MRGPRG homology model
PROTEIN CLASS
Class A (Rhodopsin)
RECEPTOR
SPECIES
Homo sapiens
STATE
Active
VERSION
2022-06-19
MODEL
TEMPLATES
7S8L (MRGPRX2)
7VDL (MRGPRX2)
7S8P (MRGPRX4)
7M8W (DP2 receptor)
None
7VDL (MRGPRX2)
7S8P (MRGPRX4)
7M8W (DP2 receptor)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 80.9 | 7.1 | 12.0 |
| Side-chains | 27.3 | 46.1 | 26.6 |
Number of backbone templates: 4
Number of rotamer templates: 42
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 7 | L | - | - | - | - | - |
| N-term | 8 | W | - | - | - | - | - |
| N-term | 9 | R | - | - | - | - | - |
| N-term | 10 | T | - | - | - | - | - |
| N-term | 11 | F | - | - | - | - | - |
| TM1 | 12 | D | 1.32x32 | MRGPRX2 | 7S8L | DP2 receptor | 7M8W |
| TM1 | 13 | S | 1.33x33 | MRGPRX2 | 7VDL | MT1 receptor | 6ME2 |
| TM1 | 14 | V | 1.34x34 | MRGPRX2 | 7VDL | OX1 receptor | 6TO7 |
| TM1 | 15 | V | 1.35x35 | MRGPRX2 | 7VDL | CXCR2 | 6LFL |
| TM1 | 16 | F | 1.36x36 | MRGPRX2 | 7VDL | FFA1 receptor | 5TZY |
| TM1 | 17 | Y | 1.37x37 | MRGPRX2 | 7VDL | - | - |
| TM1 | 18 | L | 1.38x38 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 19 | T | 1.39x39 | MRGPRX2 | 7VDL | M5 receptor | 6OL9 |
| TM1 | 20 | L | 1.40x40 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 21 | I | 1.41x41 | MRGPRX2 | 7VDL | AT1 receptor | 4ZUD |
| TM1 | 22 | V | 1.42x42 | MRGPRX2 | 7VDL | CXCR2 | 6LFL |
| TM1 | 23 | G | 1.43x43 | MRGPRX2 | 7VDL | MC4 receptor | 6W25 |
| TM1 | 24 | L | 1.44x44 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 25 | G | 1.45x45 | MRGPRX2 | 7VDL | NOP receptor | 5DHG |
| TM1 | 26 | G | 1.46x46 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 27 | P | 1.47x47 | MRGPRX2 | 7VDL | - | - |
| TM1 | 28 | V | 1.48x48 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 29 | G | 1.49x49 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 30 | N | 1.50x50 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 31 | G | 1.51x51 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 32 | L | 1.52x52 | MRGPRX2 | 7VDL | AT1 receptor | 4ZUD |
| TM1 | 33 | V | 1.53x53 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 34 | L | 1.54x54 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 35 | W | 1.55x55 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 36 | N | 1.56x56 | MRGPRX2 | 7VDL | - | - |
| TM1 | 37 | L | 1.57x57 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 38 | G | 1.58x58 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 39 | F | 1.59x59 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 40 | R | 1.60x60 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM1 | 41 | I | 1.61x61 | MRGPRX2 | 7VDL | - | - |
| ICL1 | 42 | K | - | MRGPRX2 | 7VDL | - | - |
| ICL1 | 43 | K | - | MRGPRX2 | 7VDL | - | - |
| TM2 | 44 | G | 2.37x37 | MRGPRX2 | 7VDL | - | - |
| TM2 | 45 | P | 2.38x38 | MRGPRX2 | 7VDL | PAR2 | 5NDD |
| TM2 | 46 | F | 2.39x39 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM2 | 47 | S | 2.40x40 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM2 | 48 | I | 2.41x41 | MRGPRX2 | 7VDL | apelin receptor | 5VBL |
| TM2 | 49 | Y | 2.42x42 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM2 | 50 | L | 2.43x43 | MRGPRX2 | 7VDL | AT1 receptor | 4ZUD |
| TM2 | 51 | L | 2.44x44 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM2 | 52 | H | 2.45x45 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM2 | 53 | L | 2.46x46 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM2 | 54 | A | 2.47x47 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM2 | 55 | A | 2.48x48 | MRGPRX2 | 7VDL | A2A receptor | 5IU4 |
| TM2 | 56 | A | 2.49x49 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM2 | 57 | D | 2.50x50 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM2 | 58 | F | 2.51x51 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM2 | 59 | L | 2.52x52 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM2 | 60 | F | 2.53x53 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM2 | 61 | L | 2.54x54 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM2 | 62 | S | 2.55x55 | MRGPRX2 | 7VDL | CysLT2 receptor | 6RZ6 |
| TM2 | 63 | C | 2.56x56 | MRGPRX2 | 7VDL | OX1 receptor | 6TO7 |
| TM2 | 64 | R | 2.57x57 | MRGPRX2 | 7VDL | - | - |
| TM2 | 65 | V | 2.58x58 | MRGPRX2 | 7VDL | CB1 receptor | 5TGZ |
| TM2 | 66 | G | 2.59x59 | MRGPRX2 | 7VDL | - | - |
| TM2 | 67 | F | 2.60x60 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM2 | 68 | S | 2.61x61 | MRGPRX2 | 7VDL | μ receptor | 4DKL |
| TM2 | 69 | V | 2.62x62 | MRGPRX2 | 7VDL | AT1 receptor | 4ZUD |
| TM2 | 70 | A | 2.63x63 | MRGPRX2 | 7VDL | CCR9 | 5LWE |
| ECL1 | 71 | Q | - | - | - | - | - |
| ECL1 | 72 | A | - | - | - | - | - |
| ECL1 | 73 | A | - | - | - | - | - |
| ECL1 | 74 | L | - | - | - | - | - |
| ECL1 | 75 | G | - | - | - | - | - |
| ECL1 | 76 | A | - | - | - | - | - |
| TM3 | 77 | Q | 3.24x24 | MRGPRX4 | 7S8P | S1P1 receptor | 3V2Y |
| TM3 | 78 | D | 3.25x25 | MRGPRX2 | 7VDL | - | - |
| TM3 | 79 | T | 3.26x26 | MRGPRX2 | 7VDL | - | - |
| TM3 | 80 | L | 3.27x27 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM3 | 81 | Y | 3.28x28 | MRGPRX2 | 7VDL | Rhodopsin | 6I9K |
| TM3 | 82 | F | 3.29x29 | MRGPRX2 | 7VDL | CCR7 | 6QZH |
| TM3 | 83 | V | 3.30x30 | MRGPRX2 | 7VDL | CXCR4 | 3ODU |
| TM3 | 84 | L | 3.31x31 | MRGPRX2 | 7VDL | CXCR2 | 6LFL |
| TM3 | 85 | T | 3.32x32 | MRGPRX2 | 7VDL | - | - |
| TM3 | 86 | F | 3.33x33 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM3 | 87 | L | 3.34x34 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM3 | 88 | W | 3.35x35 | MRGPRX2 | 7VDL | - | - |
| TM3 | 89 | F | 3.36x36 | MRGPRX2 | 7VDL | CXCR2 | 6LFL |
| TM3 | 90 | A | 3.37x37 | MRGPRX2 | 7VDL | - | - |
| TM3 | 91 | V | 3.38x38 | MRGPRX2 | 7VDL | OX1 receptor | 6TO7 |
| TM3 | 92 | G | 3.39x39 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM3 | 93 | L | 3.40x40 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM3 | 94 | W | 3.41x41 | MRGPRX2 | 7VDL | CXCR2 | 6LFL |
| TM3 | 95 | L | 3.42x42 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM3 | 96 | L | 3.43x43 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM3 | 97 | A | 3.44x44 | MRGPRX2 | 7VDL | CXCR2 | 6LFL |
| TM3 | 98 | A | 3.45x45 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM3 | 99 | F | 3.46x46 | MRGPRX2 | 7VDL | - | - |
| TM3 | 100 | S | 3.47x47 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM3 | 101 | V | 3.48x48 | MRGPRX2 | 7VDL | CXCR2 | 6LFL |
| TM3 | 102 | E | 3.49x49 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM3 | 103 | R | 3.50x50 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM3 | 104 | C | 3.51x51 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM3 | 105 | L | 3.52x52 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM3 | 106 | S | 3.53x53 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM3 | 107 | D | 3.54x54 | MRGPRX2 | 7VDL | - | - |
| TM3 | 108 | L | 3.55x55 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM3 | 109 | F | 3.56x56 | MRGPRX2 | 7VDL | CysLT1 receptor | 6RZ4 |
| ICL2 | 110 | P | 34.50x50 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| ICL2 | 111 | A | 34.51x51 | MRGPRX2 | 7VDL | C5a1 receptor | 5O9H |
| ICL2 | 112 | C | 34.52x52 | MRGPRX2 | 7VDL | - | - |
| ICL2 | 113 | Y | 34.53x53 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| ICL2 | 114 | Q | 34.54x54 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| ICL2 | 115 | G | 34.55x55 | MRGPRX2 | 7VDL | P2Y1 receptor | 4XNW |
| ICL2 | 116 | C | 34.56x56 | MRGPRX2 | 7VDL | - | - |
| ICL2 | 117 | R | 34.57x57 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM4 | 118 | P | 4.38x38 | DP2 receptor | 7M8W | - | - |
| TM4 | 119 | R | 4.39x39 | DP2 receptor | 7M8W | CXCR2 | 6LFL |
| TM4 | 120 | H | 4.40x40 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM4 | 121 | A | 4.41x41 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM4 | 122 | S | 4.42x42 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM4 | 123 | A | 4.43x43 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM4 | 124 | V | 4.44x44 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM4 | 125 | L | 4.45x45 | MRGPRX2 | 7VDL | CysLT2 receptor | 6RZ6 |
| TM4 | 126 | C | 4.46x46 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM4 | 127 | A | 4.47x47 | MRGPRX2 | 7VDL | apelin receptor | 5VBL |
| TM4 | 128 | L | 4.48x48 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM4 | 129 | V | 4.49x49 | MRGPRX2 | 7VDL | P2Y1 receptor | 4XNW |
| TM4 | 130 | W | 4.50x50 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM4 | 131 | T | 4.51x51 | MRGPRX2 | 7VDL | CB1 receptor | 5TGZ |
| TM4 | 132 | P | 4.52x52 | MRGPRX2 | 7VDL | CXCR4 | 3ODU |
| TM4 | 133 | T | 4.53x53 | MRGPRX2 | 7VDL | MT2 receptor | 6ME7 |
| TM4 | 134 | L | 4.54x54 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM4 | 135 | P | 4.55x55 | MRGPRX2 | 7VDL | - | - |
| TM4 | 136 | A | 4.56x56 | MRGPRX2 | 7VDL | AT1 receptor | 4ZUD |
| TM4 | 137 | V | 4.57x57 | MRGPRX2 | 7VDL | PAR1 | 3VW7 |
| TM4 | 138 | P | 4.58x58 | MRGPRX2 | 7VDL | - | - |
| TM4 | 139 | L | 4.59x59 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM4 | 140 | P | 4.60x60 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM4 | 141 | A | 4.61x61 | MRGPRX2 | 7VDL | AT1 receptor | 4ZUD |
| TM4 | 142 | N | 4.62x62 | MRGPRX2 | 7VDL | - | - |
| TM4 | 143 | A | 4.63x63 | MRGPRX2 | 7VDL | OX1 receptor | 6TO7 |
| TM4 | 144 | C | 4.64x64 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| ECL2 | 145 | G | - | - | - | - | - |
| ECL2 | 146 | L | - | - | - | - | - |
| ECL2 | 147 | L | - | - | - | - | - |
| ECL2 | 148 | R | - | - | - | - | - |
| ECL2 | 149 | N | - | - | - | - | - |
| ECL2 | 150 | S | - | - | - | - | - |
| ECL2 | 151 | A | - | - | - | - | - |
| ECL2 | 152 | C | - | - | - | - | - |
| ECL2 | 153 | P | - | - | - | - | - |
| TM5 | 154 | L | 5.32x32 | MRGPRX2 | 7VDL | - | - |
| TM5 | 155 | V | 5.33x33 | MRGPRX2 | 7VDL | PAR2 | 5NDD |
| TM5 | 156 | C | 5.34x34 | MRGPRX2 | 7VDL | - | - |
| TM5 | 157 | P | 5.35x35 | MRGPRX2 | 7VDL | PAF receptor | 5ZKQ |
| TM5 | 158 | R | 5.36x36 | MRGPRX2 | 7VDL | Y1 receptor | 5ZBH |
| TM5 | 159 | Y | 5.37x37 | MRGPRX2 | 7VDL | PAR1 | 3VW7 |
| TM5 | 160 | H | 5.38x38 | MRGPRX2 | 7VDL | S1P1 receptor | 3V2Y |
| TM5 | 161 | V | 5.39x39 | MRGPRX2 | 7VDL | C5a1 receptor | 6C1Q |
| TM5 | 162 | A | 5.40x40 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM5 | 163 | S | 5.41x41 | MRGPRX2 | 7VDL | OX1 receptor | 6TO7 |
| TM5 | 164 | V | 5.42x42 | MRGPRX2 | 7VDL | C5a1 receptor | 6C1Q |
| TM5 | 165 | T | 5.43x43 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM5 | 166 | W | 5.44x44 | MRGPRX2 | 7VDL | - | - |
| TM5 | 167 | F | 5.45x45 | MRGPRX2 | 7VDL | CysLT1 receptor | 6RZ4 |
| TM5 | 168 | L | 5.46x46 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM5 | 169 | V | 5.47x47 | MRGPRX2 | 7VDL | CB1 receptor | 5TGZ |
| TM5 | 170 | L | 5.48x48 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM5 | 171 | A | 5.49x49 | MRGPRX2 | 7VDL | OX1 receptor | 6TO7 |
| TM5 | 172 | R | 5.50x50 | MRGPRX2 | 7VDL | - | - |
| TM5 | 173 | V | 5.51x51 | MRGPRX2 | 7VDL | μ receptor | 4DKL |
| TM5 | 174 | A | 5.52x52 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM5 | 175 | W | 5.53x53 | MRGPRX2 | 7VDL | - | - |
| TM5 | 176 | T | 5.54x54 | MRGPRX2 | 7VDL | PAR2 | 5NDD |
| TM5 | 177 | A | 5.55x55 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM5 | 178 | G | 5.56x56 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM5 | 179 | V | 5.57x57 | MRGPRX2 | 7VDL | α2A-adrenoceptor | 6KUX |
| TM5 | 180 | V | 5.58x58 | MRGPRX2 | 7VDL | - | - |
| TM5 | 181 | L | 5.59x59 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM5 | 182 | F | 5.60x60 | MRGPRX2 | 7VDL | CXCR2 | 6LFL |
| TM5 | 183 | V | 5.61x61 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM5 | 184 | W | 5.62x62 | MRGPRX2 | 7VDL | AT1 receptor | 4YAY |
| TM5 | 185 | V | 5.63x63 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM5 | 186 | T | 5.64x64 | MRGPRX2 | 7VDL | CXCR2 | 6LFL |
| TM5 | 187 | C | 5.65x65 | MRGPRX2 | 7VDL | - | - |
| TM5 | 188 | C | 5.66x66 | MRGPRX2 | 7VDL | GPR52 | 6LI1 |
| TM5 | 189 | S | 5.67x67 | MRGPRX2 | 7VDL | C5a1 receptor | 6C1Q |
| ICL3 | 190 | T | - | - | - | - | - |
| ICL3 | 191 | R | - | - | - | - | - |
| ICL3 | 192 | P | - | - | - | - | - |
| TM6 | 193 | R | 6.30x30 | MRGPRX2 | 7VDL | OX1 receptor | 6TO7 |
| TM6 | 194 | P | 6.31x31 | MRGPRX2 | 7VDL | - | - |
| TM6 | 195 | R | 6.32x32 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM6 | 196 | L | 6.33x33 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM6 | 197 | Y | 6.34x34 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM6 | 198 | G | 6.35x35 | MRGPRX2 | 7VDL | - | - |
| TM6 | 199 | I | 6.36x36 | MRGPRX2 | 7VDL | AT1 receptor | 4ZUD |
| TM6 | 200 | V | 6.37x37 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM6 | 201 | L | 6.38x38 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM6 | 202 | G | 6.39x39 | MRGPRX2 | 7VDL | FFA1 receptor | 5TZY |
| TM6 | 203 | A | 6.40x40 | MRGPRX2 | 7VDL | PAR1 | 3VW7 |
| TM6 | 204 | L | 6.41x41 | MRGPRX2 | 7VDL | OX1 receptor | 4ZJ8 |
| TM6 | 205 | L | 6.42x42 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM6 | 206 | L | 6.43x43 | MRGPRX2 | 7VDL | CCK1 receptor | 7F8Y |
| TM6 | 207 | L | 6.44x44 | MRGPRX2 | 7VDL | CB2 receptor | 5ZTY |
| TM6 | 208 | F | 6.45x45 | MRGPRX2 | 7VDL | AT1 receptor | 4ZUD |
| TM6 | 209 | F | 6.46x46 | MRGPRX2 | 7VDL | AT1 receptor | 4ZUD |
| TM6 | 210 | C | 6.47x47 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM6 | 211 | G | 6.48x48 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM6 | 212 | L | 6.49x49 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM6 | 213 | P | 6.50x50 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM6 | 214 | S | 6.51x51 | MRGPRX2 | 7VDL | PAR2 | 5NDD |
| TM6 | 215 | V | 6.52x52 | MRGPRX2 | 7VDL | EP4 receptor | 5YWY |
| TM6 | 216 | F | 6.53x53 | MRGPRX2 | 7VDL | α2A-adrenoceptor | 6KUX |
| TM6 | 217 | Y | 6.54x54 | MRGPRX2 | 7VDL | μ receptor | 4DKL |
| TM6 | 218 | W | 6.55x55 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM6 | 219 | S | 6.56x56 | MRGPRX2 | 7VDL | CXCR4 | 3ODU |
| TM6 | 220 | L | 6.57x57 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM6 | 221 | Q | 6.58x58 | MRGPRX2 | 7VDL | CCR7 | 6QZH |
| TM6 | 222 | P | 6.59x59 | MRGPRX2 | 7VDL | 5-HT1B receptor | 4IAQ |
| TM6 | 223 | L | 6.60x60 | MRGPRX2 | 7VDL | AT1 receptor | 4ZUD |
| TM6 | 224 | L | 6.61x61 | MRGPRX2 | 7VDL | PAR2 | 5NDD |
| ECL3 | 225 | N | - | - | - | - | - |
| ECL3 | 226 | F | - | - | - | - | - |
| ECL3 | 227 | L | - | - | - | - | - |
| ECL3 | 228 | L | - | - | - | - | - |
| TM7 | 229 | P | 7.32x31 | MRGPRX2 | 7VDL | GPR52 | 6LI1 |
| TM7 | 230 | V | 7.33x32 | MRGPRX2 | 7VDL | μ receptor | 4DKL |
| TM7 | 231 | F | 7.34x33 | MRGPRX2 | 7VDL | NTS1 receptor | 4BUO |
| TM7 | 232 | S | 7.35x34 | MRGPRX2 | 7VDL | GPR52 | 6LI1 |
| TM7 | 233 | P | 7.36x35 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM7 | 234 | L | 7.37x36 | MRGPRX2 | 7VDL | C5a1 receptor | 6C1Q |
| TM7 | 235 | A | 7.38x37 | MRGPRX2 | 7VDL | PAR2 | 5NDD |
| TM7 | 236 | T | 7.39x38 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM7 | 237 | L | 7.40x39 | MRGPRX2 | 7VDL | CCK1 receptor | 7F8Y |
| TM7 | 238 | L | 7.41x40 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM7 | 239 | A | 7.42x41 | MRGPRX2 | 7VDL | DP2 receptor | 7M8W |
| TM7 | 240 | C | 7.43x42 | MRGPRX2 | 7VDL | CCR7 | 6QZH |
| TM7 | 241 | V | 7.44x43 | MRGPRX2 | 7VDL | apelin receptor | 5VBL |
| TM7 | 242 | N | 7.45x45 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM7 | 243 | S | 7.46x46 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM7 | 244 | S | 7.47x47 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM7 | 245 | S | 7.48x48 | MRGPRX2 | 7VDL | - | - |
| TM7 | 246 | K | 7.49x49 | MRGPRX2 | 7VDL | OT receptor | 6TPK |
| TM7 | 247 | P | 7.50x50 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM7 | 248 | L | 7.51x51 | MRGPRX2 | 7VDL | AT1 receptor | 4ZUD |
| TM7 | 249 | I | 7.52x52 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM7 | 250 | Y | 7.53x53 | MRGPRX2 | 7VDL | MRGPRX2 | 7VDL |
| TM7 | 251 | S | 7.54x54 | MRGPRX2 | 7VDL | LPA1 receptor | 4Z35 |
| TM7 | 252 | G | 7.55x55 | MRGPRX2 | 7VDL | - | - |
| TM7 | 253 | L | 7.56x56 | MRGPRX2 | 7VDL | OX1 receptor | 6TO7 |
| H8 | 254 | G | 8.47x47 | DP2 receptor | 7M8W | CXCR2 | 6LFL |
| H8 | 255 | R | 8.48x48 | DP2 receptor | 7M8W | A2A receptor | 5IU4 |
| H8 | 256 | Q | 8.49x49 | DP2 receptor | 7M8W | Rhodopsin | 1U19 |
| H8 | 257 | P | 8.50x50 | DP2 receptor | 7M8W | - | - |
| H8 | 258 | G | 8.51x51 | DP2 receptor | 7M8W | - | - |
| H8 | 259 | K | 8.52x52 | DP2 receptor | 7M8W | MC4 receptor | 6W25 |
| H8 | 260 | R | 8.53x53 | DP2 receptor | 7M8W | CysLT2 receptor | 6RZ6 |
| H8 | 261 | E | 8.54x54 | DP2 receptor | 7M8W | - | - |
| H8 | 262 | P | 8.55x55 | DP2 receptor | 7M8W | - | - |
| H8 | 263 | L | 8.56x56 | DP2 receptor | 7M8W | M1 receptor | 6ZFZ |
| H8 | 264 | R | 8.57x57 | DP2 receptor | 7M8W | - | - |
| H8 | 265 | S | 8.58x58 | DP2 receptor | 7M8W | GPR52 | 6LI1 |
| H8 | 266 | V | 8.59x59 | DP2 receptor | 7M8W | MT1 receptor | 6ME2 |
| H8 | 267 | L | 8.60x60 | DP2 receptor | 7M8W | - | - |
| H8 | 268 | R | 8.61x61 | DP2 receptor | 7M8W | M1 receptor | 6ZFZ |
| C-term | 269 | R | - | - | - | - | - |
| C-term | 270 | A | - | - | - | - | - |
| C-term | 271 | L | - | - | - | - | - |
| C-term | 272 | G | - | - | - | - | - |
| C-term | 273 | E | - | - | - | - | - |