ADGRB2 homology model

PROTEIN CLASS

Class B2 (Adhesion)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active

VERSION

2022-06-19

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

NGL is a WebGL based 3D viewer powered by MMTF.

MAIN TEMPLATE

ADGRL3 (sequence similarity: 19%) PDB: 7SF7

TEMPLATES

7WU2 (ADGRD1)
7SF7 (ADGRL3)
7WU3 (ADGRF1)
6PB0 (CRF1 receptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 78.9 7.9 13.3
Side-chains 25.8 22.9 51.3

Number of backbone templates: 4
Number of rotamer templates: 11

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 920 P - ADGRD1 7WU2 ADGRD1 7WU2
N-term 921 P - ADGRD1 7WU2 ADGRD1 7WU2
N-term 922 K - ADGRD1 7WU2 ADGRD1 7WU2
N-term 923 D - ADGRD1 7WU2 ADGRD1 7WU2
N-term 924 L - ADGRD1 7WU2 ADGRD1 7WU2
TM1 925 T 1.32x32 ADGRD1 7WU2 - -
TM1 926 L 1.33x33 ADGRD1 7WU2 - -
TM1 927 E 1.34x34 ADGRD1 7WU2 PTH1 receptor 6FJ3
TM1 928 L 1.35x35 ADGRL3 7SF7 - -
TM1 929 A 1.36x36 ADGRL3 7SF7 calcitonin receptor-like receptor 7KNU
TM1 930 G 1.37x37 ADGRL3 7SF7 - -
TM1 931 S 1.38x38 ADGRL3 7SF7 glucagon receptor 5YQZ
TM1 932 P 1.39x39 ADGRL3 7SF7 - -
TM1 933 S 1.40x40 ADGRL3 7SF7 - -
TM1 934 V 1.41x41 ADGRL3 7SF7 ADGRL3 7SF7
TM1 935 P 1.42x42 ADGRL3 7SF7 - -
TM1 936 L 1.43x43 ADGRL3 7SF7 - -
TM1 937 V 1.44x44 ADGRL3 7SF7 - -
TM1 938 I 1.45x45 ADGRL3 7SF7 calcitonin receptor-like receptor 7KNU
TM1 939 G 1.46x46 ADGRL3 7SF7 ADGRL3 7SF7
TM1 940 C 1.47x47 ADGRL3 7SF7 - -
TM1 941 A 1.48x48 ADGRL3 7SF7 GLP-1 receptor 6LN2
TM1 942 V 1.49x49 ADGRL3 7SF7 PTH1 receptor 6FJ3
TM1 943 S 1.50x50 ADGRL3 7SF7 ADGRL3 7SF7
TM1 944 C 1.51x51 ADGRL3 7SF7 - -
TM1 945 M 1.52x52 ADGRL3 7SF7 - -
TM1 946 A 1.53x53 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM1 947 L 1.54x54 ADGRL3 7SF7 ADGRL3 7SF7
TM1 948 L 1.55x55 ADGRL3 7SF7 ADGRL3 7SF7
TM1 949 T 1.56x56 ADGRL3 7SF7 - -
TM1 950 L 1.57x57 ADGRL3 7SF7 - -
TM1 951 L 1.58x58 ADGRL3 7SF7 calcitonin receptor-like receptor 7KNU
TM1 952 A 1.59x59 ADGRL3 7SF7 glucagon receptor 5YQZ
TM1 953 I 1.60x60 ADGRL3 7SF7 calcitonin receptor-like receptor 7KNU
TM1 954 Y 1.61x61 ADGRL3 7SF7 - -
TM1 955 A 1.62x62 ADGRL3 7SF7 PTH1 receptor 6FJ3
TM1 956 A 1.63x63 ADGRL3 7SF7 - -
TM1 957 F 1.64x64 ADGRD1 7WU2 calcitonin receptor-like receptor 7KNU
ICL1 958 W - - - - -
ICL1 959 R 12.48x48 ADGRF1 7WU3 CRF1 receptor 4Z9G
ICL1 960 F 12.49x49 ADGRF1 7WU3 - -
ICL1 961 I 12.50x50 ADGRF1 7WU3 ADGRF1 7WU3
ICL1 962 K 12.51x51 - - - -
TM2 963 S 2.44x44 ADGRF1 7WU3 - -
TM2 964 E 2.45x45 ADGRF1 7WU3 - -
TM2 965 R 2.46x46 ADGRL3 7SF7 ADGRL3 7SF7
TM2 966 S 2.47x47 ADGRL3 7SF7 - -
TM2 967 I 2.48x48 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM2 968 I 2.49x49 ADGRL3 7SF7 ADGRL3 7SF7
TM2 969 L 2.50x50 ADGRL3 7SF7 - -
TM2 970 L 2.51x51 ADGRL3 7SF7 GLP-1 receptor 6LN2
TM2 971 N 2.52x52 ADGRL3 7SF7 ADGRL3 7SF7
TM2 972 F 2.53x53 ADGRL3 7SF7 - -
TM2 973 C 2.54x54 ADGRL3 7SF7 ADGRL3 7SF7
TM2 974 L 2.55x55 ADGRL3 7SF7 glucagon receptor 5EE7
TM2 975 S 2.56x56 ADGRL3 7SF7 ADGRL3 7SF7
TM2 976 I 2.57x57 ADGRL3 7SF7 - -
TM2 977 L 2.58x58 ADGRL3 7SF7 - -
TM2 978 A 2.59x59 ADGRL3 7SF7 - -
TM2 979 S 2.60x60 ADGRL3 7SF7 - -
TM2 980 N 2.61x61 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM2 981 I 2.62x62 ADGRL3 7SF7 - -
TM2 982 L 2.63x63 ADGRL3 7SF7 ADGRL3 7SF7
TM2 983 I 2.64x64 ADGRL3 7SF7 PTH1 receptor 6FJ3
TM2 984 L 2.65x65 ADGRL3 7SF7 ADGRL3 7SF7
TM2 985 V 2.66x66 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM2 986 G 2.67x67 ADGRL3 7SF7 ADGRL3 7SF7
ECL1 987 Q - - - - -
ECL1 988 S - - - - -
ECL1 989 R - - - - -
ECL1 990 V - - - - -
ECL1 991 L - - - - -
ECL1 992 S - - - - -
ECL1 993 K - - - - -
TM3 994 G 3.27x27 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM3 995 V 3.28x28 ADGRL3 7SF7 - -
TM3 996 C 3.29x29 ADGRL3 7SF7 ADGRL3 7SF7
TM3 997 T 3.30x30 ADGRL3 7SF7 - -
TM3 998 M 3.31x31 ADGRL3 7SF7 - -
TM3 999 T 3.32x32 ADGRL3 7SF7 - -
TM3 1000 A 3.33x33 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1001 A 3.34x34 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1002 F 3.35x35 ADGRL3 7SF7 glucagon receptor 5YQZ
TM3 1003 L 3.36x36 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1004 H 3.37x37 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1005 F 3.38x38 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1006 F 3.39x39 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1007 F 3.40x40 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1008 L 3.41x41 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1009 S 3.42x42 ADGRL3 7SF7 - -
TM3 1010 S 3.43x43 ADGRL3 7SF7 - -
TM3 1011 F 3.44x44 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1012 C 3.45x45 ADGRL3 7SF7 glucagon receptor 5YQZ
TM3 1013 W 3.46x46 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1014 V 3.47x47 ADGRL3 7SF7 - -
TM3 1015 L 3.48x48 ADGRL3 7SF7 calcitonin receptor-like receptor 7KNU
TM3 1016 T 3.49x49 ADGRL3 7SF7 - -
TM3 1017 E 3.50x50 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1018 A 3.51x51 ADGRL3 7SF7 - -
TM3 1019 W 3.52x52 ADGRL3 7SF7 - -
TM3 1020 Q 3.53x53 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1021 S 3.54x54 ADGRL3 7SF7 - -
TM3 1022 Y 3.55x55 ADGRL3 7SF7 ADGRL3 7SF7
TM3 1023 L 3.56x56 ADGRL3 7SF7 - -
TM3 1024 A 3.57x57 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM3 1025 V 3.58x58 ADGRL3 7SF7 - -
TM3 1026 I 3.59x59 ADGRL3 7SF7 - -
TM3 1027 G 3.60x60 ADGRD1 7WU2 - -
ICL2 1028 R - - - - -
ICL2 1029 M - - - - -
ICL2 1030 R - - - - -
ICL2 1031 T - - - - -
ICL2 1032 R - - - - -
ICL2 1033 L - - - - -
TM4 1034 V 4.41x42 ADGRL3 7SF7 - -
TM4 1035 R 4.42x43 ADGRL3 7SF7 ADGRL3 7SF7
TM4 1036 K 4.43x44 ADGRL3 7SF7 ADGRL3 7SF7
TM4 1037 R 4.44x45 ADGRL3 7SF7 - -
TM4 1038 F 4.45x46 ADGRL3 7SF7 ADGRL3 7SF7
TM4 1039 L 4.46x47 ADGRL3 7SF7 glucagon receptor 5YQZ
TM4 1040 C 4.47x48 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM4 1041 L 4.48x49 ADGRL3 7SF7 calcitonin receptor-like receptor 7KNU
TM4 1042 G 4.49x491 ADGRL3 7SF7 ADGRL3 7SF7
TM4 1043 W 4.50x50 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM4 1044 G 4.51x51 ADGRL3 7SF7 ADGRL3 7SF7
TM4 1045 L 4.52x52 ADGRL3 7SF7 PTH1 receptor 6FJ3
TM4 1046 P 4.53x53 ADGRL3 7SF7 ADGRL3 7SF7
TM4 1047 A 4.54x54 ADGRL3 7SF7 ADGRL3 7SF7
TM4 1048 L 4.55x55 ADGRL3 7SF7 ADGRL3 7SF7
TM4 1049 V 4.56x56 ADGRL3 7SF7 - -
TM4 1050 V 4.57x57 ADGRL3 7SF7 ADGRL3 7SF7
TM4 1051 A 4.58x58 ADGRL3 7SF7 ADGRL3 7SF7
TM4 1052 V 4.59x59 ADGRL3 7SF7 ADGRL3 7SF7
TM4 1053 S 4.60x60 ADGRL3 7SF7 ADGRL3 7SF7
TM4 1054 V 4.61x61 ADGRL3 7SF7 PTH1 receptor 6FJ3
TM4 1055 G 4.62x62 ADGRL3 7SF7 - -
TM4 1056 F 4.63x63 ADGRL3 7SF7 - -
TM4 1057 T 4.64x64 ADGRL3 7SF7 - -
ECL2 1058 R - ADGRL3 7SF7 - -
ECL2 1059 T - ADGRL3 7SF7 - -
ECL2 1060 K - ADGRL3 7SF7 - -
ECL2 1061 G - ADGRL3 7SF7 - -
ECL2 1062 Y - ADGRL3 7SF7 - -
ECL2 1063 G - ADGRL3 7SF7 - -
ECL2 1064 T - ADGRL3 7SF7 - -
ECL2 1065 S - ADGRL3 7SF7 - -
ECL2 1066 S - ADGRL3 7SF7 - -
ECL2 1067 Y - - - - -
ECL2 1068 C 45.50x50 ADGRL3 7SF7 ADGRL3 7SF7
ECL2 1069 W 45.51x51 ADGRL3 7SF7 ADGRL3 7SF7
ECL2 1070 L 45.52x52 ADGRL3 7SF7 - -
ECL2 1071 S - ADGRL3 7SF7 ADGRL3 7SF7
ECL2 1072 L - ADGRL3 7SF7 - -
ECL2 1073 E - ADGRL3 7SF7 - -
ECL2 1074 G - ADGRL3 7SF7 ADGRL3 7SF7
TM5 1075 G 5.34x34 ADGRD1 7WU2 ADGRD1 7WU2
TM5 1076 L 5.35x35 ADGRD1 7WU2 - -
TM5 1077 L 5.36x36 ADGRL3 7SF7 calcitonin receptor-like receptor 7KNU
TM5 1078 Y 5.37x37 ADGRL3 7SF7 - -
TM5 1079 A 5.38x38 ADGRL3 7SF7 - -
TM5 1080 F 5.39x39 ADGRL3 7SF7 ADGRL3 7SF7
TM5 1081 V 5.40x40 ADGRL3 7SF7 - -
TM5 1082 G 5.41x41 ADGRL3 7SF7 ADGRL3 7SF7
TM5 1083 P 5.42x42 ADGRL3 7SF7 ADGRL3 7SF7
TM5 1084 A 5.43x43 ADGRL3 7SF7 ADGRL3 7SF7
TM5 1085 A 5.44x44 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM5 1086 V 5.45x45 ADGRL3 7SF7 - -
TM5 1087 I 5.46x46 ADGRL3 7SF7 ADGRL3 7SF7
TM5 1088 V 5.47x47 ADGRL3 7SF7 - -
TM5 1089 L 5.48x48 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM5 1090 V 5.49x49 ADGRL3 7SF7 calcitonin receptor-like receptor 7KNU
TM5 1091 N 5.50x50 ADGRL3 7SF7 ADGRL3 7SF7
TM5 1092 M 5.51x51 ADGRL3 7SF7 - -
TM5 1093 L 5.52x52 ADGRL3 7SF7 GLP-1 receptor 6LN2
TM5 1094 I 5.53x53 ADGRL3 7SF7 glucagon receptor 5YQZ
TM5 1095 G 5.54x54 ADGRL3 7SF7 - -
TM5 1096 I 5.55x55 ADGRL3 7SF7 PTH1 receptor 6FJ3
TM5 1097 I 5.56x56 ADGRL3 7SF7 ADGRL3 7SF7
TM5 1098 V 5.57x57 ADGRL3 7SF7 GLP-1 receptor 6LN2
TM5 1099 F 5.58x58 ADGRL3 7SF7 - -
TM5 1100 N 5.59x59 ADGRL3 7SF7 - -
TM5 1101 K 5.60x60 ADGRL3 7SF7 ADGRL3 7SF7
TM5 1102 L 5.61x61 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM5 1103 M 5.62x62 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM5 1104 A 5.63x63 ADGRL3 7SF7 glucagon receptor 5YQZ
TM5 1105 R 5.64x64 ADGRL3 7SF7 - -
TM5 1106 D 5.65x65 ADGRL3 7SF7 - -
TM5 1107 G 5.66x66 ADGRL3 7SF7 - -
TM5 1108 I 5.67x67 ADGRL3 7SF7 ADGRL3 7SF7
TM5 1109 S 5.68x68 ADGRL3 7SF7 - -
ICL3 1110 D - - - - -
ICL3 1111 K - - - - -
ICL3 1112 S - - - - -
ICL3 1113 K - - - - -
ICL3 1114 K - - - - -
ICL3 1144 S - - - - -
ICL3 1145 A - - - - -
ICL3 1146 S - - - - -
ICL3 1147 A - - - - -
ICL3 1148 R - - - - -
TM6 1149 N 6.34x34 ADGRL3 7SF7 ADGRL3 7SF7
TM6 1150 A 6.35x35 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM6 1151 M 6.36x36 ADGRL3 7SF7 calcitonin receptor-like receptor 7KNU
TM6 1152 A 6.37x37 ADGRL3 7SF7 - -
TM6 1153 S 6.38x38 ADGRL3 7SF7 - -
TM6 1154 L 6.39x39 ADGRL3 7SF7 - -
TM6 1155 W 6.40x40 ADGRL3 7SF7 - -
TM6 1156 S 6.41x41 ADGRL3 7SF7 glucagon receptor 5YQZ
TM6 1157 S 6.42x42 ADGRL3 7SF7 - -
TM6 1158 C 6.43x43 ADGRL3 7SF7 - -
TM6 1159 V 6.44x44 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM6 1160 V 6.45x45 ADGRL3 7SF7 - -
TM6 1161 L 6.46x46 ADGRL3 7SF7 ADGRL3 7SF7
TM6 1162 P 6.47x47 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM6 1163 L 6.48x48 ADGRL3 7SF7 ADGRL3 7SF7
TM6 1164 L 6.49x49 ADGRL3 7SF7 ADGRL3 7SF7
TM6 1165 A 6.50x50 ADGRL3 7SF7 - -
TM6 1166 L 6.51x51 ADGRL3 7SF7 ADGRL3 7SF7
TM6 1167 T 6.52x52 ADGRL3 7SF7 ADGRL3 7SF7
TM6 1168 W 6.53x53 ADGRL3 7SF7 ADGRL3 7SF7
TM6 1169 M 6.54x54 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM6 1170 S 6.55x55 ADGRL3 7SF7 - -
TM6 1171 A 6.56x56 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM6 1172 V 6.57x57 ADGRL3 7SF7 - -
TM6 1173 L 6.58x58 ADGRL3 7SF7 PTH1 receptor 6FJ3
ECL3 1174 A - - - - -
ECL3 1175 M - - - - -
ECL3 1176 T - - - - -
ECL3 1177 D - - - - -
ECL3 1178 R - - - - -
ECL3 1179 R - - - - -
TM7 1180 S 7.35x34 ADGRL3 7SF7 - -
TM7 1181 V 7.36x35 ADGRL3 7SF7 ADGRL3 7SF7
TM7 1182 L 7.37x36 ADGRL3 7SF7 - -
TM7 1183 F 7.38x37 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM7 1184 Q 7.39x38 ADGRL3 7SF7 - -
TM7 1185 A 7.40x39 ADGRL3 7SF7 - -
TM7 1186 L 7.41x40 ADGRL3 7SF7 ADGRL3 7SF7
TM7 1187 F 7.42x41 ADGRL3 7SF7 ADGRL3 7SF7
TM7 1188 A 7.43x42 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM7 1189 V 7.44x43 ADGRL3 7SF7 - -
TM7 1190 F 7.45x44 ADGRL3 7SF7 ADGRL3 7SF7
TM7 1191 N 7.46x45 ADGRL3 7SF7 ADGRL3 7SF7
TM7 1192 S 7.47x46 ADGRL3 7SF7 ADGRL3 7SF7
TM7 1193 A 7.48x47 ADGRL3 7SF7 - -
TM7 1194 Q 7.49x49 ADGRL3 7SF7 ADGRL3 7SF7
TM7 1195 G 7.50x50 ADGRL3 7SF7 ADGRL3 7SF7
TM7 1196 F 7.51x51 ADGRL3 7SF7 CRF1 receptor 4Z9G
TM7 1197 V 7.52x52 ADGRL3 7SF7 - -
TM7 1198 I 7.53x53 ADGRL3 7SF7 ADGRL3 7SF7
TM7 1199 T 7.54x54 ADGRL3 7SF7 - -
TM7 1200 A 7.55x55 ADGRL3 7SF7 - -
TM7 1201 V 7.56x56 ADGRL3 7SF7 - -
TM7 1202 H 7.57x57 ADGRL3 7SF7 ADGRL3 7SF7
TM7 1203 C 7.58x58 ADGRL3 7SF7 ADGRL3 7SF7
TM7 1204 F 7.59x59 ADGRL3 7SF7 CRF1 receptor 4K5Y
TM7 1205 L 7.60x60 ADGRL3 7SF7 ADGRL3 7SF7
H8 1206 R 8.47x47 ADGRL3 7SF7 - -
H8 1207 R 8.48x48 ADGRL3 7SF7 - -
H8 1208 E 8.49x49 ADGRL3 7SF7 calcitonin receptor-like receptor 7KNU
H8 1209 V 8.50x50 ADGRL3 7SF7 ADGRL3 7SF7
H8 1210 Q 8.51x51 ADGRL3 7SF7 calcitonin receptor-like receptor 7KNU
H8 1211 D 8.52x52 ADGRL3 7SF7 - -
H8 1212 V 8.53x53 ADGRL3 7SF7 - -
H8 1213 V 8.54x54 ADGRL3 7SF7 - -
H8 1214 K 8.55x55 ADGRL3 7SF7 PTH1 receptor 6FJ3
H8 1215 C 8.56x56 ADGRL3 7SF7 - -
H8 1216 Q 8.57x57 ADGRL3 7SF7 - -
H8 1217 M 8.58x58 ADGRL3 7SF7 - -
H8 1218 G 8.59x59 CRF1 receptor 6PB0 - -
H8 1219 V 8.60x60 CRF1 receptor 6PB0 - -
H8 1220 C 8.61x61 CRF1 receptor 6PB0 - -
H8 1221 R 8.62x62 CRF1 receptor 6PB0 glucagon receptor 4L6R
H8 1222 A 8.63x63 CRF1 receptor 6PB0 - -
C-term 1223 D - - - - -
C-term 1224 E - - - - -
C-term 1225 S - - - - -
C-term 1226 E - - - - -
C-term 1227 D - - - - -