OR1N1 (or1n1_human)

FAMILY

Class O2 (tetrapod specific odorant) Odorant receptors Odorant family 1 OR1N1

GENE

OR1N1 (OR1N3)

ORGANISM

Human (Homo sapiens)

ALT. NAMES

Olfactory receptor 1N1, Olfactory receptor 1-26, OR1-26, Olfactory receptor 1N3, Olfactory receptor OR9-22

SOURCE

SWISSPROT

SEQUENCE

N-term        
M
E
N
Q
S
S
I
S
E
F
10
              TM1
F
L
R
G
I
S
A
P
P
E
20
                   
Q
Q
Q
S
L
F
G
I
F
L
30
                   
C
M
Y
L
V
T
L
T
G
N
40
                   
L
L
I
I
L
A
I
G
S
D
50
ICL1 TM2      
L
H
L
H
T
P
M
Y
F
F
60
                   
L
A
N
L
S
F
V
D
M
G
70
                   
L
T
S
S
T
V
T
K
M
L
80
            ECL1
V
N
I
Q
T
R
H
H
T
I
90
TM3              
S
Y
T
G
C
L
T
Q
M
Y
100
                   
F
F
L
M
F
G
D
L
D
S
110
                   
F
F
L
A
A
M
A
Y
D
R
120
            ICL2
Y
V
A
I
C
H
P
L
C
Y
130
        TM4      
S
T
V
M
R
P
Q
V
C
A
140
                   
L
M
L
A
L
C
W
V
L
T
150
                   
N
I
V
A
L
T
H
T
F
L
160
      ECL2      
M
A
R
L
S
F
C
V
T
G
170
                   
E
I
A
H
F
F
C
D
I
T
180
                   
P
V
L
K
L
S
C
S
D
T
190
TM5              
H
I
N
E
M
M
V
F
V
L
200
                   
G
G
T
V
L
I
V
P
F
L
210
                   
C
I
V
T
S
Y
I
H
I
V
220
            ICL3
P
A
I
L
R
V
R
T
R
G
230
TM6              
G
V
G
K
A
F
S
T
C
S
240
                   
S
H
L
C
V
V
C
V
F
Y
250
                   
G
T
L
F
S
A
Y
L
C
P
260
ECL3 TM7      
P
S
I
A
S
E
E
K
D
I
270
                   
A
A
A
A
M
Y
T
I
V
T
280
                   
P
M
L
N
P
F
I
Y
S
L
290
  H8              
R
N
K
D
M
K
G
A
L
K
300
                   
R
L
F
S
H
R
S
I
V
S
310
C-term
S

LINKS

UniProt

DIAGRAMS

7TM

ICL1 L H L H ICL1ECL1 H H T I ECL1ICL2 P L C Y S T V M ICL2ECL2 L S F C V T G E I A H F F C D I T P V L K L S C S D ECL2ICL3 R T R G ICL3ECL3 C P P S I A ECL3N-term M E N Q S S I S E F F L R G I S A N-termC-term S C-term P P E Q Q Q S L F G I F L C M Y L V T L T G N L L I I L A I G S D T P M Y F F L A N L S F V D M G L T S S T V T K M L V N I Q T R S Y T G C L T Q M Y F F L M F G D L D S F F L A A M A Y D R Y V A I C H R P Q V C A L M L A L C W V L T N I V A L T H T F L M A R T H I N E M M V F V L G G T V L I V P F L C I V T S Y I H I V P A I L R V G V G K A F S T C S S H L C V V C V F Y G T L F S A Y L S E E K D I A A A A M Y T I V T P M L N P F I Y S L R N K D L K R R S I M K G A L F S H V S
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

L N G T L T V L Y M C L F I G F L S Q Q 1 A N L S F V D M G L T S S T V T K M L V 2 A A L F F S D L D G F M L F F Y M Q T L 3 C A L M L A L C W V L T N I V A L T H T 4 Y S T V I C L F P V I L V T G G L V F V 5 S S H L C V V C V F Y G T L F S A Y L 6 F P N L M P T V I T Y M A A A A I D K 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

or1n1_human active,

or1n1_human inactive

STRUCTURES

No structures available