PAF receptor homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Active
VERSION
2021-02-08
MODEL
TEMPLATES
6WWZ (CCR6)
6RNK (succinate receptor)
5ZKQ (PAF receptor)
6RZ5 (CysLT1 receptor)
6PWC (NTS1 receptor)
5UIW (CCR5)
6JOD (AT2 receptor)
5LWE (CCR9)
None
6RNK (succinate receptor)
5ZKQ (PAF receptor)
6RZ5 (CysLT1 receptor)
6PWC (NTS1 receptor)
5UIW (CCR5)
6JOD (AT2 receptor)
5LWE (CCR9)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 77.4 | 15.6 | 7.0 |
| Side-chains | 22.6 | 62.1 | 15.3 |
Number of backbone templates: 8
Number of rotamer templates: 39
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 5 | D | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| N-term | 6 | S | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| N-term | 7 | S | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| N-term | 8 | H | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| N-term | 9 | M | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| TM1 | 10 | D | 1.27x27 | CCR6 | 6WWZ | - | - |
| TM1 | 11 | S | 1.28x28 | CCR6 | 6WWZ | δ receptor | 6PT2 |
| TM1 | 12 | E | 1.29x29 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM1 | 13 | F | 1.30x30 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 14 | R | 1.31x31 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM1 | 15 | Y | 1.32x32 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM1 | 16 | T | 1.33x33 | CCR6 | 6WWZ | CB2 receptor | 6PT0 |
| TM1 | 17 | L | 1.34x34 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM1 | 18 | F | 1.35x35 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM1 | 19 | P | 1.36x36 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 20 | I | 1.37x37 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 21 | V | 1.38x38 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM1 | 22 | Y | 1.39x39 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 23 | S | 1.40x40 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 24 | I | 1.41x41 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM1 | 25 | I | 1.42x42 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 26 | F | 1.43x43 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM1 | 27 | V | 1.44x44 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 28 | L | 1.45x45 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM1 | 29 | G | 1.46x46 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 30 | V | 1.47x47 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM1 | 31 | I | 1.48x48 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM1 | 32 | A | 1.49x49 | CCR6 | 6WWZ | GPBA receptor | 7CFN |
| TM1 | 33 | N | 1.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 34 | G | 1.51x51 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM1 | 35 | Y | 1.52x52 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM1 | 36 | V | 1.53x53 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 37 | L | 1.54x54 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM1 | 38 | W | 1.55x55 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM1 | 39 | V | 1.56x56 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM1 | 40 | F | 1.57x57 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 41 | A | 1.58x58 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM1 | 42 | R | 1.59x59 | CCR6 | 6WWZ | δ receptor | 6PT2 |
| TM1 | 43 | L | 1.60x60 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM1 | 44 | Y | 1.61x61 | succinate receptor | 6RNK | - | - |
| ICL1 | 45 | P | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| ICL1 | 46 | C | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| ICL1 | 47 | K | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| ICL1 | 48 | K | CCR6 | 6WWZ | CCR6 | 6WWZ | |
| TM2 | 49 | F | 2.36x36 | PAF receptor | 5ZKQ | - | - |
| TM2 | 50 | N | 2.37x37 | CCR6 | 6WWZ | 5-HT2C receptor | 6BQG |
| TM2 | 51 | E | 2.38x38 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM2 | 52 | I | 2.39x39 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM2 | 53 | K | 2.40x40 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM2 | 54 | I | 2.41x41 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM2 | 55 | F | 2.42x42 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM2 | 56 | M | 2.43x43 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM2 | 57 | V | 2.44x44 | CCR6 | 6WWZ | D2 receptor | 6VMS |
| TM2 | 58 | N | 2.45x45 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 59 | L | 2.46x46 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM2 | 60 | T | 2.47x47 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM2 | 61 | M | 2.48x48 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM2 | 62 | A | 2.49x49 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 63 | D | 2.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 64 | M | 2.51x51 | CCR6 | 6WWZ | 5-HT2C receptor | 6BQG |
| TM2 | 65 | L | 2.52x52 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 66 | F | 2.53x53 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 67 | L | 2.54x54 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM2 | 68 | I | 2.55x55 | CCR6 | 6WWZ | 5-HT1B receptor | 6G79 |
| TM2 | 69 | T | 2.56x56 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 70 | L | 2.57x57 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 71 | P | 2.58x58 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 72 | L | 2.59x59 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM2 | 73 | W | 2.60x60 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 74 | I | 2.61x61 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM2 | 75 | V | 2.62x62 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM2 | 76 | Y | 2.63x63 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM2 | 77 | Y | 2.64x64 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM2 | 78 | Q | 2.65x65 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM2 | 79 | N | 2.66x66 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM2 | 80 | Q | 2.67x67 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| ECL1 | 81 | G | - | - | - | - | |
| ECL1 | 82 | N | 23.49x49 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| ECL1 | 83 | W | 23.50x50 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| ECL1 | 84 | I | 23.51x51 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| ECL1 | 85 | L | 23.52x52 | - | - | - | - |
| TM3 | 86 | P | 3.21x21 | CCR6 | 6WWZ | 5-HT2C receptor | 6BQG |
| TM3 | 87 | K | 3.22x22 | CCR6 | 6WWZ | CB2 receptor | 6PT0 |
| TM3 | 88 | F | 3.23x23 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM3 | 89 | L | 3.24x24 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM3 | 90 | C | 3.25x25 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 91 | N | 3.26x26 | CCR6 | 6WWZ | Rhodopsin | 4ZWJ |
| TM3 | 92 | V | 3.27x27 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM3 | 93 | A | 3.28x28 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM3 | 94 | G | 3.29x29 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM3 | 95 | C | 3.30x30 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| TM3 | 96 | L | 3.31x31 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM3 | 97 | F | 3.32x32 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM3 | 98 | F | 3.33x33 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM3 | 99 | I | 3.34x34 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 100 | N | 3.35x35 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 101 | T | 3.36x36 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM3 | 102 | Y | 3.37x37 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM3 | 103 | C | 3.38x38 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 104 | S | 3.39x39 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM3 | 105 | V | 3.40x40 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM3 | 106 | A | 3.41x41 | CCR6 | 6WWZ | GPBA receptor | 7CFN |
| TM3 | 107 | F | 3.42x42 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM3 | 108 | L | 3.43x43 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 109 | G | 3.44x44 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM3 | 110 | V | 3.45x45 | CCR6 | 6WWZ | 5-HT1B receptor | 6G79 |
| TM3 | 111 | I | 3.46x46 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 112 | T | 3.47x47 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM3 | 113 | Y | 3.48x48 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM3 | 114 | N | 3.49x49 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM3 | 115 | R | 3.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 116 | F | 3.51x51 | CCR6 | 6WWZ | LPA6 receptor | 5XSZ |
| TM3 | 117 | Q | 3.52x52 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM3 | 118 | A | 3.53x53 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM3 | 119 | V | 3.54x54 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM3 | 120 | T | 3.55x55 | CCR6 | 6WWZ | M1 receptor | 6OIJ |
| TM3 | 121 | R | 3.56x56 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| ICL2 | 122 | P | 34.50x50 | - | - | - | - |
| ICL2 | 123 | I | 34.51x51 | CysLT1 receptor | 6RZ5 | - | - |
| ICL2 | 124 | K | 34.52x52 | CysLT1 receptor | 6RZ5 | CCR6 | 6WWZ |
| ICL2 | 125 | T | 34.53x53 | CysLT1 receptor | 6RZ5 | CXCR2 | 6LFO |
| ICL2 | 126 | A | 34.54x54 | CysLT1 receptor | 6RZ5 | EP3 receptor | 6M9T |
| ICL2 | 127 | Q | 34.55x55 | CysLT1 receptor | 6RZ5 | GPR52 | 6LI3 |
| ICL2 | 128 | A | 34.56x56 | CysLT1 receptor | 6RZ5 | CCR5 | 5UIW |
| ICL2 | 129 | N | 34.57x57 | - | - | - | - |
| TM4 | 130 | T | 4.38x38 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM4 | 131 | R | 4.39x39 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM4 | 132 | K | 4.40x40 | CCR6 | 6WWZ | US28 | 4XT1 |
| TM4 | 133 | R | 4.41x41 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 134 | G | 4.42x42 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM4 | 135 | I | 4.43x43 | CCR6 | 6WWZ | 5-HT2C receptor | 6BQG |
| TM4 | 136 | S | 4.44x44 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM4 | 137 | L | 4.45x45 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM4 | 138 | S | 4.46x46 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM4 | 139 | L | 4.47x47 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 140 | V | 4.48x48 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 141 | I | 4.49x49 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM4 | 142 | W | 4.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 143 | V | 4.51x51 | CCR6 | 6WWZ | δ receptor | 6PT2 |
| TM4 | 144 | A | 4.52x52 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM4 | 145 | I | 4.53x53 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM4 | 146 | V | 4.54x54 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM4 | 147 | G | 4.55x55 | CCR6 | 6WWZ | δ receptor | 6PT2 |
| TM4 | 148 | A | 4.56x56 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM4 | 149 | A | 4.57x57 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM4 | 150 | S | 4.58x58 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM4 | 151 | Y | 4.59x59 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM4 | 152 | F | 4.60x60 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM4 | 153 | L | 4.61x61 | CCR6 | 6WWZ | Rhodopsin | 4ZWJ |
| TM4 | 154 | I | 4.62x62 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM4 | 155 | L | 4.63x63 | CCR6 | 6WWZ | κ receptor | 6B73 |
| ECL2 | 156 | D | - | - | - | - | |
| ECL2 | 157 | S | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 158 | T | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 159 | N | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 160 | T | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 161 | V | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 162 | P | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 163 | D | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 164 | S | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 165 | A | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 166 | G | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 167 | S | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 168 | G | NTS1 receptor | 6PWC | NTS1 receptor | 6PWC | |
| ECL2 | 169 | N | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 170 | V | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 171 | T | NTS1 receptor | 6PWC | - | - | |
| ECL2 | 172 | R | - | - | - | - | |
| ECL2 | 173 | C | 45.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| ECL2 | 174 | F | 45.51x51 | CCR6 | 6WWZ | EP3 receptor | 6M9T |
| ECL2 | 175 | E | 45.52x52 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| ECL2 | 176 | H | - | - | - | - | |
| ECL2 | 177 | Y | CCR5 | 5UIW | - | - | |
| ECL2 | 178 | E | CCR5 | 5UIW | - | - | |
| ECL2 | 179 | K | CCR5 | 5UIW | - | - | |
| ECL2 | 180 | G | - | - | - | - | |
| TM5 | 181 | S | 5.33x33 | CCR6 | 6WWZ | κ receptor | 4DJH |
| TM5 | 182 | V | 5.34x34 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM5 | 183 | P | 5.35x35 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM5 | 184 | V | 5.36x36 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM5 | 185 | L | 5.37x37 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 186 | I | 5.38x38 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM5 | 187 | I | 5.39x39 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM5 | 188 | H | 5.40x40 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM5 | 189 | I | 5.41x41 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM5 | 190 | F | 5.42x42 | CCR6 | 6WWZ | 5-HT2B receptor | 5TUD |
| TM5 | 191 | I | 5.43x43 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM5 | 192 | V | 5.44x44 | CCR6 | 6WWZ | GPBA receptor | 7CFN |
| TM5 | 193 | F | 5.45x45 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM5 | 194 | S | 5.46x46 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM5 | 195 | F | 5.47x47 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM5 | 196 | F | 5.48x48 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 197 | L | 5.49x49 | CCR6 | 6WWZ | FPR2/ALX | 6LW5 |
| TM5 | 198 | V | 5.50x50 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM5 | 199 | F | 5.51x51 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM5 | 200 | L | 5.52x52 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM5 | 201 | I | 5.53x53 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM5 | 202 | I | 5.54x54 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM5 | 203 | L | 5.55x55 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM5 | 204 | F | 5.56x56 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 205 | C | 5.57x57 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 206 | N | 5.58x58 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM5 | 207 | L | 5.59x59 | CCR6 | 6WWZ | EP3 receptor | 6M9T |
| TM5 | 208 | V | 5.60x60 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM5 | 209 | I | 5.61x61 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 210 | I | 5.62x62 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM5 | 211 | R | 5.63x63 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM5 | 212 | T | 5.64x64 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 213 | L | 5.65x65 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM5 | 214 | L | 5.66x66 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM5 | 215 | M | 5.67x67 | CCR6 | 6WWZ | - | - |
| TM5 | 216 | Q | 5.68x68 | CCR6 | 6WWZ | β2-adrenoceptor | 6OBA |
| ICL3 | 217 | P | - | - | - | - | |
| ICL3 | 218 | V | - | - | - | - | |
| ICL3 | 219 | Q | - | - | - | - | |
| ICL3 | 220 | Q | - | - | - | - | |
| TM6 | 221 | Q | 6.24x25 | AT2 receptor | 6JOD | 5-HT2C receptor | 6BQG |
| TM6 | 222 | R | 6.25x26 | AT2 receptor | 6JOD | NTS1 receptor | 5T04 |
| TM6 | 223 | N | 6.26x27 | AT2 receptor | 6JOD | PAR1 | 3VW7 |
| TM6 | 224 | A | 6.27x28 | AT2 receptor | 6JOD | 5-HT1B receptor | 6G79 |
| TM6 | 225 | E | 6.28x29 | AT2 receptor | 6JOD | Y1 receptor | 5ZBH |
| TM6 | 226 | V | 6.29x30 | CCR6 | 6WWZ | - | - |
| TM6 | 227 | K | 6.30x31 | CCR6 | 6WWZ | Rhodopsin | 4ZWJ |
| TM6 | 228 | R | 6.31x32 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM6 | 229 | R | 6.32x33 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM6 | 230 | A | 6.33x34 | CCR6 | 6WWZ | M1 receptor | 6OIJ |
| TM6 | 231 | L | 6.34x35 | CCR6 | 6WWZ | NTS1 receptor | 4XES |
| TM6 | 232 | W | 6.35x36 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM6 | 233 | M | 6.36x37 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM6 | 234 | V | 6.37x38 | CCR6 | 6WWZ | CB1 receptor | 6N4B |
| TM6 | 235 | C | 6.38x39 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM6 | 236 | T | 6.39x40 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM6 | 237 | V | 6.40x41 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 238 | L | 6.41x42 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 239 | A | 6.42x43 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM6 | 240 | V | 6.43x44 | CCR6 | 6WWZ | EP4 receptor | 7D7M |
| TM6 | 241 | F | 6.44x45 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM6 | 242 | I | 6.45x46 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM6 | 243 | I | 6.46x461 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM6 | 244 | C | 6.47x47 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM6 | 245 | F | 6.48x48 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM6 | 246 | V | 6.49x49 | CCR6 | 6WWZ | Rhodopsin | 4ZWJ |
| TM6 | 247 | P | 6.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 248 | H | 6.51x51 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 249 | H | 6.52x52 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM6 | 250 | V | 6.53x53 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM6 | 251 | V | 6.54x54 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 252 | Q | 6.55x55 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM6 | 253 | L | 6.56x56 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM6 | 254 | P | 6.57x57 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM6 | 255 | W | 6.58x58 | CCR6 | 6WWZ | δ receptor | 6PT2 |
| TM6 | 256 | T | 6.59x59 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM6 | 257 | L | 6.60x60 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM6 | 258 | A | 6.61x61 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM6 | 259 | E | 6.62x62 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM6 | 260 | L | 6.63x63 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| TM6 | 261 | G | 6.64x64 | PAF receptor | 5ZKQ | PAF receptor | 5ZKQ |
| ECL3 | 262 | F | - | - | - | - | |
| ECL3 | 263 | Q | - | - | - | - | |
| TM7 | 264 | D | 7.24x23 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM7 | 265 | S | 7.25x24 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM7 | 266 | K | 7.26x25 | CCR6 | 6WWZ | - | - |
| TM7 | 267 | F | 7.27x26 | CCR6 | 6WWZ | US28 | 5WB1 |
| TM7 | 268 | H | 7.28x27 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM7 | 269 | Q | 7.29x28 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM7 | 270 | A | 7.30x29 | CCR6 | 6WWZ | κ receptor | 6B73 |
| TM7 | 271 | I | 7.31x30 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 272 | N | 7.32x31 | CCR6 | 6WWZ | M2 receptor | 4MQT |
| TM7 | 273 | D | 7.33x32 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM7 | 274 | A | 7.34x33 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM7 | 275 | H | 7.35x34 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM7 | 276 | Q | 7.36x35 | CCR6 | 6WWZ | α2B-adrenoceptor | 6K41 |
| TM7 | 277 | V | 7.37x36 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 278 | T | 7.38x37 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 279 | L | 7.39x38 | CCR6 | 6WWZ | GPBA receptor | 7CFN |
| TM7 | 280 | C | 7.40x39 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM7 | 281 | L | 7.41x40 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 282 | L | 7.42x41 | CCR6 | 6WWZ | PAF receptor | 5ZKQ |
| TM7 | 283 | S | 7.43x42 | CCR6 | 6WWZ | EP3 receptor | 6M9T |
| TM7 | 284 | T | 7.44x43 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM7 | 285 | N | 7.45x45 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM7 | 286 | C | 7.46x46 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 287 | V | 7.47x47 | CCR6 | 6WWZ | Rhodopsin | 5DYS |
| TM7 | 288 | L | 7.48x48 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 289 | D | 7.49x49 | CCR6 | 6WWZ | EP3 receptor | 6M9T |
| TM7 | 290 | P | 7.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 291 | V | 7.51x51 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 292 | I | 7.52x52 | CCR6 | 6WWZ | CXCR2 | 6LFO |
| TM7 | 293 | Y | 7.53x53 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 294 | C | 7.54x54 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| TM7 | 295 | F | 7.55x55 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| TM7 | 296 | L | 7.56x56 | CCR6 | 6WWZ | AT1 receptor | 6OS2 |
| TM7 | 297 | T | 7.57x57 | - | - | - | - |
| TM7 | 298 | K | 7.58x58 | - | - | - | - |
| TM7 | 299 | K | 7.59x59 | - | - | - | - |
| H8 | 300 | F | 8.50x50 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| H8 | 301 | R | 8.51x51 | CCR6 | 6WWZ | CCR6 | 6WWZ |
| H8 | 302 | K | 8.52x52 | CCR6 | 6WWZ | D2 receptor | 6VMS |
| H8 | 303 | H | 8.53x53 | CCR6 | 6WWZ | PAR2 | 5NDD |
| H8 | 304 | L | 8.54x54 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| H8 | 305 | T | 8.55x55 | CCR6 | 6WWZ | apelin receptor | 5VBL |
| H8 | 306 | E | 8.56x56 | CCR6 | 6WWZ | β2-adrenoceptor | 3SN6 |
| H8 | 307 | K | 8.57x57 | CCR6 | 6WWZ | succinate receptor | 6RNK |
| H8 | 308 | F | 8.58x58 | CCR6 | 6WWZ | AT2 receptor | 6JOD |
| H8 | 309 | Y | 8.59x59 | CCR6 | 6WWZ | - | - |
| H8 | 310 | S | 8.60x60 | CCR6 | 6WWZ | A2A receptor | 4UHR |
| H8 | 311 | M | 8.61x61 | CCR6 | 6WWZ | GPR52 | 6LI3 |
| H8 | 312 | R | 8.62x62 | CCR6 | 6WWZ | US28 | 4XT1 |
| H8 | 313 | S | 8.63x63 | CCR9 | 5LWE | - | - |
| C-term | 314 | S | - | - | - | - | |
| C-term | 315 | R | - | - | - | - | |
| C-term | 316 | K | - | - | - | - | |
| C-term | 317 | C | - | - | - | - | |
| C-term | 318 | S | - | - | - | - |