OR1L8 (or1l8_human)
FAMILY
Class O2 (tetrapod specific odorant) Odorant receptors Odorant family 1 OR1L8
GENE
OR1L8
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Olfactory receptor 1L8, Olfactory receptor OR9-24
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
E
|
R
|
I
|
N
|
H
|
T
|
S
|
S
|
V
|
10 |
S
|
E
|
F
|
I
|
L
|
L
|
G
|
L
|
S
|
S
|
20 |
TM1 | |||||||||
R
|
P
|
E
|
D
|
Q
|
K
|
T
|
L
|
F
|
V
|
30 |
L
|
F
|
L
|
I
|
V
|
Y
|
L
|
V
|
T
|
I
|
40 |
T
|
G
|
N
|
L
|
L
|
I
|
I
|
L
|
A
|
I
|
50 |
ICL1 | TM2 | ||||||||
R
|
F
|
N
|
P
|
H
|
L
|
Q
|
T
|
P
|
M
|
60 |
Y
|
F
|
F
|
L
|
S
|
F
|
L
|
S
|
L
|
T
|
70 |
D
|
I
|
C
|
F
|
T
|
T
|
S
|
V
|
V
|
P
|
80 |
K
|
M
|
L
|
M
|
N
|
F
|
L
|
S
|
E
|
K
|
90 |
ECL1 | TM3 | ||||||||
K
|
T
|
I
|
S
|
Y
|
A
|
G
|
C
|
L
|
T
|
100 |
Q
|
M
|
Y
|
F
|
L
|
Y
|
A
|
L
|
G
|
N
|
110 |
S
|
D
|
S
|
C
|
L
|
L
|
A
|
V
|
M
|
A
|
120 |
F
|
D
|
R
|
Y
|
V
|
A
|
V
|
C
|
D
|
P
|
130 |
ICL2 | TM4 | ||||||||
F
|
H
|
Y
|
V
|
T
|
T
|
M
|
S
|
H
|
H
|
140 |
H
|
C
|
V
|
L
|
L
|
V
|
A
|
F
|
S
|
C
|
150 |
S
|
F
|
P
|
H
|
L
|
H
|
S
|
L
|
L
|
H
|
160 |
ECL2 | |||||||||
T
|
L
|
L
|
L
|
N
|
R
|
L
|
T
|
F
|
C
|
170 |
D
|
S
|
N
|
V
|
I
|
H
|
H
|
F
|
L
|
C
|
180 |
D
|
L
|
S
|
P
|
V
|
L
|
K
|
L
|
S
|
C
|
190 |
TM5 | |||||||||
S
|
S
|
I
|
F
|
V
|
N
|
E
|
I
|
V
|
Q
|
200 |
M
|
T
|
E
|
A
|
P
|
I
|
V
|
L
|
V
|
T
|
210 |
R
|
F
|
L
|
C
|
I
|
A
|
F
|
S
|
Y
|
I
|
220 |
R
|
I
|
L
|
T
|
T
|
V
|
L
|
K
|
I
|
P
|
230 |
TM6 | |||||||||
S
|
T
|
S
|
G
|
K
|
R
|
K
|
A
|
F
|
S
|
240 |
T
|
C
|
G
|
F
|
Y
|
L
|
T
|
V
|
V
|
T
|
250 |
L
|
F
|
Y
|
G
|
S
|
I
|
F
|
C
|
V
|
Y
|
260 |
ECL3 | TM7 | ||||||||
L
|
Q
|
P
|
P
|
S
|
T
|
Y
|
A
|
V
|
K
|
270 |
D
|
H
|
V
|
A
|
T
|
I
|
V
|
Y
|
T
|
V
|
280 |
L
|
S
|
S
|
M
|
L
|
N
|
P
|
F
|
I
|
Y
|
290 |
H8 | |||||||||
S
|
L
|
R
|
N
|
K
|
D
|
L
|
K
|
Q
|
G
|
300 |
L
|
R
|
K
|
L
|
M
|
S
|
K
|
R
|
S
|
LINKS
DIAGRAMS
7TM
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
No structures available