54x54 | CysLT1 receptor | 6RZ5 | EP3 receptor | 6M9T |
| ICL2 | 127 | Q | 34.55x55 | CysLT1 receptor | 6RZ5 | GPR52 | 6LI3 |
| ICL2 | 128 | A | 34.56x56 | CysLT1 receptor | 6RZ5 | CCR5 | 5UIW |
| ICL2 | 129 | N | 34.57x57 | - | - | - | - |
| TM4 | 130 | T | 4.38x38 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM4 | 131 | R | 4.39x39 | CCR5 | 5UIW | apelin receptor | 5VBL |
| TM4 | 132 | K | 4.40x40 | CCR5 | 5UIW | OX2 receptor | 5WS3 |
| TM4 | 133 | R | 4.41x41 | CCR5 | 5UIW | NTS1 receptor | 4BUO |
| TM4 | 134 | G | 4.42x42 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM4 | 135 | I | 4.43x43 | CCR5 | 5UIW | 5-HT2C receptor | 6BQH |
| TM4 | 136 | S | 4.44x44 | CCR5 | 5UIW | GnRH1 receptor | 7BR3 |
| TM4 | 137 | L | 4.45x45 | CCR5 | 5UIW | BLT1 receptor | 5X33 |
| TM4 | 138 | S | 4.46x46 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM4 | 139 | L | 4.47x47 | CCR5 | 5UIW | CXCR2 | 6LFL |
| TM4 | 140 | V | 4.48x48 | CCR5 | 5UIW | apelin receptor | 5VBL |
| TM4 | 141 | I | 4.49x49 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM4 | 142 | W | 4.50x50 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM4 | 143 | V | 4.51x51 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM4 | 144 | A | 4.52x52 | CCR5 | 5UIW | BLT1 receptor | 5X33 |
| TM4 | 145 | I | 4.53x53 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM4 | 146 | V | 4.54x54 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM4 | 147 | G | 4.55x55 | CCR5 | 5UIW | δ receptor | 4N6H |
| TM4 | 148 | A | 4.56x56 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM4 | 149 | A | 4.57x57 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM4 | 150 | S | 4.58x58 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM4 | 151 | Y | 4.59x59 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM4 | 152 | F | 4.60x60 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM4 | 153 | L | 4.61x61 | CCR5 | 5UIW | Rhodopsin | 1GZM |
| TM4 | 154 | I | 4.62x62 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM4 | 155 | L | 4.63x63 | CCR5 | 5UIW | CCR7 | 6QZH |
| ECL2 | 156 | D | - | - | - | - | |
| ECL2 | 157 | S | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 158 | T | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 159 | N | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 160 | T | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 161 | V | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 162 | P | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 163 | D | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 164 | S | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 165 | A | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 166 | G | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 167 | S | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 168 | G | NTS1 receptor | 6PWC | NTS1 receptor | 6PWC | |
| ECL2 | 169 | N | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 170 | V | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 171 | T | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 172 | R | - | - | - | - | |
| ECL2 | 173 | C | 45.50x50 | CCR5 | 5UIW | CCR5 | 5UIW |
| ECL2 | 174 | F | 45.51x51 | CCR5 | 5UIW | M3 receptor | 5ZHP |
| ECL2 | 175 | E | 45.52x52 | CCR5 | 5UIW | CXCR2 | 6LFL |
| ECL2 | 176 | H | CCR5 | 5UIW | CCR5 | 5UIW | |
| ECL2 | 177 | Y | CCR5 | 5UIW | - | - | |
| ECL2 | 178 | E | CCR5 | 5UIW | - | - | |
| ECL2 | 179 | K | CCR5 | 5UIW | - | - | |
| ECL2 | 180 | G | CCR5 | 5UIW | - | - | |
| TM5 | 181 | S | 5.33x33 | CCR5 | 5UIW | κ receptor | 4DJH |
| TM5 | 182 | V | 5.34x34 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM5 | 183 | P | 5.35x35 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM5 | 184 | V | 5.36x36 | CCR5 | 5UIW | CXCR4 | 3ODU |
| TM5 | 185 | L | 5.37x37 | CCR5 | 5UIW | κ receptor | 6VI4 |
| TM5 | 186 | I | 5.38x38 | CCR5 | 5UIW | OX1 receptor | 6TO7 |
| TM5 | 187 | I | 5.39x39 | CCR5 | 5UIW | CCR7 | 6QZH |
| TM5 | 188 | H | 5.40x40 | CCR5 | 5UIW | OX2 receptor | 5WS3 |
| TM5 | 189 | I | 5.41x41 | CCR5 | 5UIW | CCR2 | 5T1A |
| TM5 | 190 | F | 5.42x42 | CCR5 | 5UIW | BLT1 receptor | 5X33 |
| TM5 | 191 | I | 5.43x43 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM5 | 192 | V | 5.44x44 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM5 | 193 | F | 5.45x45 | CCR5 | 5UIW | BLT1 receptor | 5X33 |
| TM5 | 194 | S | 5.46x46 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM5 | 195 | F | 5.47x47 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM5 | 196 | F | 5.48x48 | CCR5 | 5UIW | ghrelin receptor | 6KO5 |
| TM5 | 197 | L | 5.49x49 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM5 | 198 | V | 5.50x50 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM5 | 199 | F | 5.51x51 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM5 | 200 | L | 5.52x52 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM5 | 201 | I | 5.53x53 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM5 | 202 | I | 5.54x54 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM5 | 203 | L | 5.55x55 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM5 | 204 | F | 5.56x56 | CCR5 | 5UIW | CCR7 | 6QZH |
| TM5 | 205 | C | 5.57x57 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM5 | 206 | N | 5.58x58 | CCR5 | 5UIW | NTS1 receptor | 4BUO |
| TM5 | 207 | L | 5.59x59 | CCR5 | 5UIW | CCR7 | 6QZH |
| TM5 | 208 | V | 5.60x60 | CCR5 | 5UIW | CCR7 | 6QZH |
| TM5 | 209 | I | 5.61x61 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM5 | 210 | I | 5.62x62 | CCR5 | 5UIW | CCR7 | 6QZH |
| TM5 | 211 | R | 5.63x63 | CCR5 | 5UIW | CXCR2 | 6LFL |
| TM5 | 212 | T | 5.64x64 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM5 | 213 | L | 5.65x65 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM5 | 214 | L | 5.66x66 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM5 | 215 | M | 5.67x67 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM5 | 216 | Q | 5.68x68 | P2Y1 receptor | 4XNW | β2-adrenoceptor | 6OBA |
| ICL3 | 217 | P | - | - | - | - | |
| ICL3 | 218 | V | - | - | - | - | |
| ICL3 | 219 | Q | - | - | - | - | |
| ICL3 | 220 | Q | - | - | - | - | |
| TM6 | 221 | Q | 6.24x25 | AT2 receptor | 6JOD | 5-HT2A receptor | 6A94 |
| TM6 | 222 | R | 6.25x26 | AT2 receptor | 6JOD | NTS1 receptor | 4BUO |
| TM6 | 223 | N | 6.26x27 | AT2 receptor | 6JOD | PAR1 | 3VW7 |
| TM6 | 224 | A | 6.27x28 | CCR5 | 5UIW | 5-HT1B receptor | 4IAQ |
| TM6 | 225 | E | 6.28x29 | CCR5 | 5UIW | Y1 receptor | 5ZBH |
| TM6 | 226 | V | 6.29x30 | CCR5 | 5UIW | - | - |
| TM6 | 227 | K | 6.30x31 | CCR5 | 5UIW | ghrelin receptor | 6KO5 |
| TM6 | 228 | R | 6.31x32 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM6 | 229 | R | 6.32x33 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM6 | 230 | A | 6.33x34 | CCR5 | 5UIW | OX2 receptor | 5WS3 |
| TM6 | 231 | L | 6.34x35 | CCR5 | 5UIW | NTS1 receptor | 4BUO |
| TM6 | 232 | W | 6.35x36 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM6 | 233 | M | 6.36x37 | CCR5 | 5UIW | MT1 receptor | 6ME2 |
| TM6 | 234 | V | 6.37x38 | CCR5 | 5UIW | apelin receptor | 5VBL |
| TM6 | 235 | C | 6.38x39 | CCR5 | 5UIW | ETB receptor | 5X93 |
| TM6 | 236 | T | 6.39x40 | CCR5 | 5UIW | Rhodopsin | 6I9K |
| TM6 | 237 | V | 6.40x41 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM6 | 238 | L | 6.41x42 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM6 | 239 | A | 6.42x43 | CCR5 | 5UIW | CXCR4 | 3ODU |
| TM6 | 240 | V | 6.43x44 | CCR5 | 5UIW | EP4 receptor | 5YWY |
| TM6 | 241 | F | 6.44x45 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM6 | 242 | I | 6.45x46 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM6 | 243 | I | 6.46x461 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM6 | 244 | C | 6.47x47 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM6 | 245 | F | 6.48x48 | CCR5 | 5UIW | MT1 receptor | 6ME2 |
| TM6 | 246 | V | 6.49x49 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM6 | 247 | P | 6.50x50 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM6 | 248 | H | 6.51x51 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM6 | 249 | H | 6.52x52 | CCR5 | 5UIW | apelin receptor | 5VBL |
| TM6 | 250 | V | 6.53x53 | CCR5 | 5UIW | BLT1 receptor | 5X33 |
| TM6 | 251 | V | 6.54x54 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM6 | 252 | Q | 6.55x55 | CCR5 | 5UIW | OT receptor | 6TPK |
| TM6 | 253 | L | 6.56x56 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM6 | 254 | P | 6.57x57 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM6 | 255 | W | 6.58x58 | CCR5 | 5UIW | δ receptor | 4N6H |
| TM6 | 256 | T | 6.59x59 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM6 | 257 | L | 6.60x60 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM6 | 258 | A | 6.61x61 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM6 | 259 | E | 6.62x62 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM6 | 260 | L | 6.63x63 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM6 | 261 | G | 6.64x64 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| ECL3 | 262 | F | - | - | - | - | |
| ECL3 | 263 | Q | - | - | - | - | |
| TM7 | 264 | D | 7.24x23 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM7 | 265 | S | 7.25x24 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM7 | 266 | K | 7.26x25 | CCR5 | 5UIW | - | - |
| TM7 | 267 | F | 7.27x26 | CCR5 | 5UIW | apelin receptor | 5VBL |
| TM7 | 268 | H | 7.28x27 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM7 | 269 | Q | 7.29x28 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM7 | 270 | A | 7.30x29 | CCR5 | 5UIW | CCR9 | 5LWE |
| TM7 | 271 | I | 7.31x30 | CCR5 | 5UIW | CXCR2 | 6LFL |
| TM7 | 272 | N | 7.32x31 | CCR5 | 5UIW | CCR7 | 6QZH |
| TM7 | 273 | D | 7.33x32 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM7 | 274 | A | 7.34x33 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM7 | 275 | H | 7.35x34 | CCR5 | 5UIW | H1 receptor | 3RZE |
| TM7 | 276 | Q | 7.36x35 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM7 | 277 | V | 7.37x36 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM7 | 278 | T | 7.38x37 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM7 | 279 | L | 7.39x38 | CCR5 | 5UIW | S1P1 receptor | 3V2Y |
| TM7 | 280 | C | 7.40x39 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM7 | 281 | L | 7.41x40 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM7 | 282 | L | 7.42x41 | CCR5 | 5UIW | PAF receptor | 5ZKQ |
| TM7 | 283 | S | 7.43x42 | CCR5 | 5UIW | ETB receptor | 5X93 |
| TM7 | 284 | T | 7.44x43 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM7 | 285 | N | 7.45x45 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM7 | 286 | C | 7.46x46 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM7 | 287 | V | 7.47x47 | CCR5 | 5UIW | DP2 receptor | 6D27 |
| TM7 | 288 | L | 7.48x48 | CCR5 | 5UIW | AT1 receptor | 4ZUD |
| TM7 | 289 | D | 7.49x49 | CCR5 | 5UIW | GnRH1 receptor | 7BR3 |
| TM7 | 290 | P | 7.50x50 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM7 | 291 | V | 7.51x51 | CCR5 | 5UIW | CCR9 | 5LWE |
| TM7 | 292 | I | 7.52x52 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM7 | 293 | Y | 7.53x53 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM7 | 294 | C | 7.54x54 | CCR5 | 5UIW | NK1 receptor | 6HLP |
| TM7 | 295 | F | 7.55x55 | CCR5 | 5UIW | CCR5 | 5UIW |
| TM7 | 296 | L | 7.56x56 | CCR5 | 5UIW | κ receptor | 6VI4 |
| TM7 | 297 | T | 7.57x57 | - | - | - | - |
| TM7 | 298 | K | 7.58x58 | - | - | - | - |
| TM7 | 299 | K | 7.59x59 | - | - | - | - |
| H8 | 300 | F | 8.50x50 | CCR5 | 5UIW | CCR5 | 5UIW |
| H8 | 301 | R | 8.51x51 | CCR5 | 5UIW | CCR5 | 5UIW |
| H8 | 302 | K | 8.52x52 | CCR5 | 5UIW | H1 receptor | 3RZE |
| H8 | 303 | H | 8.53x53 | CCR5 | 5UIW | PAR2 | 5NDD |
| H8 | 304 | L | 8.54x54 | CCR5 | 5UIW | CCR5 | 5UIW |
| H8 | 305 | T | 8.55x55 | CCR5 | 5UIW | apelin receptor | 5VBL |
| H8 | 306 | E | 8.56x56 | CCR5 | 5UIW | β2-adrenoceptor | 2RH1 |
| H8 | 307 | K | 8.57x57 | CCR5 | 5UIW | EP4 receptor | 5YWY |
| H8 | 308 | F | 8.58x58 | CCR5 | 5UIW | CCR5 | 5UIW |
| H8 | 309 | Y | 8.59x59 | CCR5 | 5UIW | - | - |
| H8 | 310 | S | 8.60x60 | CCR9 | 5LWE | MT1 receptor | 6ME2 |
| H8 | 311 | M | 8.61x61 | CCR9 | 5LWE | GPR52 | 6LI1 |
| H8 | 312 | R | 8.62x62 | CCR9 | 5LWE | US28 | 4XT1 |
| H8 | 313 | S | 8.63x63 | CCR9 | 5LWE | - | - |
| C-term | 314 | S | - | - | - | - | |
| C-term | 315 | R | - | - | - | - | |
| C-term | 316 | K | - | - | - | - | |
| C-term | 317 | C | - | - | - | - | |
| C-term | 318 | S | - | - | - | - |